31 research outputs found
Peritoneal dialysis peritonitis by anaerobic pathogens: a retrospective case series
- Author
- A Davenport
- A Tzamaloukas
- B Piraino
- C-C Szeto
- Cheng-Chung Fang
- Chia-Ter Chao
- Chih-Kang Chiang
- Chung-Jen Yen
- DG Maki
- DP Kofteridis
- DY Yap
- F Schaefer
- G Kambhampati
- H Giamarellou
- H Hayashi
- Huei-Wen Chen
- Japanese Society of Chemotherapy Committee on guidelines for treatment of anaerobic infections
- Jenq-Wen Huang
- JR Ghali
- JT Ngo
- Kuan-Yu Hung
- L Blairon
- L Boyanova
- M Chonchol
- MD Sarap
- PK-T Li
- S Cigarrán
- S Mujais
- S Zelenitsky
- SE Wilson
- Szu-Ying Lee
- TT Ho
- W Keane
- Wei-Shun Yang
- Y Suzuki
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Recommended from our members
What do parents perceive are the barriers and facilitators to accessing psychological treatment for mental health problems in children and adolescents? A systematic review of qualitative and quantitative studies
- Author
- A Angold
- A Gulliver
- A Mukolo
- AC Gerdes
- AE Kazdin
- AE Kazdin
- AM Cauce
- AR Stiffman
- Cathy Creswell
- CB Wolk
- CM Brown
- D Logan
- D Moher
- DA Chavira
- Doireann O’Brien
- DS Pine
- E Berger-Jenkins
- E Boulter
- E Cohen
- E Girio-Herrera
- GB Hickson
- GS Ginsburg
- GV Polanczyk
- H Bradby
- H Klasen
- IB Thurston
- IJ Flink
- J Guzder
- J Larson
- K Sayal
- K Sayal
- K Sayal
- KA Collins
- Kate Harvey
- KM Boydell
- KR Merikangas
- LJ Woodward
- LS Meredith
- Lydia Smith
- M Dixon-Woods
- M Gonçalves
- M Knapp
- M Yeh
- M Zwaanswijk
- MA Lindsey
- Magdalena Baranowska
- MD Harwood
- MD Pullmann
- ME Harrison
- ME Pailler
- MG Sawyer
- MJ Briggs-Gowan
- MM McKay
- MN Pavuluri
- MS Gould
- MV Chapman
- NA Fineberg
- P Cohen
- P Messent
- PC Gronholm
- PL Owens
- R Bussing
- R Bussing
- R Dempster
- R Layard
- R Shivram
- R Thompson
- RC Kessler
- RM Semansky
- S dosReis
- SE Teagle
- SH Kataoka
- SM Stein
- T Crawford
- T Ho
- Tessa Reardon
- V Eapen
- VM Murry
- W Shun Wilson Cheng
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2017
- Field of study
A minority of children and adolescents with mental health problems access treatment. The reasons for poor rates of treatment access are not well understood. As parents are a key gatekeeper to treatment access, it is important to establish parents’ views of barriers/facilitators to accessing treatment. The aims of this study are to synthesise findings from qualitative and quantitative studies that report parents’ perceptions of barriers/facilitators to accessing treatment for mental health problems in children/adolescents. A systematic review and narrative synthesis were conducted. Forty-four studies were included in the review and were assessed in detail. Parental perceived barriers/facilitators relating to (1) systemic/structural issues; (2) views and attitudes towards services and treatment; (3) knowledge and understanding of mental health problems and the help-seeking process; and (4) family circumstances were identified. Findings highlight avenues for improving access to child mental health services, including increased provision that is free to service users and flexible to their needs, with opportunities to develop trusting, supportive relationships with professionals. Furthermore, interventions are required to improve parents’ identification of mental health problems, reduce stigma for parents, and increase awareness of how to access services
The United States COVID-19 Forecast Hub dataset
- Author
- Abbott Sam
- Abu-Mostafa Yaser
- Adee Madeline
- Adhikari Bijaya
- Adiga Aniruddha
- Arik Sercan O.
- Asplund John
- Ayer Turgay
- Baccam Prasith
- Baek Jackie
- Baer Thomas M.
- Ban Xuegang
- Bannur Nayana
- Barber Ryan
- Bathwal Rahil
- Baxter Arden
- Bejar Benjamín
- Belov Artur A.
- Ben-Nun Michal
- Bennouna Amine
- Berlin Abraham
- Bertsimas Dimitris
- Bhatia Sangeeta
- Bian Jiang
- Biegel Hannah
- Bien Jacob
- Biggerstaff Matthew
- Bosch Jurgen
- Bosse Nikos I.
- Bouardi Hamza Tazi
- Bracher Johannes
- Brennen Andrea
- Brenner Michael
- Brooks Logan
- Budzinski Jozef
- Burant John C.
- Cao Duy
- Cao Wei
- Castro Lauren
- Cavany Sean
- Cegan Jeffrey C.
- Celi Leo A.
- Chang Nicholas A.
- Chattopadhyay Ishanu
- Chen Jinghui
- Chen Samuel
- Chen YangQuan
- Chen Ye
- Chen Yixian
- Chhatwal Jagpreet
- Chiang Wen-Hao
- Chinazzi Matteo
- Chintanippu Krishna
- Chitta Pavan
- Cho Jae H.
- Choirat Christine
- Chow Carson C.
- Coram Marc
- Cornell Matthew
- Corsetti Sabrina M.
- Cramer Estee Y.
- Cui Jiaming
- Dahan Maytal
- Dalgic Ozden O.
- Davis Jessica T.
- DesRoches David
- Dettwiller Ian D.
- Deva Ayush
- Drake John M.
- Dusenberry Mike
- Edwards Jessie K.
- Eisenberg Marisa C.
- England William P.
- Epshteyn Arkady
- Erickson Anne
- España Guido
- Fairchild Geoffrey
- Falb Karl
- Faraone Stephen V.
- Farias Vivek
- Farthing Matthew W.
- Ferres Juan Lavista
- Flahault Antoine
- Fong Chung-Yan
- Forli Pedro
- Fox Spencer
- Funk Sebastian
- Gaikedu Emmanuela
- Gaither Kelly
- Galasso Joseph
- Gandhi Parth D.
- Gao Junyi
- Gao Lei
- Gao Liyao
- Gao Zhifeng
- Gardner Lauren
- George Glover E.
- Georgescu Andreea
- Gerding Aaron
- Gerkin Richard C.
- Gibson Graham Casey
- Glass Lucas
- Gneiting Tilmann
- Goel Sumit
- Gowda Jethin
- Grantz Kyra H.
- Green Alden
- Gu Quanquan
- Gu Youyang
- Gu Zhiling
- Guertin Stephanie L.
- Guo Lihong
- Gurung Heidi L.
- Hamory Bruce
- Hay Simon
- Hellewell Joel
- Hess Jonathan
- Hill Alison L.
- Hlavacek William
- Ho Lam
- Hong Qi-Jun
- House Katie
- Hu Addison J.
- Huang Yi
- Huang Yitao
- Huang Yuxin
- Hulme-Lowe Christopher
- Hulse Juan Dent
- Hunter Robert H.
- Hurt Benjamin
- Hussain Fazle
- Huynh Huong
- Ibrahim Mark
- Ivy Julie S.
- Jadbabaie Ali
- Jahja Maria
- Jain Chaman
- Jain Chandini
- Jain Sansiddh
- Jayawardena Dasuni
- Jin Qixuan
- Jin Xiaoyong
- Jivane Viresh
- Jo Areum
- Jo HyeongChan
- Johansson Michael A.
- Joshi Keya
- Kalantari Rahi
- Kaminsky Joshua
- Kaminsky Kathryn
- Kanal Elli
- Kanji Abdul Hannan
- Karimzadeh Morteza
- Karlen Dean
- Keegan Lindsay T.
- Keskinocak Pinar
- Khan Zeina
- Khandelwal Ayush
- Khurana Ankita
- Kim Juhyun
- Kim Myungjin
- Kinsey Matt
- Klein Ellen
- Koyluoglu Ugur
- Kraus Andrea
- Kraus David
- Krymova Ekaterina
- Kulkarni Mihir
- Kulkarni Pranav
- Kumar Ajay
- Kyriakides Christina
- Lachmann Michael
- Lacroix Timothee
- Ladd Mary A.
- Lafferty Brandon
- Lakhani Anshul
- Lami Omar Skali
- Lauer Stephen A.
- Le Khoa
- Le Long T.
- Le Matthew
- Lee Elizabeth C.
- Lee Gavin
- Lega Joceline
- Leis Helen
- Lemaitre Joseph C.
- Lessler Justin
- Levi Retsef
- Lewis Bryan
- Li Chaozhuo
- Li Chun-Liang
- Li Michael L.
- Li Xinyi
- Liao Jason
- Lim Steve
- Lin Yen Ting
- Linas Benjamin P.
- Linkov Igor
- Liu Tie-Yan
- Lopez Velma K.
- Lu Guoqing
- Lucas Benjamin
- Lushtak Samuel M.
- Ma Yian
- Mallela Abhishek
- Manetti Elisa
- Mann Ethan
- Marathe Madhav
- Marshall Maximilian
- Martin Emily T.
- Mayo Michael L.
- Mayorga Maria E.
- McAndrew Thomas
- McCauley Ella
- McConnell Steve
- McDonald Daniel
- Meakin Sophie R.
- Mehrotra Prakhar
- Mele Jessica
- Meredith Hannah R.
- Merugu Srujana
- Meyers Lauren Ancel
- Michaud Isaac
- Miller Ely
- Milliken John
- Mody Vidhi
- Mody Vrushti
- Mohler George
- Moloney Michael
- Moore Sean
- Morgan James
- Morley Christopher P.
- Mu Kunpeng
- Mueller Peter
- Mullany Luke C.
- Murray Chris
- Myers Robert L.
- Mühlemann Anja
- Nagraj V. P.
- Namigai Kristen
- Narasimhan Balasubramanian
- Ndong David Nze
- Neumann Jacob
- Ngo Thoai
- Nickel Maximilian
- Niemi Jarad
- Nirgudkar Ninad
- Nixon Kristen
- Nouvellet Pierre
- Obozinski Guillaume
- Oidtman Rachel
- Oruc Buse Eylul
- Osthus Dave
- Ozcan Gokce
- O’Dea Eamon B.
- Pagano Robert
- Panaggio Mark J.
- Parno Matthew D.
- Pasumarty Sujitha
- Peddireddy Akhil Sai
- Penna Nicolas D.
- Perakis Georgia
- Perez-Saez Javier
- Perkins Alex
- Pfeiffer Ruth
- Pfister Tomas
- Pigott David
- Piontti Ana Pastore y
- Piriya Matthew
- Piwonka Noah
- Politsch Collin
- Popken Max
- Porebski Przemyslaw
- Posner Richard
- Prakash B. Aditya
- Qian Cheng
- Rainwater-Lovett Kaitlin
- Rajanala Samyak
- Raval Alpan
- Ravi Matt
- Ray Evan L.
- Reich Nicholas G.
- Reich Nicholas G.
- Reiner Robert C.
- Riley Pete
- Riley Steven
- Rivadeneira Alvaro J. Castro
- Rodríguez Alexander
- Romberg Justin
- Rosenstrom Erik T.
- Rowland Michael A.
- Rumack Aaron
- Sagun Levent
- Salekin Asif
- Sarker Arnab
- Schrader Chris
- Schwarz Tom
- Scott James G.
- Sen Pei
- Serban Nicoleta
- Shah Apurv
- Shah Devavrat
- Shah Sam
- Shakhnovich Elizabeth
- Shaman Jeffrey
- Sharma Rakshith
- Sheldon Daniel
- Sherratt Katharine
- Shi Yunfeng
- Shin Lauren
- Shingi Siddhant
- Shrivastav Monika
- Siegel Daniel
- Simon Noah
- Singhvi Divya
- Sinha Deeksha
- Sinha Rajarishi
- Slayton Rachel B.
- Smith Claire P.
- Soni Saksham
- Soohoo Connor
- Spaeder Jeffrey
- Spantidakis Ioannis
- Spatz Ryan
- Srivastava Ajitesh
- Stage Steven A.
- Stark Ariane
- Stiefeling Chris
- Suchoski Bradley T.
- Sumner Timothy
- Sun Jimeng
- Sun Tao
- Sundar Saketh
- Swann Julie L.
- Tabassum Anika
- Tallaksen Katharine
- Tec Mauricio
- Thanou Dorina
- Thayaparan Leann
- Tibshirani Rob
- Tibshirani Ryan J.
- Tirumala Kushal
- Tiwari Avtansh
- Tomar Vishal
- Tran Quoc
- Truelove Shaun A.
- Trump Benjamin D.
- Tsai Thomas
- Tseng Albert
- Tsiourvas Asterios
- Turner Stephen D.
- Turtle James
- US COVID-19 Forecast Hub Consortium
- Vahedi Behzad
- Van Bussel Frank
- van de Walle Axel
- Varadarajan Vignesh
- Venkatramanan Srinivasan
- Ventura Valerie
- Vespignani Alessandro
- Vytheeswaran Jagath
- Walker Jo W.
- Walraven Robert
- Wang Christopher
- Wang Dongdong
- Wang Dongliang
- Wang Guannan
- Wang Lijing
- Wang Lily
- Wang Lingxiao
- Wang Liqiang
- Wang Qinxia
- Wang Yijin
- Wang Yu-Xiang
- Wang Yuanjia
- Wang Yueying
- Wang Zhongying
- Wasserman Larry
- Wattanchit Nutcha
- Weisberg Shane
- White Jerome
- Wilde Joshua
- Wilkinson Barrie
- Wills Josh
- Wilson Austin
- Wilson Daniel
- Wilson Shelby
- Wolffram Daniel
- Wolfinger Russ
- Wong Alexander
- Woody Spencer
- Wu Dongxia
- Xiao Cao
- Xiao Jade
- Xie Jiajia
- Xie Shanghong
- Xie Xing
- Xiong Xinyue
- Xu Pan
- Xu Tianjian
- Yamana Teresa K.
- Yan Xifeng
- Yeluri Akshay
- Yeung Dit-Yan
- Yoder Nate
- Yogurtcu Osman N.
- Yoon Jinsung
- You Jialu
- Yu Rose
- Yu Shan
- Yurk Dominic
- Zeng Donglin
- Zhang Leyou
- Zhang Michael
- Zhang Shun
- Zhang Shunpu
- Zhang Weitong
- Zhang-James Yanli
- Zhao Yanting
- Zheng Andrew
- Zheng Shun
- Zhou Mingyuan
- Zimmerman Peter
- Zlokapa Alexander
- Zoraghein Hamidreza
- Zorn Martha W.
- Zou Difan
- Zou Zihang
- Publication venue
- Nature Research
- Publication date
- 17/08/2022
- Field of study
Academic researchers, government agencies, industry groups, and individuals have produced forecasts at an unprecedented scale during the COVID-19 pandemic. To leverage these forecasts, the United States Centers for Disease Control and Prevention (CDC) partnered with an academic research lab at the University of Massachusetts Amherst to create the US COVID-19 Forecast Hub. Launched in April 2020, the Forecast Hub is a dataset with point and probabilistic forecasts of incident cases, incident hospitalizations, incident deaths, and cumulative deaths due to COVID-19 at county, state, and national, levels in the United States. Included forecasts represent a variety of modeling approaches, data sources, and assumptions regarding the spread of COVID-19. The goal of this dataset is to establish a standardized and comparable set of short-term forecasts from modeling teams. These data can be used to develop ensemble models, communicate forecasts to the public, create visualizations, compare models, and inform policies regarding COVID-19 mitigation. These open-source data are available via download from GitHub, through an online API, and through R packages
Large expert-curated database for benchmarking document similarity detection in biomedical literature search
- Author
- Aanei Carmen M.
- Abid Muhammad B.
- Abramowitz Matthew K.
- Abu-Zaid Ahmed
- Adamo Vincenzo
- Adeyemo Adebolajo A.
- Afnan Masoud
- Agarabi Cyrus
- Aggelidou Maria
- Ahmad Haroon
- Ahmad Rafi
- Aizat Wan M.
- Ajani Penelope A.
