322 research outputs found
Structure and bonding of proximity-enforced main-group dimers stabilized by a rigid naphthyridine diimine ligand
- Publication venue
- 'Wiley'
- Publication date
- 01/09/2022
- Field of study
The development of ligands capable of effectively stabilizing highly reactive main-group species has led to the experimental realization of a variety of systems with fascinating properties. In this work, we computationally investigate the electronic, structural, energetic, and bonding features of proximity-enforced group 13–15 homodimers stabilized by a rigid expanded pincer ligand based on the 1,8-naphthyridine (napy) core. We show that the redox-active naphthyridine diimine (NDI) ligand enables a wide variety of structural motifs and element-element interaction modes, the latter ranging from isolated, element-centered lone pairs (e.g., E = Si, Ge) to cases where through-space π bonds (E = Pb), element-element multiple bonds (E = P, As) and biradical ground states (E = N) are observed. Our results hint at the feasibility of NDI-E2 species as viable synthetic targets, highlighting the versatility and potential applications of napy-based ligands in main-group chemistry
Modulation of the Naked-Eye and Fluorescence Color of a Protonated Boron-Doped Thiazolothiazole by Anion-Dependent Hydrogen Bonding
- Author
- Publication venue
- 'Wiley'
- Publication date
- 13/07/2022
- Field of study
The reaction of a cyclic alkyl(amino)carbene (CAAC)-stabilized thiazaborolo[5,4-d]thiazaborole (TzbTzb) with strong Brønsted acids, such as HCl, HOTf (Tf=O2SCF3) and [H(OEt2)2][BArF4] (ArF=3,5-(CF3)2C6H3), results in the protonation of both TzbTzb nitrogen atoms. In each case X-ray crystallographic data show coordination of the counteranions (Cl−, OTf−, BArF4−) or solvent molecules (OEt2) to the doubly protonated fused heterocycle via hydrogen-bonding interactions, the strength of which strongly influences the 1H NMR shift of the NH protons, enabling tuning of both the visible (yellow to red) and fluorescence (green to red) colors of these salts. DFT calculations reveal that the hydrogen bonding of the counteranion or solvent to the protonated nitrogen centers affects the intramolecular TzbTzb-to-CAAC charge transfer character involved in the S0→S1 transition, ultimately enabling fine-tuning of their absorption and emission spectral features
Translating advances in the molecular basis of schizophrenia into novel cognitive treatment strategies
- Author
- Abdolmaleky
- Abe
- Alexander
- Alexander
- Alexander
- Alexander
- Alexander
- Allen
- Anagnostaras
- Babovic
- Bado
- Ballard
- Barch
- Bartko
- Basu
- Beaulieu
- Bogdan
- Bugarski-Kirola
- Bugarski-Kirola
- Burdick
- Cannon
- Carpenter
- Carr
- Carter
- Chen
- Chong
- Chong
- Chubb
- Clapcote
- Clifton
- CNV and Schizophrenia Working Groups of the Psychiatric Genomics Consortium
- Cohen
- Cope
- Cosgrove
- Cui
- Cuthbert
- Devaraju
- Devito
- Downing
- Duan
- Duffy
- Dunlop
- Egerton
- El-Ghundi
- Evensen
- Falkenberg
- Farrell
- Fernandes
- Freedman
- Fromer
- Fujioka
- Gatt
- Genovese
- Ghoshal
- Glahn
- Gogos
- Gong
- Gonzalez-Burgos
- Gottesman
- Gould
- Grannan
- Green
- Hahn
- Hall
- Hall
- Harris
- Harrison
- Harrison
- Hennah
- Holmes
- Hopkins
- Howes
- Howes
- Hoyle
- Iacono
- Iacono
- International Schizophrenia Consortium
- Iwakura
- Jentsch
- Johnson
- Johnson
- Johnstone
- Jonas
- Jones
- Kaiser
- Kao
- Karam
- Karlsgodt
- Kato
- Kern
- Kinon
- Kirov
- Kleinman
- Kogan
- Koike
- Krivoy
- Krivoy
- Kunii
- Kvajo
- Labrie
- Law
- Law
- Law
- Lee
- Lencz
- Lerner
- Lewis
- Li
- Li
- Li
- Lieblich
- Lin
- Lipina
- Long
- Maric
- McCarroll
- Meechan
- Meechan
- Mei
- Mexal
- Miyakawa
- Moore
- Moran
- Moran
- Morris
- Mostaid
- Muir
- Mukai
- Munafò
- Neddens
- Neddens
- Nicodemus
- Nicodemus
- Nong
- Nuechterlein
- Nuechterlein
- O'Tuathaigh
- O'Tuathaigh
- O'Tuathaigh
- Ouchi
- Pan
- Papaleo
- Papaleo
- Papaleo
- Papaleo
- Papaleo
- Park
- Parlapani
- Paterlini
- Paterson
- Patil
- Pei
- Petit
- Piskorowski
- Pletnikov
- Porteous
- Pratt
- Preskorn
- Prickaerts
- Pritchett
- Pritchett
- Pull
- Rafter
- Reynolds
- Ribeiz
- Rosell
- Ruderfer
- Sarter
- Schizophrenia Working Group of the Psychiatric Genomics Consortium
- Schlumberger
- Schneider
- Schubert
- Seamans
- Ser
- Shekhar
- Shiraishi
- Shirey
- Sigurdsson
- Singer
- Singer
- Singh
- Siuta
- Southan
- Stark
- Stauffer
- Stefanis
- Stroup
- Su
- Suzuki
- Svensson
- Takao
- Talbot
- Talbot
- Tamura
- Tandon
- Tang
- Tost
- Tunbridge
- Turetsky
- Urs
- Urs
- Veerman
- Vijayraghavan
- Waddington
- Walling
- Walsh
- Walters
- Wang
- Wang
- Weickert
- Weickert
- Weinberg
- Weinstein
- Weiser
- Winchester
- Woolley
- Xu
- Yee
- Young
- Young
- Young
- Young
- Young
- Young
- Young
- Zai
- Zhang
- Zhou
- Publication venue
- 'Wiley'
- Publication date
- 01/07/2017
- Field of study
The presence and severity of cognitive symptoms, including working memory, executive dysfunction and attentional impairment, contributes materially to functional impairment in schizophrenia. Cognitive symptoms have proven resistant to both first- and second-generation antipsychotic drugs. Efforts to develop a consensus set of cognitive domains that are both disrupted in schizophrenia and are amenable to cross-species validation (e.g. the NIMH CNTRICS and RDoC initiatives) are an important step towards standardisation of outcome measures that can used in preclinical testing of new drugs. While causative genetic mutations have not been identified, new technologies have identified novel genes as well as hitherto candidate genes previously implicated in the pathophysiology of schizophrenia and/or mechanisms of antipsychotic efficacy. This review comprises a selective summary of these developments, particularly phenotypic data arising from preclinical genetic models for cognitive dysfunction in schizophrenia, with the aim of indicating potential new directions for pro-cognitive therapeutics
High incidence of septic shock caused by Streptococcus pneumoniae serotype 3 - a retrospective epidemiological study
- Author
- AB Brueggemann
- AG Jansen
- Arne Forsgren
- BHH Claesson
- C Garcia-Vidal
- C Weil-Olivier
- DE Briles
- DM Weinberger
- DR Feikin
- EHJ Lund
- Fredrik Resman
- G Kahlmeter
- Inga Odenholt
- J Poolman
- JN Weiser
- Jonas Ahl
- K Sjostrom
- Kristian Riesbeck
- M Inghammar
- MBM Furebring
- Nils Littorin
- P Martens
- R Austrian
- RP Dellinger
- RPS Dagan
- S Berg
- S Ruckinger
- SP Halbert
- SR Alanee
- T van der Poll
- WB Wood Jr
- ZB Harboe
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk
- Author
- Adolfsson Rolf
- Agartz Ingrid
- Agerbo Esben
- Albus Margot
- Alexander Madeline
- Als Thomas D.
- Amin Farooq
- Andreassen Ole A.
- Bacanu Silviu A.
- Baekvad-Hansen Marie
- Begemann Martin
- Belliveau Richard A.
- Bene Judit
- Bergen Sarah E.
- Bevilacqua Elizabeth
- Bigdeli Tim B.
- Black Donald W.
- Blackwood Douglas H. R.
- Boocock James
- Borglum Anders D.
- Borglum Anders D.
- Bramon Elvira
- Bruggeman Richard
- Buccola Nancy G.
- Buckner Randy L.
- Bulik-Sullivan Brendan
- Buxbaum Joseph D.
- Buxbaum Joseph D.
- Bybjerg-Grauholm Jonas
- Byerley William
- Cahn Wiepke
- Cai Guiqing
- Campion Dominique
- Cantor Rita M.
- Carr Vaughan J.
- Carrera Noa
- Catts Stanley
- Chambert Kimberly D.
- Chan Raymond C. K.
- Chen Eric Y. H.
- Chen Ronald Y. L.
- Cheng Wei
- Cheung Eric F. C.
- Chong Siow Ann
- Cichon Sven
- Cloninger C. Robert
- Cohen David
- Cohen Nadine
- Collier David A.
- Cormican Paul
- Corvin Aiden
- Cox Nancy J.
- Craddock Nick
- Crowley James J.
- Curtis David
- Daly Mark J.
- Dang Kristen K.
- Darvasi Ariel
- Davidson Michael
- Davis Kenneth L.
