87 research outputs found
Spatial memory decline after masticatory deprivation and aging is associated with altered laminar distribution of CA1 astrocytes
- Author
- Publication venue
- BioMed Central
- Publication date
- 01/01/2012
- Field of study
<p>Abstract</p> <p>Background</p> <p>Chewing imbalances are associated with neurodegeneration and are risk factors for senile dementia in humans and memory deficits in experimental animals. We investigated the impact of long-term reduced mastication on spatial memory in young, mature and aged female albino Swiss mice by stereological analysis of the laminar distribution of CA1 astrocytes. A soft diet (SD) was used to reduce mastication in the experimental group, whereas the control group was fed a hard diet (HD). Assays were performed in 3-, 6- and 18-month-old SD and HD mice.</p> <p>Results</p> <p>Eating a SD variably affected the number of astrocytes in the CA1 hippocampal field, and SD mice performed worse on water maze memory tests than HD mice. Three-month-old mice in both groups could remember/find a hidden platform in the water maze. However, 6-month-old SD mice, but not HD mice, exhibited significant spatial memory dysfunction. Both SD and HD 18-month-old mice showed spatial memory decline. Older SD mice had astrocyte hyperplasia in the strata pyramidale and oriens compared to 6-month-old mice. Aging induced astrocyte hypoplasia at 18 months in the lacunosum-moleculare layer of HD mice.</p> <p>Conclusions</p> <p>Taken together, these results suggest that the impaired spatial learning and memory induced by masticatory deprivation and aging may be associated with altered astrocyte laminar distribution and number in the CA1 hippocampal field. The underlying molecular mechanisms are unknown and merit further investigation.</p
Environmental influences on antibody-enhanced dengue disease outcomes
- Author
- Balsitis SJ
- Barreto DF
- Beaumier CM
- Beaumier CM
- Boonnak K
- Brown MG
- Brunno Gomes Pinho
- Carla M Damasceno Rego
- Colm Cunningham
- Cristovam W Picanço Diniz
- Cunningham C
- César Augusto Raiol Fôro
- Daniel Guerreiro Diniz
- Daughaday CC
- de Miranda AS
- de Sousa AA
- dos Santos HW
- Eliana Vieira Pinto da Silva
- Ferreira GP
- Friberg H
- Furuta T
- Gibbons RV
- Giovanni Freitas Gomes
- Guabiraba R
- Gubler DJ
- Halstead SB
- Hober D
- Ip PP
- Jessie K
- José Antonio Picanço Diniz
- Juliana Pastana Ramos
- Kangwanpong D
- Kinoshita D
- Kurane I
- Lu YS
- Marcia CK Sosthenes
- Marcio Roberto Teixeira Nunes
- Marina Cutrim Magalhães
- Mathew A
- Maysa de Vasconcelos Brito
- Maíra C Pereira Turiel
- Nguyen TH
- Pedro F Costa Vasconcelos
- Rothman AL
- Rothman AL
- Ruangjirachuporn W
- Samir M Moraes Casseb
- Saper CB
- Sergerie Y
- Shu SY
- Suaya JA
- Sâmia Demachki
- Tan GK
- Teeling JL
- Thomas SJ
- van Praag
- Victor Hugh Perry
- Vitarana T
- Wang WK
- Wang WK
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans
- Author
- Abbasi Z
- Abdul-Hamid M Akhlil
- Abel Paul D
- Abrams Paul H
- Adab Fawzi A
- Adamson Andrew
- Adeyoju A
- Adolfson Jan
- Afzal Naveed
- Ahiaku Ernest K N
- Ahmed Munir
- Al Sudani Mohammed L
- Al-Samarraie Amir S M
- Al-Samerraie [Unknown]
- Al-Singary Waleed
- Al-Sudani [Unknown]
- Alcock Christopher
- Alexander Kimberly
- Ali Zulfiqar
- Almond David J
- Alonzi Roberto
- Aly Markus
- Amin Al Olama Ali
- Anderson John
- Andrews Henry
- Andrews Steven
- Anjum Iqbal
- Anson Ken
- Anyamene Nicola A
- Apakama Ike
- Aparcia F
- Archbold J A A
- Arndt Volker
- Ash D
- Ashford Richard F U
- Auvinen Anssi
- Azzabi A
- Badenoch David
- Bahl Amit
- Bailey Karen
- Bailey M J
- Ball Andrew J
- Banerjee G
- Barber Jim
- Barber N
- Baria [Unknown]
- Barnes Douglas G
- Barros-Silva Joao
- Barwell Julian
- Bashir J
- Basu Pradip
- Bates Christopher A
- Batra Jyotsna
- Bax N A
- Baxter-Smith D
- Bdesha Amar
- Beacock Christopher J M
- Beaney Ronald P
- Beard Ralph
- Beatty John D
- Beck Rupert
- Beese Gail
- Beesley Sharon
- Bell C Richard W
- Bellringer James
- Benlloch Garcia Sara
- Benson Richard
- Beresford [Unknown]
- Bevis Christopher R A
- Bhana Rajanee
- Bhanot S
- Bhatnagar A
- Bhatt R I
- Birch Brian
- Birtle Alison
- Bishop M
- Biyani C Shekhar
- Blacklock A R E
- Blades Rosemary
- Bliss Peter
- Bloomfield David J
- Boddy S
- Bollina Prasad
- Bonnington Sue
- Booth C M
- Bose Pradeep
- Bott Michael C
- Bottomley David
- Boucher Nigel R
- Bowen J
- Bower Mark
- Bowsher W G
- Boyd P J R
- Bradshaw Lynne
- Bramble F James
- Brenner Hermann
- Brewster Simon F
- Briggs Tim
- Brock Cathryn
- Brock Sue
- Bromage Stephen
- Broms Michael
- Brough Richard
- Brown Andrew A
- Brown Paul
- Brown Paul M
- Brown Richard
- Brown Stephen
- Browning Tony J
- Bryan N
- Burgess Neil A
- Burns-Cox Nicholas
- Butterbach Katja
- Butterworth Paul C
- Cahill D
- Callaghan P S
- Calleary John
- Calleja M
- Calman Frances
- Camilleri Philip
- Campbell Alister
- Cannon Andrea
- Cannon-Albright Lisa
- Carnell Dawn M
- Carr T W
- Carter Adam C
- Carter Charles J M
- Carter Simon
- Castle Bruce M
- Catto James
- Cavalli-Bjoerkman Carin
- Chadwick David
- Chahal Rohit
- Chakraborti P
- Chappell [Unknown]
- Charig C
- Chetiyawardana Anula D
- Chilton Christopher
- Chinegwundoh F I
- Chong Irene
- Choudhury Ananya
- Chow Wai-Man
- Christmas Timothy J
- Christova Svetlana
- Churn Mark J
- Cieza-Borrella Clara
- Clarke Noel W
- Clavijo-Eisele Jorge
- Clements Judith A
- Coe M
- Coetzee Gerhard A
- Cohen N P
- Coker C
- Cole David J
- Cole O
- Cole Trevor
- Collins Angus
- Collins Gerald
- Collinson Matthew
- Conn I
- Connell C
- Conti David V
- Cook Audrey
- Cook Margaret
- Cooke Peter
- Cooksey Graeme
- Coombs L
- Cooper Debbie
- Copland Robert F
- Cornaby Andrew J
- Cornford P A
- Corolis [Unknown]
- Corr John
- Costello C B
- Coull Mrs N
- Cowan Richard
- Cox Angela
- Cox Robert
- Coyle C
- Crew Jeremy
- Crisp John C
- Cross W
- Cruger Dorthe
- Crundwell Malcolm
- Cummings [Unknown]
- Cybulski Cezary
- Dadaev Tokhir
- Dahar Nazeer
- Daniel Francis N
- Darrad J
- Daruwala Pallon
- Das Gautam
- Datta Shibendra
- Davidson S
- Davies Joseph
- Davis Michael
- Davison Owen W
- Dawkins Guy
- Dawson Chris
- De Bolla Alan R
- Dearnaley David
- Desai Ken M
- Deutsch George P
- Dick John
- Dickinson Andrew J
- Dickson Jeanette
- Dikov Tihomir
- Dinneen Michael
- Dixit Sanjay
- Dobbs H Jane
- Doble A
- Doble Andrew
- Dodds David
- Doherty Alan
- Donaldson P
- Donovan Jenny L
- Dooldeniya M
- Douglas S Fiona
- Down Liz
- Drake [Unknown]
- Duchesne Gill M
- Duffy Peter
- Dunn Michael
- Dunsmuir W D
- Durkan Garrett
- Durrani Sajid K
- Easton Douglas
- Eaton Alan C
- Eccles Diane
- Eckert Allison
- Eddy B
- Eden C D
- Edwards J
- Eeles Rosalind A
- El-Modir A
- Elkabir Jeremy
- Elliott Emma
- Elliott P Tony
- Ellis B W
- Ellis R
- Elves Andrew W S
- Elwell Christine
- Emberton Mark
- Emmerson Louise
- England Roland C D
- Errington R D
- Evans D Gareth
- Falconer Alison
- Fawcett Derek
- Featherston C
- Featherstone Carolyn J
- Feggetter Jeremy
- Ferguson C
- Fermont D
- Ferro Michael
- Fisher Cyril
- Fitzgerald Liesel
- Fitzgerlad Liesel M
- Fletcher Matthew
- Folkes A
- Ford Trevor F
- Foster Paul W
- Franks Kevin N
- Freedman Mathew
- Frim Olivera
- Gale Joanna
- Gallegos Christopher
- Gelister James S
- George Anne
- Ghana [Unknown]
- Gibbs Stephanie
- Gilbert Hugh
- Giles Graham G
- Gillatt David
- Glaholm John
- Glass Jonathan M
- Glenister James
- Goode Thomas D
- Gordon E M
- Govindasami Koveela
- Gower Richard L
- Graham John
- Green Damian
- Greenland Jonathan
- Grieve Robert
- Griffiths Thomas R L
- Gronberg Henrik
- Gujral Sandy
- Gupta Nishi
- Gurun Riza Murat
- Gustafsson Sven
- Guy Michelle
- Guy Peter J
- Haiman Christopher A
- Haldar Neil
- Halder N
- Haley James
- Hamdy F C
- Hamdy Freddie
- Hamilton C
- Hammonds John
- Hampson S J
- Hanbury Damien C
- Hardman P D John
- Harland Stephen J
- Harney John M
- Harper Peter
- Harris D
- Harris Sarah
- Harrison G S M
- Harriss D R
- Harvey-Hills N
- Hawkyard Simon
- Hazel Steve
- Hazelett Dennis J
- Heath Catherine M
- Heathcote Peter
- Hehir Michael
- Hellawell Giles O
- Henderson Brian E
- Hendry David
- Henley Mike
- Henrique Rui
- Henry Ann
- Herbert Pippa
- Herkommer Kathleen
- Hetherington John
- Hickish Tamas
- Hicks James A
- Hilman Serena
- Hindley Richard
- Hindmarsh John R
- Hines John
- Hingorani M
- Ho Edwin T S
- Hodgson Shirley
- Hoffman U
- Holden David
- Holding Peter
- Hollingdale A
- Hollins Graham W
- Holmes Simon A V
- Holt Sarah
- Hopper John L
- Horan Gail
- Horwich Alan
- Hoskin Peter
- Howell Graham P
- Howson Joanne
- Hrouda D
- Huddart Robert
- Hudson Liz
- Hughes Michael
- Hughes Owen
- Hughes Rob
- Humber Caroline
- Iacovou John W
- Ibrahim A
- Inglis John A
- Irving Stuart
- Irwin C
- Iversen Peter
- Izatt Louise
- Izegbu Victor
- Jameel Basharat
- James Michael J
- James N
- James R Lester
- Javle Pradip
- Jenkins P
- Jhavar Sameer
- Johansson Jan-Erik
- Jones Chris R
- Jones David A
- Jones Gareth
- Jones Mandy
- Joseph J
- Joss Shelagh
- Jugurnauth-Little Sara
- Kachakova Darina
- Kaisary Amir
- Kaliski Alexandre L
- Kaneva Radka
- Kapur G
- Karim O
- Karlsson Ami
- Karp Stephen J
- Kedda Mary-Anne
- Keeley F X