- Akinwumi Sayo A.
- Al-Farha Abd A.
- Al-Lawama Manar
- Al-Owaifeer Adi M.
- Al-Riyami Arwa Z.
- Alanio Alexandre
- Alaux Cedric
- Albery Gregory F.
- Albiol Joan
- Albrecht Dirk R.
- Albuquerque Lucia G.
- Alhowimel Ahmed
- Ali Junaid
- Alimba C.G.
- Allardyce Judith
- Almeida Gabriel M.F.
- Alonso-Caneiro David
- Alper Ozgul M.
- Alshehri Mansour
- Alsuhaibani Mohammed
- Alzghari Saeed K.
- Amer Said E.D.R.
- Amir Shimon
- Amiya Eisuke
- Ammerman Brooke A.
- Amorim Rogerio M.
- An Qianli
- Anazodo Udunna C.
- Andersen Stig U.
- Andersen Vibeke
- Angus Kathryn
- Anikin Andrey
- Aplin John D.
- Argyropoulos Christos
- Armitage Charles
- Asaduzzaman Muhammad
- Asady Hadi
- Ascher David B.
- Ashry Mohamed
- Asmann Yan W.
- Assaeed Abdulaziz M.
- Atack John M.
- Atanasov Atanas G.
- Atchison David A.
- Atkins Gerald J.
- Atlas Lauren
- Ato Dai
- Avery Simon V.
- Avillach Paul
- Azubuike Samuel O.
- Baade Peter D.
- Bach-Mortensen Anders
- Backman Lars
- Badie Christophe
- Bae Taeok
- Bagloee Saeed Asadi
- Bai Xiaoyong
- Baier Dirk
- Bail Kasia
- Baines Rebecca L.
- Baker Chris I.
- Bakkach Joaira
- Baldi Alfonso
- Ball Elizabeth
- Ballantyne Maghan
- Baltiansky Lior
- Ban Bo
- Bannon Ross
- Bansal Abhisheka
- Bar Ido
- Bardot Olivier
- Barnett Adrian G.
- Barraud Pierre
- Bartas Martin
- Basharat Zarrin
- Basner Mathias
- Bathelt Joe
- Batra Jyotsna
- Baumert Philipp
- Bazanova O.M.
- Beale Andrew
- Beck Charles R.
- Beck Jill
- Becker Daniel
- Beddoe Travis
- Belachew Kiflemariam Y.
- Bell Melanie L.
- Ben-Nafa Walid
- Benezeth Yannick
- Bengtsson-Palme Johan
- Benkeser David
- Berbesque Colette
- Berezikov Eugene
- Bergsland Niels
- Berners-Price Sue
- Bernhardt Peter
- Bernier Meghan L.
- Berrevoet Frederik
- Berry Edward
- Berthold Maximilian
- Bessa Theolis B.
- Beyene Tariku J.
- Bhardwaj Vivek
- Biedermann Peter H.W.
- Bijleveld Erik
- Billington Craig
- Binder Karin
- Birch John
- Bittner Florian
- Bitzer Michael
- Black Emma
- Blakely Randy D.
- Blanchard Adam M.
- Blancher Antoine
- Blanck Oliver
- Bland Nicholas S.
- Blankstein Ron
- Blaskovich Mark A.T.
- Bleackley Mark
- Blombach Fabian
- Blum Robert
- Boah Michael
- Boakye Dominic W.
- Bodagh Neil
- Boehme Karen A.
- Boelaert Marleen
- Bogdanos Dimitrios
- Bonatsos Vasileios
- Bonvin A.M.J.J.
- Boon Michele H.
- Borges Paulo
- Bosch Carles
- Bosch Oliver
- Bouboulis George
- Boudreau Shellie A.
- Bourgoin Thierry
- Bourke Emer
- Bouvard Daniel
- Boykin Laura M.
- Br\ufchl Albert
- Bradley Graeme
- Bradshaw William
- Bramoweth Adam D.
- Brand Thomas
- Braubach Oliver
- Braun Daniel
- Braun R. J.
- Brenneisen Peter
- Bridges Kristina M.
- Bromfield Elizabeth
- Brooks Anastasia
- Brown James A.L.
- Brown Joshua
- Brown Peter
- Browngardt Christopher
- Brownlie Jeremy
- Brox-Ponce Josue
- Brunetti Arturo
- Bukowy-Bieryllo Zuzanna
- Bul Kim C.M.
- Bull James A.
- Bullen Benjamin
- Burt Austin
- Burton Kathryn J.
- Bush Stephen J.
- Butkowski Eugene G.
- Butler Lisa M.
- Byrareddy Siddappa N.
- Byrne Hugh J.
- Cabantous Stephanie
- Cai Yufeng
- Calabr\uf2 Giovanna E.
- Calatayud Sara
- Callahan Tiffany J.
- Campana Luca G.
- Campbell Matthew
- Candal Eva
- Canham Colin D.
- Cao Bing
- Cao Zanxia
- Cao Zehong
- Cardoso Pedro
- Carlson Kimberly
- Carninci Piero
- Carroll Grace
- Carter Dee
- Carvajal Richard
- Cascella Marco
- Casillas S\uf2nia
- Castelvetro Valter
- Caswell Patrick T.
- Catry Thibault
- Cavalli Giacomo
- Cernava Tomislav
- Cerovsky Vaclav
- Ch\ue1vez-Fumagalli Miguel A.
- Chacko George
- Chagoyen Monica
- Chakraborty Sayan
- Chalmers Kelsey
- Chan Sherwin S.
- Chandrasekaran Arun R.
- Chang Shun C.
- Chang Wei
- Chao Fengqing
- Chao Jie
- Charrier Elisabeth E.
- Chatterjee Pranab
- Chatzitheochari Stella
- Che Zhengping
- Chen Andrew T.Y.
- Chen Branson
- Chen Chang-Er
- Chen Chang-Shi
- Chen Dong F.
- Chen Haimin
- Chen Hao
- Chen He
- Chen Huaming
- Chen Hui
- Chen Jui-Tung
- Chen Liming
- Chen Xiaoyin
- Chen Xin
- Chen Yi-Chun
- Chen Yinglong
- Chen Youning
- Chen Yu-Chih
- Chen Zhao
- Cheng Changxiu
- Cheng Jianlin
- Cheng Shuiqin
- Chenguang [NO FIRST NAME IN SCOPUS]
- Cheung Johnny T.K.
- Chhatriwalla Adnan K.
- Chikowe Ibrahim
- Chinapaw Mai
- Chinopoulos Christos
- Cho William C.S.
- Choi Jane R.
- Choi Youngrok
- Chong Lillian
- Chowdhury Debashish
- Chowdhury Mohiuddin A.K.
- Christensen Martin R.
- Christoffersen Tore
- Chuang Trees-Juen
- Chung Hee-Jung
- Chwalibog Andre
- Ciresi A.
- Cobine Paul A.
- Cockcroft Shamshad
- Coelho Luis P.
- Colella Vito
- Collevatti Rosane G.
- Comel Jo\ue3o C.
- Conesa Ana
- Conway Aaron
- Cook Penny A.
- Cooke Robert S.C.
- Cooper David N.
- Cooper Jeffrey
- Coqueret Olivier
- Corea Enoka M.
- Cornejo Diego A.V.
- Cosacak Mehmet I.
- Cosse Cyril
- Costa Antonio
- Costa Bruno M.
- Costa Elisio
- Costa Vincent D.
- Cottini Marzia
- Coupland Carol
- Covington Natalie V.
- Crawford Stephanie Y.
- Cruz Aparecido D.
- Cu\uedv P\ue1raic O.
- Cuenda Ana
- Cui Huijuan
- Cui Qiang
- Cui Yanru
- Culver David C.
- Cunningham Catriona
- Cuypers Maarten
- Cyr Normand
- D\u27Angiulli Amedeo
- Dahms Tanya E.S.
- Dai Zhanwu
- Daigle France
- Dalgleish Raymond
- Dalrymple Brian P.
- Danchin Antoine
- Danielsen H\ue5vard E.
- Dao Myriam
- Darras S\ue9bastien
- Dauga Delphine
- Daulatabad Swapna V.
- Davidson Sean M.
- Day David A.
- de Keersmaecker Kim
- de Leeuw Frank-Erik
- de Maio Nicola
- Dean Lorraine T.
- Debrabant Birgit
- Degirmenci Volkan
- Del Tredici Andria L.
- Delahay Robin M.
- Delarocque Julien
- Demaison Luc
- Deng Zaian
- Denzel Martin S.
- Deschodt Mieke
- Devkota Hari P.
- Devkota Kiran
- Devos Lucie
- Devriendt Koenraad
- Dhar Aurup R.
- Dhariwal Raman
- Dhaval [NO FIRST NAME IN SCOPUS]
- Diao Jiajie
- Ding Jiandong
- Ding Ke-Feng
- Dings Ruud P.M.
- Diodato Daria
- Diouf Barthelemy
- Dixon Ray
- Dlamini S.V.
- Doan Lisa V.
- Dogan Yunus
- Domingues Helena S.
- Dong Kexian
- Dong X.C.
- Dong Zheng
- Donner Claudio F.
- Dono Marcos
- Doxey Andrew C.
- Dressick Walter
- Drevon Christian A.
- Dreyer Niklas
- Duan Huiling
- Ducho Christian
- Ducommun Bernard
- Dudley Kevin J.
- Duffey Maelle
- Dufies Maeva
- Duijf Pascal H.G.
- Dumaz Nicolas
- Dutt Avik
- Dwarakanath Bilikere S.
- Ebell Mark H.
- Echeverr\ueda Natalia
- Ecke Thorsten
- Eckweiler Denitsa
- Eerola Tuomas
- Effiong Andem
- Egea Luis G.
- Ehret Felix
- Eisenhardt Steffen
- Eixarch Elisenda
- Ekstrand Chelsea
- El-Adawy Hosny
- El-Esawi Mohamed A.
- El-Said Mohammed
- Elewa Yaser H.A.
- Elkum Naser
- Emmrich Julius V.
- Engel Michael S.
- Engel Nadja
- Epp Trevor
- Erickson Timothy B.
- Esfahlani Shabnam S.
- Eskelinen Eeva-Liisa
- Eskew Evan A.
- Esnakula Ashwini K.
- Eustace Alex J.
- Evangelou Evangelos
- Fairhead Michael
- Falk Sebastian
- Fallah Mazyar
- Falter-Wagner Christine M.
- Fan Dongsheng
- Fan Xiao
- Farber Debora B.
- Fardet Tanguy
- Farhoudi Ramin
- Faruk Mohammed
- Faville Marty J.
- Faye Martin
- Feghali Karine A.
- Feifei Shi
- Fejzo Marlena S.
- Feleke Berhanu E.
- Ferguson Trevor S.
- Fernandez-Fernandez Beatriz
- Fernandez-Triana Jose
- Festa Fernanda
- Feteira Antonio
- Feurer Thomas
- Feyerabend Frank
- Fierz Walter
- Filipp Fabian
- Flegel Willy A.
- Fleres Francesco
- Flood-Page Patrick
- Florio Tullio
- Foley Kieran G.
- Forano Evelyne
- Forsayeth John
- Foster Emma J.
- Foster Stephen
- Founou Luria L.
- Fox Simon A.
- Franks Steven J.
- Freitas Angela
- Frentiu Francesca D.
- Friebe Michael
- Frilander Mikko J.
- Fu Fan
- Fu Xinmiao
- Fujita Satoshi
- Furer Tzvi
- Furuta Saori
- Fuss Johannes
- Gabrielsen Mads
- Gadelkareem Rabea A.
- Gajda Maksymilian
- Galea Ian
- Galimov Evgeny
- Galluzzi Luca
- Gani Federica
- Ganpule Arvind P.
- Gao Jianzhao
- Gao Tian
- Gao Yibo
- Garc\ueda-Alix Antonio
- Garcia-Rivera Enid J.
- Garip Gulcan
- Gatchell Michael
- Gaullier Guillaume
- Gazdar Adi
- Gebremedhin [NO FIRST NAME IN SCOPUS]
- Gedye Kristene
- Gelfer Yael
- Gemmill Alison
- George Ronald B.
- Ghelardi Emilia
- Ghosh Sayantan
- Gianchecchi Elena
- Giganti Francesco
- Gill Martin R.
- Gilliham Matthew
- Giordano Maurizio
- Giunta Cecilia
- Gladue Douglas P.
- Gleason Joshua M.
- Gleeson Paul A.
- Gloyn Liz
- Gnasso Agostino
- Goarant Cyrille
- Gobet Ang\ue9lique
- Goggs Robert
- Gong Haipeng
- Gonz\ue1lezlez-Prendes Rayner
- Goodin Amie
- Goodyear Carl S.
- Gora Diop
- Gough Michael J.
- Gouil Quentin
- Govender Pragashnie
- Govinden Usha
- Goyal Ravinder
- Gr\ue9bert Th\ue9ophile
- Gr\ufcneberg Patrick
- Grabowski Piotr
- Graham Emily B.
- Graham Kathryn E.
- Grande-P\ue9rez Ana
- Graves Patricia M.
- Greene Garrett
- Greenwald Noah F.
- Greidanus Harm
- Greiff Victor
- Grey James
- Grice Darren
- Gridneva Zoya
- Grimm Dominik G.
- Groen Ewout J.N.
- Grothe Michel J.
- Gruber Jens
- Grunau Christoph
- Grundle D.S.
- Grybos Malgorzata
- Guerra-Mora Jos\ue9 R.
- Guerrero Fabricio
- Guignard L\ue9o
- Guisado J.L.
- Gumede Nicksy
- Gumulya Yosephine
- Guo Chengying
- Guo Xinyi
- Guo Yabin
- Gupta Himanshu
- Gurevich Vsevolod V.
- Gurney-Champion Oliver J.
- Gusev Oleg
- Guti\ue9rrez-Sacrist\ue1n Alba
- H\ufcttner Felix J.
- Habes Mohamad
- Hacker Elke
- Hackshaw Allan
- Haenssgen Marco J.
- Hage Steffen R.
- Hagen Guy
- Hahn Steven
- Hall Adam
- Hall Richard
- Haller Dagmar M.
- Hammerschmidt Sven
- Han Hyemin
- Han Jianwei
- Han Qian
- Han Renzhi
- Handfield Martin
- Hanson Jack
- Haore Gbaguidi
- Hapuarachchi Hapuarachchige C.
- Harder Timm
- Hardingham Jennifer E.
- Harper Paul
- Harrison Pille
- Hartmann Marcus D.
- Harvey David J.
- Hasler David
- Haston Scott
- He Shuonan
- Heck Michelle
- Heers Marcel
- Heffler Enrico
- Heijne Marloes
- Heinemann Stephanie
- Heinrich Michael
- Helanter\ue4 Heikki
- Herbelet Sandrine
- Hew Khe F.
- Higginbottom Daniel B.
- Higuchi Yohei
- Hilaire Cynthia St.
- Hilton Rachel
- Hiroi Noboru
- Hobbs Emma
- Hodzic Enisa
- Hoenner Xavier
- Hogg William E.
- Hogrebe Alexander
- Hojsgaard Diego
- Holgate Joan Y.
- Hone Andrew
- Hongoh Yuichi
- Honjo Ken
- Horbar Jeffrey
- Hori Hikaru
- Hu Guoku
- Hu Pingzhao
- Huang Ancheng
- Huang Guangqun
- Huang Zhengping
- Huber Heinz P.
- Huber Michael
- Hueso Luis E.
- Huirne Judith
- Hulse-Kemp Amanda M.
- Hunter Kylie E.
- Hurt Lisa
- Idborg Helena
- Ide Kazuki
- Ijzerman Adriaan P.
- Ikeo Kazuho
- Ikonomopoulou Maria P.
- Ingley Evan
- Iskander-Rizk Sophinese
- Iyer Lavanya M.
- J\ue9gousse Clara
- Jahan Yasmin
- Jakeman Philip M.
- James Ameh S.
- Janga Sarath C.
- Janzen Thijs
- Jayaraman Jayakumar
- Jean-Quartier Claire
- Jeltsch Albert
- Jensen Arne
- Jeon Sang-Min
- Jesus Carlos
- Jeurissen Patrick
- Jia Hong
- Jia Husen
- Jia Shuqin
- Jia Yangyang
- Jian Gao
- Jiang Fan
- Jiang Jianping
- Jiang Xingyu
- Jibb Lindsay A.
