22 research outputs found
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Problems Associated with Making Mechanical Measurements on Water–Ice at Quasistatic and Dynamic Strain Rates
- Publication venue
- Journal of Dynamic Behavior of Materials
- Publication date
- 18/06/2020
- Field of study
Abstract: Space penetrators are a potential method of inserting instrumentation onto ice-covered bodies in the solar system. Part of a study to see whether this is feasible involves numerically simulating impact of the penetrator into ice at impact velocities of a few 100 m/s. In order to do this accurately, it is necessary to have a constitutive model for water ice that is valid at the strain rates and temperatures relevant to impact in the Outer Solar System. This paper reports certain issues and difficulties that arose during a study to obtain this data
Liberalization, globalization and the dynamics of democracy in India
- Author
- Aristotle
- Baumol William J.
- Brass Paul
- Cammack Paul
- Chadda Maya
- Chadda Maya
- Cohen Carl
- Dahl Robert A.
- de Schweinitz Karl
- Deaton Angus
- Diamond Larry
- Diamond Larry
- Easterlin Richard
- Flora Peter
- Friedman Benjamin
- Friedman Milton
- Gramsci Antonio
- Gunther Richard
- Hansda Sanjay
- Hayek Friedrich A.
- Hayek Friedrich A.
- Hirschman Albert
- Kohli Atul
- Kohli Atul
- Krueger Anne
- Kumar Rakesh
- Lijphart Arend
- Lindblom Charles E.
- Linz Juan
- Marx Karl
- Marx Karl
- Mill John S.
- Moore Barrington
- Neher Clark D.
- Offe Claus
- Olson Mancur
- Plekhanov George
- Poulantzas Nicos
- Putnam Robert D.
- Ravich Samantha F.
- Reisinger William M.
- Rizvi S. Abu Turab
- Rodrick Dani
- Rodrik Dani
- Roemer John
- Rueschemeyer Dietrich
- Schumpeter Joseph A.
- Sen Abhijit
- Shiller Robert J.
- Tullock Gordon
- Van der Veer Peter
- Weber Max
- Weber Max
- Weiner Myron
- Weitzman Martin L.
- Wood Adrian
- Publication venue
- Asia Research Centre, London School of Economics and Political Science
- Publication date
- 01/06/2010
- Field of study
In the closing decades of the twentieth century there has been an almost complete intellectual triumph of the twin principles of marketization (understood here as referring to the liberalization of domestic markets and freer international mobility of goods, services, financial capital and perhaps, more arguably, labour) and democratization . A paradigm shift of this extent and magnitude would not have occurred in the absence of some broad consensus among policymakers and (sections of) intellectuals around the globe on the desirability of such a change. There seems to be a two-fold causal nexus between marketization and democracy. The first is more direct, stemming from the fact of both systems sharing certain values and attitudes in common. But there is also a second more indirect chain from marketization to democracy, which is predicated via three sub-chains (i) from marketization to growth, (ii) from growth to overall material development welfare and (iii) from material development to social welfare and democracy. We examine each of these sub-links in detail with a view to obtaining a greater understanding of the hypothesized role of free markets in promoting democracies. In the later part of the paper we examine the socio-economic outcomes governing the quality of democracy in a specifically Indian context
Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
- Author
- Abbas M.
- Abdul Rasheed A.
- Abdul A.
- Abdul-Kadir R.
- Abdusamad K.
- Abernethy K.
- Aboelela H.
- Abouzaid M.
- Abraham M.
- Abraham T.
- Abrams J.
- Abu H.
- Abu-Arafeh A.
- Acton C.
- Adam F.
- Adam M.
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- Addo A.
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- Adegoke K.
- Adewunmi E.
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- Agbeko R.
- Aggarwal S.
- Ahmad S.
- Ahmed A.
- Ahmed I.
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- Ahmed R.
- Ainsworth M.
- Ajmi A.
- Akili S.
- Al Aaraj A.
- Al Balushi A.
- Al-Asadi A.
- Al-Khalil M.
- Al-Ramadhani B.
- Al-Saadi Z.
- Al-Shahi Salman R.
- Al-Sheklly B.
- Albert P.
- Alegria A.
- Alexander A.
- Alexander P.
- Alhabsha O.
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- Alin J.
- Aliyuda F.