- Kelkar Anand R
- Kelleher J P
- Kelly John
- Kenwrick Sue
- Kerr Kris
- Key Tim J
- Khan F
- Khaw Kay-Tee
- Khoo Vincent
- Kibel Adam S
- Kierzek Andrzej
- Kimber Rachel M
- Kinder R
- Kirby Roger S
- Kirk David
- Kirkbride Peter
- Kirollos Magdi M
- Klarskov Peter
- Kluzniak Wojciech
- Kockelbergh Roger
- Koenig Philip C W C
- Kooiman Gordon G
- Koreich O
- Kote-Jarai Zsofia
- Koupparis Anthony
- Kourah Mohamed
- Kraus Sigurd
- Kujala Paula
- Kujawa Magda L
- Kulkarni Ravi
- Kumar M
- Kumar Rajeev
- Kunkler Ian H
- Kynaston H
- Kynaston Howard
- Lachlan Katherine L
- Laing Robert
- Lalloo Fiona
- Lancashire M
- Lane Athene
- Langley Stephen E M
- Laniado Marc
- Larner T R
- Lau Maurice W
- Lawrence W T
- Lawson Anne
- Le Roux Pieter J
- Leader Mary
- Lee A
- Lee J O
- Lee L
- Lemburger R John
- Lennon Teresa
- Leone Priscilla
- Leongamornlert Daniel
- Lester Jason
- Leung Hing
- Lewis D Christopher
- Lewis J
- Li Qiuyan
- Lim Hui-Yi
- Lin Hui-Yi
- Liston Thomas
- Livni Naomi
- Livsey Jacqueline
- Lloyd S
- Locke Imogen
- Lodge Richard
- Logue John
- Longmuir Mark
- Lophatananon Artitaya
- Lophatonanon Artitaya
- Lubinski Jan
- Lucas Malcolm G
- Luedeke Manuel
- Luscombe C J
- Lydon Anna
- Lynch Michael
- Lynn Naing N K
- Lyons Norma
- MacDermott James P A
- Macdonagh Ruaraidh P
- Macdonald [Unknown]
- Madaan Sanjeev
- Madhava Kudingila R
- Maeaettaenen Liisa
- Maguire Joseph
- Maher E R
- Mahmood Rana
- Maia Sofia
- Maier Christiane
- Mair Graeme H M
- Malone Greg
- Malone Peter R
- Mangar Stephen A
- Mantle Mark
- Mark I
- Marsden Gemma
- Mason M D
- Mason Malcolm
- Mason Robert
- Matanhelia [Unknown]
- Matenhelia Shyam
- Matthews Philip N
- McAleese J
- McBride Donna
- Mcdonnell Shannon K
- McDonnell Shannon K
- McFarlane Jonathan
- McGrath [Unknown]
- McIlhenny Craig
- McInerney Paul
- McIntosh Gregor
- McKinna F
- McLaren Duncan
- McLarty Esther
- McMenemin Rhona
- McNeill Alan
- McNicholas T A
- Meddings Robert N
- Mee A David
- Melcher Lucinda
- Memon [Unknown]
- Menzes Pravin
- Michael Agnieszka
- Miller Marek
- Mills Robert
- Mitchell S
- Mitev Vanio
- Mithal Natasha
- Mitkova Atanaska
- Mitra Anita
- Mobb Gillian E
- Moffat Leslie E F
- Mokete [Unknown]
- Money-Kyrle Julian
- Montgomery Bruce
- Moody Hilary
- Moody Martin P
- Morgan Angela
- Morley Roland
- Morris Sean B
- Morrison Patrick
- Mort Diana
- Mostafid Amir H
- Motiwala Hanif
- Mufti Gulzar
- Muir Gordon
- Muir Kenneth
- Mumtaz Faiz
- Murphy Michael
- Murray Alexandra
- Murray Keith W
- Murrell Shirley
- Murtola Teemu
- Muthukumar D
- Naerger Harry
- Namasivayam Siva
- Nargund Vinod
- Nawrocki [Unknown]
- Neal David E
- Neilson Donald
- Nethersell A
- Newby Jacqueline C
- Newman Hugh
- Newton R
- Nielsen Sune F
- Nordestgaard Børge G
- O'Boyle P J
- O'Brien J
- O'Brien Tim S
- O'Donnell H
- O'Donoghue E
- O'Donoghue Neil
- O'Reilly P
- O'Rourke J S
- O'Sullivan Joe
- O'Sullivan Patricia
- Oakley Neil
- Ogden Chris
- Ohja Hemant
- Oliver Tim
- Omara Tracy
- Ong Eng K
- Osborn David
- Ostler Peter
- Owen J
- Palfrey Edward
- Panades Miguel
- Panakis Niki
- Pancharatnam M
- Pandha Hardev
- Pantelides Michalakis L
- Panwar U
- Parikh Omi
- Park Hyun
- Park Jong Y
- Parker Chris
- Parker Christopher H
- Parys Bohdan T
- Pascoe Sarah
- Pashayan Nora
- Patel Anup
- Paterson Joan
- Pathack S
- Pati Jhumur
- Patterson Helen
- Pattu [Unknown]
- Paul A
- Paul Alan
- Paulo Paula
- Payne Heather
- Peake David
- Pedersen John
- Pedley I
- Pengelly A
- Peracha Amjad M
- Perry Matthew
- Persad Raj
- Peters John
- Pharoah Paul
- Philp N H
- Philp T
- Pickering Lisa M
- Pigott Katharine
- Pinto Pedro
- Plail R
- Plowman P Nicholas
- Pocock Richard D
- Pope A J
- Popert Rick
- Popov Elenko
- Porter Tim
- Potter John M
- Pow-Sang Julio
- Powell Christopher
- Powell Philip
- Powles Thomas B
- Prasad Krishna
- Prasad Seshadri Sri
- Prejbisz J W
- Prescott Stephen
- Protheroe Andrew
- Qureshi Khaver N
- Raby Nigel
- Radlein Selina
- Ragavan Narasimhan
- Raju Palaniappa G S
- Ramachandra Prakash B
- Raman R
- Rane Abhay
- Rankin Julia
- Rao Y
- Ratan Hari L
- Ravi Ramachandran
- Ravishankar K
- Read [Unknown]
- Reddy Paul J
- Rimington Peter R
- Rinckleb Antje
- Rincon Maria
- Riska Shaun
- Ritchie Peter A
- Roberts J Trevor
- Robertson Andrew
- Robinson Angus
- Robinson Anne C
- Robinson Lee Q
- Rochester Mark A
- Roder Andreas
- Rogers P B
- Rosario Derek
- Rosenbaum Tomas P
- Rothwell Neil
- Rowbotham Carl
- Rowe [Unknown]
- Rowley Kathryn
- Ruddy Deborah
- Rundle John
- Russell John M
- Ryan P G
- Sabharwal A
- Saggar Anand K
- Samanci Ali
- Sangar Vijay K
- Santos Joana
- Saunders Edward J
- Saunders Pamela
- Sawyer Emma J
- Saxby M F
- Schaid Daniel J
- Schleutker Johanna
- Schumacher Fredrick
- Schwaibold Hartwig
- Scoble John E
- Scrase Christopher
- Selim [Unknown]
- Sellers Thomas
- Sells Henry
- Sethia Krishna K
- Severi Gianluca
- Shackley David C
- Shaffer [Unknown]
- Shah Nihil
- Shakespeare D
- Shanley Sue
- Sharma Neerah K
- Sheehan Denise J
- Sherwin Elizabeth
- Shum Poh Lin
- Side Lucy
- Sidek Norma
- Signorello Lisa B
- Sikora Karol
- Simcock R
- Sinclair Andrew M
- Singh Pravin
- Siva M
- Slavov Chavdar
- Smith James
- Smith Michael F
- Sokal Michael
- Sole Graham M
- Southey Melissa C
- Speakman Mark J
- Spiers Alexander
- Spurdle Amanda
- Sreenivasan Thiagarajan
- Srihari Narayanan N
- Srinivasan [Unknown]
- Sriram Rajagopalan
- Staffurth John N
- Stanford Janet L
- Stattin Paer
- Stegmaier Christa
- Stephens Sarah
- Stewart D
- Stockdale Andrew
- Stott Mark A
- Stower M J
- Strachan John R
- Stuart Nicholas S A
- Sugden Elaine
- Summerton Duncan
- Sundar Santhanam
- Sundaram S K
- Suresh Gokarakonda
- Susnerwala Shabbir
- Swami Kuchibhotla S
- Symons Stephanie J
- Syndikus Isabel
- Taari Kimmo
- Tahir Saad
- Tammela Teuvo L
- Tammela Teuvo L J
- Tanquay J
- Taylor J W
- Taylor John W
- Teixeira Manuel R
- Terry T
- Thibodeau Stephen N
- Thomas Robert J
- Thomas Stephen A
- Thompson Alan
- Thompson Pauline
- Thomson Alastair H
- Thurston A
- Tidball Sarah
- Tillmans Lori
- Tilsley Owen
- Tindall Stuart F
- Tipples K
- Tong [Unknown]
- Toussi Hamid
- Toy Elizabeth W
- Travis Ruth C
- Trembath Richard C
- Tulloch David N
- Turner Kevin J
- Turner Megan
- Tweedle James
- Tymrakiewicz Malgorzata
- Tyrell C J
- Umez-Eronini N
- Urwin Graeme H
- Vale Justin A
- Van As [Unknown]
- Van As Nicholas
- Vasanthan Subramaniam
- Vesey Sean
- Vilarino-Varela Maria
- Violet John
- Virdi Jaspal
- Viñuela Ana
- Vlahova Aleksandrina
- Vogel Walther
- Wade Robert
- Wahlfors Tiina
- Waite Katherine
- Walker E M
- Walker Roger
- Wallace David M A
- Wallinder Hans
- Wang Liang
- Watkin Nicholas A
- Watson M E
- Waxman J H
- Waymont Brian
- Weaver Andrew
- Webb Ralph J
- Wedderburn Andrew
- Weischer Maren
- Wells Paula
- Wemyss-Holden G D
- Weston P M T
- Wheatley Duncan
- Whelan P
- Whillis D
- Whitmore Ian
- Wiklund Fredrik
- Wilde Adam D
- Wiles Vicki
- Wilkins Marie
- Wilkinson Rosemary
- Williams John H
- Williams Simon
- Willis Michael
- Wills Michael I
- Wilson J R
- Wilson Richard
- Winkler Mathias H
- Wise Marcus
- Wokozorczyk Dominika
- Wokołorczyk Dominika
- Wood Glenn
- Woodhams Simon
- Woodhouse C
- Woodward Cathryn
- Woolf [Unknown]
- Woolfenden K A
- Worlding Jane
- Wright Mark
- Wu Huihai
- WYLIE [Unknown]
- Wylie James P
- Wynne Chris
- Yeadon Trina
- Zachariah Babu
- Zang Angelika
- Zarkar A
- Zheng Wei
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2015
- Field of study
Genome-wide association studies (GWAS) have identified numerous common prostate cancer (PrCa) susceptibility loci. We have
fine-mapped 64 GWAS regions known at the conclusion of the iCOGS study using large-scale genotyping and imputation in
25 723 PrCa cases and 26 274 controls of European ancestry. We detected evidence for multiple independent signals at 16
regions, 12 of which contained additional newly identified significant associations. A single signal comprising a spectrum of
correlated variation was observed at 39 regions; 35 of which are now described by a novel more significantly associated lead SNP,
while the originally reported variant remained as the lead SNP only in 4 regions. We also confirmed two association signals in
Europeans that had been previously reported only in East-Asian GWAS. Based on statistical evidence and linkage disequilibrium
(LD) structure, we have curated and narrowed down the list of the most likely candidate causal variants for each region.
Functional annotation using data from ENCODE filtered for PrCa cell lines and eQTL analysis demonstrated significant
enrichment for overlap with bio-features within this set. By incorporating the novel risk variants identified here alongside the
refined data for existing association signals, we estimate that these loci now explain ∼38.9% of the familial relative risk of PrCa,
an 8.9% improvement over the previously reported GWAS tag SNPs. This suggests that a significant fraction of the heritability of
PrCa may have been hidden during the discovery phase of GWAS, in particular due to the presence of multiple independent
signals within the same regio
New genetic loci link adipose and insulin biology to body fat distribution.
