14 research outputs found
Human matrix metalloproteinases: An ubiquitarian class of enzymes involved in several pathological processes
- Author
- Adachi
- Adachi
- Agarwal
- Agarwal
- Agrawal
- Ahmad
- Ahmed
- Ahn
- Ahokas
- Ahokas
- Aihara
- Airola
- Akhtar
- Ala-aho
- Ala-Aho
- Alam
- Albrecht
- Amberger
- Annabi
- Anthony
- Apte
- Araujo
- Ardi
- Aresu
- Arlt
- Arthur
- Asahina
- Atkinson
- Atkinson
- Atkinson
- Aureli
- Avolio
- Ayoub
- Azar
- Babusyte
- Baciu
- Badiga
- Bafetti
- Baines
- Balbin
- Balbin
- Balbin
- Banda
- Bar-Or
- Baramova
- Barascuk
- Barksby
- Barmina
- Barnes
- Barret
- Barrowman
- Basset
- Basset
- Bassi
- Bau
- Bayes-Genis
- Beck
- Becker
- Belaaouaj
- Belaaouaj
- Beliveau
- Beliën
- Belkin
- Bendardaf
- Bendrik
- Benesova
- Benesova
- Bergers
- Bergmann
- Bernal
- Bernal
- Bernstein
- Berry
- Betsuyaku
- Bhaskar
- Bhaskaran
- Billinghurst
- Bilousova
- Binder
- Binker
- Bisson
- Bister
- Bister
- Biswas
- Björklund
- Bjørn
- Bland
- Blavier
- Blobel
- Blumenthal
- Bode
- Bode
- Boldt
- Bolignano
- Bolon
- Bonacci
- Bord
- Borges
- Borkakoti
- Borrell-Pages
- Boulay
- Bourboulia
- Bourguignon
- Bozzi
- Bradbury
- Bralet
- Brauer
- Brew
- Briknarova
- Brinckerhoff
- Brinckerhoff
- Brinckerhoff
- Broide
- Brooks
- Brown
- Buhler
- Buhmeida
- Bujak
- Burke
- Burrage
- Butoi Dragomir
- Bylander
- Byun
- Caceres
- Cai
- Campbell
- Cao
- Cao
- Capell
- Capell
- Carl-McGrath
- Carrel
- Carrell
- Carty
- Cataldo
- Cataldo
- Cauwe
- Cauwe
- Cauwe
- Cazorla
- Cha
- Chabottaux
- Chabry
- Chaffer
- Chambers
- Chan
- Chandler
- Chang
- Chang
- Chang
- Chantrain
- Chapman
- Charbonneau
- Chaudhary
- Checler
- Chen
- Chen
- Chen
- Chen
- Chen
- Chen
- Chen
- Cheng
- Chetty
- Chetty
- Chiao
- Chiara Ciaccio
- Chiba
- Chin
- Cho
- Cho
- Choi
- Choke
- Chung
- Chung
- Churg
- Churg
- Churg
- Churg
- Clements
- Clements
- Cleutjens
- Colige
- Collier
- Colotti
- Comabella
- Conant
- Conover
- Conover
- Consuegra-Sanchez
- Consuegra-Sanchez
- Copin
- Cosgrove
- Coulson-Thomas
- Coussens
- Coussens
- Coussens
- Culpitt
- Curci
- Cyr
- Daniele
- Danielsen
- Daull
- Davidson
- Davidson
- Davies
- Davis
- De Coignac
- Deb
- Decock
- Deguchi
- Dehan
- Del Zoppo
- Delassus
- Demedts
- Denecke
- Deng
- Denny
- Deryugina
- Deryugina
- Deryugina
- Deshmukh
- Devarajan
- Di Bella
- Diaz-Sanchez
- Diego Sbardella
- Doerner
- Doi
- Domagala-Kulawik
- Dong
- Dong
- Du
- Du
- Dubois
- Duffy
- Dufour
- Dumin
- Dunn
- Durham
- D’Armiento
- D’Ercole
- Eckman
- Eckman
- Edwards
- Egeblad
- Ehrenfeld
- Eliason
- Elkington
- Elkington
- Elkins
- Ellenrieder
- Elnemr
- Emlen
- Emoto
- Endo
- England
- English
- English
- Erler
- Esser
- Ezhilarasan
- Fabriek
- Fager
- Fahrenholz
- Fainardi
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- Fasciglione
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- Ferro
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- Fingleton
- Finlay
- Fiore
- Fiotti
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- Flex
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- Furlan
- Furuse
- Gaetje
- Gakh
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- Galis
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- Galvez-Gastelum
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- Garg
- Garton
- Garvican
- Gaultier
- Gauthier
