The Ambidextrous Employee: Exploiting and Exploring People's Potential

In this introduction to the special issue we propose the main problems and issues that are addressed, namely, how the ambidextrous ideal in contemporary working life plays out at the individual level. Today, employees need to have the intellectual, social, and physical capacity, will, strength and ability to produce, execute, refine, and choose. But they also need to have the intellectual, social and physical capacity, will, strength and ability to experiment, search, and play. They need both be able to discipline themselves and “go crazy.” They need both focus and fantasy. They need to adhere to organizational norms and values, as well as challenge them. We discuss the challenges and problems that face the ambidextrous person, and why he or she cannot remain but an ideal character. At the end of this introduction, we outline the contributions of all authors who seek to explore in various ways how the ambidextrous employee comes into play in contemporary society and its human and organizational consequences

Measurement of the Bottom-Strange Meson Mixing Phase in the Full CDF Data Set

We report a measurement of the bottom-strange meson mixing phase \beta_s using the time evolution of B0_s -> J/\psi (->\mu+\mu-) \phi (-> K+ K-) decays in which the quark-flavor content of the bottom-strange meson is identified at production. This measurement uses the full data set of proton-antiproton collisions at sqrt(s)= 1.96 TeV collected by the Collider Detector experiment at the Fermilab Tevatron, corresponding to 9.6 fb-1 of integrated luminosity. We report confidence regions in the two-dimensional space of \beta_s and the B0_s decay-width difference \Delta\Gamma_s, and measure \beta_s in [-\pi/2, -1.51] U [-0.06, 0.30] U [1.26, \pi/2] at the 68% confidence level, in agreement with the standard model expectation. Assuming the standard model value of \beta_s, we also determine \Delta\Gamma_s = 0.068 +- 0.026 (stat) +- 0.009 (syst) ps-1 and the mean B0_s lifetime, \tau_s = 1.528 +- 0.019 (stat) +- 0.009 (syst) ps, which are consistent and competitive with determinations by other experiments.Comment: 8 pages, 2 figures, Phys. Rev. Lett 109, 171802 (2012

Repositioning of the global epicentre of non-optimal cholesterol

High blood cholesterol is typically considered a feature of wealthy western countries1,2. However, dietary and behavioural determinants of blood cholesterol are changing rapidly throughout the world3 and countries are using lipid-lowering medications at varying rates. These changes can have distinct effects on the levels of high-density lipoprotein (HDL) cholesterol and non-HDL cholesterol, which have different effects on human health4,5. However, the trends of HDL and non-HDL cholesterol levels over time have not been previously reported in a global analysis. Here we pooled 1,127 population-based studies that measured blood lipids in 102.6 million individuals aged 18 years and older to estimate trends from 1980 to 2018 in mean total, non-HDL and HDL cholesterol levels for 200 countries. Globally, there was little change in total or non-HDL cholesterol from 1980 to 2018. This was a net effect of increases in low- and middle-income countries, especially in east and southeast Asia, and decreases in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe. As a result, countries with the highest level of non-HDL cholesterol—which is a marker of cardiovascular risk—changed from those in western Europe such as Belgium, Finland, Greenland, Iceland, Norway, Sweden, Switzerland and Malta in 1980 to those in Asia and the Pacific, such as Tokelau, Malaysia, The Philippines and Thailand. In 2017, high non-HDL cholesterol was responsible for an estimated 3.9 million (95% credible interval 3.7 million–4.2 million) worldwide deaths, half of which occurred in east, southeast and south Asia. The global repositioning of lipid-related risk, with non-optimal cholesterol shifting from a distinct feature of high-income countries in northwestern Europe, north America and Australasia to one that affects countries in east and southeast Asia and Oceania should motivate the use of population-based policies and personal interventions to improve nutrition and enhance access to treatment throughout the world.</p

