80 research outputs found
Instruments and Methods: Direct measurement of sliding at the glacier bed
- Publication venue
- 'International Glaciological Society'
- Publication date
- 01/01/1994
- Field of study
Sliding at the base of Trapridge Glacier, Yukon Territory, Canada, was measured using a “drag spool”. We describe this simple and inexpensive instrument as well as its installation and operation. From 1990 to 1992 seven sites were instrumented with drag spools. At six of the sites basal sliding, during the period of observation, accounted for 50-70% of the total flow observed at the glacier surface. The contribution from ice creep is known to be small, so most of the remaining surface motion must be attributed to subglacial sediment deformation. For the seventh site the observed sliding rate was ~ 90% of the total flow, an indication that the sliding contribution varies spatially across the bed. Diurnal variations in the response of one of our instruments appear to be correlated to subglacial water-pressure fluctuations and are interpreted in terms of changes in sliding velocity rather than the opening and closing of basal cavities
Instruments and Methods: Direct measurement of sliding at the glacier bed
- Publication venue
- 'International Glaciological Society'
- Publication date
- 01/01/1994
- Field of study
Sliding at the base of Trapridge Glacier, Yukon Territory, Canada, was measured using a “drag spool”. We describe this simple and inexpensive instrument as well as its installation and operation. From 1990 to 1992 seven sites were instrumented with drag spools. At six of the sites basal sliding, during the period of observation, accounted for 50-70% of the total flow observed at the glacier surface. The contribution from ice creep is known to be small, so most of the remaining surface motion must be attributed to subglacial sediment deformation. For the seventh site the observed sliding rate was ~ 90% of the total flow, an indication that the sliding contribution varies spatially across the bed. Diurnal variations in the response of one of our instruments appear to be correlated to subglacial water-pressure fluctuations and are interpreted in terms of changes in sliding velocity rather than the opening and closing of basal cavities
Structural Optimization and De Novo Design of Dengue Virus Entry Inhibitory Peptides
- Author
- B Sainz Jr
- BK Thaisomboonsuk
- C Wild
- C Wild
- CR Rees
- Craig R. Rees
- DE Volk
- DH Clarke
- DM Morens
- DS Burke
- E Huang
- Ekachai Jenwitheesuk
- Elizabeth Hunsperger
- Eva Harris
- F Bai
- FA Rey
- FX Heinz
- GE Nybakken
- Joshua M. Costin
- JS Mackenzie
- JS Schieffelin
- K Stiasny
- K Whitby
- KC Huang
- Kelly A. Conrads
- Krystal A. Fontaine
- LV Chernomordik
- M Levitt
- M Levitt
- M Levitt
- Michael G. Rossmann
- MJ Bower
- N Metropolis
- NM Qureshi
- R Kanai
- R Samudrala
- Ram Samudrala
- RF Garry
- S Bressanelli
- S Chutinimitkul
- S Yu
- SB Halstead
- SB Halstead
- SB Halstead
- SC Harrison
- SC Kliks
- Scott F. Michael
- Sharon Isern
- Shee-Mei Lok
- SM Lok
- VK Ganesh
- Y Modis
- Y Modis
- Y Modis
- Y Zhang
- YM Hrobowski
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2010
- Field of study
Viral fusogenic envelope proteins are important targets for the development of inhibitors of viral entry. We report an approach for the computational design of peptide inhibitors of the dengue 2 virus (DENV-2) envelope (E) protein using high-resolution structural data from a pre-entry dimeric form of the protein. By using predictive strategies together with computational optimization of binding “pseudoenergies”, we were able to design multiple peptide sequences that showed low micromolar viral entry inhibitory activity. The two most active peptides, DN57opt and 1OAN1, were designed to displace regions in the domain II hinge, and the first domain I/domain II beta sheet connection, respectively, and show fifty percent inhibitory concentrations of 8 and 7 µM respectively in a focus forming unit assay. The antiviral peptides were shown to interfere with virus:cell binding, interact directly with the E proteins and also cause changes to the viral surface using biolayer interferometry and cryo-electron microscopy, respectively. These peptides may be useful for characterization of intermediate states in the membrane fusion process, investigation of DENV receptor molecules, and as lead compounds for drug discovery
Nanostructural Diversity of Synapses in the Mammalian Spinal Cord
- Author
- A Bayés
- A Bayés
- A Covelo
- A Derouiche
- A Dosemeci
- A Du Beau
- A Dvorzhak
- A Panatier
- A Ribeiro-da-Silva
- A-H Tang
- AJ Todd
- AJ Todd
- B Walmsley
- BS Khakh
- C Schitine
- CE Junge
- CG Specht
- CR Sunico
- CS Chiu
- D Acton
- D Choquet
- D Nair
- DM Hegarty
- DY Weng
- E Beamer
- EC Witts
- EC Witts
- EM Carlsen
- EM Garry
- F Clarac
- F Tao
- F Tao
- FJ Alvarez
- G Perea
- H Husi
- H Ikeda
- H Varoqui
- HD MacGillavry
- J Spacek
- J-F Gilles
- J-M Masch
- JB Foster
- JG Emsley
- JM Wilson
- JN Betley
- JP Heller
- K Yamada
- KC Crosby
- KKL Liu
- KM Harris
- KM Harris
- L Chen
- LE Clarke
- LL Glickfeld
- LR Herron
- LS Chaboub
- M Haber
- M Hruska
- M Lavialle
- M Rèthelyi
- MC Lagerström
- MC Weston
- MD Abbinanti
- MI Arbuckle
- MJ Broadhead
- MO Collins
- O Kopach
- O Tarabal
- P Brumovsky
- P Caroni
- PR Brumovsky
- Q Sun
- R Ventura
- RA Frank
- RAW Frank
- RT Fremeau
- RT Fremeau
- S Okabe
- S Persson
- SA Sloan
- SM Wojcik
- T Brännström
- TJ Ryan
- TM DeSilva
- TM Newpher
- W Wegner
- Y Fukata
- Y Geinisman
- Y Geinisman
- Y Ni
- Y Ota
- Y-X Tao
- À Bayés
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 18/05/2020
- Field of study
This work for funded by the Biotechnology and Biological Sciences Research Council (BBSRC; BB/M021793/1), RS MacDonald Charitable Trust, Motor Neurone Disease (MND) Association UK (Miles/Apr18/863-791), the Engineering and Physical Sciences Research Council (EPSRC; EP/P030017/1), Welcome Trust (202932/Z/16/Z), European Research Council (ERC; 695568) and the Simons Initiative for the Developing Brain.Functionally distinct synapses exhibit diverse and complex organisation at molecular and nanoscale levels. Synaptic diversity may be dependent on developmental stage, anatomical locus and the neural circuit within which synapses reside. Furthermore, astrocytes, which align with pre and post-synaptic structures to form “tripartite synapses”, can modulate neural circuits and impact on synaptic organisation. In this study, we aimed to determine which factors impact the diversity of excitatory synapses throughout the lumbar spinal cord. We used PSD95-eGFP mice, to visualise excitatory postsynaptic densities (PSDs) using high-resolution and super-resolution microscopy. We reveal a detailed and quantitative map of the features of excitatory synapses in the lumbar spinal cord, detailing synaptic diversity that is dependent on developmental stage, anatomical region and whether associated with VGLUT1 or VGLUT2 terminals. We report that PSDs are nanostructurally distinct between spinal laminae and across age groups. PSDs receiving VGLUT1 inputs also show enhanced nanostructural complexity compared with those receiving VGLUT2 inputs, suggesting pathway-specific diversity. Finally, we show that PSDs exhibit greater nanostructural complexity when part of tripartite synapses, and we provide evidence that astrocytic activation enhances PSD95 expression. Taken together, these results provide novel insights into the regulation and diversification of synapses across functionally distinct spinal regions and advance our general understanding of the ‘rules’ governing synaptic nanostructural organisation.Publisher PDFPeer reviewe
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
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- A. -G. Wu
- A. C. Ma
- A. K. Au
- Abdel-Aziz A. K.
- Abdelfatah S.
- Abdellatif M.
- Abdoli A.
- Abel S.
- Abeliovich H.
- Abildgaard M. H.
- Abudu Y. P.
- Acevedo-Arozena A.
- Adamopoulos I. E.
- Adeli K.
- Adolph T. E.
- Adornetto A.
- Aflaki E.
- Agam G.
- Agarwal A.
- Aggarwal B. B.
- Agnello M.
- Agostinis P.
- Agrewala J. N.
- Agrotis A.
- Aguilar P. V.
- Ahmad S. T.
- Ahmed Z. M.
- Ahumada-Castro U.
- Aits S.
- Aizawa S.
- Akkoc Y.
- Akoumianaki T.
- Akpinar H. A.
- Al-Abd A. M.
- Al-Akra L.
- Al-Gharaibeh A.
- Alaoui-Jamali M. A.
- Alberti S.
- Alcocer-Gomez E.
- Alessandri C.
- Ali M.
- Alim Al-Bari M. A.
- Aliwaini S.
- Alizadeh J.
- Almacellas E.
- Almasan A.
- Alonso A.
- Alonso G. D.
- Altan-Bonnet N.
- Altieri D. C.
- Alvarez E. M. C.
- Alves da Costa C.
- Alves S.
- Alzaharna M. M.
- Amadio M.
- Amantini C.
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- Ambrosio S.
- Amer A. O.
- Ammanathan V.
- An Z.
- Andersen S. U.
- Andrabi S. A.
- Andrade-Silva M.
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- Ansari M. Y.
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- Antebi A.
- Anton Z.
- Anwar T.