- Ge
- Genden
- Gerstein
- Ghaderian
- Giannelli
- Giannobile
- Gill
- Gill
- Gilles
- Gilles
- Gilles
- Gingras
- Gioia
- Gioia
- Gioia
- Gioia
- Giovanni Francesco Fasciglione
- Giricz
- Giricz
- Glass-Marmor
- Goldbach-Mansky
- Gondi
- Gottlieb
- Gough
- Gounni-Abdelilah
- Grazia Raffaella Tundo
- Gronski
- Gruber
- Grzmil
- Gu
- Guadamillas
- Gueders
- Guo
- Gutierrez-Fernandez
- Ha
- Haas
- Habelhah
- Hafezi-Moghadam
- Hahn
- Hahn
- Hamann
- Hanemaaijer
- Hansson
- Hansson
- Hansson
- Hao
- Haq
- Harrell
- Harrison
- Harty
- Hashimoto
- Hashimoto
- Hasty
- Hattori
- Hattori
- Hauser
- Hautamaki
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- Henderson
- Henderson
- Henderson
- Henney
- Heo
- Heo
- Herman
- Hernandez-Guillamon
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- Herrmann
- Hersh
- Heymans
- Heymans
- Hiden
- Hieta
- Hiller
- Himelstein
- Hiraoka
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- Hirose
- Hofmann
- Hohlbaum
- Hojilla
- Holman
- Holmbeck
- Hopkins
- Horton
- Hoshino
- Hotary
- Hotary
- Houghton
- Howard
- Hu
- Hu
- Huang
- Hulkkonen
- Hunninghake
- Huo
- Hwang
- Hägglund
- Ihling
- Ihling
- Ii
- Iida
- Iimuro
- Ikari
- Illman
- Illman
- Illman
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- Imai
- Impola
- Impola
- Inoue
- Iredale
- Ito
- Itoh
- Itoh
- Itoh
- Itoh
- Itoh
- Iwata
- Janssens
- Jaworski
- Jefferis
- Jeffries
- Jeng
- Jensen
- Jia
- Jian
- Jin
- Jo
- Joergensen
- Johansson
- Johansson
- Johansson
- Johnson
- Johnson
- Johnson
- Johnson
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- Jung
- Jung
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- Jüngel
- Kadono
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- Kang
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- Kim
- Kim
- Kim
- Kim
- Kim
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- Kiryu-Seo
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- Marchenko
- Mari
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- Martin
- Maskos
- Massimo Coletta
- Matrisian
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- Matsumoto
- Matsumoto
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- Matute-Bello
- Matziari
- Mauch
- Mazzocca
- McCawley
- McCawley
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- McQuibban
- Mehra
- Mercer
- Mewar
- Meyer
- Mias
- Michael
- Milner
- Milward
- Mimori
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- Min
- Minond
- Mitchell
- Miura
- Miyamori
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- Miyoshi
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- Mu
- Mudgett
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- Mueller
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- Muller
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- Munaut
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- Nakken
- Nap
- Neidhart
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- Nie
- Nie
- Niimi
- Nikkola
- Nilsson
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- Noel
- Noel
- Nolden
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- Noseworthy
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- Okada
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- Opdenakker
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- Ottl
- Overall