- de Haan Lieuwe
- Degenhardt Franziska
- Del Favero Jurgen
- Demontis Ditte
- Devlin Bernie
- Dikeos Dimitris
- Dinan Timothy
- Djurovic Srdjan
- Dobbyn Amanda
- Domenici Enrico
- Domenici Enrico
- Donohoe Gary
- Drapeau Elodie
- Duan Jubao
- Dudbridge Frank
- Durmishi Naser
- Ehrenreich Hannelore
- Eichhammer Peter
- Eriksson Johan
- Escott-Price Valentina
- Esko Tonu
- Essioux Laurent
- Essioux Laurent
- Fanous Ayman H.
- Farh Kai-How
- Farrell Martilias S.
- Frank Josef
- Franke Lude
- Freedman Robert
- Freimer Nelson B.
- Friedl Marion
- Friedman Joseph
- Fromer Menachem
- Fromer Menachem
- Gamazon Eric R.
- Gejman Pablo
- Genovese Giulio
- Georgieva Lyudmila
- Giegling Ina
- Gill Michael
- Girdhar Kiran
- Giusti-Rodriguez Paola
- Godard Stephanie
- Goldstein Jacqueline
- Golimbet Vera
- Gopal Srihari
- Gratten Jacob
- Grove Jakob
- Gur Raquel E.
- Gurling Hugh
- Hahn Chang-Gyu
- Hammer Christian
- Hamshere Marian L.
- Hansen Christine Soholm
- Hansen Mark
- Hansen Thomas
- Haroutunian Vahram
- Haroutunian Vahram
- Hartmann Annette M.
- Henskens Frans A.
- Herms Stefan
- Hirai Keisuke
- Hirschhorn Joel N.
- Hoffman Gabriel
- Hoffmann Per
- Hofman Andrea
- Hollegaard Mads
- Holmans Peter A.
- Hougaard David M.
- Huang Hailiang
- Huckins Laura M.
- Hultman Christina M.
- Ikeda Masashi
- Im Hae Kyung
- Iwata Nakao
- Jablensky Assen
- Joa Inge
- Johnson Jessica S.
- Jonsson Erik G.
- Julia Antonio
- Kahler Anna K.
- Kahn Rene S.
- Kalaydjieva Luba
- Karachanak-Yankova Sena
- Karjalainen Juha
- Kavanagh David
- Keller Matthew C.
- Kendler Kenneth S.
- Kennedy James L.
- Keong Jimmy Lee Chee
- Khrunin Andrey
- Kim Yunjung
- Kirov George
- Klein Lambertus L.
- Klovins Janis
- Knight Jo
- Knowles James A.
- Konte Bettina
- Kramer Robin
- Kucinskas Vaidutis
- Kucinskiene Zita Ausrele
- Kuzelova-Ptackova Hana
- Laurent Claudine
- Lee Phil
- Lee S. Hong
- Legge Sophie E.
- Lencz Todd
- Lerer Bernard
- Levinson Douglas F.
- Lewis David A.
- Li Miaoxin
- Li Qingqin S.
- Li Tao
- Liang Kung-Yee
- Lieberman Jeffrey
- Limborska Svetlana
- Lipska Barbara K.
- Liu Jianjun
- Logsdon Benjamin A.
- Lonnqvist Jouko
- Loughland Carmel M.
- Lubinski Jan
- Macek Milan
- Magnusson Patrik K. E.
- Mahajan Milind C.
- Maher Brion S.
- Maier Wolfgang
- Malhotra Anil K.
- Mallet Jacques
- Mangravite Lara M.
- Marsal Sara
- Mattheisen Manuel
- Mattingsdal Morten
- McCarley Robert W.
- McCarroll Steven A.
- McDonald Colm
- McIntosh Andrew M.
- McQuillin Andrew
- Meier Sandra
- Meijer Carin J.
- Melegh Bela
- Melle Ingrid
- Mesholam-Gately Raquelle I.
- Metspalu Andres
- Michie Patricia T.
- Milani Lili
- Milanova Vihra
- Mokrab Younes
- Moran Jennifer L.
- Morris Derek W.
- Mors Ole
- Mors Ole
- Mortensen Preben B.
- Mortensen Preben Bo
- Mowry Bryan J.
- Muller-Myhsok Bertram
- Murphy Kieran C.
- Murray Robin M.
- Myin-Germeys Inez
- Neale Benjamin M.
- Nelis Mari
- Nenadic Igor
- Nertney Deborah A.
- Nestadt Gerald
- Nguyen Hoang T.
- Nicodemus Kristin K.
- Nikitina-Zake Liene
- Nisenbaum Laura
- Nordentoft Merete
- Nordin Annelie
- Nothen Markus M.
- O'Callaghan Eadbhard
- O'Donovan Michael C.
- O'Dushlaine Colm
- O'Neill F. Anthony
- Oh Sang-Yun
- Olincy Ann
- Olsen Line
- Ophoff Roel A.
- Owen Michael J.
- Owen Michael J.
- Palotie Aarno
- Pantelis Christos
- Papadimitriou George N.
- Papiol Sergi
- Pardinas Antonio F.
- Parkhomenko Elena
- Pato Carlos N.
- Pato Michele T.
- Paunio Tiina
- Pedersen Carsten Bocker
- Pedersen Marianne Giortz
- Pejovic-Milovancevic Milica
- Perkins Diana O.
- Pers Tune H.
- Perumal Thanneer M.
- Peters Mette A.
- Petryshen Tracey L.
- Pietilainen Olli
- Pimm Jonathan
- Pocklington Andrew J.
- Posthuma Danielle
- Powell John
- Price Alkes
- Pulver Ann E.
- Purcell Shaun
- Purcell Shaun M.
- Quested Digby
- Rajagopal Veera M.
- Rajagopal Veera Manikandan
- Rasmussen Henrik B.
- Reichenberg Abraham
- Reimers Mark A.
- Richards Alexander L.
- Rietschel Marcella
- Riley Brien P.
- Ripke Stephan
- Roffman Joshua L.
- Roussos Panos
- Ruderfer Douglas M.
- Ruderfer Douglas M.
- Rujescu Dan
- Salomaa Veikko
- Sanders Alan R.
- Schadt Eric
- Schall Ulrich
- Schubert Christian R.
- Schulze Thomas G.
- Schwab Sibylle G.
- Scolnick Edward M.
- Scott Rodney J.
- Seidman Larry J.
- Shah Hardik R.
- Sham Pak C.
- Shi Jianxin
- Sieberts Solveig K.
- Sigurdsson Engilbert
- Silagadze Teimuraz
- Silverman Jeremy M.
- Sim Kang
- Sklar Pamela
- Slominsky Petr
- Smoller Jordan W.
- So Hon-Cheong
- Soderman Erik
- Spencer Chris C. A.
- St Clair David
- Stahl Eli A.
- Stefansson Hreinn
- Stefansson Kari
- Steinberg Stacy
- Stogmann Elisabeth
- Straub Richard E.
- Strengman Eric
- Strohmaier Jana
- Stroup T. Scott
- Subramaniam Mythily
- Sullivan Patrick
- Sullivan Patrick F.
- Suvisaari Jaana
- Svrakic Dragan M.
- Szatkiewicz Jin P.
- Thirumalai Srinivas
- Toncheva Draga
- Tosato Sarah
- Toyoshiba Hiroyoshi
- Van Os Jim
- Veijola Juha
- Visscher Peter M.
- Waddington John
- Walsh Dermot
- Walters James T. R.
- Wang Dai
- Wang Qiang
- Wang Weiqing
- Webb Bradley T.
- Weinberger Daniel R.
- Weiser Mark
- Wendland Jens R.
- Werge Thomas
- Werge Thomas
- Wildenauer Dieter B.
- Williams Nigel M.
- Williams Stephanie
- Witt Stephanie H.
- Wolen Aaron R.
- Wong Emily H. M.
- Wormley Brandon K.
- Wray Naomi R.
- Xi Hualin Simon
- Zai Clement C.