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- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2021
- Field of study
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
- Author
- Abdel-Aziz AK
- Abdelfatah S
- Abdellatif M
- Abdoli A
- Abel S
- Abeliovich H
- Abildgaard MH
- Abudu YP
- Acevedo-Arozena A
- Adamopoulos IE
- Adeli K
- Adolph TE
- Adornetto A
- Aflaki E
- Agam G
- Agarwal A
- Aggarwal BB
- Agnello M
- Agostinis P
- Agrewala JN
- Agrotis A
- Aguilar PV
- Ahmad ST
- Ahmed ZM
- Ahumada-Castro U
- Aits S
- Aizawa S
- Akkoc Y
- Akoumianaki T
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- Al-Abd AM
- Al-Akra L
- Al-Gharaibeh A
- Alaoui-Jamali MA
- Alberti S
- Alcocer-Gómez E
- Alessandri C
- Ali M
- Alim Al-Bari MA
- Aliwaini S
- Alizadeh J
- Almacellas E
- Almasan A
- Alonso A
- Alonso GD
- Altan-Bonnet N
- Altieri DC
- Alves da Costa C
- Alves S
- Alzaharna MM
- Amadio M
- Amantini C
- Amaral C
- Ambrosio S
- Amer AO
- Ammanathan V
- An Z
- Andersen SU
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- Angelini S
- Ann D
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- Arévalo M-A
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- Aschner M
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- Atanasov AG
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- Zhu B
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- Zhu H
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- Zhu W-G
- Zhu Y
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- Zhuang H
- Zhuang X
- Zientara-Rytter K
- Zimmermann CM
- Ziviani E
- Zoladek T
- Zong W-X
- Zorov DB
- Zorzano A
- Zou W
- Zou Z
- Zou Z
- Zuryn S
- Zwerschke W
- Álvarez ÉMC
- Ávalos Y
- Önal G
- Üstün S
- Čolić M
- Đokić J
- Žerovnik E
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2021
- Field of study
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field
Repositioning of the global epicentre of non-optimal cholesterol
- Author
- Aadahl Mette
- Abarca-Gómez Leandra
- Abu-Rmeileh Niveen M.
- Acosta-Cazares Benjamin
- Adams Robert J.
- Aekplakorn Wichai
- Agdeppa Imelda A.
- Aghazadeh-Attari Javad
- Aguilar-Salinas Carlos A.
- Agyemang Charles
- Ahluwalia Tarunveer S.
- Ahmad Noor Ani
- Ahmadi Ali
- Ahmadi Naser
- Ahmed Soheir H.
- Ahrens Wolfgang
- Ajlouni Kamel
- al-Safi Ismail Aziz
- Alarouj Monira
- AlBuhairan Fadia
- AlDhukair Shahla
- Ali Mohamed M.
- Alkandari Abdullah
- Alkerwi Ala’a
- Aly Eman
- Amarapurkar Deepak N.
- Amouyel Philippe
- Andersen Lars Bo
- Anderssen Sigmund A.
- Anjana Ranjit Mohan
- Ansari-Moghaddam Alireza
- Aounallah-Skhiri Hajer
- Araújo Joana
- Ariansen Inger
- Aris Tahir
- Arku Raphael E.
- Arlappa Nimmathota
- Aryal Krishna K.
- Asghari Golaleh
- Aspelund Thor
- Assunção Maria Cecília F.
- Auvinen Juha
- Avdicová Mária
- Azevedo Ana
- Azizi Fereidoun
- Azmin Mehrdad
- Balakrishna Nagalla
- Bamoshmoosh Mohamed
- Banach Maciej
- Bandosz Piotr
- Banegas José R.
- Bao Tran Quoc
- Barbagallo Carlo M.
- Barceló Alberto
- Barkat Amina
- Bata Iqbal
- Batieha Anwar M.
- Batyrbek Assembekov
- Baur Louise A.
- Beaglehole Robert
- Bebakar Wan Mohamad Wan
- Belavendra Antonisamy
- Ben Romdhane Habiba
- Benet Mikhail
- Benn Marianne
- Bennett James E.
- Berkinbayev Salim
- Bernabe-Ortiz Antonio
- Bernotiene Gailute
- Bettiol Heloisa
- Bhargava Santosh K.
- Bi Yufang
- Bienek Asako
- Bikbov Mukharram
- Bista Bihungum
- Bixby Honor
- Bjerregaard Peter
- Bjertness Espen
- Bjertness Marius B.
- Björkelund Cecilia
- Bloch Katia V.
- Blokstra Anneke
- Bo Simona
- Boehm Bernhard O.
- Boggia Jose G.
- Boissonnet Carlos P.
- Bonaccio Marialaura
- Bongard Vanina
- Borchini Rossana
- Borghs Herman
- Bovet Pascal
- Brajkovich Imperia
- Breckenkamp Juergen
- Brenner Hermann
- Brewster Lizzy M.
- Bruno Graziella
- Bugge Anna
- Busch Markus A.
- Cacciottolo Joseph
- Can Günay
- Capanzana Mario V.
- Capuano Eduardo
- Capuano Vincenzo
- Cardoso Viviane C.
- Carrillo-Larco Rodrigo M.
- Carvalho Joana
- Casanueva Felipe F.
- Censi Laura
- Chadjigeorgiou Charalambos A.
- Chamukuttan Snehalatha
- Chaturvedi Nish
- Chen Chien-Jen
- Chen Fangfang
- Chen Shuohua
- Cheng Ching-Yu
- Cheraghian Bahman
- Chetrit Angela
- Chiou Shu-Ti
- Chirlaque María-Dolores
- Cho Belong
- Cho Yumi
- Chudek Jerzy
- Cifkova Renata
- Cisneros Julio Zuñiga
- Claessens Frank
- Clarke Janine
- Clays Els
- Concin Hans
- Confortin Susana C.
- Cooper Cyrus
- Costanzo Simona
- Cottel Dominique
- Cowan Melanie J.
- Cowell Chris
- Crujeiras Ana B.
- Csilla Semánová
- Cui Liufu
- Cureau Felipe V.
- Cândido Ana Paula C.
- Dallongeville Jean
- Damasceno Albertino
- Danaei Goodarz
- Dankner Rachel
- Dantoft Thomas M.
- Dauchet Luc
- Davletov Kairat
- De Backer Guy
- De Bacquer Dirk
- de Gaetano Giovanni
- De Henauw Stefaan
- de León Antonio Cabrera
- de Oliveira Paula Duarte
- De Ridder David
- De Smedt Delphine
- Deepa Mohan
- Deev Alexander D.
- Dehghan Abbas
- del Cristo Rodriguez-Perez María
- Delisle Hélène
- Dennison Elaine
- Deschamps Valérie
- Dhana Klodian
- Dhimal Meghnath
- Di Castelnuovo Augusto F.
- Di Cesare Mariachiara
- Dika Zivka
- Djalalinia Shirin
- do Carmo Franco Maria
- Dobson Annette J.
- Donfrancesco Chiara
- Donoso Silvana P.
- Dorobantu Maria
- Dragano Nico
- Drygas Wojciech
- Du Yong
- Duante Charmaine A.
- Duda Rosemary B.
- Dzerve Vilnis
- Dziankowska-Zaborszczyk Elzbieta
- Döring Angela
- D’Arrigo Graziella
- d’Orsi Eleonora
- Eddie Ricky
- Eftekhar Ebrahim
- Eggertsen Robert
- Eghtesad Sareh
- Eiben Gabriele
- Ekelund Ulf
- El Ati Jalila
- Eldemire-Shearer Denise
- Eliasen Marie
- Elosua Roberto
- Erasmus Rajiv T.
- Erbel Raimund
- Erem Cihangir
- Eriksen Louise
- Eriksson Johan G.
- Escobedo-de la Peña Jorge
- Eslami Saeid
- Esmaeili Ali
- Evans Alun
- Ezzati Majid
- Faeh David
- Fall Caroline H.
- Faramarzi Elnaz
- Farjam Mojtaba
- Farzadfar Farshad
- Fattahi Mohammad Reza
- Felix-Redondo Francisco J.
- Ferguson Trevor S.
- Fernández-Bergés Daniel
- Ferrante Daniel
- Ferrari Marika
- Ferreccio Catterina
- Ferrieres Jean
- Foo Leng Huat
- Forslund Ann-Sofie
- Forsner Maria
- Fouad Heba M.
- Francis Damian K.
- Franco Oscar H.
- Frontera Guillermo
- Fujita Yuki
- Fumihiko Matsuda
- Furusawa Takuro
- Föger Bernhard
- Gaciong Zbigniew
- Galvano Fabio
- Gao Jingli
- Garcia-de-la-Hera Manoli
- Garnett Sarah P.
- Gaspoz Jean-Michel
- Gasull Magda
- Gazzinelli Andrea
- Geleijnse Johanna M.
- Ghanbari Ali
- Ghasemi Erfan
- Gheorghe-Fronea Oana-Florentina
- Ghimire Anup
- Giampaoli Simona
- Gianfagna Francesco
- Gill Tiffany K.
- Giovannelli Jonathan
- Gironella Glen
- Giwercman Aleksander
- Goltzman David
- Gonzalez Angel R.
- Gonzalez-Chica David A.
- Gonzalez-Gross Marcela
- González-Rivas Juan P.
- González-Villalpando Clicerio
- González-Villalpando María-Elena
- Gonçalves Helen
- Gottrand Frederic
- Graff-Iversen Sidsel
- Grafnetter Dušan
- Gregg Edward W.
- Gregor Ronald D.
- Grodzicki Tomasz
- Grosso Giuseppe
- Gruden Gabriella
- Grøntved Anders
- Gu Dongfeng
- Guallar-Castillón Pilar
- Guan Ong Peng
- Gudmundsson Elias F.
- Gudnason Vilmundur
- Guerrero Ramiro
- Guessous Idris
- Gulayin Pablo
- Gunnlaugsdottir Johanna
- Gupta Rajeev
- Gutierrez Laura
- Gutzwiller Felix
- Ha Seongjun
- Hadaegh Farzad
- Haghshenas Rosa
- Hakimi Hamid
- Hambleton Ian R.
- Hamzeh Behrooz
- Hantunen Sari
- Hashemi-Shahri Seyed Mohammad
- Hata Jun
- Haugsgjerd Teresa
- Hayes Alison J.
- He Jiang
- He Yuna
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- Hwalla Nahla
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- Kamaruddin Nor Azmi
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- Kazakbaeva Gyulli
- Keil Ulrich
- Keinänen-Kiukaanniemi Sirkka
- Kelishadi Roya
- Kengne Andre Pascal
- Keramati Maryam
- Kerimkulova Alina
- Kersting Mathilde
- Khader Yousef Saleh
- Khalili Davood
- Khang Young-Ho
- Khateeb Mohammad
- Kheradmand Motahareh
- Khosravi Alireza
- Kiechl Stefan
- Kiechl-Kohlendorfer Ursula
- Killewo Japhet
- Kim Hyeon Chang
- Kim Jeongseon
- Kim Yeon-Yong
- Klumbiene Jurate
- Knoflach Michael
- Ko Stephanie
- Kohler Hans-Peter
- Kohler Iliana V.
