46 research outputs found
Effect of High vs Low Doses of Chloroquine Diphosphate as Adjunctive Therapy for Patients Hospitalized With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection: A Randomized Clinical Trial.
- Author
- Albuquerque Bernardino C.
- Almeida Araújo Alexandre Marcia
- Bassat Orellana Quique
- Baía-da-Silva Djane
- Brito Marcelo
- Brito-Sousa José Diego
- Cardoso de Melo Gisely
- CloroCovid-19 Team
- Costa Pinto Rosemary
- Croda Júlio
- Daniel-Ribeiro Claudio-Tadeu
- Farias Guerra Marcus Vinitius
- Fonseca Almeida Val Fernando
- Fonseca Pacheco Antonio G.
- Fontes Cor Jesus
- Gomes Mourão Maria Paula
- Gomes Naveca Felipe
- Guimaraes Lacerda Marcus V.
- Hajjar Ludhmila A.
- Lacerda Nogueira Mauricio
- Machado Siqueira André
- Monteiro Wuelton Marcelo
- Oliveira Santos James Dean
- Schwarzbold Alexandre
- Sierra Romero Gustavo A.
- Silva Balieiro Antonio A.
- Silva Borba Mayla Gabriela
- Simao Xavier Mariana
- Souza Sampaio Vanderson de
- Publication venue
- 'American Medical Association (AMA)'
- Publication date
- 22/05/2020
- Field of study
There is no specific antiviral therapy recommended for coronavirus disease 2019 (COVID-19). In vitro studies indicate that the antiviral effect of chloroquine diphosphate (CQ) requires a high concentration of the drug.To evaluate the safety and efficacy of 2 CQ dosages in patients with severe COVID-19. This parallel, double-masked, randomized, phase IIb clinical trial with 81 adult patients who were hospitalized with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was conducted from March 23 to April 5, 2020, at a tertiary care facility in Manaus, Brazilian Amazon. - Patients were allocated to receive high-dosage CQ (ie, 600 mg CQ twice daily for 10 days) or low-dosage CQ (ie, 450 mg twice daily on day 1 and once daily for 4 days). - Label: Main Outcomes and Measures
Primary outcome was reduction in lethality by at least 50% in the high-dosage group compared with the low-dosage group. Data presented here refer primarily to safety and lethality outcomes during treatment on day 13. Secondary end
points included participant clinical status, laboratory examinations, and electrocardiogram results. Outcomes will be presented to day 28. Viral respiratory secretion RNA detection was performed on days 0 and 4. Out of a predefined sample size of 440 patients, 81 were enrolled (41 [50.6%] to high-dosage group and 40 [49.4%] to low-dosage group). Enrolled patients had a mean (SD) age of 51.1 (13.9) years, and most (60 [75.3%]) were men.
Older age (mean [SD] age, 54.7 [13.7] years vs 47.4 [13.3] years) and more heart disease (5 of 28 [17.9%] vs 0) were seen in the high-dose group. Viral RNA was detected in 31 of 40 (77.5%) and 31 of 41 (75.6%) patients in the low-dosage and high-dosage groups, respectively. Lethality until day 13 was 39.0% in the high-dosage group (16 of 41) and 15.0% in the low-dosage group (6 of 40). The high-dosage group presented more instance of QTc interval greater than 500 milliseconds (7 of 37 [18.9%]) compared with the low-dosage group (4 of 36 [11.1%]).
Respiratory secretion at day 4 was negative in only 6 of 27 patients (22.2%). - Label: Conclusions and Relevance
The preliminary findings of this study suggest that the higher CQ dosage should not be recommended for critically ill patients with COVID-19 because of its potential safety hazards, especially when taken concurrently with azithromycin and oseltamivir. These findings cannot be extrapolated to patients with nonsevere COVID-19
Influência de safras agrícolas e tratamentos fungicidas no café cereja descascado e bóia
- Author
- Adriano Andrade Abrahão
- CARVALHO V.D. de
- CARVALHO V.L.
- CHAVES G.M.
- CUNHA R.L.
- FERNANDES S.M.
- Flávio Meira Borém
- FREITAS J.L.P.
- José Carlos Barbosa
- Juliana Costa de Rezende
- LOPES L.M.V.
- MATIELLO J.B.
- MEIRELES A.M.A.
- PIMENTA C.J.
- PIMENTA C.J.
- PIMENTA C.J.
- PINTO N.A.V.D.
- PRETE C.E.C.
- PRETE C.E.C.
- RIBEIRO D.M.
- Rosemary Gualberto Fonseca Alvarenga Pereira
- SILVA R.F.
- SILVA R.F. da
- SOUZA S.C. de
- TEIXEIRA A.A.
- VILELA E.R.
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- 01/01/2009
- Field of study
Rising rural body-mass index is the main driver of the global obesity epidemic in adults
- Author
- Abarca-Gomez Leandra
- Abdeen Ziad A.
- Abdrakhmanova Shynar
- Abu-Rmeileh Niveen M.
- Acosta-Cazares Benjamin
- Adams Robert J.
- Aekplakorn Wichai
- Afsana Kaosar
- Agdeppa Imelda A.
- Aguilar-Salinas Carlos A.
- Agyemang Charles
- Ahmad Mohamad Hasnan
- Ahmad Noor Ani
- Ahmadi Naser
- Ahmadvand Alireza
- Ahrens Wolfgang
- Ajlouni Kamel
- Al Nsour Mohannad
- Al-Hazzaa Hazzaa M.
- Al-Othman Amani Rashed
- Al-Raddadi Rajaa
- AlBuhairan Fadia
- AlDhukair Shahla
- Ali Mohamed M.
- Ali Osman
- Alkerwi Ala'a
- Alvarez-Pedrerol Mar
- Aly Eman
- Amarapurkar Deepak N.
- Amouyel Philippe
- Amuzu Antoinette
- Anderssen Sigmund A.
- Angquist Lars H.
- Anjana Ranjit Mohan
- Ansari-Moghaddam Alireza
- Anselmo Olinto Maria Teresa
- Aounallah-Skhiri Hajer
- Araujo Joana
- Ariansen Inger
- Aris Tahir
- Arku Raphael E.
- Arlappa Nimmathota
- Aryal Krishna K.
- Aspelund Thor
- Assah Felix K.
- Assuncao Maria Cecilia F.
- Aung May Soe
- Auvinen Juha
- Avdicova Maria
- Azevedo Ana
- Azizi Fereidoun
- Azmin Mehrdad
- Babu Bontha V.
- Baharudin Azli
- Bahijri Suhad
- Baker Jennifer L.
- Balakrishna Nagalla
- Bamoshmoosh Mohamed
- Banach Maciej
- Bandosz Piotr
- Banegas Jose R.
- Barbagallo Carlo M.
- Barcelo Alberto
- Barkat Amina
- Barros Aluisio J. D.
- Barros Mauro V. G.
- Bata Iqbal
- Batieha Anwar M.
- Batista Rosangela L.
- Battakova Zhamilya
- Batyrbek Assembekov
- Baur Louise A.
- Beaglehole Robert
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- Ben Romdhane Habiba
- Benedics Judith
- Benet Mikhail
- Bennett James E.
- Bentham James
- Berkinbayev Salim
- Bernabe-Ortiz Antonio
- Bernotiene Gailute
- Bettiol Heloisa
- Bhagyalaxmi Aroor
- Bharadwaj Sumit
- Bhargava Santosh K.
- Bhutta Zulfiqar A.
- Bi Hongsheng
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- Biehl Anna
- Bikbov Mukharram
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- Breda Joao
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- Brinduse Lacramioara
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- Bueno-de-Mesquita H. Bas
- Bugge Anna
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- Burazeri Genc
- Burns Con
- Cabrera de Leon Antonio
- Cacciottolo Joseph
- Cai Hui
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- Caserta Carmelo A.
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- Cesar Juraci A.
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- Chan Angelique W.
- Chan Queenie
- Chaturvedi Himanshu K.
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- Chen Chien-Jen
- Chen Fangfang
- Chen Huashuai
- Chen Shuohua
- Chen Zhengming
- Cheng Ching-Yu
- Cheng Yiling J.
- Chetrit Angela
- Chikova-Iscener Ekaterina
- Chinh Nguyen Huu Chinh Nguyen Huu
- Chiolero Arnaud
- Chiou Shu-Ti
- Chirita-Emandi Adela
- Chirlaque Maria-Dolores
- Cho Belong
- Cho Yumi
- Christensen Kaare
- Christofaro Diego G.
- Chudek Jerzy
- Cifkova Renata
- Cilia Michelle
- Cinteza Eliza
- Claessens Frank
- Clarke Janine
- Clays Els
- Concin Hans
- Confortin Susana C.
- Cooper Cyrus
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- Costanzo Simona
- Cottel Dominique
- Cowan Melanie J.
- Cowell Chris
- Craig Cora L.
- Crampin Amelia C.
- Crujeiras Ana B.
- Cruz Juan J.
- Cucu Alexandra
- Cui Liufu
- D'Arrigo Graziella
- d'Orsi Eleonora
- Dallongeville Jean
- Damasceno Albertino
- Damsgaard Camilla T.
- Danaei Goodarz
- Dankner Rachel
- Dantoft Thomas M.
- Dasgupta Parasmani
- Dastgiri Saeed
- Dauchet Luc
- Davletov Kairat
- De Backer Guy
- De Bacquer Dirk
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- De Ridder Karin
- de Rooij Susanne R.
- De Smedt Delphine
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- Deepa Mohan
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- Delisle Helene
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- El Ati Jalila
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- Engle-Stone Reina
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- Fischer Krista
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- Furusawa Takuro
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- Gates Louise
- Gazzinelli Andrea
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- Gironella Glen
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- Ning Guang
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- Perez Cynthia M.
- Perez-Farinos Napoleon
- Peters Annette
- Petersmann Astrid
- Petkeviciene Janina
- Petrauskiene Ausra
- Petrescu Constanta Huidumac
- Peykari Niloofar
- Pierannunzio Daniela
- Pigeot Iris
- Pikhart Hynek
- Pilav Aida
- Pilotto Lorenza
- Pistelli Francesco
- Pitakaka Freda
- Piwonska Aleksandra
- Plans-Rubio Pedro
- Poh Bee Koon
- Pohlabeln Hermann
- Pop Raluca M.
- Popovic Stevo R.
- Porta Miquel
- Portegies Marileen L. P.
- Posch Georg
- Poulimeneas Dimitrios
- Pouraram Hamed
- Pourshams Akram
- Poustchi Hossein
- Pradeepa Rajendra
- Price Alison J.
- Price Jacqueline F.
- Puder Jardena J.
- Pudule Iveta
- Puhakka Soile E.
- Puiu Maria
- Punab Margus
- Qasrawi Radwan F.
- Qorbani Mostafa
- Quang Ngoc La Quang Ngoc La
- Quang Ngoc Nguyen Quang Ngoc Nguyen
- Radhika Madhari S.
- Radic Ivana
- Radisauskas Ricardas
- Rahim Norsyamlina Che Abdul
- Rahman Mahfuzar
- Rahman Mahmudur
- Raitakari Olli
- Raj Manu
- Rajkumar Hemalatha
- Rakhmatulloev Sherali
- Ramachandran Ambady
- Ramke Jacqueline
- Ramos Elisabete
- Ramos Rafel
- Rampal Lekhraj
- Rampal Sanjay
- Rao Kodavanti Mallikharjuna
- Rao Sudha Ramachandra
- Rascon-Pacheco Ramon A.
- Rasmussen Mette
- Redon Josep
- Reganit Paul Ferdinand M.
- Regecova Valeria
- Revilla Luis
- Ribas-Barba Lourdes
- Ribeiro Robespierre
- Riboli Elio
- Rigo Fernando
- Riley Leanne M.
- Rinaldo Natascia
- Rito Ana
- Ritti-Dias Raphael M.
- Rivera Juan A.
- Robitaille Cynthia
- Rodrigues Daniela
- Rodriguez-Artalejo Fernando
- Rodriguez-Martinez Andrea
- Rodriguez-Villamizar Laura A.
- Rojas-Martinez Rosalba
- Rojroongwasinkul Nipa
- Romaguera Dora
- Rosario Angelika Schaffrath
- Rosengren Annika
- Rouse Ian
- Roy Joel G. R.
- Rubinstein Adolfo
- Ruhli Frank J.
- Ruidavets Jean-Bernard
- Ruiz Moreno Emma
- Russo Paola
- Rust Petra
- Rutkowski Marcin
- Sabanayagam Charumathi
- Sachdev Harshpal S.
- Safiri Saeid
- Saidi Olfa
- Salanave Benoit
- Salazar-Martinez Eduardo
- Salmeron Diego
- Salomaa Veikko
- Salonen Jukka T.
- Salvetti Massimo
- Sanchez-Abanto Jose
- Sandjaja Sandjaja
- Sandra Ruiz-Betancourt Blanca
- Sans Susana
- Sant'Angelo Victoria Farrugia
- Santa-Marina Loreto
- Santos Sanz Sara
- Santos Silva Diego Augusto
- Santos Diana A.
- Santos Ina S.
- Santos Osvaldo
- Santos Rute
- Saramies Jouko L.
- Sardinha Luis B.
- Sarrafzadegan Nizal
- Saum Kai-Uwe
- Savin Stefan
- Savva Savvas
- Savy Mathilde
- Scazufca Marcia
- Schargrodsky Herman
- Schienkiewitz Anja
- Schindler Karin
- Schipf Sabine
- Schmidt Carsten O.