- Zheng Xuebin
- Zimprich Fritz
- Publication venue
- Ludwig-Maximilians-Universität München
- Publication date
- 01/04/2019
- Field of study
Transcriptomic imputation approaches combine eQTL reference panels with large-scale genotype data in order to test associations between disease and gene expression. These genic associations could elucidate signals in complex genome-wide association study (GWAS) loci and may disentangle the role of different tissues in disease development. We used the largest eQTL reference panel for the dorso-lateral prefrontal cortex (DLPFC) to create a set of gene expression predictors and demonstrate their utility. We applied DLPFC and 12 GTEx-brain predictors to 40,299 schizophrenia cases and 65,264 matched controls for a large transcriptomic imputation study of schizophrenia. We identified 413 genic associations across 13 brain regions. Stepwise conditioning identified 67 non-MHC genes, of which 14 did not fall within previous GWAS loci. We identified 36 significantly enriched pathways, including hexosaminidase-A deficiency, and multiple porphyric disorder pathways. We investigated developmental expression patterns among the 67 non-MHC genes and identified specific groups of pre- and postnatal expression
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
- Author
- Adams Mark
- Adolfsson Rolf
- Agartz Ingrid
- Agerbo Esben
- Al Eissa Mariam
- Albus Margot
- Alexander Madeline
- Alizadeh Behrooz Z
- Alptekin Köksal
- Als Thomas D
- Amin Farooq
- Andreassen Ole A
- Arango Celso
- Arolt Volker
- Arrojo Manuel
- Atbaşoğlu Eşref Cem
- Athanasiu Lavinia
- Atkinson Elizabeth G
- Awasthi Swapnil
- Ayub Muhammad
- Azevedo Maria Helena
- Bacanu Silviu A
- Bass Nicholas J
- Baune Bernhard T
- Begemann Martin
- Belangero Sintia Iole
- Belliveau Richard A
- Bene Judit
- Benner Christian
- Benyamin Beben
- Bergen Sarah E
- Bertolino Alessandro
- Bigdeli Tim B
- Black Donald W
- Blasi Giuseppe
- Bobes Julio
- Bonassi Stefano
- Braff David
- Bramon Elvira
- Braun Alice
- Bray Nicholas J
- Breen Gerome
- Bressan Rodrigo Affonseca
- Bromet Evelyn J
- Bruggeman Richard
- Bryois Julien
- Buccola Nancy G
- Buckley Peter F
- Buckner Randy L
- Buxbaum Joseph D
- Bybjerg-Grauholm Jonas
- Byerley William F
- Børglum Anders D
- Cahn Wiepke
- Cairns Murray J
- Calkins Monica E
- Campion Dominique
- Carr Vaughan J
- Castle David
- Catts Stanley V
- Cervilla Jorge A
- Chambert Kimberley D
- Chan Raymond CK
- Chaumette Boris
- Chen Chia-Yen
- Chen Wei J
- Cheng Wei
- Cheung Eric FC
- Chong Siow Ann
- Cichon Sven
- Cloninger C Robert
- Cohen David
- Collier David A
- Consoli Angèle
- Cordeiro Quirino
- Corvin Aiden
- Costas Javier
- Crespo-Facorro Benedicto
- Curtis Charles
- Curtis David
- Daly Mark J
- Davidson Michael
- Davis Kenneth L
- de Haan Lieuwe
- Degenhardt Franziska
- DeLisi Lynn E
- Demontis Ditte
- Dennison Charlotte A
- Dickerson Faith
- Dikeos Dimitris
- Dinan Timothy
- Djurovic Srdjan
- Domenici Enrico
- Donohoe Gary
- Duan Jubao
- Ducci Giuseppe
- Dudbridge Frank
- Ehrenreich Hannelore
- Eriksson Johan G
- Escott-Price Valentina
- Esko Tõnu
- Fanous Ayman H
- Faraone Stephen V
- Fañanás Lourdes
- Fiorentino Alessia
- Forstner Andreas
- Forti Marta Di
- Frank Josef
- Freedman Robert
- Frei Oleksandr
- Freimer Nelson B
- Fromer Menachem
- Frustaci Alessandra
- Gadelha Ary
- Galletly Cherrie
- Gandal Michael J
- Gareeva Anna
- Gawlik Micha
- Ge Tian
- Gejman Pablo V
- Gennarelli Massimo
- Genovese Giulio
- Gershon Elliot S
- Giannitelli Marianna
- Giegling Ina
- Gill Michael
- Giusti-Rodríguez Paola
- Glatt Stephen J
- Godard Stephanie
- Goldstein Jacqueline I
- Golimbet Vera
- González Peñas Javier
- González-Pinto Ana
- Gopal Srihari
- Gratten Jacob
- Green Michael F
- Greenwood Tiffany A
- Grove Jakob
- Guillin Olivier
- Gur Raquel E
- Gur Ruben C
- Gutiérrez Blanca
- Gülöksüz Sinan
- Hahn Eric
- Hakonarson Hakon
- Hall Lynsey S
- Haroutunian Vahram
- Hartmann Annette M
- Harvey Carol
- Harwood Janet C
- Hayward Caroline
- Henskens Frans A
- Herms Stefan
- Hoffmann Per
- Holmans Peter A
- Hong Kyung Sue
- Hougaard David M
- Howrigan Daniel P
- Huang Hailiang
- Hultman Christina M
- Hwu Hai-Gwo
- Hyman Steven E
- Ikeda Masashi
- Indonesia Schizophrenia Consortium
- Iwata Nakao
- Iyegbe Conrad
- Jablensky Assen V
- Joa Inge
- Julià Antonio
- Jönsson Erik G
- Kahn René S
- Kam-Thong Tony
- Kamatani Yoichiro
- Karachanak-Yankova Sena
- Kebir Oussama
- Keller Matthew C
- Kelly Brian J
- Kendler Kenneth S
- Kennedy James L
- Khrunin Andrey
- Khusnutdinova Elza
- Kim Minsoo
- Kim Sung-Wan
- Kirov George
- Klovins Janis
- Knowles James A
- Kondratiev Nikolay
- Konte Bettina
- Koopmans Frank
- Kraft Julia
- Krebs Marie-Odile
- Kubo Michiaki
- Kusumawardhani Agung
- Kuzelova-Ptackova Hana
- Kučinskas Vaidutis
- Kučinskiene Zita Ausrele
- Kähler Anna K
- Lam Max
- Landi Stefano
- Laurent-Levinson Claudine
- Lazzeroni Laura C
- Lee Jimmy
- Lee Phil H
- Legge Sophie E
- Lehrer Douglas S
- Lencer Rebecca
- Lencz Todd
- Lerer Bernard
- Levinson Douglas F
- Li Miaoxin
- Li Qingqin S
- Li Zhiqiang
- Lieberman Jeffrey
- Light Gregory A
- Limborska Svetlana
- Liu Chih-Min
- Liu Jianjun
- Loughland Carmel M
- Lubinski Jan
- Luykx Jurjen J
- Lynham Amy
- Lönnqvist Jouko
- Macek Milan
- Mackinnon Andrew
- Magnusson Patrik KE
- Magnusson Sigurdur
- Maher Brion S
- Maier Wolfgang
- Malaspina Dolores
- Malhotra Anil K
- Malhotra Dheeraj
- Mallet Jacques
- Marder Stephen R
- Marsal Sara
- Martin Alicia R
- Martorell Lourdes
- Mattheisen Manuel
- McCarley Robert W
- McCarroll Steven A
- McDonald Colm
- McGrath John J
- McIntosh Andrew
- McQuillin Andrew
- Medeiros Helena
- Meier Sandra
- Melegh Bela
- Melle Ingrid
- Menezes Paulo R
- Mesholam-Gately Raquelle I
- Metspalu Andres
- Michie Patricia T
- Milani Lili
- Milanova Vihra
- Mitjans Marina
- Molden Espen
- Molina Esther
- Molto María Dolores
- Mondelli Valeria
- Moran Jennifer L
- Moreno Carmen
- Morgan Vera A
- Morley Christopher P
- Morris Derek W
- Mors Ole
- Mortensen Preben B
- Mowry Bryan J
- Muntané Gerard
- Murphy Kieran C
- Murray Robin M
- Myin-Germeys Inez
- Müller-Myhsok Bertram
- Neale Benjamin M
- Neil Amanda L
- Nenadić Igor
- Nestadt Gerald
- Nikitina-Zake Liene
- Nimgaonkar Vishwajit
- Nordentoft Merete
- Noto Cristiano
- Nuechterlein Keith H
- Nöthen Markus M
- O'Brien Niamh Louise
- O'Donovan Michael C
- O'Neill F Anthony
- Oh Sang-Yun
- Olincy Ann
- Ophoff Roel A
- Ota Vanessa Kiyomi
- Owen Michael J
- Paciga Sara A
- Palotie Aarno
- Panagiotaropoulou Georgia
- Pantelis Christos
- Papadimitriou George N
- Pardiñas Antonio F
- Parellada Mara
- Pato Carlos N
- Pato Michele T
- Paunio Tiina
- Pellegrino Renata
- Periyasamy Sathish
- Perkins Diana O
- Petryshen Tracey L
- Pfuhlmann Bruno
- Pietiläinen Olli
- Pimm Jonathan
- Pirinen Matti
- Pocklington Andrew J
- Porteous David
- Posthuma Danielle
- Powell John
- PsychENCODE
- Psychosis Endophenotypes International Consortium
- Pulver Ann E
- Qi Ting
- Qin Shengying
- Quattrone Diego
- Quested Digby
- Radant Allen D
- Rampino Antonio
- Rapaport Mark H
- Rautanen Anna
- Reichenberg Abraham
- Richards Alexander L
- Rietschel Marcella
- Riley Brien P
- Ripke Stephan
- Rivera Margarita
- Roe Cheryl
- Roffman Joshua L
- Roth Julian
- Rothermundt Matthias
- Roussos Panos
- Rujescu Dan
- Rutten Bart PF
- Saka Meram C
- Saker-Delye Safaa
- Salomaa Veikko
- Sanders Alan R
- Sanjuan Julio
- Santoro Marcos Leite
- Savitz Adam
- Schall Ulrich
- Schizophrenia Working Group of the Psychiatric Genomics Consorti
- Schulze Thomas G
- Schwab Sibylle G
- Scott Rodney J
- Seidman Larry J
- Serretti Alessandro
- Sham Pak C
- Sharp Sally Isabel
- Shi Jianxin