- Author
- Aalto Ville
- Aasarød Knut
- Abecasis Goncalo R
- Abecasis Gonçalo
- Absher Devin
- Adair Linda S
- Adam Martin
- Adeyemo Adebowale
- Ahlqvist Emma
- Ahmadi Kourosh R
- Ahola Aila
- Ainali Chrysanthi
- Akylbekova Ermeg
- Ala-Korpela Mika
- Alavere Helen
- Albagha Omar M E
- Albrecht Eva
- Alen Markku
- Alexander Myriam
- Alhenc-Gelas François
- Alizadeh Behrooz Z
- Allison Matthew A
- Alonso Nerea
- Altshuler David
- Ambite Jose Luis
- Amin Najaf
- Amouyel Philippe
- An Ping
- Anderson Carl A
- Anderson Denise
- Anderson Garnet
- Andrews Jeanette S
- Antonella Mulas
- Antti Jula
- Aragaki Aaron K
- Arking Dan E
- Arnold Alice
- Arnold Alice M
- Arora Pankaj
- Arscott Gillian M
- Artigas Maria Soler
- Arveiler Dominique
- Asiki Gershim
- Aspelund Thor
- Assimes Themistocles L
- Atalay Mustafa
- Atkinson Elizabeth J
- Aulchenko Yurii
- Avery Christy
- Bain Stephen C
- Bakker Stephan J L
- Balcells Susana
- Balkau Beverley
- Ballantyne Christie M
- Balmforth Anthony J
- Bandinelli Stefania
- Barbalic Maja
- Barrett Amy
- Barroso Ines
- Barroso Inês
- Basart Hanneke
- Basart Hanneke V
- Bataille Veronique
- Baumert Jens
- Beckmann Jacques S
- Beekman Marian
- Been Latonya F
- Beilby John
- Beilby John P
- Bell Jordana T
- Bellis Claire
- Bennett Amanda J
- Bennett Franklyn
- Berenson Gerald S
- Bergman Richard N
- Bergmann Sven
- Berndt Sonja I
- Berne Christian
- Bidulescu Aurelian
- Bielak Lawrence F
- Bierut Laura J
- Biffar Reiner
- Bis Joshua C
- Blackburn Hannah
- Blangero John
- Blankenberg Stefan S
- Blüher Matthias
- Boban Mladen
- Bochud Murielle
- Boehm Bernhard O
- Boehnke Michael
- Boerwinkle Eric
- Boezen H Marike
- Bolton Jennifer L
- Bolton Judith A Hoffman
- Bonnet Fabrice
- Bonnycastle Lori L
- Boomsma Dorret I
- Borecki Ingrid
- Boright Andrew P
- Borja Judith B
- Bornstein Stefan R
- Boston Jonathan
- Bots Michiel L
- Bouatia-Naji Nabila
- Bouchard Claude
- Bovet Pascal
- Boyd Heather A
- Bragg-Gresham Jennifer L
- Brambilla Paolo
- Brand Eva
- Brand Stefan-Martin
- Brandi Maria Luisa
- Braund Peter S
- Brennan Eoin P
- Brismar Kerstin
- Brody Jennifer
- Broekmans Frank J
- Broer Linda
- Brown Matthew A
- Brown Morris J
- Brown-Gentry Kristin
- Bruinenberg Marcel
- Buchkovich Martin L
- Buckley Brendan M
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- Small Kerrin
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- Smit Johannes H
- Smith Albert
- Smith Erin N
- Smith George Davey
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- Smith Nicholas L
- Snider Harold
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- Soranzo Nicole
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- Spencer Kylee
- Srinivasan Sathanur R
- St Pourcain Beate
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- Staessen Jan A
- Stanèáková Alena
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- Stathopoulou Maria G
- Stavarachi Monica
- Stefansson Kari
- Steinle Nanette I
- Steinthorsdottir Valgerdur
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- Stolk Lisette
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- Streeten Elizabeth A
- Stringham Heather M
- Struchalin Maksim
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- Styrkarsdottir Unnur
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- Sundström Johan
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- Teumer Alexander
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- Thorand Barbara
- Thorgeirsson Gudmundur
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- Tryggvadottir Laufey
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- Tsoka Sophia
- Tsui Kim
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- Verlaan Dominique
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- Willenborg Christina
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- Williams Winfred W
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- Wilson Scott G
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- Witteman Jacqueline C M
- Wojczynski Mary K
- Wolffenbuttel Bruce H R
- Wong Andrew
- Wong Tien Y
- Woo Jean
- Wood Andrew R
- Wood Andy
- Workalemahu Tsegaselassie
- Wright Alan F
- Wu Chunyuan
- Wu Joseph M W
- Wu Ying
- Würtz Peter
- Xiao Su-Mei
- Yajnik Chittaranjan S
- Yang Jian
- Yang Qiong
- Yang Tsun-Po
- Yao Jie
- Yengo Loïc
- Yerges-Armstrong Laura M
- Young Alicia
- Young Elizabeth H
- Young J H
- Young Lauren
- Yuan Xin
- Zaboli Ghazal
- Zalloua Pierre A
- Zarrabeitia María T
- Zelenika Diana
- Zemunik Tatijana
- Zerbini Gianpaolo
- Zgaga Lina
- Zhai Guangju
- Zhang Feng
- Zhang Qunyuan
- Zhang Weihua
- Zhao Jing Hua
- Zhao Wei
- Zheng Hou-Feng
- Zheng Wei
- Zhou Yanhua
- Zhu Haidong
- Zhu Kun
- Zhu Xiaofeng
- Zhuang Wei V
- Zhuang Wei Vivian
- Ziegler Andreas
- Zillikens M Carola
- Zimmermann Martina E
- Zitting Paavo
- Zondervan Krina T
- Zukowska-Szczechowska Ewa
- Zygmunt Marek
- Ärnlöv Johan
- Österholm Anne-May
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2015
- Field of study
Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P < 5 × 10(-8)). In total, 20 of the 49 waist-to-hip ratio adjusted for BMI loci show significant sexual dimorphism, 19 of which display a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms
Finishing the euchromatic sequence of the human genome
- Author
- . Haifeng
- . Magner
- . Yin
- Abbott Scott
- Abbott-Ozersky Amanda
- Abdellah Zahra
- Abouelleil Amr
- Abrajano Anne
- Adachi Tamami
- Adam Catherine
- Adams Charles Q.
- Adamson Aaron
- Adekoya Emmanuel
- Adio-Oduola Babajide
- Aerts Andrea
- Aggarwal Arun
- Ahmadi Alireza
- Ahmed Shahana
- Aimable Matthew
- Ainscough Rachael
- Ait-Zahra Mostafa
- Aizu Tomoyuki
- Alcivare Dana
- Alegria Michelle
- Ali Alla
- Ali Johar
- Allegria-hartmann Michelle
- Alleman Jennifer
- Allen Carlana C.
- Allen Heather
- Allen Nicole R.
- Allen Susan
- Allen Thaddeus
- Almeida Jeff
- Almond Claire
- Alsbrooks Stephen L.
- Altherr Michael R.
- Amaratunge Harshinie C.
- Ambler Andrew
- Ambrose Karen
- Ambrose Kerrie
- Amemiya Chris
- Amico-Keller Gina
- Amin Amita G.
- Anderson Mechele
- Anderson Scott
- Anderson Scott
- Andora Janice
- Andredesz Carol
- Andrew Robert
- Andrews Dan
- Andrews Daniel
- Andrews Neil
- Andrews Stephanie
- Andriese Tim
- Anthouard Véronique
- Antonarakis Stylianos E.
- Anyalebechi Vivian
- Aoki Norie
- Apostolou Sinoula
- Apweiler Eva
- Arachchi Harindra
- Arai Rie
- Arbery Hazel
- Arcaina Marlon
- Arcaina Terisita
- Archer Beth
- Arellano Andre
- Arellano-Jones Perry
- Armbruster Jeff
- Armstrong Jon
- Arredondo Dilrukshi P.
- Arredondo Heather Hope
- Artiguenave François
- Asakawa Shuichi
- Asakawa Teruyo
- Ash Gareth
- Ashcroft Kevin
- Ashurst Jennifer
- Ashwell Robert
- Ashworth Linda K.
- Aslanidis Cara
- Asomugha Chinwe O.
- Asuncion Lawreen
- Atkin Deborah
- Atkinson Andrea
- Atkinson Barry
- Attix Cristina
- Attwood John
- Aubin Keith
- Auger Katherine
- Austin Shannon Michelle
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- Bates Karen
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- Batzer Mark
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- Baumohl Jason
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- Bayul Tashi
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- Bituin Aleksandr
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- Goyette Audra
- Grady Deborah I.
- Grady Michelle L.
- Grafham Darren
- Graham Joe
- Grandbois Edward
- Grant Jennifer
- Grant Michael
- Grant Susan
- Graves Tina A.
- Gray Bruce
- Gray Emma
- Gray Lain
- Green Lisa
- Greenhalgh James
- Greenhill Joe
- Gregg Philippa
- Gregory Simon
- Grewal Nennu
- Gribble Susan
- Griffith Jeffrey K.
- Griffiths Coline
- Griffiths Ed
- Griffiths Mark
- Griffiths-Jones Sam
- Grigoriev Igor
- Grimwood Jane
- Grocock Russell
- Groza Matthew
- Gu Jingli
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- Gu Jun
- Gu Wenyi
- Gu Wenyi
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- Guarin Hannibal
- Guel Metzalli
- Guerra William
- Guevara Whitney V.
- Gui Qi
- Gunaratne Preethi
- Gunning Kate
- Guo Daorong
- Guo Jane
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- Gustafson Erik
- Guthrie Ian
- Guyer Mark
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- Ha Chi
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- Hajek Patrick
- Hall Brett Lynn
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- Hamada Junko
- Hamilton Cerissa
- Hamilton Keelan A.
- Hamilton Matt
- Hamlett John
- Hamlett John
- Hammon Nancy
- Hammond Martin
- Hammond Sha
- Hammond Sian
- Hamza Khalid
- Han Guiqing
- Han Shunsheng
- Han Xurong
- Hanak Vincent A.
- Hancock Julie
- Harbes Brandy A.
- Harding Adam
- Harkins C. Richard
- Harley Joanne
- Harper David
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- Hashimoto Etsuko
- Hashimoto Wakako
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- Haugen Eric
- Haussler David
- Havlak Paul
- Hawes Alicia C.
- Hawkins Ebere Sylvia Onyirioha
- Hawkins Natalie
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- Hewitt Stephen
- Heyen Joshua
- Higgs Douglas
- Hildebrand Carl E.
- Hillier LaDeana
- Hillyard Guy
- Hines Sandra
- Hinkins Russell
- Hinrichs Angela S.
- Hitchens Matthew Edward
- Ho Issac
- Ho Sara-Jane
- Hodgson Anne V.
- Hodgson David
- Hoffman Susan M.G.
- Hoffs Michael
- Hogues Marilyn E.
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- Holtzer Caleb
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- Homsi Farah J.
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- Idlebird Devincent G.
- Iliev Ilian
- Imbro Paula
- Imo Kelvin C.
- Inacio Nicole
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- Ince Michael
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- Ishibashi Akiko
- Ishikawa Sabine K.
- Ishizaki Hinako
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- Izatt Janet
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- Jackson Terri
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- Jaeger Sara
- Jaffe David B.
- Jahn Niels
- Jaklevic Joseph
- Jaklevic Michael
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- Jeffery Grant
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- Jewett Phillip E.
- Jia Jia
- Jia Jia
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- Jiang Lu
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- Jones Myrna D.
- Jones Steven
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- Keenan Stephen
- Kegelmeyer Laura
- Kegg Lisa
- Kelley Simon
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- Kelly Shayna P.
- Kelly Susan H.
- Kershaw Joanna
- Kettleborough Ross
- Keys David
- Khan Arsi
- Khan Umer F.
- Khan Ziad Mohid
- Khine Susu
- Khurama Divya
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- Kong Yi
- Korf Ian
- Kosiura Anna
- Kou Zhaohui
- Kovar Christie L.
- Krawczyk Marie-Claude
- Kremitzki Colin
- Kremmidiotis Gabriel
- Krogh Anders
- Kronmiller Brent
- Kruchowski Scott S.
- Kube Michael
- Kubischta Duane
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- Lamar Betty
- Lambart Christine
- Lamble Ralph
- Lamerdin Jane E.
- Lander Eric S.
- Landers Tom
- Langford Cordelia
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- Lao Victoria
- Lapidus Alla
- Larke Ben
- Lato Bernadette
- Latreille Phil
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- Lei Meng
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- Levan Jaclyn M.
- Leversha Margaret
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- Lewis Doreen
- Lewis Ernest K.
- Lewis Keith
- Lewis Lakeshia C.
- Lewis Lora R.
- Lewis Tammy
- Leyba Tina
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- Lindblad-Toh Kerstin
- Lindo Ken
- Lindquist K.
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- LIne Matthew
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- Longmire Johnathan L.
- Lopez Frederick
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- Lorensuhewa Lorna M.
- Lou Yunian
- Loulseged Hermela
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- Lovell Jamie
- Lovett Demetria A.
- Lowenstein Michael G.
- Lowry Stephen
- Lozado Ryan J.
- Lu Lingfeng
- Lu Tao
- Lu Xiuhua
- Lu Yongxiang
- Lu Yontao T.
- Lu Yue
- Lucas Robert
- Lucas Susan
- Lucier Alice
- Lucier Raymond L.
- Ludeman Thom
- Lui Annie
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- MacLean Christine
- Madabhushi Ramki
- Madu Renita C.
- Maeda Hideto
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- Maheshwari Manjula
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- Maltbie Mary I.
- Mangum Brian
- Manning Jonathan
- Manohar Chitra
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- Mardis Elaine R.
- Mareth David
- Mariano Marisa
- Marinelli Lisa
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- Marquis-Homeyer Catherine
- Marr Thomas G.
- Marra Marco
- Marriott Neil
- Marrone Anne
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- Matthews Lucy
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- Matthews Paul
- Matthews Sterling D.
- Mauceli Evan
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- McLeod Michael P.
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- McMurray Amanda
- McMurray Des
- McMurray Kimberly
- McMurray Kimberly L.
- McNinch Jenny
- McPherson John
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- McVicker Graham
- McWilliams Natalie
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- Meidi Patrick
- Meier Elke
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- Mejima Mio
- Meldrim James
- Melsopp Craig
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- Meng Shanshan
- Menuge Noel
- Mercado Christian
- Mercado George
- Mercado Iracema C.
- Mercer Simon
- Merritt Christina E.
- Mesirov Jill P.
- Metzker Michael Lee
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- Miller Christie
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- Miner Sheri
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- Morgan Margaret B.
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- Moyzis Robert K.
- Mu Feng
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- Mullenger Ian
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- Munday Brian
- Munday Elaine
- Mundt Mark O.
- Mungall Andy
- Munidasa Mala
- Munk A. Christine
- Munk Christie A.
- Munson Glen
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- Murayama Yuji
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- Murphy Michael
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- Nagamine Kentaro
- Nagao Syunsuke
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- Nair Latha
- Nair Seema R.
- Naka Maho
- Nakagawa Masayo
- Nakagawa Saori
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- Nankervis Colin E.
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- Nazareth Lynne V.
- Neal Dearl D.
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- Nelson Deborah A.
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- Nowlin Larry
- Nusbaum Chad
- Nwaokelemeh Ogechi O.
- Nwokenkwo Stanley
- O\u27Donnell Paula
- O\u27Donovan Daniel
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- O\u27Loughlin Jennifer
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- Okui Michiyo
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- Okwuonu Geoffrey O.
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- Olivas Jason
- Oliver Hayley
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- Olson Maynard V.
- Omotosho Bamidele
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- Ovcharenko Ivan
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- Oviedo Rodolfo J.
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- Ozersky Philip
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- Parkin Kim
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- Pasternak Shiran
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- Patel Vishal V.