- Schmidt Ida Maria
- Schoettker Ben
- Schultsz Constance
- Schutte Aletta E.
- Sebert Sylvain
- Sein Aye Aye
- Selamat Rusidah
- Sember Vedrana
- Sen Abhijit
- Senbanjo Idowu O.
- Sepanlou Sadaf G.
- Sequera Victor
- Serra-Majem Luis
- Servais Jennifer
- Shalnova Svetlana A.
- Sharma Sanjib K.
- Shaw Jonathan E.
- Shengelia Lela
- Shibuya Kenji
- Shimizu-Furusawa Hana
- Shin Dong Wook
- Shin Youchan
- Si-Ramlee Khairil
- Siani Alfonso
- Siantar Rosalynn
- Sibai Abla M.
- Silva Antonio M.
- Simon Mary
- Simons Judith
- Simons Leon A.
- Sjoberg Agneta
- Sjostrom Michael
- Slowikowska-Hilczer Jolanta
- Slusarczyk Przemyslaw
- Smeeth Liam
- Snijder Marieke B.
- So Hung-Kwan
- Sobngwi Eugene
- Soderberg Stefan
- Soekatri Moesijanti Y. E.
- Soemantri Agustinus
- Solfrizzi Vincenzo
- Solomon Bethlehem D.
- Son Thai Pham Son Thai Pham
- Sonestedt Emily
- Song Yi
- Sophiea Marisa K.
- Sorensen Thorkild I. A.
- Soric Maroje
- Soumare Aicha
- Spinelli Angela
- Spiroski Igor
- Staessen Jan A.
- Stamm Hanspeter
- Starc Gregor
- Stathopoulou Maria G.
- Staub Kaspar
- Stavreski Bill
- Steene-Johannessen Jostein
- Stehle Peter
- Stein Aryeh D.
- Stergiou George S.
- Stessman Jochanan
- Stevens Gretchen A.
- Stocks Tanja
- Stoeckl Doris
- Stokwiszewski Jakub
- Stratton Gareth
- Stronks Karien
- Strufaldi Maria Wany
- Sturua Lela
- Suarez-Medina Ramon
- Sun Chien-An
- Sundstrom Johan
- Sung Yn-Tz
- Sunyer Jordi
- Suriyawongpaisal Paibul
- Swinburn Boyd A.
- Sy Rody G.
- Sylva Rene Charles
- Szponar Lucjan
- Taddei Cristina
- Tai Hing Lam Tai Hing Lam
- Tai E. Shyong
- Tammesoo Mari-Liis
- Tamosiunas Abdonas
- Tan Eng Joo
- Tang Xun
- Tanser Frank
- Tao Yong
- Tarawneh Mohammed Rasoul
- Tarp Jakob
- Tarqui-Mamani Carolina B.
- Taylor Anne
- Tchibindat Felicite
- Tebar William R.
- Tell Grethe
- Tello Tania
- Theobald Holger
- Theodoridis Xenophon
- Thijs Lutgarde
- Thuesen Betina H.
- Ticha Lubica
- Timmermans Erik J.
- Tjonneland Anne
- Tolonen Hanna K.
- Tolstrup Janne S.
- Topbas Murat
- Topor-Madry Roman
- Tormo Maria Jose
- Tornaritis Michael J.
- Torrent Maties
- Toselli Stefania
- Traissac Pierre
- Tran Quoc Bao Tran Quoc Bao
- Trichopoulos Dimitrios
- Trichopoulou Antonia
- Trinh Oanh T. H.
- Trivedi Atul
- Tsao Yu-Hsiang
- Tshepo Lechaba
- Tsigga Maria
- Tsugane Shoichiro
- Tulloch-Reid Marshall K.
- Tullu Fikru
- Tuomainen Tomi-Pekka
- Tuomilehto Jaakko
- Turley Maria L.
- Tynelius Per
- Tzotzas Themistoklis
- Tzourio Christophe
- Ueda Peter
- Ugel Eunice E.
- Ukoli Flora A. M.
- Ulmer Hanno
- Unal Belgin
- Uusitalo Hannu M. T.
- Vaitkeviciute Justina
- Valdivia Gonzalo
- Vale Susana
- Valvi Damaskini
- van der Schouw Yvonne T.
- Van Herck Koen
- van Rossem Lenie
- Van Schoor Natasja M.
- van Valkengoed Irene G. M.
- Vanderschueren Dirk
- Vanuzzo Diego
- Varela-Moreiras Gregorio
- Varona-Perez Patricia
- Vatten Lars
- Vega Tomas
- Veidebaum Toomas
- Velasquez-Melendez Gustavo
- Velika Biruta
- Veronesi Giovanni
- Verschuren W. M. Monique
- Victora Cesar G.
- Viegi Giovanni
- Viet Lucie
- Vineis Paolo
- Vioque Jesus
- Virtanen Jyrki K.
- Visser Marjolein
- Visvikis-Siest Sophie
- Viswanathan Bharathi
- Vlasoff Tiina
- Vollenweider Peter
- Volzke Henry
- Voutilainen Ari
- Voutilainen Sari
- Vrijheid Martine
- Vrijkotte Tanja G. M.
- Vrkic Tajana Zeljkovic
- Wade Alisha N.
- Wagner Aline
- Waldhoer Thomas
- Walton Janette
- Wanderley Rildo S., Jr.
- Wang Ming-Dong
- Wang Qian
- Wang Xiangjun
- Wang Ya Xing
- Wang Ying-Wei
- Wannamethee S. Goya
- Wareham Nicholas
- Weber Adelheid
- Weerasekera Deepa
- Weghuber Daniel
- Wei Wenbin
- Whincup Peter H.
- Widhalm Kurt
- Widyahening Indah S.
- Wiecek Andrzej
- Wijga Alet H.
- Wilks Rainford J.
- Willeit Johann
- Willeit Peter
- Wilsgaard Tom
- Wojtyniak Bogdan
- Wong Jyh Eiin
- Wong Norazizah Ibrahim
- Wong Tien Yin
- Wong-McClure Roy A.
- Woo Jean
- Woodward Mark
- Wu Frederick C.
- Wu Jianfeng
- Wu Shouling
- Xu Haiquan
- Xu Liang
- Yamborisut Uruwan
- Yan Weili
- Yang Ling
- Yang Xiaoguang
- Yang Yang
- Yardim Nazan
- Yaseri Mehdi
- Ye Xingwang
- Yiallouros Panayiotis K.
- Yngve Agneta
- Yoosefi Moein
- Yoshihara Akihiro
- You Qi Sheng
- You San-Lin
- Younger-Coleman Novie O.
- Yusof Safiah Md
- Yusoff Ahmad Faudzi
- Yusoff Muhammad Fadhli Mohd
- Zaccagni Luciana
- Zafiropulos Vassilis
- Zainuddin Ahmad A.
- Zamani Farhad
- Zambon Sabina
- Zampelas Antonis
- Zamrazilova Hana
- Zapata Maria Elisa
- Zaw Ko Ko
- Zdrojewski Tomasz
- Zeng Yi
- Zhao Dong
- Zhao Wenhua
- Zheng Wei
- Zheng Yingfeng
- Zholdin Bekbolat
- Zhou Bin
- Zhou Maigeng
- Zhu Dan
- Zhussupov Baurzhan
- Zimmermann Esther
- Zuniga Cisneros Julio
- Publication venue
- Publication date
- 01/01/2019
- Field of study
Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities(.)(1,2) This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity(3-6). Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean BMI segregated by place of residence (a rural or urban area) from 1985 to 2017. We show that, contrary to the dominant paradigm, more than 55% of the global rise in mean BMI from 1985 to 2017-and more than 80% in some low- and middle-income regions-was due to increases in BMI in rural areas. This large contribution stems from the fact that, with the exception of women in sub-Saharan Africa, BMI is increasing at the same rate or faster in rural areas than in cities in low- and middle-income regions. These trends have in turn resulted in a closing-and in some countries reversal-of the gap in BMI between urban and rural areas in low- and middle-income countries, especially for women. In high-income and industrialized countries, we noted a persistently higher rural BMI, especially for women. There is an urgent need for an integrated approach to rural nutrition that enhances financial and physical access to healthy foods, to avoid replacing the rural undernutrition disadvantage in poor countries with a more general malnutrition disadvantage that entails excessive consumption of low-quality calories.Peer reviewe
Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants
- Author
- Abarca-Gomez Leandra
- Abdeen Ziad A
- Abdrakhmanova Shynar
- Abu-Rmeileh Niveen M
- Acosta-Cazares Benjamin
- Adams Robert J
- Aekplakorn Wichai
- Afsana Kaosar
- Afzal Shoaib
- Agdeppa Imelda A
- Aghazadeh-Attari Javad
- Aguilar-Salinas Carlos A
- Agyemang Charles
- Ahmad Mohamad Hasnan
- Ahmad Noor Ani
- Ahmadi Ali
- Ahmadi Naser
- Ahmed Soheir H
- Ahrens Wolfgang
- Aitmurzaeva Gulmira
- Ajlouni Kamel
- Al Nsour Mohannad
- Al-Hazzaa Hazzaa M
- Al-Othman Amani Rashed
- Al-Raddadi Rajaa
- Alarouj Monira
- AlBuhairan Fadia
- AlDhukair Shahla
- Ali Mohamed M
- Alkandari Abdullah
- Alkerwi Ala'a
- Allin Kristine
- Alvarez-Pedrerol Mar
- Aly Eman
- Amarapurkar Deepak N
- Amiri Parisa
- Amougou Norbert
- Amouyel Philippe
- Andersen Lars Bo
- Anderssen Sigmund A
- Angquist Lars
- Anjana Ranjit Mohan
- Ansari-Moghaddam Alireza
- Aounallah-Skhiri Hajer
- Araujo Joana
- Ariansen Inger
- Aris Tahir
- Arku Raphael E
- Arlappa Nimmathota
- Aryal Krishna K
- Aspelund Thor
- Assah Felix K
- Assuncao Maria Cecilia F
- Aung May Soe
- Auvinen Juha
- Avdicova Maria
- Azevedo Ana
- Azimi-Nezhad Mohsen
- Azizi Fereidoun
- Azmin Mehrdad
- Babu Bontha V
- Baharudin Azli
- Bahijri Suhad
- Baker Jennifer L
- Balakrishna Nagalla
- Bamoshmoosh Mohamed
- Banach Maciej
- Bandosz Piotr
- Banegas Jose R
- Baran Joanna
- Barbagallo Carlo M
- Barcelo Alberto
- Barkat Amina
- Barros Aluisio JD
- Barros Mauro Virgilio Gomes
- Basit Abdul
- Bastos Joao Luiz D
- Bata Iqbal
- Batieha Anwar M
- Batista Rosangela L
- Battakova Zhamilya
- Batyrbek Assembekov
- Baur Louise A
- Beaglehole Robert
- Bebakar Wan Mohamad Wan
- Bel-Serrat Silvia
- Belavendra Antonisamy
- Ben Romdhane Habiba
- Benedics Judith
- Benet Mikhail
- Bennett James E
- Bennett James E
- Bentham James
- Bergh Ingunn Holden
- Berkinbayev Salim
- Bernabe-Ortiz Antonio
- Bernotiene Gailute
- Bettiol Heloisa
- Bezerra Jorge
- Bhagyalaxmi Aroor
- Bharadwaj Sumit
- Bhargava Santosh K
- Bhutta Zulfiqar A
- Bhutta Zulfiqar A
- Bi Hongsheng
- Bi Yufang
- Bia Daniel
- Bikbov Mukharram M
- Bista Bihungum
- Bixby Honor
- Bjelica Dusko J
- Bjerregaard Peter
- Bjertness Espen
- Bjertness Marius B
- Bjorkelund Cecilia
- Black Robert
- Bloch Katia V
- Blokstra Anneke
- Bo Simona
- Bobak Martin
- Boddy Lynne M
- Boehm Bernhard O
- Boeing Heiner
- Boggia Jose G
- Bogova Elena
- Boissonnet Carlos P
- Bojesen Stig E
- Boker Lital Keinan
- Bonaccio Marialaura
- Bongard Vanina
- Bonilla-Vargas Alice
- Bopp Matthias
- Borghs Herman
- Bovet Pascal
- Braeckevelt Lien
- Braeckman Lutgart
- Bragt Marjolijn CE
- Brajkovich Imperia
- Branca Francesco
- Braunerova Radka Taxova
- Breckenkamp Juergen
- Breda Joao
- Brenner Hermann
- Brewster Lizzy M
- Brian Garry R
- Brinduse Lacramioara
- Brophy Sinead
- Bruno Graziella
- Bueno-de-Mesquita H Bas
- Bugge Anna
- Buoncristiano Marta
- Burazeri Genc
- Burns Con
- Cacciottolo Joseph
- Cadena Leticia Hernandez
- Cai Hui
- Cama Tilema
- Cameron Christine
- Camolas Jose
- Can Gunay
- Candido Ana Paula C
- Canete Felicia
- Capanzana Mario V
- Capkova Nadezda
- Capuano Eduardo
- Capuano Vincenzo
- Cardol Marloes
- Cardoso Viviane C
- Carlsson Axel C
- Carmuega Esteban
- Carrillo-Larco Rodrigo M
- Carvalho Joana
- Casajus Jose A
- Casanueva Felipe F
- Celikcan Ertugrul
- Censi Laura
- Cervantes-Loaiza Marvin
- Cesar Juraci A
- Chamukuttan Snehalatha
- Chan Angelique W
- Chan Queenie
- Chaturvedi Himanshu K
- Chaturvedi Nish
- Chen Chien-Jen
- Chen Fangfang
- Chen Huashuai
- Chen Shuohua
- Chen Zhengming
- Cheng Ching-Yu
- Cheraghian Bahman
- Chetrit Angela
- Chikova-Iscener Ekaterina
- Chinh Nguyen Huu
- Chiolero Arnaud
- Chiou Shu-Ti
- Chirita-Emandi Adela
- Chirita-Emandi Adela
- Chirlaque Maria-Dolores
- Cho Belong
- Christensen Kaare
- Christofaro Diego G
- Chudek Jerzy
- Cifkova Renata
- Cilia Michelle
- Cinteza Eliza
- Cisneros Julio Zuniga
- Claessens Frank
- Clarke Janine
- Clays Els
