1,881 research outputs found

    Plan de marketing para la bebida Bio Camu de AJEPER S.A.

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    El presente trabajo tiene como objetivo realizar el plan de marketing para un nuevo producto del grupo AJE llamado BIO Camu. En primer lugar, hicimos análisis del ambiente interno, seguido por uno de recursos, VRIO (valor, rareza, imitabilidad y organización); y del macro y micro ambiente. Estos análisis nos sirvieron para identificar los principales atributos de AJEPER S.A., así como factores que resaltaron en cuanto a fortalezas, debilidades, oportunidades y amenazas. Luego, se investigó al cliente, para entender la percepción de los consumidores. Para ello, se utilizó una metodología de tipo cualitativo y cuantitativo. La primera, consistió en trabajar con dos grupos focales. La parte cuantitativa consistió en elaborar una encuesta para conocer el atractivo del producto en el mercado peruano de bebidas saludables. Asimismo, diseñamos un canal de Marketing mix. Finalmente, se calculó una proyección de ventas de 3,460,500 unidades anuales. En conclusión, el proyecto se calificó como viable para AJE

    The types and categories of old english recursive compounding

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    [EN] This article deals with the recursive compounding of Old English nouns, adjectives, verbs and adverbs. It addresses the question of the textual occurrences of the compounds of Old English by means of a corpus analysis based on the Dictionary of Old English Corpus. The data of qualitative analysis have been retrieved from the lexical database of Old English Nerthus. The analysis shows that the nominal, adjectival and adverbial compounds of Old English can be recursive. Nominal compounding allows double recursivity, whereas adjectival and adverbial compounding do not. The conclusion is reached that both the type and token frequencies of recursive compounds are very low; and recursive compounds from the adjectival class are more exocentric as regards categorisationThis research has been funded through the grant FFI2014-59110 (MINECO), which is gratefully acknowledged.Novo Urraca, C. (2017). The types and categories of old english recursive compounding. Revista de Lingüística y Lenguas Aplicadas. 12. https://doi.org/10.4995/rlyla.2017.7161SWORD8612BAAYEN, H., & LIEBER, R. (1991). Productivity and English derivation: a corpus-based study. Linguistics, 29(5). doi:10.1515/ling.1991.29.5.801Bauer, L. (2008). A Glossary of Morphology. Edimburgh: Edimburgh University Press.Bosworth, J. and Toller, T. N. 1973 (1898). An Anglo-Saxon Dictionary. Oxford: Oxford University Press.Brinton, L. J., & Traugott, E. C. (2005). Lexicalization and Language Change. doi:10.1017/cbo9780511615962Campbell, A. (1972). An Anglo-Saxon Dictionary: Enlarged addenda and corrigenda. Oxford: Clarendon Press.Carr, C.T. (1939). Nominal Compounds in Germanic. St. Andrews: St. Andrews University Publication.García García, L. (2012). Morphological Causatives in Old English: the Quest for a Vanishing Formation1. Transactions of the Philological Society, 110(1), 122-148. doi:10.1111/j.1467-968x.2012.01287.xGarcía García, L. (2013). "Lexicalization and morphological simplification in Old English jan-causatives: some open questions". Sprachwissenschaft, 38/2: 245-264.González Torres, E. (2010a). "The Continuum Inflection-Derivation and the Old English suffixes -a, -e, -o, -u". Atlantis, 32/1: 103-122.González Torres, E. (2010b). "The bases of derivation of Old English affixed nouns: status and category". Studia Anglica Posnaniensia, 46/2: 21-43.González Torres, E. (2011). "Morphological