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- Paul Heidie A.
- Paul Shelia
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- Payton Brett A.
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- Pearman Charlene
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- Perez Agapito
- Perez Lesette M.
- Perito Andrew
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- Pollard Martin
- Polman Jos
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- Porter Keith
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- Prathalingham Radhika
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- Qiao Zhenyong
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- Radionenko Maxim
- Rajagopal Mohan
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- Richardson Susan
- Ricke Darryl O.
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- Riethman Harold
- Riethoven Lyn
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- Rise Cecil
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- Rives Catharine M.
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- Sarmiento R.
- Sasaki Takashi
- Satpathy Suraj
- Saunders David
- Saunders Elizabeth H.
- Saurin William
- Savery Glenford G.
- Sawada Nori
- Sawhill William W.
- Saxman Eric
- Scarpelli Claude
- Scharfe Maren
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- Scherer Steven Edward
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- Skuce Carl
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- Sonnhammer Erik
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- Stalvey Malinda
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- Steingruber Helen
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- Su Xiaohu
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- Subramanian Sandhya
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- Sulston John
- Summers Leslie J.
- Sun Hui
- Sun Jiajia
- Sun Jiandong
- Sun Jiu Qin
- Sun Min
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- Sun Wei
- Sun Yongqiao
- Sun Yu
- Sun Yue
- Sutherland Grant R.
- Sutherland Robert D.
- Sutton Angelica E.
- Svatek Amanda F.
- Svetz Jessica
- Svetz Leah Anne
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- Swann Mark
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- Tacey Kristina
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- Tam Serena
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- Tamirisa Aparna
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- Tatum Owatha I.
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- Taylor Gillian
- Taylor Kate
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- Telford Ethan Brett
- Tenzin Pema
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- Terry Astrid
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- Tesmer Judith G.
- Tester Julieanne
- Thayer Nina
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- Theil James
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- Thexton David
- Thies Stephanie
- Thomas Craig
- Thomas Daniel
- Thomas Daryl J.
- Thomas Karen
- Thomas Nicole
- Thomas Paulette
- Thomas Ruth
- Thomas Shereen
- Thommai Roselin
- Thompson Linda S.
- Thorne Rachel Diane
- Thorpe Andrea
- Thorpe Karen
- Thoulutsang Yama
- Threadgold Glen
- Thurston Scott
- Tian Chaoguang
- Tian Chaoguang
- Tian Wei
- Tian Yan
- Tian Yong
- Tian Yuqing
- Tice Hope
- Tighe Damon
- Tin-Wollam Aye M.
- Tinsley Emma
- Tochigi Miwako
- Togashi Naoko
- Tomizawa Iori
- Tomlinson Chad
- Tong Jingli
- Topham Kerri
- Torcaso Bill
- Torney David C.
- Totoki Yasushi
- Towey Sarah
- Toyoda Atsushi
- Tracey Alan
- Tran Ly Thanh
- Tran-Gyamfi Mary
- Trani Lee
- Trankiem Margie
- Trask Barbara J.
- Travers Johnathan
- Trejos Zulma Y.
- Treuhaft Marianne
- Trevino Brenda Kaye
- Tromans Anthony
- Trong Stephan
- Trumbower Heather
- Tsai Ming
- Tsamla Tsamla
- Tsolas Jason
- Tsomo Nawang
- Tsujimoto Susan
- Tsukamoto Yumi
- Tsuruoka Hiromi
- Tsuzuki Rina
- Tu Yuefeng
- Tu Yuefeng
- Tubby Ben
- Tufarelli Cristina
- Turner Heidi
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- Tynan Katherine
- Ueland Stephanie
- Ueng Samantha
- Ukegbu Ogechi Nkemdirim
- Ulanovsky Levy E.
- Un Chun
- Ung Quyen
- Upson Darren
- Urban Jeremy B.
- Ureta-Vidal Abel
- Ureta-Vidal Abel
- Usmani Kamran
- Ustaszewska Anna
- Uyama Nozomi
- Valas Ruben E.
- Valdez Michelle
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- Vartanian Steffan
- Vasquez Lydia I.
- Vassiliev Helen
- Vastrik Imre
- Vaudin Mark
- Veil Rose
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- Velasco Nelson
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- Vera Virginia A.
- Verduzco Daniel
- Vergez Lisa
- Vico Virginie
- Viknaraja Ramya
- Villasana Donna M.
- Vine Wendy
- Viswanathan Vijay
- Vo Andy
- Vo Nu
- Voak Paul
- Vollenhoven David
- Wada Hiromi
- Wagner Mark
- Wagner-McPherson Caryn
- Waldron Lenee
- Waligorski Jason E.
- Walker Davian L.
- Walker Keya
- Walker Sarah
- Wall Melanie
- Wall Randy E.
- Wallace John
- Wallis Justine
- Wallis Michelle
- Walsh Jennifer
- Walsham Natalie
- Wan Ma
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- Wang Dong
- Wang Feng
- Wang Guangxin
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- Wang Guihai
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- Wang Huifeng
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- Wang Jian
- Wang Jian
- Wang Jie
- Wang Jing
- Wang Jingqiang
- Wang Jingqiang
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- Wang Jun
- Wang Jun
- Wang Li
- Wang Lijie
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- Wang Lijun
- Wang Ling
- Wang Liqun
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- Wang Shifen
- Wang Shu
- Wang Suzhen
- Wang Wenjun
- Wang Xiaoling
- Wang Xiaoning
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- Wang Xuegang
- Wang Yan
- Wang Yimin
- Wang Ying
- Wang Ying
- Wang Yuanyuan
- Wangchuck Tsering
- Wangdi Tsering
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- Warren Graham
- Warren James T.
- Warry Georgina
- Watanabe Hidemi
- Watanabe Saki
- Waterston Robert H.
- Watson Andy
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- Webb Jeannette
- Webber Caleb
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- Wehri Edward
- Wei Shulin
- Wei Xuehong
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- Wells Sarah
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- West Tony
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- Wheatley Carl
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- Wheeler Gideon
- Wheeler Jeremy
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- White Scott P.
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- Whitmore Scott
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- Wickremasinghe Manosha I.
- Widaa Sara
- Wiegel Sarah
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- Wilkinson Jane
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- Williams Andy
- Williams Bill
- Williams Gabrielle A.
- Williams Leanne
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- Williamson Helen
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- Wills Richard
- Wilmer Tamsin
- Wilming Laurens
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- Wilson Gareth
- Wilson Margaret
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- Womack Andrew W.
- Wong Benjamin
- Wong Gane K-S
- Wood Diane
- Wood Emma
- Wood Joe
- Wooden Hailey S.
- Wooden Steven H.
- Woodeson Sharon
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- Wooster Richard
- Worley Kim Carlyle
- Woyke Tanja
- Wray Matthew
- Wray Paul
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- Wright Debbie
- Wright Kathrine
- Wright Kristin
- Wright Rita A.
- Wu Chungen
- Wu Dongying
- Wu Jiaqian
- Wu Jung-Rung
- Wu Kevin
- Wu Qingfa
- Wu Qingfa
- Wu Ruiming
- Wu Xiao
- Wu Xiaojing
- Wu Zaining
- Wyatt Julia
- Wycoff-Montenegro Melissa
- Wylie Kris
- Wyman Dudley
- Wyman Stacia
- Xi Yan
- Xi Yingying
- Xie Fei
- Xie Gary
- Xie Jane
- Xiong Hui
- Xiong Yuqing
- Xu Alex
- Xu Jing
- Xu Jing
- Xu Ruqin
- Xu Shuhua
- Xu Wei
- Xu Xinlai
- Xu Yan
- Xu Yuning
- Xu Zhihong
- Xu Zuyuan
- Xuan Yali
- Xuan Zhenyu
- Xue Rui
- Yada Tetsushi
- Yadav Shailendra
- Yakub Syed
- Yamamoto Lynn
- Yamamoto Noriko
- Yamamoto Yuko
- Yamashita Yasue
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- Yang Huanming
- Yang Huanming
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- Yang Shiaw-Pyng
- Yang Shudong
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- Yang Xiaonan
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- Yao Zhijian
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- Ye Chen
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- Yun Rui
- Zainoun Joanne
- Zembeck Lisa
- Zeng Yixin
- Zhai Dong
- Zhan Guoping
- Zhang Bo
- Zhang Caimin
- Zhang Fengmei
- Zhang Guangyu
- Zhang Guohua
- Zhang Guohua
- Zhang Haiqing
- Zhang Haiqing
- Zhang Haiqing
- Zhang Hongbo
- Zhang Hongbo
- Zhang Jingjing
- Zhang Jingjing
- Zhang Jingkun
- Zhang Jiuchun
- Zhang Jiuchun
- Zhang Lanzhi
- Zhang Li
- Zhang Li
- Zhang Meihua
- Zhang Meng
- Zhang Ming
- Zhang Qing
- Zhang Ruhua
- Zhang Shaojie
- Zhang Tiezhen
- Zhang Wei
- Zhang Wei
- Zhang Xianglin
- Zhang Xianglin
- Zhang Xiaoliang
- Zhang Xiuqing
- Zhang Yan
- Zhang Yi
- Zhang Yilin
- Zhang Yilin
- Zhang Ying
- Zhang Yuansen
- Zhang Yuzhi
- Zhang Zhengdong
- Zhao Hongmei
- Zhao Lijian
- Zhao Shenru
- Zhao Zhijing
- Zhen Zhicheng
- Zheng Haibo
- Zhong Ming
- Zhou Carol
- Zhou Haixia
- Zhou Jianling
- Zhou Nannan
- Zhou Xinfeng
- Zhou Yan
- Zhou Yang
- Zhou Yi
- Zhu Bingying
- Zhu Bofeng
- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
- Zhu Yongge
- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
Large expert-curated database for benchmarking document similarity detection in biomedical literature search
- Author
- Aanei Carmen M.
- Abid Muhammad B.
- Abramowitz Matthew K.
- Abu-Zaid Ahmed
- Adamo Vincenzo
- Adeyemo Adebolajo A.
- Afnan Masoud
- Agarabi Cyrus
- Aggelidou Maria
- Ahmad Haroon
- Ahmad Rafi
- Aizat Wan M.
- Ajani Penelope A.
- Akinwumi Sayo A.
- Al-Farha Abd A.
- Al-Lawama Manar
- Al-Owaifeer Adi M.
- Al-Riyami Arwa Z.
- Alanio Alexandre
- Alaux Cedric
- Albery Gregory F.
- Albiol Joan
- Albrecht Dirk R.
- Albuquerque Lucia G.
- Alhowimel Ahmed
- Ali Junaid
- Alimba C.G.
- Allardyce Judith
- Almeida Gabriel M.F.
- Alonso-Caneiro David
- Alper Ozgul M.
- Alshehri Mansour
- Alsuhaibani Mohammed
- Alzghari Saeed K.
- Amer Said E.D.R.
- Amir Shimon
- Amiya Eisuke
- Ammerman Brooke A.
- Amorim Rogerio M.
- An Qianli
- Anazodo Udunna C.
- Andersen Stig U.
- Andersen Vibeke
- Angus Kathryn
- Anikin Andrey
- Aplin John D.
- Argyropoulos Christos
- Armitage Charles
- Asaduzzaman Muhammad
- Asady Hadi
- Ascher David B.
- Ashry Mohamed
- Asmann Yan W.
- Assaeed Abdulaziz M.
- Atack John M.
- Atanasov Atanas G.
- Atchison David A.
- Atkins Gerald J.
- Atlas Lauren
- Ato Dai
- Avery Simon V.
- Avillach Paul
- Azubuike Samuel O.
- Baade Peter D.
- Bach-Mortensen Anders
- Backman Lars
- Badie Christophe
- Bae Taeok
- Bagloee Saeed Asadi
- Bai Xiaoyong
- Baier Dirk
- Bail Kasia
- Baines Rebecca L.
- Baker Chris I.
- Bakkach Joaira
- Baldi Alfonso
- Ball Elizabeth
- Ballantyne Maghan
- Baltiansky Lior
- Ban Bo
- Bannon Ross
- Bansal Abhisheka
- Bar Ido
- Bardot Olivier
- Barnett Adrian G.
- Barraud Pierre
- Bartas Martin
- Basharat Zarrin
- Basner Mathias
- Bathelt Joe
- Batra Jyotsna
- Baumert Philipp
- Bazanova O.M.
- Beale Andrew
- Beck Charles R.
- Beck Jill
- Becker Daniel
- Beddoe Travis
- Belachew Kiflemariam Y.
- Bell Melanie L.
- Ben-Nafa Walid
- Benezeth Yannick
- Bengtsson-Palme Johan
- Benkeser David
- Berbesque Colette
- Berezikov Eugene
- Bergsland Niels
- Berners-Price Sue
- Bernhardt Peter
- Bernier Meghan L.
- Berrevoet Frederik
- Berry Edward
- Berthold Maximilian
- Bessa Theolis B.
- Beyene Tariku J.
- Bhardwaj Vivek
- Biedermann Peter H.W.
- Bijleveld Erik
- Billington Craig
- Binder Karin
- Birch John
- Bittner Florian
- Bitzer Michael
- Black Emma
- Blakely Randy D.
- Blanchard Adam M.
- Blancher Antoine
- Blanck Oliver
- Bland Nicholas S.
- Blankstein Ron
- Blaskovich Mark A.T.
- Bleackley Mark
- Blombach Fabian
- Blum Robert
- Boah Michael
- Boakye Dominic W.
