111 research outputs found

    Análisis comparado del sistema de carrera administrativa con el sistema de nombramiento y libre remoción en la función pública colombiana

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    La presente investigación busca ampliar la literatura sobre la comparación de los cargos de libre nombramiento y remoción, desde el contexto histórico en que ambos se desarrollaron, hasta las diferencias jurídicas y funcionales, para así entender como se justifica la existencia de estas figuras en el estado social de derecho haciéndose la investigación por una metodología que parte del estudio de fuentes doctrinales, y así entender que ambas figuras son importantes en el estado social de derechos desde el aspecto de la función pública como las actividades del estado para cumplir sus fines constitucionalesUniversidad Libre de Colombia - Derecho AdministrativoThe present investigation seeks to expand the literature on the comparison of free appointment and removal positions, from the historical context in which both were developed, to the legal and functional differences, in order to understand how the existence of these figures in the state is justified. of law, making the investigation by a methodology that starts from the study of doctrinal sources, and thus understand that both figures are important in the social state of rights from the aspect of the public function as well as the activities of the state to fulfill its constitutional purposes

    Casos clínicos como estratégia didática para o ensino de bioquímica metabólica

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    The metabolism of the main types of biomolecules, their regulation and integration is one of the most complex and important issues for medical students. The implementation of a teaching-learning strategy based on the analysis of clinical cases, together with its corresponding discussion sessions, could be valid to help students build a solid and integrated knowledge of this important topic. This article describes our experience in the design and implementation of a learning strategy based on clinical cases, supported by periodic discussion sessions by students; The students involved found the experience satisfactory, formative and challenging, and they also had better performance in the evaluations developed with respect to students that were not related to the strategy.El metabolismo de los principales tipos de biomoléculas, su regulación e integración es uno de los temas más complejos e importantes para la formación de los futuros médicos. La implementación de una estrategia de enseñanza aprendizaje basada en el análisis de casos clínicos, junto con sus correspondientes sesiones de argumentación, puede resultar válida para ayudar a los estudiantes a construir un conocimiento sólido e integrado de este importante tema. El presente artículo describe nuestra experiencia en el diseño e implementación de una estrategia de aprendizaje basada en casos clínicos, apoyada con sesiones periódicas de argumentación por parte de los estudiantes; Los estudiantes involucrados encontraron la experiencia satisfactoria, formativa y retadora, además tuvieron mejor desempeño en las evaluaciones desarrolladas respecto a estudiantes que no tuvieron relación con la estrategia.  O metabolismo dos principais tipos de biomoléculas, sua regulação e integração é uma das questões mais complexas e importantes para a formação dos futuros médicos. A implementação de uma estratégia de ensino-aprendizagem baseada na análise de casos clínicos, juntamente com as respetivas sessões de discussão, pode ser válida para ajudar os alunos a construir um conhecimento sólido e integrado deste importante tema. Este artigo descreve a nossa experiência na concepção e implementação de uma estratégia de aprendizagem baseada em casos clínicos, apoiada em sessões periódicas de discussão pelos alunos; Os alunos envolvidos consideraram a experiência satisfatória, formativa e desafiadora, e também tiveram melhor desempenho nas avaliações desenvolvidas em relação aos alunos que não estavam relacionados à estratégia

    UNA NUEVA MIRADA A LA COMBUSTIÓN IN-SITU: TRATANDO DE ROMPER UN VIEJO PARADIGMA

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    RESUMENDado el creciente interés por el aumento en las reservas de crudo pesado en muchos países, entre estos Colombia, ha surgido la combustión in situ como un método alternativo para extraer petróleo pesado, donde otras técnicas, debido a las condiciones del yacimiento, no son las más apropiadas. Actualmente existe una considerable proporción de expertos en el ámbito petrolero, que no conciben la aplicación de dicha técnica en escala de campo debido a sus antecedentes. Por esta razón este artículo busca brindar al lector una percepción distinta de la técnica a partir de nuevas teorías y nuevas maneras de tratar un proceso de tan alta complejidad. En el presente estudio se establecen algunas consideraciones acerca de los mecanismos que se presentan, el origen y evolución de la técnica, variaciones de la técnica, pruebas de laboratorio, pautas para el modelamiento numérico y algunas consideraciones de diseño.Palabras claves: Combustión In situ, Inyección de Aire, Métodos de recobro mejorado de crudo, Crudos pesadosABSTRACTGiven the recent interest in increasing heavy oil reserves in many countries, Colombia among them, interest has been created for in situ combustion as an alternative method to extract oil where other techniques, provided the reservoir conditions, are not feasible. Nevertheless, there exists a significant amount of experts that do not conceive the application of this technique in a field scale due to its precedents. This article tries to give the reader a different view of the technique from new theories and new ways of treating a complex process as this one. Considerations regarding recovery mechanisms are presented, as well as the origin and evolution of the technique, its variations, laboratory tests, guidelines for numerical modeling and some design considerations.Keywords: In-Situ Combustion, Air Injection, Fire-flooding, Enhanced Oil Recovery, Heavy Oil

