40 research outputs found
The twilight of the Liberal Social Contract? On the Reception of Rawlsian Political Liberalism
- Author
- Achinstein
- Achinstein
- Achinstein
- Achterhuis
- Adams
- Adorno
- Adorno
- Adorno
- Adorno
- Agamben
- Ahmed
- al-Hibri
- Albert
- Alcoff
- Alexander
- Alighieri
- Allen
- Allhoff
- Allhoff
- Alpyagil
- Alston
- Ames
- Améry
- Anderson
- Ankersmit
- Ankersmit
- Ankersmit
- Ankersmit
- Ankersmit
- Annas
- Anscombe
- Anscombe
- Anscombe
- Antony
- Apel
- Apel
- Apel
- Apple
- Aquinas
- Aquinas
- Archambault
- Arendt
- Arendt
- Armstrong
- Armstrong
- Armstrong
- Armstrong
- Armstrong
- Arnold
- Arnold
- Aschheim
- Audi
- Audi
- Augustine
- Augustine
- Aune
- Aurobindo
- Austin
- Austin
- Auxier
- Ayer
- Ayer
- Ayer
- Ayer
- Bach
- Baert
- Baier
- Baker
- Baker
- Baker
- Bales
- Ball
- Ball
- Barad
- Barnes
- Barnes
- Baron
- Barrett
- Barwise
- Baudrillard
- Baumgartner
- Baxley
- Beaney
- Beaney
- Beardsley
- Beardsley
- Beardsley
- Beaty
- Beauvoir
- Beauvoir
- Beauvoir
- Beck
- Becker
- Becker
- Bekoff
- Bellah
- Benjamin
- Bennett
- Bennett
- Bennett
- Bennett
- Bergoffen
- Berleant
- Berlin
- Bernasconi
- Bernstein
- Bernstein
- Besley
- Besley
- Bilimoria
- Bird
- Bishop
- Blake
- Blattner
- Block
- Block
- Block
- Bloomfield
- Bloor
- Boas
- Boden
- Boden
- Boden
- Boler
- Bolzano
- Bondy
- Bookchin
- Bordo
- Bordwell
- Borgmann
- Botts
- Bourdieu
- Bovens
- Bowles
- Boyd
- Bradshaw
- Braithwaite
- Brand
- Brandis
- Brandom
- Brandom
- Brandt
- Bratman
- Braudy
- Bridges
- Bridges
- Brink
- Broome
- Brown
- Brown
- Brown
- Brown
- Brown
- Brucker
- Bruner
- Brunner
- Bruya
- Bryson
- Bubner
- Budd
- Budd
- Bunge
- Burbules
- Butler
- Butler
- Butler
- Cage
- Cahill
- Calle-Gruber
- Callicott
- Campbell
- Caputo
- Carlson
- Carnap
- Carnap
- Carnap
- Carnap
- Carnap
- Carnap
- Carnap
- Carnap
- Carnap
- Carnap
- Carnap
- Carnap
- Carr
- Carr
- Carroll
- Carroll
- Carroll
- Carroll
- Carroll
- Cartwright
- Carus
- Cavell
- Cavell
- Cavell
- Cavell
- Cavell
- Cerbone
- Chakrabarti
- Chakrabarti
- Chakrabarti
- Chakrabarti
- Chalmers
- Chalmers
- Chalmers
- Chalmers
- Chalmers
- Chalmers
- Chalmers
- Chastain
- Chatterjee
- Chenyang
- Chomsky
- Chomsky
- Chomsky
- Chomsky
- Chomsky
- Chomsky
- Chomsky
- Chomsky
- Chomsky
- Chomsky
- Chomsky
- Chomsky
- Chrisley
- Chrisley
- Church
- Churchland
- Churchland
- Churchland
- Churchland
- Churchland
- Clark
- Clark
- Clark
- Clark
- Clarke
- Cleveland
- Cobb
- Cohen
- Cohen
- Cohen
- Collingwood
- Collingwood
- Collingwood
- Collingwood
- Collins
- Collins
- Collins
- Conant
- Connolly
- Conze
- Cooper
- Cooper
- Cooper
- Copleston
- Correia
- Correia
- Correia
- Cowherds
- Cowherds
- Cowie
- Craik
- Crary
- Crisp
- Cronin
- Cronon
- Crowe
- Cua
- Currie
- Dahlstrom
- Dancy
- Dancy
- Danto
- Danto
- Danto
- Danto
- Danto
- Danto
- Darwall
- Darwin
- Dasgupta
- Dasgupta
- Dasti
- Davidson
- Davidson
- Davidson
- Davidson
- Davidson
- Davies
- Davies
- Davies
- Davies
- Davis
- Davis
- Dawkins
- de Bary
- de Bary
- De Caro
- De Caro
- de Waal
- de Waal
- Dearden
- Deleuze
- Deleuze
- Deleuze
- Denis
- Denis
- Dennett
- Dennett
- Dennett
- Dennett
- Dennett
- Dennett
- Dennett
- Dennett
- Dennett
- Depoortere
- DeRose
- deRosset
- Derrida
- Derrida
- Derrida
- Derrida
- Derrida
- Derrida
- Derrida
- Derrida
- Devall
- Devall
- DeVries
- Dewey
- Dewey
- Dewey
- Dewey
- Dewey
- Dewey
- Dewey
- Di Cesare
- Diamond
- Dickie
- Dickie
- Dilthey
- Diprose
- Dobzhansky
- Donagan
- Donovan
- Downs
- Draper
- Dravid
- Dray
- Dray
- Dray
- Dreben
- Dretske
- Dretske
- Dretske
- Dretske
- Dretske
- Dreyfus
- Dreyfus
- Dreyfus
- Dreyfus
- Dreyfus
- Dreyfus
- Dreyfus
- Dreyfus
- Dreyfus
- Driver
- Driver
- Ducasse
- Duhem
- Dummett
- Dummett
- Dummett
- Duncan
- Dupré
- Durbin
- Dutihl Novaes
- Dutton
- D’Agostino
- D’Amato
- Earman
- Earman
- Earman
- Ebbs
- Eddington
- Eliot
- Ellis
- Emerson
- Engstrom
- Eribon
- Evans
- Evernden
- Fackenheim
- Fackenheim
- Fairbairn
- Falk
- Farrell
- Faye
- Feagin
- Feenberg
- Feenberg
- Feenberg
- Feferman
- Feigl
- Fendler
- Fendler
- Ferrara
- Feyerabend
- Figal
- Fine
- Fine
- Fine
- Finlayson
- Firth
- Firth
- Flew
- Flew
- Floridi
- Fodor
- Fodor
- Fodor
- Fodor
- Fodor
- Foot
- Forst
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Fox
- Fox
- Frankena
- Frankfurt
- Franks
- Franks
- Franks
- Fraser
- Freddoso
- Freeland
- Freeland
- Freeland
- Freeman
- Frege
- Frege
- Freire
- Freire
- Freud
- Friedan
- Friedlander
- Friedman
- Friedman
- Friedman
- Friedman
- Friis
- Frost-Arnold
- Fung
- Fung
- Føllesdal
- Føllesdal
- Gadamer
- Gadamer
- Gadamer
- Gadamer
- Gadamer
- Gadamer
- Gadamer
- Gadamer
- Gadamer
- Gadamer
- Galison
- Gallie
- Gandy
- Ganeri
- Ganeri
- Garber
- Garber
- Gardiner
- Gardiner
- Gardiner
- Gardner
- Garfield
- Garrison
- Gascoigne
- Gatens
- Gaus
- Gaus
- Gaus
- Gaut
- Gaut
- George
- George
- George
- Gilligan
- Gillon
- Giunti
- Glendinning
- Glymour
- Glymour
- Godfrey-Smith
- Godlovitch
- Goehr
- Goldblatt
- Goldman
- Goldman
- Goldman
- Golomb
- Goodman
- Goodman
- Gordon
- Gordon
- Gore
- Goto-Jones
- Gould
- Gould
- Gracia
- Gracia
- Gracyk
- Gracyk
- Graham
- Graham
- Gray
- Greco
- Greco
- Green
- Gregor
- Gregory
- Grene
- Grene
- Grene
- Grice
- Grice
- Griffiths
- Griffiths
- Grondin
- Grondin
- Grondin
- Grondin
- Grosz
- Gruen
- Grünbaum
- Guarino
- Guay
- Guignon
- Guignon
- Gupta
- Guyer
- Guyer
- Guyer
- Gödel
- Gödel
- Habermas
- Habermas
- Habermas
- Habermas
- Habermas
- Habermas