- Bodagh Neil
- Boehme Karen A.
- Boelaert Marleen
- Bogdanos Dimitrios
- Bonatsos Vasileios
- Bonvin A.M.J.J.
- Boon Michele H.
- Borges Paulo
- Bosch Carles
- Bosch Oliver
- Bouboulis George
- Boudreau Shellie A.
- Bourgoin Thierry
- Bourke Emer
- Bouvard Daniel
- Boykin Laura M.
- Br\ufchl Albert
- Bradley Graeme
- Bradshaw William
- Bramoweth Adam D.
- Brand Thomas
- Braubach Oliver
- Braun Daniel
- Braun R. J.
- Brenneisen Peter
- Bridges Kristina M.
- Bromfield Elizabeth
- Brooks Anastasia
- Brown James A.L.
- Brown Joshua
- Brown Peter
- Browngardt Christopher
- Brownlie Jeremy
- Brox-Ponce Josue
- Brunetti Arturo
- Bukowy-Bieryllo Zuzanna
- Bul Kim C.M.
- Bull James A.
- Bullen Benjamin
- Burt Austin
- Burton Kathryn J.
- Bush Stephen J.
- Butkowski Eugene G.
- Butler Lisa M.
- Byrareddy Siddappa N.
- Byrne Hugh J.
- Cabantous Stephanie
- Cai Yufeng
- Calabr\uf2 Giovanna E.
- Calatayud Sara
- Callahan Tiffany J.
- Campana Luca G.
- Campbell Matthew
- Candal Eva
- Canham Colin D.
- Cao Bing
- Cao Zanxia
- Cao Zehong
- Cardoso Pedro
- Carlson Kimberly
- Carninci Piero
- Carroll Grace
- Carter Dee
- Carvajal Richard
- Cascella Marco
- Casillas S\uf2nia
- Castelvetro Valter
- Caswell Patrick T.
- Catry Thibault
- Cavalli Giacomo
- Cernava Tomislav
- Cerovsky Vaclav
- Ch\ue1vez-Fumagalli Miguel A.
- Chacko George
- Chagoyen Monica
- Chakraborty Sayan
- Chalmers Kelsey
- Chan Sherwin S.
- Chandrasekaran Arun R.
- Chang Shun C.
- Chang Wei
- Chao Fengqing
- Chao Jie
- Charrier Elisabeth E.
- Chatterjee Pranab
- Chatzitheochari Stella
- Che Zhengping
- Chen Andrew T.Y.
- Chen Branson
- Chen Chang-Er
- Chen Chang-Shi
- Chen Dong F.
- Chen Haimin
- Chen Hao
- Chen He
- Chen Huaming
- Chen Hui
- Chen Jui-Tung
- Chen Liming
- Chen Xiaoyin
- Chen Xin
- Chen Yi-Chun
- Chen Yinglong
- Chen Youning
- Chen Yu-Chih
- Chen Zhao
- Cheng Changxiu
- Cheng Jianlin
- Cheng Shuiqin
- Chenguang [NO FIRST NAME IN SCOPUS]
- Cheung Johnny T.K.
- Chhatriwalla Adnan K.
- Chikowe Ibrahim
- Chinapaw Mai
- Chinopoulos Christos
- Cho William C.S.
- Choi Jane R.
- Choi Youngrok
- Chong Lillian
- Chowdhury Debashish
- Chowdhury Mohiuddin A.K.
- Christensen Martin R.
- Christoffersen Tore
- Chuang Trees-Juen
- Chung Hee-Jung
- Chwalibog Andre
- Ciresi A.
- Cobine Paul A.
- Cockcroft Shamshad
- Coelho Luis P.
- Colella Vito
- Collevatti Rosane G.
- Comel Jo\ue3o C.
- Conesa Ana
- Conway Aaron
- Cook Penny A.
- Cooke Robert S.C.
- Cooper David N.
- Cooper Jeffrey
- Coqueret Olivier
- Corea Enoka M.
- Cornejo Diego A.V.
- Cosacak Mehmet I.
- Cosse Cyril
- Costa Antonio
- Costa Bruno M.
- Costa Elisio
- Costa Vincent D.
- Cottini Marzia
- Coupland Carol
- Covington Natalie V.
- Crawford Stephanie Y.
- Cruz Aparecido D.
- Cu\uedv P\ue1raic O.
- Cuenda Ana
- Cui Huijuan
- Cui Qiang
- Cui Yanru
- Culver David C.
- Cunningham Catriona
- Cuypers Maarten
- Cyr Normand
- D\u27Angiulli Amedeo
- Dahms Tanya E.S.
- Dai Zhanwu
- Daigle France
- Dalgleish Raymond
- Dalrymple Brian P.
- Danchin Antoine
- Danielsen H\ue5vard E.
- Dao Myriam
- Darras S\ue9bastien
- Dauga Delphine
- Daulatabad Swapna V.
- Davidson Sean M.
- Day David A.
- de Keersmaecker Kim
- de Leeuw Frank-Erik
- de Maio Nicola
- Dean Lorraine T.
- Debrabant Birgit
- Degirmenci Volkan
- Del Tredici Andria L.
- Delahay Robin M.
- Delarocque Julien
- Demaison Luc
- Deng Zaian
- Denzel Martin S.
- Deschodt Mieke
- Devkota Hari P.
- Devkota Kiran
- Devos Lucie
- Devriendt Koenraad
- Dhar Aurup R.
- Dhariwal Raman
- Dhaval [NO FIRST NAME IN SCOPUS]
- Diao Jiajie
- Ding Jiandong
- Ding Ke-Feng
- Dings Ruud P.M.
- Diodato Daria
- Diouf Barthelemy
- Dixon Ray
- Dlamini S.V.
- Doan Lisa V.
- Dogan Yunus
- Domingues Helena S.
- Dong Kexian
- Dong X.C.
- Dong Zheng
- Donner Claudio F.
- Dono Marcos
- Doxey Andrew C.
- Dressick Walter
- Drevon Christian A.
- Dreyer Niklas
- Duan Huiling
- Ducho Christian
- Ducommun Bernard
- Dudley Kevin J.
- Duffey Maelle
- Dufies Maeva
- Duijf Pascal H.G.
- Dumaz Nicolas
- Dutt Avik
- Dwarakanath Bilikere S.
- Ebell Mark H.
- Echeverr\ueda Natalia
- Ecke Thorsten
- Eckweiler Denitsa
- Eerola Tuomas
- Effiong Andem
- Egea Luis G.
- Ehret Felix
- Eisenhardt Steffen
- Eixarch Elisenda
- Ekstrand Chelsea
- El-Adawy Hosny
- El-Esawi Mohamed A.
- El-Said Mohammed
- Elewa Yaser H.A.
- Elkum Naser
- Emmrich Julius V.
- Engel Michael S.
- Engel Nadja
- Epp Trevor
- Erickson Timothy B.
- Esfahlani Shabnam S.
- Eskelinen Eeva-Liisa
- Eskew Evan A.
- Esnakula Ashwini K.
- Eustace Alex J.
- Evangelou Evangelos
- Fairhead Michael
- Falk Sebastian
- Fallah Mazyar
- Falter-Wagner Christine M.
- Fan Dongsheng
- Fan Xiao
- Farber Debora B.
- Fardet Tanguy
- Farhoudi Ramin
- Faruk Mohammed
- Faville Marty J.
- Faye Martin
- Feghali Karine A.
- Feifei Shi
- Fejzo Marlena S.
- Feleke Berhanu E.
- Ferguson Trevor S.
- Fernandez-Fernandez Beatriz
- Fernandez-Triana Jose
- Festa Fernanda
- Feteira Antonio
- Feurer Thomas
- Feyerabend Frank
- Fierz Walter
- Filipp Fabian
- Flegel Willy A.
- Fleres Francesco
- Flood-Page Patrick
- Florio Tullio
- Foley Kieran G.
- Forano Evelyne
- Forsayeth John
- Foster Emma J.
- Foster Stephen
- Founou Luria L.
- Fox Simon A.
- Franks Steven J.
- Freitas Angela
- Frentiu Francesca D.
- Friebe Michael
- Frilander Mikko J.
- Fu Fan
- Fu Xinmiao
- Fujita Satoshi
- Furer Tzvi
- Furuta Saori
- Fuss Johannes
- Gabrielsen Mads
- Gadelkareem Rabea A.
- Gajda Maksymilian
- Galea Ian
- Galimov Evgeny
- Galluzzi Luca
- Gani Federica
- Ganpule Arvind P.
- Gao Jianzhao
- Gao Tian
- Gao Yibo
- Garc\ueda-Alix Antonio
- Garcia-Rivera Enid J.
- Garip Gulcan
- Gatchell Michael
- Gaullier Guillaume
- Gazdar Adi
- Gebremedhin [NO FIRST NAME IN SCOPUS]
- Gedye Kristene
- Gelfer Yael
- Gemmill Alison
- George Ronald B.
- Ghelardi Emilia
- Ghosh Sayantan
- Gianchecchi Elena
- Giganti Francesco
- Gill Martin R.
- Gilliham Matthew
- Giordano Maurizio
- Giunta Cecilia
- Gladue Douglas P.
- Gleason Joshua M.
- Gleeson Paul A.
- Gloyn Liz
- Gnasso Agostino
- Goarant Cyrille
- Gobet Ang\ue9lique
- Goggs Robert
- Gong Haipeng
- Gonz\ue1lezlez-Prendes Rayner
- Goodin Amie
- Goodyear Carl S.
- Gora Diop
- Gough Michael J.
- Gouil Quentin
- Govender Pragashnie
- Govinden Usha
- Goyal Ravinder
- Gr\ue9bert Th\ue9ophile
- Gr\ufcneberg Patrick
- Grabowski Piotr
- Graham Emily B.
- Graham Kathryn E.
- Grande-P\ue9rez Ana
- Graves Patricia M.
- Greene Garrett
- Greenwald Noah F.
- Greidanus Harm
- Greiff Victor
- Grey James
- Grice Darren
- Gridneva Zoya
- Grimm Dominik G.
- Groen Ewout J.N.
- Grothe Michel J.
- Gruber Jens
- Grunau Christoph
- Grundle D.S.
- Grybos Malgorzata
- Guerra-Mora Jos\ue9 R.
- Guerrero Fabricio
- Guignard L\ue9o
- Guisado J.L.
- Gumede Nicksy
- Gumulya Yosephine
- Guo Chengying
- Guo Xinyi
- Guo Yabin
- Gupta Himanshu
- Gurevich Vsevolod V.
- Gurney-Champion Oliver J.
- Gusev Oleg
- Guti\ue9rrez-Sacrist\ue1n Alba
- H\ufcttner Felix J.
- Habes Mohamad
- Hacker Elke
- Hackshaw Allan
- Haenssgen Marco J.
- Hage Steffen R.
- Hagen Guy
- Hahn Steven
- Hall Adam
- Hall Richard
- Haller Dagmar M.
- Hammerschmidt Sven
- Han Hyemin
- Han Jianwei
- Han Qian
- Han Renzhi
- Handfield Martin
- Hanson Jack
- Haore Gbaguidi
- Hapuarachchi Hapuarachchige C.
- Harder Timm
- Hardingham Jennifer E.
- Harper Paul
- Harrison Pille
- Hartmann Marcus D.
- Harvey David J.
- Hasler David
- Haston Scott
- He Shuonan
- Heck Michelle
- Heers Marcel
- Heffler Enrico
- Heijne Marloes
- Heinemann Stephanie
- Heinrich Michael
- Helanter\ue4 Heikki
- Herbelet Sandrine
- Hew Khe F.
- Higginbottom Daniel B.
- Higuchi Yohei
- Hilaire Cynthia St.
- Hilton Rachel
- Hiroi Noboru
- Hobbs Emma
- Hodzic Enisa
- Hoenner Xavier
- Hogg William E.
- Hogrebe Alexander
- Hojsgaard Diego
- Holgate Joan Y.
- Hone Andrew
- Hongoh Yuichi
- Honjo Ken
- Horbar Jeffrey
- Hori Hikaru
- Hu Guoku
- Hu Pingzhao
- Huang Ancheng
- Huang Guangqun
- Huang Zhengping
- Huber Heinz P.
- Huber Michael
- Hueso Luis E.
- Huirne Judith
- Hulse-Kemp Amanda M.
- Hunter Kylie E.
- Hurt Lisa
- Idborg Helena
- Ide Kazuki
- Ijzerman Adriaan P.
- Ikeo Kazuho
- Ikonomopoulou Maria P.
- Ingley Evan
- Iskander-Rizk Sophinese
- Iyer Lavanya M.
- J\ue9gousse Clara
- Jahan Yasmin
- Jakeman Philip M.
- James Ameh S.
- Janga Sarath C.
- Janzen Thijs
- Jayaraman Jayakumar
- Jean-Quartier Claire
- Jeltsch Albert
- Jensen Arne
- Jeon Sang-Min
- Jesus Carlos
- Jeurissen Patrick
- Jia Hong
- Jia Husen
- Jia Shuqin
- Jia Yangyang
- Jian Gao
- Jiang Fan
- Jiang Jianping
- Jiang Xingyu
- Jibb Lindsay A.
- Jin Yi
- Jo Daehyun
- Joel Emmanuel
- Joffroy Bastian
- Johnson Andrew M.
- Johnson Daniel M.
- Johnston Marie
- Jongen Stefan
- Jonscher Karen R.
- Jorens Philippe G.
- Jorgensen Jens O.L.
- Josse Claire
- Joubert Johan W.