- Kolle Elin
- Kolsteren Patrick
- Korpelainen Raija
- Korrovits Paul
- Kos Jelena
- Koskinen Seppo
- Kouda Katsuyasu
- Kowlessur Sudhir
- Kratzer Wolfgang
- Kriemler Susi
- Kristensen Peter Lund
- Krokstad Steiner
- Kromhout Daan
- Kujala Urho M.
- Kumar Rachakulla Hari
- Kurjata Pawel
- Kuulasmaa Kari
- Kyobutungi Catherine
- König Jürgen
- Laamiri Fatima Zahra
- Laatikainen Tiina
- Lachat Carl
- Laid Youcef
- Lam Tai Hing
- Lambrinou Christina-Paulina
- Lanska Vera
- Lappas Georg
- Larijani Bagher
- Latt Tint Swe
- Laugsand Lars E.
- Laxmaiah Avula
- Lazo-Porras Maria
- Lee Jeannette
- Lee Jeonghee
- Lehmann Nils
- Lehtimäki Terho
- Levitt Naomi S.
- Li Yanping
- Lilly Christa L.
- Lim Wei-Yen
- Lima-Costa M. Fernanda
- Lin Hsien-Ho
- Lin Xu
- Lin Yi-Ting
- Lind Lars
- Linneberg Allan
- Lissner Lauren
- Liu Jing
- Loit Helle-Mai
- Lopez Tania
- Lopez-Garcia Esther
- Lotufo Paulo A.
- Lozano José Eugenio
- Luksiene Dalia
- Lundqvist Annamari
- Lundqvist Robert
- Lunet Nuno
- Ma Guansheng
- Machado-Coelho George L. L.
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- Machi Suka
- Madar Ahmed A.
- Maggi Stefania
- Magliano Dianna J.
- Magriplis Emmanuella
- Mahasampath Gowri
- Maire Bernard
- Makdisse Marcia
- Malekzadeh Fatemeh
- Malekzadeh Reza
- Manios Yannis
- Mann Jim I.
- Mansour-Ghanaei Fariborz
- Manzato Enzo
- Margozzini Paula
- Marques-Vidal Pedro
- Martinez Andrea Rodriguez
- Martorell Reynaldo
- Mascarenhas Luis P.
- Mathiesen Ellisiv B.
- Mathur Prashant
- Matsha Tandi E.
- Mavrogianni Christina
- McFarlane Shelly R.
- McGarvey Stephen T.
- McLachlan Stela
- McLean Rachael M.
- McLean Scott B.
- McNulty Breige A.
- Mediene-Benchekor Sounnia
- Mehdipour Parinaz
- Mehlig Kirsten
- Mehrparvar Amir Houshang
- Meirhaeghe Aline
- Meisinger Christa
- Menezes Ana Maria B.
- Menon Geetha R.
- Merat Shahin
- Mereke Alibek
- Meshram Indrapal I.
- Metcalf Patricia
- Meyer Haakon E.
- Mi Jie
- Michels Nathalie
- Miller Jody C.
- Minderico Cláudia S.
- Mini G. K.
- Miquel Juan Francisco
- Miranda J. Jaime
- Mirjalili Mohammad Reza
- Mirrakhimov Erkin
- Modesti Pietro A.
- Moghaddam Sahar Saeedi
- Mohajer Bahram
- Mohamed Mostafa K.
- Mohammad Kazem
- Mohammadi Zahra
- Mohammadifard Noushin
- Mohammadpourhodki Reza
- Mohamud Wan Nazaimoon Wan
- Mohan Viswanathan
- Mohanna Salim
- Mohebbi Iraj
- Mohebi Farnam
- Moitry Marie
- Molnár Dénes
- Momenan Amirabbas
- Mondo Charles K.
- Monterrubio-Flores Eric
- Moosazadeh Mahmood
- Morejon Alain
- Moreno Luis A.
- Morgan Karen
- Morin Suzanne N.
- Moschonis George
- Mossakowska Malgorzata
- Mostafa Aya
- Mota Jorge
- Motlagh Mohammad Esmaeel
- Motta Jorge
- Msyamboza Kelias P.
- Muiesan Maria L.
- Mursu Jaakko
- Mustafa Norlaila
- Møllehave Line T.
- Møller Niels C.
- Müller-Nurasyid Martina
- Nabipour Iraj
- Naderimagham Shohreh
- Nagel Gabriele
- Naidu Balkish M.
- Najafi Farid
- Nakamura Harunobu
- Nang Ei Ei K.
- Nangia Vinay B.
- Nauck Matthias
- NCD Risk Factor Collaboration (NCD-RisC)
- Neal William A.
- Nejatizadeh Azim
- Nenko Ilona
- Nervi Flavio
- Nguyen Nguyen D.
- Nguyen Quang Ngoc
- Nieto-Martínez Ramfis E.
- Nihal Thomas
- Niiranen Teemu J.
- Ning Guang
- Ninomiya Toshiharu
- Noale Marianna
- Noboa Oscar A.
- Nordestgaard Børge G.
- Noto Davide
- Nsour Mohannad Al
- Nuhoğlu Irfan
- Námešná Jana
- Ochoa-Avilés Angélica M.
- Oh Kyungwon
- Ohtsuka Ryutaro
- Olafsson Örn
- Oliveira Isabel O.
- Olié Valérie
- Omar Mohd Azahadi
- Onat Altan
- Ong Sok King
- Ordunez Pedro
- Ornelas Rui
- Ortiz Pedro J.
- Osmond Clive
- Ostojic Sergej M.
- Ostovar Afshin
- Otero Johanna A.
- Owusu-Dabo Ellis
- O’Neill Terence W.
- O’Reilly Dermot
- Paccaud Fred Michel
- Paciorek Christopher J.
- Pahomova Elena
- Pajak Andrzej
- Palmieri Luigi
- Pan Wen-Harn
- Panda-Jonas Songhomitra
- Panza Francesco
- Parnell Winsome R.
- Patel Nikhil D.
- Peer Nasheeta
- Peixoto Sergio Viana
- Peltonen Markku
- Pereira Alexandre C.
- Peters Annette
- Petersmann Astrid
- Petkeviciene Janina
- Peykari Niloofar
- Pham Son Thai
- Pichardo Rafael N.
- Pigeot Iris
- Pilav Aida
- Pilotto Lorenza
- Piwonska Aleksandra
- Pizarro Andreia N.
- Plans-Rubió Pedro
- Plata Silvia
- Pohlabeln Hermann
- Porta Miquel
- Portegies Marileen L. P.
- Poudyal Anil
- Pourfarzi Farhad
- Poustchi Hossein
- Pradeepa Rajendra
- Price Jacqueline F.
- Providencia Rui
- Puder Jardena J.
- Puhakka Soile E.
- Punab Margus
- Qorbani Mostafa
- Radisauskas Ricardas
- Rahim Hanan Abdul
- Rahimikazerooni Salar
- Raitakari Olli
- Ramachandran Ambady
- Ramos Elisabete
- Ramos Rafel
- Rampal Lekhraj
- Rampal Sanjay
- Rao Kodavanti Mallikharjuna
- Rao Sudha Ramachandra
- Redon Josep
- Reganit Paul Ferdinand M.
- Revilla Luis
- Rezaianzadeh Abbas
- Ribeiro Robespierre
- Richter Adrian
- Rigo Fernando
- Riley Leanne M.
- Rinke de Wit Tobias F.
- Rodríguez-Artalejo Fernando
- Rodríguez-Villamizar Laura A.
- Roggenbuck Ulla
- Rojas-Martinez Rosalba
- Romaguera Dora
- Romeo Elisabetta L.
- Rosengren Annika
- Roy Joel G. R.
- Rubinstein Adolfo
- Ruidavets Jean-Bernard
- Ruiz-Betancourt Blanca Sandra
- Russo Paola
- Rust Petra
- Rutkowski Marcin
- Sabanayagam Charumathi
- Sachdev Harshpal S.
- Sadjadi Alireza
- Safarpour Ali Reza
- Safiri Saeid
- Saidi Olfa
- Saki Nader
- Salanave Benoit
- Salmerón Diego
- Salomaa Veikko
- Salonen Jukka T.
- Salvetti Massimo
- Sans Susana
- Santaliestra-Pasías Alba M.
- Santero Marilina
- Santos Diana A.
- Santos Maria Paula
- Santos Rute
- Saramies Jouko L.
- Sardinha Luis B.
- Sarrafzadegan Nizal
- Saum Kai-Uwe
- Savin Stefan
- Savva Savvas C.
- Sawada Norie
- Sbaraini Mariana
- Scazufca Marcia
- Schaan Beatriz D.
- Schargrodsky Herman
- Scheidt-Nave Christa
- Schienkiewitz Anja
- Schipf Sabine
- Schmidt Carsten O.
- Schramm Sara
- Schöttker Ben
- Sebert Sylvain
- Sein Aye Aye
- Sen Abhijit
- Sepanlou Sadaf G.
- Servais Jennifer
- Shakeri Ramin
- Shalnova Svetlana A.
- Shamah-Levy Teresa
- Sharafkhah Maryam
- Sharma Sanjib K.
- Shaw Jonathan E.
- Shayanrad Amaneh
- Shi Zumin
- Shibuya Kenji
- Shimizu-Furusawa Hana
- Shin Dong Wook
- Shin Youchan
- Shirani Majid
- Shiri Rahman
- Shrestha Namuna
- Si-Ramlee Khairil
- Siani Alfonso
- Siantar Rosalynn
- Sibai Abla M.
- Silva Diego Augusto Santos
- Simon Mary
- Simons Judith
- Simons Leon A.
- Sjöström Michael
- Skaaby Tea
- Slowikowska-Hilczer Jolanta
- Slusarczyk Przemyslaw
- Smeeth Liam
- Snijder Marieke B.
- Soemantri Agustinus
- Sofat Reecha
- Solfrizzi Vincenzo
- Somi Mohammad Hossein
- Sonestedt Emily
- Sophiea Marisa K.
- Soumaré Aïcha
- Sozmen Kaan
- Sparrenberger Karen
- Staessen Jan A.
- Stathopoulou Maria G.
- Stavreski Bill
- Steene-Johannessen Jostein
- Stehle Peter
- Stein Aryeh D.