- Shi Yongyong
- Sidorenko Julia
- Siever Larry J
- Sigurdsson Engilbert
- Silverman Jeremy M
- Sim Kang
- Skarabis Nora
- Slominsky Petr
- Smoller Jordan W
- So Hon-Cheong
- Sobell Janet L
- St Clair David
- Stahl Eli A
- Stain Helen J
- Steen Nils Eiel
- Stefansson Kari
- Stefánsson Hreinn
- Steixner-Kumar Agnes A
- Stone William S
- Straub Richard E
- Streit Fabian
- Strengman Eric
- Stroup T Scott
- Stögmann Elisabeth
- Subramaniam Mythily
- Sugar Catherine A
- Sullivan Patrick F
- Suvisaari Jaana
- Svrakic Dragan M
- Swerdlow Neal R
- SynGO Consortium
- Szatkiewicz Jin P
- Söderman Erik
- Ta Thi Minh Tam
- Takahashi Atsushi
- Terao Chikashi
- Thibaut Florence
- Toncheva Draga
- Tooney Paul A
- Torretta Silvia
- Tosato Sarah
- Trubetskoy Vassily
- Tsuang Debby W
- Tsuang Ming T
- Tura Gian Battista
- Turetsky Bruce I
- Vaaler Arne
- van Amelsvoort Therese
- van Os Jim
- van Winkel Ruud
- Vassos Evangelos
- Vawter Marquis P
- Veijola Juha
- Verhage Matthijs
- Vilella Elisabet
- Visscher Peter M
- Voloudakis Georgios
- Waddington John
- Walter Henrik
- Walters James TR
- Wang Shi-Heng
- Watanabe Kyoko
- Waterreus Anna
- Webb Bradley T
- Weinberger Daniel R
- Weiser Mark
- Werge Thomas
- Wildenauer Dieter B
- Williams Nigel M
- Witt Stephanie H
- Wormley Brandon K
- Wray Naomi R
- Wu Jing Qin
- Wu Yang
- Xu Shuhua
- Xu Zhida
- Yang Jian
- Yolken Robert
- Yu Xin
- Yue Weihua
- Zai Clement C
- Zeng Jian
- Zhang Wen
- Zhou Wei
- Zhu Feng
- Zimprich Fritz
- Üçok Alp
- Publication venue
- NATURE PORTFOLIO
- Publication date
- 21/04/2022
- Field of study
Schizophrenia has a heritability of 60-80%1, much of which is attributable to common risk alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with schizophrenia and 243,649 control individuals, we report common variant associations at 287 distinct genomic loci. Associations were concentrated in genes that are expressed in excitatory and inhibitory neurons of the central nervous system, but not in other tissues or cell types. Using fine-mapping and functional genomic data, we identify 120 genes (106 protein-coding) that are likely to underpin associations at some of these loci, including 16 genes with credible causal non-synonymous or untranslated region variation. We also implicate fundamental processes related to neuronal function, including synaptic organization, differentiation and transmission. Fine-mapped candidates were enriched for genes associated with rare disruptive coding variants in people with schizophrenia, including the glutamate receptor subunit GRIN2A and transcription factor SP4, and were also enriched for genes implicated by such variants in neurodevelopmental disorders. We identify biological processes relevant to schizophrenia pathophysiology; show convergence of common and rare variant associations in schizophrenia and neurodevelopmental disorders; and provide a resource of prioritized genes and variants to advance mechanistic studies
Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector
- Author
- Aaboud Morad
- Aad Georges
- Abbott Brad
- Abdinov Ovsat
- Abeloos Baptiste
- Abidi Syed
- AbouZeid Ossama
- Abraham Nicola
- Abramowicz Halina
- Abreu Henso
- Abreu Ricardo
- Abulaiti Yiming
- Acharya Bobby
- Adachi Shunsuke
- Adamczyk Leszek
- Adelman Jahred
- Adersberger Michael
- Adye Tim
- Affolder Tony
- Afik Yoav
- Agatonovic-Jovin Tatjana
- Agheorghiesei Catalin
- Aguilar-Saavedra Juan
- Ahlen Steven
- Ahmadov Faig
- Aielli Giulio
- Akatsuka Shunichi
- Akerstedt Henrik
- Akilli Ece
- Akimov Andrei
- Alberghi Gian
- Albert Justin
- Albicocco Pietro
- Alconada Verzini Maria
- Alderweireldt Sara
- Aleksa Martin
- Aleksandrov Igor
- Alexa Calin
- Alexander Gideon
- Alexopoulos Theodoros
- Alhroob Muhammad
- Ali Babar
- Aliev Malik
- Alimonti Gianluca
- Alison John
- Alkire Steven
- Allbrooke Benedict
- Allen Benjamin
- Allport Phillip
- Aloisio Alberto
- Alonso Alejandro
- Alonso Francisco
- Alpigiani Cristiano
- Alshehri Azzah
- Alstaty Mahmoud
- Alvarez Gonzalez Barbara
- Alviggi Mariagrazia
- Amadio Brian
- Amaral Coutinho Yara
- Amelung Christoph
- Amidei Dante
- Amor Dos Santos Susana
- Amoroso Simone
- Anastopoulos Christos
- Ancu Lucian
- Andari Nansi
- Andeen Timothy
- Anders Christoph
- Anders John
- Anderson Kelby
- Andreazza Attilio
- Andrei George
- Angelidakis Stylianos
- Angelozzi Ivan
- Angerami Aaron
- Anisenkov Alexey
- Anjos Nuno
- Annovi Alberto
- Antel Claire
- Antonelli Mario
- Antonov Alexey
- Antrim Daniel
- Anulli Fabio
- Aoki Masato
- Aperio Bella Ludovica
- Arabidze Giorgi
- Arai Yasuo
- Araque Juan
- Araujo Ferraz Victor
- Arce Ayana
- Ardell Rose
- Arduh Francisco
- Arguin Jean-Francois
- Argyropoulos Spyridon
- Arik Metin
- Armbruster Aaron
- Armitage Lewis
- Arnaez Olivier
- Arnold Hannah
- Arratia Miguel
- Arslan Ozan
- Artamonov Andrei
- Artoni Giacomo
- Artz Sebastian
- Asai Shoji
- Asbah Nedaa
- Ashkenazi Adi
- Asquith Lily
- Assamagan Ketevi
- Astalos Robert
- Atkinson Markus
- Atlay Naim
- Augsten Kamil
- Avolio Giuseppe
- Axen Bradley
- Ayoub Mohamad
- Azuelos Georges
- Baas Alessandra
- Baca Matthew
- Bachacou Henri
- Bachas Konstantinos
- Backes Moritz
- Bagnaia Paolo
- Bahmani Marzieh
- Bahrasemani Sina
- Baines John
- Bajic Milena
- Baker Oliver
- Bakker Pepijn
- Baldin Evgenii
- Balek Petr
- Balli Fabrice
- Balunas William
- Banas Elzbieta
- Bandyopadhyay Anjishnu
- Banerjee Swagato
- Bannoura Arwa
- Barak Liron
- Barberio Elisabetta
- Barberis Dario
- Barbero Marlon
- Barillari Teresa
- Barisits Martin-Stefan
- Barkeloo Jason
- Barklow Timothy
- Barlow Nick
- Barnes Sarah
- Barnett Bruce
- Barnett Michael
- Barnovska-Blenessy Zuzana
- Baroncelli Antonio
- Barone Gaetano
- Barr Alan
- Barranco Navarro Laura
- Barreiro Guimarães da Costa João
- Barreiro Fernando
- Barros Vale Maria
- Bartoldus Rainer
- Barton Adam
- Bartos Pavol
- Basalaev Artem
- Bassalat Ahmed
- Bates Richard
- Batista Santiago
- Batley Richard
- Battaglia Marco
- Bauce Matteo
- Bauer Florian
- Bawa Harinder
- Beacham James
- Beattie Michael
- Beau Tristan
- Beauchemin Pierre-Hugues
- Bechtle Philip
- Beck Hans~Peter
- Beck Helge
- Becker Kathrin
- Becker Maurice
- Becot Cyril
- Beddall Andrew
- Beddall Ayda
- Bednyakov Vadim
- Bedognetti Matteo
- Bee Christopher
- Beermann Thomas
- Begalli Marcia
- Begel Michael
- Behr Janna
- Bell Andrew
- Bella Gideon
- Bellagamba Lorenzo
- Bellerive Alain
- Bellomo Massimiliano
- Belotskiy Konstantin
- Beltramello Olga
- Belyaev Nikita
- Benary Odette
- Benchekroun Driss
- Bender Michael
- Benekos Nektarios
- Benhammou Yan
- Benhar Noccioli Eleonora
- Benitez Jose
- Benjamin Douglas
- Benoit Mathieu
- Bensinger James
- Bentvelsen Stan
- Beresford Lydia
- Beretta Matteo
- Berge David
- Bergeaas Kuutmann Elin
- Berger Nicolas
- Bergsten Laura
- Beringer Jürg
- Berlendis Simon
- Bernard Nathan
- Bernardi Gregorio
- Bernius Catrin
- Bernlochner Florian
- Berry Tracey
- Berta Peter
- Bertella Claudia
- Bertoli Gabriele
- Bertram Iain
- Bertsche Carolyn
- Besjes Geert-Jan
- Bessidskaia Bylund Olga
- Bessner Martin
- Besson Nathalie
- Bethani Agni
- Bethke Siegfried
- Betti Alessandra
- Bevan Adrian
- Beyer Julien-christopher
- Bianchi Riccardo-Maria
- Biebel Otmar
- Biedermann Dustin
- Bielski Rafal
- Bierwagen Katharina
- Biesuz Nicolo
- Biglietti Michela
- Billoud Thomas
- Bilokon Halina
- Bindi Marcello
- Bingul Ahmet
- Bini Cesare
- Biondi Silvia
- Bisanz Tobias
- Bittrich Carsten
- Bjergaard David
- Black James
- Black Kevin
- Blair Robert
- Blazek Tomas
- Bloch Ingo
- Blocker Craig
- Blue Andrew
- Blumenschein Ulrike
- Blunier Sylvain
- Bobbink Gerjan
- Bobrovnikov Victor
- Bocchetta Simona
- Bocci Andrea
- Bock Christopher
- Boehler Michael