- Jung Sin-Ho
- Junior Antonio M.
- Jurman Giuseppe
- Jutzeler Catherine
- Kabra Dhiraj
- Kahan Thomas
- Kaiser Stefan
- Kalatzis Panagiotis
- Kamagata Koji
- Kamboj Sunjeev K.
- Kambondo George
- Kamiya Haruyuki
- Kane Nolan C.
- Kang Yong-Kook
- Kanj Souha S.
- Karamanos Yannis
- Karim Masud
- Karmakar Chandan
- Karnati Priyanka
- Karp Natasha A.
- Karsay Kathrin
- Kasian Olga
- Kauppila Joonas H.
- Kaur Harsheen
- Kaya Cihan
- Kaye Linda K.
- Ke An
- Keitel Anne
- Kelly Daniel
- Kelly Ryan
- Kelly Sarah
- Kelly Shona
- Kempe Andreas
- Kenna Ralph
- Kennedy Jonathan
- Keown Jeremy R.
- Kersten Birgit
- Khalaf Roy A.
- Khalid Javaria M.
- Khan Murad M.
- Khatlani T.
- Kheir Fayez
- Khider Tarig
- Khoo Chin M.
- Khwaja Nyil
- Kichatova V.S.
- Kickert Rob
- Kidibule Peter E.
- Kieselmann Jennifer P.
- Kievit Rogier A.
- Kijanka Gregor S.
- Kim Hyeon J.
- Kim Yong-Min
- King Sarah R.B.
- Kinyanjui Timothy
- Kiraǧ N\ufckhet
- Kish J.K.
- Kitazawa Takeshi
- Kiyani Musa
- Klein Reinhild
- Klempnauer Karl-Heinz
- Kleppe Andreas
- Klump Hannes
- Kluz Tomasz
- Knox Paul
- Kobayashi Tatsuya
- Kobold Sebastian
- Koch Karl-Wilhelm
- Kohanbash Gary
- Kohls Gregor
- Kohonen-Corish Maija R.J.
- Koleva-Kolarova Rositsa G.
- Kong Xiangpeng
- Konkle-Parker Deborah
- Korpela Kalevi M.
- Kosanic Sasha
- Kostrikis Leondios G.
- Koutoukidis Dimitrios A.
- Kovesi Tom
- Kraiczy Peter
- Kramer Paul
- Kraschnewski Jennifer L.
- Kratz Harald
- Krause G\ufcnter
- Krebsbach Paul H.
- Kristensen S\uf8ren R.
- Kristiansson Erik
- Kueberuwa Gray
- Kugler Jan-Michael
- Kulkarni Ameya
- Kumar Addanki P.
- Kumar Dilip
- Kumar Gyanendra
- Kumar Narendra
- Kumar Nitin
- Kumari Prerna
- Kunimatsu Akira
- Kurdak Hatice
- Kurgan Lukasz
- Kurniawan Nicholas A.
- Kwon Young D.
- Labutin Dmitry
- Lachat Carl
- Lacy-Colson Jon
- Lagisz Malgorzata
- Lai Hei M.
- Laky Brenda
- Lalaouna David
- Lamberts Aniek
- Lammerding Jan
- Lange Matthias
- Lanza Giuseppe
- Larrosa Mar
- Laslett Andrew L.
- Latif Asam
- Lau Colleen L.
- Lauschke Volker M.
- Laverman Gozewijn D.
- Lazo-Langner Alejandro
- Le Thuc D.
- Leclair Elizabeth E.
- Leclercq Guy
- Lee Kyung-Woo
- Lee Ming-Yih
- Lee Moon-Soo
- Lee Senhong
- Leem Jung W.
- Leightley Daniel
- Leite Andreia
- Lercher Lukas
- Lewis James S.
- Li Bingling
- Li Genyuan
- Li Jian
- Li Jiansheng
- Li Jiuyong
- Li Maoteng
- Li Qingchun
- Li Tangliang
- Li Ying
- Li Yongzhe
- Li You
- Li Zhixiu
- Liang Dai
- Liang Huakang
- Liang Shide
- Liao Wei-Ting
- Liao Zheng-Yin
- Lidbury Brett A.
- Lieb Klaus
- Liehr Thomas
- Liew Alan W.C.
- Lim Chinten J.
- Lim Renly
- Lim Yau Y.
- Lima Luiz R.A.
- Lin Jessica
- Lin Li
- Lin Michael Z.
- Lindsey Merry L.
- Line Paul-Dag
- Ling Tong
- Linn Sabrina N.
- Litfin Thomas
- Liu Dengcai
- Liu Enwu
- Liu Fang
- Liu Fengbin
- Liu Haiyan
- Liu Hongde
- Liu Siqi
- Liu Xiaodong
- Liu Yu-Peng
- Liu Yuchen
- Liu Zhonghua
- Liusuo Wang
- Lizer J.
- Lloyd Vett K.
- Lo Te-Wen
- Lobreglio Giambattista
- Locci Emanuela
- Loft Nikolai D.
- Loidl Josef
- Lopez-Escamez Jose A.
- Lopez-Ruiz Francisco J.
- Lorenzen Johan
- Lorkowski Stefan
- Lovell Nigel H.
- Lowies Cher
- Lu Cheng
- Lu Hua
- Lu Jin-Jian
- Lu Qiang
- Lu Wei
- Lu Yao
- Lu Zhiyong
- Luengo Gustavo S.
- Lum Fok M.
- Lund Bjarte A.
- Lundh Lars-Gunnar
- Luo Hang
- Lussier Alexandre A.
- Luu Andreas M.
- Lygirou Vasiliki
- Lynch Iseult
- Lysy Philippe A.
- Lyu Ran
- Ma Chuang
- Ma Lan
- Ma Liping
- Ma Lisong
- Ma Ruiyan
- Ma Wujun
- Mabb Angela
- Machhi Jatin
- Mack Heather G.
- Mackey David A.
- Macleod Angus
- Macwan Isaac
- Madala Hanumantha R.
- Madani Nima
- Mahato Ajay K.
- Mahavadi Poornima
- Mahdavi S.R.
- Maher Pamela
- Maher Toby
- Mai Zhi-Ming
- Maibach Edward W.
- Maity Sankar N.
- Majeed Haroon
- Major Rupert W.
- Makowiecki Kalina
- Malgrange Brigitte
- Mali Samira
- Mallinson Daniel J.
- Mallis Panagiotis
- Mamoulakis Charalampos
- Mangoni Arduino A.
- Manke Thomas
- Manstead Antony S.R.
- Mantalaris Athanasios
- Mao Wenzhi
- Marchbank Kevin J.
- Margelyte Ruta
- Maria Caracausi
- Marinello Francesco
- Markonis Y.
- Marsal Jan
- Marschalek Rolf
- Marschall H. U.
- Marsili Luca
- Mart\uedn Carmen S.
- Martin Adam
- Martin Francis L.
- Martinez-Raga Jose
- Martinez-Salas Encarnacion
- Martinez-Sobrido Luis
- Martis Elvis
- Marvin-Dowle Katie
- Marzocchi Ugo
- Mason Leanda D.
- Mather Diane E.
- Mathieu Daniel
- Matsui Yoichi
- Mavoa Suzanne
- Maza Elie
- McCrum Christopher
- McCutcheon James E.
- McGarrigle Christine A.
- McKay Gareth J.
- McMillan Brian
- McMillan Nigel
- McWilliams Lorna
- Meads Catherine
- Medina Loreta
- Megersa Moa
- Mendes Caetano S.M.
- Menichetti Julia
- Mercieca-Bebber Rebecca
- Meresh Edwin
- Merideth Ben
- Merino-Plaza Maria J.
- Merlaen Britt
- Merrick B. Alex
- Meseko Clement
- Messina Rossella
- Metzger Dennis W.
- Meule Adrian
- Meunier Frederic A.
- Michaelis Martin
- Micheau Olivier
- Middelveen Marianne
- Miele Adriana E.
- Mier Pablo
- Mihara Hisaaki
- Miller Jack J.
- Min Rogier
- Minde David-Paul M.
- Minges Alexander
- Mintz Eric M.
- Miotla Pawel
- Mishra Anand K.
- Mishra Eleanor
- Mishra Virendra R.
- Mitchell Kate M.
- Mizukami Takuo
- Moal Iain
- Moalic Yann
- Mohapatra D.P.
- Mohebbi Alireza
- Molari Massimiliano
- Molleman Lucas
- Mondal Saiful R.
- Montagutelli Xavier
- Monteiro Antonia
- Montes Matthieu
- Moore Matthew D.
- Moores Carly
- Moran John V.
- Morcillo Esteban
- Morozov Sergey Y.
- Morrice Nicola
- Mort Matthew
- Moskalensky Alexander E.
- Moss W.N.
- Mota Jorge
- Moultos Othonas A.
- Moyer Robert
- Mozaheb Zahra
- Muhammad Junaid
- Mukherjee Maheswari
- Murai Noriyuki
- Murphy Denis J.
- Murphy Susan K.
- Murray Shauna A.
- Musinguzi Conrad
- Muth Thilo
- Muyaya Ley
- Naganawa Shinji
- Nagler Katja
- Nakayama Kazuhiko
- Nammi Srinivas
- Nandakumar Kutty S.
- Nandhakumar Amar
- Nanou Afroditi
- Naqash Amreen
- Narayan Edward
- Nasios Grigorios
- Natoli Roman M.
- Navaratnarajah [NO FIRST NAME IN SCOPUS]
- Navarin Nicol\uf2
- Negera Edessa
- Neumann Philipp-Alexander
- Ng Grace
- Ng Sheryl H.X.
- Nguyen Frederique
- Nguyen Joe T.
- Nguyen Thi T.H.
- Ni Duan
- Nicol Christine
- Nicoletti Rosario
- Nida [NO FIRST NAME IN SCOPUS]
- Nie Jiyun
- Nie Yingjiu
- Niehof Monika
- Niemeyer Frank
- Nilsen Erlend B.
- Nilsson Henrik
- Nixon Brett
- Nobile Clarissa J.
- Nolan Fiona
- Nolet Philippe
- Nord\ue9n Rickard
- Nordberg Ana
- Norris Adam D.
- Notcovich Shirli
- Nowicki Jessica P.
- Nwaiwu Ogueri
- O\u27Mahony Margaret
- O\u27Toole Ronan
- Obeidat Monther
- Ogami Koichi
- Oh Deog-Hwan
- Ohgami Robert S.
- Ohlsson Sophie
- Ohst Barnabas
- Ohtomo Toshihiko
- Olatunbosun Oluremi
- Oldenmenger Wendy H.
- Ollivier Quinn R.
- Olofsson Per
- Olova Nelly
- Olszewski Pawel
- Olumayede Emmanuel
- Onzima Robert
- Orme Mark W.
- Ortiz Alberto
- Osses Dani\uebl F.
- Oster Henrik
- Ostrikov Kostya
- Otto Siegmar
- Ou Jianhong
- Outeiro Tiago F.
- Ouyang Songying
- Owais Mohammed
- Pace-Asciak Pia
- Paganoni Sabrina
- Page Andrew
- Pallebage-Gamarallage Menuka
- Palm Christoph
- Palma Jose-Alberto
- Pan Chih-Long
- Pan Zihang
- Panthee Suresh
- Panwar Ajay
- Paradies Yin
- Parchi Piero
- Park Caroline
- Park Charny
- Park Dong I.
- Park Seyoung
- Parsons Jerod R.
- Parsons Michael H.
- Parsons Nick
- Pascal Pigny
- Paterson Russell
- Patil Chandrashekhar D.
- Patterson Chris
- Paul Elisabeth
- Pearce Simon P.
- Pearson James A.
- Peckham Michelle
- Pedemonte Nicoletta
- Pedro Sansoa A.
- Peifer Mark
- Pelkonen Tuula
- Pelleri Maria C.
- Pellizzon Michael A.
- Penagos-Tabaree Felipe
- Peng Xiangda
- Peng Yousong
- Perco Paul
- Pereira Joana L.
- Peres Marco A.
- Perry Samuel R.
- Peter Jessica
- Peterson Brent M.
- Petrelli M.
- Pezzuolo Andrea
- Pheko Mpho
- Pianosi Paolo T.
- Pichugin Alexander
- Pinto Carlos J.C.
- Pinto Ines M.
- Pinto Karina A.
- Pinzi Valentina
- Piotrowski Marcin
- Piovesan Allison
- Plantinga Arnoud
- Plevris John N.
- Pluess Michael
- Podolsky Illya M.
- Pollesello Piero
- Polz Martin
- Ponti Giovanna
- Popoola Segun I.
- Porcelli Piero
- Portilla Maribel
- Portillo M.C.
- Pourret Olivier
- Pozdnyakov Ilya
- Prajapati Anilkumar S.
- Pranata Raymond
- Prescott Julie
- Pridans Clare
- Prieto Daniel
- Prince Martin
- Pritchard Antonia L.
- Psaroulaki Anna
- Pujala Ravi K.
- Pulia Michael
- Pulido-Arjona Leonardo
- Pullan Wayne
- Pusch Stefan
- Qi Dongchen
- Qi Peng-Fei
- Qi Xingshun
- Qian Siyu
- Qin Lei
- Quinn Gwendolyn P.
- Quinn Terence J.
- Rafe Ali
- Rafiq Muhammad
- Raghava Gajendra P.S.
- Rahimi Farid
- Rahman Proton
- Rahman Shaifur
- Rai Nayanjot K.
- Raikou Vaia D.