- Overall
- Overall
- Overall
- Owen
- Oxvig
- Oyamada
- O’Connell
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- Paganetti
- Page-McCaw
- Pagenstecher
- Pakozdi
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- Partridge
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- Patterson
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- Pei
- Pei
- Pei
- Pei
- Pei
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- Pyo
- Qu
- Qu
- Quantin
- Quaschning
- Quillard
- Ra
- Radichev
- Radjabi
- Ragin
- Ragin
- Rajah
- Rajoria
- Ram
- Ramirez
- Ramos-Fernandez
- Ranasinghe
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- Ratnikov
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- Red Eagle
- Redman
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- Reichel
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- Reiss
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- Rio
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- Rosenblum
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- Russell
- Saarialho-Kere
- Saarialho-Kere
- Sabatine
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- Sacre
- Sadler
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- Seiki
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- September
- Sha
- Shapiro
- Shapiro
- Shapiro
- Shapiro
- Shashkin
- Shenkman
- Shimada
- Shiomi
- Shirotani
- Shiryaev
- Shiryaev
- Shlopov
- Shofuda
- Shojaei
- Shrimpton
- Sigala
- Silence
- Siller-Lopez
- Sims
- Sirum
- Skiles
- Skiles
- Skoog
- Smith
- Sohail
- Sohail
- Song
- Song
- Sounni
- Sounni
- Sounni
- Sounni
- Sounni
- Spinale
- Sreedharan
- Stack
- Stack
- Stadlmann
- Standeven
- Stankovic
- Stanton
- Steenport
- Stefanidakis
- Stefano Marini
- Steffensen
- Stenman
- Sterchi
- Sternberg
- Sternlicht
- Sternlicht
- Sternlicht
- Stetler-Stevenson
- Stetler-Stevenson
- Stetler-Stevenson
- Stocker
- Stojic
- Stone
- Stracke
- Ståhle-Bäckdahl
- Su
- Sumitomo
- Sumitomo
- Sun
- Sun
- Sun
- Sun
- Suomela
- Swaisgood
- Swartz
- Swiderski
- Szabova
- Szabova
- Taddese
- Tak
- Takaishi
- Takino
- Takino
- Tam
- Tam
- Tamamura
- Tan
- Tanaka
- Tang
- Tanner
- Tchetverikov
- Tenenhouse
- Tester
- Tester
- Tetlow
- Tetlow
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- Thompson
- Théret
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- Turner
- Turner
- Turner
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- Ulrich
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- Uria
- Usmani
- Vaalamo
- Vaalamo
- Vaillant
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- Van den Steen
- Van den Steen
- Van den Steen
- Van den Steen
- Van den Steen
- Van den Steen
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- Van Lint
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- Vargo-Gogola
- Vazquez
- Veeravalli
- Velasco
- Velasco-Loyden
- Velinov
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- Vernier
- Verraes
- Viappiani
- Vincenti
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- Volcik
- Vos
- Vu
- Vu
- Wagstaff
- Wald
- Wallard
- Walling
- Walling
- Walsh
- Wang
- Wang
- Wang
- Wang
- Wang
- Wang
- Wang
- Wang
- Wang
- Wang
- Ware
- Warner
- Warner
- Warner
- Watson
- Weaver
- Wei
- Weingarten
- Wells
- Wells
- Werb
- Werner
- Werner
- Wernicke
- Weskamp
- Westhoff
- White
