Comparative Study of Physico- chemical Parameters of Ground water of Residential and Industrial area of Sirgitti in Bilaspur District

Water is available in abundance on the earth. It is one of the main reasons which make life possible on our planet. The quality strength and type of sewage depends upon the human population, industrialization, deforestation and life style of people. Analytical explorations of some selected physico- chemical parameter have been made on the ground water bodies of Sirgitti industrial area. In the present comparative study for physico-chemical analysis water samples were collected  from to different locations the residential and industrial area of  Sirgitti in Bilaspur district. The laboratory test of the collected water samples were performed for analysis of some selected physico-chemical parameters such as pH, EC, TDS, DO, COD, Total hardness, Fluoride, chloride etc. The methods employed for the analysis as per standard  methods recommended by APHA and WHO standard of drinking water. The obtained values are compared with the standard limit. The results of this study reveals that in the industrial area of the physico-chemical parameters higher in the maximum permissible limit of WHO with variations in some parameters. Both the sampling stations groundwater unsuitable for domestic, irrigation and drinking purposes but the industrial area of BEC fertilizers groundwater is more polluted than the Adarsh nagar residential area of Sirgitti. So it is essential that the quality of ground water should be regular checked and also needs treatment before direct use

Scholars Journal of Arts, Humanities and Social Sciences ISSN 2347-5374 (Online) Role of Women in India's Independence

Abstract: In this paper, the contribution of women so far the independence of the country has been presented. It has been found in literature that a huge number of Marathi women openly took part in the Swadeshi Movement in 1906. The Women play an important role when Mahatma Gandhi ji launched countrywide movement against the Rowlett Act (1918). The contribution o

Thigh-length compression stockings and DVT after stroke

Controversy exists as to whether neoadjuvant chemotherapy improves survival in patients with invasive bladder cancer, despite randomised controlled trials of more than 3000 patients. We undertook a systematic review and meta-analysis to assess the effect of such treatment on survival in patients with this disease

Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Background Azithromycin has been proposed as a treatment for COVID-19 on the basis of its immunomodulatory actions. We aimed to evaluate the safety and efficacy of azithromycin in patients admitted to hospital with COVID-19. Methods In this randomised, controlled, open-label, adaptive platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]), several possible treatments were compared with usual care in patients admitted to hospital with COVID-19 in the UK. The trial is underway at 176 hospitals in the UK. Eligible and consenting patients were randomly allocated to either usual standard of care alone or usual standard of care plus azithromycin 500 mg once per day by mouth or intravenously for 10 days or until discharge (or allocation to one of the other RECOVERY treatment groups). Patients were assigned via web-based simple (unstratified) randomisation with allocation concealment and were twice as likely to be randomly assigned to usual care than to any of the active treatment groups. Participants and local study staff were not masked to the allocated treatment, but all others involved in the trial were masked to the outcome data during the trial. The primary outcome was 28-day all-cause mortality, assessed in the intention-to-treat population. The trial is registered with ISRCTN, 50189673, and ClinicalTrials.gov, NCT04381936. Findings Between April 7 and Nov 27, 2020, of 16 442 patients enrolled in the RECOVERY trial, 9433 (57%) were eligible and 7763 were included in the assessment of azithromycin. The mean age of these study participants was 65·3 years (SD 15·7) and approximately a third were women (2944 [38%] of 7763). 2582 patients were randomly allocated to receive azithromycin and 5181 patients were randomly allocated to usual care alone. Overall, 561 (22%) patients allocated to azithromycin and 1162 (22%) patients allocated to usual care died within 28 days (rate ratio 0·97, 95% CI 0·87–1·07; p=0·50). No significant difference was seen in duration of hospital stay (median 10 days [IQR 5 to >28] vs 11 days [5 to >28]) or the proportion of patients discharged from hospital alive within 28 days (rate ratio 1·04, 95% CI 0·98–1·10; p=0·19). Among those not on invasive mechanical ventilation at baseline, no significant difference was seen in the proportion meeting the composite endpoint of invasive mechanical ventilation or death (risk ratio 0·95, 95% CI 0·87–1·03; p=0·24). Interpretation In patients admitted to hospital with COVID-19, azithromycin did not improve survival or other prespecified clinical outcomes. Azithromycin use in patients admitted to hospital with COVID-19 should be restricted to patients in whom there is a clear antimicrobial indication. Funding UK Research and Innovation (Medical Research Council) and National Institute of Health Research