complexity, recursiveness and templates in the formation of Old English nouns". Estudios Ingleses de la Universidad Complutense, 19: 45-70.Kastovsky, D. (s. f.). SEMANTICS AND VOCABULARY. The Cambridge History of the English Language, 290-408. doi:10.1017/chol9780521264747.006Martín Arista, J. (2012a). "Lexical database, derivational map and 3D representation". RESLA-Revista Espa-ola de Lingüística Aplicada, Extra 1: 119-144.Arista, J. M. (2012). The Old English Prefixge-: A Panchronic Reappraisal. Australian Journal of Linguistics, 32(4), 411-433. doi:10.1080/07268602.2012.744264Arista, J. M. (2013). Recursivity, Derivational Depth and the Search for Old English Lexical Primes. Studia Neophilologica, 85(1), 1-21. doi:10.1080/00393274.2013.771829Martín Arista, J. (2014). "Noun layers in Old English. Asymmetry and mismatches in lexical derivation". Nordic Journal of English Studies, 13/3: 160-187.Martín Arista, J. "El paradigma derivativo del inglés antiguo". Onomazeín. Forthcoming-a.Martín Arista, J. "The Semantic Poles of Old English. Towards the 3D Representation of Complex Polysemy". Digital Scholarship in the Humanities. Forthcoming-b.Martín Arista, J., & Cortés Rodriguez, F. J. (2014). From directionals to telics. Theory and Practice in Functional-Cognitive Space, 229-250. doi:10.1075/sfsl.68.10marMateo Mendaza, R. (2013). The Old English Exponent for the Semantic Prime TOUCH. Descriptive and Methodological Questions. Australian Journal of Linguistics, 33(4), 449-466. doi:10.1080/07268602.2013.857574Mateo Mendaza, R. (2015a). "Matching productivity indexes and diachronic evolution. The Old English affixes ful-, -isc, -cund and -ful". Canadian Journal of Linguistics, 60/1: 1-24.Mateo Mendaza, R. (2015b). "The search for Old English semantic primes: the case of HAPPEN". Nordic Journal of English Studies, 15: 71-99.Mateo Mendaza, R. (2016). The Old English Exponent for the Semantic Prime MOVE*. Australian Journal of Linguistics, 36(4), 542-559. doi:10.1080/07268602.2016.1169976Novo Urraca, C. (2016). Old English Suffixation: Content and Transposition. English Studies, 97(6), 638-655. doi:10.1080/0013838x.2016.1183955Novo Urraca, C. (2016). Morphological Relatedness and the Typology of Adjectival Formations in Old English. Studia Neophilologica, 88(1), 43-55. doi:10.1080/00393274.2016.1150788Plag, I. (1999). Morphological Productivity. doi:10.1515/9783110802863Sweet, H. 1976 (1896). The student's Dictionary of Anglo-Saxon. Cambridge: Cambridge University Press.Toller, T. N. (1921). An Anglo-Saxon Dictionary: Supplement. Oxford: Clarendon Press.Torre Alonso, R. (2011a). "The Morphological Structure of Old English Complex Nouns". Atlantis, 33/1: 127-146.Torre Alonso, R. (2011b). "Affix Combination in Old English Noun Formation: Distribution and Constraints". RESLARevista Espa-ola de Linguística Aplicada, 24: 257-278.Vea Escarza, R. (2012). Structural and Functional Aspects of Morphological Recursivity. NOWELE, 64-65, 155-179. doi:10.1075/nowele.64-65.09escVea Escarza, R. (2013). OLD ENGLISH ADJECTIVAL AFFIXATION: STRUCTURE AND FUNCTION. Studia Anglica Posnaniensia, 48(2-3), 5-25. doi:10.2478/stap-2013-0005Vea Escarza, R. (2014). Split and unified functions in the formation of old English nouns and adjectives. Revista de Lingüística y Lenguas Aplicadas, 9(1), 106. doi:10.4995/rlyla.2014.2086Vea Escarza, R. (2015). Recursivity and Inheritance in the Formation of Old English Nouns and Adjectives. Studia Neophilologica, 88(1), 1-23. doi:10.1080/00393274.2015.1049830Vea Escarza, R. (2016b). "Old English affixation. A structural-functional analysis". Nordic Journal of English Studies, 15/1: 101-119