- Habermas
- Habermas
- Habermas
- Habermas
- Habermas
- Habermas
- Hacker
- Hacking
- Hacking
- Hacking
- Hagberg
- Hallward
- Hamilton
- Hamilton
- Hamlyn
- Hampshire
- Hanke
- Hansen
- Hansen
- Hanson
- Haraway
- Hare
- Hare
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- Harman
- Harman
- Harman
- Harman
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- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
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- Hempel
- Herman
- Herman
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- Hershock
- Hershowitz
- Hesse
- Hesse
- Hesse
- Heyting
- Hick
- Hick
- Hick
- Hickman
- Higgins
- Hill
- Hill
- Hill
- Hintikka
- Hirsch
- Hirst
- Hirst
- Hockett
- Hoerl
- Hofweber
- Honig
- Honneth
- Honneth
- Honneth
- Honneth
- Hook
- Hooker
- hooks
- hooks
- Hookway
- Hopkins
- Horgan
- Horkheimer
- Horkheimer
- Horkheimer
- Horkheimer
- Hornsby
- Horwich
- Howard-Snyder
- Howard-Snyder
- Howson
- Hrdy
- Hu
- Hubbard
- Hull
- Hume
- Hunter
- Hursthouse
- Hursthouse
- Hursthouse
- Husserl
- Husserl
- Hylton
- Hylton
- Höffe
- Ihde
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- Iseminger
- Ivanhoe
- Izutsu
- Izutsu
- Jackson
- Jackson
- Jackson
- James
- Jammer
- Javier-Castellanos
- Jaynes
- Jeffrey
- Jesperson
- Jesperson
- Jesperson
- Jonas
- Jonas
- Jones
- Joos
- Jost
- Juhl
- Kagan
- Kajiyama
- Kamm
- Kamm
- Kamp
- Kane
- Kant
- Kant
- Kant
- Kaplan
- Kasulis
- Kasulis
- Katz
- Katz
- Katz
- Katz
- Katz
- Kaufmann
- Kaufmann
- Kazepides
- Keane
- Kearney
- Keiji
- Keiji
- Keller
- Kelly
- Kelly
- Kenny
- Kenny
- Khoo
- Kieran
- Kieran
- Kierkegaard
- Kierkegaard
- Kim
- Kim
- King
- Kirk
- Kirloskar-Steinbach
- Kitarō
- Kitarō
- Kitarō
- Kitarō
- Kitcher
- Kitcher
- Kivy
- Kivy
- Kivy
- Kivy
- Klosko
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- Minteer
- Misak
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- Moltmann
- Montague
- Moore
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- Moran
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- Motherwell
- Mou
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- Mouffe
- Mulhall
- Mulhall
- Mulhall
- Muller
- Mumford
- Mumford
- Mumford
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- Murphy
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- Nagel
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- Nehamas
- Neurath
- Newell
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- Nidditch
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- Noddings
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- Nozick
- Noë
- Nussbaum
- Nussbaum
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- Nussbaum
- Oakeshott
- Odin
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- Olssen
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- Oppenheim
- Oppy
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- Otero
- Otsuka
- Owen
- Oyama
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- O’Neil
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- Pettit
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- Phillips
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- Place
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- Quinn
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- Reiner
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- Ricoeur
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- Robinson
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- White
- White
- White
- Whitt
- Whyte
- Widerker
- Wierenga
- Wiesel
- Wild
- Willett
- Williams
- Williams
- Williams
- Williams
- Williams
- Williams
- Williams
- Williams
- Williams
- Williams
- Williams
- Williams
- Williams
- Williamson
- Wilson
- Wilson
- Wilson
- Wilson
- Wimsatt
- Wimsatt
- Wimsatt
- Winch
- Windelband
- Winner
- Wittgenstein
- Wittgenstein
- Wittgenstein
- Wittgenstein
- Wittgenstein
- Wittgenstein
- Wittgenstein
- Wittgenstein
- Wittgenstein
- Wittgenstein
- Wittgenstein
- Wittgenstein
- Wittgenstein
- Wolff
- Wolin
- Wolin
- Wollheim
- Wollheim
- Wolterstorff
- Wood
- Woodger
- Woodward
- Wrathall
- Wrathall
- Wright
- Yack
- Yasuo
- Yasuo
- Yoshimi
- Young
- Young
- Yu
- Yusa
- Zagzebski
- Zahavi
- Zahavi
- Zahavi
- Zangwill
- Zea
- Zhang
- Žižek
- Publication venue
- Publication date
- 01/01/2019
- Field of study
This chapter discusses the Rawlsian project of public reason, or public justification-based 'political' liberalism, and its reception. After a brief philosophical rather than philological reconstruction of the project, the chapter revolves around a distinction between idealist and realist responses to it. Focusing on political liberalism’s critical reception illuminates an overarching question: was Rawls’s revival of a contractualist approach to liberal legitimacy a fruitful move for liberalism and/or the social contract tradition? The last section contains a largely negative answer to that question. Nonetheless the chapter's conclusion shows that the research programme of political liberalism provided and continues to provide illuminating insights into the limitations of liberal contractualism, especially under conditions of persistent and radical diversity. The programme is, however, less receptive to challenges to do with the relative decline of the power of modern states
Constitutivism
- Author
- Achinstein
- Achinstein
- Achinstein
- Achterhuis
- Adams
- Adorno
- Adorno
- Adorno
- Adorno
- Agamben
- Ahmed
- al-Hibri
- Albert
- Alcoff
- Alexander
- Alighieri