- Whitelock
- Widerlöv
- Wiegand
- Wielockx
- Wildeboer
- Wilkins-Port
- Williams
- Wilson
- Wilson
- Wilson
- Winkler
- Witty
- Woessner
- Wolf
- Wolfman
- Wright
- Wu
- Wu
- Wu
- Wysocki
- Wågsäter
- Wågsäter
- Xia
- Xiong
- Xu
- Xu
- Xu
- Xu
- Xu
- Xu
- Yamada
- Yamamoto
- Yamamoto
- Yamamoto
- Yamanaka
- Yan
- Yana
- Yana
- Yang
- Yang
- Yang
- Yavari
- Ye
- Ye
- Ye
- Yen
- Yoon
- Yoshihara
- Yoshizaki
- Yoshizaki
- Young
- Young
- Yu
- Yu
- Zeng
- Zhang
- Zhang
- Zhang
- Zhao
- Zhao
- Zhao
- Zhao
- Zheng
- Zhong
- Zhou
- Zhou
- Zhu
- Zijlstra
- Zitta
- Zucker
- Zuo
- Publication venue
- Publication date
- 01/04/2012
- Field of study
Human matrix metalloproteinases (MMPs) belong to the M10 family of the MA clan of endopeptidases. They are ubiquitarian enzymes, structurally characterized by an active site where a Zn(2+) atom, coordinated by three histidines, plays the catalytic role, assisted by a glutamic acid as a general base. Various MMPs display different domain composition, which is very important for macromolecular substrates recognition. Substrate specificity is very different among MMPs, being often associated to their cellular compartmentalization and/or cellular type where they are expressed. An extensive review of the different MMPs structural and functional features is integrated with their pathological role in several types of diseases, spanning from cancer to cardiovascular diseases and to neurodegeneration. It emerges a very complex and crucial role played by these enzymes in many physiological and pathological processes
Aufgaben und Werkzeuge der Verdauung
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1929
- Field of study
Studies on eriophyoid mites (Acari: Eriophyoidea) of Australia: A new genus and seven new species associated with tea trees, Melaleuca spp. (Myrtaceae)
- Author
- Amrine JW
- Amrine JW
- Amrine JW
- Baker EW
- Boczek J
- Boczek J
- Colton RT
- Davis R
- Dujardin F
- Evans G
- Halliday RB
- International Commission on Zoological Nomenclature
- Jeppson LR
- Keifer HH
- Keifer HH
- Keifer HH
- Keifer HH
- Lindquist EE
- Manson DCM
- Murtagh GJ
- Nalepa A
- Oldfield GN
- Pagenstecher HA
- Shi A
- Skoracka A
- Suharti M
- Suharti M
- von Siebold CTE
- Wrigley JW
- Publication venue
- 'Wiley'
- Publication date
- Field of study
Phytophagous and fungivorous mites (Acari: Prostigmata, Astigmata) from Peru
- Author
- Alata CJ.
- Alberto Daniel Guanilo
- Amrine JW
- André M.
- Ashmead WH.
- Ayala J.
- Baker EW
- Baker EW
- Baker EW
- Baker EW.
- Banks N.
- Banks N.
- Beer R.
- Boudreaux HB.
- Carlos H. W. Flechtmann
- Cooreman J.
- Croce M
- Denmark HA
- Denmark HA.
- Dupont LM.
- Ehara S.
- Ewing HE.
- Eyndhoven GL
- Flechtmann CHW.
- Fumouze A
- Geijskes DC.
- Gilberto José de Moraes
- Gonzales-Bustamante L.
- Gonzalez RH
- Guanilo AD
- Guanilo AD
- Guanilo AD
- Guanilo AD
- Guanilo AD
- Hirst S.
- Hirst S.
- Hughes AM.
- Keifer HH.
- Keifer HH.
- Keifer HH.
- Klimov PB
- Koch CL.
- Markus Knapp
- Marín R.
- Massee AM.
- McGregor EA.
- McGregor EA.
- McGregor EA.
- McGregor EA.
- McGregor EA.
- McGregor EA.
- Meyer MKPS.
- Michael AD.
- Oudemans AC.
- Pagenstecher HA.
- Pritchard AE
- Pritchard AE
- Procitrus
- Rahman KA
- Reck GF.
- Riley CV.
- Salazar J.
- Sayed MT.
- Smith FF
- Tuttle DM
- Vis RMJ de
- Wolfe H
- Zacher F.