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- Publication venue
- Springer Science and Business Media LLC
- Publication date
- 31/01/2024
- Field of study
Dimethyl fumarate (DMF) inhibits inflammasome-mediated inflammation and has been proposed as a treatment for patients hospitalised with COVID-19. This randomised, controlled, open-label platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]), is assessing multiple treatments in patients hospitalised for COVID-19 (NCT04381936, ISRCTN50189673). In this assessment of DMF performed at 27 UK hospitals, adults were randomly allocated (1:1) to either usual standard of care alone or usual standard of care plus DMF. The primary outcome was clinical status on day 5 measured on a seven-point ordinal scale. Secondary outcomes were time to sustained improvement in clinical status, time to discharge, day 5 peripheral blood oxygenation, day 5 C-reactive protein, and improvement in day 10 clinical status. Between 2 March 2021 and 18 November 2021, 713 patients were enroled in the DMF evaluation, of whom 356 were randomly allocated to receive usual care plus DMF, and 357 to usual care alone. 95% of patients received corticosteroids as part of routine care. There was no evidence of a beneficial effect of DMF on clinical status at day 5 (common odds ratio of unfavourable outcome 1.12; 95% CI 0.86-1.47; p = 0.40). There was no significant effect of DMF on any secondary outcome
Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
- Author
- Abbas M.
- Abdul Rasheed A.
- Abdul A.
- Abdul-Kadir R.
- Abdusamad K.
- Abernethy K.
- Aboelela H.
- Abouzaid M.
- Abraham M.
- Abraham T.
- Abrams J.
- Abu H.
- Abu-Arafeh A.
- Acton C.
- Adam F.
- Adam M.
- Adams C.
- Adams D.
- Adams L.
- Addo A.
- Adedeji O.
- Adegoke K.
- Adewunmi E.
- Adeyemo T.
- Agbeko R.
- Aggarwal S.
- Ahmad S.
- Ahmed A.
- Ahmed I.
- Ahmed M.
- Ahmed R.
- Ainsworth M.
- Ajmi A.
- Akili S.
- Al Aaraj A.
- Al Balushi A.
- Al-Asadi A.
- Al-Khalil M.
- Al-Ramadhani B.
- Al-Saadi Z.
- Al-Shahi Salman R.
- Al-Sheklly B.
- Albert P.
- Alegria A.
- Alexander A.
- Alexander P.
- Alhabsha O.
- Ali M.
- Aliberti E.
- Alin J.
- Aliyuda F.
- Alkhudhayri A.
- Allan N.
- Allanson A.
- Allen E.
- Allen L.
- Alshaer I.
- Altaf S.
- Amezaga M.
- Amin A.
- Amit B.
- Anand A.
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- Bujazia R.
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- Buttress D.
- Byrne J.
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- Byrne-Watts V.
- Cale E.
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- Caws C.
- Central Coordinating Office (for the RECOVERY Collaborative Group)
- Century H.
- Chadwick J.
- Chakkarapani E.
- Chakraborty A.
- Chamberlain S.
- Chambers E.
- Chambers L.
- Chan E.
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- Charles B.
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- Chatterton D.
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- Chauhan R.
- Chawla V.
- Chen F.
- Cheng F.
- Cherrie M.
- Cheung E.
- Cheyne C.
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- Chilvers A.
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- Chineka R.
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- Chiswick C.
- Chivima B.
- Chmiel C.
- Chrisopoulou A.
- Christian P.
- Christides A.
- Christmas D.
- Church E.
- Cianci N.
- Cicconi P.
- Clare E.
- Clark E.
- Clark G.
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- Clark R.
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- Clayton-Smith J.
- Cleaver C.
- Clemente de la Torre C.
- Clifford S.
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- Cocks S.
- Coe A.
- Coey D.
- Cohen D.
- Coker O.
- Cole J.
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- Collier D.
- Collini Paul
- Collins J.
- Collins V.
- Colton H.
- Condliffe R.
- Connell E.
- Connell L.
- Connelly K.
- Connolly G.
- Connor E.
- Conroy K.
- Conteh V.
- Conway R.
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- Cooke G.
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- Corbett C.
- Corbishley A.
- Cornwell J.
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- Cotterill D.
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- Darbyshire Janet
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- Data Monitoring Committee of the RECOVERY Collaborative Group
- Daunt A.
- Dave V.
- Davey M.
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- Dawson A.
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- de Silva T.
- De Soyza A.
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- Dear J.
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- Desai A.
- Deshpande S.
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- Dhani S.