Repositioning of the global epicentre of non-optimal cholesterol

High blood cholesterol is typically considered a feature of wealthy western countries1,2. However, dietary and behavioural determinants of blood cholesterol are changing rapidly throughout the world3 and countries are using lipid-lowering medications at varying rates. These changes can have distinct effects on the levels of high-density lipoprotein (HDL) cholesterol and non-HDL cholesterol, which have different effects on human health4,5. However, the trends of HDL and non-HDL cholesterol levels over time have not been previously reported in a global analysis. Here we pooled 1,127 population-based studies that measured blood lipids in 102.6 million individuals aged 18 years and older to estimate trends from 1980 to 2018 in mean total, non-HDL and HDL cholesterol levels for 200 countries. Globally, there was little change in total or non-HDL cholesterol from 1980 to 2018. This was a net effect of increases in low- and middle-income countries, especially in east and southeast Asia, and decreases in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe. As a result, countries with the highest level of non-HDL cholesterol�which is a marker of cardiovascular risk�changed from those in western Europe such as Belgium, Finland, Greenland, Iceland, Norway, Sweden, Switzerland and Malta in 1980 to those in Asia and the Pacific, such as Tokelau, Malaysia, The Philippines and Thailand. In 2017, high non-HDL cholesterol was responsible for an estimated 3.9 million (95 credible interval 3.7 million�4.2 million) worldwide deaths, half of which occurred in east, southeast and south Asia. The global repositioning of lipid-related risk, with non-optimal cholesterol shifting from a distinct feature of high-income countries in northwestern Europe, north America and Australasia to one that affects countries in east and southeast Asia and Oceania should motivate the use of population-based policies and personal interventions to improve nutrition and enhance access to treatment throughout the world. © 2020, The Author(s), under exclusive licence to Springer Nature Limited

Rising rural body-mass index is the main driver of the global obesity epidemic in adults

Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities 1,2 . This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity 3�6 . Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean BMI segregated by place of residence (a rural or urban area) from 1985 to 2017. We show that, contrary to the dominant paradigm, more than 55 of the global rise in mean BMI from 1985 to 2017�and more than 80 in some low- and middle-income regions�was due to increases in BMI in rural areas. This large contribution stems from the fact that, with the exception of women in sub-Saharan Africa, BMI is increasing at the same rate or faster in rural areas than in cities in low- and middle-income regions. These trends have in turn resulted in a closing�and in some countries reversal�of the gap in BMI between urban and rural areas in low- and middle-income countries, especially for women. In high-income and industrialized countries, we noted a persistently higher rural BMI, especially for women. There is an urgent need for an integrated approach to rural nutrition that enhances financial and physical access to healthy foods, to avoid replacing the rural undernutrition disadvantage in poor countries with a more general malnutrition disadvantage that entails excessive consumption of low-quality calories. © 2019, The Author(s)

Does Pol I talk to Pol II? Coordination of RNA polymerases in ribosome biogenesis.

We establish a result on the large sieve with square moduli. These bounds improve recent results by S. Baier [S. Baier, On the large sieve with sparse sets of moduli, J. Ramanujan Math. Soc. 21 (2006) 279-295] and L. Zhao [L. Zhao, Large sieve inequality for characters to square moduli, Acta Arith. 112 (3) (2004) 297-308]. © 2007 Elsevier Inc. All rights reserved

Computer simulation of the dynamics of neutral and charged dendrimers

Dynamic properties of dilute solutions of neutral and charged dendrimers with explicit excluded-volume, electrostatic, and hydrodynamic interactions have been investigated by Brownian dynamics simulation. Three different types of motions in dendrimers up to g = 5 generations have been considered: the motion of a dendrimer as a whole; the size and shape fluctuations (pulsations); the local reorientations of the individual monomers. The influence of the excluded-volume, electrostatic, and hydrodynamic interactions on these motions has been studied. The characteristic relaxation times have been compared with the theoretical predictions of the Rouse and Zimm models. The self-diffusion of a dendrimer can be described with the help of the preaveraged Zimm approach, and a dendrimer may be considered as an impenetrable sphere with the hydrodynamic radius Rh. For both neutral and charged dendrimers the hydrodynamic radius is smaller than the gyration radius Rg. The dynamics of the size fluctuations for a dendrimer with rigid spacers differs significantly from the theoretical predictions for a dendrimer with flexible spacers. The relaxation of these fluctuations is weakly sensitive to the presence of the hydrodynamic interactions, and the behavior of a dendrimer is close to that of an elastic body in a viscous medium. The local orientational mobility of individual monomers is significantly influenced by the ionization of the terminal groups

Computer simulation of complexes of dendrimers with linear polyelectrolytes.

Brownian dynamics computer simulations have been carried out of complexes formed by charged dendrimers and oppositely charged linear polymer chains of different degree of polymerization Nch. Bead-rod freely jointed models in the Debye-Hückel approximation without hydrodynamic interactions have been considered. Mean-square radii of gyration together with the radial density distribution functions have been calculated separately for a complex, a dendrimer, and a linear chain in a complex. The mean-square radius of gyration, the different monomer radial distribution functions, and the static structure factor for a dendrimer in a complex with long enough chains are very close to those for a single neutral dendrimer. The monomers of the linear chains with Nch equal to the number of the dendrimer's terminal charged groups are located very close to these terminal groups. For longer chains the total number of the chain monomers adsorbed onto a dendrimer exceeds the number that is necessary for a dendrimer neutralization, and the overcharging phenomenon is observed. Comparison with predictions of the correlation theory has been carried out