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Cerebral cavernous malformations: from genes to proteins to disease
- Author
- Bicknell JM
- Bos JL
- Bouffard GG
- Béraud-Dufour S
- Cavé-Riant F
- Chang DD
- Clark JV
- Czubayko M
- Daniel D. Cavalcanti
- Davenport WJ
- Eerola I
- Felbor U
- Flocks JS
- Gianfrancesco F
- Glading AJ
- Green ED
- Green ED
- Greenberger S
- Guzeloglu-Kayisli O
- Hallmann R
- Henkemeyer M
- Hogan BM
- Justin Eales
- Kehrer-Sawatzki H
- Kere J
- Kidd HA
- Knudson AG
- Krebs LT
- Kufs H
- Kurth JH
- Laberge S
- Liquori CL
- Lonjon M
- Lucas M
- M. Yashar S. Kalani
- Ma X
- Mably JD
- Marchuk DA
- Mark C. Preul
- Mason I
- Matos P
- Michael JC
- Moussa R
- Nibert M
- Nikolay L. Martirosyan
- Otten P
- Pagenstecher A
- Pizon V
- Reedquist KA
- Robert F. Spetzler
- Ruggieri R
- Schouten JP
- Sedgwick SG
- Stahl S
- Verlaan DJ
- Voigt K
- Voss K
- Wang HU
- Wang Y
- Wienecke R
- Wojnowski L
- Zhang J
- Publication venue
- 'Journal of Neurosurgery Publishing Group (JNSPG)'
- Publication date
- 01/01/2012
- Field of study
Over the past half century molecular biology has led to great advances in our understanding of angio- and vasculogenesis and in the treatment of malformations resulting from these processes gone awry. Given their sporadic and familial distribution, their developmental and pathological link to capillary telangiectasias, and their observed chromosomal abnormalities, cerebral cavernous malformations (CCMs) are regarded as akin to cancerous growths. Although the exact pathological mechanisms involved in the formation of CCMs are still not well understood, the identification of 3 genetic loci has begun to shed light on key developmental pathways involved in CCM pathogenesis. Cavernous malformations can occur sporadically or in an autosomal dominant fashion. Familial forms of CCMs have been attributed to mutations at 3 different loci implicated in regulating important processes such as proliferation and differentiation of angiogenic precursors and members of the apoptotic machinery. These processes are important for the generation, maintenance, and pruning of every vessel in the body. In this review the authors highlight the latest discoveries pertaining to the molecular genetics of CCMs, highlighting potential new therapeutic targets for the treatment of these lesions
Genetics of vascular anomalies
- Author
- Akers
- Al-Olabi
- Alders
- Alders
- Amyere
- Au
- Ayturk
- Baranoski
- Boon
- Boon
- Boscolo
- Brice
- Brouillard
- Brouillard
- Brouillard
- Castel
- Castillo
- Chauviere
- Chen
- Chen
- Choi
- Choi
- Couto
- Couto
- Couto
- Couto
- Curry
- Dellinger
- Deng
- Dumont
- Duran
- Eerola
- Eng
- Fang
- Fastre
- Ferrell
- Finegold
- Flister
- Fujiwara
- Fukai
- Gallione
- Garrido-Martin
- Goines
- Gordon
- Goss
- Ha-Long Nguyen
- Hahle
- Hammer
- Hammill
- Hogan
- Hong
- Hu
- Irrthum
- Irrthum
- Jeltsch
- Jinnin
- Johnson
- Kanady
- Kazenwadel
- Kim
- Konczyk
- Kriederman
- Kulkarni
- Kume
- Kurek
- Lackner
- Laurence M. Boon
- Lekwuttikarn
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- Li
- Limaye
- Limaye
- Limaye
- Lindhurst
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- Mendola
- Mester
- Mester
- Miikka Vikkula
- Natynki
- Nguyen
- Nikolaev
- Odermatt
- Osborn
- Ostergaard
- Ostergaard
- Pagenstecher
- Park
- Pennisi
- Petrova
- Priemer
- Revencu
- Roberts
- Seront
- Shirley
- Shovlin
- Snellings
- Soblet
- Soblet
- Srinivasan
- Torsney
- Triana
- Tron
- Uebelhoer
- Uhlik
- Van Raamsdonk
- Venot
- Vikkula
- Vivanti
- Voss
- Wooderchak-Donahue
- Wouters
- Wustehube
- You
- Zawistowski
- Zhou
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
Current concepts and recent advances in the management of age-related macular degeneration
- Author
- A Kychenthal
- A Lowenstein
- A Scheider
- AC Bird
- AF Wright
- Age-Related Eye Disease Study Research Group
- BM Kenyon
- C Arlett
- C Eckardt
- Choroidal Neovascularisation Prevention Trial Research Group
- Choroidal Neovascularisation Prevention Trial Research Group
- D Husain
- D Hussain
- DB Archer
- DL Sherr
- DM Lanchoney
- DM Marcus
- G Coscas
- H Gerster
- H Lewis
- H Pagenstecher
- HA Kahn
- HS Rheinhold
- J Evans
- JDM Gass