    International consensus on (ICON) anaphylaxis

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    ICON: Anaphylaxis provides a unique perspective on the principal evidence-based anaphylaxis guidelines developed and published independently from 2010 through 2014 by four allergy/immunology organizations. These guidelines concur with regard to the clinical features that indicate a likely diagnosis of anaphylaxis -- a life-threatening generalized or systemic allergic or hypersensitivity reaction. They also concur about prompt initial treatment with intramuscular injection of epinephrine (adrenaline) in the mid-outer thigh, positioning the patient supine (semi-reclining if dyspneic or vomiting), calling for help, and when indicated, providing supplemental oxygen, intravenous fluid resuscitation and cardiopulmonary resuscitation, along with concomitant monitoring of vital signs and oxygenation. Additionally, they concur that H1-antihistamines, H2-antihistamines, and glucocorticoids are not initial medications of choice. For self-management of patients at risk of anaphylaxis in community settings, they recommend carrying epinephrine auto-injectors and personalized emergency action plans, as well as follow-up with a physician (ideally an allergy/immunology specialist) to help prevent anaphylaxis recurrences. ICON: Anaphylaxis describes unmet needs in anaphylaxis, noting that although epinephrine in 1 mg/mL ampules is available worldwide, other essentials, including supplemental oxygen, intravenous fluid resuscitation, and epinephrine auto-injectors are not universally available. ICON: Anaphylaxis proposes a comprehensive international research agenda that calls for additional prospective studies of anaphylaxis epidemiology, patient risk factors and co-factors, triggers, clinical criteria for diagnosis, randomized controlled trials of therapeutic interventions, and measures to prevent anaphylaxis recurrences. It also calls for facilitation of global collaborations in anaphylaxis research. In addition to confirming the alignment of major anaphylaxis guidelines, ICON: Anaphylaxis adds value by including summary tables and citing 130 key references. It is published as an information resource about anaphylaxis for worldwide use by healthcare professionals, academics, policy-makers, patients, caregivers, and the public

    Search for direct production of charginos and neutralinos in events with three leptons and missing transverse momentum in √s = 7 TeV pp collisions with the ATLAS detector

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    A search for the direct production of charginos and neutralinos in final states with three electrons or muons and missing transverse momentum is presented. The analysis is based on 4.7 fb−1 of proton–proton collision data delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with Standard Model expectations in three signal regions that are either depleted or enriched in Z-boson decays. Upper limits at 95% confidence level are set in R-parity conserving phenomenological minimal supersymmetric models and in simplified models, significantly extending previous results

    Search for squarks and gluinos in events with isolated leptons, jets and missing transverse momentum at s√=8 TeV with the ATLAS detector

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    The results of a search for supersymmetry in final states containing at least one isolated lepton (electron or muon), jets and large missing transverse momentum with the ATLAS detector at the Large Hadron Collider are reported. The search is based on proton-proton collision data at a centre-of-mass energy s√=8 TeV collected in 2012, corresponding to an integrated luminosity of 20 fb−1. No significant excess above the Standard Model expectation is observed. Limits are set on supersymmetric particle masses for various supersymmetric models. Depending on the model, the search excludes gluino masses up to 1.32 TeV and squark masses up to 840 GeV. Limits are also set on the parameters of a minimal universal extra dimension model, excluding a compactification radius of 1/R c = 950 GeV for a cut-off scale times radius (ΛR c) of approximately 30

    Measurement of the production of a W boson in association with a charm quark in pp collisions at √s = 7 TeV with the ATLAS detector

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    The production of a W boson in association with a single charm quark is studied using 4.6 fb−1 of pp collision data at s√ = 7 TeV collected with the ATLAS detector at the Large Hadron Collider. In events in which a W boson decays to an electron or muon, the charm quark is tagged either by its semileptonic decay to a muon or by the presence of a charmed meson. The integrated and differential cross sections as a function of the pseudorapidity of the lepton from the W-boson decay are measured. Results are compared to the predictions of next-to-leading-order QCD calculations obtained from various parton distribution function parameterisations. The ratio of the strange-to-down sea-quark distributions is determined to be 0.96+0.26−0.30 at Q 2 = 1.9 GeV2, which supports the hypothesis of an SU(3)-symmetric composition of the light-quark sea. Additionally, the cross-section ratio σ(W + +c¯¯)/σ(W − + c) is compared to the predictions obtained using parton distribution function parameterisations with different assumptions about the s−s¯¯¯ quark asymmetry

    Search for squarks and gluinos with the ATLAS detector in final states with jets and missing transverse momentum using √s=8 TeV proton-proton collision data