- Boerner Daniela
- Bogavac Danijela
- Bogdanchikov Alexander
- Bohm Christian
- Boisvert Veronique
- Bokan Petar
- Bold Tomasz
- Boldyrev Alexey
- Bolz Arthur
- Bomben Marco
- Bona Marcella
- Boonekamp Maarten
- Borisov Anatoly
- Borissov Guennadi
- Bortfeldt Jonathan
- Bortoletto Daniela
- Bortolotto Valerio
- Boscherini Davide
- Bosman Martine
- Bossio Sola Jonathan
- Boudreau Joseph
- Bouhova-Thacker Evelina
- Boumediene Djamel
- Bourdarios Claire
- Boutle Sarah
- Boveia Antonio
- Boyd James
- Boyko Igor
- Bozson Adam
- Bracinik Juraj
- Brandt Andrew
- Brandt Gerhard
- Brandt Oleg
- Braren Frued
- Bratzler Uwe
- Brau Benjamin
- Brau James
- Breaden Madden William
- Brendlinger Kurt
- Brennan Amelia
- Brenner Lydia
- Brenner Richard
- Bressler Shikma
- Briglin Daniel
- Bristow Timothy
- Britton Dave
- Britzger Daniel
- Brochu Frederic
- Brock Ian
- Brock Raymond
- Brooijmans Gustaaf
- Brooks Timothy
- Brooks William
- Brosamer Jacquelyn
- Brost Elizabeth
- Broughton James
- Bruckman de Renstrom Pawel
- Bruncko Dusan
- Bruni Alessia
- Bruni Graziano
- Bruni Lucrezia
- Bruno Salvatore
- Brunt Benjamin
- Bruschi Marco
- Bruscino Nello
- Bryant Patrick
- Bryngemark Lene
- Buanes Trygve
- Buat Quentin
- Buchholz Peter
- Buckley Andrew
- Budagov Ioulian
- Buehrer Felix
- Bugge Magnar
- Bulekov Oleg
- Bullock Daniel
- Burch Tyler
- Burdin Sergey
- Burgard Carsten
- Burger Angela
- Burghgrave Blake
- Burka Klaudia
- Burke Stephen
- Burmeister Ingo
- Burr Jonathan
- Bussey Peter
- Butler John
- Buttar Craig
- Butterworth Jonathan
- Butti Pierfrancesco
- Buttinger William
- Buzatu Adrian
- Buzykaev Aleksey
- Büscher Daniel
- Büscher Volker
- C-Q Changqiao
- Cabrera Urbán Susana
- Caforio Davide
- Cai Huacheng
- Cairo Valentina
- Cakir Orhan
- Calace Noemi
- Calafiura Paolo
- Calandri Alessandro
- Calderini Giovanni
- Calfayan Philippe
- Callea Giuseppe
- Caloba Luiz
- Calvente Lopez Sergio
- Calvet David
- Calvet Samuel
- Calvet Thomas
- Camacho Toro Reina
- Camarda Stefano
- Camarri Paolo
- Cameron David
- Caminal Armadans Roger
- Camincher Clement
- Campana Simone
- Campanelli Mario
- Camplani Alessandra
- Campoverde Angel
- Canale Vincenzo
- Cano Bret Marc
- Cantero Josu
- Cao Tingting
- Capeans Garrido Maria
- Caprini Irinel
- Caprini Mihai
- Capua Marcella
- Carbone Ryne
- Cardarelli Roberto
- Cardillo Fabio
- Carli Ina
- Carli Tancredi
- Carlino Gianpaolo
- Carlson Benjamin
- Carminati Leonardo
- Carney Rebecca
- Caron Sascha
- Carquin Edson
- Carrillo-Montoya German
- Carrá Sonia
- Casadei Diego
- Casado Maria
- Casha Albert
- Casolino Mirkoantonio
- Casper David
- Castelijn Remco
- Castillo Gimenez Victoria
- Castro Nuno
- Catinaccio Andrea
- Catmore James
- Cattai Ariella
- Caudron Julien
- Cavaliere Viviana
- Cavallaro Emanuele
- Cavalli Donatella
- Cavalli-Sforza Matteo
- Cavasinni Vincenzo
- Celebi Emre
- Ceradini Filippo
- Cerda Alberich Leonor
- Cerri Alessandro
- Cerrito Lucio
- Cerutti Fabio
- Cervelli Alberto
- Cetin Serkant
- Chafaq Aziz
- Chakraborty Dhiman
- Chan Stephen
- Chan Wing
- Chan Yat
- Chang Philip
- Chapman John
- Charlton Dave
- Chau Chav
- Chavez Barajas Carlos
- Che Siinn
- Cheatham Susan
- Chegwidden Andrew
- Chekanov Sergei
- Chekulaev Sergey
- Chelkov Gueorgui
- Chelstowska Magda
- Chen Cheng
- Chen Chunhui
- Chen Hucheng
- Chen Jing
- Chen Shenjian
- Chen Shion
- Chen Xin
- Chen Ye
- Cheng Hok
- Cheng Huajie
- Cheplakov Alexander
- Cheremushkina Evgeniya
- Cherkaoui El Moursli Rajaa
- Cheu Elliott
- Cheung Kingman
- Chevalier Laurent
- Chiarella Vitaliano
- Chiarelli Giorgio
- Chiodini Gabriele
- Chisholm Andrew
- Chitan Adrian
- Chiu Yu
- Chizhov Mihail
- Choi Kyungeon
- Chomont Arthur
- Chouridou Sofia
- Chow Yun
- Christodoulou Valentinos
- Chu Ming
- Chudoba Jiri
- Chuinard Annabelle
- Chwastowski Janusz
- Chytka Ladislav
- Ciftci Abbas
- Cinca Diane
- Cindro Vladimir
- Cioara Irina
- Ciocio Alessandra
- Cirotto Francesco
- Citron Zvi
- Citterio Mauro
- Ciubancan Mihai
- Clark Allan
- Clark Brian
- Clark Michael
- Clark Philip
- Clarke Robert
- Clement Christophe
- Coadou Yann
- Cobal Marina
- Coccaro Andrea
- Cochran James
- Colasurdo Luca
- Cole Brian
- Colijn Auke-Pieter
- Collot Johann
- Colombo Tommaso
- Conde Muiño Patricia
- Coniavitis Elias
- Connell Simon
- Connelly Ian
- Constantinescu Serban
- Conti Geraldine
- Conventi Francesco
- Cooke Mark
- Cooper-Sarkar Amanda
- Cormier Felix
- Cormier Kyle
- Corradi Massimo
- Corriveau Francois
- Cortes-Gonzalez Arely
- Costa Giuseppe
- Costa María
- Costanzo Davide
- Cottin Giovanna
- Cowan Glen
- Cox Brian
- Cranmer Kyle
- Crawley Samuel
- Creager Rachael
- Cree Graham
- Crescioli Francesco
- Cribbs Wayne
- Cristinziani Markus
- Croft Vince
- Crosetti Giovanni
- Crépé-Renaudin Sabine
- Cueto Ana
- Cuhadar Donszelmann Tulay
- Cukierman Aviv
- Cummings Jane
- Curatolo Maria
- Czekierda Sabina
- Czodrowski Patrick
- Cúth Jakub
- D'amen Gabriele
- D'Auria Saverio
- D'Eramo Louis
- D'Onofrio Monica
- Da Cunha Sargedas De Sousa Mario
- Da Via Cinzia
- Dabrowski Wladyslaw
- Dado Tomas
- Dai Tiesheng
- Dale Orjan
- Dallaire Frederick
- Dallapiccola Carlo
- Dam Mogens
- Dandoy Jeffrey
- Daneri Maria
- Dang Nguyen
- Daniells Andrew
- Dann Nicholas
- Danninger Matthias
- Dano Hoffmann Maria
- Dao Valerio
- Darbo Giovanni
- Darmora Smita
- Dassoulas James
- Dattagupta Aparajita
- Daubney Thomas
- Davey Will
- David Claire
- Davidek Tomas
- Davis Douglas
- Davison Peter
- Dawe Edmund
- Dawson Ian
- de Asmundis Riccardo
- De Benedetti Abraham
- De Castro Stefano
- De Cecco Sandro
- De Groot Nicolo
- De Jong Paul
- De la Torre Hector
- De Lorenzi Francesco
- De Maria Antonio
- De Pedis Daniele
- De Salvo Alessandro
- De Sanctis Umberto
- De Santo Antonella
- De Vasconcelos Corga Kevin
- De Vivie De Regie Jean-Baptiste
- De Kaushik
- Debbe Ramiro
- Debenedetti Chiara
- Dedovich Dmitri
- Dehghanian Nooshin
- Deigaard Ingrid
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- Del Peso Jose
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- Deliot Frederic
- Delitzsch Chris
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- Dell'Asta Lidia
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- della Volpe Domenico
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- Demers Sarah
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- Demilly Aurelien
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- Derendarz Dominik
- Derkaoui Jamal
- Derue Frederic
- Dervan Paul
- Desch Klaus
- Deterre Cecile
- Dette Karola
- Devesa Maria
- Deviveiros Pier-Olivier
- Dewhurst Alastair
- Dhaliwal Saminder
- Di Bello Francesco
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- Di Ciaccio Lucia
- Di Clemente William
- Di Donato Camilla
- Di Girolamo Alessandro
- Di Girolamo Beniamino
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- Di Nardo Roberto
- Di Petrillo Karri
- Di Simone Andrea
- Di Sipio Riccardo
- Di Valentino David
- Diaconu Cristinel
- Diamond Miriam
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- Dickinson Jennet
- Diehl Edward
- Dietrich Janet
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- Dingfelder Jochen
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- Djobava Tamar
- Djuvsland Julia
- Dobos Daniel
- Dobre Monica
- Dodsworth David
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- Doyle Tony
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- Dubreuil Arnaud
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- Duckeck Guenter
- Ducourthial Audrey
- Ducu Otilia
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- Dudarev Alexey
- Dudder Andreas
- Duffield Emily
- Duflot Laurent
- Dulsen Carsten
- Dumancic Mirta
- Dumitriu Ana