- Raman Ayush
- Ramula Satu
- Ranft Andreas
- Raote Ishier
- Rappsilber Juri
- Rassaf Tienush
- Raucher-Ch\ue9n\ue9 [NO FIRST NAME IN SCOPUS]
- Rawski Rafal
- Ray Asit
- Raza Ali
- Razak Lubna A.
- Rebl Henrike
- Reddan Tristan
- Refai Osama
- Refardt Julie
- Regan Tim
- Rehfeldt Florian
- Reiling Jan H.
- Remacle Claire
- Reschke Cristina R.
- Rezaei Mohsen
- Rhodes Johanna
- Ricciardi Walter
- Richa Tambi
- Richardson Mark F.
- Riddick Eric W.
- Riess Olaf
- Ritter Uwe
- Riva Giuseppe
- Roach Neil W.
- Roberts David D.
- Roberts Nicola J.
- Robinson K.R.
- Robles Guillermo
- Rodrigues Tiago
- Rodriguez Cesar
- Roislien Jo
- Roobol Monique J.
- Ross Kehinde
- Ross Stephanie A.
- Rossoni Luca
- Rotge Jean-Yves
- Rouet Romain
- Rovas Alexandros
- Rowe Alexandra
- Rowe Anna D.
- Rudolf Kevin
- Ruepp Andreas
- Rusch Peter
- Rust Petra
- S\uf6relius Karl
- Saad Sonia
- Sabnis Sandeep C.
- Sack George H.
- Sacks Frank M.
- Sadoine Margaux L.
- Safaei Soroush
- Saggar Manish
- Saito Yu
- Salama Mohamed F.
- Saleh Sherif
- Sallmon Hannes
- Sampson Christopher
- Santos Manuela
- Saudemont Aurore
- Sava Gianni
- Schmidt Axel
- Schmutz Axel
- Schneeberger Pierre H.H.
- Schrading Simone
- Schramm Alexander
- Schreiber Martin
- Schuele Birgitt
- Schuler Sidney
- Schulte Leon N.
- Schuon Robert A.
- Schurr Roey
- Schwotzer Daniela
- Schymkowitz Joost
- Sczyrba Alexander
- Searles Stephen
- Sebastian Agata
- Seib Kate L.
- Selinski Jennifer
- Seltmann Stefanie
- Senghore Thomas
- Seow Esmond
- Sepanski Robert
- Sergeant Kjell
- Sha Feng
- Shabalin Ivan G.
- Shahid Shaouli
- Shalchyan Vahid
- Shalev Nir
- Shang Jin-Long
- Sharma Neeraj
- Sharma Saurab
- Sheehan Barry
- Shen Jun
- Shi Chunhu
- Shi Han-Ping
- Shimada Tomohiro
- Shin Jeon-Soo
- Shirvalkar Prasad
- Shiryayev Oleg
- Shohayeb Belal
- Shortt Colette
- Siebers Robert
- Sillanp\ue4\ue4 Elina
- Silveyra Patricia
- Singer Josef
- Singh Jugpreet
- Singh Mandeep
- Singh Manisha
- Skinner Debra
- Small Ian
- Smeets Paul A.M.
- Smith Simon S.
- Smith Taylor
- Smout Michael J.
- So Po-Wah
- Soares Ant\uf3nio
- Solano Francisco
- Solomon-Moore Emma
- Sommerlad Andrew
- Sonenshine Daniel E.
- Song Chunjiao
- Song Haijun
- Song Jiangning
- Song Lijuan
- Soraggi Samuele
- Sorzano Carlos O.
- Southall Tony
- Speakman John R.
- Spearman Paul
- Srinivasan Mandyam V.
- Srivastava Kshitij
- Srivastava Rupesh K.
- Stabile Laura P.
- Staege Martin S.
- Stanley Ryan
- Stasiak A.
- Steadman Kathryn J.
- Steckhan Nico
- Stein Nils
- Stella Alessandro
- Stephens Andrew W.
- Stevanovic Dejan
- Stewart Christopher J.
- Stewart Douglas I.
- Stine Keith
- Storlazzi Curt
- Stoynova Nataliya V.
- Strehlow Jan
- Strobl Frederic
- Strzalka Wojciech
- Suarez Oscar M.
- Subhash Santhilal
- Subissi Lorenzo
- Subramaniapillai Mehala
- Sukocheva Olga
- Sultana Taranum
- Sumant Anirudha V.
- Summers Mathew J.
- Sun Gang
- Sun Jim
- Sun Xianbao
- Sundar Raghav
- Supriyanto Irwan
- Surve Chinmay R.
- Suzuki Tomo
- Swali Ritu
- Sydes Matthew
- Syme Caitlin
- Szabo Attila
- Szymanski Wiktor
- Tacon Paul
- Taherzadeh Ghazaleh
- Tahir Nur D.M.
- Tai Chan N.P.
- Takeuchi Hisashi
- Tamaian Radu
- Tan Aik-Choon
- Tan Cher M.
- Tan Ene-Choo
- Tan Kok H.
- Tanadini-Lang S.
- Tanaka Kozo
- Tang Fei
- Tang Haixu
- Tang Jun
- Tang Young
- Tanino Y.
- Tantawy Marwa
- Tao Wanyin
- Targett-Adams Paul
- Tayebi Mourad
- Tayyem Reema
- Tebbe Christoph C.
- Telfer Evelyn E.
- Tellechea Juan I.
- Tempel Wolfram
- Tennakoon Sumudu
- Teodorczyk-Injeyan Julita A.
- Terrier Olivier
- Teseo Serafino
- Testa Jean
- Testoni Ines
- Theron G.
- Thijs Gert
- Thomas Lisa-Marie
- Thorne Sally
- Thrift Amanda G.
- Tian Chang F.
- Tian Yu-Shi
- Tian Zhiqi
- Tiffon Celine
- Tingting Qian
- Tinnefeld Philip
- Tjahjono Daryono H.
- Toelzer Christine
- Tofani Marco
- Tolle Fabrice
- Tomov Nikola
- Tong Xin
- Torga Gonzalo
- Toth Ervin
- Tovar Miguel
- Tr\uf6der Simon E.
- Tran Linh
- Tressoldi Patrizio
- Tripathi Sushil
- Tsapas Apostolos
- Tsirigotis Konstantinos
- Tuladhar Anil M.
- Turak Ayse
- Tuttle Lisa M.
- Tuttle Neil
- Tzotzos George
- Uchendu Florence
- Udo Edet E.
- Uhle Florian
- Ukubuiwe Azubuike C.
- Ung Carolina O.L.
- Utsumi Toshiaki
- Uversky Vladimir N.
- Vaidyanathan Subramanian
- Vaillant Michel
- Valenti Anna
- Valgepea Kaspar
- Valsesia Armand
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- van den Bos Wouter
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- van Nieuwerburgh Filip
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- van Ruitenbeek Jan
- Vandenbroucke Roosmarijn E.
- Vanneste Sven
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- Veiga Feliciano H.
- Vendrell Marc
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- Verloh Niklas
- Verlot Pierre
- Vesk Peter A.
- Veys Ralf
- Vickers Paul
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- Vidal Arnau
- Villemur Richard
- Villet Martin H.
- Vindin Howard
- Vitriol Veronica
- Viveiros Miguel
- Vohl Marie-Claude
- Voolstra Christian R.
- Vorholt Julia A.
- Voskarides Konstantinos
- Voutchkova Denitza D.
- Vuillemin Anne
- Wakelin Steven
- Waldron Levi
- Walker Mirella
- Walsh Laurence J.
- Wang Amanda Y.
- Wang Fang
- Wang Fuan
- Wang Horng-Dar
- Wang Jinhui
- Wang Jiucun
- Wang Jun
- Wang Qing
- Wang Teng
- Wang Xiaomin
- Wang Yun
- Wang Zhenxing
- Watanabe Yoichi
- Watari Ricky
- Waugh Jason
- Webb S.A.
- Webster Rebecca
- Webster Ruth
- Wei Junnian
- Wei Pan
- Weigert Andreas
- Weinstock Christof
- Welter Danielle
- Wen Jet-Chau
- Werner Gijsbert D.A.
- Werten Sebastiaan
- Westermair Anna L.
- Wham Carol
- White Ethan P.
- Wibowo David
- Widera Darius
- Wiener Jan
- Wilharm Gottfried
- Wilkinson Simon
- Williams Brendan A.
- Williams Richard
- Willmann Raffaella
- Wilson Alex
- Wilson Coralie
- Wingenbach Tanja S.H.
- Winslade Matthew
- Wirth Brunhilde
- Wojan Timothy R.
- Woldesemayat Adugna A.
- Wolff Mathieu
- Wong Alvin
- Wong Bryan M.
- Workman Alan D.
- Wu Dalei
- Wu Tzu-Wei
- Wu Yi-Rui
- Wuerbel Hanno
- Wyart [NO FIRST NAME IN SCOPUS]
- Xavier Rose M.
- Xia Wenfeng
- Xiang Tingxiu
- Xiao Han
- Xiao Shumin
- Xiao Xiangshu
- Xie Li-Xin
- Xiong Peng
- Xu Beisi
- Xu Dong
- Xu Haotian
- Xu J.W.
- Xu Jialin
- Xu Jianping
- Xu Juan
- Xu Jun
- Xu Shicai
- Xu Shilin
- Xu Taosheng
- Xu Ziyue
- Xue Bin
- Xue Yu
- Yadollahpour Ali
- Yalcin Suayib
- Yamato Masayuki
- Yan Hong
- Yang Chongjun
- Yang Dongdong
- Yang En-Cheng
- Yang Hui
- Yang Long
- Yang Mingjun
- Yang Shiqi
- Yang Sunny Y.
- Yang Wei
- Yang Yongliang
- Yankilevich Patricio
- Yao Ruifeng
- Yao Wen
- Yassine Abdul-Amir
- Ye Yuzhen
- Ye Zhi-Qiang
- Yeung Andy W.K.
- Yin Cong-Cong
- Yin Qinan
- Yli-Kauhaluoma Jari
- Yoneyama Hiroshi
- Yoon Jihoon G.
- You Yuyi
- Yousefzadeh Abbas
- Yu Chenglong
- Yu Ying
- Yu Yongbo
- Yuan Christina M.