- Jin Yi
- Jo Daehyun
- Joel Emmanuel
- Joffroy Bastian
- Johnson Andrew M.
- Johnson Daniel M.
- Johnston Marie
- Jongen Stefan
- Jonscher Karen R.
- Jorens Philippe G.
- Jorgensen Jens O.L.
- Josse Claire
- Joubert Johan W.
- Jung Sin-Ho
- Junior Antonio M.
- Jurman Giuseppe
- Jutzeler Catherine
- Kabra Dhiraj
- Kahan Thomas
- Kaiser Stefan
- Kalatzis Panagiotis
- Kamagata Koji
- Kamboj Sunjeev K.
- Kambondo George
- Kamiya Haruyuki
- Kane Nolan C.
- Kang Yong-Kook
- Kanj Souha S.
- Karamanos Yannis
- Karim Masud
- Karmakar Chandan
- Karnati Priyanka
- Karp Natasha A.
- Karsay Kathrin
- Kasian Olga
- Kauppila Joonas H.
- Kaur Harsheen
- Kaya Cihan
- Kaye Linda K.
- Ke An
- Keitel Anne
- Kelly Daniel
- Kelly Ryan
- Kelly Sarah
- Kelly Shona
- Kempe Andreas
- Kenna Ralph
- Kennedy Jonathan
- Keown Jeremy R.
- Kersten Birgit
- Khalaf Roy A.
- Khalid Javaria M.
- Khan Murad M.
- Khatlani T.
- Kheir Fayez
- Khider Tarig
- Khoo Chin M.
- Khwaja Nyil
- Kichatova V.S.
- Kickert Rob
- Kidibule Peter E.
- Kieselmann Jennifer P.
- Kievit Rogier A.
- Kijanka Gregor S.
- Kim Hyeon J.
- Kim Yong-Min
- King Sarah R.B.
- Kinyanjui Timothy
- Kiraǧ N\ufckhet
- Kish J.K.
- Kitazawa Takeshi
- Kiyani Musa
- Klein Reinhild
- Klempnauer Karl-Heinz
- Kleppe Andreas
- Klump Hannes
- Kluz Tomasz
- Knox Paul
- Kobayashi Tatsuya
- Kobold Sebastian
- Koch Karl-Wilhelm
- Kohanbash Gary
- Kohls Gregor
- Kohonen-Corish Maija R.J.
- Koleva-Kolarova Rositsa G.
- Kong Xiangpeng
- Konkle-Parker Deborah
- Korpela Kalevi M.
- Kosanic Sasha
- Kostrikis Leondios G.
- Koutoukidis Dimitrios A.
- Kovesi Tom
- Kraiczy Peter
- Kramer Paul
- Kraschnewski Jennifer L.
- Kratz Harald
- Krause G\ufcnter
- Krebsbach Paul H.
- Kristensen S\uf8ren R.
- Kristiansson Erik
- Kueberuwa Gray
- Kugler Jan-Michael
- Kulkarni Ameya
- Kumar Addanki P.
- Kumar Dilip
- Kumar Gyanendra
- Kumar Narendra
- Kumar Nitin
- Kumari Prerna
- Kunimatsu Akira
- Kurdak Hatice
- Kurgan Lukasz
- Kurniawan Nicholas A.
- Kwon Young D.
- Labutin Dmitry
- Lachat Carl
- Lacy-Colson Jon
- Lagisz Malgorzata
- Lai Hei M.
- Laky Brenda
- Lalaouna David
- Lamberts Aniek
- Lammerding Jan
- Lange Matthias
- Lanza Giuseppe
- Larrosa Mar
- Laslett Andrew L.
- Latif Asam
- Lau Colleen L.
- Lauschke Volker M.
- Laverman Gozewijn D.
- Lazo-Langner Alejandro
- Le Thuc D.
- Leclair Elizabeth E.
- Leclercq Guy
- Lee Kyung-Woo
- Lee Ming-Yih
- Lee Moon-Soo
- Lee Senhong
- Leem Jung W.
- Leightley Daniel
- Leite Andreia
- Lercher Lukas
- Lewis James S.
- Li Bingling
- Li Genyuan
- Li Jian
- Li Jiansheng
- Li Jiuyong
- Li Maoteng
- Li Qingchun
- Li Tangliang
- Li Ying
- Li Yongzhe
- Li You
- Li Zhixiu
- Liang Dai
- Liang Huakang
- Liang Shide
- Liao Wei-Ting
- Liao Zheng-Yin
- Lidbury Brett A.
- Lieb Klaus
- Liehr Thomas
- Liew Alan W.C.
- Lim Chinten J.
- Lim Renly
- Lim Yau Y.
- Lima Luiz R.A.
- Lin Jessica
- Lin Li
- Lin Michael Z.
- Lindsey Merry L.
- Line Paul-Dag
- Ling Tong
- Linn Sabrina N.
- Litfin Thomas
- Liu Dengcai
- Liu Enwu
- Liu Fang
- Liu Fengbin
- Liu Haiyan
- Liu Hongde
- Liu Siqi
- Liu Xiaodong
- Liu Yu-Peng
- Liu Yuchen
- Liu Zhonghua
- Liusuo Wang
- Lizer J.
- Lloyd Vett K.
- Lo Te-Wen
- Lobreglio Giambattista
- Locci Emanuela
- Loft Nikolai D.
- Loidl Josef
- Lopez-Escamez Jose A.
- Lopez-Ruiz Francisco J.
- Lorenzen Johan
- Lorkowski Stefan
- Lovell Nigel H.
- Lowies Cher
- Lu Cheng
- Lu Hua
- Lu Jin-Jian
- Lu Qiang
- Lu Wei
- Lu Yao
- Lu Zhiyong
- Luengo Gustavo S.
- Lum Fok M.
- Lund Bjarte A.
- Lundh Lars-Gunnar
- Luo Hang
- Lussier Alexandre A.
- Luu Andreas M.
- Lygirou Vasiliki
- Lynch Iseult
- Lysy Philippe A.
- Lyu Ran
- Ma Chuang
- Ma Lan
- Ma Liping
- Ma Lisong
- Ma Ruiyan
- Ma Wujun
- Mabb Angela
- Machhi Jatin
- Mack Heather G.
- Mackey David A.
- Macleod Angus
- Macwan Isaac
- Madala Hanumantha R.
- Madani Nima
- Mahato Ajay K.
- Mahavadi Poornima
- Mahdavi S.R.
- Maher Pamela
- Maher Toby
- Mai Zhi-Ming
- Maibach Edward W.
- Maity Sankar N.
- Majeed Haroon
- Major Rupert W.
- Makowiecki Kalina
- Malgrange Brigitte
- Mali Samira
- Mallinson Daniel J.
- Mallis Panagiotis
- Mamoulakis Charalampos
- Mangoni Arduino A.
- Manke Thomas
- Manstead Antony S.R.
- Mantalaris Athanasios
- Mao Wenzhi
- Marchbank Kevin J.
- Margelyte Ruta
- Maria Caracausi
- Marinello Francesco
- Markonis Y.
- Marsal Jan
- Marschalek Rolf
- Marschall H. U.
- Marsili Luca
- Mart\uedn Carmen S.
- Martin Adam
- Martin Francis L.
- Martinez-Raga Jose
- Martinez-Salas Encarnacion
- Martinez-Sobrido Luis
- Martis Elvis
- Marvin-Dowle Katie
- Marzocchi Ugo
- Mason Leanda D.
- Mather Diane E.
- Mathieu Daniel
- Matsui Yoichi
- Mavoa Suzanne
- Maza Elie
- McCrum Christopher
- McCutcheon James E.
- McGarrigle Christine A.
- McKay Gareth J.
- McMillan Brian
- McMillan Nigel
- McWilliams Lorna
- Meads Catherine
- Medina Loreta
- Megersa Moa
- Mendes Caetano S.M.
- Menichetti Julia
- Mercieca-Bebber Rebecca
- Meresh Edwin
- Merideth Ben
- Merino-Plaza Maria J.
- Merlaen Britt
- Merrick B. Alex
- Meseko Clement
- Messina Rossella
- Metzger Dennis W.
- Meule Adrian
- Meunier Frederic A.
- Michaelis Martin
- Micheau Olivier
- Middelveen Marianne
- Miele Adriana E.
- Mier Pablo
- Mihara Hisaaki
- Miller Jack J.
- Min Rogier
- Minde David-Paul M.
- Minges Alexander
- Mintz Eric M.
- Miotla Pawel
- Mishra Anand K.
- Mishra Eleanor
- Mishra Virendra R.
- Mitchell Kate M.
- Mizukami Takuo
- Moal Iain
- Moalic Yann
- Mohapatra D.P.
- Mohebbi Alireza
- Molari Massimiliano
- Molleman Lucas
- Mondal Saiful R.
- Montagutelli Xavier
- Monteiro Antonia
- Montes Matthieu
- Moore Matthew D.
- Moores Carly
- Moran John V.
- Morcillo Esteban
- Morozov Sergey Y.
- Morrice Nicola
- Mort Matthew
- Moskalensky Alexander E.
- Moss W.N.
- Mota Jorge
- Moultos Othonas A.
- Moyer Robert
- Mozaheb Zahra
- Muhammad Junaid
- Mukherjee Maheswari
- Murai Noriyuki
- Murphy Denis J.
- Murphy Susan K.
- Murray Shauna A.
- Musinguzi Conrad
- Muth Thilo
- Muyaya Ley
- Naganawa Shinji
- Nagler Katja
- Nakayama Kazuhiko
- Nammi Srinivas
- Nandakumar Kutty S.
- Nandhakumar Amar
- Nanou Afroditi
- Naqash Amreen
- Narayan Edward
- Nasios Grigorios
- Natoli Roman M.
- Navaratnarajah [NO FIRST NAME IN SCOPUS]
- Navarin Nicol\uf2
- Negera Edessa
- Neumann Philipp-Alexander
- Ng Grace
- Ng Sheryl H.X.
- Nguyen Frederique
- Nguyen Joe T.
- Nguyen Thi T.H.
- Ni Duan
- Nicol Christine
- Nicoletti Rosario
- Nida [NO FIRST NAME IN SCOPUS]
- Nie Jiyun
- Nie Yingjiu
- Niehof Monika
- Niemeyer Frank
- Nilsen Erlend B.
- Nilsson Henrik
- Nixon Brett
- Nobile Clarissa J.
- Nolan Fiona
- Nolet Philippe
- Nord\ue9n Rickard
- Nordberg Ana
- Norris Adam D.
- Notcovich Shirli
- Nowicki Jessica P.
- Nwaiwu Ogueri
- O\u27Mahony Margaret
- O\u27Toole Ronan
- Obeidat Monther
- Ogami Koichi
- Oh Deog-Hwan
- Ohgami Robert S.
- Ohlsson Sophie
- Ohst Barnabas
- Ohtomo Toshihiko
- Olatunbosun Oluremi
- Oldenmenger Wendy H.
- Ollivier Quinn R.
- Olofsson Per
- Olova Nelly
- Olszewski Pawel
- Olumayede Emmanuel
- Onzima Robert
- Orme Mark W.
- Ortiz Alberto
- Osses Dani\uebl F.
- Oster Henrik
- Ostrikov Kostya
- Otto Siegmar
- Ou Jianhong
- Outeiro Tiago F.
- Ouyang Songying
- Owais Mohammed
- Pace-Asciak Pia
- Paganoni Sabrina
- Page Andrew
- Pallebage-Gamarallage Menuka
- Palm Christoph
- Palma Jose-Alberto
- Pan Chih-Long
- Pan Zihang
- Panthee Suresh
- Panwar Ajay
- Paradies Yin
- Parchi Piero
- Park Caroline
- Park Charny
- Park Dong I.
- Park Seyoung
- Parsons Jerod R.
- Parsons Michael H.
- Parsons Nick
- Pascal Pigny
- Paterson Russell
- Patil Chandrashekhar D.
- Patterson Chris
- Paul Elisabeth
- Pearce Simon P.
- Pearson James A.
- Peckham Michelle
- Pedemonte Nicoletta
- Pedro Sansoa A.
- Peifer Mark
- Pelkonen Tuula
- Pelleri Maria C.
- Pellizzon Michael A.
- Penagos-Tabaree Felipe
- Peng Xiangda
- Peng Yousong
- Perco Paul
- Pereira Joana L.
- Peres Marco A.
- Perry Samuel R.
- Peter Jessica
- Peterson Brent M.
- Petrelli M.
- Pezzuolo Andrea
- Pheko Mpho
- Pianosi Paolo T.
- Pichugin Alexander
- Pinto Carlos J.C.
- Pinto Ines M.
- Pinto Karina A.
- Pinzi Valentina
- Piotrowski Marcin
- Piovesan Allison
- Plantinga Arnoud
- Plevris John N.
- Pluess Michael
- Podolsky Illya M.
- Pollesello Piero
- Polz Martin
- Ponti Giovanna
- Popoola Segun I.
- Porcelli Piero
- Portilla Maribel
- Portillo M.C.
- Pourret Olivier
- Pozdnyakov Ilya
- Prajapati Anilkumar S.
- Pranata Raymond
- Prescott Julie
- Pridans Clare
- Prieto Daniel
- Prince Martin
- Pritchard Antonia L.
- Psaroulaki Anna
- Pujala Ravi K.
- Pulia Michael
- Pulido-Arjona Leonardo
- Pullan Wayne
- Pusch Stefan
- Qi Dongchen
- Qi Peng-Fei
- Qi Xingshun
- Qian Siyu
- Qin Lei
- Quinn Gwendolyn P.
- Quinn Terence J.
- Rafe Ali
- Rafiq Muhammad
- Raghava Gajendra P.S.
- Rahimi Farid
- Rahman Proton
- Rahman Shaifur
- Rai Nayanjot K.
- Raikou Vaia D.
- Raman Ayush
- Ramula Satu
- Ranft Andreas
- Raote Ishier
- Rappsilber Juri
- Rassaf Tienush
- Raucher-Ch\ue9n\ue9 [NO FIRST NAME IN SCOPUS]
- Rawski Rafal
- Ray Asit
- Raza Ali
- Razak Lubna A.
- Rebl Henrike
- Reddan Tristan
- Refai Osama
- Refardt Julie
- Regan Tim
- Rehfeldt Florian
- Reiling Jan H.
- Remacle Claire
- Reschke Cristina R.
- Rezaei Mohsen
- Rhodes Johanna
- Ricciardi Walter
- Richa Tambi
- Richardson Mark F.
- Riddick Eric W.
- Riess Olaf
- Ritter Uwe
- Riva Giuseppe
- Roach Neil W.
- Roberts David D.
- Roberts Nicola J.
- Robinson K.R.
- Robles Guillermo
- Rodrigues Tiago
- Rodriguez Cesar
- Roislien Jo
- Roobol Monique J.
- Ross Kehinde
- Ross Stephanie A.
- Rossoni Luca
- Rotge Jean-Yves
- Rouet Romain
- Rovas Alexandros
- Rowe Alexandra
- Rowe Anna D.
- Rudolf Kevin
- Ruepp Andreas
- Rusch Peter
- Rust Petra
- S\uf6relius Karl
- Saad Sonia
- Sabnis Sandeep C.
- Sack George H.
- Sacks Frank M.
- Sadoine Margaux L.
- Safaei Soroush
- Saggar Manish
- Saito Yu
- Salama Mohamed F.
- Saleh Sherif
- Sallmon Hannes
- Sampson Christopher
- Santos Manuela
- Saudemont Aurore
- Sava Gianni
- Schmidt Axel
- Schmutz Axel
- Schneeberger Pierre H.H.
- Schrading Simone
- Schramm Alexander
- Schreiber Martin
- Schuele Birgitt
- Schuler Sidney
- Schulte Leon N.
- Schuon Robert A.
- Schurr Roey
- Schwotzer Daniela
- Schymkowitz Joost
- Sczyrba Alexander
- Searles Stephen
- Sebastian Agata
- Seib Kate L.