- Cohen Emmanuel
- Concin Hans
- Confortin Susana C
- Cooper Cyrus
- Coppinger Tara C
- Corpeleijn Eva
- Costanzo Simona
- Cottel Dominique
- Cowan Melanie J
- Cowell Chris
- Craig Cora L
- Crampin Amelia C
- Crujeiras Ana B
- Csilla Semanova
- Cucu Alexandra M
- Cui Liufu
- Cureau Felipe V
- D'Arrigo Graziella
- d'Orsi Eleonora
- da Silva Bruna Goncalves Cordeiro
- Dacica Liliana
- Dallongeville Jean
- Damasceno Albertino
- Damsgaard Camilla T
- Danaei Goodarz
- Danaei Goodarz
- Dankner Rachel
- Dantoft Thomas M
- Dasgupta Parasmani
- Dastgiri Saeed
- Dauchet Luc
- Davletov Kairat
- De Backer Guy
- De Bacquer Dirk
- de Gaetano Giovanni
- De Henauw Stefaan
- de Leon Antonio Cabrera
- de Oliveira Paula Duarte
- de Paiva Karina Mary
- De Ridder David
- De Ridder Karin
- de Rooij Susanne R
- De Smedt Delphine
- de Souza Rildo
- de Wit Tobias F Rinke
- Deepa Mohan
- Deev Alexander D
- DeGennaro Vincent
- Dehghan Abbas
- Delisle Helene
- Delpeuch Francis
- Demarest Stefaan
- Dennison Elaine
- Deren Katarzyna
- Deschamps Valerie
- Dhana Klodian
- Dhimal Meghnath
- Di Castelnuovo Augusto F
- Di Cesare Mariachiara
- Dias-da-Costa Juvenal Soares
- Diaz Alejandro
- Diaz-Sanchez Maria Elena
- Dika Zivka
- Djalalinia Shirin
- Djordjic Visnja
- Do Ha TP
- Dobson Annette J
- Donati Maria Benedetta
- Donfrancesco Chiara
- Donoso Silvana P
- Doring Angela
- Dorobantu Maria
- Dorosty Ahmad Reza
- Doua Kouamelan
- Drygas Wojciech
- Duan Jia Li
- Duante Charmaine A
- Duboz Priscilla
- Duda Rosemary B
- Duleva Vesselka
- Dulskiene Virginija
- Dumith Samuel C
- Dushpanova Anar
- Dzerve Vilnis
- Dziankowska-Zaborszczyk Elzbieta
- Eddie Ricky
- Eftekhar Ebrahim
- Egbagbe Eruke E
- Eggertsen Robert
- Eghtesad Sareh
- Eiben Gabriele
- Ekelund Ulf
- El Ati Jalila
- El-Khateeb Mohammad
- Eldemire-Shearer Denise
- Eliasen Marie
- Elliott Paul
- Engle-Stone Reina
- Enguerran Macia
- Erasmus Rajiv T
- Erbel Raimund
- Erem Cihangir
- Eriksen Louise
- Eriksson Johan G
- Escobedo-de la Pena Jorge
- Eslami Saeid
- Esmaeili Ali
- Evans Alun
- Ezzati Majid
- Faeh David
- Fakhretdinova Albina A
- Fall Caroline H
- Faramarzi Elnaz
- Farjam Mojtaba
- Farzadfar Farshad
- Fattahi Mohammad Reza
- Fawwad Asher
- Felix-Redondo Francisco J
- Ferguson Trevor S
- Fernandes Romulo A
- Fernandez-Berges Daniel
- Ferrante Daniel
- Ferrao Thomas
- Ferrari Marika
- Ferrario Marco M
- Ferreccio Catterina
- Ferrer Eldridge
- Ferrieres Jean
- Figueiro Thamara Hubler
- Fijalkowska Anna
- Fink Gunther
- Fischer Krista
- Foger Bernhard
- Foo Leng Huat
- Forsner Maria
- Fouad Heba M
- Francis Damian K
- Franco Maria do Carmo
- Franco Oscar H
- Frikke-Schmidt Ruth
- Frontera Guillermo
- Fuchs Flavio D
- Fuchs Sandra C
- Fujiati Isti I
- Fujita Yuki
- Fumihiko Matsuda
- Furusawa Takuro
- Gaciong Zbigniew
- Gafencu Mihai
- Galbarczyk Andrzej
- Galenkamp Henrike
- Galeone Daniela
- Galfo Myriam
- Galvano Fabio
- Gao Jingli
- Garba Jamila Abubakar
- Garcia-de-la-Hera Manoli
- Garcia-Solano Marta
- Gareta Dickman
- Garnett Sarah P
- Gaspoz Jean-Michel
- Gasull Magda
- Gaya Adroaldo Cesar Araujo
- Gaya Anelise Reis
- Gazzinelli Andrea
- Gehring Ulrike
- Geiger Harald
- Geleijnse Johanna M
- Ghaffar Suhaila Abdul
- Ghanbari Ali
- Ghasemi Erfan
- Gheorghe-Fronea Oana-Florentina
- Giampaoli Simona
- Gianfagna Francesco
- Gill Tiffany K
- Giovannelli Jonathan
- Gironella Glen
- Giwercman Aleksander
- Gkiouras Konstantinos
- Godos Justyna
- Gogen Sibel
- Goldsmith Rebecca A
- Goltzman David
- Gomez Santiago F
- Gomula Aleksandra
- Goncalves Helen
- Gonzalez Angel R
- Gonzalez-Chica David A
- Gonzalez-Gross Marcela
- Gonzalez-Leon Margot
- Gonzalez-Rivas Juan P
- Gonzalez-Villalpando Clicerio
- Gonzalez-Villalpando Maria-Elena
- Gottrand Frederic
- Graca Antonio Pedro
- Graff-Iversen Sidsel
- Grafnetter Dusan
- Grajda Aneta
- Grammatikopoulou Maria G
- Gregg Edward W
- Gregor Ronald D
- Grodzicki Tomasz
- Groholt Else Karin
- Grontved Anders
- Grosso Giuseppe
- Gruden Gabriella
- Gu Dongfeng
- Gualdi-Russo Emanuela
- Guallar-Castillon Pilar
- Gualtieri Andrea
- Gudmundsson Elias F
- Gudnason Vilmundur
- Guerrero Ramiro
- Guessous Idris
- Guimaraes Andre L
- Gulliford Martin C
- Gunnlaugsdottir Johanna
- Gunter Marc J
- Guo Xiu-Hua
- Guo Yin
- Gupta Prakash C
- Gupta Rajeev
- Gureje Oye
- Gurzkowska Beata
- Gutierrez Laura
- Gutierrez-Gonzalez Enrique
- Gutzwiller Felix
- Ha Seongjun
- Hadaegh Farzad
- Hadjigeorgiou Charalambos A
- Haghshenas Rosa
- Hakimi Hamid
- Halkjaer Jytte
- Hambleton Ian R
- Hamzeh Behrooz
- Hange Dominique
- Hanif Abu AM
- Hantunen Sari
- Hashemi-Shahri Seyed Mohammad
- Hassapidou Maria
- Hata Jun
- Haugsgjerd Teresa
- Hayes Alison J
- He Jiang
- He Yuan
- He Yuna
- Heidinger-Felso Regina
- Heinen Mirjam
- Hejgaard Tatjana
- Hendriks Marleen Elisabeth
- Henrique Rafael dos Santos
- Henriques Ana
- Herrala Sauli
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- Herter-Aeberli Isabelle
- Heshmat Ramin
- Hill Allan G
- Ho Sai Yin
- Ho Suzanne C
- Hoang Van Minh
- Hobbs Michael
- Hofman Albert
- Holdsworth Michelle
- Homayounfar Reza
- Homs Clara
- Hopman Wilma M
- Horimoto Andrea RVR
- Hormiga Claudia M
- Horta Bernardo L
- Houti Leila
- Howitt Christina
- Htet Aung Soe
- Htike Maung Maung Than
- Hu Yonghua
- Huerta Jose Maria
- Huhtaniemi Ilpo Tapani
- Husseini Abdullatif
- Huybrechts Inge
- Hwalla Nahla
- Hyska Jolanda
- Iacoviello Licia
- Ibarluzea Jesus M
- Ibrahim Mohsen M
- Ikeda Nayu
- Ikram M Arfan
- Ioannidou Eliza Markidou
- Iotova Violeta
- Irazola Vilma E
- Ishida Takafumi
- Islam Muhammad
- Islam Sheikh Mohammed Shariful
- Iurilli Maria LC
- Iwasaki Masanori
- Jackson Rod T
- Jacobs Jeremy M
- Jaddou Hashem Y
- Jafar Tazeen
- James Kenneth
- Jamil Kazi M
- Jamrozik Konrad
- Janszky Imre
- Janus Edward
- Jarani Juel
- Jarvelin Marjo-Riitta
- Jasienska Grazyna
- Jelakovic Ana
- Jelakovic Bojan
- Jennings Garry
- Jerome Charles Sossa
- Jha Anjani Kumar
- Jiang Chao Qiang
- Jimenez Ramon O
- Jockel Karl-Heinz
- Joffres Michel
- Johansson Mattias
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- Rahman Mahmudur
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- Rakhmatulloev Sherali
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- Ramachandran Ambady
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- Sandjaja
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- Slowikowska-Hilczer Jolanta
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- Smeeth Liam
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- Soares Fernanda Cunha
- Sobek Grzegorz
- Sobngwi Eugene
- Sodemann Morten
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- Soekatri Moesijanti YE
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- Sorensen Thorkild IA
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- Soric Maroje
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- Soumare Aicha
- Sovic Slavica
- Sparboe-Nilsen Bente
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- Stoyanova Ekaterina
- Stratton Gareth
- Stronks Karien
- Strufaldi Maria Wany
- Sturua Lela
- Suarez-Medina Ramon
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- Vanderschueren Dirk
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- Varela-Moreiras Gregorio
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- Wade Alisha N
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- Wambiya Elvis OA
- Wang Ming-Dong
- Wang Ningli
- Wang Qian
- Wang Xiangjun
- Wang Ya Xing
- Wang Ying-Wei
- Wannamethee S Goya
- Wareham Nicholas
- Weber Adelheid
- Wedderkopp Niels
- Weerasekera Deepa
- Weghuber Daniel
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- Widhalm Kurt
- Widyahening Indah S
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- Willeit Johann
- Willeit Peter
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- Wong Tien Yin
- Wong-McClure Roy A
- Woo Jean
- Woodward Mark
- Wu Frederick C
- Wu Jianfeng
- Wu Li Juan
- Wu Shouling
- Xu Haiquan
- Xu Liang
- Yaacob Nor Azwany
- Yamborisut Uruwan
- Yan Weili
- Yang Ling
- Yang Xiaoguang
- Yang Yang
- Yardim Nazan
- Yaseri Mehdi
- Yasuharu Tabara
- Ye Xingwang
- Yiallouros Panayiotis K
- Yoosefi Moein
- Yoshihara Akihiro
- You Qi Sheng
- You San-Lin
- Younger-Coleman Novie O
- Yusof Safiah Md
- Yusoff Ahmad Faudzi
- Yusoff Muhammad Fadhli Mohd
- Zaccagni Luciana
- Zafiropulos Vassilis
- Zainuddin Ahmad A
- Zainuddin Ahmad A
- Zakavi Seyed Rasoul
- Zamani Farhad
- Zambon Sabina
- Zampelas Antonis
- Zamrazilova Hana
- Zapata Maria Elisa
- Zargar Abdul Hamid
- Zaw Ko Ko
- Zdrojewski Tomasz
- Zeng Yi
- Zhang Luxia
- Zhang Zhen-Yu
- Zhao Dong
- Zhao Ming-Hui
- Zhao Wenhua
- Zhen Shiqi
- Zheng Wei
- Zheng Yingfeng
- Zholdin Bekbolat
- Zhou Bin
- Zhou Maigeng
- Zhu Dan
- Zocalo Yanina
- Zuziak Monika
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2020
- Field of study