- Allen
- Allhoff
- Allhoff
- Alpyagil
- Alston
- Ames
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- Antony
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- Armstrong
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- Arnold
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- Audi
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- Augustine
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- Auxier
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- Bach
- Baert
- Baier
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- Barad
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- Barrett
- Barwise
- Baudrillard
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- Baxley
- Beaney
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- Beaty
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- Beck
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- Bergoffen
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- Bilimoria
- Bird
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- Blake
- Blattner
- Block
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- Block
- Bloomfield
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- Bolzano
- Bondy
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- Bordo
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- Borgmann
- Botts
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- Brandt
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- Brucker
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- Bruya
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- Budd
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- Burbules
- Butler
- Butler
- Butler
- Cage
- Cahill
- Calle-Gruber
- Callicott
- Campbell
- Caputo
- Carlson
- Carnap
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- Carr
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- Chalmers
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- Chalmers
- Chalmers
- Chalmers
- Chalmers
- Chalmers
- Chastain
- Chatterjee
- Chenyang
- Chomsky
- Chomsky
- Chomsky
- Chomsky
- Chomsky
- Chomsky
- Chomsky
- Chomsky
- Chomsky
- Chomsky
- Chomsky
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- Chrisley
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- Clark
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- Clarke
- Cleveland
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- Collingwood
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- Collingwood
- Collins
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- Conant
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- Conze
- Cooper
- Cooper
- Cooper
- Copleston
- Correia
- Correia
- Correia
- Cowherds
- Cowherds
- Cowie
- Craik
- Crary
- Crisp
- Cronin
- Cronon
- Crowe
- Cua
- Currie
- Dahlstrom
- Dancy
- Dancy
- Danto
- Danto
- Danto
- Danto
- Danto
- Danto
- Darwall
- Darwin
- Dasgupta
- Dasgupta
- Dasti
- Davidson
- Davidson
- Davidson
- Davidson
- Davidson
- Davies
- Davies
- Davies
- Davies
- Davis
- Davis
- Dawkins
- de Bary
- de Bary
- De Caro
- De Caro
- de Waal
- de Waal
- Dearden
- Deleuze
- Deleuze
- Deleuze
- Denis
- Denis
- Dennett
- Dennett
- Dennett
- Dennett
- Dennett
- Dennett
- Dennett
- Dennett
- Dennett
- Depoortere
- DeRose
- deRosset
- Derrida
- Derrida
- Derrida
- Derrida
- Derrida
- Derrida
- Derrida
- Derrida
- Devall
- Devall
- DeVries
- Dewey
- Dewey
- Dewey
- Dewey
- Dewey
- Dewey
- Dewey
- Di Cesare
- Diamond
- Dickie
- Dickie
- Dilthey
- Diprose
- Dobzhansky
- Donagan
- Donovan
- Downs
- Draper
- Dravid
- Dray
- Dray
- Dray
- Dreben
- Dretske
- Dretske
- Dretske
- Dretske
- Dretske
- Dreyfus
- Dreyfus
- Dreyfus
- Dreyfus
- Dreyfus
- Dreyfus
- Dreyfus
- Dreyfus
- Dreyfus
- Driver
- Driver
- Ducasse
- Duhem
- Dummett
- Dummett
- Dummett
- Duncan
- Dupré
- Durbin
- Dutihl Novaes
- Dutton
- D’Agostino
- D’Amato
- Earman
- Earman
- Earman
- Ebbs
- Eddington
- Eliot
- Ellis
- Emerson
- Engstrom
- Eribon
- Evans
- Evernden
- Fackenheim
- Fackenheim
- Fairbairn
- Falk
- Farrell
- Faye
- Feagin
- Feenberg
- Feenberg
- Feenberg
- Feferman
- Feigl
- Fendler
- Fendler
- Ferrara
- Feyerabend
- Figal
- Fine
- Fine
- Fine
- Finlayson
- Firth
- Firth
- Flew
- Flew
- Floridi
- Fodor
- Fodor
- Fodor
- Fodor
- Fodor
- Foot
- Forst
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Fox
- Fox
- Frankena
- Frankfurt
- Franks
- Franks
- Franks
- Fraser
- Freddoso
- Freeland
- Freeland
- Freeland
- Freeman
- Frege
- Frege
- Freire
- Freire
- Freud
- Friedan
- Friedlander
- Friedman
- Friedman
- Friedman
- Friedman
- Friis
- Frost-Arnold
- Fung
- Fung
- Føllesdal
- Føllesdal
- Gadamer
- Gadamer
- Gadamer
- Gadamer
- Gadamer
- Gadamer
- Gadamer
- Gadamer
- Gadamer
- Gadamer
- Galison
- Gallie
- Gandy
- Ganeri
- Ganeri
- Garber
- Garber
- Gardiner
- Gardiner
- Gardiner
- Gardner
- Garfield
- Garrison
- Gascoigne
- Gatens
- Gaus
- Gaus
- Gaus
- Gaut
- Gaut
- George
- George
- George
- Gilligan
- Gillon
- Giunti
- Glendinning
- Glymour
- Glymour
- Godfrey-Smith
- Godlovitch
- Goehr
- Goldblatt
- Goldman
- Goldman
- Goldman
- Golomb
- Goodman
- Goodman
- Gordon
- Gordon
- Gore
- Goto-Jones
- Gould
- Gould
- Gracia
- Gracia
- Gracyk
- Gracyk
- Graham
- Graham
- Gray
- Greco
- Greco
- Green
- Gregor
- Gregory
- Grene
- Grene
- Grene
- Grice
- Grice
- Griffiths
- Griffiths
- Grondin
- Grondin
- Grondin
- Grondin
- Grosz
- Gruen
- Grünbaum
- Guarino
- Guay
- Guignon
- Guignon
- Gupta
- Guyer
- Guyer
- Guyer
- Gödel
- Gödel
- Habermas
- Habermas
- Habermas
- Habermas
- Habermas
- Habermas
- Habermas