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    A search for squarks and gluinos in final states containing high-p T jets, missing transverse momentum and no electrons or muons is presented. The data were recorded in 2012 by the ATLAS experiment in s√=8 TeV proton-proton collisions at the Large Hadron Collider, with a total integrated luminosity of 20.3 fb−1. Results are interpreted in a variety of simplified and specific supersymmetry-breaking models assuming that R-parity is conserved and that the lightest neutralino is the lightest supersymmetric particle. An exclusion limit at the 95% confidence level on the mass of the gluino is set at 1330 GeV for a simplified model incorporating only a gluino and the lightest neutralino. For a simplified model involving the strong production of first- and second-generation squarks, squark masses below 850 GeV (440 GeV) are excluded for a massless lightest neutralino, assuming mass degenerate (single light-flavour) squarks. In mSUGRA/CMSSM models with tan β = 30, A 0 = −2m 0 and μ > 0, squarks and gluinos of equal mass are excluded for masses below 1700 GeV. Additional limits are set for non-universal Higgs mass models with gaugino mediation and for simplified models involving the pair production of gluinos, each decaying to a top squark and a top quark, with the top squark decaying to a charm quark and a neutralino. These limits extend the region of supersymmetric parameter space excluded by previous searches with the ATLAS detector

    Evidence for the Higgs-boson Yukawa coupling to tau leptons with the ATLAS detector

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    Results of a search for H → τ τ decays are presented, based on the full set of proton-proton collision data recorded by the ATLAS experiment at the LHC during 2011 and 2012. The data correspond to integrated luminosities of 4.5 fb−1 and 20.3 fb−1 at centre-of-mass energies of √s = 7 TeV and √s = 8 TeV respectively. All combinations of leptonic (τ → `νν¯ with ` = e, µ) and hadronic (τ → hadrons ν) tau decays are considered. An excess of events over the expected background from other Standard Model processes is found with an observed (expected) significance of 4.5 (3.4) standard deviations. This excess provides evidence for the direct coupling of the recently discovered Higgs boson to fermions. The measured signal strength, normalised to the Standard Model expectation, of µ = 1.43 +0.43 −0.37 is consistent with the predicted Yukawa coupling strength in the Standard Model

    Measurement of the charge asymmetry in dileptonic Decays of top quark pairs in pp collisions at √ s = 7 TeV using the ATLAS detector

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    A measurement of the top-antitop (tt) charge asymmetry is presented using data corresponding to an integrated luminosity of 4.6 fb −1 of LHC pp collisions at a centre- of-mass energy of 7 TeV collected by the ATLAS detector. Events with two charged leptons, at least two jets and large missing transverse momentum are selected. Two observables are studied: A tt/C, based on the reconstructed tt final state. The asymmetries are measured to be A ll/C = 0.024 +/- 0.015 (stat.) +/- 0.009 (syst.) Att/C = 0.021 +/- 0.025 (stat.) +/- 0.017 (syst.) The measured values are in agreement with the Standard Model predictions

    Host Antimicrobial Peptides: the promise of new treatment strategies against Tuberculosis

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    Tuberculosis (TB) continues to be a devastating infectious disease and remerges as a global health emergency due to an alarming rise of antimicrobial resistance to its treatment. Despite of the serious effort that has been applied to develop effective antitubercular chemotherapies, the potential of antimicrobial peptides (AMPs) remains underexploited. A large amount of literature is now accessible on the AMP mechanisms of action against a diversity of pathogens; nevertheless, research on their activity on mycobacteria is still scarce. In particular, there is an urgent need to integrate all available interdisciplinary strategies to eradicate extensively drug-resistant Mycobacterium tuberculosis strains. In this context, we should not underestimate our endogenous antimicrobial proteins and peptides as ancient players of the human host defense system. We are confident that novel antibiotics based on human AMPs displaying a rapid and multifaceted mechanism, with reduced toxicity, should significantly contribute to reverse the tide of antimycobacterial drug resistance. In this review, we have provided an up to date perspective of the current research on AMPs to be applied in the fight against TB. A better understanding on the mechanisms of action of human endogenous peptides should ensure the basis for the best guided design of novel antitubercular chemotherapeutics
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