- Dhasmana Devesh J.
- Dhillon R.
- Dicks P.
- Digby J.
- Dimitri P.
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- Dixon C.
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- Dobbie L.
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- Dolan D.
- Dolman M.
- Donald L.
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- Donohoe A.
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- Duggan A.
- Dummer S.
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- Dunleavy J.
- Dunn A.
- Duran B.
- Durrans L.
- Durrington H.
- Duru I.
- Dymond H.
- D’Costa J.
- D’Mello A.
- Eades C.
- Early J.
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- Edmond N.
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- Elgohary A.
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- Ellwood A.
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- Emberson Jonathan R.
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- Essa F.
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- Everden C.
- Everden S.
- Evison L.
- Ezenduka C.
- Fairbairn I.
- Fairclough A.
- Falconer E.
- Faluyi D.
- Fancois V.
- Farmery T.
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- Farrell B.
- Farzana S.
- Fatemi A.
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- Faust Saul N.
- Fearby S.
- Felton T.
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- Fenton C.
- Ferenando G.
- Ferguson C.
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- Ferguson V.
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- Fowler Robert
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- Health records (for the RECOVERY Collaborative Group)
- Hector G.
- Heddon S.
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- Johnstone E.
- Jones A.
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- Loader D.
- Local Clinical Centre staff (for the RECOVERY Collaborative Group)
- Lock S.
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- Logue C. A.
- Lokanathan S.
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- Saunderson A.
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- Shehata Z.
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- Sheppeard R.
- Sheridan H.
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- Shibly S.
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- Shillitoe B.
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- Publication venue
- Nature Publishing Group
- Publication date
- Field of study
Dimethyl fumarate (DMF) inhibits inflammasome-mediated inflammation and has been proposed as a treatment for patients hospitalised with COVID-19. This randomised, controlled, open-label platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]), is assessing multiple treatments in patients hospitalised for COVID-19 (NCT04381936, ISRCTN50189673). In this assessment of DMF performed at 27 UK hospitals, adults were randomly allocated (1:1) to either usual standard of care alone or usual standard of care plus DMF. The primary outcome was clinical status on day 5 measured on a seven-point ordinal scale. Secondary outcomes were time to sustained improvement in clinical status, time to discharge, day 5 peripheral blood oxygenation, day 5 C-reactive protein, and improvement in day 10 clinical status. Between 2 March 2021 and 18 November 2021, 713 patients were enroled in the DMF evaluation, of whom 356 were randomly allocated to receive usual care plus DMF, and 357 to usual care alone. 95% of patients received corticosteroids as part of routine care. There was no evidence of a beneficial effect of DMF on clinical status at day 5 (common odds ratio of unfavourable outcome 1.12; 95% CI 0.86-1.47; p = 0.40). There was no significant effect of DMF on any secondary outcome
Ruthenium(II) arene PTA (RAPTA) complexes: impact of enantiomerically pure arene ligands
- Publication venue
- 'Royal Society of Chemistry (RSC)'
- Publication date
- 26/03/2013
- Field of study
Organometallic ruthenium(II) arene complexes containing the PTA ligand ([Ru(eta(6)-arene)Cl-2(PTA)], PTA = 1,3,5-triaza-7-phosphatricyclo-[3.3.1.1] decane, termed RAPTA) show pharmacologically relevant antitumour properties in vitro. Two new enantiomeric pairs of RAPTA compounds, containing the chiral arene (R)- or (S)-2-phenyl-N-(1-phenylethylene) acetamide and either dichlorido or oxalato ligands were synthesised and fully characterised. The stability of the complexes towards hydrolysis was assessed and the dichlorido complexes were found to be more stable towards hydrolysis than the prototype complex RAPTA-C, ([Ru(eta(6)-p-cymene) Cl-2(PTA)]). The cytotoxicity of the compounds towards human ovarian cancer cells is moderate to good with a degree of selectivity towards the cancer cells over healthy cells. More significantly, for the first time we were able to establish the influence of a bulky, chiral group attached to the arene on the cytotoxicity of this class of compound, with the S-enantiomer being more cytotoxic than the R-enantiomer
Recommended from our members
A study of the compressive mechanical properties of defect-free, porous and sintered water-ice at low and high strain rates
- Publication venue
- ICARUS
- Publication date
- 01/01/2020
- Field of study
Thigh-length compression stockings and DVT after stroke
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- Abbasi S
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- Wood L
- Wood T
- Woodford J
- Woodhead L
- Woodland P
- Woodward Z
- Wooldridge G
- Woollen L
- Woosey D
- Wootton D
- Worton S
- Wright D
- Wright R
- Wroe C
- Wu P
- Wyness K
- Wynter I
- Xavier B
- Xia Z
- Yan M
- Yanney M
- Yasmin S
- Yates B
- Yates B
- Yates D
- Yates H
- Yein K
- Yelnoorkar F
- Yip K
- Ynter I
- Yorke J
- Youssouf S
- Yousuf A
- Yung B
- Zafar A-M
- Zaher S
- Zalewska K
- Zaman M
- Zaman S
- Zammit L
- Zammit-Mangion M
- Zdanaviciene A
- Zehnde D
- Zhixin J
- Zhu D
- Zia M
- Zin E Thant
- Zinyemba V
- Zipitis C
- Zmierczak A
- Zuhra N
- Zulaikha R
- Zullo C
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/07/1994
- Field of study
Controversy exists as to whether neoadjuvant chemotherapy improves survival in patients with invasive bladder cancer, despite randomised controlled trials of more than 3000 patients. We undertook a systematic review and meta-analysis to assess the effect of such treatment on survival in patients with this disease
The EU
- Author
- Berkes F.