- Stessman Jochanan
- Stevanović Ranko
- Stevens Gretchen A.
- Stieber Jutta
- Stokwiszewski Jakub
- Stronks Karien
- Strufaldi Maria Wany
- Stöckl Doris
- Sun Chien-An
- Sundström Johan
- Suriyawongpaisal Paibul
- Suárez-Medina Ramón
- Sy Rody G.
- Sylva René Charles
- Szklo Moyses
- Sánchez-Abanto Jose
- Söderberg Stefan
- Sørensen Thorkild I. A.
- Taddei Cristina
- Tai E. Shyong
- Tamosiunas Abdonas
- Tan Eng Joo
- Tarawneh Mohammed Rasoul
- Tarqui-Mamani Carolina B.
- Taylor Anne
- Taylor Julie
- Tell Grethe S.
- Tello Tania
- Thankappan K. R.
- Thijs Lutgarde
- Thuesen Betina H.
- Toft Ulla
- Tolonen Hanna K.
- Tolstrup Janne S.
- Topbas Murat
- Topór-Madry Roman
- Tormo María José
- Tornaritis Michael J.
- Torrent Maties
- Torres-Collado Laura
- Traissac Pierre
- Trinh Oanh T. H.
- Truthmann Julia
- Tsugane Shoichiro
- Tulloch-Reid Marshall K.
- Tuomainen Tomi-Pekka
- Tuomilehto Jaakko
- Tybjaerg-Hansen Anne
- Tzourio Christophe
- Ueda Peter
- Ugel Eunice
- Ulmer Hanno
- Unal Belgin
- Uusitalo Hannu M. T.
- Valdivia Gonzalo
- Valvi Damaskini
- van Dam Rob M.
- van der Schouw Yvonne T.
- Van Herck Koen
- Van Minh Hoang
- van Rossem Lenie
- Van Schoor Natasja M.
- van Valkengoed Irene G. M.
- Vanderschueren Dirk
- Vanuzzo Diego
- Varbo Anette
- Varona-Pérez Patricia
- Vasan Senthil K.
- Vatten Lars
- Vega Tomas
- Veidebaum Toomas
- Velasquez-Melendez Gustavo
- Venero-Fernández Silvia J.
- Veronesi Giovanni
- Verschuren W. M. Monique
- Victora Cesar G.
- Vidiawati Dhanasari
- Viet Lucie
- Villalpando Salvador
- Vioque Jesus
- Virtanen Jyrki K.
- Visvikis-Siest Sophie
- Viswanathan Bharathi
- Vlasoff Tiina
- Vollenweider Peter
- Voortman Trudy
- Voutilainen Ari
- Vrkic Tajana Zeljkovic
- Wade Alisha N.
- Wagner Aline
- Walton Janette
- Wang Ming-Dong
- Wang Ningli
- Wang Qian
- Wang Ya Xing
- Wang Ying-Wei
- Wannamethee S. Goya
- Wedderkopp Niels
- Wei Wenbin
- Whincup Peter H.
- Widhalm Kurt
- Widyahening Indah S.
- Wiecek Andrzej
- Wijga Alet H.
- Wilks Rainford J.
- Willeit Johann
- Willeit Peter
- Wilsgaard Tom
- Wojtyniak Bogdan
- Wong Andrew
- Wong Norazizah Ibrahim
- Wong Tien Yin
- Wong-McClure Roy A.
- Woo Jean
- Woodward Mark
- Wu Frederick C.
- Wu Shouling
- Xu Haiquan
- Xu Liang
- Yan Weili
- Yang Xiaoguang
- Yasuharu Tabara
- Ye Xingwang
- Yeow Toh Peng
- Yiallouros Panayiotis K.
- Yoosefi Moein
- Yoshihara Akihiro
- You San-Lin
- Younger-Coleman Novie O.
- Yusoff Ahmad Faudzi
- Yusoff Muhammad Fadhli Mohd
- Zainuddin Ahmad A.
- Zakavi Seyed Rasoul
- Zali Mohammad Reza
- Zamani Farhad
- Zambon Sabina
- Zampelas Antonis
- Zaw Ko Ko
- Zdrojewski Tomasz
- Zhang Zhen-Yu
- Zhao Dong
- Zhao Wenhua
- Zhen Shiqi
- Zheng Yingfeng
- Zholdin Bekbolat
- Zhou Bin
- Zhussupov Baurzhan
- Zoghlami Nada
- Publication venue
- Publication date
- 01/01/2020
- Field of study
High blood cholesterol is typically considered a feature of wealthy western countries(1,2). However, dietary and behavioural determinants of blood cholesterol are changing rapidly throughout the world(3) and countries are using lipid-lowering medications at varying rates. These changes can have distinct effects on the levels of high-density lipoprotein (HDL) cholesterol and non-HDL cholesterol, which have different effects on human health(4,5). However, the trends of HDL and non-HDL cholesterol levels over time have not been previously reported in a global analysis. Here we pooled 1,127 population-based studies that measured blood lipids in 102.6 million individuals aged 18 years and older to estimate trends from 1980 to 2018 in mean total, non-HDL and HDL cholesterol levels for 200 countries. Globally, there was little change in total or non-HDL cholesterol from 1980 to 2018. This was a net effect of increases in low- and middle-income countries, especially in east and southeast Asia, and decreases in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe. As a result, countries with the highest level of non-HDL cholesterol-which is a marker of cardiovascular riskchanged from those in western Europe such as Belgium, Finland, Greenland, Iceland, Norway, Sweden, Switzerland and Malta in 1980 to those in Asia and the Pacific, such as Tokelau, Malaysia, The Philippines and Thailand. In 2017, high non-HDL cholesterol was responsible for an estimated 3.9 million (95% credible interval 3.7 million-4.2 million) worldwide deaths, half of which occurred in east, southeast and south Asia. The global repositioning of lipid-related risk, with non-optimal cholesterol shifting from a distinct feature of high-income countries in northwestern Europe, north America and Australasia to one that affects countries in east and southeast Asia and Oceania should motivate the use of population-based policies and personal interventions to improve nutrition and enhance access to treatment throughout the world.Peer reviewe
Rising rural body-mass index is the main driver of the global obesity epidemic in adults
- Author
- Abarca-Gomez Leandra
- Abdeen Ziad A.
- Abdrakhmanova Shynar
- Abu-Rmeileh Niveen M.
- Acosta-Cazares Benjamin
- Adams Robert J.
- Aekplakorn Wichai
- Afsana Kaosar
- Agdeppa Imelda A.
- Aguilar-Salinas Carlos A.
- Agyemang Charles
- Ahmad Mohamad Hasnan
- Ahmad Noor Ani
- Ahmadi Naser
- Ahmadvand Alireza
- Ahrens Wolfgang
- Ajlouni Kamel
- Al Nsour Mohannad
- Al-Hazzaa Hazzaa M.
- Al-Othman Amani Rashed
- Al-Raddadi Rajaa
- AlBuhairan Fadia
- AlDhukair Shahla
- Ali Mohamed M.
- Ali Osman
- Alkerwi Ala'a
- Alvarez-Pedrerol Mar
- Aly Eman
- Amarapurkar Deepak N.
- Amouyel Philippe
- Amuzu Antoinette
- Anderssen Sigmund A.
- Angquist Lars H.
- Anjana Ranjit Mohan
- Ansari-Moghaddam Alireza
- Anselmo Olinto Maria Teresa
- Aounallah-Skhiri Hajer
- Araujo Joana
- Ariansen Inger
- Aris Tahir
- Arku Raphael E.
- Arlappa Nimmathota
- Aryal Krishna K.
- Aspelund Thor
- Assah Felix K.
- Assuncao Maria Cecilia F.
- Aung May Soe
- Auvinen Juha
- Avdicova Maria
- Azevedo Ana
- Azizi Fereidoun
- Azmin Mehrdad
- Babu Bontha V.
- Baharudin Azli
- Bahijri Suhad
- Baker Jennifer L.
- Balakrishna Nagalla
- Bamoshmoosh Mohamed
- Banach Maciej
- Bandosz Piotr
- Banegas Jose R.
- Barbagallo Carlo M.
- Barcelo Alberto
- Barkat Amina
- Barros Aluisio J. D.
- Barros Mauro V. G.
- Bata Iqbal
- Batieha Anwar M.
- Batista Rosangela L.
- Battakova Zhamilya
- Batyrbek Assembekov
- Baur Louise A.
- Beaglehole Robert
- Bebakar Wan Mohamad Wan
- Bel-Serrat Silvia
- Ben Romdhane Habiba
- Benedics Judith
- Benet Mikhail
- Bennett James E.
- Bentham James
- Berkinbayev Salim
- Bernabe-Ortiz Antonio
- Bernotiene Gailute
- Bettiol Heloisa
- Bhagyalaxmi Aroor
- Bharadwaj Sumit
- Bhargava Santosh K.
- Bhutta Zulfiqar A.
- Bi Hongsheng
- Bi Yufang
- Biehl Anna
- Bikbov Mukharram
- Bista Bihungum
- Bixby Honor
- Bjelica Dusko J.
- Bjerregaard Peter
- Bjertness Espen
- Bjertness Marius B.
- Bjorkelund Cecilia
- Blokstra Anneke
- Bo Lars
- Bo Simona
- Bobak Martin
- Boddy Lynne M.
- Boehm Bernhard O.
- Boeing Heiner
- Boggia Jose G.
- Boissonnet Carlos P.
- Bonaccio Marialaura
- Bongard Vanina
- Bopp Matthias
- Borchini Rossana
- Borghs Herman
- Bovet Pascal
- Braeckevelt Lien
- Braeckman Lutgart
- Bragt Marjolijn C. E.
- Brajkovich Imperia
- Branca Francesco
- Braunerova Radka Taxova
- Breckenkamp Jürgen
- Breda Joao
- Brenner Hermann
- Brewster Lizzy M.
- Brian Garry R.
- Brinduse Lacramioara
- Bruno Graziella
- Bueno-de-Mesquita H. Bas
- Bugge Anna
- Buoncristiano Marta
- Burazeri Genc
- Burns Con
- Cabrera de Leon Antonio
- Cacciottolo Joseph
- Cai Hui
- Cama Tilema
- Cameron Christine
- Camolas Jose
- Can Gamze
- Can Gunay
- Candido Ana Paula C.