- Habermas
- Habermas
- Habermas
- Habermas
- Habermas
- Hacker
- Hacking
- Hacking
- Hacking
- Hagberg
- Hallward
- Hamilton
- Hamilton
- Hamlyn
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- Hanke
- Hansen
- Hansen
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- Harris
- Harrison
- Hasker
- Hatab
- Haugeland
- Haugeland
- Haugeland
- Hawking
- Hawthorne
- Hawthorne
- Hawthorne
- Heal
- Hegel
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Hein
- Heisig
- Heisig
- Held
- Hellie
- Hellie
- Hellie
- Hellie
- Hempel
- Hempel
- Hempel
- Hempel
- Herman
- Herman
- Hershock
- Hershock
- Hershowitz
- Hesse
- Hesse
- Hesse
- Heyting
- Hick
- Hick
- Hick
- Hickman
- Higgins
- Hill
- Hill
- Hill
- Hintikka
- Hirsch
- Hirst
- Hirst
- Hockett
- Hoerl
- Hofweber
- Honig
- Honneth
- Honneth
- Honneth
- Honneth
- Hook
- Hooker
- hooks
- hooks
- Hookway
- Hopkins
- Horgan
- Horkheimer
- Horkheimer
- Horkheimer
- Horkheimer
- Hornsby
- Horwich
- Howard-Snyder
- Howard-Snyder
- Howson
- Hrdy
- Hu
- Hubbard
- Hull
- Hume
- Hunter
- Hursthouse
- Hursthouse
- Hursthouse
- Husserl
- Husserl
- Hylton
- Hylton
- Höffe
- Ihde
- Ihde
- Ihde
- Ihde
- Ihde
- Ihde
- Ihde
- Ihde
- Ingarden
- Irigaray
- Irigaray
- Irigaray
- Iseminger
- Ivanhoe
- Izutsu
- Izutsu
- Jackson
- Jackson
- Jackson
- James
- Jammer
- Javier-Castellanos
- Jaynes
- Jeffrey
- Jesperson
- Jesperson
- Jesperson
- Jonas
- Jonas
- Jones
- Joos
- Jost
- Juhl
- Kagan
- Kajiyama
- Kamm
- Kamm
- Kamp
- Kane
- Kant
- Kant
- Kant
- Kaplan
- Kasulis
- Kasulis
- Katz
- Katz
- Katz
- Katz
- Katz
- Kaufmann
- Kaufmann
- Kazepides
- Keane
- Kearney
- Keiji
- Keiji
- Keller
- Kelly
- Kelly
- Kenny
- Kenny
- Khoo
- Kieran
- Kieran
- Kierkegaard
- Kierkegaard
- Kim
- Kim
- King
- Kirk
- Kirloskar-Steinbach
- Kitarō
- Kitarō
- Kitarō
- Kitarō
- Kitcher
- Kitcher
- Kivy
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- Klosko
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- Margolis
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- Marquit
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- Martin
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- Minteer
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- Moran
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- Motherwell
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- Mulhall
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- Muller
- Mumford
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- Murphy
- Murphy
- Nadler
- Nagel
- Nagel
- Nancy
- Nehamas
- Neurath
- Newell
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- Newton
- Nidditch
- Nietzsche
- Nietzsche
- Nietzsche
- Nietzsche
- Nietzsche
- Nietzsche
- Noddings
- Noddings
- Nolan
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- Norton
- Nosco
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- Nozick
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- Noë
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- Oakeshott
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- Otsuka
- Owen
- Oyama
- O’Connor
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- O’Shaughnessy
- O’Shea
- O’Shea
- Papert
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- Papineau
- Parfit
- Park
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- Parker
- Parkes
- Parkes
- Passmore
- Paton
- Peacocke
- Pearl
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- Pereda
- Perrett
- Perry
- Peters
- Peters
- Peters
- Peters
- Peters
- Peters
- Peters
- Peters
- Peters
- Peters
- Peters
- Peters
- Peters
- Pettit
- Pettit
- Phillips
- Piaia
- Piaia
- Piaia
- Piercey
- Piketty
- Pinkard
- Pinkard
- Pippin
- Pippin
- Pitt
- Pitts
- Place
- Plantinga
- Plantinga
- Plantinga
- Plantinga
- Plantinga
- Plantinga
- Plantinga
- Plumwood
- Plumwood
- Pnueli
- Polanyi
- Polanyi
- Poliakov
- Popkewitz
- Popkewitz
- Popkewitz
- Popkin
- Popper
- Popper
- Popper
- Port
- Portilla
- Power
- Power
- Prado
- Press
- Preston
- Price
- Prichard
- Prior
- Pritchard
- Pritchard
- Pritchard
- Pritchard
- Psillos
- Putnam
- Putnam
- Putnam
- Putnam
- Putnam
- Putnam
- Putnam
- Putnam
- Putnam
- Putnam
- Putnam
- Putnam
- Putnam
- Pyle
- Quine
- Quine
- Quine
- Quine
- Quine
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- Quine
- Quine
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- Quine
- Quine
- Quinn
- Quinn
- Railton
- Rainer
- Rainer
- Raju
- Ramsey
- Ramsey
- Ramsey
- Rancière
- Rancière
- Rancière
- Rao
- Raven
- Raven
- Raven
- Rawls
- Rawls
- Rawls
- Rawls
- Rawls
- Rawls
- Rawls
- Rawls
- Rawls
- Rawls
- Rawls
- Rawls
- Raz
- Raz
- Raz
- Recanati
- Redhead
- Regan
- Reichenbach
- Reichenbach
- Reid
- Reiner
- Rescher
- Restall
- Rhees
- Ricoeur
- Ricoeur
- Ricoeur
- Ricoeur
- Ricoeur
- Riley
- Risser
- Robinson
- Rohkrämer
- Rolston
- Rorty
- Rorty
- Rorty
- Rorty
- Rorty
- Rorty
- Rorty
- Rorty
- Rorty
- Rorty
- Rorty
- Rosemont
- Rosen
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- Rosenberg
- Rosenberg
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- Rosenbloom
- Rosenlee
- Roski
- Ross
- Ross
- Rossi
- Routley
- Rowe
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- Ruben
- Ruben
- Rud
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- Russell
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- Russell
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- Russell
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- Ryan
- Ryle
- Ryle
- Ryle
- Saito
- Salmon
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- Sartre