- Duncan Anna
- Dunford Monica
- Duperrin Arnaud
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- Durglishvili Archil
- Duschinger Dirk
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- Dyndal Mateusz
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- Díez Cornell Sergio
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- Ekelof Tord
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- Ellert Mattias
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- Ellinghaus Frank
- Elliot Alison
- Ellis Nicolas
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- Elsing Markus
- Emeliyanov Dmitry
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- Erdmann Johannes
- Ereditato Antonio
- Ernst Michael
- Errede Steven
- Escalier Marc
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- Esposito Bellisario
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- Etienvre Anne-Isabelle
- Etzion Erez
- Evans Hal
- Ezhilov Alexey
- Ezzi Mohammed
- Fabbri Federica
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- Fabiani Veronica
- Facini Gabriel
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- Falla Rebecca
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- Farbin Amir
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- Farina Christian
- Farina Edoardo
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- Farthouat Philippe
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- Fassouliotis Dimitrios
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- Favareto Andrea
- Fawcett William
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- Filipuzzi Marco
- Filipčič Andrej
- Filthaut Frank
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- Finelli Kevin
- Fiolhais Miguel
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- Fischer Adam
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- Fisher Wade
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- Freund Benjamin
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- Frost James
- Fukunaga Chikara
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- Förster Fabian
- Gabizon Ofir
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- Gabrielli Andrea
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- Gadatsch Stefan
- Gadomski Szymon
- Gagliardi Guido
- Gagnon Louis
- Galea Cristina
- Galhardo Bruno
- Gallas Elizabeth
- Gallop Bruce
- Gallus Petr
- Galster Gorm
- Gan Kk
- Ganguly Sanmay
- Gao Yanyan
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- Garay Walls Francisca
- Garcia-Sciveres Maurice
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- Giagu Stefano
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- Gibson Stephen
- Gignac Matthew
- Gilchriese Murdock
- Gillberg Dag
- Gilles Geoffrey
- Gingrich Douglas
- Giordani MarioPaolo
- Giorgi Filippo
- Giraud Pierre-Francois
- Giromini Paolo
- Giugliarelli Gilberto
- Giugni Danilo
- Giuli Francesco
- Giuliani Claudia
- Giulini Maddalena
- Gjelsten Børge
- Gkaitatzis Stamatios
- Gkialas Ioannis
- Gkougkousis Evangelos
- Gkountoumis Panagiotis
- Gladilin Leonid
- Glasman Claudia
- Glatzer Julian
- Glaysher Paul
- Glazov Alexandre
- Goblirsch-Kolb Maximilian
- Godlewski Jan
- Goldfarb Steven
- Golling Tobias
- Golubkov Dmitry
- Gomes Agostinho
- Goncalves Gama Rafael
- Goncalves Pinto Firmino Da Costa Joao
- Gonella Giulia
- Gonella Laura
- Gongadze Alexi
- Gonnella Francesco
- Gonski Julia
- Gonzalez-Sevilla Sergio
- González de la Hoz Santiago
- Gonçalo Ricardo
- Goossens Luc
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- Gorini Benedetto
- Gorini Edoardo
- Gorišek Andrej
- Goshaw Alfred
- Gostkin Mikhail
- Gottardo Carlo
- Goudet Christophe
- Goujdami Driss
- Goussiou Anna
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- Yamamoto Akira
- Yamamoto Shimpei
- Yamanaka Takashi
- Yamane Fumiya
- Yamatani Masahiro
- Yamazaki Tomohiro
- Yamazaki Yuji
- Yan Zhen
- Yang Haijun
- Yang Hongtao
- Yang Yi
- Yang Zongchang
- Yao Weiming
- Yap Yee
- Yasu Yoshiji
- Yatsenko Elena
- Yau Wong Kaven
- Ye Jingbo
- Ye Shuwei
- Yeletskikh Ivan
- Yigitbasi Efe
- Yildirim Eda
- Yorita Kohei
- Yoshihara Keisuke
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- Young Christopher
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- Yuen Stephanie
- Yusuff Imran
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- Zaidan Remi
- Zaitsev Alexander
- Zakharchuk Nataliia
- Zalieckas Justas
- Zaman Aungshuman
- Zambito Stefano
- Zanzi Daniele
- Zeitnitz Christian
- Zemaityte Gabija
- Zemla Andrzej
- Zeng Jian
- Zeng Qi
- Zenin Oleg
- Zerwas Dirk
- Zhang Dengfeng
- Zhang Dongliang
- Zhang Fangzhou
- Zhang Guangyi
- Zhang Huijun
- Zhang Jinlong
- Zhang Lei
- Zhang Liqing
- Zhang Matt
- Zhang Peng
- Zhang Rui
- Zhang Ruiqi
- Zhang Xueyao
- Zhang Yu
- Zhang Zhiqing
- Zhao Xiandong
- Zhao Yongke
- Zhao Zhengguo
- Zhemchugov Alexey
- Zhou Bing
- Zhou Chen
- Zhou Li
- Zhou Maosen
- Zhou Mingliang
- Zhou Ning
- Zhou You
- Zhu Cheng
- Zhu Hongbo
- Zhu Junjie
- Zhu Yingchun
- Zhuang Xuai
- Zhukov Konstantin
- Zibell Andre
- Zieminska Daria
- Zimine Nikolai
- Zimmermann Christoph
- Zimmermann Stephanie
- Zinonos Zinonas
- Zinser Markus
- Ziolkowski Michael
- Zobernig Georg
- Zoccoli Antonio
- Zou Rui
- zur Nedden Martin
- Zwalinski Lukasz
- Åkesson Torsten
- Šfiligoj Tina
- Ženiš Tibor
- Živković Lidija
- Άlvarez Piqueras Damián
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2017
- Field of study
A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements
Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders
- Author
- Adams Mark J
- Adan Roger A H
- Adolfsson Annelie Nordin
- Adolfsson Rolf
- Agartz Ingrid
- Agerbo Esben
- Akil Huda
- Albani Diego
- Alda Martin
- Alexander Madeline
- Alfredsson Lars
- Als Thomas D
- Andlauer Till F M
- Ando Tetsuya
- Andreassen Ole A
- Androutsos Christos
- Anjorin Adebayo
- Anney Richard J L
- Anttila Verneri
- Arking Dan E
- Arnold Paul D
- Arranz M. J.
- Artigas Maria Soler
- Aschauer Harald
- Asherson Philip
- Backlund Lena
- Baker Jessica H
- Baldursson Gísli
- Banaschewski Tobias
- Barr Cathy L
- Barta Csaba
- Bass Nicholas
- Bauer Michael
- Baune Bernhard T
- Begemann Martin
- Belangero Sintia
- Bellgrove Mark
- Belliveau Richard A
- Bellivier Frank
- Bencko Vladimir
- Bergen Andrew W
- Bergen Sarah E
- Berger Klaus
- Berrettini Wade H
- Bettella Francesco
- Bey Katharina
- Bienvenu O Joseph
- Biernacka Joanna M
- Binder Elisabeth B
- Birgegård Andreas
- Black Donald W
- Blackwood Douglas H R
- Boomsma Dorret I
- Bramon Elvira
- Brandt Harry
- Breen Gerome
- Brown Lawrence W
- Buccola Nancy G
- Budde Monika
- Budman Cathy
- Buitelaar Jan
- Bulik Cynthia M
- Bunney William
- Burghardt Roland
- Burmeister Margit
- Burton Christie L
- Buxbaum Joseph D
- Bybjerg-Grauholm Jonas
- Byerley William
- Byrne Enda M
- Bækvad-Hansen Marie
- Bøen Erlend
- Børglum Anders D
- Cairns Murray J
- Campion Dominique
- Carlberg Laura
- Carr Vaughan J
- Casas Miquel
- Cassina Matteo
- Castelao Enrique
- Cath Danielle
- Cerrato Felecia
- Chambert Kimberly
- Cheon Keun-Ah
- Christensen Jane H
- Churchhouse Claire
- Cichon Sven
- Ciullo Valentina
- Clarke Toni-Kim
- Clementi Maurizio
- Cloninger C Robert
- Coffey Barbara J
- Cohen David
- Coleman Jonathan R I
- Collier David A
- Collins Ryan L
- Colodro-Conde Lucía
- Cook Edwin H
- Coon Hilary
- Coppola Giovanni
- Cormand Bru
- Corvin Aiden
- Courtet Philippe
- Craddock Nicholas
- Crawford Steven
- Crosbie Jennifer
- Crow Scott
- Crowley James J
- Curtis David
- Cusi Daniele
- Czerski Piotr M
- Dale Anders M
- Dalkner Nina
- Dalsgaard Søren
- Daly Mark J
- Danner Unna N
- Dannlowski Udo
- Davis Lea K
- Davis Oliver S P
- de Geus E. J. C.
