796 research outputs found

    One-dimensional Analysis of Impulse Turbine with Self-pitch-controlled Guide Vanes for Wave Power Conversion

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    A classical one-dimensional analysis in turbomachinery was presented to estimate aerodynamic characteristics of an impulse turbine with self-pitch-controlled guide vanes which is proposed by the authors for ocean wave power conversion. With some simplified assumptions, the efficiency vs/flow-rate coefficient curves were calculated and compared with the experimental results both in a unidirectional steady flow condition and a sinusoidally oscillating flow condition. The estimated results reveal a behavior of the actual characteristics curve of the turbine. Possibility of further improvement in efficiency was discussed from a viewpoint of specific speed and specific diameter

    Experimental Research on Performances of Air Turbines for a Fixed Oscillating Water Column-Type Wave Energy Converter

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    A fixed oscillating water column (OWC)-type wave energy converter is composed of an air chamber for primary conversion and an air turbine for secondary conversion. In the optimal design method of a fixed OWC-type wave energy converter, it is necessary to develop a design method which can consider the characteristics of incident wave motion, the motion of the internal free surface affected in the structure such as a partly submerged wall, the fluctuation of air pressure in an air chamber, the rotation of the air turbine. In this paper, the 2-dimensional wave tank tests in regular waves for the performance evaluation of the air turbines in a fixed OWC-type wave energy converter were conducted to obtain the data needed to make this design method. As the results, the effects of the impulse turbine specification such as the rotor inlet/outlet angle, the guide vane's number and the vane's setting angle on the primary and secondary conversion efficiencies are clarified experimentally. Furthermore, the performances of the Wells turbines with different number of blade are presented for comparison of the operating condition

    Effect of Homogeneous Condensation on the Interaction of Supersonic Moist Air Jets with Resonance Tube

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    The Hartmann tube, can use for flow-control, is a device which generates high intensity sound through the shock wave oscillations, are created by the interaction of the supersonic jet. In this study, two-phase flow simulations are carried out to characterize the effect of non-equilibrium condensation on the unsteady flowfield of the Hartmann resonance tube. This present numerical work provides a new insight on the flow dynamics and acoustics of the resonance tube – including the shock nature, the tube gas heating, and the effect of non-equilibrium condensation on the flow structure. A TVD numerical method is applied to the Reynolds and Favre-averaged Navier-Stokes equations, and droplet growth equation of liquid phase production. The simulations are performed over a range of nozzle pressure ratios. The numerically simulated flow structure of under-expanded supersonic jets is compared with experimental data. Moreover, the predicted frequency of end wall pressure fluctuations is compared with the experimental results

    A Small Molecule Inhibitor of Redox-Regulated Protein Translocation into Mitochondria

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    SummaryThe mitochondrial disulfide relay system of Mia40 and Erv1/ALR facilitates import of the small translocase of the inner membrane (Tim) proteins and cysteine-rich proteins. A chemical screen identified small molecules that inhibit Erv1 oxidase activity, thereby facilitating dissection of the disulfide relay system in yeast and vertebrate mitochondria. One molecule, mitochondrial protein import blockers from the Carla Koehler laboratory (MitoBloCK-6), attenuated the import of Erv1 substrates into yeast mitochondria and inhibited oxidation of Tim13 and Cmc1 in in vitro reconstitution assays. In addition, MitoBloCK-6 revealed an unexpected role for Erv1 in the carrier import pathway, namely transferring substrates from the translocase of the outer membrane complex onto the small Tim complexes. Cardiac development was impaired in MitoBloCK-6-exposed zebrafish embryos. Finally, MitoBloCK-6 induced apoptosis via cytochrome c release in human embryonic stem cells (hESCs) but not in differentiated cells, suggesting an important role for ALR in hESC homeostasis

    Incidence, prevalence and prescription patterns of antipsychotic medications use in Asia and US: A cross-nation comparison with common data model

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    The use of antipsychotic medications (APMs) could be different among countries due to availability, approved indications, characteristics and clinical practice. However, there is limited literature providing comparisons of APMs use among countries. To examine trends in antipsychotic prescribing in Taiwan, Hong Kong, Japan, and the United States, we conducted a cross-national study from 2002 to 2014 by using the distributed network approach with common data model. We included all patients who had at least a record of antipsychotic prescription in this study, and defined patients without previous exposure of antipsychotics for 6 months before the index date as new users for incidence estimation. We calculated the incidence, prevalence, and prescription rate of each medication by calendar year. Among older patients, sulpiride was the most incident [incidence rate (IR) 11.0-23.3) and prevalent [prevalence rate (PR) 11.9-14.3) APM in Taiwan, and most prevalent (PR 2.5-3.9) in Japan. Quetiapine and haloperidol were most common in the United States (IR 8.1-9.5; PR 18.0-18.4) and Hong Kong (PR 8.8-13.7; PR 10.6-12.7), respectively. The trend of quetiapine use was increasing in Taiwan, Hong Kong and the United States. As compared to older patients, the younger patients had more propensity to be prescribed second-generation APM for treatment in four countries. Trends in antipsychotic prescribing varied among countries. Quetiapine use was most prevalent in the United States and increasing in Taiwan and Hong Kong. The increasing use of quetiapine in the elderly patients might be due to its safety profile compared to other APMs

    Fast ignitor research at the Institute of Laser Engineering, Osaka University

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    Copyright 2001 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. The following article appeared in Physics of Plasmas, 8(5), 2268-2274, 2001 and may be found at http://dx.doi.org/10.1063/1.135259

    Studies of ultra-intense laser plasma interactions for fast ignition

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    Copyright 2000 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. The following article appeared in Physics of Plasmas, 7(5), 2014-2022, 2000 and may be found at http://dx.doi.org/10.1063/1.87402

    Measurement of the Bottom-Strange Meson Mixing Phase in the Full CDF Data Set

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    We report a measurement of the bottom-strange meson mixing phase \beta_s using the time evolution of B0_s -> J/\psi (->\mu+\mu-) \phi (-> K+ K-) decays in which the quark-flavor content of the bottom-strange meson is identified at production. This measurement uses the full data set of proton-antiproton collisions at sqrt(s)= 1.96 TeV collected by the Collider Detector experiment at the Fermilab Tevatron, corresponding to 9.6 fb-1 of integrated luminosity. We report confidence regions in the two-dimensional space of \beta_s and the B0_s decay-width difference \Delta\Gamma_s, and measure \beta_s in [-\pi/2, -1.51] U [-0.06, 0.30] U [1.26, \pi/2] at the 68% confidence level, in agreement with the standard model expectation. Assuming the standard model value of \beta_s, we also determine \Delta\Gamma_s = 0.068 +- 0.026 (stat) +- 0.009 (syst) ps-1 and the mean B0_s lifetime, \tau_s = 1.528 +- 0.019 (stat) +- 0.009 (syst) ps, which are consistent and competitive with determinations by other experiments.Comment: 8 pages, 2 figures, Phys. Rev. Lett 109, 171802 (2012
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