- Selinski Jennifer
- Seltmann Stefanie
- Senghore Thomas
- Seow Esmond
- Sepanski Robert
- Sergeant Kjell
- Sha Feng
- Shabalin Ivan G.
- Shahid Shaouli
- Shalchyan Vahid
- Shalev Nir
- Shang Jin-Long
- Sharma Neeraj
- Sharma Saurab
- Sheehan Barry
- Shen Jun
- Shi Chunhu
- Shi Han-Ping
- Shimada Tomohiro
- Shin Jeon-Soo
- Shirvalkar Prasad
- Shiryayev Oleg
- Shohayeb Belal
- Shortt Colette
- Siebers Robert
- Sillanp\ue4\ue4 Elina
- Silveyra Patricia
- Singer Josef
- Singh Jugpreet
- Singh Mandeep
- Singh Manisha
- Skinner Debra
- Small Ian
- Smeets Paul A.M.
- Smith Simon S.
- Smith Taylor
- Smout Michael J.
- So Po-Wah
- Soares Ant\uf3nio
- Solano Francisco
- Solomon-Moore Emma
- Sommerlad Andrew
- Sonenshine Daniel E.
- Song Chunjiao
- Song Haijun
- Song Jiangning
- Song Lijuan
- Soraggi Samuele
- Sorzano Carlos O.
- Southall Tony
- Speakman John R.
- Spearman Paul
- Srinivasan Mandyam V.
- Srivastava Kshitij
- Srivastava Rupesh K.
- Stabile Laura P.
- Staege Martin S.
- Stanley Ryan
- Stasiak A.
- Steadman Kathryn J.
- Steckhan Nico
- Stein Nils
- Stella Alessandro
- Stephens Andrew W.
- Stevanovic Dejan
- Stewart Christopher J.
- Stewart Douglas I.
- Stine Keith
- Storlazzi Curt
- Stoynova Nataliya V.
- Strehlow Jan
- Strobl Frederic
- Strzalka Wojciech
- Suarez Oscar M.
- Subhash Santhilal
- Subissi Lorenzo
- Subramaniapillai Mehala
- Sukocheva Olga
- Sultana Taranum
- Sumant Anirudha V.
- Summers Mathew J.
- Sun Gang
- Sun Jim
- Sun Xianbao
- Sundar Raghav
- Supriyanto Irwan
- Surve Chinmay R.
- Suzuki Tomo
- Swali Ritu
- Sydes Matthew
- Syme Caitlin
- Szabo Attila
- Szymanski Wiktor
- Tacon Paul
- Taherzadeh Ghazaleh
- Tahir Nur D.M.
- Tai Chan N.P.
- Takeuchi Hisashi
- Tamaian Radu
- Tan Aik-Choon
- Tan Cher M.
- Tan Ene-Choo
- Tan Kok H.
- Tanadini-Lang S.
- Tanaka Kozo
- Tang Fei
- Tang Haixu
- Tang Jun
- Tang Young
- Tanino Y.
- Tantawy Marwa
- Tao Wanyin
- Targett-Adams Paul
- Tayebi Mourad
- Tayyem Reema
- Tebbe Christoph C.
- Telfer Evelyn E.
- Tellechea Juan I.
- Tempel Wolfram
- Tennakoon Sumudu
- Teodorczyk-Injeyan Julita A.
- Terrier Olivier
- Teseo Serafino
- Testa Jean
- Testoni Ines
- Theron G.
- Thijs Gert
- Thomas Lisa-Marie
- Thorne Sally
- Thrift Amanda G.
- Tian Chang F.
- Tian Yu-Shi
- Tian Zhiqi
- Tiffon Celine
- Tingting Qian
- Tinnefeld Philip
- Tjahjono Daryono H.
- Toelzer Christine
- Tofani Marco
- Tolle Fabrice
- Tomov Nikola
- Tong Xin
- Torga Gonzalo
- Toth Ervin
- Tovar Miguel
- Tr\uf6der Simon E.
- Tran Linh
- Tressoldi Patrizio
- Tripathi Sushil
- Tsapas Apostolos
- Tsirigotis Konstantinos
- Tuladhar Anil M.
- Turak Ayse
- Tuttle Lisa M.
- Tuttle Neil
- Tzotzos George
- Uchendu Florence
- Udo Edet E.
- Uhle Florian
- Ukubuiwe Azubuike C.
- Ung Carolina O.L.
- Utsumi Toshiaki
- Uversky Vladimir N.
- Vaidyanathan Subramanian
- Vaillant Michel
- Valenti Anna
- Valgepea Kaspar
- Valsesia Armand
- van de Mortel Thea
- van den Bos Wouter
- van Dessel Pieter
- van Meerten Tom
- van Nieuwerburgh Filip
- van Raaij Mark J.
- van Ruitenbeek Jan
- Vandenbroucke Roosmarijn E.
- Vanneste Sven
- Vatanparast Hamid
- Vavvas Demetrios G.
- Veiga Feliciano H.
- Vendrell Marc
- Verheijen Geert P.
- Verloh Niklas
- Verlot Pierre
- Vesk Peter A.
- Veys Ralf
- Vickers Paul
- Vickstrom Casey
- Victor Victor M.
- Vidal Arnau
- Villemur Richard
- Villet Martin H.
- Vindin Howard
- Vitriol Veronica
- Viveiros Miguel
- Vohl Marie-Claude
- Voolstra Christian R.
- Vorholt Julia A.
- Voskarides Konstantinos
- Voutchkova Denitza D.
- Vuillemin Anne
- Wakelin Steven
- Waldron Levi
- Walker Mirella
- Walsh Laurence J.
- Wang Amanda Y.
- Wang Fang
- Wang Fuan
- Wang Horng-Dar
- Wang Jinhui
- Wang Jiucun
- Wang Jun
- Wang Qing
- Wang Teng
- Wang Xiaomin
- Wang Yun
- Wang Zhenxing
- Watanabe Yoichi
- Watari Ricky
- Waugh Jason
- Webb S.A.
- Webster Rebecca
- Webster Ruth
- Wei Junnian
- Wei Pan
- Weigert Andreas
- Weinstock Christof
- Welter Danielle
- Wen Jet-Chau
- Werner Gijsbert D.A.
- Werten Sebastiaan
- Westermair Anna L.
- Wham Carol
- White Ethan P.
- Wibowo David
- Widera Darius
- Wiener Jan
- Wilharm Gottfried
- Wilkinson Simon
- Williams Brendan A.
- Williams Richard
- Willmann Raffaella
- Wilson Alex
- Wilson Coralie
- Wingenbach Tanja S.H.
- Winslade Matthew
- Wirth Brunhilde
- Wojan Timothy R.
- Woldesemayat Adugna A.
- Wolff Mathieu
- Wong Alvin
- Wong Bryan M.
- Workman Alan D.
- Wu Dalei
- Wu Tzu-Wei
- Wu Yi-Rui
- Wuerbel Hanno
- Wyart [NO FIRST NAME IN SCOPUS]
- Xavier Rose M.
- Xia Wenfeng
- Xiang Tingxiu
- Xiao Han
- Xiao Shumin
- Xiao Xiangshu
- Xie Li-Xin
- Xiong Peng
- Xu Beisi
- Xu Dong
- Xu Haotian
- Xu J.W.
- Xu Jialin
- Xu Jianping
- Xu Juan
- Xu Jun
- Xu Shicai
- Xu Shilin
- Xu Taosheng
- Xu Ziyue
- Xue Bin
- Xue Yu
- Yadollahpour Ali
- Yalcin Suayib
- Yamato Masayuki
- Yan Hong
- Yang Chongjun
- Yang Dongdong
- Yang En-Cheng
- Yang Hui
- Yang Long
- Yang Mingjun
- Yang Shiqi
- Yang Sunny Y.
- Yang Wei
- Yang Yongliang
- Yankilevich Patricio
- Yao Ruifeng
- Yao Wen
- Yassine Abdul-Amir
- Ye Yuzhen
- Ye Zhi-Qiang
- Yeung Andy W.K.
- Yin Cong-Cong
- Yin Qinan
- Yli-Kauhaluoma Jari
- Yoneyama Hiroshi
- Yoon Jihoon G.
- You Yuyi
- Yousefzadeh Abbas
- Yu Chenglong
- Yu Ying
- Yu Yongbo
- Yuan Christina M.
- Yuan Guo-Cheng
- Yuh Chiou-Hwa
- Zabetakis Ioannis
- Zaccolo Manuela
- Zaitsu Masayoshi
- Zare Asma
- Zaritsky Arno
- Zaucha Jan
- Zeineb Zian
- Zeng Chen
- Zeng Erliang
- Zeng Zhen
- Zevnik Branko
- Zhan Jian
- Zhan Xiao-Yong
- Zhang Chengrong
- Zhang Chi
- Zhang Chongxing
- Zhang Gong
- Zhang Haowen
- Zhang Jilei
- Zhang Junpeng
- Zhang Kai
- Zhang Li
- Zhang Linxing
- Zhang Rongqiang
- Zhang Tongchuan
- Zhang Tuo
- Zhang Wei
- Zhang Weijia
- Zhang Xianglilan
- Zhang Xiaolei
- Zhang Yao
- Zhang Yi
- Zhang Yingkai
- Zhang Yusen
- Zhang Zhe
- Zhang Zhiyong
- Zhang Zhong-Yin
- Zhang Zhongheng
- Zhao Guoyan
- Zhao Haochen
- Zhao Jing
- Zhao Xin
- Zhao Yuan
- Zheng Shan
- Zhou Bailing
- Zhou Jianyu
- Zhou Kai
- Zhou Min
- Zhou Xiaofan
- Zhou Xiaoyan
- Zhou Yaoqi
- Zhu Dongjie
- Zhu Shu
- Zhu Zhenxing
- Ziegler Andreas
- Zinke Katharina
- Zuberbier Torsten
- Zuckerman Hannah
- Publication venue
- Publication date
- 01/01/2019
- Field of study
Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical research.Peer reviewe
Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications
- Author
- Adam Snook
- Adrian J. Hobbs
- Aikaterini I. Argyriou
- Albert Smolenski
- Albert T. Profy
- Alessandro Cataliotti
- Alexander Froese
- Alexander Kollau
- Alexander Kollau
- Alexander Vincent
- Alexandre Dumoulin
- Ali Banijamali
- Alisa Kamynina
- Amie J. Moyes
- Amrita Ahluwalia
- Andrea Gerling
- Andrea Hembre Ulsund
- Andrea Neubauer
- Andreas Friebe
- Andreas Friebe
- Andreas Friebe
- Andreas Friebe
- Andreas Friebe
- Andreas Friebe
- Andreas Friebe
- Andreas Friebe
- Andreas Friebe
- Andreas Güldner
- Andreas Papapetropoulos
- Andrew Tobin
- Andriana Stamopoulou
- Andrzej Weichsel
- Angela McLaughlin
- Angelos Vachaviolos
- Annemarie Aue
- Annemarie Aue
- Annemarie Aue
- Antonius C. F. Gorren
- Arnab Ghosh
- Arno Fritsch
- Astrid Schrammel
- Astrid Schrammel
- Astrid Schrammel
- Astrid Weiss
- Athanassios Giannis
- Atsuko Okamoto
- Attila Oláh
- Axel Gödecke
- B. Selin Kenet
- Balázs Tamás Németh
- Banumathi Sankaran
- Barbara Voussen
- Barbara Voussen
- Barbara Wilhelm
- Bernd J. Pichler
- Bernd Mayer
- Bernd Mayer
- Bernd Mayer
- Bernd Wissinger
- Boris Tchernychev
- Béla Merkely
- Camila B. Almeida
- Carine M. Boustany
- Carla F. F. Penteado
- Catherine Mansfield
- Cheng-Yu Chen
- Chieri Takeuchi
- Choel Kim
- Choel Kim
- Choel Kim
- Choel Kim
- Chris Sarko
- Christian Dees
- Christian Meier
- Christian Schön
- Christine E. Gee
- Christopher Newton-Cheh
- Claire Poulet
- Clara D. Ledsky
- Cor de Wit
- Cor de Witt
- Corina Russwurm
- Cornelia Virus
- Courtney Shea
- Csaba Mátyás
- César Ibarra-Alvarado
- Damian Brockschnieder
- Daniel P. Zimmer
- Daniel Richards
- Daniela Bertinetti
- Dante Merlino
- Darren Casteel
- Darren E. Casteel
- David A. Kass
- David Kilpatrick
- David Langleben
- David Langleben
- Deborah M. Dickey
- Dennis Busse
- Dennis J. Stuehr
- Diane Wong
- Dianna M. Milewicz
- Dieter Groneberg
- Dieter Groneberg
- Dieter Groneberg
- Ditta Zobor
- Dominik M. Fischer
- Donald B. Bloch
- Dong I. Lee
- Dongjian Hu
- Donté A. Stevens
- Doris Koesling
- Doris Koesling
- Doris Koesling
- Doris Koesling
- Doris Koesling
- Dorit Möhrle
- Eberhart Zrenner
- Edward Seto
- Ekkehard Grünig
- Elena Walter
- Elke Butt
- Emmanuel S. Buys
- Emrah Eroglu
- Erik S. Blomain
- Ernst-Martin Füchtbauer
- Eugen Franz
- Eugen Franz
- Evanthia Mergia
- Fabian Schwiering
- Fabian Schwiering
- Fabian Schwiering
- Fabiola Zakia Mónica
- Ferid Murad
- Fernando F. Costa
- Finn Olav Levy
- Finn Olav Levy
- Finn Olav Levy
- Finn Olav Levy
- Flavia Menezes
- Francheska Colon-Gonzalez
- Frank Eitner
- Friederike Cuello
- Friedrich Grimminger
- Friedrich W. Herberg
- Friedrich W. Herberg
- Fritz G. Rathjen
- Fritz G. Rathjen
- Frode Berven
- G-Yoon Jamie Im
- G. Todd Milne
- G. Todd Milne
- G. Todd Milne
- Gaia Calamera
- Gaia Calamera
- Garyfalia Makrynitsa
- Georgios A. Spyroulias
- Gerald Wölkart
- Gerburg K. Schwaerzer
- Gerhard Hannig
- Gilbert W. Kim
- Glenn A. Reinhart
- Gordon L. Warren
- Guang Liu
- Guang Liu
- Guang-Rong Wang
- Gzona Bajraktari
- Gábor Szabó
- Gérald Simonneau
- Hanan Chweih
- Hannes Schmidt
- Hannes Schmidt
- Hans-Ulrich Häring
- Harald H. H. W. Schmidt
- Harald Langer
- Hariharan Subramanian
- Heinz G. Körschen
- Henriette Andresen
- Heribert Schunkert
- Hirofumi Tachibana
- Hiroshi Hosoda
- Hiroshi Hosoda
- Holly Clifford
- Hong Wang
- Hongxing Chen
- Hossein-Ardeschir Ghofrani
- Hu Sheng Qian
- Huaqun Zhang
- Hyazinth Dobrowinski
- Hyun-Soon Geisler
- Ibrahim J. Domian
- Inmaculada Silos-Santiago
- Ioannis I. Alexandropoulos
- Isabelle Lamarre
- Jaime L. Masferrer
- Jaime L. Masferrer
- James C. Campbell
- James E. Sheppeck
- James E. Sheppeck
- James R. Klinger
- James Wakefield
- Jan D. Huizinga
- Jan Giesen
- Jana Wobst
- Jeanette Erdmann
- Jenna Scotcher
- Jennifer E. Van Eyk
- Jenny Tobin
- Jens Schlossmann
- Jeong Joo Kim
- Jeong Joo Kim
- Jeremy R. Egbert
- Jeremy Richman
- Jerid W. Robinson
- Jerid W. Robinson
- Jessica A. Wales
- Jieru E. Lin
- Joerg Reinders
- Johanna Weiss
- Johannes-Peter Stasch
- John T. Fassett
- Jonas Keppler
- Jonathan C. Schisler
- Joon Jung
- Joon Jung
- Jordi Villà-Freixa
- Joseph R. Burgoyne
- Julia Davydova
- Julia Gorelik
- Jun Hino
- Jun Hino
- Jürgen Burhenne
- Ka Bian
- Kanako Takamatsu
- Karl Ulrich Bartz-Schmidt
- Karoline Dröbner
- Katharina Beck
- Katharina Beck
- Katharina Frank
- Katherine Hall
- Kathleen A. Lincoln
- Katja Stehfest
- Katrin Reimann
- Kenji Kangawa
- Kenji Kangawa
- Kenji Kangawa
- Kerstin Jurk
- Kim C. Mansky
- Kim Tang
- Kimberly Long
- Kirk L. Peterson
- Kjestine Schmidt
- Kjestine Schmidt
- Kjetil W. Andressen
- Kjetil Wessel Andressen
- Kjetil Wessel Andressen
- Koichi Miura
- Koichi Miura
- Konstantina Stathopoulou
- Kristen M. Kokkonen
- Kristin Hartmann
- Kálmán Benke
- Lai Wen
- Lai Wen
- Lan Zhao
- Lars I. Leichert
- Laurinda A. Jaffe
- Laurinda A. Jaffe
- Laurinda Jaffe
- Leia C. Shuhaibar
- Lincoln R. Potter
- Lincoln R. Potter
- Lincoln R. Potter
- Linda Breci
- Lise Román Moltzau
- Lise Román Moltzau
- Liying Qin
- Luis Agulló
- Lukas Rüttiger
- M. Wittwer
- Mahmood Alam
- Mai Kadomatsu
- Manuela Harloff
- Manuela Zaccolo
- Manuela Zaccolo
- Mara Goetz
- Marc Humbert
- Marcel A. Krüger
- Marcus Olbrich
- Maria Hernandez-Valladares
- Marianne Bjørnerem
- Marina Bantzi
- Marissa Opelt
- Marissa Opelt
- Marius M. Hoeper
- Marius Ueffing
- Mark Aronovitz
- Mark Currie
- Mark G. Currie
- Mark J. Ranek
- Markus Waldeck-Weiermair
- Markus Wolters
- Markus Wolters
- Markus Wolters
- Marlies Knipper
- Martin Biel
- Martin Deile
- Martin Floor
- Martin Thunemann
- Martin Thunemann
- Masayuki Sasaki
- Mathew M. Mannion
- Mathias Seeliger
- Matthias Broser
- Matthias Karck
- Meinoshin Okumura
- Meinrad Gawaz
- Mi Kyung Chang
- Michael J. Shipston
