20 research outputs found

    Long-Term Exercise Training Attenuates Age-Related Diastolic Dysfunction: Association of Myocardial Collagen Cross-Linking

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    The incidence of diastolic heart failure increases dramatically with age. We investigated the impact of long-term exercise training on age-related diastolic dysfunction. Old (25-month-old) male Fischer 344 rats were studied after 12 weeks of treadmill exercise training or sedentary cage life (N=7, in each group). We determined cardiac performance using a pressure-volume conductance catheter and magnetic resonance imaging. Collagen volume fraction (CVF) and myocardial collagen solubility by pepsin as an index of advanced glycation end products (AGEs) cross-linked collagen were measured. The maximal slope of systolic pressure increment (+dP/dt) and the slope of end-systolic pressure-volume relation were higher, and end diastolic volume (EDV), ΔEDV (the percentage of the EDV increment-to-baseline EDV) and the slope of end-diastolic pressure-volume relation were lower in training group. The maximal slope of diastolic pressure decrement (-dP/dt) and time constant of LV pressure decay (τ) had no difference. AGEs cross-linked collagen, not CVF was reduced by exercise training. Long-term exercise training appears to attenuate age-related deterioration in cardiac systolic function and myocardial stiffness and could be reduce in pathologic AGEs cross-linked collagen in myocardium

    Molecular imprinting science and technology: a survey of the literature for the years 2004-2011

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    Study of production optimization and effect of hydroxyl gas on a CI engine performance and emission fueled with biodiesel blends

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    Depletion and environmental impacts of the fossil fuel are the major concerns to think about the alternative energy sources to reduce the load on petroleum fuel. Researchers worldwide are working years to improve the biodiesel fuel economy and emission characteristic. At the same time, they are working on fuel development so that can be used in the IC engine without significant modification in vehicle design. Among different alternative fuels biodiesel as well as hydroxyl gas (HHO, also known as Oxyhydrogen gas) are renewable, recyclable and non-polluting fuel. In this study, HHO gas has been introduced with ordinary diesel (OD) and 20% (v/v) palm biodiesel blended with OD (PB20) for evaluating the engine performance and emission characteristics. Optimum yield of HHO was found using single anode and two cathodes from a solution containing 1% KOH and 100 ml of water producing 2150 cc of HHO gas when electrolysis was carried out for 15 min. Using the HHO generator, about 2% more power and 5% less consumption was observed for biodiesel blended fuel in a single cylinder CI engine at full load variable speed operating conditions. Besides, on an average 20% and 10% reduction of CO and HC emission were observed respectively

    Properties and use of Moringa oleifera biodiesel and diesel fuel blends in a multi-cylinder diesel engine

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    Researchers have recently attempted to discover alternative energy sources that are accessible, technically viable, economically feasible, and environmentally acceptable. This study aims to evaluate the physico-chemical properties of Moringa oleifera biodiesel and its 10% and 20% by-volume blends (B10 and B20) in comparison with diesel fuel (B0). The performance and emission of M. oleifera biodiesel and its blends in a multi-cylinder diesel engine were determined at various speeds and full load conditions. The properties of M. oleifera biodiesel and its blends complied with ASTM D6751 standards. Over the entire range of speeds, B10 and B20 fuels reduced brake power and increased brake specific fuel consumption compared with B0. In engine emissions, B10 and B20 fuels reduced carbon monoxide emission by 10.60% and 22.93% as well as hydrocarbon emission by 9.21% and 23.68%, but slightly increased nitric oxide emission by 8.46% and 18.56%, respectively, compared with B0. Therefore, M. oleifera is a potential feedstock for biodiesel production, and its blends B10 and B20 can be used as diesel fuel substitutes

    Evaluation of combustion, performance, and emissions of optimum palm-coconut blend in turbocharged and non-turbocharged conditions of a diesel engine

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    Fossil fuel depletion, global warming with rapid changes in climate, and increases in oil prices have motivated scientists to search for alternative fuel. Biodiesel can be an effective solution despite some limitations, such as poor fuel properties and engine performance. From this perspective, experiments were carried out to improve fuel properties and engine performance by using a binary blend of palm and coconut biodiesel at an optimized ratio. MATLAB optimization tool was used to determine this blend ratio. A new biodiesel was developed and represented by PC (optimum blend of palm and coconut biodiesel). Engine performance and emission were tested under a full load at variable speed condition by using a 20% blend of each biodiesel with petroleum diesel, and the results were compared with petroleum diesel under both turbocharged and non-turbocharged conditions. PC20 (blend of 20% PC biodiesel and 80% petroleum diesel) showed the highest engine power with lower brake-specific fuel consumption than the other tested fuels in the presence of a turbocharger. The emissions of PC20 were lower than those of all other tested fuels. The experimental analysis reveals that PC showed superior performance and emission over palm biodiesel blend

    Properties and use of Moringa oleifera biodiesel and diesel fuel blends in a multi-cylinder diesel engine

    No full text
    Researchers have recently attempted to discover alternative energy sources that are accessible, technically viable, economically feasible, and environmentally acceptable. This study aims to evaluate the physico-chemical properties of Moringa oleifera biodiesel and its 10% and 20% by-volume blends (B10 and B20) in comparison with diesel fuel (B0). The performance and emission of M. oleifera biodiesel and its blends in a multi-cylinder diesel engine were determined at various speeds and full load conditions. The properties of M. oleifera biodiesel and its blends complied with ASTM D6751 standards. Over the entire range of speeds, B10 and B20 fuels reduced brake power and increased brake specific fuel consumption compared with B0. In engine emissions, B10 and B20 fuels reduced carbon monoxide emission by 10.60% and 22.93% as well as hydrocarbon emission by 9.21% and 23.68%, but slightly increased nitric oxide emission by 8.46% and 18.56%, respectively, compared with B0. Therefore, M. oleifera is a potential feedstock for biodiesel production, and its blends B10 and B20 can be used as diesel fuel substitutes
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