- Canete Felicia
- Capanzana Mario V.
- Capuano Eduardo
- Capuano Vincenzo
- Cardoso Viviane C.
- Carlsson Axel C.
- Carmuega Esteban
- Carrillo-Larco Rodrigo M.
- Carvalho Maria J.
- Casanueva Felipe F.
- Casas Juan-Pablo
- Caserta Carmelo A.
- Celikcan Ertugrul
- Censi Laura
- Cesar Juraci A.
- Chamukuttan Snehalatha
- Chan Angelique W.
- Chan Queenie
- Chaturvedi Himanshu K.
- Chaturvedi Nishi
- Chen Chien-Jen
- Chen Fangfang
- Chen Huashuai
- Chen Shuohua
- Chen Zhengming
- Cheng Ching-Yu
- Cheng Yiling J.
- Chetrit Angela
- Chikova-Iscener Ekaterina
- Chinh Nguyen Huu Chinh Nguyen Huu
- Chiolero Arnaud
- Chiou Shu-Ti
- Chirita-Emandi Adela
- Chirlaque Maria-Dolores
- Cho Belong
- Cho Yumi
- Christensen Kaare
- Christofaro Diego G.
- Chudek Jerzy
- Cifkova Renata
- Cilia Michelle
- Cinteza Eliza
- Claessens Frank
- Clarke Janine
- Clays Els
- Concin Hans
- Confortin Susana C.
- Cooper Cyrus
- Coppinger Tara C.
- Costanzo Simona
- Cottel Dominique
- Cowan Melanie J.
- Cowell Chris
- Craig Cora L.
- Crampin Amelia C.
- Crujeiras Ana B.
- Cruz Juan J.
- Cucu Alexandra
- Cui Liufu
- D'Arrigo Graziella
- d'Orsi Eleonora
- Dallongeville Jean
- Damasceno Albertino
- Damsgaard Camilla T.
- Danaei Goodarz
- Dankner Rachel
- Dantoft Thomas M.
- Dasgupta Parasmani
- Dastgiri Saeed
- Dauchet Luc
- Davletov Kairat
- De Backer Guy
- De Bacquer Dirk
- De Curtis Amalia
- de Gaetano Giovanni
- De Henauw Stefaan
- de Oliveira Paula Duarte
- De Ridder Karin
- de Rooij Susanne R.
- De Smedt Delphine
- de Wit Tobias F. Rinke
- Deepa Mohan
- Deev Alexander D.
- Dehghan Abbas
- del Cristo Rodriguez-Perez Maria
- Delisle Helene
- Delpeuch Francis
- Dennison Elaine
- Deschamps Valerie
- Dhana Klodian
- Dhimal Meghnath
- Di Castelnuovo Augusto F.
- Di Cesare Mariachiara
- Dias-da-Costa Juvenal Soares
- Diaz Alejandro
- Dika Zivka
- Djalalinia Shirin
- Do Ha T. P.
- Dobson Annette J.
- Doering Angela
- Donati Maria Benedetta
- Donfrancesco Chiara
- Donoso Silvana P.
- Dorobantu Maria
- Dorosty Ahmad Reza
- Doua Kouamelan
- Drygas Wojciech
- Duan Jia Li
- Duante Charmaine A.
- Duda Rosemary B.
- Duleva Vesselka
- Dulskiene Virginija
- Dumith Samuel C.
- Dzerve Vilnis
- Dziankowska-Zaborszczyk Elzbieta
- Eddie Ricky
- Egbagbe Eruke E.
- Eggertsen Robert
- Eiben Gabriele
- Ekelund Ulf
- El Ati Jalila
- Eldemire-Shearer Denise
- Eliasen Marie
- Elliott Paul
- Engle-Stone Reina
- Erasmus Rajiv T.
- Erem Cihangir
- Eriksen Louise
- Eriksson Johan G.
- Escobedo-de la Pena Jorge
- Evans Alun
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- Weghuber Daniel
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- Wilks Rainford J.
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- Wong Norazizah Ibrahim
- Wong Tien Yin
- Wong-McClure Roy A.
- Woo Jean
- Woodward Mark
- Wu Frederick C.
- Wu Jianfeng
- Wu Shouling
- Xu Haiquan
- Xu Liang
- Yamborisut Uruwan
- Yan Weili
- Yang Ling
- Yang Xiaoguang
- Yang Yang
- Yardim Nazan
- Yaseri Mehdi
- Ye Xingwang
- Yiallouros Panayiotis K.
- Yngve Agneta
- Yoosefi Moein
- Yoshihara Akihiro
- You Qi Sheng
- You San-Lin
- Younger-Coleman Novie O.
- Yusof Safiah Md
- Yusoff Ahmad Faudzi
- Yusoff Muhammad Fadhli Mohd
- Zaccagni Luciana
- Zafiropulos Vassilis
- Zainuddin Ahmad A.
- Zamani Farhad
- Zambon Sabina
- Zampelas Antonis
- Zamrazilova Hana
- Zapata Maria Elisa
- Zaw Ko Ko
- Zdrojewski Tomasz
- Zeng Yi
- Zhao Dong
- Zhao Wenhua
- Zheng Wei
- Zheng Yingfeng
- Zholdin Bekbolat
- Zhou Bin
- Zhou Maigeng
- Zhu Dan
- Zhussupov Baurzhan
- Zimmermann Esther
- Zuniga Cisneros Julio
- Publication venue
- Publication date
- 01/01/2019
- Field of study
Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities(.)(1,2) This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity(3-6). Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean BMI segregated by place of residence (a rural or urban area) from 1985 to 2017. We show that, contrary to the dominant paradigm, more than 55% of the global rise in mean BMI from 1985 to 2017-and more than 80% in some low- and middle-income regions-was due to increases in BMI in rural areas. This large contribution stems from the fact that, with the exception of women in sub-Saharan Africa, BMI is increasing at the same rate or faster in rural areas than in cities in low- and middle-income regions. These trends have in turn resulted in a closing-and in some countries reversal-of the gap in BMI between urban and rural areas in low- and middle-income countries, especially for women. In high-income and industrialized countries, we noted a persistently higher rural BMI, especially for women. There is an urgent need for an integrated approach to rural nutrition that enhances financial and physical access to healthy foods, to avoid replacing the rural undernutrition disadvantage in poor countries with a more general malnutrition disadvantage that entails excessive consumption of low-quality calories.Peer reviewe
Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults
- Author
- Abbas Rezaianzadeh
- Abdonas Tamosiunas
- Abdul Basit
- Abdul Hamid Zargar
- Abdullah Alkandari
- Abdullatif Husseini
- Abhijit Sen
- Abla M Sibai
- Abu Am Hanif
- Adela Chirita-Emandi
- Adelheid Weber
- Adetoyeje Y Oyeyemi
- Adewale L Oyeyemi
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- Vayia Rarra
- Vedrana Sember
- Veikko Salomaa
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- Vera Musil
- Veronica Mocanu
- Vesna Juresa
- Vesselka L Duleva
- Victor M Herrera
- Victor Matsudo
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- Vijaya Lingam
- Viktoria Anna Kovacs
- Viktoriya Furdela
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- Vilmundur Gudnason
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- Violeta Iotova
- Virginija Dulskiene
- Virgílio V Ramires
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- Viswanathan Mohan
- Viviana Guajardo
- Viviane C Cardoso
- Vladimir Kutsenko
- Wafaie W Fawzi
- Wan Mohamad Wan Bebakar
- Wan Nazaimoon Wan Mohamud
- Wei Zheng
- Wei-Cheng Lo
- Wei-Yen Lim
- Weili Yan
- Wen-Harn Pan
- Wenbin Wei
- Wendy Van Lippevelde
- Wenhua Zhao
- Wichai Aekplakorn
- Willem A Hanekom
- William A Neal
- William R Tebar
- Wilma M Hopman
- Winsome R Parnell
- Wm Monique Verschuren
- Wojciech Drygas
- Wojciech Rusek
- Wolfgang Ahrens
- Wolfgang Kratzer
- Xenophon Theodoridis
- Xiangjun Wang
- Xiaoguang Yang
- Xiaotian Liu
- Ximena Berrios Carrasola
- Xinyi Gwee
- Xiu-Hua Guo
- Xu Lin
- Xu Ma
- Xueling Sim
- Xun Tang
- Ya Xing Wang
- Yadlapalli S Kusuma
- Yajaira Briceño
- Yang Yang
- Yanhui Dong
- Yanina Zocalo
- Yanitsa V Zhecheva
- Yannis Manios
- Yanping Li
- Yemane Berhane
- Yeunsook Rho
- Yeva Movsesyan
- Yi Song
- Yi Zeng
- Yih Chung Tham
- Yiling J Cheng
- Yin Guo
- Ying-Wei Wang
- Yingfeng Zheng
- Yn-Tz Sung
- Yong Tao
- Yonghua Hu
- Yosef Farzi
- Yoto Yotov
- Youcef Laid
- Young-Ho Khang
- Yousef Saleh Khader
- Yu-Ling Yu
- Yuan He
- Yufang Bi
- Yuki Fujita
- Yulia Balanova
- Yuliya V Solovieva
- Yuna He
- Yunjiang Yu
- Yury P Nikitin
- Yves Kameli
- Yves Martin-Prevel
- Yvonne T van der Schouw
- Zahra Mohammadi
- Zbigniew Gaciong
- Zbigniew Kulaga
- Zengchang Pang
- Zhamilya Battakova
- Zhamyila Usupova
- Zhanna Kalmatayeva
- Zhen-Yu Zhang
- Zhengming Chen
- Ziad A Abdeen
- Zivka Dika
- Zlatko Fras
- Zulfiqar A Bhutta
- Zulfiya Abdurrahmonova
- Zumin Shi
- Łukasz Kryst
- Publication venue
- Publication date
- 01/03/2024
- Field of study
Background Underweight and obesity are associated with adverse health outcomes throughout the life course. We
estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from
1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories.
Methods We used data from 3663 population-based studies with 222 million participants that measured height and
weight in representative samples of the general population. We used a Bayesian hierarchical model to estimate
trends in the prevalence of different BMI categories, separately for adults (age ≥20 years) and school-aged children
and adolescents (age 5–19 years), from 1990 to 2022 for 200 countries and territories. For adults, we report the
individual and combined prevalence of underweight (BMI <18·5 kg/m2) and obesity (BMI ≥30 kg/m2). For schoolaged children and adolescents, we report thinness (BMI <2 SD below the median of the WHO growth reference)
and obesity (BMI >2 SD above the median).