- Michael Paolillo Hannes Schmidt
- Michael Russwurm
- Michael Russwurm
- Michael Russwurm
- Michael Russwurm
- Michel Négrerie
- Mihály Ruppert
- Mika Takai
- Miki Arai
- Mikiya Miyazato
- Mikiya Miyazato
- Min Zhang
- Monte S. Willis
- Moritz Lehners
- Motofumi Kumazoe
- Motofumi Kumazoe
- Motofumi Kumazoe
- Nadine Mauro
- Nadja I. Bork
- Nancy D. Dalton
- Navin Kapur
- Nazareno Paolocci
- Nicholas Blixt
- Nicola Conran
- Nicole Eichert
- Nicoletta C. Surdo
- Obiajulu Agha
- Oleksandra Prysyazhna
- Oleksandra Prysyazhna
- Oleksandra Prysyazhna
- Olena Rudyk
- Olga N. Petrova
- Oliver Pagel
- on behalf of the Ironwood team
- Ornella Manfra
- Pablo Colorado
- Pamela L. Brito
- Paul A. Corris
- Paul A. Renhowe
- Paul C. Harrison
- Paul S. Frenette
- Pavel I. Nedvetsky
- Pavel Jansa
- Peter Germano
- Peter Hegemann
- Peter P. Rainer
- Peter Ruth
- Peter Sandner
- Peter Sandner
- Peter Wright
- Philip Eaton
- Philip Eaton
- Philip Eaton
- Philip Eaton
- Philipp Henning
- Ping Zhang
- Péter Hegedűs
- Q. Luo
- Ralf Kühn
- Ralph Schermuly
- Raymond L. Benza
- RD-CURE consortium
- Regine Mühlfriedel
- Reiner Frey
- Renate Pilz
- Rene Zahedi
- Renee Sarno
- Renee Sarno
- Reshma S. Baliga
- Richard C. Page
- Richard Karas
- Robert Baumgartner
- Robert Blanton
- Robert Feil
- Robert Feil
- Robert Feil
- Robert Feil
- Robert Feil
- Robert Feil
- Robert Lukowski
- Robert Naeije
- Robert Solinga
- Roger Flores-Costa
- Roland Malli
- Ronald J. Holewinski
- Ryan Fryer
- S. A. Dames
- S. Bruce King
- Sandra Frankenreiter
- Sandy M. Chu
- Sara S. O. Saad
- Sara Vandenwijngaert
- Sarah Helena Nies
- Sarah Jacobson
- Sarah Jacobson
- Saurav Misra
- Scott A. Waldman
- Sean P. Parsons
- Selene J. Sollie
- Sevil Korkmaz-Icöz
- Shatanik Mukherjee
- Shiliang Li
- Shinpei Kawaoka
- Shun Hiroi
- Shunhui Zhuang
- Sian E. Harding
- Silja Meier
- Simone Romoli
- Sivakanan Loganathan
- Sonia Donzelli
- Sophie Schobesberger
- Stavros Topouzis
- Stefan Hell
- Stefan Z. Lutz
- Stefanie Peters
- Steffen Wolter
- Stepan Gambaryan
- Stephan Rosenkranz
- Steven S. Pullen
- Stylianos Michalakis
- Susanne Feil
- Susanne Feil
- Susanne Kohl
- Susanne Krasemann
- Sylvia Nikkho
- Sylvie Bernier
- Sylvie G. Bernier
- Takashi Nojiri
- Takashi Nojiri
- Takashi Nojiri
- Takeshi Tokudome
- Takeshi Tokudome
- Tamás Radovits
- Thomas G. Oertner
- Thorsten Kessler
- Timothy Calamaras
- Tobias Bauch
- Tobias Peters
- Ulrich Walter
- Ulrike Scheib
- Ulrike Zimmermann
- V. Kaila
- Viacheslav O. Nikolaev
- Viacheslav O. Nikolaev
- Viacheslav O. Nikolaev
- Viacheslav O. Nikolaev
- Vikas Kapil
- Vineet Agrawal
- Vu Thao-Vi Dao
- Walter E. Haefeli
- Wendy Baur
- William R. Montfort
- Wilson A. Ferreira
- Wolfgang F. Graier
- Yasutake Tanaka
- Yigao Huang
- Ying-Ju Sung
- Yue Dai
- Yusu Gu
- Yutaka Suzuki
- Zhi Cheng Jing
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2017
- Field of study
This work was supported by a restricted research grant of Bayer AG
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples
- Author
- A Gordon Robertson
- Abdullah Kahraman
- Abel Gonzalez-Perez
- Adam A Margolin
- Adam Abeshouse
- Adam Grundhoff
- Adam J Struck
- Adam J Struck
- Adam J Wright
- Adam Lambert
- Adam P Butler
- Adam P Butler
- Adel El-Naggar
- Adnan M Nagrial
- Adrian Ally
- Adrian Baez-Ortega
- Adrian Thorogood
- Adriana Salcedo
- Adrienne M Flanagan
- Ake Borg
- Akihiro Fujimoto
- Akihiro Suzuki
- Akinyemi I Ojesina
- Alain Viari
- Alan J Robertson
- Alan P Hoyle
- Alan Thompson
- Alasdair Stenhouse
- Alastair M Thompson
- Aldo Scarpa
- Alessandro Pastore
- Alex Buchanan
- Alex Buchanan
- Alexander Claviez
- Alexander J Lazar
- Alexander Martinez-Fundichely
- Alfonso Muñoz
- Alfonso Valencia
- Aliaksei Z Holik
- Alice Meng
- Alicia L Bruzos
- Allison Creason
- Allison P Heath
- Alvin Wei Tian Ng
- Alvis Brazma
- Amaro Taylor-Weiner
- Amber L Johns
- Amie Radenbaugh
- Amit G Deshwar
- Ana Dueso-Barroso
- Ana Mijalkovic Mijalkovic-Lazic
- Ana Milovanovic
- Ana Milovanovic
- Andre Kahles
- Andrea Haake
- Andrea Holbrook
- Andrea L Richardson
- Andrea Mafficini
- Andrea Ruzzenente
- Andreas Behren
- Andreas Rosenwald
- Andreia V Pinho
- Andrew Berchuck
- Andrew D Cherniack
- Andrew J Dunford
- Andrew J Mungall
- Andrew J Spillane
- Andrew Menzies
- Andrew Menzies
- Andrew P Barbour
- Andrew Tutt
- Andrew V Biankin
- Andrey Korshunov
- Andrés Lanzós
- Andy Cafferkey
- Andy G Lynch
- Angela Chou
- Angela N Brooks
- Angela Tam
- Angelica Ochoa
- Angelika N Christ
- Angelo P Dei Tos
- Anieta M Sieuwerts
- Anil K Sood
- Anita Langerød
- Anja Füllgrabe
- Anke K Bergmann
- Ann-Marie Patch
- Anna deFazio
- Anna Ehinger
- Anna Fitzgerald
- Anne Hamilton
- Anne Vincent-Salomon
- Anne Y Warren
- Anne-Lise Børresen-Dale
- Annegien Broeks
- Anthony DiBiase
- Anthony J Gill
- Anthony Ng
- Anthony R Green
- Antonia L Pritchard
- Antonio Pea
- Antonios Koures
- Aparna Prasad
- Apurva M Hegde
- Aquila Fatima
- Arcadi Navarro
- Arie B Brinkman
- Arif O Harmanci
- Arindam Maitra
- Armando Lopez-Guillermo
- Arndt Borkhardt
- Arnoud Boot
- Asger Hobolth
- Ashley Williams
- Ashton A Connor
- Atul J Butte
- Aurélien Chateigner
- Austin J Hepperla
- Axel Aretz
- Aya Sasaki-Oku
- Ayellet V Segre
- B F Francis Ouellette
- Bailey Matthew H
- Barbara Hutter
- Barbara Hutter
- Barbara Kremeyer
- Bartha M Knoppers
- Beifang Niu
- Beifang Niu
- Beifang Niu
- Benedikt Brors
- Benita Kiat Tee Tan
- Benjamin J Raphael
- Benjamin P Berman
- Benjamin Raeder
- Bernardo Rodriguez-Martin
- Bernhard Radlwimmer
- Bernice H Wong
- Beth Karlan
- Bin Tean Teh
- Bin Zhu
- Birgit Burkhardt
- Bishoy M Faltas
- Bodil Bjerkehagen
- Bogdan Czerniak
- Boris Winterhoff
- Borislav C Rusev
- Bradly G Wouters
- Brandi N Davis-Dusenbery
- Brian Craft
- Brian D O'Connor
- Brian Patrick O'Neill
- Brice Aminou
- Calvin Wing Yiu Chan
- Cameron M Soulette
- Carl Herrmann
- Carl Morrison
- Carlo Gambacorti-Passerini
- Carlos Caldas
- Carlos D Bustamante
- Carlos López-Otín
- Carlota Rubio-Perez
- Carmen Gomez
- Carolien H M van Deurzen
- Carolyn M Hutter
- Carolyn M Hutter
- Carrie Cibulskis
- Caterina Vicentini
- Catherine A Shang
- Catherine D Moser
- Catherine J Kennedy
- Catrina C Fronick
- Chad J Creighton
- Chandra Sekhar Pedamallu
- Chang Li
- Charles David Imbusch
- Charles M Perou
- Charles Saller
- Charles Short
- Charlie E Massie
- Chawalit Pairojkul
- Chen Hong
- Chen Ye
- Cheng-Zhong Zhang
- Chin-Lee Wu
- Chip Stewart
- Chip Stewart
- Chip Stewart
- Choon Kiat Ong
- Chris Lawerenz
- Chris Mitchell
- Chris Sander
- Christian von Mering
- Christiane Buchholz
- Christina K Yung
- Christina K Yung
- Christina Yau
- Christine A Iacobuzio-Donahue
- Christine Chomienne
- Christine Desmedt
- Christine P'ng
- Christof von Kalle
- Christoph Borst
- Christoph Plass
- Christopher A Miller
- Christopher Benz
- Christopher J Scarlett
- Christopher J Yoon
- Christopher K Wong
- Christopher M Lalansingh
- Christopher M Lalansingh
- Christopher Ogden
- Christopher S Foster
- Christopher Umbricht
- Christopher W Toon
- Christos Sotiriou
- Cindy Bell
- Cinzia Cantù
- Ciyue Shen
- Claes Wadelius
- Clare Verrill
- Clarissa Gerhauser
- Claudia Calabrese
- Claudio Bassi
- Claudio Luchini
- Claudiu Farcas
- Clemency Jolly
- Colin A Purdie
- Colin A Semple
- Colin C Collins
- Colin S Cooper
- Conrad R Leonard
- Constance H Li
- Corbin D Jones
- Craig Shriver
- Cristina López
- Cyriac Kandoth
- Cyril Fisher
- D Neil Hayes
- Dai-Ying Wu
- Daiming Fan
- Daisuke Komura
- Dale W Garsed
- Daniel A Leongamornlert
- Daniel Baumhoer
- Daniel Hübschmann
- Daniel J Turner
- Daniel J Weisenberger
- Daniel M Berney
- Daniel Rosebrock
- Daniel S Brewer
- Daniela S Gerhard
- Danielle Pasternack
- Darell Bigner
- Dariush Etemadmoghadam
- Darlene Lee
- Darrin F Taylor
- Dave Larson
- David A Wheeler
- David A Wheeler
- David C Wedge
- David Craft
- David D L Bowtell
- David E Neal
- David Haan
- David Haussler
- David Haussler
- David Hedley
- David Huntsman
- David I Heiman
- David J Adams
- David J Van Den Berg
- David K Chang
- David K Miller
- David Khoo
- David Mutch
- David N Louis
- David Nicol
- David Ocana
- David R Jones
- David R Jones
- David Scott
- David T Bowen
- David T W Jones
- David Tamborero
- David Torrents
- David Torrents
- David Townend
- David Vicente
- Davide Antonello
- Declan Cahill
- Denis Larsimont
- Denis Yuen
- Denise Brooks
- Deniz Demircioğlu
- Dennis C Sgroi
- Dennis Karsch
- Dennis T Maglinte
- Dennis Wigle
- Derek W Wright
- Dianne E Chadwick
- Dido Lenze
- Dieter Kube
- Dieter Weichenhan
- Dilip D Giri
- Dimitri Livitz
- Dimitri Livitz
- Dimple Chakravarty
- Ding
- Dirk Schadendorf
- Dmitry A Gordenin
- Dominik Glodzik
- Don Chalmers
- Dong Guanlan
- Dongbing Liu
- Donghoon Lee
- Donghui Tan
- Donna M Muzny
- Dorthe Grabau
- Douglas A Levine
- Douglas F Easton
- Douglas Voet
- Duncan Beardsmore
- Dursi Lewis Jonathan
- Edward W Rowe
- Eigo Shimizu
- Ekta Khurana
- Elaine R Mardis
- Electron Kebebew
- Elena Piñeiro-Yáñez
- Elena Provenzano
- Elias Campo
- Elisabet Barrera
- Elisabetta Sereni
- Elizabeth A Musgrove
- Elizabeth L Appelbaum
- Elizabeth L Christie
- Elli Papaemmanuil
- Ellrott Kyle
- Emilie Lalonde
- Eoghan Harrington
- Eric Chuah
- Eric Green
- Eric Lander
- Eric Minwei Liu
- Eric Z Ma
- Eric Z Ma
- Erik Garrison
- Erik Larsson
- Erik Mayer
- Erik N Bergstrom
- Erin Curley
- Ermin Hodzic
- Erwin G Van Meir
- Esa Pitkänen
- Esther Rheinbay
- Esther Rheinbay
- Eun Pyo Hong
- Eunjung Alice Lee
- Eva G Alvarez
- Eva Hellstrom-Lindberg
- Ewan Birney
- F Germán Rodríguez-González
- Fabien C Lamaze
- Fabien Calvo
- Fabio C P Navarro
- Faiyaz Notta
- Fan Yang
- Fan Zhang
- Faraz Hach
- Faraz Hach
- Faridah Mbabaali
- Fatima Al-Shahrour
- Federico Abascal
- Fei-Fei Liu
- Felicity Newell
- Fenglin Liu
- Fernanda Amary
- Ferran Muiños
- Florian Markowetz
- Fouad Yousif
- Francesc Muyas
- Francesco Favero
- Francisco M De La Vega
- Francisco Sanchez-Vega
- Fraser R Duthie
- Fred Sweep
- Freddie C Hamdy
- Fruzsina Molnár-Gábor
- Fumie Hosoda
- G Petur Nielsen
- G Steven Bova
- Gad Getz
- Gad Getz
- Gad Getz
- Gaetan MacGrogan
- Gaetano Finocchiaro
- Gary D Bader
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- Nikita Desai
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- Stuart R Jefferys
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- Subhajit Sengupta
- Sue Merson
- Suet-Feung Chin
- Sultan T Al-Sedairy
- Sung-Min Ahn
- Sung-Soo Yoon
- Sunghoon Cho
- Sunil R Lakhani
- Suresh Ramalingam
- Susan Bullman
- Susanna L Cooke
- Sushant Kumar
- Sushant Kumar
- Suyash S Shringarpure
- Syed Haider
- Sylvia Asa
- Søren Brunak
- Takafumi N Yamaguchi
- Takafumi N Yamaguchi
- Takanori Hasegawa
- Takashi Yugawa
- Takashi Yugawa
- Takuji Okusaka
- Tal Shmaya
- Tannistha Nandi
- Taobo Hu
- Taobo Hu
- Tapio Visakorpi
- Tara J Skelly
- Tari A King
- Tatsuhiko Tsunoda
- Tatsuhiro Shibata
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- Tetsuo Ushiku
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- Timothy J Underwood
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- Tirso Pons
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- Tobias Rausch
- Todd A Johnson
- Todd D Pihl
- Tom Bodenheimer
- Tom Mikkelsen
- Tom Roques
- Tomas J Tanskanen
- Tomas Marques-Bonet
- Tomoko Urushidate
- Torill Sauer
- Toru Nakamura
- Treasa A McPherson
- Troy Shelton
- Tsun-Po Yang
- Ultan McDermott
- Umadevi Veluvolu
- Umut H Toprak
- Valerie Jakrot
- Varsha Tembe
- Vasilisa A Rudneva
- Venkata D Yellapantula
- Venkata D Yellapantula
- Vera B Kaiser
- Veronica Y Sabelnykova
- Victor Reuter
- Vikram Deshpande
- Viktoriya Korchina
- Ville Mustonen
- Vinayak Bhandari
- Vincent Ferretti
- Vincent Huang
- Vincent Huang
- Vincent J Gnanapragasam
- Vincent Khoo
- Vincenzo Corbo
- Vishal S Chandan
- Volker Hovestadt
- W Kimryn Rathmell
- W M Linehan
- Walker Hale
- Wan Choi
- Wanding Zhou
- Wang Liang-Bo
- Weerasinghe Amila
- Wei Jiao
- Wendl Michael C
- Wenyi Wang
- Wenyi Wang
- Wenyi Wang
- Wheeler David A
- William B Isaacs
- William C Faquin
- William Friedman