- De Rubeis Silvia
- Degenhardt Franziska
- Degortes Daniela
- DeLisi Lynn E
- Delorme Richard
- Demontis Ditte
- Denys Damiaan
- Depienne Christel
- Derks Eske M
- DeSocio Janiece E
- Di Florio Arianna
- Dick Danielle M
- Dietrich Andrea
- Dina Christian
- Direk Nese
- Docampo Elisa
- Docherty Anna R
- Domenici Enrico
- Domschke Katharina
- Donohoe Gary
- Doyle Alysa E
- Duan Jubao
- Dudbridge Frank
- Dumont Ashley
- Duncan Laramie E
- Dunn Erin C
- Eapen Valsamma
- Edenberg Howard J
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- Zhu Zhaozhong
- Zinner Samuel H
- Zipfel Stephan
- Publication venue
- Publication date
- 01/01/2019
- Field of study
Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting substantial pleiotropy of contributing loci. However, the nature and mechanisms of these pleiotropic effects remain unclear. We performed analyses of 232,964 cases and 494,162 controls from genome-wide studies of anorexia nervosa, attention-deficit/hyper-activity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, and Tourette syndrome. Genetic correlation analyses revealed a meaningful structure within the eight disorders, identifying three groups of inter-related disorders. Meta-analysis across these eight disorders detected 109 loci associated with at least two psychiatric disorders, including 23 loci with pleiotropic effects on four or more disorders and 11 loci with antagonistic effects on multiple disorders. The pleiotropic loci are located within genes that show heightened expression in the brain throughout the lifespan, beginning prenatally in the second trimester, and play prominent roles in neurodevelopmental processes. These findings have important implications for psychiatric nosology, drug development, and risk prediction.Peer reviewe
Global baryon number conservation encoded in net-proton fluctuations measured in Pb–Pb collisions at √sNN = 2.76 TeV
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- Yuncu A.
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- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2020
- Field of study
Experimental results are presented on event-by-event net-proton fluctuation measurements in Pb–Pb collisions at √SNN=2.76 TeV, recorded by the ALICE detector at the CERN LHC. These measurements have as their ultimate goal an experimental test of Lattice QCD (LQCD) predictions on second and higher order cumulants of net-baryon distributions to search for critical behavior near the QCD phase boundary. Before confronting them with LQCD predictions, account has to be taken of correlations stemming from baryon number conservation as well as fluctuations of participating nucleons. Both effects influence the experimental measurements and are usually not considered in theoretical calculations. For the first time, it is shown that event-by-event baryon number conservation leads to subtle long-range correlations arising from very early interactions in the collisions.publishedVersio
Azimuthal anisotropy of charged jet production in root s(NN)=2.76 TeV Pb-Pb collisions
- Author
- Adam Jaroslav
- Adamova Dagmar
- Aggarwal Madan Mohan
- Aglieri Rinella Gianluca
- Agnello Michelangelo
- Agrawal Neelima
- Ahammed Zubayer
- Ahn Sang Un
- Aiola Salvatore
- Akindinov Alexander
- Alam Sk Noor
- Alarcon Do Passo Suaide Alexandre
- Aleksandrov Dmitry
- Alessandro Bruno
- Alexandre Didier
- Alfaro Molina Jose Ruben
- ALICE Collaboration
- Alici Andrea
- Alkin Anton
- Alme Johan
- Alt Torsten
- Altinpinar Sedat
- Altsybeev Igor
- Alves Garcia Prado Caio
- Andrei Cristian
- Andronic Anton
- Anguelov Venelin
- Anielski Jonas
- Anticic Tome
- Antinori Federico
- Antonioli Pietro
- Aphecetche Laurent Bernard
- Appelshaeuser Harald
- Araujo Silva Figueredo Marcel
- Arcelli Silvia
- Arnaldi Roberta
- Arnold Oliver Werner
- Arsene Ionut Cristian
- Arslandok Mesut
- Audurier Benjamin
- Augustinus Andre
- Averbeck Ralf Peter
- Azmi Mohd Danish
- Badala Angela
- Baek Yong Wook
- Bagnasco Stefano
- Bailhache Raphaelle Marie
- Bala Renu
- Baldisseri Alberto
- Baral Rama Chandra
- Barbano Anastasia Maria
- Barbera Roberto
- Barile Francesco
- Barnafoldi Gergely Gabor
- Barnby Lee Stuart
- Bartalini Paolo
- Barth Klaus
- Bartke Jerzy Gustaw
- Bartsch Esther
- Bashir Butt Jamila
- Basile Maurizio
- Bastid Nicole
- Basu Sumit
- Bathen Bastian
- Batigne Guillaume
- Batista Camejo Arianna
- Batyunya Boris
- Batzing Paul Christoph
- Bearden Ian Gardner
- Beck Hans
- Bedda Cristina
- Behera Nirbhay Kumar
- Belikov Iouri
- Bellini Francesca
- Bello Martinez Hector
- Bellwied Rene
- Belmont Iii Ronald John
- Belmont Moreno Ernesto
- Belyaev Vladimir
- Bencedi Gyula
- Beole Stefania
- Berceanu Ionela
- Bercuci Alexandru
- Berdnikov Yaroslav
- Berenyi Daniel
- Bertens Redmer Alexander
- Berzano Dario
- Betev Latchezar
- Bhasin Anju
- Bhat Inayat Rasool
- Bhati Ashok Kumar
- Bhattacharjee Buddhadeb
- Bhom Jihyun
- Bianchi Livio
- Bianchi Nicola
- Bianchin Chiara
- Bielcik Jaroslav
- Bielcikova Jana
- Bilandzic Ante
- Biswas Rathijit
- Biswas Saikat
- Bjelogrlic Sandro
- Blair Justin Thomas
- Blau Dmitry
- Blume Christoph
- Bock Friederike
- Boettger Stefan
- Bogdanov Alexey
- Boggild Hans
- Boldizsar Laszlo
- Bombara Marek
- Book Julian Heinz
- Borel Herve
- Borissov Alexander
- Borri Marcello
- Bossu Francesco
- Botta Elena
- Bourjau Christian
- Braun-Munzinger Peter
- Bregant Marco
- Breitner Timo Gunther
- Broker Theo Alexander
- Browning Tyler Allen
- Broz Michal
- Brucken Erik Jens
- Bruna Elena
- Bruno Giuseppe Eugenio
- Budnikov Dmitry
- Buesching Henner
- Bufalino Stefania
- Buncic Predrag
- Busch Oliver
- Buthelezi Edith Zinhle
- Buxton Jesse Thomas
- Cabanillas Noris Juan Carlos
- Caffarri Davide
- Cai Xu
- Caines Helen Louise
- Calero Diaz Liliet
- Caliva Alberto
- Calvo Villar Ernesto
- Camerini Paolo
- Carena Francesco
- Carena Wisla
- Carnesecchi Francesca
- Castillo Castellanos Javier Ernesto
- Castro Andrew John
- Casula Ester Anna Rita
- Ceballos Sanchez Cesar
- Cepila Jan
- Cerello Piergiorgio
- Cerkala Jakub
- Chang Beomsu
- Chapeland Sylvain
- Chartier Marielle
- Charvet Jean-Luc Fernand
- Chattopadhyay Subhasis
- Chattopadhyay Sukalyan
- Chelnokov Volodymyr
- Cherney Michael Gerard
- Cheshkov Cvetan Valeriev
- Cheynis Brigitte
- Chibante Barroso Vasco Miguel
- Cho Soyeon
- Chochula Peter
- Choi Kyungeon
- Chojnacki Marek
- Choudhury Subikash
- Christakoglou Panagiotis
- Christensen Christian Holm
- Christiansen Peter
- Chujo Tatsuya
- Chung Suh-Urk
- Chunhui Zhang
- Cicalo Corrado
- Cifarelli Luisa
- Cindolo Federico
- Cleymans Jean Willy Andre
- Colamaria Fabio Filippo
- Colella Domenico
- Collu Alberto
- Colocci Manuel
- Conesa Balbastre Gustavo
- Conesa Del Valle Zaida
- Connors Megan Elizabeth
- Contreras Nuno Jesus Guillermo
- Cormier Thomas Michael
- Corrales Morales Yasser
- Correia Zanoli Henrique Jose
- Cortes Maldonado Ismael
- Cortese Pietro
- Cosentino Mauro Rogerio
- Costa Filippo
- Crochet Philippe
- Cruz Albino Rigoberto
- Cuautle Flores Eleazar
- Cunqueiro Mendez Leticia
- Dahms Torsten
- Dainese Andrea
- Danu Andrea
- Das Debasish
- Das Indranil
- Das Supriya
- Dash Ajay Kumar
- Dash Sadhana
- De Caro Annalisa
- De Cataldo Giacinto
- De Conti Camila
- De Cuveland Jan
- De Falco Alessandro
- De Gruttola Daniele
- De Marco Nora
- De Pasquale Salvatore
- De Sudipan
- Deisting Alexander
- Deloff Andrzej
- Denes Ervin Sandor
- Deplano Caterina
- Dhankher Preeti
- Di Bari Domenico
- Di Mauro Antonio
- Di Nezza Pasquale