- Cammack P.
- Chandler D.
- Commission of the European Communities
- Department for International Development (DFID)
- Duffield M.
- European Commission
- European Council
- Federal Democratic Republic of Ethiopia
- Federal Democratic Republic of Ethiopia
- Headey D.
- Jonathan Joseph
- Klugman J.
- Merlingen M.
- Parker O.
- United States Agency for International Development (USAID)
- Venton C.C.
- World Resources Institute (WRI) United Nations Development Programme (UNDP), United Nations Environment Programme (UNEP) and World Bank
- Publication venue
- 'Wiley'
- Publication date
- 23/10/2013
- Field of study
Segregation, Ethnic Favoritism, and the Strategic Targeting of Local Public Goods
- Author
- Adida C.
- Amanda Lea Robinson
- Bates R.
- Baumann E.
- Cammack D.
- Chinsinga B.
- Chinsinga B.
- Chinsinga B.
- Chirwa E.
- Chiweza A. L.
- De Luca G.
- DeGabriele J.
- Eric Kramon
- Ferguson A.
- Gilman L.
- Government of Malawi
- Government of Malawi
- Habyarimana J. P.
- Joseph R.
- Kramon E.
- Matuszeski J.
- Minnesota Population Center
- MP commissions K1.6m borehole in Zomba
- National Statistical Office of Malawi and ORC Macro
- Simon Ejdemyr
- Strandow D.
- Tajfel H.
- Tsoka M.
- Vail L.
- Velasquez M.
- WaterAid
- WaterAid
- Wooldridge J. M.
- Øygard R.
- Øygard R.
- Publication venue
- 'SAGE Publications'
- Publication date
- Field of study
Southeast Asia in the New Global Economy: Emerging Challenges from Africa and Latin America
- Author
- Achyles Costa
- Adb/Idb
- Akansha Awal
- Alejandro Izquierdo
- Alicia Garcia-Herrero
- Andrea Goldstein
- Andrea Goldstein
- Chantal Dupasquier
- Chris Alden
- Deborah Br�utigam
- Deborah Br�utigam
- Douglas Zeng
- Eliana Cardoso
- Elizabeth Sidiropolous
- Giles Mohan
- Harry G Broadman
- Ian Coxhead
- Ian Taylor
- Idb
- Imf
- James Lamont
- Javier Cravino
- Jing Gu
- Joseph Cheng
- Justin Lin
- Justin Lin
- Juthathip Jongwanich
- Kevin P Gallagher
- Kungwang Li
- Luis Moreno
- Marco Sanfilippo
- Martin Ravallion
- Martyn Davies
- Mary-Fran�oise Renard
- Nargiza Salidjanova
- Oecd
- Otaviano Canuto
- Paul Cammack
- R Zoellick
- Raphael Kaplinsky
- Razeen Sally
- Renato Aguilar
- Rhys Jenkins
- Richard Schiere
- Ruben Gonzalez-Vicente
- Seifudein Adem
- Shandre M Thangavelu
- Simon Mundy
- Tegegne Gebre-Egziabher
- Vivien Foster
- World Bank
- World Bank
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2011
- Field of study