- Sartre
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- Sartre
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- Savage
- Savickey
- Sayre
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- Sayre
- Scanlon
- Scanlon
- Scerri
- Schacht
- Schaffer
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- Scheffler
- Scheffler
- Scheffler
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- Schellekens
- Schellenberg
- Schier
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- Schilpp
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- Schlick
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- Schneewind
- Schneider
- Scholz
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- Schroeder
- Schrӧdinger
- Schueler
- Schutte
- Sclove
- Scruton
- Searle
- Searle
- Selfridge
- Selfridge
- Sellars
- Sellars
- Sellars
- Sellars
- Sellars
- Sen
- Sen
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- Setiya
- Shakespeare
- Shapiro
- Sharp
- Sharpe
- Shaw
- Shields
- Shiu-Hwa Tsu
- Shizuteru
- Shizuteru
- Shizuteru
- Shizuteru
- Shizuteru
- Shklar
- Shoemaker
- Shoemaker
- Shūzō
- Shūzō
- Siderits
- Siderits
- Siderits
- Sidgwick
- Sidorkin
- Siegel
- Siegel
- Siegel
- Siegel
- Silverstein
- Sim
- Simon
- Simons
- Simpson
- Singer
- Sinnerbrink
- Sircello
- Skinner
- Sklar
- Sklar
- Skyrms
- Skyrms
- Slingerland
- Sloman
- Sloman
- Sloman
- Sloman
- Sloman
- Slote
- Slote
- Slote
- Smeyers
- Smeyers
- Smeyers
- Smith
- Smith
- Smith
- Smith
- Smith
- Smuts
- Snowdon
- Snyder
- Soames
- Soames
- Soames
- Soames
- Soames
- Soames
- Soames
- Soames
- Soames
- Soames
- Sober
- Sober
- Sokal
- Sosa
- Sosa
- Spector
- Sperber
- Spirtes
- Spitz
- Staal
- Stalnaker
- Stalnaker
- Stambaugh
- Standish
- Standish
- Standish
- Standish
- Standish
- Stecker
- Stengel
- Stern
- Stern
- Stewart
- Stickney
- Stickney
- Stone
- Stone
- Stone
- Strauss
- Strauss
- Strauss
- Strauss
- Strauss
- Strauss
- Strauss
- Strauss
- Strauss
- Strauss
- Strauss
- Strauss
- Strauss
- Strawson
- Strawson
- Strawson
- Strawson
- Stroll
- Stromberg
- Stump
- Stump
- Styron
- Suppe
- Suppe
- Swinburne
- Swinburne
- Swinburne
- Swinburne
- Swinburne
- Swinburne
- Swinburne
- Tahko
- Talisse
- Tanizaki
- Tarski
- Tarski
- Tarski
- Taylor
- Taylor
- Taylor
- Taylor
- Taylor
- Taylor
- Taylor
- Taylor
- Tetsurō
- Tetsurō
- Thom
- Thompson
- Thomson
- Thomson
- Thomson
- Thomson
- Thomson
- Tilghman
- Timmons
- Todd
- Todd
- Tola
- Tomasi
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- Trianosky
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- Verbeek
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- Warfield
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- Wartenberg
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- Watson
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- Weber
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- Williams
- Williams
- Williams
- Williams
- Williams
- Williams
- Williams
- Williams
- Williams
- Williams
- Williams
- Williamson
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- Wilson
- Wilson
- Wilson
- Wimsatt
- Wimsatt
- Wimsatt
- Winch
- Windelband
- Winner
- Wittgenstein
- Wittgenstein
- Wittgenstein
- Wittgenstein
- Wittgenstein
- Wittgenstein
- Wittgenstein
- Wittgenstein
- Wittgenstein
- Wittgenstein
- Wittgenstein
- Wittgenstein
- Wittgenstein
- Wolff
- Wolin
- Wolin
- Wollheim
- Wollheim
- Wolterstorff
- Wood
- Woodger
- Woodward
- Wrathall
- Wrathall
- Wright
- Yack
- Yasuo
- Yasuo
- Yoshimi
- Young
- Young
- Yu
- Yusa
- Zagzebski
- Zahavi
- Zahavi
- Zahavi
- Zangwill
- Zea
- Zhang
- Žižek
- Publication venue
- Publication date
- 01/01/2019
- Field of study
A brief explanation and overview of constitutivism
Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial
- Author
- Abano Nenette
- Abbdul-saheb Mudhar
- Adedoyin Temi
- Adell Victoria
- Adesina Tolu
- Adie Katja
- Adil-Smith Jennifer
- Ahmad Nasar
- Ahmed Ashraf
- Ahmed Iman
- Al-Mayhani Talal
- Al-Shahi Salman Rustam
- Al-Shahi Salman Rustam
- Alam Mohammad Irfan
- Albazzaz Mo
- Ali Ali
- Alipio Francis
- Allen Christopher
- Allison Joanna
- Amey Isobel
- Amis Elaine
- Amlani Sageet
- Amoils Shannon
- Amor Kelly
- Anderson Rosemary
- Andole Sreeman
- Anjum Talat
- Ankolekar Sandeep
- Annamalai Arunkumar
- Anthony Alpha
- Anversha Ajmal
- Anwar Ijaz
- Anwar Sajjad
- Appleton Jason
- Argandona Lucia
- Armitage Jane
- Ashton Amy
- Atkinson Natalie
- Auld Grace
- Avis Joanne
- Aweid Basaam
- Ayres Georgina
- Azhar Khalid
- Bagnall Caroline
- Baig Farrukh
- Baigent Colin
- Bailey Duncan
- Baird Yolanda
- Bakawala Rehana
- Baker John
- Baker Pauline
- Balazikova Olga
- Balian Linda
- Baliga Vidya
- Balitska Olesia
- Ball Julie
- Ball Margaret
- Ballantine Robert
- Bamford John
- Banaras Azra
- Barber Mark
- Barbon Emma
- Barker James
- Barr Charlotte
- Barrie Elizabeth
- Barron Luke
- Barry Adrian
- Bateman Gavin
- Bates Michelle
- Bathula Rajaram
- Battersby-Wood Emma
- Bayliss Pauline
- Beadle Hannah
- Bearne Helen
- Beaty Teresa
- Beaves Emily
- Bell Angela
- Bell Jo
- Bell Murdina
- Bellfield Ruth
- Beranova Eva
- Bergin Adrian
- Bhakri Harbens
- Bhalla Ajay
- Bharaj Kiranjit
- Bhargava Maneesh
- Bhaskaran Biju
- Bhatnagar Priya
- Bhatnagar Priya
- Birchall Kathryn
- Birns Jonathan
- Black Toby
- Blades Alex
- Blair Caroline
- Blair Caroline
- Blair Gordon
- Blane Sujata
- Blank Catrin
- Blight Adrian
- Board Joanne
- Board Sarah
- Bokhari Maria
- Bond Kirsty
- Bowring Angela
- Boxall Cherish
- Breeds Joanna