    Configuración servicio IPTV y calidad de servicio

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    No aplicaEn el presente documento se trabajó lo relacionado con el servicio de calidad (QoS) para las redes de nueva generación NGN, la configuración de los anchos de banda para la transmisión de tráfico web, tráfico de voz y para el tráfico de streaming de video teniendo en cuenta todas las consideraciones del caso y se implementó una transmisión de video a través de dos máquinas virtuales montadas en el programa de virtualización virtual Box teniendo en cuenta todos los protocolos de la tecnología Multicast para la configuración del servicio IPTV utilizando el reproductor de multimedia VCL y el simulador de redes GNS3 en el cual se montó la red para su simulación. Describimos el paso a paso de las diferentes configuraciones de los routers con imágenesIn this document, we worked on what is related to the quality of service (QoS) for the new generation NGN networks, the configuration of the bandwidths for the transmission of web traffic, voice traffic and for video streaming traffic having taking into account all the considerations of the case and a video transmission was implemented through two virtual machines mounted in the virtual Box virtualization program taking into account all the protocols of the multicast technology for the configuration of the IPTV service using the VCL multimedia player and the GNS3 network simulator in which the network was assembled for its simulation. We describe the step by step of the different configurations of the routers with images where the different commands used for this purpose are shown

    Expression of miRNA-106b in conventional renal cell carcinoma is a potential marker for prediction of early metastasis after nephrectomy

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    <p>Abstract</p> <p>Background</p> <p>MicroRNAs are endogenously expressed regulatory noncoding RNAs. Previous studies have shown altered expression levels of several microRNAs in renal cell carcinoma.</p> <p>Methods</p> <p>We examined the expression levels of selected microRNAs in 38 samples of conventional renal cell carcinoma (RCC) and 10 samples of non-tumoral renal parenchyma using TaqMan real-time PCR method.</p> <p>Results</p> <p>The expression levels of miRNA-155 (p < 0.0001), miRNA-210 (p < 0.0001), miRNA-106a (p < 0.0001) and miRNA-106b (p < 0.0001) were significantly over-expressed in tumor tissue, whereas the expression of miRNA-141 (p < 0.0001) and miRNA-200c (p < 0.0001) were significantly decreased in RCC samples. There were no significant differences between expression levels of miRNA-182 and miRNA-200b in tumor samples and renal parenchyma. Our data suggest that expression levels of miRNA-106b are significantly lower in tumors of patients who developed metastasis (p = 0.030) and miR-106b is a potential predictive marker of early metastasis after nephrectomy in RCC patients (long-rank p = 0.032).</p> <p>Conclusions</p> <p>We have confirmed previous observations obtained by miRNA microarray analysis using standardized real-time PCR method. For the first time, we have identified a prognostic significance of miRNA-106b, which, after validation on a larger group of patients, maybe useful as a promising biomarker in patients with RCC.</p

    Spin dynamics in semiconductors

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    This article reviews the current status of spin dynamics in semiconductors which has achieved a lot of progress in the past years due to the fast growing field of semiconductor spintronics. The primary focus is the theoretical and experimental developments of spin relaxation and dephasing in both spin precession in time domain and spin diffusion and transport in spacial domain. A fully microscopic many-body investigation on spin dynamics based on the kinetic spin Bloch equation approach is reviewed comprehensively.Comment: a review article with 193 pages and 1103 references. To be published in Physics Reports

    Semiconductor Spintronics

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    Spintronics refers commonly to phenomena in which the spin of electrons in a solid state environment plays the determining role. In a more narrow sense spintronics is an emerging research field of electronics: spintronics devices are based on a spin control of electronics, or on an electrical and optical control of spin or magnetism. This review presents selected themes of semiconductor spintronics, introducing important concepts in spin transport, spin injection, Silsbee-Johnson spin-charge coupling, and spindependent tunneling, as well as spin relaxation and spin dynamics. The most fundamental spin-dependent nteraction in nonmagnetic semiconductors is spin-orbit coupling. Depending on the crystal symmetries of the material, as well as on the structural properties of semiconductor based heterostructures, the spin-orbit coupling takes on different functional forms, giving a nice playground of effective spin-orbit Hamiltonians. The effective Hamiltonians for the most relevant classes of materials and heterostructures are derived here from realistic electronic band structure descriptions. Most semiconductor device systems are still theoretical concepts, waiting for experimental demonstrations. A review of selected proposed, and a few demonstrated devices is presented, with detailed description of two important classes: magnetic resonant tunnel structures and bipolar magnetic diodes and transistors. In most cases the presentation is of tutorial style, introducing the essential theoretical formalism at an accessible level, with case-study-like illustrations of actual experimental results, as well as with brief reviews of relevant recent achievements in the field.Comment: tutorial review; 342 pages, 132 figure

    Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

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    A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements
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