- JR Vingerling
- KB Freund
- LD Pizzarello
- MA Thomas
- Macular Photocoagulation Study Group
- Macular Photocoagulation Study Group
- Macular Photocoagulation Study Group
- MJ Manyak
- NM Bressler
- P Mitchell
- PT Merrill
- PV Algvere
- R Klein
- R Machemer
- RF Spaide
- RHB Grey
- RJ D’Amato
- RJ Olk
- RSB Newsom
- RW Young
- S Beatty
- S Beatty
- S Byrne
- S Sharma
- S Sharma
- S Wolf
- SJ Fllesler
- Submacular Surgery Trials
- TA Ciulla
- TA Ciulla
- The Alpha-Tocopherol Beta Carotene Cancer Prevention Study G roup
- Treatment of Age-related Macular Degeneration with Photodynamic Therapy (TAP) Study Group
- U Chakravarthy
- U Schmidt-Erfurth
- WR Green
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Knockdown of the AKT3 (PKBγ), PI3KCA, and VEGFR2 genes by RNA interference suppresses glioblastoma multiforme T98G cells invasiveness in vitro
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- A Carnero
- A Damert
- A Krześlak
- A Krüger
- A Pagenstecher
- A Shay-Salit
- Adam Pudełko
- AH Baker
- Anna Fila-Daniłow
- AR Nelson
- AS Böhle
- AS Chan
- AS Chi
- AV Badiga
- B-H Jiang
- B-H Jiang
- BA Teicher
- BC Victor
- BD Manning
- C Hartmann
- C Perego
- C Wild-Bode
- C Xia
- CB Knobbe
- CD Young
- CJ Handley
- D Kim
- DE Gomez
- DG Stupack
- DS Tews
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- EC Holland
- EI Deryugina
- F Lefranc
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- FX Gomis-Rüth
- G Berchem
- G Giannelli
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- G Wolf
- GH Stein
- GJ Litherland
- GL Weber
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- H Fukuda
- H Mure
- H Nagase
- H Zhang
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- HA Burris
- HD Skinner
- J Bian
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- J Rutka
- J Westermarck
- J Zdychová
- JA Fresno Vara
- Jan Kowalski
- JH Qi
- K Zitzmann
- KA Descheemaeker
- KC Nannuru
- M Ahonen
- M Bond
- M Homsi El
- M Nakada
- M Nakada
- M Paul-Samojedny
- M Sivaparvathi
- Małgorzata Kowalczyk
- MC Mendoza
- MD Sternlicht
- Monika Paul-Samojedny
- MR Buck
- MR Sierra-Honigmann
- MS Wiesener
- N Bruggen Van
- N Ferrara
- N Pore
- N Pore
- ON Ozes
- P Carmeliet
- P Knizetova
- P Liu
- PA Forsyth
- Paulina Borkowska
- R Du
- R Maestro Del
- Renata Suchanek-Raif
- RL Jensen
- RS Ahima
- RW Matheny
- S Dias
- S Ghosh
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- S Szala
- S Uotani
- SJ Price
- SR Datta
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- T Yu
- V Duronio
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- W Wick
- W-L Yeh
- WG Stetler-Stevenson
- X-K Zhou
- Y Kudo
- Y Samuels
- Y-H Zhou
- YR Chin
- Z Kachra
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Die Vererbung von Augenleiden
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- A Baekan
- A Betsch
- A Bostroem
- A Bostroem
- A Boulanger
- A Bronner
- A Bruckner
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- A Brücxner
- A Busacca
- A Cantonnet
- A Darter
- A Darter
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- A Dutort
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- A Franceschetti
- A Francescjetti
- A Francesohetti
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- A Knapp
- A Knapp
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- A Lint
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- A Pagenstecher
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- A Patry
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- A Peiper
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- A Peters
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- AA Bradburne
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- AE Burroughs
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- AE Taft
- AH Griffith
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- AJ Liai
- AJ Schnee
- allgemeinen Bemerkungen über die Vererbung bei Augenleiden
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- Publication date
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- Field of study
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- Publication date
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- Field of study