- Brew Helen
- Brezitski Maria
- Bridger Hayley
- Brodie Fiona
- Brotherton Lucy
- Broughton David
- Brown Claire
- Brown Ellen
- Brown Pauline
- Brown Sarah
- Bruce David
- Buchanan David
- Buck Amanda
- Buckle Steve
- Buckle Steve
- Buckley Clare
- Bunea George
- Burger Ilse
- Burgess Laura
- Burgess Seona
- Burssens Evelyne
- Butler Adrian
- Butler Donna
- Butler Rebecca
- Butterworth-Cowin Nicola
- Button Denise
- Buxton Jean
- Byrne Anthony
- Cageao Julie
- Caine Sarah
- Campbell Robert
- Carpenter Michael
- Carpio Racquel
- Carrie Johanna
- Cassidy Tim
- Causley Chelsea
- Chadbourn Indra
- Chadha Dinesh
- Chamberlain Angela
- Chan kelly
- Chandrakumar Aberami
- Chapman Kath
- Chapman Nicola
- Charles Bethan
- Chatterjee Kausic
- Chaudhry Afnan
- Chauhan Meena
- Chenna Srikanth
- Cherian Suja
- Cheripelli Bharath Kumar
- Chopra Neha
- Choulerton James
- Choy Lillian
- Clarke Brian
- Clarke Caroline
- Clarke Judith
- Clarke Natasha
- Clarke Rebecca
- Clarke Samantha
- Clarkson Emma
- Clay Caroline
- Clayton Susan
- Clayton-Evans Lisa
- Cluckie Gillian
- Cochrane Helen
- Codd Laura
- Cohen David
- Collins Kayleigh
- Connor Lynda
- Constantin Carmen
- Cook Angela
- Cooper Martin
- Copeland Claire
- Cosier Tracey
- Courtauld Gillian
- Couser Mandy
- Coward Lucy
- Cowie Linda
- Cox Chantel
- Cox Chloe
- Cox Penelope
- Crabtree Karen
- Crawford Pam
- Crawford Susan
- Creeden Robyn
- Crisp Sarah
- Cronin Julie
- Crook Luci
- Crosbie Caroline
- Crouch Nichola
- Crown Rachel
- Crowther Hannah
- Cuddy Sarah
- Cuenoud Larissa
- Cullen Claire
- Culmsee Charlotte
- Cunningham James
- Cunningham Mishell
- Cvoro Vera
- Dacey Lynne
- Dakin Katy
- Dallol Bander
- Dangri Puneet
- Datta Prabal
- Davey Richard
- David Anette
- David Owen
- Davies Caroline
- Davies Ruth
- Davies Silvie
- Davis Fiona
- Davis Michelle
- Day Nicola
- Dayal Nilofer
- De Berker Henry
- Deary Ann
- Denic Hayley
- Dennis Martin
- Dennis Martin S
- Denniss Carol
- Devine Joseph
- Devitt Nicola
- Dewar Richard
- Dhakal Mahesh
- Dhar Saikat
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- Dickson Christine
- Dima Sofia
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- Dixon Lynn
- Dobson Tracey
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- Dodd Emily
- Doherty Mandy
- Doherty Mandy
- Donaldson Denise
- Donnelly Richard
- Doubal Fergus
- Dow Lindsey
- Downham Susan
- Doyle Clare
- Doyle Donna
- Drever Jonathan
- du Plessis Johann C
- du Plessis Johannes
- Dube Judith
- Duberley Stephen
- Dunn Linda
- Dunne Karen
- Durairaj Ramesh
- Durman Helen
- Dutta Dipankar
- Dynan Kevin
- Edwards Mandy
- Egerton Shuna
- Eglinton Charlotte
- Eglinton Charlotte
- El Tawil Salwa
- Elfandi Khaled
- Elliot Jennifer
- Elliott Emma
- Ellis Sam
- Emberson Jonathan
- Emsley Hedley
- England Timothy
- Epstein Daniel
- Erande Renuka
- Erumere Esther
- Esisi Bernard
- Esisi Bernard
- Esson Derek
- Esson Derek
- Evans Rachel
- Evans Sue
- Eveson David
- Ewing Jordan
- Fathima Razik
- Fawcett Michelle
- Feerick Shez
- Fennelly Ruth
- Ferdinand Phillip
- Findlay Paul
- Finlay Sarah
- Finney Kay
- Fitzell Pauline
- Fitzsimmons Paul
- Fletcher Glyn
- Fletcher Jo
- Fong Rosanna
- Foot Jayne
- Foote Leanne
- Ford Gary
- Foster Eliza
- Fotherby Ken
- Fox Charlotte
- Francia Nina
- Francis Jobbin
- Fraser Ruth
- Fraser Ruth
- Fuller Tracy
- Fulton Ailsa
- Furnace Jacqueline
- Gadapa Naveen
- Gainard Glyn
- Gainsborough Nicola
- Gallagher Jill
- Gallagher Louise
- Gallifent Rachel
- Gamble Ed
- Garcia Tatiana
- Gardener Léjeune
- Garfield-Smith Joanne
- Garside Mark
- Gartrell Imogen
- Gascoyne Rachel
- Gattringer Thomas
- Gautam Nikki
- Gaylard Jane
- Gbadamoshi Lukuman
- Geraghty Olivia
- Ghaly George
- Ghatala Rita
- Ghosh Sandip
- Giallombardo Elio
- Gilham Ellie
- Gilmour Danielle
- Gilzeane Nicola
- Glass Jon
- Gleave Laura
- Glover Rachel
- Godfrey Margi
- Goff Anita
- Goorah Neetish
- Gott Valerie
- Gow Heather
- Graham Carol
- Graham Ruth
- Gray Jane
- Green Carole
- Greenwood Richard
- Gregory Bindu
- Greig Jill
- Grimwood Gemma
- Grocott Jeanette
- Grue Rebecca
- Gulliver Diane
- Guo Fenglin
- Gupwell Karin
- Guthrie Lucy Belle
- Guy Helen
- Guyler Paul
- Hague Adam
- Haider Syed
- Hairsine Brigid
- Hakim Eluzai
- Hall Andrea
- Halse Omid
- Handley Dominic
- Hann Gail
- Hannon Niamh
- Hansen Christian
- Haque Mohammad
- Hardwick Anne
- Harkness Kirsty
- Harrington Frances
- Harrington-Davies Yasmin
- Harrison Louise
- Harrison Melanie
- Harrison Thomas
- Harston George
- Harvey Kirsten
- Harvey Miriam
- Hassan Ahamad
- Hassan Hardi
- Havard Diane
- Hayes Anne
- Hayhoe Helen
- Hayman Rachel
- Hays Carole
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- Hedstrom Amanda
- Hedstrom Amanda
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- Howard Joanne
- Howard Peter
- Howcroft Deborah
- Howe Jo
- Huang Xuya
- Huggett Isabel
- Hughes Chloe
- Hughes Claire
- Hughes Tom
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- Humphries Fiona
- Hunt Benjamin
- Hunt Nicholas
- Hunter Annemarie
- Hunter Neil
- Hurford Frances
- Hurley Jennifer
- Hussain Malik
- Hutchison Aidan
- Hyams Benjamin
- Hyatt Lisa
- Imam Javed
- Ingham Andrea
- Ingram Tanya
- Innes Karen
- Iqbal Arshi
- Iqbal Mohammad Shazad
- Irvine Janice
- Ispoglou Sissy
- Ivatts Simone
- Jackson Benjamin
- Jackson Linda
- Jagger Jenny
- Jagpal Baljit
- James Ali
- James Claire
- James Martin
- Jarapa Rowilson
- Jarrett David
- Jeffs Carol
- Jelley Benjamin
- Jenkins Colin
- Jennings-Preece Karla
- Jeyaraj Naomi