Findings From 1990 to 2022, the combined prevalence of underweight and obesity in adults decreased in
11 countries (6%) for women and 17 (9%) for men with a posterior probability of at least 0·80 that the observed
changes were true decreases. The combined prevalence increased in 162 countries (81%) for women and
140 countries (70%) for men with a posterior probability of at least 0·80. In 2022, the combined prevalence of
underweight and obesity was highest in island nations in the Caribbean and Polynesia and Micronesia, and
countries in the Middle East and north Africa. Obesity prevalence was higher than underweight with posterior
probability of at least 0·80 in 177 countries (89%) for women and 145 (73%) for men in 2022, whereas the converse
was true in 16 countries (8%) for women, and 39 (20%) for men. From 1990 to 2022, the combined prevalence of
thinness and obesity decreased among girls in five countries (3%) and among boys in 15 countries (8%) with a
posterior probability of at least 0·80, and increased among girls in 140 countries (70%) and boys in 137 countries (69%)
with a posterior probability of at least 0·80. The countries with highest combined prevalence of thinness and
obesity in school-aged children and adolescents in 2022 were in Polynesia and Micronesia and the Caribbean for
both sexes, and Chile and Qatar for boys. Combined prevalence was also high in some countries in south Asia, such
as India and Pakistan, where thinness remained prevalent despite having declined. In 2022, obesity in school-aged
children and adolescents was more prevalent than thinness with a posterior probability of at least 0·80 among girls
in 133 countries (67%) and boys in 125 countries (63%), whereas the converse was true in 35 countries (18%) and
42 countries (21%), respectively. In almost all countries for both adults and school-aged children and adolescents,
the increases in double burden were driven by increases in obesity, and decreases in double burden by declining
underweight or thinness.
Interpretation The combined burden of underweight and obesity has increased in most countries, driven by an
increase in obesity, while underweight and thinness remain prevalent in south Asia and parts of Africa. A healthy
nutrition transition that enhances access to nutritious foods is needed to address the remaining burden of
underweight while curbing and reversing the increase in obesit
Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants
- Author
- Abarca-Gomez Leandra
- Abdeen Ziad A
- Abdrakhmanova Shynar
- Abu-Rmeileh Niveen M
- Acosta-Cazares Benjamin
- Adams Robert J
- Aekplakorn Wichai
- Afsana Kaosar
- Afzal Shoaib
- Agdeppa Imelda A
- Aghazadeh-Attari Javad
- Aguilar-Salinas Carlos A
- Agyemang Charles
- Ahmad Mohamad Hasnan
- Ahmad Noor Ani
- Ahmadi Ali
- Ahmadi Naser
- Ahmed Soheir H
- Ahrens Wolfgang
- Aitmurzaeva Gulmira
- Ajlouni Kamel
- Al Nsour Mohannad
- Al-Hazzaa Hazzaa M
- Al-Othman Amani Rashed
- Al-Raddadi Rajaa
- Alarouj Monira
- AlBuhairan Fadia
- AlDhukair Shahla
- Ali Mohamed M
- Alkandari Abdullah
- Alkerwi Ala'a
- Allin Kristine
- Alvarez-Pedrerol Mar
- Aly Eman
- Amarapurkar Deepak N
- Amiri Parisa
- Amougou Norbert
- Amouyel Philippe
- Andersen Lars Bo
- Anderssen Sigmund A
- Angquist Lars
- Anjana Ranjit Mohan
- Ansari-Moghaddam Alireza
- Aounallah-Skhiri Hajer
- Araujo Joana
- Ariansen Inger
- Aris Tahir
- Arku Raphael E
- Arlappa Nimmathota
- Aryal Krishna K
- Aspelund Thor
- Assah Felix K
- Assuncao Maria Cecilia F
- Aung May Soe
- Auvinen Juha
- Avdicova Maria
- Azevedo Ana
- Azimi-Nezhad Mohsen
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- Azmin Mehrdad
- Babu Bontha V
- Baharudin Azli
- Bahijri Suhad
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- Banegas Jose R
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- Batista Rosangela L
- Battakova Zhamilya
- Batyrbek Assembekov
- Baur Louise A
- Beaglehole Robert
- Bebakar Wan Mohamad Wan
- Bel-Serrat Silvia
- Belavendra Antonisamy
- Ben Romdhane Habiba
- Benedics Judith
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- Bennett James E
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- Bentham James
- Bergh Ingunn Holden
- Berkinbayev Salim
- Bernabe-Ortiz Antonio
- Bernotiene Gailute
- Bettiol Heloisa
- Bezerra Jorge
- Bhagyalaxmi Aroor
- Bharadwaj Sumit
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- Bhutta Zulfiqar A
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- Bista Bihungum
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- Boker Lital Keinan
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- Bonilla-Vargas Alice
- Bopp Matthias
- Borghs Herman
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- Braeckevelt Lien
- Braeckman Lutgart
- Bragt Marjolijn CE
- Brajkovich Imperia
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- Bruno Graziella
- Bueno-de-Mesquita H Bas
- Bugge Anna
- Buoncristiano Marta
- Burazeri Genc
- Burns Con
- Cacciottolo Joseph
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- Cai Hui
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- Cameron Christine
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- Casajus Jose A
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- Celikcan Ertugrul
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- Cesar Juraci A
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- Chen Chien-Jen
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- Chen Shuohua
- Chen Zhengming
- Cheng Ching-Yu
- Cheraghian Bahman
- Chetrit Angela
- Chikova-Iscener Ekaterina
- Chinh Nguyen Huu
- Chiolero Arnaud
- Chiou Shu-Ti
- Chirita-Emandi Adela
- Chirita-Emandi Adela
- Chirlaque Maria-Dolores
- Cho Belong
- Christensen Kaare
- Christofaro Diego G
- Chudek Jerzy
- Cifkova Renata
- Cilia Michelle
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- Cisneros Julio Zuniga
- Claessens Frank
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- Crampin Amelia C
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- D'Arrigo Graziella
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- Dacica Liliana
- Dallongeville Jean
- Damasceno Albertino
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- Danaei Goodarz
- Danaei Goodarz
- Dankner Rachel
- Dantoft Thomas M
- Dasgupta Parasmani
- Dastgiri Saeed
- Dauchet Luc
- Davletov Kairat
- De Backer Guy
- De Bacquer Dirk
- de Gaetano Giovanni
- De Henauw Stefaan
- de Leon Antonio Cabrera
- de Oliveira Paula Duarte
- de Paiva Karina Mary
- De Ridder David
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- De Smedt Delphine
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- Deren Katarzyna
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- Dhimal Meghnath
- Di Castelnuovo Augusto F
- Di Cesare Mariachiara
- Dias-da-Costa Juvenal Soares
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- Dika Zivka
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- Duleva Vesselka
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- Eghtesad Sareh
- Eiben Gabriele
- Ekelund Ulf
- El Ati Jalila
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- Eldemire-Shearer Denise
- Eliasen Marie
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- Engle-Stone Reina
- Enguerran Macia
- Erasmus Rajiv T
- Erbel Raimund
- Erem Cihangir
- Eriksen Louise
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- Escobedo-de la Pena Jorge
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- Fall Caroline H
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- Ferrari Marika
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- Ferrieres Jean
- Figueiro Thamara Hubler
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- Foo Leng Huat
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- Franco Maria do Carmo
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- Fujita Yuki
- Fumihiko Matsuda
- Furusawa Takuro
- Gaciong Zbigniew
- Gafencu Mihai
- Galbarczyk Andrzej
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- Galvano Fabio
- Gao Jingli
- Garba Jamila Abubakar
- Garcia-de-la-Hera Manoli
- Garcia-Solano Marta
- Gareta Dickman
- Garnett Sarah P
- Gaspoz Jean-Michel
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- Geleijnse Johanna M
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- Godos Justyna
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- Grammatikopoulou Maria G
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- Grodzicki Tomasz
- Groholt Else Karin
- Grontved Anders
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- Gruden Gabriella
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- Gualdi-Russo Emanuela
- Guallar-Castillon Pilar
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- Gutzwiller Felix
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- Hadaegh Farzad
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- Haghshenas Rosa
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- Howitt Christina
- Htet Aung Soe
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- Hu Yonghua
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- Huhtaniemi Ilpo Tapani
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- Iotova Violeta
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- Ishida Takafumi
- Islam Muhammad
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- Jamrozik Konrad