Summary Background Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents. Methods For this pooled analysis, we used a database of cardiometabolic risk factors collated by the Non-Communicable Disease Risk Factor Collaboration. We applied a Bayesian hierarchical model to estimate trends from 1985 to 2019 in mean height and mean BMI in 1-year age groups for ages 5–19 years. The model allowed for non-linear changes over time in mean height and mean BMI and for non-linear changes with age of children and adolescents, including periods of rapid growth during adolescence. Findings We pooled data from 2181 population-based studies, with measurements of height and weight in 65 million participants in 200 countries and territories. In 2019, we estimated a difference of 20 cm or higher in mean height of 19-year-old adolescents between countries with the tallest populations (the Netherlands, Montenegro, Estonia, and Bosnia and Herzegovina for boys; and the Netherlands, Montenegro, Denmark, and Iceland for girls) and those with the shortest populations (Timor-Leste, Laos, Solomon Islands, and Papua New Guinea for boys; and Guatemala, Bangladesh, Nepal, and Timor-Leste for girls). In the same year, the difference between the highest mean BMI (in Pacific island countries, Kuwait, Bahrain, The Bahamas, Chile, the USA, and New Zealand for both boys and girls and in South Africa for girls) and lowest mean BMI (in India, Bangladesh, Timor-Leste, Ethiopia, and Chad for boys and girls; and in Japan and Romania for girls) was approximately 9–10 kg/m2. In some countries, children aged 5 years started with healthier height or BMI than the global median and, in some cases, as healthy as the best performing countries, but they became progressively less healthy compared with their comparators as they grew older by not growing as tall (eg, boys in Austria and Barbados, and girls in Belgium and Puerto Rico) or gaining too much weight for their height (eg, girls and boys in Kuwait, Bahrain, Fiji, Jamaica, and Mexico; and girls in South Africa and New Zealand). In other countries, growing children overtook the height of their comparators (eg, Latvia, Czech Republic, Morocco, and Iran) or curbed their weight gain (eg, Italy, France, and Croatia) in late childhood and adolescence. When changes in both height and BMI were considered, girls in South Korea, Vietnam, Saudi Arabia, Turkey, and some central Asian countries (eg, Armenia and Azerbaijan), and boys in central and western Europe (eg, Portugal, Denmark, Poland, and Montenegro) had the healthiest changes in anthropometric status over the past 3·5 decades because, compared with children and adolescents in other countries, they had a much larger gain in height than they did in BMI. The unhealthiest changes—gaining too little height, too much weight for their height compared with children in other countries, or both—occurred in many countries in sub-Saharan Africa, New Zealand, and the USA for boys and girls; in Malaysia and some Pacific island nations for boys; and in Mexico for girls. Interpretation The height and BMI trajectories over age and time of school-aged children and adolescents are highly variable across countries, which indicates heterogeneous nutritional quality and lifelong health advantages and risks
Streptococcus agalactiae in Brazil: serotype distribution, virulence determinants and antimicrobial susceptibility
- Author
- A Dmitriev
- A Schuchat
- ABA Corrêa
- ABA Corrêa
- Alessandra FA de Bastos
- Ana A Araujo
- Ana Caroline N Botelho
- André N Olendzki
- B Dogan
- Camila Marconi
- CDC- Centers for Disease Control and Prevention
- Cicero AG Dias
- CJ Baker
- Cleuber F Fontes
- CLSI
- CR Phares
- E Culebras
- E Kim
- EC João
- Eddie FC Murta
- Efigênia LT de Amorin
- ER Martins
- ER Martins
- ES Otaguiri
- G Gherardi
- Gianni O Santos
- H Grundmann
- HC Maisey
- HC Slotved
- J Sutcliffe
- JA Simões
- JJ Gonzalez
- JK Palmeiro
- JL Andrews
- Jussara K Palmeiro
- K Kimura
- K Trzcinski
- Kedma Magalhães
- LC Benchetrit
- Libera M Dalla-Costa
- Lilian F Paffadore
- LM Teixeira
- Lúcia M Teixeira
- M Desjardins
- MA Martinez
- Marco Andrey
- Maria SG Raddi
- MC Roberts
- Meireille ÂB Sousa
- N Nagano
- P Pillai
- PAM Nakamura
- Patricia CS Ribeiro
- Paulo C Fernandes Jr
- Penélope S Marinho
- PR Hsush
- PR Hunter
- Rita BG Bornia
- Rosemary Santos
- RS Duarte
- S Dahesh
- S-L Luan
- SM Borchardt
- Sérgio Eduardo L Fracalanzza
- Tatiana CA Pinto
- TCA Pinto
- TH Skoff
- Valéria MN Alves
- Vanusa G Dutra
- VC Souza
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
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- Vochin Ana
- Volta Carlo Alberto
- von der Osten Ingrid
- Von Der Osten Ingrid
- von Lewinski Dirk
- Vosylius Saulius
- Vuković Anita
- Vullum Sylvi
- Vymazal Tamas
- Vymazal Tomas
- Wahab Sherliza
- Wahlbom Ewa
- Waibel Hansjoerg
- Wallin Ewa
- Walsh Amy
- Wan Jianhong
- Wan Yan
- Wang Damei
- Wang Fanglan
- Wang GuoXian
- Wang Hai Yun
- Wang Haiyan
- Wang Jing
- Wang Kefang
- Wang LingLing
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- Wang Shuo
- Wang Wei
- Wang Wenmei
- Wang Xiaomin
- Wang Yan
- Wang Ying
- Wang Yingli
- Wang Yuping
- Wang Yuxia
- Watts Stacey
- Waweru-Siika Wangari
- Wei Dongfang
- Wei Wei
- Wei Xiyan
- Wei Ying
- Welters Ingeborg D.
- White Joanne
- White Nigel
- Whiteley Simon
- Whitticase Richard
- Wiborg Elisabeth
- Wijnands Patricia
- Wilby Liz
- Williams Anne
- Williams Ged
- Williams Helen
- Williams Karen
- Williams Lynne
- Wilting Rob
- Wise Robert
- Woods Justin
- Wright Kerry
- Wu Juan
- Wu ShiFen
- Wu Xiaojun
- Wu Xiaoying
- Wu Yang
- Wu Yun
- Wu Zijing
- Xhindi Nordian
- Xia Chun Jie
- Xia Xinhua
- Xiao Lina
- Xiao Min
- Xiao Yan
- Xiaoyan Yang
- Xie Yan
- Xing Cynthia
- Xiong Yunfeng
- Xixi Li
- Xu Lina
- Xu Xiao
- Xu Xuelian
- Xu Yan
- Xue Xiujuan
- Yaghi Aktham
- Yakubu Yakubu H.
- Yamamoto Ryohey
- Yan Howe
- Yan Xiaoli
- Yan Yan
- Yang Fan
- Yang Fengling
- Yang Huai
- Yang Jing
- Yang Lei
- Yang Qiao
- Yang Shunzhu
- Yang Yanping
- Yang YongXia
- Yao Xiuying
- Yao Yanlan
- Yao Zhiru
- Ye Man
- Ye Mei
- Yeni Nomhle Princess
- Yeon-Joo Lee
- Yildiz İsmail
- Yilmaz Hakan
- Yin Hai
- Yin Li
- Young Charlotte
- Young-Jae Cho
- Yu Jing
- Yu Min
- Yu Tingting
- Yu Zhu Jun
- Yuan Cui
- Yuan Weilian
- Yuan Yuxia
- Yuchen Wu
- Yuemen Ly
- Yumei Chen
- Zahra Hajer Ben
- Zainudin Asmah
- Zakalik Graciela
- Zaki Ahmed
- Zalba-Etayo Begoña
- Zamora Purificacion Sanchez
- Zamorano Matias Jesús Flamm
- Zan Tao
- Zand Farid
- Zarei Fatemeh
- Zeng Jing Mei
- Zeng Qi
- Zepoy Sofia
- Zerman Avşar
- Zermeno Jorge Macias
- Zgrzheblovska Lesia
- Zhang Aizhi
- Zhang Baoke
- Zhang Feifei
- Zhang Guiping
- Zhang Hong
- Zhang Hongsu
- Zhang Hui
- Zhang Jing
- Zhang Jundi
- Zhang Libing
- Zhang Ling
- Zhang Na
- Zhang Wei
- Zhang Yali
- Zhang Ying
- Zhang Zhenxia
- Zhao Hui Min
- Zhao Lijuan
- Zhao Lina
- Zhao Qian
- Zhao Qingli
- Zhao Rong Hua
- Zhao Ronghua
- Zhao Wenwen
- Zhao Yingjuan
- Zhedaeva Marina
- Zheng Hong
- Zheng Jing
- Zheng Xianhong
- Zhigang Zhang
- Zhijuan Wang
- Zhiping Sun
- Zhivotneva Trina
- Zhou Yuming
- Zhu Guoyan
- Zhu JiFen
- Zhu Jin Yu
- Zivanovic-Posilovic Gordana
- Zorko Nika
- Zubareva Nadezhda
- Zuev Evgeniy
- Zueva Oksana
- Zulkifli Zulkifli
- Ágoston Zsuzsann
- Åkerman Eva
- Çelik Jale Bengi
- Ñamendys-Silva Silvio A.
- Özcan Beysim
- Özserezli Boğaç
- Ünlü Nurdan
- Čuljak Hemena
- Şentürk Evren
- Šuput Aleksandar
- Publication venue
- 'Organisation for Economic Co-Operation and Development (OECD)'
- Publication date
- 26/02/2021
- Field of study
Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat
Recommended from our members
Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
- Author
- Abdala Antonio
- Abidi Khalid
- Abillama Fayez François
- Abos Francisco Javier Saenz
- Aboufray Ahmed Ali
- Abregal Giancarlo
- Abroug Fekri
- Achilleos Eleni
- Acosta Ysica
- Adam Višnja Nesek
- Adamina Ileana
- Adams John
- Adamuz Jordi
- Adejumo Prisca Olabisi
- Adekola Oyebola
- Ademokun Jane
- Adenekan Anthony
- Adib Nik Azman Nik
- Adipa Faustina Excel
- Afonso Elsa
- Aganon Ferdinand
- Agarwal Sonika
- Aguirre Joaquin
- Aguirre Lydia Gallego
- Aguirre-Bermeo Hernan
- Ahmad Fatima Kasem El
- Ahmad Meraj
- Ahmed Hazem
- Ahn Jong-Joon
- Ahtiala Maarit
- Akbas Turkay
- Akdağ Devrim
- Akker Mustafa
- Akselsen Gro Ringstad
- Al-Alawi Maram Milud Said
- Alabuzidi Aya
- Alampi Daniela
- Albaiceta Guillermo Muñiz
- Albert Patricia
- Albrecht Lea
- Albrett Jonathan
- Alexandropoulou Paraskevi
- Alexandrou Anna
- Ali Ashwaq
- Ali Mohd Nazri
- Alias Anita
- Alkhumsi Soad Imhmed R.
- Allaert Silvie
- Allison Nicola
- Almekhlafi Ghaleb
- Alonso Helena Fernandez
- Alsheikhly Ahmed Subhy
- Alshrif Abdualhamid I
- Alvarenga Gloria
- Alvarez Diana
- Alvarez Gonzalo Martín
- Alvarez Gustavo Andres
- Alvarez Jorge Duerto
- Alvarez Josep Trenado
- Alvarez Raquel Garcia
- Alves Paulo
- Andersen Marit Hildegunn
- Andersen Yvonne
- Andresen Hanne
- Anisoglou Souzana
- Antonio Maria Gracia San
- Antunes Nelson
- Anvelt Eneli
- Aperocho Cristal April Jane
- Aponte Cesar
- Araya Paola
- Arcas María Luisa Bravo
- Arikan Huseyin
- Arntsen Wenche
- Arteta Arteta Donaldo S.
- Ashour Firas
- Assiri Amer
- Atchade Enora
- Ateya Zainab
- Attwood Ben
- Aucapina Alejandra
- Avalos Fernando
- Aves Emma
- Avogadro Prune
- Avramopoulou Lamprini
- Ay Mustafa
- Ay Serap Avcı
- Aya Umeda
- Ayala Maria
- Aydemir Semih
- Aydin Demet Tok
- Azencot Mazal
- Azoia Joao
- Baasanjav Battsetseg
- Babych Volodymyr
- Baccaro Fernando
- Badariotti Gustavo
- Bae Jung-Min
- Baek Jonghyun
- Baftiu Nehat
- Bagshaw Sean
- Bahrin Laila Kamaliah Kamalul
- Bai Dongmei
- Bai Xiaowu
- Baini Matías
- Bakas Apostolos
- Baker Helen
- Baker Nerilee
- Balasubramanian Madhu
- Balbay Abidin Oner
- Balon Sandrine
- Bantar Ana
- Banwarie Preveen
- Bao Guijun
- Baptiste-Savoie Jacqueline
- Barakat-Johnson Michelle
- Barefield Cindy
- Barkas Diane
- Barnes Christopher
- Barone Antonio
- Baronia Arvind
- Barr Louise
- Barreiro Emma Moreno
- Barros Elaine
- Barrowcliffe Suzanne
- Barrueco-Francioni Jesus Emilio
- Bartoli Julio Ricardo
- Baruah Rosaleen
- Bascary Carlos Alejandro
- Baskakov Danil
- Baskoro Windu
- Bastani Styliani
- Baumber Rachel
- Baxter Karen
- Bayraktar Yesim Serife
- Bealer Cheryl
- Bean Sarah
- Becker Cathy
- Becker Delmiro
- Behan Helena
- Beker Tatjana
- Bekos Vasileios
- Belii Adrian
- Belkhair Wesal Ali
- Belskiy Vladislav
- Ben-Hamouda Nawfel
- Ben-Jacob Talia
- Benbenishty Julie
- Bench Suzanne
- Bendelari Valentina
- Benlamin Mohamed
- Berry Gillian
- Bertoletti Fernando Pablo
- Besbes Lamia
- Besbes Lamia Ouanes
- Besch Guillaume
- Bestle Morten
- Beuret Pascal
- Bhakhtiani Lakshay
- Bhargava Vaibhav
- Bi AiPing
- Bianchini Suzana
- Bielskute Egidija
- Bilawicz Jan
- Binda Filipo
- Birgisdottir Hrönn
- Birgisdóttir Hrönn
- Bispo Bruno Miguel
- Biston Patrick
- Bjorgen Hege
- Blackwood Bronagh
- Blanc Agnès
- Blanco Daniel
- Blanco Maria Pilar Sogues
- Blasco Maria Luisa
- Bliksted Inger Abildgaard
- Blondal Asbjorn
- Bloos Frank
- Blot Stijn I.