- Yuan Guo-Cheng
- Yuh Chiou-Hwa
- Zabetakis Ioannis
- Zaccolo Manuela
- Zaitsu Masayoshi
- Zare Asma
- Zaritsky Arno
- Zaucha Jan
- Zeineb Zian
- Zeng Chen
- Zeng Erliang
- Zeng Zhen
- Zevnik Branko
- Zhan Jian
- Zhan Xiao-Yong
- Zhang Chengrong
- Zhang Chi
- Zhang Chongxing
- Zhang Gong
- Zhang Haowen
- Zhang Jilei
- Zhang Junpeng
- Zhang Kai
- Zhang Li
- Zhang Linxing
- Zhang Rongqiang
- Zhang Tongchuan
- Zhang Tuo
- Zhang Wei
- Zhang Weijia
- Zhang Xianglilan
- Zhang Xiaolei
- Zhang Yao
- Zhang Yi
- Zhang Yingkai
- Zhang Yusen
- Zhang Zhe
- Zhang Zhiyong
- Zhang Zhong-Yin
- Zhang Zhongheng
- Zhao Guoyan
- Zhao Haochen
- Zhao Jing
- Zhao Xin
- Zhao Yuan
- Zheng Shan
- Zhou Bailing
- Zhou Jianyu
- Zhou Kai
- Zhou Min
- Zhou Xiaofan
- Zhou Xiaoyan
- Zhou Yaoqi
- Zhu Dongjie
- Zhu Shu
- Zhu Zhenxing
- Ziegler Andreas
- Zinke Katharina
- Zuberbier Torsten
- Zuckerman Hannah
- Publication venue
- Publication date
- 01/01/2019
- Field of study
Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical research.Peer reviewe
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples
- Author
- A Gordon Robertson
- Abdullah Kahraman
- Abel Gonzalez-Perez
- Adam A Margolin
- Adam Abeshouse
- Adam Grundhoff
- Adam J Struck
- Adam J Struck
- Adam J Wright
- Adam Lambert
- Adam P Butler
- Adam P Butler
- Adel El-Naggar
- Adnan M Nagrial
- Adrian Ally
- Adrian Baez-Ortega
- Adrian Thorogood
- Adriana Salcedo
- Adrienne M Flanagan
- Ake Borg
- Akihiro Fujimoto
- Akihiro Suzuki
- Akinyemi I Ojesina
- Alain Viari
- Alan J Robertson
- Alan P Hoyle
- Alan Thompson
- Alasdair Stenhouse
- Alastair M Thompson
- Aldo Scarpa
- Alessandro Pastore
- Alex Buchanan
- Alex Buchanan
- Alexander Claviez
- Alexander J Lazar
- Alexander Martinez-Fundichely
- Alfonso Muñoz
- Alfonso Valencia
- Aliaksei Z Holik
- Alice Meng
- Alicia L Bruzos
- Allison Creason
- Allison P Heath
- Alvin Wei Tian Ng
- Alvis Brazma
- Amaro Taylor-Weiner
- Amber L Johns
- Amie Radenbaugh
- Amit G Deshwar
- Ana Dueso-Barroso
- Ana Mijalkovic Mijalkovic-Lazic
- Ana Milovanovic
- Ana Milovanovic
- Andre Kahles
- Andrea Haake
- Andrea Holbrook
- Andrea L Richardson
- Andrea Mafficini
- Andrea Ruzzenente
- Andreas Behren
- Andreas Rosenwald
- Andreia V Pinho
- Andrew Berchuck
- Andrew D Cherniack
- Andrew J Dunford
- Andrew J Mungall
- Andrew J Spillane
- Andrew Menzies
- Andrew Menzies
- Andrew P Barbour
- Andrew Tutt
- Andrew V Biankin
- Andrey Korshunov
- Andrés Lanzós
- Andy Cafferkey
- Andy G Lynch
- Angela Chou
- Angela N Brooks
- Angela Tam
- Angelica Ochoa
- Angelika N Christ
- Angelo P Dei Tos
- Anieta M Sieuwerts
- Anil K Sood
- Anita Langerød
- Anja Füllgrabe
- Anke K Bergmann
- Ann-Marie Patch
- Anna deFazio
- Anna Ehinger
- Anna Fitzgerald
- Anne Hamilton
- Anne Vincent-Salomon
- Anne Y Warren
- Anne-Lise Børresen-Dale
- Annegien Broeks
- Anthony DiBiase
- Anthony J Gill
- Anthony Ng
- Anthony R Green
- Antonia L Pritchard
- Antonio Pea
- Antonios Koures
- Aparna Prasad
- Apurva M Hegde
- Aquila Fatima
- Arcadi Navarro
- Arie B Brinkman
- Arif O Harmanci
- Arindam Maitra
- Armando Lopez-Guillermo
- Arndt Borkhardt
- Arnoud Boot
- Asger Hobolth
- Ashley Williams
- Ashton A Connor
- Atul J Butte
- Aurélien Chateigner
- Austin J Hepperla
- Axel Aretz
- Aya Sasaki-Oku
- Ayellet V Segre
- B F Francis Ouellette
- Bailey Matthew H
- Barbara Hutter
- Barbara Hutter
- Barbara Kremeyer
- Bartha M Knoppers
- Beifang Niu
- Beifang Niu
- Beifang Niu
- Benedikt Brors
- Benita Kiat Tee Tan
- Benjamin J Raphael
- Benjamin P Berman
- Benjamin Raeder
- Bernardo Rodriguez-Martin
- Bernhard Radlwimmer
- Bernice H Wong
- Beth Karlan
- Bin Tean Teh
- Bin Zhu
- Birgit Burkhardt
- Bishoy M Faltas
- Bodil Bjerkehagen
- Bogdan Czerniak
- Boris Winterhoff
- Borislav C Rusev
- Bradly G Wouters
- Brandi N Davis-Dusenbery
- Brian Craft
- Brian D O'Connor
- Brian Patrick O'Neill
- Brice Aminou
- Calvin Wing Yiu Chan
- Cameron M Soulette
- Carl Herrmann
- Carl Morrison
- Carlo Gambacorti-Passerini
- Carlos Caldas
- Carlos D Bustamante
- Carlos López-Otín
- Carlota Rubio-Perez
- Carmen Gomez
- Carolien H M van Deurzen
- Carolyn M Hutter
- Carolyn M Hutter
- Carrie Cibulskis
- Caterina Vicentini
- Catherine A Shang
- Catherine D Moser
- Catherine J Kennedy
- Catrina C Fronick
- Chad J Creighton
- Chandra Sekhar Pedamallu
- Chang Li
- Charles David Imbusch
- Charles M Perou
- Charles Saller
- Charles Short
- Charlie E Massie
- Chawalit Pairojkul
- Chen Hong
- Chen Ye
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- Chin-Lee Wu
- Chip Stewart
- Chip Stewart
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- Christopher K Wong
- Christopher M Lalansingh
- Christopher M Lalansingh
- Christopher Ogden
- Christopher S Foster
- Christopher Umbricht
- Christopher W Toon
- Christos Sotiriou
- Cindy Bell
- Cinzia Cantù
- Ciyue Shen
- Claes Wadelius
- Clare Verrill
- Clarissa Gerhauser
- Claudia Calabrese
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- Claudiu Farcas
- Clemency Jolly
- Colin A Purdie
- Colin A Semple
- Colin C Collins
- Colin S Cooper
- Conrad R Leonard
- Constance H Li
- Corbin D Jones
- Craig Shriver
- Cristina López
- Cyriac Kandoth
- Cyril Fisher
- D Neil Hayes
- Dai-Ying Wu
- Daiming Fan
- Daisuke Komura
- Dale W Garsed
- Daniel A Leongamornlert
- Daniel Baumhoer
- Daniel Hübschmann
- Daniel J Turner
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- Daniel M Berney
- Daniel Rosebrock
- Daniel S Brewer
- Daniela S Gerhard
- Danielle Pasternack
- Darell Bigner
- Dariush Etemadmoghadam
- Darlene Lee
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- Dave Larson
- David A Wheeler
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- Dennis Wigle
- Derek W Wright
- Dianne E Chadwick
- Dido Lenze
- Dieter Kube
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- Dilip D Giri
- Dimitri Livitz
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- Ding
- Dirk Schadendorf
- Dmitry A Gordenin
- Dominik Glodzik
- Don Chalmers
- Dong Guanlan
- Dongbing Liu
- Donghoon Lee
- Donghui Tan
- Donna M Muzny
- Dorthe Grabau
- Douglas A Levine
- Douglas F Easton
- Douglas Voet
- Duncan Beardsmore
- Dursi Lewis Jonathan
- Edward W Rowe
- Eigo Shimizu
- Ekta Khurana
- Elaine R Mardis
- Electron Kebebew
- Elena Piñeiro-Yáñez
- Elena Provenzano
- Elias Campo
- Elisabet Barrera
- Elisabetta Sereni
- Elizabeth A Musgrove
- Elizabeth L Appelbaum
- Elizabeth L Christie
- Elli Papaemmanuil
- Ellrott Kyle
- Emilie Lalonde
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- Eva G Alvarez
- Eva Hellstrom-Lindberg
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- F Germán Rodríguez-González
- Fabien C Lamaze
- Fabien Calvo
- Fabio C P Navarro
- Faiyaz Notta
- Fan Yang
- Fan Zhang
- Faraz Hach
- Faraz Hach
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- Felicity Newell
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- Fernanda Amary
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- Florian Markowetz
- Fouad Yousif
- Francesc Muyas
- Francesco Favero
- Francisco M De La Vega
- Francisco Sanchez-Vega
- Fraser R Duthie
- Fred Sweep
- Freddie C Hamdy
- Fruzsina Molnár-Gábor
- Fumie Hosoda
- G Petur Nielsen
- G Steven Bova
- Gad Getz
- Gad Getz
- Gad Getz
- Gaetan MacGrogan
- Gaetano Finocchiaro
- Gary D Bader
- Gavin Ha
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- Genta Nagae
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- George L Mihaiescu
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- Georgina V Long
- Gerd Nettekoven
- German M Demidov
- German Ott
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- Gerstein Mark B
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- Getz Gad
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- Giampaolo Tortora
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- Gilles Thomas
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- Giuseppe Malleo
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- Grace Tiao
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- Grant Sanders
- Gu Kong
- Guanming Wu
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- Guido Sauter
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- Gulietta M Pupo
- Gun Ho Jang
- Gunes Gundem
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- Gurnit Atwal
- Hailei Zhang
- Haiyan Irene Li
- Han Liang
- Hana Susak
- Hans Binder
- Hans Lehrach
- Hans-Jörg Warnatz
- Hardeep K Nahal-Bose
- Hark Kyun Kim
- HarshaVardhan Doddapaneni
- Hartmut Juhl
- Harvey Pass
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- Hayley J Luxton
- Hazel Burke
- Heather K Schmidt
- Heather Thorne
- Hee Jin Lee
- Heidi J Sofia
- Heidi Sofia
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- Helena Kilpinen
- Helene Kretzmer
- Heng Xiong
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- Henrik Hornshøj
- Henry Lee-Six
- Hideki Ohdan
- Hidenori Ojima
- Hidewaki Nakagawa
- Hikmat Al-Ahmadie
- Hilda A Pickett
- Hirofumi Rokutan
- Hirokazu Taniguchi
- Hiroki Yamaue
- Hiroko Tanaka
- Hiromi Nakamura
- Hiroshi Aikata
- Hiroto Katoh
- Hiroyuki Aburatani
- Hitoshi Katai
- Hitoshi Nakagama
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- Holmfridur Hilmarsdottir
- Hong Su
- Hong Xue
- Hong Xue
- Hongtu Zhu
- Hongwei Zhang
- Hongxin Zhang
- Hsiao-Wei Chen
- Huanming Yang
- Hugh Barr
- Hui Shen
- Husen M Umer
- Huy Q Dinh
- Hyung-Lae Kim
- Hyung-Lae Kim
- Hyung-Yong Kim
- Hyunghwan Kim
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- Ian Welch
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- Ignaty Leshchiner
- Ignaty Leshchiner
- Ignaty Leshchiner
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- Ilse Rooman
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- Iman Sarrafi
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- Irinel Popescu
- Iris Pauporté
- Iris Selander
- Isabelle Treilleux
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- Ivan Borozan
- Ivana Cataldo
- Ivica Letunic
- Ivica Letunic
- Ivo Buchhalter
- Ivo Buchhalter
- Ivo G Gut
- Ivo G Gut
- Ivon Harliwong
- Izar Villasante
- Iñigo Martincorena
- J Lynn Fink
- J Robert O'Neill
- J Todd Auman
- Jaclyn Smith
- Jacqueline Boultwood
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- Jaegil Kim
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- Jakob Skou Pedersen
- Jakob Skou Pedersen
- James E Haber
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- James Gossage
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- Jane E Brock
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- Jared T Simpson
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- Karolina Czajka
- Karsten Rippe
- Katalin Karaszi
- Katarzyna O Sikora
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- Kathleen H Burns
- Kathleen Marchal
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- Katia Nones
- Kazuaki Chayama
- Kazuhiro Maejima
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- Keiran M Raine
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- Kristian Cibulskis
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- Kyle Ellrott
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- Leslie Cope
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- Liliana Greger
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- Lincoln D Stein
- Linda Mileshkin
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- Lisa Lype
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- Lucinda A Fulton
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- Luke Marsden
- Maciej Wiznerowicz
- Malcolm Brock
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- Malene Juul
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- Mamoru Kato
- Manasa Ramakrishna
- Manaswi Gupta
- Manolis Kellis
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- Marat D Kazanov
- Marc D Perry
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- Marc J van de Vijver
- Marc Zapatka
- Marcel Kool
- Marcel Smid
- Marcin Imielinski
- Marco A Marra
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- Vincenzo Corbo
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- W Kimryn Rathmell
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- Wan Choi
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- Wei Jiao
- Wendl Michael C
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- Winghing Wong
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- Xiao Xiao
- Xiaobo Li
- Xiaoping Su
- Xiaotong Li
- Xiaotong Yao
- Xing Hua
- Xingmin Liu
- Xinyue Li
- Xiuqing Zhang
- Xiuqing Zheng
- Xose S Puente
- Xuan Le
- Xuanping Zhang
- Xuemei Luo
- Xueqing Zou
- Yan Shi
- Yan Zhang
- Yang Wu
- Yang Yang
- Yann Joly
- Yanxun Xu
- Yao He
- Yasin Senbabaoglu
- Yassen Assenov
- Yasser Riazalhosseini
- Yasuhito Arai
- Yasushi Rino
- Yasushi Totoki
- Yeng Ang
- Yi Huang
- Yi Huang
- Yifei Men
- Yiling Lu
- Yilong Li
- Yingyan Yu
- Yiwen Chen
- Yogesh Kumar
- Yogesh Kumar
- Yoke-Eng Chiew
- Yong Hou
- Yong Zhou
- Yong-Jie Lu
- Yongzhan Nie
- Yosef E Maruvka
- Yosef E Maruvka
- Yoshiiku Kawakami
- Young Seok Ju
- Youngchoon Woo
- Youngil Koh
- Youngwook Kim
- Youyong Lu
- Yu Fan
- Yu Fan
- Yu Fan
- Yu-Jia Shiah
- Yuan Ji
- Yuan Yuan
- Yuichi Shiraishi
- Yulia Newton
- Yulia Rubanova
- Yumeng Wang
- Yupeng Cun
- Yussanne Ma
- Zachary Heins
- Zechen Chong
- Zechen Chong
- Zemin Zhang
- Zhaohong Chen
- Zhenggang Wu
- Zhenggang Wu
- Zhining Wang
- Zhongming Zhao
- Ziao Lin
- Zsofia Kote-Jarai
- Ólafur Andri Stefánsson
- Øystein Garred
- Publication venue
- Nature Communications
- Publication date
- 01/01/2020
- Field of study
Funder: NCI U24CA211006Abstract: The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome sequencing (WES) and whole genome sequencing (WGS), respectively. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2,658 cancers across 38 tumour types, we compare WES and WGS side-by-side from 746 TCGA samples, finding that ~80% of mutations overlap in covered exonic regions. We estimate that low variant allele fraction (VAF < 15%) and clonal heterogeneity contribute up to 68% of private WGS mutations and 71% of private WES mutations. We observe that ~30% of private WGS mutations trace to mutations identified by a single variant caller in WES consensus efforts. WGS captures both ~50% more variation in exonic regions and un-observed mutations in loci with variable GC-content. Together, our analysis highlights technological divergences between two reproducible somatic variant detection efforts
Microglia and major depression: not yet a clear picture
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/04/2018
- Field of study
In memoriam, Roy Weller (1938-2022).
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2022
- Field of study
- …