- Jha Ratneshwari
- Jinks Emma
- Johnes Mary
- Johnson Sharon
- Jones Ifan
- Jones Ifan
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- Jones Rachael
- Jones Stephanie
- Jones Terry
- Jones Val
- Jordan Carla
- Jose Deepa
- Jose Josin
- Joshi Yogish
- Joshi Yogish
- Joyson Anu
- Jupp Becky
- Justin Frances
- Kakar Puneet
- Kalathil Latheef
- Kalladka Dheeraj
- Kamara Christine
- Kambafwile Mary
- Kane Ingrid
- Kar Arindam
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- Keenan Samantha
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- Kennedy Kate
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- Kerin Lourda
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- Kerr Gillian
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- Khan Mohammad
- Khan Shagufta
- Khan Usman
- Khan Uzma
- Kibutu Faith
- King Sam
- Kingwell Hayley
- Kini Manohar
- Klaasen Katrina
- Knops Kerstin
- Krishnamoorthy Shrivakumar
- Krishnamurthy Ramesh
- Krishnamurthy Vinodh
- Krishnan Kailash
- Krishnan Manju
- Krommyda Magdalini
- Kullane Sagal
- Kumar Balakrishna
- Kumar Pradeep
- Kunhunny Swapna
- Lam Man Yee
- Lambert Caroline
- Landers Geraldine
- Langhorne Peter
- Lasserson Daniel
- Latter Laura
- Law Zhe
- Lawrence Tara
- Lawson Heidi
- Leason Sandra
- Lee Stephanie
- Leggett Jacqui
- Lenti Giulia
- Lerpiniere Christine
- Lerpiniere Christine
- Licenik Radim
- Lindert Ralf
- Little Victoria
- Littleton Edward
- Ljubez Anja
- Loganathan Thayalini
- Longland Barbara
- Lopez Paula
- Lovelock Caroline
- Lowe Gordon
- Lucas Linda
- Lucas Suzanne
- Luder Robert
- Lyjko Sue
- Maanoosi Mehran
- Maatouk Ahmad
- Macaden Ashish
- MacInnes Brian
- MacLennan Beverly
- Macleod Malcolm
- MacLeod Mary
- MacLiver Linda
- MacRaild Allan
- Maddula Mohana
- Madigan Barbara
- Maguire Holly
- Maguire Stuart
- Maiden Susan
- Majis Arshad
- Majmudar Nikhil
- Makawa Linetty
- Mangion David
- Manning Lisa
- Manoj Aravind
- Mardania Rina
- Marigold James Richard
- Markova Skarlet
- Marks Katherine
- Marsden Tracy
- Marshall Sally
- Martin Irene
- Mashate Sheila
- Mason Cathy
- Mate Abhijit
- Mathieson Philip
- Matias Oliver
- Matthews Christopher
- Maund Bev
- McAlpine Christine
- McArdle Damian
- Mcauley Sean
- McCann Stephanie
- McCarron Mark
- McClelland Beverley
- McCormick Katrina
- McCormick Katrina
- McDonald Shanni
- McDonald Susan
- Mcgee Joanne
- McGhee Caroline
- McGill Connor
- McGrath Aileen
- McIlmoyle James
- McKee Jacqueline
- McLoughlin Alison
- McVerry Ferghal
- Mead Denise
- Mead Gillian
- Meir Julie
- Menon Nisha
- Mercer Lily
- Metcalf Kneale
- Miller Keniesha
- Miller Richard
- Milligan Josette
- Minks David
- Minks David P.
- Miriam Skelton
- Mistri Amit
- Mitchell Jennifer
- Mitra Dipayan
- Mitra Dipayan
- Mohammed Niaz
- Mohd Nor Azlisham
- Mokoena Betty
- Moores Andrew
- Moqsith Mohammed
- Morell Jordi
- Moreton Fiona
- Morgan Debbie
- Moroney Helen
- Morse Bethan
- Moseley Sally
- Motherwell Nichola
- Moynihan Barry
- Mpelembue Mushiya
- Mudd Paul
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- Muir Keith
- Mukherjee Indranil
- Murali Elodie
- Murphy Peter
- Murray Gordon D
- Musarrat Kashif
- Myint Min
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- Naing Zin
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- Nasar Mohammad
- Nasim Ashraf
- Naylor Charde
- Needle Ann
- Nelson Sandra
- Newby David E
- Newton Sophie
- Ng Kheng Xiong
- Ngo David
- Nguyen Vinh
- Ngwako Mmua
- Ni Hlaing
- Nicholas Paul
- Nicolson Anne
- Niranchanan Rangah
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- Njoku Kelechi
- Nott Claire
- Nott Claire
- Nozedar Tarn
- Nyabadza Sheila
- O'Brien Eoin
- O'Brien Richard
- O'Brien Richard
- O'Connell Susan
- O'Loughlin Victoria
- O'Reilly Joanna
- O'Toole Sarah
- OConnell Janice
- Oji Nnebuife
- Orath Prabakaran Rajalakshmi
- Orefo Chukwuka
- Orugun Enoch
- Osborn Mairead
- Osborne Emily
- Oshodi Anne
- Osman Ahmed
- Ovington Catherine
- Owings Paula
- Owoyele Emmanuelle
- Owusu-Agyei Peter
- Pai Yogish
- Palmer Jeb
- Papavasileiou Vasileios
- Parakramawansha Ruwan
- Parker Richard
- Parry Anthea
- Parry-Jones Adrian
- Pasco Kath
- Patel Bhavini
- Patel Champa
- Patel Farzana
- Patel Krishna
- Patterson Chris
- Paulton Ruth
- Pawley Corinne
- Peixoto Cassilda
- Penge Justin
- Perez Jane
- Perfitt Rebekah
- Perkins Charlotte
- Perry David
- Perry Jack
- Persad Nicola
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- Pettitt Kerry
- Phiri Duke
- Pitt-Ford Alexandra
- Pitt-Kerby Tressy
- Plewa Catherine
- Poku Philip
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- Poultney Una
- Pound Susan
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- Price Fiona
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- Punter Martin
- Pusalkar Aparna
- Putterill Janet
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- Quinn Outi
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- Raghunathan Senthil
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- Rashmi Sindhu
- Ravenhill Garth
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- Reckless Ian
- Reddan Julie
- Reddan Julie
- Redgrave Jessica
- Redjep Ozlem
- Remegoso Alda
- Richard Bella
- Richards Emma
- Rinkel Gabriel
- Roberts Josh
- Robinson Matthew
- Robinson Naomi
- Rodgers Alicia
- Rodrigues Mark A
- Rodriguez Aryelly
- Roffe Christine
- Roffe Jack
- Roganova Tatjana
- Rogers Emily
- Rogers Gill
- Rojas Javier
- Ross Sarah
- Roughan Caroline
- Rudd Tony
- Rudenko Hannah
- Saada Janak
- Saastamoinen Kari
- Sajid Mahmud