- William Howat
- William U Meyerson
- Willie Yu
- Winghing Wong
- Wojciech Bazant
- Wolfgang Huber
- Wolfram Klapper
- Xavier Estivill
- Xavier Pivot
- Xiao Xiao
- Xiaobo Li
- Xiaoping Su
- Xiaotong Li
- Xiaotong Yao
- Xing Hua
- Xingmin Liu
- Xinyue Li
- Xiuqing Zhang
- Xiuqing Zheng
- Xose S Puente
- Xuan Le
- Xuanping Zhang
- Xuemei Luo
- Xueqing Zou
- Yan Shi
- Yan Zhang
- Yang Wu
- Yang Yang
- Yann Joly
- Yanxun Xu
- Yao He
- Yasin Senbabaoglu
- Yassen Assenov
- Yasser Riazalhosseini
- Yasuhito Arai
- Yasushi Rino
- Yasushi Totoki
- Yeng Ang
- Yi Huang
- Yi Huang
- Yifei Men
- Yiling Lu
- Yilong Li
- Yingyan Yu
- Yiwen Chen
- Yogesh Kumar
- Yogesh Kumar
- Yoke-Eng Chiew
- Yong Hou
- Yong Zhou
- Yong-Jie Lu
- Yongzhan Nie
- Yosef E Maruvka
- Yosef E Maruvka
- Yoshiiku Kawakami
- Young Seok Ju
- Youngchoon Woo
- Youngil Koh
- Youngwook Kim
- Youyong Lu
- Yu Fan
- Yu Fan
- Yu Fan
- Yu-Jia Shiah
- Yuan Ji
- Yuan Yuan
- Yuichi Shiraishi
- Yulia Newton
- Yulia Rubanova
- Yumeng Wang
- Yupeng Cun
- Yussanne Ma
- Zachary Heins
- Zechen Chong
- Zechen Chong
- Zemin Zhang
- Zhaohong Chen
- Zhenggang Wu
- Zhenggang Wu
- Zhining Wang
- Zhongming Zhao
- Ziao Lin
- Zsofia Kote-Jarai
- Ólafur Andri Stefánsson
- Øystein Garred
- Publication venue
- Nature Communications
- Publication date
- 01/01/2020
- Field of study
Funder: NCI U24CA211006Abstract: The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome sequencing (WES) and whole genome sequencing (WGS), respectively. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2,658 cancers across 38 tumour types, we compare WES and WGS side-by-side from 746 TCGA samples, finding that ~80% of mutations overlap in covered exonic regions. We estimate that low variant allele fraction (VAF < 15%) and clonal heterogeneity contribute up to 68% of private WGS mutations and 71% of private WES mutations. We observe that ~30% of private WGS mutations trace to mutations identified by a single variant caller in WES consensus efforts. WGS captures both ~50% more variation in exonic regions and un-observed mutations in loci with variable GC-content. Together, our analysis highlights technological divergences between two reproducible somatic variant detection efforts
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- Author
- Aaltonen Lauri A.
- Abascal Federico
- Abeshouse Adam
- Aburatani Hiroyuki
- Adams David J.
- Agrawal Nishant
- Ahn Keun Soo
- Ahn Sung-Min
- Aikata Hiroshi
- Akbani Rehan
- Akdemir Kadir C.
- Al-Ahmadie Hikmat
- Al-Sedairy Sultan T.
- Al-Shahrour Fatima
- Alawi Malik
- Albert Monique
- Aldape Kenneth
- Alexandrov Ludmil B.
- Ally Adrian
- Alsop Kathryn
- Alvarez Eva G.
- Amary Fernanda
- Amin Samirkumar B.
- Aminou Brice
- Ammerpohl Ole
- Anderson Matthew J.
- Ang Yeng
- Antonello Davide
- Anur Pavana
- Aparicio Samuel
- Appelbaum Elizabeth L.
- Arai Yasuhito
- Aretz Axel
- Arihiro Koji
- Ariizumi Shun-ichi
- Armenia Joshua
- Arnau Gisela Mir
- Arnould Laurent
- Asa Sylvia
- Assenov Yassen
- Atwal Gurnit
- Aukema Sietse
- Auman J. Todd
- Aure Miriam R.
- Awadalla Philip
- Aymerich Marta
- Bader Gary D.
- Baez-Ortega Adrian
- Bailey Matthew H.
- Bailey Peter J.
- Balasundaram Miruna
- Balu Saianand
- Bandopadhayay Pratiti
- Banks Rosamonde E.
- Barbi Stefano
- Barbour Andrew P.
- Barenboim Jonathan
- Barnholtz-Sloan Jill
- Barr Hugh
- Barrera Elisabet
- Bartlett John
- Bartolome Javier
- Bassi Claudio
- Bathe Oliver F.
- Baumhoer Daniel
- Bavi Prashant
- Baylin Stephen B.
- Bazant Wojciech
- Beardsmore Duncan
- Beck Timothy A.
- Behjati Sam
- Behren Andreas
- Bell Cindy
- Beltran Sergi
- Benz Christopher
- Berchuck Andrew
- Bergmann Anke K.
- Bergstrom Erik N.
- Berman Benjamin P.
- Berney Daniel M.
- Bernhart Stephan H.
- Beroukhim Rameen
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- Bertl Johanna
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- Bhandari Vinayak
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- Bieg Matthias
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- Vincent-Salomon Anne
- Visakorpi Tapio
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- von Kalle Christof
- von Mering Christian
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- Waddell Nicola
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- Wadi Lina
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- Wintersinger Jeffrey A.
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- Wong Tina
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- Wright Adam J.
- Wright Derek W.
- Wright Mark H.
- Wu Chin-Lee
- Wu Dai-Ying
- Wu Guanming
- Wu Jianmin
- Wu Kui
- Wu Yang
- Wu Zhenggang
- Xi Liu
- Xia Tian
- Xiang Qian
- Xiao Xiao
- Xing Rui
- Xiong Heng
- Xu Qinying
- Xu Yanxun
- Xue Hong
- Yachida Shinichi
- Yakneen Sergei
- Yamaguchi Rui
- Yamaguchi Takafumi N.
- Yamamoto Masakazu
- Yamamoto Shogo
- Yamaue Hiroki
- Yang Fan
- Yang Huanming
- Yang Jean Y.
- Yang Liming
- Yang Lixing
- Yang Shanlin
- Yang Tsun-Po
- Yang Yang
- Yao Xiaotong
- Yaspo Marie-Laure
- Yates Lucy
- Yau Christina
- Ye Chen
- Ye Kai
- Yellapantula Venkata D.
- Yoon Christopher J.
- Yoon Sung-Soo
- Yousif Fouad
- Yu Jun
- Yu Kaixian
- Yu Willie
- Yu Yingyan
- Yuan Ke
- Yuan Yuan
- Yuen Denis
- Yugawa Takashi
- Yung Christina K.
- Zaikova Olga
- Zamora Jorge
- Zapatka Marc
- Zenklusen Jean C.
- Zenz Thorsten
- Zeps Nikolajs
- Zhang Cheng-Zhong
- Zhang Fan
- Zhang Hailei
- Zhang Hongwei
- Zhang Hongxin
- Zhang Jiashan
- Zhang Jing
- Zhang Junjun
- Zhang Xiuqing
- Zhang Xuanping
- Zhang Yan
- Zhang Zemin
- Zhao Zhongming
- Zheng Liangtao
- Zheng Xiuqing
- Zhou Wanding
- Zhou Yong
- Zhu Bin
- Zhu Hongtu
- Zhu Jingchun
- Zhu Shida
- Zou Lihua
- Zou Xueqing
- Publication venue
- Nature Communications
- Publication date
- 28/08/2020
- Field of study
Funder: Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada (NSERC Canadian Network for Research and Innovation in Machining Technology); doi: https://doi.org/10.13039/501100002790Funder: Genome Canada (Génome Canada); doi: https://doi.org/10.13039/100008762Funder: Canada Foundation for Innovation (Fondation canadienne pour l'innovation); doi: https://doi.org/10.13039/501100000196Funder: Terry Fox Research Institute (Institut de Recherche Terry Fox); doi: https://doi.org/10.13039/501100004376Abstract: Sex differences have been observed in multiple facets of cancer epidemiology, treatment and biology, and in most cancers outside the sex organs. Efforts to link these clinical differences to specific molecular features have focused on somatic mutations within the coding regions of the genome. Here we report a pan-cancer analysis of sex differences in whole genomes of 1983 tumours of 28 subtypes as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium. We both confirm the results of exome studies, and also uncover previously undescribed sex differences. These include sex-biases in coding and non-coding cancer drivers, mutation prevalence and strikingly, in mutational signatures related to underlying mutational processes. These results underline the pervasiveness of molecular sex differences and strengthen the call for increased consideration of sex in molecular cancer research
Sex differences in oncogenic mutational processes
- Author
- A Gordon Robertson
- Abdullah Kahraman
- Abel Gonzalez-Perez
- Adam A Margolin
- Adam Abeshouse
- Adam Grundhoff
- Adam J Struck
- Adam J Wright
- Adam Lambert
- Adam Margolin
- Adam P Butler
- Adel El-Naggar
- Adnan M Nagrial
- Adrian Ally
- Adrian Baez-Ortega
- Adrian Thorogood
- Adriana Salcedo
- Adrienne M Flanagan
- Ake Borg
- Akihiro Fujimoto
- Akihiro Suzuki
- Akinyemi I Ojesina
- Alain Viari
- Alan J Robertson
- Alan P Hoyle
- Alan Thompson
- Alasdair Stenhouse
- Alastair M Thompson
- Aldo Scarpa
- Alessandro Pastore
- Alex Buchanan
- Alexander Claviez
- Alexander J Lazar
- Alexander J Lazar
- Alexander Martinez-Fundichely
- Alfonso Muñoz
- Alfonso Valencia
- Aliaksei Z Holik
- Alice Meng
- Alicia L Bruzos
- Allison P Heath
- Alvin Wei Tian Ng
- Alvis Brazma
- Amaro Taylor-Weiner
- Amber L Johns
- Amit G Deshwar
- Ana Dueso-Barroso
- Ana Mijalkovic Mijalkovic-Lazic
- Ana Milovanovic
- Andre Kahles
- Andrea Haake
- Andrea Holbrook
- Andrea L Richardson
- Andrea Mafficini
- Andrea Ruzzenente
- Andreas Behren
- Andreas Rosenwald
- Andreia V Pinho
- Andrew Berchuck
- Andrew D Cherniack
- Andrew J Dunford
- Andrew J Mungall
- Andrew J Spillane
- Andrew Menzies
- Andrew P Barbour
- Andrew Tutt
- Andrew V Biankin
- Andrew V Biankin
- Andrey Korshunov
- Andrés Lanzós
- Andy Cafferkey
- Andy G Lynch
- Angela Chou
- Angela N Brooks
- Angela Tam
- Angelica Ochoa
- Angelika N Christ
- Angelo P Dei Tos
- Anieta M Sieuwerts
- Anil K Sood
- Anita Langerød
- Anja Füllgrabe
- Anke K Bergmann
- Ann-Marie Patch
- Anna deFazio
- Anna Ehinger
- Anna Fitzgerald
- Anne Hamilton
- Anne Vincent-Salomon
- Anne Y Warren
- Anne-Lise Børresen-Dale
- Annegien Broeks
- Anthony DiBiase
- Anthony J Gill
- Anthony Ng
- Anthony R Green
- Antonia L Pritchard
- Antonio Pea
- Antonios Koures
- Aparna Prasad
- Apurva M Hegde
- Aquila Fatima
- Arcadi Navarro
- Arie B Brinkman
- Arif O Harmanci
- Arindam Maitra
- Armando Lopez-Guillermo
- Arndt Borkhardt
- Arnoud Boot
- Asger Hobolth
- Ashley Williams
- Ashton A Connor
- Atul J Butte
- Aurélien Chateigner
- Austin J Hepperla
- Axel Aretz
- Aya Sasaki-Oku
- Ayellet V Segre
- B F Francis Ouellette
- Barbara Hutter
- Barbara Kremeyer
- Bartha M Knoppers
- Beifang Niu
- Benedikt Brors
- Benita Kiat Tee Tan
- Benjamin J Raphael
- Benjamin P Berman
- Benjamin Raeder
- Bernardo Rodriguez-Martin
- Bernhard Radlwimmer
- Bernice H Wong
- Beth Karlan
- Bin Tean Teh
- Bin Zhu
- Birgit Burkhardt
- Bishoy M Faltas
- Bishoy M Faltas
- Bodil Bjerkehagen
- Bogdan Czerniak
- Boris Winterhoff
- Borislav C Rusev
- Boutros
- Bradly G Wouters
- Brandi N Davis-Dusenbery
- Brian Craft
- Brian D O'Connor
- Brian Patrick O'Neill
- Brice Aminou
- Calvin Wing Yiu Chan
- Cameron M Soulette
- Carl Herrmann
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- Carlo Gambacorti-Passerini
- Carlos Caldas
- Carlos D Bustamante
- Carlos López-Otín
- Carlota Rubio-Perez
- Carmen Gomez
- Carolien H M van Deurzen
- Carolyn M Hutter
- Carrie Cibulskis
- Caterina Vicentini
- Catherine A Shang
- Catherine D Moser
- Catherine J Kennedy
- Catrina C Fronick
- Chad J Creighton
- Chandra Sekhar Pedamallu
- Chang Li
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- Charles Saller
- Charles Short
- Charlie E Massie
- Chawalit Pairojkul
- Chen Hong
- Chen Ye
- Cheng-Zhong Zhang
- Chin-Lee Wu
- Chin-Lee Wu
- Chip Stewart
- Chovon Kiat Ong
- Chris Lawerenz
- Chris Mitchell
- Chris Sander
- Christian von Mering
- Christiane Buchholz
- Christina K Yung
- Christina Yau
- Christine A Iacobuzio-Donahue
- Christine Chomienne
- Christine Desmedt
- Christine P'ng
- Christine P'ng
- Christof von Kalle
- Christoph Borst
- Christoph Plass
- Christopher A Miller
- Christopher Benz
- Christopher J Scarlett
- Christopher J Yoon
- Christopher M Lalansingh
- Christopher Ogden
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- Cindy Bell
- Cinzia Cantù
- Ciyue Shen
- Claes Wadelius
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- Claudia Calabrese
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- Clemency Jolly
- Colin A Purdie
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- Cyril Fisher
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- Daiming Fan
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- Dale W Garsed
- Daniel A Leongamornlert
- Daniel Baumhoer
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- Daniel S Brewer
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- Danielle Pasternack
- Darell Bigner
- Dariush Etemadmoghadam
- Darlene Lee
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- David A Wheeler
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- Dennis Wigle
- Derek W Wright
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- Dianne E Chadwick
- Dido Lenze
- Dieter Kube
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- Dilip D Giri
