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    iPSC Gene Editing

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    Although both the iPSC and CRISPR technologies have advanced considerably recently, handling of iPSCs throughout the genome engineering process requires a special skill set for accurate genetic modification while maintaining the health and pluripotency of iPSC lines. This is where Creative Bioarray's expertise lies

    1876-1881: Domenico Lovisato and the geology of Calabria (southern Italy)

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    Celebrating the centennial of Domenico Lovisato’s death (1842-1916), this paper highlights the role played by this eminent Italian geologist as a pioneer for the geological knowledge of Calabria region (Southern Italy), a geologically complex area which became the subject of a long-lasting and still continuing debate. Lovisato spent only few years in Calabria (1876-1878) teaching as high school professor of mathematics; this period marked a turning point for his scientific growth representing a switch for his career from avocational to full-time geologist. This experience granted him the involvement in the academic career, with the enrollment in the University of Sassari and Cagliari as Professor of Mineralogy and Geology (from 1878 until his death, in 1916). Lovisato must be acknowledged as the author of the first 1:50,000 geological map of the Calabria region. As such, he should be mentioned for his ethic approach towards environment, anticipating the catastrophic effect of natural phenomena and the modern concepts of geoethic

    Report on Machine Learning techniques for astrophysical analyses - versione 1

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    Report sulle tecniche di Machine Learning per analisi astrofisiche

    Oncolytic Virus Service

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    Oncolytic viruses (OVs) are a class of viruses that can selectively replicate in and lyse cancer cells, and subsequent spread with a tumor while not causing damage to normal cells. They have tremendous therapeutic potential to target and kill cancerous cell. Oncolytic virotherapy is an innovative treatment modality which uses replication competent viruses to destroy malignant cancers

    Fermentation for Microbial Biomass

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    Creative Biogene has accumulated extensive and further experience in manufacturing microbial biomass and offers dedicated services for in-house or partnered microbial fermentation of live microorganisms

    Algorithm for creation of digital twin from UAV

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    The report specifically focuses on the creation of digital twins using UAV (Unmanned Aerial Vehicle) photogrammetry techniques. It offers functionalities for processing aerial imagery, generating 3D models, and creating digital representations of real-world environment

    iPSC Gene Editing

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    Creative Bioarray is an experienced and outstanding provider of iPSCs Gene Editing service. We are dedicated to providing quality data and comprehensive service for your scientific research, and we are pleased to use our extensive experience and advanced platform to offer the best service to satisfy each demand from our customers

    mRNA Synthesis

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    Synthetic mRNA has recently come into focus as a potential new drug class to deliver genetic information. Such synthetic mRNA can be engineered to transiently express proteins more rapidly and safety, due to no need of transnuclear localization and lack of integration into host cell genome. In addition, the development of in vitro transcription (IVT) technique renders the easy modulation of mRNA's biochemical properties. Throughout the IVT process, various modified nucleotides, for example 5-methylcytidine, 5-methoxyuridine and pseudouridine can be simply incorporated into the synthetic mRNA. Depending on the properties of chemically-modified nucleotides, the immunogenicity or stability of the resulting mRNA can be improved. Therefore, the synthetic mRNA has become much popular among a broad range of potential applications, such as regenerative medicine, basic cell biology, treatment of diseases, and reprogramming of cells

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