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- Jennings Garry
- Jerome Charles Sossa
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- Kersting Mathilde
- Key Timothy
- Khader Yousef Saleh
- Khalili Davood
- Khang Young-Ho
- Khang Young-Ho
- Khanh Le Nguyen Bao
- Khaw Kay-Tee
- Kheiri Bahareh
- Kheradmand Motahareh
- Khosravi Alireza
- Khouw Ilse MSL
- Khuong Quynh Long
- Kiechl Stefan
- Kiechl-Kohlendorfer Ursula
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- Kim Hyeon Chang
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- Klakk Heidi
- Klimek Magdalena
- Klimont Jeannette
- Klumbiene Jurate
- Knoflach Michael
- Koirala Bhawesh
- Kolle Elin
- Kolsteren Patrick
- Konig Jurgen
- Korpelainen Raija
- Korrovits Paul
- Korzycka Magdalena
- Kos Jelena
- Koskinen Seppo
- Kouda Katsuyasu
- Kovacs Viktoria A
- Kowlessur Sudhir
- Koziel Slawomir
- Kratzer Wolfgang
- Kriemler Susi
- Kristensen Peter Lund
- Krokstad Steiner
- Kromhout Daan
- Krtalic Branimir
- Kruger Herculina S
- Kubinova Ruzena
- Kuciene Renata
- Kujala Urho M
- Kujundzic Enisa
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- Kumar R Krishna
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- Kunesova Marie
- Kurjata Pawel
- Kusuma Yadlapalli S
- Kuulasmaa Kari
- Kyobutungi Catherine
- Laamiri Fatima Zahra
- Laatikainen Tiina
- Lachat Carl
- Laid Youcef
- Lam Tai Hing
- Lambrinou Christina-Paulina
- Landais Edwige
- Lanska Vera
- Lappas Georg
- Larijani Bagher
- Latt Tint Swe
- Lauria Laura
- Laxmaiah Avula
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- Lazo-Porras Maria
- Le Port Agnes
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- Lee Jeannette
- Lee Jeonghee
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- Lehtimaki Terho
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- Li Yanping
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- Lilly Christa L
- Lim Wei-Yen
- Lima-Costa M Fernanda
- Lin Hsien-Ho
- Lin Xu
- Lin Yi-Ting
- Lind Lars
- Linneberg Allan
- Lissner Lauren
- Litwin Mieczyslaw
- Liu Jing
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- Lo Wei-Cheng
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- Lopes Luis
- Lopes Oscar
- Lopez Tania
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- Lotufo Paulo A
- Lozano Jose Eugenio
- Lukrafka Janice L
- Luksiene Dalia
- Lundqvist Annamari
- Lundqvist Robert
- Lunet Nuno
- Lunogelo Charles
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- Malekzadeh Reza
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- Malhotra Rahul
- Malyutina Sofia K
- Maniego Lynell V
- Manios Yannis
- Mann Jim I
- Mansour-Ghanaei Fariborz
- Manzato Enzo
- Margozzini Paula
- Marina Loreto Santa
- Markaki Anastasia
- Markey Oonagh
- Marques Larissa Pruner
- Marques-Vidal Pedro
- Marrugat Jaume
- Martin Rosemarie
- Martin-Prevel Yves
- Martinez Eduardo Salazar
- Martorell Reynaldo
- Martos Eva
- Marventano Stefano
- Mascarenhas Luis P
- Masoodi Shariq R
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- Mathur Prashant
- Matijasevich Alicia
- Matsha Tandi E
- Mavrogianni Christina
- Mazur Artur
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- McFarlane Shelly R
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- McLachlan Stela
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- McLean Scott B
- McNulty Breige A
- Mediene-Benchekor Sounnia
- Medzioniene Jurate
- Mehdipour Parinaz
- Mehlig Kirsten
- Mehrparvar Amir Houshang
- Meirhaeghe Aline
- Meisfjord Jorgen
- Meisinger Christa
- Menezes Ana Maria B
- Menon Geetha R
- Mensink Gert BM
- Menzano Maria Teresa
- Mereke Alibek
- Meshram Indrapal I
- Metspalu Andres
- Mi Jie
- Michaelsen Kim F
- Michels Nathalie
- Mikkel Kairit
- Milanovic Sanja Music
- Milkowska Karolina
- Miller Jody C
- Minderico Claudia S
- Mini GK
- Miquel Juan Francisco
- Miranda J Jaime
- Miranda J Jaime
- Mirjalili Mohammad Reza
- Mirkopoulou Daphne
- Mirrakhimov Erkin
- Misigoj-Durakovic Marjeta
- Mistretta Antonio
- Mocanu Veronica
- Modesti Pietro A
- Moghaddam Sahar Saeedi
- Mohajer Bahram
- Mohamed Mostafa K
- Mohamed Shukri F
- Mohammad Kazem
- Mohammadi Zahra
- Mohammadifard Noushin
- Mohammadpourhodki Reza
- Mohamud Wan Nazaimoon Wan
- Mohan Viswanathan
- Mohanna Salim
- Mohebbi Iraj
- Mohebi Farnam
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- Molbo Drude
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- Molnar Denes
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- Monterrubio-Flores Eric
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- Mortensen Erik Lykke
- Moschonis George
- Mossakowska Malgorzata
- Mostafa Aya
- Mota Jorge
- Mota-Pinto Anabela
- Motlagh Mohammad Esmaeel
- Motta Jorge
- Moura-dos-Santos Marcos Andre
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- Msyamboza Kelias P
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- Mugosa Boban
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- Mukhtorova Parvina
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- Musa Kamarul Imran
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- Mustafa Norlaila
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- Naderimagham Shohreh
- Nagel Gabriele
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- Namesna Jana
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- Nauck Matthias
- Neal William A
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- Nguyen Chung T
- Nguyen Nguyen D
- Nieto-Martinez Ramfis E
- Nikitin Yury P
- Ning Guang
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- Nishtar Sania
- Noale Marianna
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- Nogueira Helena
- Norat Teresa
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- Noto Davide
- Nowak-Szczepanska Natalia
- Nuhoglu Irfan
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- O'Reilly Dermot
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- Ochoa-Aviles Angelica M
- Oda Eiji
- Oh Kyungwon
- Ohara Kumiko
- Ohlsson Claes
- Ohtsuka Ryutaro
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- Paciorek Christopher J
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- Pagkalos Ioannis
- Pahomova Elena
- Pajak Andrzej
- Palli Domenico
- Palloni Alberto
- Palmieri Luigi
- Pan Wen-Harn
- Panda-Jonas Songhomitra
- Pandey Arvind
- Panza Francesco
- Papandreou Dimitrios
- Park Soon-Woo
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- Parnell Winsome R
- Parsaeian Mahboubeh
- Pascanu Ionela M
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- Peltonen Markku
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- Perez-Farinos Napoleon
- Peterkova Valentina
- Peters Annette
- Petersmann Astrid
- Petkeviciene Janina
- Petrauskiene Ausra
- Petrescu Constanta Huidumac
- Pettenuzzo Emanuela
- Peykari Niloofar
- Pichardo Rafael N
- Pierannunzio Daniela
- Pigeot Iris
- Pikhart Hynek
- Pilav Aida
- Pilotto Lorenza
- Pistelli Francesco
- Pitakaka Freda
- Piwonska Aleksandra
- Pizarro Andreia N
- Plans-Rubio Pedro
- Poh Bee Koon
- Pohlabeln Hermann
- Pop Raluca M
- Popovic Stevo R
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- Porta Miquel
- Posch Georg
- Poudyal Anil
- Poulimeneas Dimitrios
- Pouraram Hamed
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- Providencia Rui
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- Puiu Maria
- Punab Margus
- Qasrawi Radwan F
- Qorbani Mostafa
- Quang Ngoc La
- Quang Ngoc Nguyen
- Radic Ivana
- Radisauskas Ricardas
- Rahim Hanan F Abdul
- Rahim Norsyamlina Che Abdul
- Rahimikazerooni Salar
- Rahman Mahfuzar
- Rahman Mahmudur
- Raitakari Olli
- Raj Manu
- Rakhimova Ellina
- Rakhmatulloev Sherali
- Rakovac Ivo
- Ramachandran Ambady
- Ramke Jacqueline
- Ramos Elisabete
- Ramos Rafel
- Rampal Lekhraj
- Rampal Sanjay
- Rao Kodavanti Mallikharjuna
- Rao Sudha Ramachandra
- Rarra Vayia
- Rascon-Pacheco Ramon A
- Rasmussen Mette
- Rech Cassiano Ricardo
- Redon Josep
- Reganit Paul Ferdinand M
- Regecova Valeria
- Revilla Luis
- Rezaianzadeh Abbas
- Ribas-Barba Lourdes
- Ribeiro Robespierre
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- Richter Adrian
- Rigo Fernando
- Riley Leanne M
- Rinaldo Natascia
- Rito Ana
- Ritti-Dias Raphael M
- Rivera Juan A
- Robitaille Cynthia
- Roccaldo Romana
- Rodrigues Daniela
- Rodriguez-Artalejo Fernando
- Rodriguez-Martinez Andrea
- Rodriguez-Perez Maria del Cristo
- Rodriguez-Villamizar Laura A
- Roggenbuck Ulla
- Rojas-Martinez Rosalba
- Rojroongwasinkul Nipa
- Romaguera Dora
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- Rosario Angelika Schaffrath
- Rosario Rafaela V
- Rosengren Annika
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- Ruiz-Betancourt Blanca Sandra
- Rusakova Iuliia A
- Russo Paola
- Rust Petra
- Rutkowski Marcin
- Saavedra Maria Angeles Dal Re
- Sabanayagam Charumathi
- Sacchini Elena
- Sachdev Harshpal S
- Sadjadi Alireza
- Safarpour Ali Reza
- Safi Sare
- Safiri Saeid
- Saidi Olfa
- Saki Nader
- Salanave Benoit
- Salmeron Diego
- Salomaa Veikko
- Salonen Jukka T
- Salvetti Massimo
- Samoutian Margarita
- Sanchez-Abanto Jose
- Sandjaja
- Sans Susana
- Sant'Angelo Victoria Farrugia
- Santos Diana A
- Santos Ina S
- Santos Lelita C
- Santos Maria Paula
- Santos Osvaldo
- Santos Rute
- Sanz Sara Santos
- Saramies Jouko L
- Sardinha Luis B