- Dimitri Livitz
- Dimple Chakravarty
- Dirk Schadendorf
- Dmitry A Gordenin
- Dominik Glodzik
- Don Chalmers
- Dongbing Liu
- Donghoon Lee
- Donghui Tan
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- Dorthe Grabau
- Douglas A Levine
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- Electron Kebebew
- Elena Piñeiro-Yáñez
- Elena Provenzano
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- Elisabet Barrera
- Elisabetta Sereni
- Elizabeth A Musgrove
- Elizabeth L Appelbaum
- Elizabeth L Christie
- Elli Papaemmanuil
- Emilie Lalonde
- Eoghan Harrington
- Eric Chuah
- Eric Green
- Eric Lander
- Eric Minwei Liu
- Eric Z Ma
- Erik Garrison
- Erik Larsson
- Erik Mayer
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- Erin Curley
- Ermin Hodzic
- Erwin G Van Meir
- Esa Pitkänen
- Esther Rheinbay
- Esther Rheinbay
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- Eunjung Alice Lee
- Eva G Alvarez
- Eva Hellstrom-Lindberg
- Ewan Birney
- F Germán Rodríguez-González
- Fabien C Lamaze
- Fabien Calvo
- Fabio C P Navarro
- Faiyaz Notta
- Fan Yang
- Fan Zhang
- Faraz Hach
- Faridah Mbabaali
- Fatima Al-Shahrour
- Federico Abascal
- Fei-Fei Liu
- Felicity Newell
- Fenglin Liu
- Fernanda Amary
- Ferran Muiños
- Florian Markowetz
- Francesc Muyas
- Francesco Favero
- Francisco M De La Vega
- Francisco Sanchez-Vega
- Fraser R Duthie
- Fred Sweep
- Freddie C Hamdy
- Fruzsina Molnár-Gábor
- Fumie Hosoda
- G Petur Nielsen
- G Petur Nielsen
- G Steven Bova
- Gad Getz
- Gad Getz
- Gaetan MacGrogan
- Gaetano Finocchiaro
- Gary D Bader
- Gavin Ha
- Gavin W Wilson
- Genta Nagae
- Geoff Macintyre
- George B Hanna
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- Georgia Escaramis
- Georgina V Long
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- German M Demidov
- German Ott
- Gerrit K Hooijer
- Gert G Van den Eynden
- Ghislaine Scelo
- Giada Bonizzato
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- Gilles Romieu
- Gilles Thomas
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- Giuseppe Malleo
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- Gordon Saksena
- Grace Tiao
- Graham J Mann
- Grant Sanders
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- Guido Reifenberger
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- Haiyan Irene Li
- Han Liang
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- Hidewaki Nakagawa
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- Hirofumi Rokutan
- Hirokazu Taniguchi
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- Hong Xue
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- Hongwei Zhang
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- Hugh Barr
- Hui Shen
- Husen M Umer
- Huy Q Dinh
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- Hyung-Yong Kim
- Hyunghwan Kim
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- Ian Welch
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- Ignaty Leshchiner
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- Javier Bartolome
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- Sun Ren X
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- Sunghoon Cho
- Sunil R Lakhani
- Suresh Ramalingam
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- Susanna L Cooke
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- Tatsuhiro Shibata
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- Thomas J Matthew
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- Timothy J Underwood
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- Tirso Pons
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- Tobias Rausch
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- Venkata D Yellapantula
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- Vera B Kaiser
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- Victor Reuter
- Vikram Deshpande
- Vikram Deshpande
- Viktoriya Korchina
- Ville Mustonen
- Vinayak Bhandari
- Vincent Ferretti
- Vincent Huang
- Vincent J Gnanapragasam
- Vincent Khoo
- Vincenzo Corbo
- Vishal S Chandan
- Volker Hovestadt
- W Kimryn Rathmell
- W M Linehan
- Wan Choi
- Wanding Zhou
- Wei Jiao
- Wei Jiao
- Wenyi Wang
- William B Isaacs
- William C Faquin
- William C Faquin
- William Friedman
- William Howat
- William Meyerson
- Willie Yu
- Winghing Wong
- Wojciech Bazant
- Wolfgang Huber
- Wolfram Klapper
- Xavier Estivill
- Xavier Pivot
- Xiao Xiao
- Xiaobo Li
- Xiaoping Su
- Xiaotong Li
- Xiaotong Yao
- Xing Hua
- Xingmin Liu
- Xinyue Li
- Xiuqing Zhang
- Xiuqing Zheng
- Xose S Puente
- Xuan Le
- Xuanping Zhang
- Xuemei Luo
- Xueqing Zou
- Yan Shi
- Yan Zhang
- Yang Wu
- Yang Yang
- Yann Joly
- Yanxun Xu
- Yao He
- Yasin Senbabaoglu
- Yassen Assenov
- Yasser Riazalhosseini
- Yasuhito Arai
- Yasushi Rino
- Yasushi Totoki
- Yeng Ang
- Yi Huang
- Yiling Lu
- Yilong Li
- Yingyan Yu
- Yiwen Chen
- Yogesh Kumar
- Yoke-Eng Chiew
- Yong Hou
- Yong Zhou
- Yong-Jie Lu
- Yongzhan Nie
- Yosef E Maruvka
- Yoshiiku Kawakami
- Young Seok Ju
- Youngchoon Woo
- Youngil Koh
- Youngwook Kim
- Yousif Fouad
- Youyong Lu
- Yu Fan
- Yu-Jia Shiah
- Yuan Ji
- Yuan Yuan
- Yuichi Shiraishi
- Yulia Newton
- Yulia Rubanova
- Yumeng Wang
- Yupeng Cun
- Yussanne Ma
- Zachary Heins
- Zechen Chong
- Zemin Zhang
- Zhaohong Chen
- Zhenggang Wu
- Zhining Wang
- Zhongming Zhao
- Ziao Lin
- Zsofia Kote-Jarai
- Ólafur Andri Stefánsson
- Øystein Garred
- Publication venue
- Publication date
- 01/01/2020
- Field of study
Sex differences have been observed in multiple facets of cancer epidemiology, treatment and biology, and in most cancers outside the sex organs. Efforts to link these clinical differences to specific molecular features have focused on somatic mutations within the coding regions of the genome. Here we report a pan-cancer analysis of sex differences in whole genomes of 1983 tumours of 28 subtypes as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium. We both confirm the results of exome studies, and also uncover previously undescribed sex differences. These include sex-biases in coding and non-coding cancer drivers, mutation prevalence and strikingly, in mutational signatures related to underlying mutational processes. These results underline the pervasiveness of molecular sex differences and strengthen the call for increased consideration of sex in molecular cancer research.Sex differences have been observed in multiple facets of cancer epidemiology, treatment and biology, and in most cancers outside the sex organs. Efforts to link these clinical differences to specific molecular features have focused on somatic mutations within the coding regions of the genome. Here we report a pan-cancer analysis of sex differences in whole genomes of 1983 tumours of 28 subtypes as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium. We both confirm the results of exome studies, and also uncover previously undescribed sex differences. These include sex-biases in coding and non-coding cancer drivers, mutation prevalence and strikingly, in mutational signatures related to underlying mutational processes. These results underline the pervasiveness of molecular sex differences and strengthen the call for increased consideration of sex in molecular cancer research.Peer reviewe
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Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples
- Author
- Aaltonen Lauri A.
- Abascal Federico
- Abeshouse Adam
- Aburatani Hiroyuki
- Adams David J.
- Agrawal Nishant
- Ahn Keun Soo
- Ahn Sung-Min
- Aikata Hiroshi
- Akbani Rehan
- Akdemir Kadir C.
- Al-Ahmadie Hikmat
- Al-Sedairy Sultan T.
- Al-Shahrour Fatima
- Alawi Malik
- Albert Monique
- Aldape Kenneth
- Alexandrov Ludmil B.
- Ally Adrian
- Alsop Kathryn
- Alvarez Eva G.
- Amary Fernanda
- Amin Samirkumar B.
- Aminou Brice
- Ammerpohl Ole
- Anderson Matthew J.
- Ang Yeng
- Antonello Davide
- Anur Pavana
- Aparicio Samuel
- Appelbaum Elizabeth L.
- Arai Yasuhito
- Aretz Axel
- Arihiro Koji
- Ariizumi Shun-ichi
- Armenia Joshua
- Arnau Gisela Mir
- Arnould Laurent
- Asa Sylvia
- Assenov Yassen
- Atwal Gurnit
- Aukema Sietse
- Auman J. Todd
- Aure Miriam R.
- Awadalla Philip
- Aymerich Marta
- Bader Gary D.
- Baez-Ortega Adrian
- Bailey Matthew H.
- Bailey Peter J.
- Balasundaram Miruna
- Balu Saianand
- Bandopadhayay Pratiti
- Banks Rosamonde E.
- Barbi Stefano
- Barbour Andrew P.
- Barenboim Jonathan
- Barnholtz-Sloan Jill
- Barr Hugh
- Barrera Elisabet
- Bartlett John
- Bartolome Javier
- Bassi Claudio
- Bathe Oliver F.
- Baumhoer Daniel
- Bavi Prashant
- Baylin Stephen B.
- Bazant Wojciech
- Beardsmore Duncan
- Beck Timothy A.
- Behjati Sam
- Behren Andreas
- Bell Cindy
- Beltran Sergi
- Benz Christopher
- Berchuck Andrew
- Bergmann Anke K.
- Bergstrom Erik N.
- Berman Benjamin P.
- Berney Daniel M.
- Bernhart Stephan H.
- Beroukhim Rameen
- Berrios Mario
- Bersani Samantha
- Bertl Johanna
- Betancourt Miguel
- Bhandari Vinayak
- Bhosle Shriram G.
- Biankin Andrew V.
- Bieg Matthias
- Bigner Darell
- Bin Zhu
- Binder Hans
- Birney Ewan
- Birrer Michael
- Biswas Nidhan K.
- Bjerkehagen Bodil
- Bodenheimer Tom
- Boice Lori
- Bonizzato Giada
- Boot Arnoud
- Bootwalla Moiz S.
- Borg Ake
- Borkhardt Arndt
- Boroevich Keith A.
- Borozan Ivan
- Borst Christoph
- Bosenberg Marcus
- Bosio Mattia
- Boultwood Jacqueline
- Bourque Guillaume
- Boutros Paul C.
- Bova G. Steven
- Bowen David T.
- Bowlby Reanne
- Bowtell David D. L.
- Boyault Sandrine
- Boyce Rich
- Boyd Jeffrey
- Brazma Alvis
- Brennan Paul
- Brewer Daniel S.
- Brinkman Arie B.
- Bristow Robert G.
- Broaddus Russell R.
- Brock Jane E.
- Brock Malcolm
- Broeks Annegien
- Brooks Angela N.
- Brooks Denise
- Brors Benedikt
- Brunak Søren
- Bruxner Timothy J. C.
- Bruzos Alicia L.
- Buchanan Alex
- Buchhalter Ivo
- Buchholz Christiane
- Bullman Susan
- Burke Hazel
- Burkhardt Birgit
- Burns Kathleen H.
- Busanovich John
- Bustamante Carlos D.
- Butler Adam P.
- Butte Atul J.
- Byrne Niall J.
- Børresen-Dale Anne-Lise
- Caesar-Johnson Samantha J.
- Cafferkey Andy
- Cahill Declan
- Calabrese Claudia
- Caldas Carlos
- Calvo Fabien
- Camacho Niedzica
- Campbell Peter J.
- Campo Elias
- Cantù Cinzia
- Cao Shaolong
- Carey Thomas E.
- Carlevaro-Fita Joana
- Carlsen Rebecca
- Cataldo Ivana
- Cazzola Mario
- Cebon Jonathan
- Cerfolio Robert
- Chadwick Dianne E.
- Chakravarty Dimple
- Chalmers Don
- Chan Calvin Wing Yiu
- Chan Kin
- Chan-Seng-Yue Michelle
- Chandan Vishal S.
- Chang David K.
- Chanock Stephen J.
- Chantrill Lorraine A.
- Chateigner Aurélien
- Chatterjee Nilanjan
- Chayama Kazuaki
- Chen Hsiao-Wei
- Chen Jieming
- Chen Ken
- Chen Yiwen
- Chen Zhaohong
- Cherniack Andrew D.
- Chien Jeremy
- Chiew Yoke-Eng
- Chin Suet-Feung
- Chiotti Kami
- Cho Juok
- Cho Sunghoon
- Choi Jung Kyoon
- Choi Wan
- Chomienne Christine
- Chong Zechen
- Choo Su Pin
- Chou Angela
- Christ Angelika N.
- Christie Elizabeth L.
- Chuah Eric
- Cibulskis Carrie
- Cibulskis Kristian
- Cingarlini Sara
- Clapham Peter
- Claviez Alexander
- Cleary Sean
- Cloonan Nicole
- Cmero Marek
- Collins Colin C.
- Connor Ashton A.
- Cooke Susanna L.
- Cooper Colin S.
- Cope Leslie
- Corbo Vincenzo
- Cordes Matthew G.
- Cordner Stephen M.
- Cortés-Ciriano Isidro
- Covington Kyle
- Cowin Prue A.
- Craft Brian
- Craft David
- Creason Allison
- Creighton Chad J.
- Cun Yupeng
- Curley Erin
- Cutcutache Ioana
- Czajka Karolina
- Czerniak Bogdan
- Dagg Rebecca A.
- Danilova Ludmila
- Davi Maria Vittoria
- Davidson Natalie R.
- Davies Helen
- Davis Ian J.
- Davis-Dusenbery Brandi N.
- Dawson Kevin J.
- De Bono Johann S.
- De La Vega Francisco M.
- De Paoli-Iseppi Ricardo
- deFazio Anna
- Defreitas Timothy
- Dei Tos Angelo P.
- Delaneau Olivier
- Demchok John A.
- Demeulemeester Jonas
- Demidov German M.
- Demircioğlu Deniz
- Dennis Nening M.
- Denroche Robert E.
- Dentro Stefan C.
- Desai Nikita
- Deshpande Vikram
- Deshwar Amit G.
- Desmedt Christine
- Deu-Pons Jordi
- Dhalla Noreen
- Dhani Neesha C.
- Dhingra Priyanka
- Dhir Rajiv
- Diamanti Klev
- DiBiase Anthony
- Ding Li
- Ding Shuai
- Dinh Huy Q.