- Diaz Corchero Miguel Angel
- Dietel Thomas
- Dillenseger Pascal
- Diozcora Vargas Trevino Aurora
- Divia Roberto
- Djuvsland Oeystein
- Dobrigkeit Chinellato David
- Dobrin Alexandru Florin
- Domenicis Gimenez Diogenes
- Donigus Benjamin
- Dordic Olja
- Drozhzhova Tatiana
- Dubey Anand Kumar
- Dubla Andrea
- Ducroux Laurent
- Dupieux Pascal
- Ehlers Iii Raymond James
- Elia Domenico
- Engel Heiko
- Epple Eliane
- Erazmus Barbara Ewa
- Erdemir Irem
- Erhardt Filip
- Espagnon Bruno
- Estienne Magali Danielle
- Esumi Shinichi
- Eum Jongsik
- Evans David
- Evdokimov Sergey
- Eyyubova Gyulnara
- Fabbietti Laura
- Fabris Daniela
- Faivre Julien
- Fantoni Alessandra
- Fasel Markus
- Feldkamp Linus
- Feliciello Alessandro
- Feofilov Grigorii
- Ferencei Jozef
- Fernandez Tellez Arturo
- Ferreira Natal Da Luz Pedro Hugo
- Ferretti Alessandro
- Festanti Andrea
- Feuillard Victor Jose Gaston
- Figiel Jan
- Filchagin Sergey
- Finogeev Dmitry
- Fionda Fiorella
- Fiore Enrichetta Maria
- Fleck Martin Gabriel
- Floris Michele
- Foertsch Siegfried Valentin
- Foka Panagiota
- Fokin Sergey
- Fragiacomo Enrico
- Francescon Andrea
- Frankenfeld Ulrich Michael
- Fuchs Ulrich
- Furget Christophe
- Furs Artur
- Fusco Girard Mario
- Gaardhoeje Jens Joergen
- Gagliardi Martino
- Gago Medina Alberto Martin
- Gallio Mauro
- Gameiro Munhoz Marcelo
- Gangadharan Dhevan Raja
- Ganoti Paraskevi
- Gao Chaosong
- Garabatos Cuadrado Jose
- Garcia-Solis Edmundo Javier
- Gargiulo Corrado
- Gasik Piotr Jan
- Gauger Erin Frances
- Germain Marie
- Gheata Andrei George
- Gheata Mihaela
- Ghosh Premomoy
- Ghosh Sanjay Kumar
- Gianotti Paola
- Giubellino Paolo
- Giubilato Piero
- Gladysz-Dziadus Ewa
- Glassel Peter
- Gomez Coral Diego Mauricio
- Gomez Ramirez Andres
- Gonzalez Ferreiro Elena
- Gonzalez Zamora Pedro
- Gonzalez Victor
- Gorbunov Sergey
- Gorlich Lidia Maria
- Gotovac Sven
- Grabski Varlen
- Grachov Oleg Anatolievich
- Graczykowski Lukasz Kamil
- Graham Katie Leanne
- Grelli Alessandro
- Grigoras Alina Gabriela
- Grigoras Costin
- Grigoryan Ara
- Grigoryan Smbat
- Grigoryev Vladislav
- Grion Nevio
- Gronefeld Julius Maximilian
- Grosse-Oetringhaus Jan Fiete
- Grossiord Jean-Yves
- Grosso Raffaele
- Grynyov Borys
- Guber Fedor
- Guernane Rachid
- Guerzoni Barbara
- Gulbrandsen Kristjan Herlache
- Gunji Taku
- Gupta Anik
- Gupta Ramni
- Haake Rudiger
- Haaland Oystein Senneset
- Hadjidakis Cynthia Marie
- Haiduc Maria
- Hamagaki Hideki
- Hamar Gergoe
- Harris John William
- Harton Austin Vincent
- Hatzifotiadou Despina
- Hayashi Shinichi
- Heckel Stefan Thomas
- Heide Markus Ansgar
- Helstrup Haavard
- Herghelegiu Andrei Ionut
- Herrera Corral Gerardo Antonio
- Hess Benjamin Andreas
- Hetland Kristin Fanebust
- Hillemanns Hartmut
- Hippolyte Boris
- Hosokawa Ritsuya
- Hristov Peter Zahariev
- Huang Meidana
- Humanic Thomas
- Hussain Nur
- Hussain Tahir
- Hutter Dirk
- Hwang Dae Sung
- Ilkaev Radiy
- Inaba Motoi
- Ippolitov Mikhail
- Irfan Muhammad
- Ivanov Marian
- Ivanov Vladimir
- Izucheev Vladimir
- Jacobs Peter Martin
- Jadhav Manoj Bhanudas
- Jadlovska Slavka
- Jadlovsky Jan
- Jahnke Cristiane
- Jakubowska Monika Joanna
- Jang Haeng Jin
- Janik Malgorzata Anna
- Jena Chitrasen
- Jena Satyajit
- Jimenez Bustamante Raul Tonatiuh
- Jones Peter Graham
- Jung Hyungtaik
- Jusko Anton
- Kalinak Peter
- Kalweit Alexander Philipp
- Kamin Jason Adrian
- Kang Ju Hwan
- Kaplin Vladimir
- Kar Somnath
- Karasu Uysal Ayben
- Karavichev Oleg
- Karavicheva Tatiana
- Karayan Lilit
- Karpechev Evgeny
- Kebschull Udo Wolfgang
- Keidel Ralf
- Keijdener Darius Laurens
- Keil Markus
- Khan Mohammed Mohisin
- Khan Palash
- Khan Shuaib Ahmad
- Khanzadeev Alexei
- Kharlov Yury
- Kileng Bjarte
- Kim Daehyeok
- Kim Do Won
- Kim Dong Jo
- Kim Hyeonjoong
- Kim Jinsook
- Kim Mimae
- Kim Minwoo
- Kim Se Yong
- Kim Taesoo
- Kirsch Stefan
- Kisel Ivan
- Kiselev Sergey
- Kisiel Adam Ryszard
- Kiss Gabor
- Klay Jennifer Lynn
- Klein Carsten
- Klein Jochen
- Klein-Boesing Christian
- Klewin Sebastian
- Kluge Alexander
- Knichel Michael Linus
- Knospe Anders Garritt
- Kobayashi Taiyo
- Kobdaj Chinorat
- Kofarago Monika
- Kollegger Thorsten
- Kolozhvari Anatoly
- Kondratev Valerii
- Kondratyeva Natalia
- Kondratyuk Evgeny
- Konevskikh Artem
- Kopcik Michal
- Kour Mandeep
- Kouzinopoulos Charalampos
- Kovalenko Oleksandr
- Kovalenko Vladimir
- Kowalski Marek
- Koyithatta Meethaleveedu Greeshma
- Kralik Ivan
- Kravcakova Adela
- Kretz Matthias
- Krivda Marian
- Krizek Filip
- Kryshen Evgeny
- Krzewicki Mikolaj
- Kubera Andrew Michael
- Kucera Vit
- Kuhn Christian Claude
- Kuijer Paulus Gerardus
- Kumar Ajay
- Kumar Jitendra
- Kumar Shyam
- Kurashvili Podist
- Kurepin Alexander
- Kurepin Alexey
- Kuryakin Alexey
- Kweon Min Jung
- Kwon Youngil
- La Pointe Sarah Louise
- La Rocca Paola
- Ladron De Guevara Pedro
- Lagana Fernandes Caio
- Lakomov Igor
- Langoy Rune
- Lara Martinez Camilo Ernesto
- Lardeux Antoine Xavier
- Lattuca Alessandra
- Laudi Elisa
- Lea Ramona
- Leardini Lucia
- Lee Graham Richard
- Lee Seongjoo
- Lehas Fatiha
- Lemmon Roy Crawford
- Lenti Vito
- Leogrande Emilia
- Leon Monzon Ildefonso
- Leon Vargas Hermes
- Leoncino Marco
- Levai Peter
- Li Shuang
- Li Xiaomei
- Lien Jorgen Andre
- Lietava Roman
- Lindal Svein
- Lindenstruth Volker
- Lippmann Christian
- Lisa Michael Annan
- Ljunggren Hans Martin
- Lodato Davide Francesco
- Loginov Vitaly
- Loizides Constantinos
- Lokesh Kumar
- Lonne Per-Ivar
- Lopez Torres Ernesto
- Lopez Xavier Bernard
- Lowe Andrew John
- Luettig Philipp Johannes
- Lunardon Marcello
- Luparello Grazia
- Maevskaya Alla
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- Yoon Jin Hee
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- Zhalov Mikhail
- Zhang Haitao
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- Zhang Yonghong
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- Zhigareva Natalia
- Zhou Daicui
- Zhou You
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- Zimmermann Markus Bernhard
- Zinovjev Gennady
- Zyzak Maksym
- Publication venue
- Publication date
- 14/09/2015
- Field of study
We present measurements of the azimuthal dependence of charged jet production in central and semi-central root s(NN) = 2.76 TeV Pb-Pb collisions with respect to the second harmonic event plane, quantified as nu(ch)(2) (jet). Jet finding is performed employing the anti-k(T) algorithm with a resolution parameter R = 0.2 using charged tracks from the ALICE tracking system. The contribution of the azimuthal anisotropy of the underlying event is taken into account event-by-event. The remaining (statistical) region-to-region fluctuations are removed on an ensemble basis by unfolding the jet spectra for different event plane orientations independently. Significant non-zero nu(ch)(2) (jet) is observed in semi-central collisions (30-50% centrality) for 20 <p(T)(ch) (jet) <90 GeV/c. The azimuthal dependence of the charged jet production is similar to the dependence observed for jets comprising both charged and neutral fragments, and compatible with measurements of the nu(2) of single charged particles at high p(T). Good agreement between the data and predictions from JEWEL, an event generator simulating parton shower evolution in the presence of a dense QCD medium, is found in semi-central collisions. (C) 2015 CERN for the benefit of the ALICE Collaboration. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).Peer reviewe
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