- Bo Qi
- Bocui Nie
- Boedjawan Naraindath N.
- Bogarin Javier
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- Pelz Sabrina
- Pena José Manuel Garcia
- Peratoner Alberto
- Pereira Jorge
- Perez Hugo
- Perez-Torres David
- Perez-Vacas Jonathan
- Perme Janja
- Peterson Jessica
- Petosic Antonija
- Petrisor Cristina
- Petrushin Maxim
- Pečenković Suzana
- Philippart François
- Piergentili Federica
- Pili-Floury Sébastien
- Pillard Cindy
- Pineda Ana Alícia Velarde
- Pinheiro Cristiana Mota
- Pinto Susana
- Pinto Vitor Manuel Vaz
- Piradov Michael
- Pires Filpe
- Pivkina Alexandra
- Piza Petr
- Piñan Isabel Santín
- Plantefève Gaëtan
- Pleitinckx Vincianne
- Polgarova Petra
- Polo Ana Belén Curto
- Popescu Mihai
- Popescu Monica
- Potestio Christopher
- Powell Madeleine
- Preda Gabriel
- Prol-Silva Estefanía
- Prowle John
- Psarulis Konstantinos
- Pulak Paul
- Pulletz Mark
- Putruele Sofia
- Qawasmeh Khaled Al
- Qiao Hongmei
- Quagliotto Catia
- Quaini Attilio
- Quintard Hervé
- Quiroga Cristian
- Rabarova Daria
- Radavidson Anthony
- Radivojevic Renata Curic
- Rahim Azmin Huda Abdul
- Raimondo Arena
- Raitsiou Bogdan
- Raizman Rose
- Raj Ashok Sundai
- Rajendran Ajitha
- Rajković Marija
- Ramaker Bart
- Ramalho Aline
- Ramirez Mario
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- Ran Qiong
- Ranalli Flavia
- Randell Claire
- Rapley Jackie
- Rastegar Touraj
- Ratnam Shanthi
- Ratnam Shanti
- Ravani Ifigenia
- Reece-Anthony Rosie
- Reidinga Auke
- Reijntjens Jennifer
- Remor Natalie
- Ren Aiua
- Reyes Amylkar Garay
- Reyes Amylkar José Garay
- Reyes Laura Martinez
- Reyes Paul Eric
- Reynolds Claire
- Ribas Antoni Margarit
- Ribas Antonio Margarit
- Riera Alba
- Riessen Reimer
- Ringdal Mona
- Rinket Martin
- Ripolles-Melchor Javier
- Rita Clara Santa
- Rivas Juan Carlos
- Rivas Noelia
- Riveiro Marilyn
- Rizzo Antonino
- Rocco Monica
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- Rodriguez Gabriel Enrique
- Rojas-Suarez José
- Rokosh Ella
- Roller Martin
- Roman-Pognuz Erik
- Romero-Gonzalez Juan P.
- Ronchini Ana Lucia Vitti
- Rooney Glenda
- Rosado Ines
- Rosalia Rodney
- Rosati Moris
- Rose Bernd Oliver
- Rose Louise
- Rostello Oscar Fernández
- Rothenfusser Monika
- Rubulotta Francesca
- Rubulotta Giorgia
- Rygvadottir Brynja
- Saager Leif
- Sabbag Ignacio
- Saha Rajnish
- Sakki Jenni-Katarina
- Sakuramoto Hideaki
- Salazar Janel
- Salberg Armorel
- Salman Fatema
- Salo Swagotika
- Salvà-Costa Vicent
- Samat Noryani Mohd
- Sanchez Losune Cano
- Sanchez Maria Angeles Hurtado
- Sanchez-Hurtado Luis Alejandro
- Sandberg Ulla
- Sandesc Dorel
- Sankar-Maharaj Sasha
- Sankey Babangida John
- Santiago Eleanor
- Santos Jacinta
- Santos Rayanne
- Sanz Luz Coronado
- Sanz Miquel
- Sarkar Nikki
- Saul Pablo
- Sawawiboon Chaiwut
- Schaller Stefan
- Schallom Marilyn
- Schefold Joerg C.
- Schmidt Raysa Cristina
- Schmollgruber Shelley
- Schmukler Armando
- Schmutz René
- Schulze Tobias
- Schüppel Sebastian
- Scire Giovanni
- Scutariu Monica Adriana
- Sellami Walid
- Sepulveda Maria Idalia
- Sergeev Dmitry
- Serin Sibel Ocak
- Seromenho Vanda
- Serpa Leticia
- Sertznig Claude
- Setten Mariano
- Shah Bhagyesh
- Shao Hongyan
- Shaw David
- Shawish Sabah Abu
- Shayamano Rosina
- Sheehan Christine
- Shen Yanling
- Sherwin James
- Shi Guanxiu
- Shi Zeya
- Shime Nobuaki
- Shimizu Masako
- Short Jack
- Shosholcheva Mirjana
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- Sierra Rafael
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- Sim Yun Su
- Simi Marcelo
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- Singh Keevan
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- Slobodianiuk Gari
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- Smajic Jasmina
- Smiley Kathleen Ann
- Smith Catherine
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- Smith Julie
- Smith Neil
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- Somerville Justine
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- Song Bing
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- Song Min
- Song Rima
- Sosa Miguel Ángel
- Sosnowski Kellie
- Sostaric Maja
- Soula Enas
- Soulisse Léa
- Soundoulounaki Stella
- Souppart Virginie
- Sourla Evdokia
- Sousa Bruno
- Spadaro Savino
- Spina Rosario
- Spyropoulou Anastasia
- Spångfors Martin
- Stafylaraki Maria
- Staikos Ioannis
- Stalika Kristina Mariana Matei
- Stanojević Maja
- Starchenko Irina
- Stefanovic Branislava
- Steffenak Elin
- Stehr Sebastian
- Stenset Ane
- Stiban Sonia
- Stivanello Lucia
- Stojanovic Milena
- Stones Elizabeth
- Straede Esben
- Stübner Andeas
- Subedi Nisha Bhandari
- Suen Gabriel
- Sulaiman Siti Rohayah
- Sun Chengxia
- Sun Wei
- Sun Yue
- Susanti Ade
- Sustic Alan
- Swinnen Walter
- Syed Muhommed Ridwaan
- Sykehus Drammen
- Szakmany Tamas
- Sánchez-Hurtado Luis
- Tababa Osama Wanees Emhemid
- Tabah Alexis
- Tabib Majd
- Taghavi Noushin
- Taibi Maria Rosa
- Taito Shunsuke
- Tak Poon Shing
- Takahashi Kenji
- Talik Imen
- Tallot Mandy
- Tamayo Luis Mario
- Tamme Kadri
- Tan Lei
- Tao Jing
- Tapia Fernando
- Tavares Ana
- Taşdemir Banu
- Teig Magnus
- Tejeda-Huezo Brigitte
- Telleria Vanesa Mercado
- Templeton Mae
- Terry Dorothy
- Tervo-Heikkinen Tarja
- Thankamma Bindu
- Theisen Christian
- Thix Cyril
- Tholioti Thomai
- Thoma Giannoula
- Thomas Beverley
- Thompson Amy
- Thompson Lorraine
- Thomsen Tina Damgaar
- Thorpe Elaine
- Tian Eryun
- Tian Xiao Fang
- Tian Yani
- Tian Zhixia
- Timsit Jean-Francois
- Tingsvik Catarina
- Tirado Celia
- Toellefsen Annette
- Tokareva Ekaterina
- Tokur Murat Emre
- Tole Eunice
- Tomescu Dana
- Tong Jenny May Geok
- Tonkovic Dinko
- Toppin Patrick
- Torlinski Tomasz
- Traina Lidia
- Tranello Francesca Paola
- Tribulev Maksim
- Tridente Ascanio
- Triki Ahmed Ramadan
- Tripathy Swagata
- Trongtrakul Konlawij
- Trongtratul Konlawij
- Trposak Angela
- Trudvang Siw
- Trueman-Dawkins Treiza
- Tsarev Alexander
- Tsikriki Syragoula
- Tsikritsaki Kyriaki
- Tsujimoto Mayumi
- Tubacka Marta
- Tuinstra Binny
- Tuo Lili
- Turan Can
- Turan Sema
- Turc Jean
- Turner Sarah Jane
- Turčan Anton
- Tutillo Diego Rolando Morocho
- Twagirumugabe Theogene
- Twiggs Hilary
- Uba Stella
- Uccelli Francesco
- Udiljak Nikolina
- Ugwu Innocent
- Umek Nejc
- Undar Hasan Nabi
- Vakalos Aristeidis
- Valerio Idália
- Valgolio Emanuel
- Valta Maija
- Valta Maija Anniina
- van Axel Alisha
- Van Cotthem Ilse
- Van de Velde Stijn
- Van Den Berg Lettie
- Van Den Brink Mark
- Van Den Elst Arlette
- van der Kuil Mark
- Van Gulik Laura
- Van Regenmortel Niels
- Van Vliet Peter
- Vanroest Margijske
- Varela Maria
- Vaschetto Rosanna
- Vasquez Alexandra
- Vaughan-Jones Nicola
- Velickovic Jelena
- Veličković Dejan
- Ventour Dale
- Vermeijden Jan Wytze
- Vieira João
- Villa Robert
- Villafuerte Missael Vladimir Espinoza
- Villanueva Ximena
- Villegas Paula
- Viveiros Abel
- Vizcaychipi Marcela
- Vlaovic Janko
- Vochin Ana
- Volta Carlo Alberto
- von der Osten Ingrid
- Von Der Osten Ingrid
- von Lewinski Dirk
- Vosylius Saulius
- Vuković Anita
- Vullum Sylvi
- Vymazal Tamas
- Vymazal Tomas
- Wahab Sherliza
- Wahlbom Ewa
- Waibel Hansjoerg
- Wallin Ewa
- Walsh Amy
- Wan Jianhong
- Wan Yan
- Wang Damei
- Wang Fanglan
- Wang GuoXian
- Wang Hai Yun
- Wang Haiyan
- Wang Jing
- Wang Kefang
- Wang LingLing
- Wang RuiXia
- Wang Shuhui
- Wang Shuo
- Wang Wei
- Wang Wenmei
- Wang Xiaomin
- Wang Yan
- Wang Ying
- Wang Yingli
- Wang Yuping
- Wang Yuxia
- Watts Stacey
- Waweru-Siika Wangari
- Wei Dongfang
- Wei Wei
- Wei Xiyan
- Wei Ying
- Welters Ingeborg D.
- White Joanne
- White Nigel
- Whiteley Simon
- Whitticase Richard
- Wiborg Elisabeth
- Wijnands Patricia
- Wilby Liz
- Williams Anne
- Williams Ged
- Williams Helen
- Williams Karen
- Williams Lynne
- Wilting Rob
- Wise Robert
- Woods Justin
- Wright Kerry
- Wu Juan
- Wu ShiFen
- Wu Xiaojun
- Wu Xiaoying
- Wu Yang
- Wu Yun
- Wu Zijing
- Xhindi Nordian
- Xia Chun Jie
- Xia Xinhua
- Xiao Lina
- Xiao Min
- Xiao Yan
- Xiaoyan Yang
- Xie Yan
- Xing Cynthia
- Xiong Yunfeng
- Xixi Li
- Xu Lina
- Xu Xiao
- Xu Xuelian
- Xu Yan
- Xue Xiujuan
- Yaghi Aktham
- Yakubu Yakubu H.