- Dirix Luc
- Doddapaneni HarshaVardhan
- Dong Guanlan
- Donmez Nilgun
- Dow Michelle T.
- Drapkin Ronny
- Drechsel Oliver
- Drews Ruben M.
- Dudderidge Tim
- Dueso-Barroso Ana
- Dunford Andrew J.
- Dunn Michael
- Dursi Lewis Jonathan
- Duthie Fraser R.
- Dutton-Regester Ken
- Eagles Jenna
- Easton Douglas F.
- Edmonds Stuart
- Edwards Paul A.
- Edwards Sandra E.
- Eeles Rosalind A.
- Ehinger Anna
- Eils Juergen
- Eils Roland
- El-Naggar Adel
- Eldridge Matthew
- Ellrott Kyle
- Erkek Serap
- Escaramis Georgia
- Espiritu Shadrielle M. G.
- Estivill Xavier
- Etemadmoghadam Dariush
- Eyfjord Jorunn E.
- Faltas Bishoy M.
- Fan Daiming
- Fan Yu
- Faquin William C.
- Farcas Claudiu
- Fassan Matteo
- Fatima Aquila
- Favero Francesco
- Fayzullaev Nodirjon
- Felau Ina
- Fereday Sian
- Ferguson Martin L.
- Ferretti Vincent
- Feuerbach Lars
- Field Matthew A.
- Fink J. Lynn
- Finocchiaro Gaetano
- Fisher Cyril
- Fittall Matthew W.
- Fitzgerald Anna
- Fitzgerald Rebecca C.
- Flanagan Adrienne M.
- Fleshner Neil E.
- Flicek Paul
- Foekens John A.
- Foltz Steven
- Fong Kwun M.
- Fonseca Nuno A.
- Foster Christopher S.
- Fox Natalie S.
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- Niu Beifang
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- Ohi Kazuhiro
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- Ojima Hidenori
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- Omberg Larsson
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- Ott German
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- O’Donnell Peter
- O’Donovan Maria
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- O’Neill J. Robert
- Paczkowska Marta
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- Pairojkul Chawalit
- Pajic Marina
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- Potapova Olga
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- Prinz Manuel
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- Rabionet Raquel
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- Radovic Petar
- Raeder Benjamin
- Raghavan K. Vijay
- Raine Keiran M.
- Ramakrishna Manasa
- Ramakrishnan Kamna
- Ramalingam Suresh
- Raphael Benjamin J.
- Rathmell W. Kimryn
- Rausch Tobias
- Reifenberger Guido
- Reimand Jüri
- Reis-Filho Jorge
- Reuter Victor
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- Rheinbay Esther
- Riazalhosseini Yasser
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- Ringel Matthew
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- Rippe Karsten
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- Rodriguez Javier Bartolomé
- Rodriguez-Martin Bernardo
- Rodríguez-González F. Germán
- Roehrl Michael H. A.
- Rohde Marius
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- Romieu Gilles
- Rooman Ilse
- Roques Tom
- Rosebrock Daniel
- Rosenberg Mara
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- Rosenwald Andreas
- Rowe Edward W.
- Royo Romina
- Rozen Steven G.
- Rubanova Yulia
- Rubin Mark A.
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- Rudneva Vasilisa A.
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- Sadeghi Sara
- Sahinalp S. Cenk
- Saini Natalie
- Saito-Adachi Mihoko
- Saksena Gordon
- Salcedo Adriana
- Salgado Roberto
- Salichos Leonidas
- Sallari Richard
- Saller Charles
- Salvia Roberto
- Sam Michelle
- Samra Jaswinder S.
- Sanchez-Vega Francisco
- Sander Chris
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- Sarrafi Iman
- Sasaki-Oku Aya
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- Scarlett Christopher J.
- Scarpa Aldo
- Scelo Ghislaine
- Schadendorf Dirk
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- Schlesner Matthias
- Schlomm Thorsten
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- Schreiber Stefan
- Schultz Nikolaus
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- Schwarz Roland F.
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- Scully Ralph
- Seethala Raja
- Segre Ayellet V.
- Selander Iris
- Semple Colin A.
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- Serra Stefano
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- Shah Nimish C.
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- Shimizu Eigo
- Shimizu Kiyo
- Shin Seung Jun
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- Shmulevich Ilya
- Shorser Solomon I.
- Short Charles
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- Shuai Shimin
- Sidiropoulos Nikos
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- Signoretti Sabina
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- Simbolo Michele
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- Sinnott-Armstrong Nasa
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- Sothi Sharmila
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- Soulette Cameron M.
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- Spillane Andrew J.
- Spiro Oliver
- Spring Jonathan
- Staaf Johan
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- Stefánsson Ólafur Andri
- Stegle Oliver
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- Stenhouse Alasdair
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- Su Hong
- Su Xiaoping
- Sun Ren X.
- Sungalee Stephanie
- Susak Hana
- Suzuki Akihiro
- Sweep Fred
- Szczepanowski Monika
- Sültmann Holger
- Tam Angela
- Tamborero David
- Tan Benita Kiat Tee
- Tan Donghui
- Tan Patrick
- Tanaka Hiroko
- Taniguchi Hirokazu
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- Tarabichi Maxime
- Tarnuzzer Roy
- Tarpey Patrick
- Taschuk Morgan L.
- Tatsuno Kenji
- Tavaré Simon
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- Taylor-Weiner Amaro
- Teague Jon W.
- Teh Bin Tean
- Tembe Varsha
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- Thai Kevin
- Thayer Sarah P.
- Thiessen Nina
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- Thompson Alastair M.
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- Thorne Heather
- Thorne Leigh B.
- Thorogood Adrian
- Tiao Grace
- Tijanic Nebojsa
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- Tirabosco Roberto
- Tojo Marta
- Tommasi Stefania
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- Torrents David
- Tortora Giampaolo
- Tost Jörg
- Totoki Yasushi
- Townend David
- Traficante Nadia
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- Tsunoda Tatsuhiko
- Tubio Jose M. C.
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- Ushiku Tetsuo
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- van Deurzen Carolien H. M.
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- Vincent-Salomon Anne
- Visakorpi Tapio
- Voet Douglas
- von Kalle Christof
- von Mering Christian
- Vyas Paresh
- Vázquez-García Ignacio
- Waddell Nick M.
- Waddell Nicola
- Wadelius Claes
- Wadi Lina
- Wagener Rabea
- Wala Jeremiah A.
- Wang Jian
- Wang Jiayin
- Wang Liang-Bo
- Wang Linghua
- Wang Qi
- Wang Wenyi
- Wang Yumeng
- Wang Zhining
- Waring Paul M.
- Warnatz Hans-Jörg
- Warrell Jonathan
- Warren Anne Y.
- Waszak Sebastian M.
- Wedge David C.
- Weerasinghe Amila
- Weichenhan Dieter
- Weinberger Paul
- Weinstein John N.
- Weischenfeldt Joachim
- Weisenberger Daniel J.
- Welch Ian
- Wendl Michael C.
- Werner Johannes
- Whalley Justin P.
- Wheeler David A.
- Whitaker Hayley C.
- Wigle Dennis
- Wilkerson Matthew D.
- Williams Ashley
- Wilmott James S.
- Wilson Gavin W.
- Wilson Julie M.
- Wilson Richard K.
- Winterhoff Boris
- Wintersinger Jeffrey A.
- Wiznerowicz Maciej
- Wolf Stephan
- Wong Bernice H.
- Wong Christopher K.
- Wong Tina
- Wong Winghing
- Woo Youngchoon
- Wood Scott
- Wouters Bradly G.
- Wright Adam J.
- Wright Derek W.
- Wright Mark H.
- Wu Chin-Lee
- Wu Dai-Ying
- Wu Guanming
- Wu Jianmin
- Wu Kui
- Wu Yang
- Wu Zhenggang
- Xi Liu
- Xia Tian
- Xiang Qian
- Xiao Xiao
- Xing Rui
- Xiong Heng
- Xu Qinying
- Xu Yanxun
- Xue Hong
- Yachida Shinichi
- Yakneen Sergei
- Yamaguchi Rui
- Yamaguchi Takafumi N.
- Yamamoto Masakazu
- Yamamoto Shogo
- Yamaue Hiroki
- Yang Fan
- Yang Huanming
- Yang Jean Y.
- Yang Liming
- Yang Lixing
- Yang Shanlin
- Yang Tsun-Po
- Yang Yang
- Yao Xiaotong
- Yaspo Marie-Laure
- Yates Lucy
- Yau Christina
- Ye Chen
- Ye Kai
- Yellapantula Venkata D.
- Yoon Christopher J.
- Yoon Sung-Soo
- Yousif Fouad
- Yu Jun
- Yu Kaixian
- Yu Willie
- Yu Yingyan
- Yuan Ke
- Yuan Yuan
- Yuen Denis
- Yugawa Takashi
- Yung Christina K.
- Zaikova Olga
- Zamora Jorge
- Zapatka Marc
- Zenklusen Jean C.
- Zenz Thorsten
- Zeps Nikolajs
- Zhang Cheng-Zhong
- Zhang Fan
- Zhang Hailei
- Zhang Hongwei
- Zhang Hongxin
- Zhang Jiashan
- Zhang Jing
- Zhang Junjun
- Zhang Xiuqing
- Zhang Xuanping
- Zhang Yan
- Zhang Zemin
- Zhao Zhongming
- Zheng Liangtao
- Zheng Xiuqing
- Zhou Wanding
- Zhou Yong
- Zhu Hongtu
- Zhu Jingchun
- Zhu Shida
- Zou Lihua
- Zou Xueqing
- Publication venue
- Nature Communications
- Publication date
- 21/09/2020
- Field of study
Funder: NCI U24CA211006Abstract: The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome sequencing (WES) and whole genome sequencing (WGS), respectively. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2,658 cancers across 38 tumour types, we compare WES and WGS side-by-side from 746 TCGA samples, finding that ~80% of mutations overlap in covered exonic regions. We estimate that low variant allele fraction (VAF < 15%) and clonal heterogeneity contribute up to 68% of private WGS mutations and 71% of private WES mutations. We observe that ~30% of private WGS mutations trace to mutations identified by a single variant caller in WES consensus efforts. WGS captures both ~50% more variation in exonic regions and un-observed mutations in loci with variable GC-content. Together, our analysis highlights technological divergences between two reproducible somatic variant detection efforts
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples
- Author
- A Gordon Robertson
- Abdullah Kahraman
- Abel Gonzalez-Perez
- Adam A Margolin
- Adam Abeshouse
- Adam Grundhoff
- Adam J Struck
- Adam J Struck
- Adam J Wright
- Adam Lambert
- Adam P Butler
- Adam P Butler
- Adel El-Naggar
- Adnan M Nagrial
- Adrian Ally
- Adrian Baez-Ortega
- Adrian Thorogood
- Adriana Salcedo
- Adrienne M Flanagan
- Ake Borg
- Akihiro Fujimoto
- Akihiro Suzuki
- Akinyemi I Ojesina
- Alain Viari
- Alan J Robertson
- Alan P Hoyle
- Alan Thompson
- Alasdair Stenhouse
- Alastair M Thompson
- Aldo Scarpa
- Alessandro Pastore
- Alex Buchanan
- Alex Buchanan
- Alexander Claviez
- Alexander J Lazar
- Alexander Martinez-Fundichely
- Alfonso Muñoz
- Alfonso Valencia
- Aliaksei Z Holik
- Alice Meng
- Alicia L Bruzos
- Allison Creason
- Allison P Heath
- Alvin Wei Tian Ng
- Alvis Brazma
- Amaro Taylor-Weiner
- Amber L Johns
- Amie Radenbaugh
- Amit G Deshwar
- Ana Dueso-Barroso
- Ana Mijalkovic Mijalkovic-Lazic
- Ana Milovanovic
- Ana Milovanovic
- Andre Kahles
- Andrea Haake
- Andrea Holbrook
- Andrea L Richardson
- Andrea Mafficini
- Andrea Ruzzenente
- Andreas Behren
- Andreas Rosenwald
- Andreia V Pinho
- Andrew Berchuck
- Andrew D Cherniack
- Andrew J Dunford
- Andrew J Mungall
- Andrew J Spillane
- Andrew Menzies
- Andrew Menzies
- Andrew P Barbour
- Andrew Tutt
- Andrew V Biankin
- Andrey Korshunov
- Andrés Lanzós
- Andy Cafferkey
- Andy G Lynch
- Angela Chou
- Angela N Brooks
- Angela Tam
- Angelica Ochoa
- Angelika N Christ
- Angelo P Dei Tos
- Anieta M Sieuwerts
- Anil K Sood
- Anita Langerød
- Anja Füllgrabe
- Anke K Bergmann
- Ann-Marie Patch
- Anna deFazio
- Anna Ehinger
- Anna Fitzgerald
- Anne Hamilton
- Anne Vincent-Salomon
- Anne Y Warren
- Anne-Lise Børresen-Dale
- Annegien Broeks
- Anthony DiBiase
- Anthony J Gill
- Anthony Ng
- Anthony R Green
- Antonia L Pritchard
- Antonio Pea
- Antonios Koures
- Aparna Prasad
- Apurva M Hegde
- Aquila Fatima
- Arcadi Navarro
- Arie B Brinkman
- Arif O Harmanci
- Arindam Maitra
- Armando Lopez-Guillermo
- Arndt Borkhardt
- Arnoud Boot
- Asger Hobolth
- Ashley Williams
- Ashton A Connor
- Atul J Butte
- Aurélien Chateigner
- Austin J Hepperla
- Axel Aretz
- Aya Sasaki-Oku
- Ayellet V Segre
- B F Francis Ouellette
- Bailey Matthew H
- Barbara Hutter
- Barbara Hutter
- Barbara Kremeyer
- Bartha M Knoppers
- Beifang Niu
- Beifang Niu
- Beifang Niu
- Benedikt Brors
- Benita Kiat Tee Tan
- Benjamin J Raphael
- Benjamin P Berman
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- Bernardo Rodriguez-Martin
- Bernhard Radlwimmer
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- Xueqing Zou
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- Yeng Ang
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- Yi Huang
- Yifei Men
- Yiling Lu
- Yilong Li
- Yingyan Yu
- Yiwen Chen
- Yogesh Kumar
- Yogesh Kumar
- Yoke-Eng Chiew
- Yong Hou
- Yong Zhou
- Yong-Jie Lu
- Yongzhan Nie
- Yosef E Maruvka
- Yosef E Maruvka
- Yoshiiku Kawakami
- Young Seok Ju
- Youngchoon Woo
- Youngil Koh
- Youngwook Kim
- Youyong Lu
- Yu Fan
- Yu Fan
- Yu Fan
- Yu-Jia Shiah
- Yuan Ji
- Yuan Yuan
- Yuichi Shiraishi
- Yulia Newton
- Yulia Rubanova
- Yumeng Wang
- Yupeng Cun
- Yussanne Ma
- Zachary Heins
- Zechen Chong
- Zechen Chong
- Zemin Zhang
- Zhaohong Chen
- Zhenggang Wu
- Zhenggang Wu
- Zhining Wang
- Zhongming Zhao
- Ziao Lin
- Zsofia Kote-Jarai
- Ólafur Andri Stefánsson
- Øystein Garred
- Publication venue
- Publication date
- 01/01/2020
- Field of study
The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome sequencing (WES) and whole genome sequencing (WGS), respectively. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2,658 cancers across 38 tumour types, we compare WES and WGS side-by-side from 746 TCGA samples, finding that ~80% of mutations overlap in covered exonic regions. We estimate that low variant allele fraction (VAF < 15%) and clonal heterogeneity contribute up to 68% of private WGS mutations and 71% of private WES mutations. We observe that ~30% of private WGS mutations trace to mutations identified by a single variant caller in WES consensus efforts. WGS captures both ~50% more variation in exonic regions and un-observed mutations in loci with variable GC-content. Together, our analysis highlights technological divergences between two reproducible somatic variant detection efforts.The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome sequencing (WES) and whole genome sequencing (WGS), respectively. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2,658 cancers across 38 tumour types, we compare WES and WGS side-by-side from 746 TCGA samples, finding that -80% of mutations overlap in covered exonic regions. We estimate that low variant allele fraction (VAFPeer reviewe