- Sarrafzadegan Nizal
- Sathish Thirunavukkarasu
- Saum Kai-Uwe
- Savin Stefan
- Savva Savvas
- Savy Mathilde
- Sawada Norie
- Sbaraini Mariana
- Scazufca Marcia
- Schaan Beatriz D
- Schargrodsky Herman
- Schienkiewitz Anja
- Schindler Karin
- Schipf Sabine
- Schmidt Carsten O
- Schmidt Ida Maria
- Schnohr Peter
- Schottker Ben
- Schramm Sara
- Schramm Stine
- Schroder Helmut
- Schultsz Constance
- Schutte Aletta E
- Sebert Sylvain
- Sein Aye Aye
- Selamat Rusidah
- Sember Vedrana
- Sen Abhijit
- Senbanjo Idowu O
- Sepanlou Sadaf G
- Sequera Victor
- Serra-Majem Luis
- Servais Jennifer
- Sevcikova Ludmila
- Shalnova Svetlana A
- Shamah-Levy Teresa
- Shamshirgaran Morteza
- Shanthirani Coimbatore Subramaniam
- Sharafkhah Maryam
- Sharma Sanjib K
- Shaw Jonathan E
- Shayanrad Amaneh
- Shayesteh Ali Akbar
- Shengelia Lela
- Shi Zumin
- Shibuya Kenji
- Shimizu-Furusawa Hana
- Shin Dong Wook
- Shin Youchan
- Shirani Majid
- Shiri Rahman
- Shrestha Namuna
- Si-Ramlee Khairil
- Siani Alfonso
- Siantar Rosalynn
- Sibai Abla M
- Silva Antonio M
- Silva Diego Augusto Santos
- Simina Iulia Jurca
- Simon Mary
- Simons Judith
- Simons Leon A
- Sjoberg Agneta
- Sjostrom Michael
- Skodje Gry
- Slowikowska-Hilczer Jolanta
- Slusarczyk Przemyslaw
- Smeeth Liam
- So Hung-Kwan
- Soares Fernanda Cunha
- Sobek Grzegorz
- Sobngwi Eugene
- Sodemann Morten
- Soderberg Stefan
- Soekatri Moesijanti YE
- Soemantri Agustinus
- Sofat Reecha
- Solfrizzi Vincenzo
- Somi Mohammad Hossein
- Son Thai Pham
- Sonestedt Emily
- Song Yi
- Sophiea Marisa K
- Sorensen Thorkild IA
- Sorensen Thorkild IA
- Sorgjerd Elin P
- Soric Maroje
- Soric Maroje
- Soto-Rojas Victoria E
- Soumare Aicha
- Sovic Slavica
- Sparboe-Nilsen Bente
- Sparrenberger Karen
- Spinelli Angela
- Spiroski Igor
- Staessen Jan A
- Stamm Hanspeter
- Starc Gregor
- Starc Gregor
- Stathopoulou Maria G
- Staub Kaspar
- Stavreski Bill
- Steene-Johannessen Jostein
- Stehle Peter
- Stein Aryeh D
- Stergiou George S
- Stessman Jochanan
- Stevanovic Ranko
- Stevens Gretchen A
- Stieber Jutta
- Stockl Doris
- Stocks Tanja
- Stokwiszewski Jakub
- Stoyanova Ekaterina
- Stratton Gareth
- Stronks Karien
- Strufaldi Maria Wany
- Sturua Lela
- Suarez-Medina Ramon
- Suka Machi
- Sun Chien-An
- Sundstrom Johan
- Sung Yn-Tz
- Sunyer Jordi
- Suriyawongpaisal Paibul
- Swinburn Boyd A
- Sy Rody G
- Syddall Holly E
- Sylva Rene Charles
- Szklo Moyses
- Szponar Lucjan
- Taddei Cristina
- Tai E Shyong
- Tammesoo Mari-Liis
- Tamosiunas Abdonas
- Tan Eng Joo
- Tang Xun
- Tanser Frank
- Tao Yong
- Tarawneh Mohammed Rasoul
- Tarp Jakob
- Tarqui-Mamani Carolina B
- Taylor Anne
- Taylor Julie
- Tchibindat Felicite
- Tebar William R
- Tell Grethe S
- Tello Tania
- Thankappan KR
- Thein Thein Htay
- Theobald Holger
- Theodoridis Xenophon
- Thet Thet Mu
- Thi Tuyet-Hanh Tran
- Thijs Lutgarde
- Thomas Nihal
- Thuesen Betina H
- Ticha Lubica
- Timmermans Erik J
- Tjonneland Anne
- Tolonen Hanna K
- Tolstrup Janne S
- Topbas Murat
- Topor-Madry Roman
- Torheim Liv Elin
- Tormo Maria Jose
- Tornaritis Michael J
- Torrent Maties
- Torres-Collado Laura
- Toselli Stefania
- Traissac Pierre
- Tran Quoc Bao
- Trichopoulos Dimitrios
- Trichopoulou Antonia
- Trinh Oanh TH
- Trivedi Atul
- Tshepo Lechaba
- Tsigga Maria
- Tsugane Shoichiro
- Tuliakova Azaliia M
- Tulloch-Reid Marshall K
- Tullu Fikru
- Tuomainen Tomi-Pekka
- Tuomilehto Jaakko
- Turley Maria L
- Tynelius Per
- Tzotzas Themistoklis
- Tzourio Christophe
- Ueda Peter
- Ugel Eunice
- Ukoli Flora AM
- Ulmer Hanno
- Unal Belgin
- Usupova Zhamyila
- Uusitalo Hannu MT
- Uysal Nalan
- Vaitkeviciute Justina
- Valdivia Gonzalo
- Vale Susana
- Valvi Damaskini
- van Dam Rob M
- Van der Heyden Johan
- van der Schouw Yvonne T
- Van Herck Koen
- van Valkengoed Irene GM
- Vanderschueren Dirk
- Vanuzzo Diego
- Varbo Anette
- Varela-Moreiras Gregorio
- Varona-Perez Patricia
- Vasan Senthil K
- Vega Tomas
- Veidebaum Toomas
- Velasquez-Melendez Gustavo
- Velika Biruta
- Veronesi Giovanni
- Verschuren WM Monique
- Victora Cesar G
- Viegi Giovanni
- Viet Lucie
- Villalpando Salvador
- Vineis Paolo
- Vioque Jesus
- Virtanen Jyrki K
- Visser Marjolein
- Visvikis-Siest Sophie
- Viswanathan Bharathi
- Vladulescu Mihaela
- Vlasoff Tiina
- Vocanec Dorja
- Volzke Henry
- Voutilainen Ari
- Voutilainen Sari
- Vrijheid Martine
- Vrijkotte Tanja GM
- Vrkic Tajana Zeljkovic
- Wade Alisha N
- Wagner Aline
- Waldhor Thomas
- Walton Janette
- Wambiya Elvis OA
- Wang Ming-Dong
- Wang Ningli
- Wang Qian
- Wang Xiangjun
- Wang Ya Xing
- Wang Ying-Wei
- Wannamethee S Goya
- Wareham Nicholas
- Weber Adelheid
- Wedderkopp Niels
- Weerasekera Deepa
- Weghuber Daniel
- Wei Wenbin
- Weres Aneta
- Werner Bo
- Whincup Peter H
- Widhalm Kurt
- Widyahening Indah S
- Wiecek Andrzej
- Wilks Rainford J
- Willeit Johann
- Willeit Peter
- Williams Julianne
- Wilsgaard Tom
- Wojtyniak Bogdan
- Wong Andrew
- Wong Jyh Eiin
- Wong Norazizah Ibrahim
- Wong Tien Yin
- Wong-McClure Roy A
- Woo Jean
- Woodward Mark
- Wu Frederick C
- Wu Jianfeng
- Wu Li Juan
- Wu Shouling
- Xu Haiquan
- Xu Liang
- Yaacob Nor Azwany
- Yamborisut Uruwan
- Yan Weili
- Yang Ling
- Yang Xiaoguang
- Yang Yang
- Yardim Nazan
- Yaseri Mehdi
- Yasuharu Tabara
- Ye Xingwang
- Yiallouros Panayiotis K
- Yoosefi Moein
- Yoshihara Akihiro
- You Qi Sheng
- You San-Lin
- Younger-Coleman Novie O
- Yusof Safiah Md
- Yusoff Ahmad Faudzi
- Yusoff Muhammad Fadhli Mohd
- Zaccagni Luciana
- Zafiropulos Vassilis
- Zainuddin Ahmad A
- Zainuddin Ahmad A
- Zakavi Seyed Rasoul
- Zamani Farhad
- Zambon Sabina
- Zampelas Antonis
- Zamrazilova Hana
- Zapata Maria Elisa
- Zargar Abdul Hamid
- Zaw Ko Ko
- Zdrojewski Tomasz
- Zeng Yi
- Zhang Luxia
- Zhang Zhen-Yu
- Zhao Dong
- Zhao Ming-Hui
- Zhao Wenhua
- Zhen Shiqi
- Zheng Wei
- Zheng Yingfeng
- Zholdin Bekbolat
- Zhou Bin
- Zhou Maigeng
- Zhu Dan
- Zocalo Yanina
- Zuziak Monika
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2020
- Field of study
Summary Background Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents. Methods For this pooled analysis, we used a database of cardiometabolic risk factors collated by the Non-Communicable Disease Risk Factor Collaboration. We applied a Bayesian hierarchical model to estimate trends from 1985 to 2019 in mean height and mean BMI in 1-year age groups for ages 5–19 years. The model allowed for non-linear changes over time in mean height and mean BMI and for non-linear changes with age of children and adolescents, including periods of rapid growth during adolescence. Findings We pooled data from 2181 population-based studies, with measurements of height and weight in 65 million participants in 200 countries and territories. In 2019, we estimated a difference of 20 cm or higher in mean height of 19-year-old adolescents between countries with the tallest populations (the Netherlands, Montenegro, Estonia, and Bosnia and Herzegovina for boys; and the Netherlands, Montenegro, Denmark, and Iceland for girls) and those with the shortest populations (Timor-Leste, Laos, Solomon Islands, and Papua New Guinea for boys; and Guatemala, Bangladesh, Nepal, and Timor-Leste for girls). In the same year, the difference between the highest mean BMI (in Pacific island countries, Kuwait, Bahrain, The Bahamas, Chile, the USA, and New Zealand for both boys and girls and in South Africa for girls) and lowest mean BMI (in India, Bangladesh, Timor-Leste, Ethiopia, and Chad for boys and girls; and in Japan and Romania for girls) was approximately 9–10 kg/m2. In some countries, children aged 5 years started with healthier height or BMI than the global median and, in some cases, as healthy as the best performing countries, but they became progressively less healthy compared with their comparators as they grew older by not growing as tall (eg, boys in Austria and Barbados, and girls in Belgium and Puerto Rico) or gaining too much weight for their height (eg, girls and boys in Kuwait, Bahrain, Fiji, Jamaica, and Mexico; and girls in South Africa and New Zealand). In other countries, growing children overtook the height of their comparators (eg, Latvia, Czech Republic, Morocco, and Iran) or curbed their weight gain (eg, Italy, France, and Croatia) in late childhood and adolescence. When changes in both height and BMI were considered, girls in South Korea, Vietnam, Saudi Arabia, Turkey, and some central Asian countries (eg, Armenia and Azerbaijan), and boys in central and western Europe (eg, Portugal, Denmark, Poland, and Montenegro) had the healthiest changes in anthropometric status over the past 3·5 decades because, compared with children and adolescents in other countries, they had a much larger gain in height than they did in BMI. The unhealthiest changes—gaining too little height, too much weight for their height compared with children in other countries, or both—occurred in many countries in sub-Saharan Africa, New Zealand, and the USA for boys and girls; in Malaysia and some Pacific island nations for boys; and in Mexico for girls. Interpretation The height and BMI trajectories over age and time of school-aged children and adolescents are highly variable across countries, which indicates heterogeneous nutritional quality and lifelong health advantages and risks
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