- Yamamoto Ryohey
- Yan Howe
- Yan Xiaoli
- Yan Yan
- Yang Fan
- Yang Fengling
- Yang Huai
- Yang Jing
- Yang Lei
- Yang Qiao
- Yang Shunzhu
- Yang Yanping
- Yang YongXia
- Yao Xiuying
- Yao Yanlan
- Yao Zhiru
- Ye Man
- Ye Mei
- Yeni Nomhle Princess
- Yeon-Joo Lee
- Yildiz İsmail
- Yilmaz Hakan
- Yin Hai
- Yin Li
- Young Charlotte
- Young-Jae Cho
- Yu Jing
- Yu Min
- Yu Tingting
- Yu Zhu Jun
- Yuan Cui
- Yuan Weilian
- Yuan Yuxia
- Yuchen Wu
- Yuemen Ly
- Yumei Chen
- Zahra Hajer Ben
- Zainudin Asmah
- Zakalik Graciela
- Zaki Ahmed
- Zalba-Etayo Begoña
- Zamora Purificacion Sanchez
- Zamorano Matias Jesús Flamm
- Zan Tao
- Zand Farid
- Zarei Fatemeh
- Zeng Jing Mei
- Zeng Qi
- Zepoy Sofia
- Zerman Avşar
- Zermeno Jorge Macias
- Zgrzheblovska Lesia
- Zhang Aizhi
- Zhang Baoke
- Zhang Feifei
- Zhang Guiping
- Zhang Hong
- Zhang Hongsu
- Zhang Hui
- Zhang Jing
- Zhang Jundi
- Zhang Libing
- Zhang Ling
- Zhang Na
- Zhang Wei
- Zhang Yali
- Zhang Ying
- Zhang Zhenxia
- Zhao Hui Min
- Zhao Lijuan
- Zhao Lina
- Zhao Qian
- Zhao Qingli
- Zhao Rong Hua
- Zhao Ronghua
- Zhao Wenwen
- Zhao Yingjuan
- Zhedaeva Marina
- Zheng Hong
- Zheng Jing
- Zheng Xianhong
- Zhigang Zhang
- Zhijuan Wang
- Zhiping Sun
- Zhivotneva Trina
- Zhou Yuming
- Zhu Guoyan
- Zhu JiFen
- Zhu Jin Yu
- Zivanovic-Posilovic Gordana
- Zorko Nika
- Zubareva Nadezhda
- Zuev Evgeniy
- Zueva Oksana
- Zulkifli Zulkifli
- Ágoston Zsuzsann
- Åkerman Eva
- Çelik Jale Bengi
- Ñamendys-Silva Silvio A.
- Özcan Beysim
- Özserezli Boğaç
- Ünlü Nurdan
- Čuljak Hemena
- Şentürk Evren
- Šuput Aleksandar
- Publication venue
- Intensive Care Medicine
- Publication date
- 09/04/2021
- Field of study
The original version of this article unfortunately contained a mistake
Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
- Author
- Aaron Joffe
- Aaron Mark Hernandez
- Aaron Mark Hernandez
- Abby Lewis
- Abdelhamid Hachimi
- Abdualhamid I Alshrif
- Abel Viveiros
- Abhijit Duggal
- Abidin Oner Balbay
- Achilleas Chovas
- Ade Susanti
- Adi Hadzibegovic
- Adonis Dungca
- Adrian Belii
- Adrian Belii
- Adriana Onelli
- Afolabi Owojuyigbe
- Agnieszka Kubisz-Pudelko
- Agnès Blanc
- Ahmed Ali Aboufray
- Ahmed Elhadi
- Ahmed Ramadan Triki
- Ahmed Subhy Alsheikhly
- Ahmed Zaki
- Ahmet Eroglu
- Aidan O'Shea
- Aikaterini Dimoula
- Aikaterini Efthimiou
- Aikaterini Flevari
- Ailesh Corcoran
- AiPing Bi
- Aiua Ren
- Aizhi Zhang
- Ajitha Rajendran
- Akemi Hirao
- Akira Ohuchi
- Aktham Yaghi
- Ala Khaled
- Alan Sustic
- Alan Sustic
- Alba Riera
- Alban Greca
- Alberto de Jesús Ortiz
- Alberto Peratoner
- Alejandra Aucapina
- Alejandra Azahara Marguello Fernandez
- Alejandro Ibarra
- Aleksandar Šuput
- Aleksandra Gutysz-Wojnicka
- Alessandra Negro
- Alessandro Di Risio
- Alessandro Galazzi
- Alexander Dullenkopf
- Alexander Kiselev
- Alexander Tsarev
- Alexandra Pivkina
- Alexandra Vasquez
- Alexis Tabah
- Ali Kağnıcı
- Alida Moise
- Aline Ramalho
- Alinoy Lavy
- Alisha van Axel
- Alma Cani
- Alvaro Ortega Guerrero
- Amalia Corso
- Amber Markham
- Amelia Ferreira
- Amer Assiri
- Amilcar Garcia
- Amilcar Garcia
- Amit Gupta
- Amit Gupta
- Amy Collins
- Amy Thompson
- Amy Walsh
- Amylkar Garay Reyes
- Amylkar José Garay Reyes
- Ana Alabart Llinas
- Ana Alícia Velarde Pineda
- Ana Bantar
- Ana Belén Curto Polo
- Ana Belén Sánchez de la Ventana
- Ana Diaz
- Ana Diaz
- Ana Isabel Clement
- Ana Laura Gonzalez
- Ana Lucia Vitti Ronchini
- Ana Margarida Feranandes
- Ana María De Pablo
- Ana Pascual-Bielsa
- Ana Tavares
- Ana Vochin
- Ana Wensell Fernández
- Anastasia Spyropoulou
- Anastasio Espejo Cano
- Andeas Stübner
- Andrea Bruni
- Andrea Cortegiani
- Andrea Cortegiani
- Andrea Cortegiani
- Andrea Giampaoletti
- Andrea Martonova
- Andrea Martonova
- Andrea McDonnell
- Andrea McLucas
- Andrej Markota
- Andrijan Kartalov
- Andréa Maria Laizner
- Andréa Maria Laizner
- Andréa Maria Laizner
- Ane Stenset
- Angela Trposak
- Angelica Olivetto de Almeida
- Anisette Hoegenhaven
- Anita Alias
- Anita Jans
- Anita Vuković
- Anita-Chrysolyte Kusi-Appiah
- Anja Diers
- Anja Hansen
- Ann-Sofie Malvemyr
- Anna Alexandrou
- Anna Diaz
- Anna Efthymiou
- Anna Kyriakoudi
- Anna Leonova
- Anna Vita Bruno
- Anne Fishman
- Anne Langvad
- Anne Marie Kodal
- Anne Sofie Bomholt Pedersen
- Anne Williams
- Anne-Sophie Debue
- Annette Carey
- Annette Toellefsen
- Anthony Adenekan
- Anthony Radavidson
- Antigoni Karathanou
- Anton Turčan
- Antonella Cotoia
- Antonella Mo
- Antoni Margarit Ribas
- Antonia Liarmakopoulou
- Antonija Petosic
- Antonino Rizzo
- Antonio Abdala
- Antonio Barone
- Antonio Landaverde
- Antonio Manzo
- Antonio Margarit Ribas
- Antony Eneas
- Apostolos Bakas
- Arena Raimondo
- Arif Moghal
- Aristeidis Vakalos
- Arlette Van Den Elst
- Armanda Bozena
- Armando Schmukler
- Armorel Salberg
- Artemis Patsalos
- Arturo Briva
- Arvind Baronia
- Asbjorn Blondal
- Ascanio Tridente
- Ashish K Khanna
- Ashish K Khanna
- Ashish Khanna
- Ashley Szabo Eltorai
- Ashok Sundai Raj
- Ashwaq Ali
- Asmah Zainudin
- Asu Ozgultekin
- Ata Mahmoodpoor
- Athena Lavrentieva
- Attilio Quaini
- Audrey Fioretti
- Audrey Massard
- Auke Reidinga
- Auli Palmu
- Avşar Zerman
- Aya Alabuzidi
- Ayako Noguchi
- Ayça Gümüş
- Azmin Huda Abdul Rahim
- Babangida John Sankey
- Badiola Hilario
- Banu Taşdemir
- Baoke Zhang
- Barbara Garcia
- Barbro Meland
- Bart Ramaker
- Basri Mat Nor
- Battsetseg Baasanjav
- Başar Erdivanli
- Başar Erdivanli
- Beatrice Pastore
- Begoña Zalba-Etayo
- Belen Burgos Conde
- Belinda Guadi-Gosh
- Ben Attwood
- Benjamin Bongiorno
- Benjamin Gerretsen
- Benoît Chinardet
- Berenice Navarro
- Bernardo Panka
- Bernardo Panka
- Bernd Oliver Rose
- Bert Loef
- Betty Star Kampayana
- Beverley Thomas
- Beysim Özcan
- Beysim Özcan
- Bhagyesh Shah
- Biljana Kuzmanovska
- Bindu Thankamma
- Bing Song
- Binny Tuinstra
- Birgitte Fosser Johansen
- Birthe Husted
- Biyan Li
- Bjoern Monsen
- Bjorn Bratsberg
- Bodin Khwannimit
- Bogdan Raitsiou
- Bojan Jovanovic
- Bonnie Bowes
- Boğaç Özserezli
- Bram Kilapong
- Bram Kilapong
- Branislava Stefanovic
- Brian Marsh
- Brigitte Tejeda-Huezo
- Brita Fosser Olsen
- Britt Galaaen
- Britt Sjobo
- Britta Jepsen
- Bronagh Blackwood
- Bruno Miguel Bispo
- Bruno Sousa
- Bruno Sousa
- Brynja Rygvadottir
- Burhan Hadri
- Burhan Hadri
- Byung Ju Kang
- Caihong Hui
- Caiju Song
- Caitriona Cody
- Can Turan
- Carita Löfqvist
- Carlo Alberto Volta
- Carlos Alejandro Bascary
- Carlos Castro Delgado
- Carmel Chapman
- Carmel Georgiev
- Carmen Partera Luque
- Carmen Velasco Guillén
- Carole Boulanger
- Carole Boulanger
- Carole Brett
- Carolina Garzón-Tovar
- Carolina Palaez
- Caroline Lagerhäll
- Caroline O'Donnell
- Caroline Paillet
- Carrie Sona
- Casiano Barrera Groba
- Catalin Traian Guran
- Catarina Nunes
- Catarina Tingsvik
- Catherine Motherway
- Catherine O'Brien
- Catherine Smith
- Cathy Becker
- Catia Quagliotto
- Cecilia Inés Loudet
- Cecilia Loudet
- Celia Tirado
- Ceri Lynch
- Cesar Aponte
- Cesar Rodriguez Nuñez
- Chaiwut Sawawiboon
- Chaoqun Ma
- Charalampos Martinos
- Charalice Ramiro
- Charikleia Nikolaou
- Charlotte Carter
- Charlotte Young
- Charlotte Young
- Chen Yumei
- Cheng
- Chenghau Mu
- Chengxia Sun
- Cheryl Bealer
- Cheryl Davidson
- Chiara Gatti
- Chiara Megna
- Chiara Megna
- Cho Young-Jae
- Chris Gerome Ellazar
- Chris Smith
- Chrisi Diakaki
- Christian Ferretti
- Christian Frey
- Christian Theisen
- Christiana Chime
- Christine Fiedler
- Christine Sheehan
- Christophe Borin
- Christophe Giacardi
- Christopher Barnes
- Christopher Barnes
- Christopher Palfreeman
- Christopher Potestio
- Christos Christofis
- Christos Dragoumanis
- Chrysanthos Markoulias
- Chrysostomos Katsenos
- Chun Jie Xia
- Chunxia Li
- Cindy Barefield
- Cindy Pillard
- Cintia Valencia Hurtado
- Cinzia Borgognoni
- Claire Derbyshire
- Claire Randell
- Claire Reynolds
- Clara Hurtado
- Clara Santa Rita
- Clare Fielding
- Clare Howcroft
- Claude Sertznig
- Claudia Lizbeth Lopez Nava
- Claudia Martins
- Congcong Liu
- Constantina Constantinou
- Cristal April Jane Aperocho
- Cristian Quiroga
- Cristiana Mota Pinheiro
- Cristina Paños Espinosa
- Cristina Petrisor
- Cui Yuan
- Cynthia Xing
- Cyril Thix
- Cyril Thix
- Cédric Bruel
- Cédric Daubin
- Dagmar Holmquist
- Daira Gonzalez
- Daisy Mehay
- Dale Ventour
- Damei Wang
- Damien O'Connell Rosemary Finn
- Dana Tomescu
- Dana Tomescu
- Danca Lančaričová
- Daniel Blanco
- Daniel Horner
- Daniel Owens
- Daniel Sancho Muriel
- Daniela Alampi
- Daniela Carmen Filipescu
- Danielle Hacking
- Danil Baskakov
- Daria Rabarova
- Dassy Levy
- David De Bels
- David Higgins
- David Perez-Torres
- David Shaw
- Davide Massimo Ghioldi
- Dea Mahanes
- Debbie Noblezada-Uy
- Deborah Jibrin
- DeHong Lei
- Deirdre Doyle
- Dejan Veličković
- Delmiro Becker
- Delphine Ngo
- Demet Tok Aydin
- Detlef Kindgen-Milles
- Devrim Akdağ
- Deyan Cao
- Diana Alvarez
- Diane Barkas
- Dianne Figaro-Barclay
- Dick Nahar
- Diego Rolando Morocho Tutillo
- Dimitra Lepida
- Dimitrios Papadopoulos
- Dinko Tonkovic
- Dirk von Lewinski
- Dmitriy Galishevskiy
- Dmitry Sergeev
- Dolly Mabel Bordon Cabral
- Dominic Carney
- Donaldo S Arteta Arteta
- Dongfang Wei
- Dongliang Lin
- Dongmei Bai
- Dongshu Ni
- Donna Cummings
- Dorel Sandesc
- Dorothee Mueller
- Dorothy Terry
- Drammen Sykehus
- Dritan Muzha
- Dritan Muzha
- Duygu Kayar Calili
- Dylan De Lange
- Dylan De Lange
- Edda Johansen
- Edwin Chapeta
- Egide Buregeya
- Egidija Bielskute
- Eileen Gilder
- Eirini Pantiora
- Eirini Papageorgiou
- Eirini-Chysovalanto Patsiou
- Ekaterina Tokareva
- Elaine Barros
- Elaine Thorpe
- Eleanor Santiago
- Elena Molinos
- Eleni Achilleos
- Eliane Mazocoli
- Elie Gharios
- Elif Erdogan
- Elif Erdogan
- Elin Kristoffersen
- Elin Mari Skorstad
- Elin Steffenak
- Elina Karjula
- Elisabet Gallart
- Elisabeth Wiborg
- Elisabetta Brizio
- Elizabeth Campbell
- Elizabeth Maidana
- Elizabeth Stones
- Ella Rokosh
- Elsa Afonso
- Elsa Afonso
- Emanuel Valgolio
- Emiliano Dean
- Emilio Maseda
- Emma Aves
- Emma Moreno Barreiro
- Emma Parkin
- Enas Soula
- Eneli Anvelt
- Enora Atchade
- Epaminontas Farmakis
- Erik Roman-Pognuz
- Erika Backlund Jansson
- Eryun Tian
- Esben Straede
- Esteban Milioto
- Estefania Orozco
- Estefanía Prol-Silva
- Estevão Lafuente
- Etienne De Montmollin
- Eugenio Garofalo
- Eugenio Martinez-Hurtado
- Eugeniya Larina
- Eulália Luis
- Eumorfia Kondili
- Eunice Tole
- Eva Joelsson-Alm
- Eva Joelsson-Alm
- Eva Åkerman
- Eva Åkerman
- Evangelia Michailidou
- Evdokia Sourla
- Evellyn Oliveira
- Evgeniy Zuev
- Evren Şentürk
- Ewa Wahlbom
- Ewa Wallin
- Fabienne Etourneau
- Fabio Capuzzi
- Fabio Guarracino
- Fan Yang
- Fanglan Wang
- Farid Zand
- Farshad Heidari
- Fatema Salman
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- Silvie Allaert
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- Silvio A Ñamendys-Silva
- Simant Jha
- Simeon Olanipekun
- Simeon Olanipekun
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- Simon Mandaroux
- Simon Whiteley
- Simona Casaioli
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- Stephanie Harris
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- Stephen J Brett
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- Theogene Twagirumugabe
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- Tina Damgaar Thomsen
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- Ting Han
- Tingting Li
- Tingting Yu
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- Vanesa Mercado Telleria
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- Vitaly Gusarov
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- Vitor Manuel Vaz Pinto
- Viveca Hamback Hellkvist
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- Volodymyr Babych
- Vongayi Ogbeide
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- Wendy Chaboyer
- Wendy Milner
- Wenjie Ju
- Wenmei Wang
- Wenmin Chen
- Wenwen Zhao
- Wenzhen Cao
- Wesal Ali Belkhair
- Willem Dieperink
- Windu Baskoro
- Won-Yeon Lee
- Wu Yuchen
- Xia Cui
- Xia Huang
- Xianhong Zheng
- Xianping Luo
- Xiao Fang Tian
- Xiao Xu
- XiaoChun Hu
- Xiaodi Liu
- Xiaofang Luo
- Xiaohan Li
- Xiaohan Li
- Xiaojun Wu
- Xiaoli Yan
- Xiaomin Wang
- Xiaoqiong Deng
- Xiaowu Bai
- Xiaoyan Chen
- Xiaoyan Chen
- Xiaoying Wu
- XiaoZhe Liu
- Ximena Villanueva
- Xingguo Li
- Xinhua Xia
- Xinhua Xia
- Xinjian Li
- Xinran Ding
- Xinxia Li
- Xinxia Li
- Xiuhua Fang
- Xiuhua Fang
- Xiujuan Xue
- XiuMei Liu
- Xiuying Yao
- Xiyan Wei
- Xu Peipei
- Xue Lin
- Xue Qin Li
- Xuejuan Liang
- XueLian Liu
- Xuelian Pang
- Xuelian Xu
- Xueping Jiao
- Yajun Ding
- Yakubu H Yakubu
- Yali Zhang
- Yalım Dikmen
- Yalım Dikmen
- Yalim Dikmen
- Yan Gao
- Yan Li
- Yan Liu
- Yan Liu
- Yan Long
- Yan Wan
- Yan Wang
- Yan Xiao
- Yan Xie
- Yan Xu
- Yan Yan
- Yanfei Long
- Yang Lei
- Yang Liu
- Yang Wu
- Yang Xiaoyan
- Yanhong Di
- Yanhua Hao
- Yani Tian
- Yanlan Yao
- Yanling Shen
- Yanman Jian
- Yanmei Gu
- Yanming Ding
- Yann Le Guen
- Yanping Yang
- Yasser Mandourah
- Yenny Cardenas
- Yenny Cardenas
- Yesim Serife Bayraktar
- Yin He
- Ying Cao
- Ying Li
- Ying Liu
- Ying Wang
- Ying Wei
- Ying Zhang
- Yingjuan Zhao
- Yingli Wang
- Yinhua Guo
- Yolanda Mendiara
- YongXia Yang
- Yoshimasa Nishime
- Yoshiro Hayashi
- Youjin Chang
- Youru Jiang
- Youssef Zied Elhechmi
- Ysica Acosta
- Yu Chao
- Yu Han
- Yu Liu
- Yu Liu
- Yue Sun
- Yue Ying Gong
- Yuming Zhou
- Yun Su Sim
- Yun Wu
- Yunchun Dong
- Yunfeng Xiong
- Yupeng Liu
- Yuping Wang
- Yuxia Huo
- Yuxia Wang
- Yuxia Yuan
- Yvan Fleury
- Yvonne Andersen
- Zainab Ateya
- Zaneta Bogoevska-Miteva
- Zeya Shi
- Zhang Zhigang
- ZhangShuangzi Li
- ZhangXia Feng
- Zhaoxia Feng
- Zhaoxing Dai
- Zhenxia Zhang
- Zhihong Chen
- Zhiru Yao
- Zhixia Jiang
- ZhiXia Jiang
- Zhixia Tian
- Zhu Jun Yu
- Zhuqing Li
- Zied Hajjej
- Zijing Wu
- Zsuzsann Ágoston
- Zu Qing Cao
- Zulkifli Zulkifli
- Ângela Lima
- Publication venue
- Intensive Care Medicine
- Publication date
- 29/08/2020
- Field of study
Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat
Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight NCD Risk Factor Collaboration (NCD-RisC)
- Author
- Abarca-Gómez Leandra
- Abdeen Ziad A
- Abdrakhmanova Shynar
- Abu-Rmeileh Niveen M
- Acosta-Cazares Benjamin
- Adams Robert J
- Aekplakorn Wichai
- Afsana Kaosar
- Afzal Shoaib
- Agdeppa Imelda A
- Aghazadeh-Attari Javad
- Aguilar-Salinas Carlos A
- Agyemang Charles
- Ahmad Mohamad Hasnan
- Ahmad Noor Ani
- Ahmadi Ali
- Ahmadi Naser
- Ahmed Soheir H
- Ahrens Wolfgang
- Aitmurzaeva Gulmira
- Ajlouni Kamel
- Al Nsour Mohannad
- Al-Hazzaa Hazzaa M
- Al-Lahou Badreya
- Al-Raddadi Rajaa
- Alarouj Monira
- AlBuhairan Fadia
- AlDhukair Shahla
- Ali Mohamed M
- Alkandari Abdullah
- Alkerwi Ala'a
- Allin Kristine
- Alvarez-Pedrerol Mar
- Aly Eman
- Amarapurkar Deepak N
- Amiri Parisa
- Amougou Norbert
- Amouyel Philippe
- Anderssen Sigmund A
- Anjana Ranjit Mohan
- Ansari-Moghaddam Alireza
- Aounallah-Skhiri Hajer
- Araújo Joana
- Ariansen Inger
- Aris Tahir
- Arku Raphael E
- Arlappa Nimmathota
- Aryal Krishna K
- Aspelund Thor
- Assah Felix K
- Assunção Maria Cecília F
- Aung May Soe
- Auvinen Juha
- Avdicová Mária
- Avi Shina
- Azevedo Ana
- Azimi-Nezhad Mohsen
- Azizi Fereidoun
- Azmin Mehrdad
- Babu Bontha V
- Baharudin Azli
- Bahijri Suhad
- Baker Jennifer L
- Balakrishna Nagalla
- Bamoshmoosh Mohamed
- Banach Maciej
- Bandosz Piotr
- Banegas José R
- Bao Tran Quoc
- Baran Joanna
- Barbagallo Carlo M
- Barceló Alberto
- Barkat Amina
- Barros Aluisio JD
- Barros Mauro Virgílio Gomes
- Basit Abdul
- Bastos Joao Luiz D
- Bata Iqbal
- Batieha Anwar M
- Batista Rosangela L
- Battakova Zhamilya
- Batyrbek Assembekov
- Baur Louise A
- Beaglehole Robert
- Bebakar Wan Mohamad Wan
- Bel-Serrat Silvia
- Belavendra Antonisamy
- Benchekor Sounnia Mediene
- Benedics Judith
- Benet Mikhail
- Bennett James E
- Bergh Ingunn Holden
- Berkinbayev Salim
- Bernabe-Ortiz Antonio
- Bernotiene Gailute
- Bettiol Heloísa
- Bezerra Jorge
- Bhagyalaxmi Aroor
- Bharadwaj Sumit
- Bhargava Santosh K
- Bhutta Zulfiqar A
- Bi Hongsheng
- Bi Yufang
- Bia Daniel
- Bikbov Mukharram M
- Bista Bihungum
- Bixby Honor
- Bjelica Dusko J
- Bjerregaard Peter
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- Bjertness Marius B
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- Bloch Katia V
- Blokstra Anneke
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- Boddy Lynne M
- Boehm Bernhard O
- Boeing Heiner
- Boggia Jose G
- Bogova Elena
- Boissonnet Carlos P
- Bojesen Stig E
- Boker Lital Keinan
- Bonaccio Marialaura
- Bongard Vanina
- Bonilla-Vargas Alice
- Bopp Matthias
- Borghs Herman
- Bovet Pascal
- Braeckevelt Lien
- Braeckman Lutgart
- Bragt Marjolijn CE
- Brajkovich Imperia
- Branca Francesco
- Braunerová Radka Taxová
- Breckenkamp Juergen
- Breda João
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- Brian Garry R
- Brinduse Lacramioara
- Brophy Sinead
- Bruno Graziella
- Bueno-de-Mesquita H Bas
- Bugge Anna
- Buoncristiano Marta
- Burazeri Genc
- Burns Con
- Cacciottolo Joseph
- Cadena Leticia Hernandez
- Cai Hui
- Cama Tilema
- Cameron Christine
- Camolas José
- Can Günay
- Capanzana Mario V
- Capková Nadežda
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- Cardol Marloes
- Cardoso Viviane C
- Carlsson Axel C
- Carmuega Esteban
- Carrillo-Larco Rodrigo M
- Carvalho Joana
- Casajús José A
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- Chetrit Angela
- Chikova-Iscener Ekaterina
- Chiolero Arnaud
- Chiou Shu-Ti
- Chirita-Emandi Adela
- Chirlaque María-Dolores
- Cho Belong
- Christensen Kaare
- Christofaro Diego G
- Chudek Jerzy
- Cifkova Renata
- Cilia Michelle
- Cinteza Eliza
- Cisneros Julio Zuñiga
- Claessens Frank
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- Czenczek-Lewandowska Ewelina
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- D'Arrigo Graziella
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- da Silva Bruna Goncalves Cordeiro
- Dacica Liliana
- Dallongeville Jean
- Damasceno Albertino
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- Danaei Goodarz
- Dankner Rachel
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- Dasgupta Parasmani
- Dastgiri Saeed
- Dauchet Luc
- Davletov Kairat
- De Backer Guy
- De Bacquer Dirk
- de Gaetano Giovanni
- De Henauw Stefaan
- de León Antonio Cabrera
- de Oliveira Paula Duarte
- de Paiva Karina Mary
- De Ridder David
- De Ridder Karin
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- De Smedt Delphine
- de Souza Wanderley Júnior Rildo
- de Wit Tobias F Rinke
- Deepa Mohan
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- del Cristo Rodriguez-Perez María
- Delisle Hélène
- Delpeuch Francis
- Demarest Stefaan
- Dennison Elaine
- Dereń Katarzyna
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- Dhimal Meghnath
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- Di Cesare Mariachiara
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- Djalalinia Shirin
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- Drygas Wojciech
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- Duda Rosemary B
- Duleva Vesselka
- Dulskiene Virginija
- Dumith Samuel C
- Dushpanova Anar
- Dzerve Vilnis
- Dziankowska-Zaborszczyk Elzbieta
- Díaz-Sánchez María Elena
- Döring Angela
- Eddie Ricky
- Eftekhar Ebrahim
- Egbagbe Eruke E
- Eggertsen Robert
- Eghtesad Sareh
- Ei K Nang Ei
- Eiben Gabriele
- Ekelund Ulf
- El Ati Jalila
- El-Khateeb Mohammad
- Eldemire-Shearer Denise
- Eliasen Marie
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- Erbel Raimund
- Erem Cihangir
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- Eslami Saeid
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- Faeh David
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- Fernandes Romulo A
- Fernández-Bergés Daniel
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- Ferrao Thomas
- Ferrari Marika
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- Ferreccio Catterina
- Ferrer Eldridge
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- Figueiró Thamara Hubler
- Fijalkowska Anna
- Filippi Sarah
- Fink Günther
- Fischer Krista
- Foo Leng Huat
- Forsner Maria
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- Francis Damian K
- Frikke-Schmidt Ruth
- Frontera Guillermo
- Fuchs Flavio D
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- Fujiati Isti I
- Fujita Yuki
- Fumihiko Matsuda
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- Gaciong Zbigniew
- Gafencu Mihai
- Galbarczyk Andrzej
- Galenkamp Henrike
- Galeone Daniela
- Galfo Myriam
- Galvano Fabio
- Gao Jingli
- Garba Jamila Abubakar
- Garcia-de-la-Hera Manoli
- García-Solano Marta
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- Gaspoz Jean-Michel
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- Gaya Anelise Reis
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- Giampaoli Simona
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- Giovannelli Jonathan
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- Goltzman David
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- González-Villalpando María-Elena
- Gonçalves Helen
- Gottrand Frederic
- Graff-Iversen Sidsel
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- Gregor Ronald D
- Grodzicki Tomasz
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- Gruden Gabriella
- Grøholt Else Karin
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- Gu Dongfeng
- Gualdi-Russo Emanuela
- Guallar-Castillón Pilar
- Gualtieri Andrea
- Gudmundsson Elias F
- Gudnason Vilmundur
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- Kersting Mathilde
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- Kheiri Bahareh
- Kheradmand Motahareh
- Khosravi Alireza
- Khouw Ilse MSL
- Kiechl Stefan
- Kiechl-Kohlendorfer Ursula
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- Rahman Mahmudur
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- Rakhmatulloev Sherali
- Rakovac Ivo
- Ramachandran Ambady
- Ramke Jacqueline
- Ramos Elisabete
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- Regecová Valéria
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- Ruidavets Jean-Bernard
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- Rusakova Iuliia A
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- Safiri Saeid
- Saidi Olfa
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- Salanave Benoit
- Salmerón Diego
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- Salvetti Massimo
- Samoutian Margarita
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- Sant'Angelo Victoria Farrugia
- Santos Diana A
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- Varela-Moreiras Gregorio
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- Velika Biruta
- Veronesi Giovanni
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- Vineis Paolo
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- Viswanathan Bharathi
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- Völzke Henry
- Wade Alisha N
- Wagner Aline
- Waldhör Thomas
- Walton Janette
- Wambiya Elvis OA
- Wang Ming-Dong
- Wang Ningli
- Wang Qian
- Wang Xiangjun
- Wang Ya Xing
- Wang Ying-Wei
- Wannamethee S Goya
- Wareham Nicholas
- Weber Adelheid
- Wedderkopp Niels
- Weerasekera Deepa
- Weghuber Daniel
- Wei Wenbin
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- Whincup Peter H
- Widhalm Kurt
- Widyahening Indah S
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- Wilks Rainford J
- Willeit Johann
- Willeit Peter
- Williams Julianne
- Wilsgaard Tom
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- Wong Andrew
- Wong Jyh Eiin
- Wong Norazizah Ibrahim
- Wong Tien Yin
- Wong-McClure Roy A
- Woo Jean
- Woodward Mark
- Wu Frederick C
- Wu Jianfeng
- Wu Li Juan
- Wu Shouling
- Xu Haiquan
- Xu Liang
- Yaacob Nor Azwany
- Yamborisut Uruwan
- Yan Weili
- Yang Ling
- Yang Xiaoguang
- Yang Yang
- Yardim Nazan
- Yaseri Mehdi
- Yasuharu Tabara
- Ye Xingwang
- Yiallouros Panayiotis K
- Yoosefi Moein
- Yoshihara Akihiro
- You Qi Sheng
- You San-Lin
- Younger-Coleman Novie O
- Yusoff Ahmad Faudzi
- Yusoff Muhammad Fadhli Mohd
- Zaccagni Luciana
- Zafiropulos Vassilis
- Zainuddin Ahmad A
- Zakavi Seyed Rasoul
- Zamani Farhad
- Zambon Sabina
- Zampelas Antonis
- Zamrazilová Hana
- Zapata Maria Elisa
- Zargar Abdul Hamid
- Zdrojewski Tomasz
- Zejglicova Kristyna
- Zeng Yi
- Zhang Luxia
- Zhang Zhen-Yu
- Zhao Dong
- Zhao Ming-Hui
- Zhao Wenhua
- Zhen Shiqi
- Zheng Wei
- Zheng Yingfeng
- Zholdin Bekbolat
- Zhou Bin
- Zhou Maigeng
- Zhu Dan
- Zins Marie
- Zitt Emanuel
- Zocalo Yanina
- Zuziak Monika
- Ängquist Lars
- Łuszczki Edyta
- Ševcíková Ludmila
- Publication venue
- eLife Sciences Publications
- Publication date
- 01/01/2021
- Field of study
From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of underweight, obesity, and severe obesity in different regions using data from 2896 population-based studies with 187 million participants. Changes in the prevalence of underweight and total obesity, and to a lesser extent severe obesity, are largely driven by shifts in the distribution of BMI, with smaller contributions from changes in the shape of the distribution. In East and Southeast Asia and sub-Saharan Africa, the underweight tail of the BMI distribution was left behind as the distribution shifted. There is a need for policies that address all forms of malnutrition by making healthy foods accessible and affordable, while restricting unhealthy foods through fiscal and regulatory restrictions
The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance
- Author
- Aanniz Tarek
- Abar Aden Elmi
- Abbad Anass
- Abdelfattah May
- Abdelhamid W.
- Abdella Saro
- Abdellah Faouzi
- Abdelmjid El Oualid
- Abdelmoula Fatma
- Abdelmoulah F.
- Abderrahmane Maaroufi
- Abderrazak Rfaki
- Abdillahi Idil Salah
- Abdissa Alemseged
- Abdo I.
- Abdoelraheem Mohamed Hassan
- Abe Haruka
- Abebe Markos
- Abechi Priscilla
- Abera Adugna
- Abi Rachid
- Abias Abe G.
- Abichu Getachew
- Abid N.
- Abid Nabil
- Abid Salma
- Abilio Nuro
- Abimbola Sharon
- Abo Shama Noura M
- Abosede O.
- Aboubaker Mohamed Houmed
- Abouelhoda Mohamed
- Abouelnaga S.
- Abualas Elamin
- Abubeker Ramalia Chabi
- Abuelenein Ehab Abdelkader
- Abuzaid Nadir
- Abworo Edward O.
- Ada Diosdado Odjama Nseng
- Addidle Michael
- Adegbola Richard
- Adegnika Akim A.
- Adegnika Ayola Akim
- Adel Abd Monaem
- Adeniji Johnson A.
- Adepetun Tomiwa
- Adesegun A.
- Adesuyi Omoare
- Adetifa Ifedayo M. O.
- Adewumi Olubusuyi M.
- Adewumi Oluwatimilehin
- Adewumi Praise
- Adeyemi Kayode T.
- Adhikari Bishwo N.
- Adil El Hamouchi
- Adjiratou Aissatou B. A.
- Adnew Bethlehem
- Adu Bright
- Adu Eric
- Adusei-Poku Mildred
- Agbenyo Seyram Bless
- Agbodzi B.
- Ageez A.M.
- Agoti Charles N.
- Aguenaou Hassan
- Agwa Sara Hassan
- Agweyu Ambrose
- Ahmed El Bara
- Ahmed Elhadi A.
- Ahmed Hatem
- Ahmed M.
- Ahmed O. S.
- Ahmed Rahma
- Ahmed Shymaa S.
- Ahmed Side Mohamed
- Ahmed Yahaya Ali
- Ahouidi Ambroise
- Ahuka-Mundeke Steve
- Ahumibe Anthony
- Ahyong Vida
- Aissam El Aliani
- Ajayi Nnennaya A.
- Ajibaye Solomon
- Ajili F.
- Ajogbasile F.V.
- Ajogbasile Fehintola V.
- Akanbi Olusola Anuoluwapo
- Akenji Blaise MBoringong
- Akhoud Youssef
- Akinola Monilade
- Akogbeto Petas
- Akoua-Koffi Chantal G.
- Akpede George O.
- Al Onifade Fattah
- Alain Etoundi Mballa
- Alaoui Afaf
- Alaoui-Amine Sanaa
- Alarif Ahlam
- Alaruusi A. M.
- Albert Mélanie
- AlEmam Adba Alfatih
- Alemayehu Dawit Hailu
- Alemu Fekadu
- Algheriani Raiva
- Ali Abraham
- Ali M.A.
- Ali Mohamed Ahmed
- Ali Mushal
- Ali Wael
- Alkarim Mona O.A.
- Allam Loubna
- Allam Mushal
- Allam Mushal
- Altamura Settimia
- Amar Narjis
- Amenga-Etego Lucas N.
- Amer K. E.
- Amer Khaled
- Amira Souissi
- Amoako Daniel G.
- Amoo Olufemi Samuel
- Amoth Patrick
- Amougou Marie
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- von Gottberg Anne
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- Wandera Dennis N.
- Wang Jing
- Wang Xiuhua
- Wani Gregory
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- Wanok Stephen
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- Waruhiu Cecilia
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- Wawina-Bokalanga Tony
- Wayengera Misaki
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- Webby Richard
- Weldemariam A.G.
- Weldemariam Atsbeha G.
- Werno Anja
- Wiley Michael R.
- Wilkinson David
- Wilkinson Eduan
- Williamson Carolyn
- Wilson Shannon
- Woelfel R.
- Wohl Shirlee
- Wolh S.
- Wolter Nicole
- Wuduri Zara
- Wulf Ben
- Wurie I.
- Wurie Isatta
- Xavier Joicymara S.
- Xiang Zuzheng
- Xie Hong
- Yadouleton Anges
- Yadouleton Yahya
- Yakout Mostfa
- Yandoko Rivalyn Nakoune
- Yang Qi
- Yao Kouadio T.
- Yassine Kasmi
- Yassine Zouheir
- Yasuda Jiro
- Yatassaye Bouna
- Yeboah C.
- Yeboah Richmond
- Yeboah-Manu Dorothy
- Yemi Bright K.
- Yiaba Cyrus
- Yiaba Warren Cyrus
- Yu Popova A.
- Yusuf Nyam Itse
- Yusuf Yacob Mohamed
- Zablon J. Matoke D.
- Zablon J.O.
- Zaher Tarek Refaat Elnagdy Raafat
- Zahra El Ansari Fatima
- Zahran Manal Hamdy
- Zekri Abdel-Rahman N.
- Zhang J.
- Zhou Pei
- Zinyowera Sekesai
- Zong Minko O.
- Zongo Arsène
- Zorgani A.
- Zouaki Amal
- Zulu P.
- Zumla Ali
- Zumla Alimuddin
- Zuze Boitumelo
- Publication venue
- 'American Association for the Advancement of Science (AAAS)'
- Publication date
- 07/10/2022
- Field of study
INTRODUCTION
Investment in Africa over the past year with regard to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing has led to a massive increase in the number of sequences, which, to date, exceeds 100,000 sequences generated to track the pandemic on the continent. These sequences have profoundly affected how public health officials in Africa have navigated the COVID-19 pandemic.
RATIONALE
We demonstrate how the first 100,000 SARS-CoV-2 sequences from Africa have helped monitor the epidemic on the continent, how genomic surveillance expanded over the course of the pandemic, and how we adapted our sequencing methods to deal with an evolving virus. Finally, we also examine how viral lineages have spread across the continent in a phylogeographic framework to gain insights into the underlying temporal and spatial transmission dynamics for several variants of concern (VOCs).
RESULTS
Our results indicate that the number of countries in Africa that can sequence the virus within their own borders is growing and that this is coupled with a shorter turnaround time from the time of sampling to sequence submission. Ongoing evolution necessitated the continual updating of primer sets, and, as a result, eight primer sets were designed in tandem with viral evolution and used to ensure effective sequencing of the virus. The pandemic unfolded through multiple waves of infection that were each driven by distinct genetic lineages, with B.1-like ancestral strains associated with the first pandemic wave of infections in 2020. Successive waves on the continent were fueled by different VOCs, with Alpha and Beta cocirculating in distinct spatial patterns during the second wave and Delta and Omicron affecting the whole continent during the third and fourth waves, respectively. Phylogeographic reconstruction points toward distinct differences in viral importation and exportation patterns associated with the Alpha, Beta, Delta, and Omicron variants and subvariants, when considering both Africa versus the rest of the world and viral dissemination within the continent. Our epidemiological and phylogenetic inferences therefore underscore the heterogeneous nature of the pandemic on the continent and highlight key insights and challenges, for instance, recognizing the limitations of low testing proportions. We also highlight the early warning capacity that genomic surveillance in Africa has had for the rest of the world with the detection of new lineages and variants, the most recent being the characterization of various Omicron subvariants.
CONCLUSION
Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve. This is important not only to help combat SARS-CoV-2 on the continent but also because it can be used as a platform to help address the many emerging and reemerging infectious disease threats in Africa. In particular, capacity building for local sequencing within countries or within the continent should be prioritized because this is generally associated with shorter turnaround times, providing the most benefit to local public health authorities tasked with pandemic response and mitigation and allowing for the fastest reaction to localized outbreaks. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century