- Sakka Eleni
- Salehin Maqsud
- Salek-Haddadi Afraim
- Salih Isam
- Sally Moore
- Sandercock Peter A G
- Sangombe Mirriam
- Sangster Graeme
- Sanyal Ranjan
- Sarah Procter
- Sarah Procter
- Sattar Naweed
- Sattar Saira
- Saulat Afaq
- Saulat Afaq
- Schofield Christine
- Schulz Ursula
- Schumacher Natasha
- Schwarz Stefan
- Seagrave Samantha
- Sekaran Lakshmanan
- Sesay Juliana
- Sethuraman Sakthivel
- Shackcloth Daniela
- Shah Alex
- Shah Sweni
- Shahmehri Shahrzad
- Sharma Nikhil
- Sharpe Simon
- Shaw Kelly Marie
- Shaw Louise
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- Shekhar Raj
- Shelton Faye
- Shinh Naval
- Shread Ian
- Shukla Avani
- Siddegowda Prasad
- Siddiq Muhammad
- Siddiqui Amber
- Siddiqui Anwer
- Sigsworth Andrew
- Simon Rohan
- Sims Don
- Singh Arun
- Sinha Devesh
- Skinner Helen
- Slade Peter
- Smart Amanda
- Smith Andrew
- Smith Fiona
- Smith Gemma Marie
- Smith Simon
- Smith Wilma
- Smyth Nigel
- Spencer Jayne
- Sprigg Nikola
- Sprigg Nikola
- Srinivasan Meena
- Stafford Samantha
- Stafford Samantha
- Stanners Andrew
- Steele Amy
- Stephen Jacqueline
- Stephens Claire
- Stevens Angela
- Stevens Stephanie
- Stevenson Sarah
- Stewart Kelvin
- Stocks Kathy
- Stone Andrew
- Storton Sharon
- Strain David
- Subramonian Santhosh
- Sudlow Cathie
- Sudlow Cathie L M
- Sukdeo Varthi
- Sullivan Frank
- Sultan Sulaiman
- Suttling Anne
- Sutton Claire
- Sutton Patrick
- Sutton Victoria
- Sword Jane
- Sykes Lucy
- Symonds Stuart
- Szabo Susan
- Tallantyre Emma
- Tanate Alfonso
- Tandy Jane
- Tate Margaret
- Tauro Suzanne
- Tayler Michelle
- Taylor Pat
- Taylor Vicky
- Teal Rachel
- Temple Natalie
- Thant Hlaing
- Thavanesan Kamy
- Thomas Isobel
- Thomas Kelly
- Thomas Philip
- Thomas Sarah
- Thompson Philip
- Thompson Susan
- Thompson Teresa
- Thompson-Jones Helen
- Thomson Audrey
- Thornthwaite Sarah
- Thorpe Kevin
- Tilley Victoria
- Tiwari Divya
- Tomlin Dawn
- Tomlinson Benjamin
- Treadwell Shelley
- Tribbeck Michele
- Trippier Sarah
- Triscott Claire
- Triscott Claire
- Tryambake Dinesh
- Tucker Laura
- Tucker Susan
- Turfrey Jennifer
- Tysoe Sharon
- Ullah Khalil
- Valentine Stacey
- van Someren Chloe
- Varquez Resti
- Vasileiadis Evangelos
- Vassallo Joseph
- Venter Marius
- Veraque Emelda
- Verrion Anna
- Vettimootal Johnson Venetia
- Vickers Carinna
- Walford Jamie
- Walker Allan
- Walker Marion
- Walker Pauli
- Walker Susannah
- Wallace Aine
- Wallace Rebecca
- Wallace Rebecca
- Walstow Deborah
- Walter Deborah
- Walters Ashleigh
- Wani Mushtaq
- Ward Deborah
- Wardlaw Joanna M
- Watchurst Caroline
- Waterfield Kelly
- Waterfield Kelly
- Watson Fran
- Waugh Dean
- Webb Tom
- Webber Adam
- Webster Timothy
- Weinling Marie
- Weir Nic
- Weir Pauline
- Welch Angela
- Werring David
- Werring David J
- Whitcher Alison
- White James
- White Julie
- White Philip M
- White Susan
- Whiteley William
- Whiteley William N
- Whiteman Jessica
- Whiteman Jessica
- Whiting Robert
- Whittamore Katherine
- Wiggam Ivan
- Wilding Peter
- Wilkes Gwendoline
- Wilkinson Mark
- Willberry Angela
- Williams Carol
- Williams Rebecca
- Williams-Yesson Barbara
- Willmot Mark
- Wilson David
- Wilson Duncan
- Wilson Jenny
- Wilson Lisa
- Wilson Sarah
- Wiltshire Alison
- Wood Diane
- Wood Edith
- Wood Lisa
- Woodward Stephen
- Wright Fiona
- Wroath Belinda
- Wynter Inez
- Yadava Rajendra
- Yip Brigitte
- Young Andrew
- Zachariah George
- Zahoor Tajammal
- Zoe Mellor
- Publication venue
- 'Elsevier BV'
- Publication date
- 22/05/2019
- Field of study
Background
Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy. Brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases (such as cerebral microbleeds) are associated with greater risks of recurrent intracerebral haemorrhage. We did subgroup analyses of the RESTART trial to explore whether these brain imaging features modify the effects of antiplatelet therapy
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution.
- Author
- Abbosh Christopher
- Abbosh Christopher
- Abbosh Christopher
- Adams Haydn
- Adams Haydn
- Aerts Hugo J. W. L.
- Aerts Hugo JWL
- Ahmad Tanya
- Ahmad Tanya
- Ahmed Asia
- Ahmed Asia
- Aissa Assma Ben
- Akarca Ayse U
- Akarca Ayse U
- Al Bakir Maise
- Al Bakir Maise
- Alzetani Aiman
- Amadi Anita
- Ambrose Lyn
- Anand Girija
- Anand Girija
- Aranda Marie
- Asante-Siaw Julius
- Ashish Chandra
- Attanoos Richard
- Attanoos Richard
- Attard Gert
- Azcarate Leire
- Baijal Shobhit
- Bakar Yusura
- Bakir Maise Al
- Bancroft Hollie
- Bancroft Hollie
- Beck Stephan
- Begum Sharmin
- Bell Harriet
- Bell Harriet
- Bellamy Mary
- Bennett Jonathan
- Bhayani Harshil
- Bi Wenya Linda
- Biankin Andrew
- Biggs Jennifer
- Birkbak Nicolai J
- Birkbak Nicolai J.
- Bishop Paul
- Blackhall Fiona
- Blackhall Fiona
- Blackhall Fiona
- Booton Richard
- Borg Elaine
- Borg Elaine
- Borg Elaine
- Bosshard-Carter Leticia
- Bova Steve
- Bowman Alex
- Brady Ged
- Brandner Sebastian
- Brenton James
- Bridgewater John
- Buchan Keith
- Buderi Silviu
- Bury Jonathan
- Caldas Carlos
- Califano Raffaele
- Campbell Peter
- Carnell Dawn
- Carter Louise
- Chambers Antony
- Chambers Tim
- Chambers Tim
- Chaturved Anshuman
- Chavan Hema
- Chee Serena
- Chemi Francesca
- Chetty Mahendran
- Chetty Mahendran
- Choudhary Junaid
- Chowdhury Simon
- Cluroe Alison
- Cockcroft Peter
- Collard Martin
- Colloby Peter
- Conibear John
- Constantin Tudor
- Constatin Tudor
- Costa Marta
- Crosbie Phil
- Crosbie Phil
- Czyzewska-Khan Justyna
- Czyzewska-Khan Justyna
- Danson Sarah
- Davies Helen
- Davies Helen
- De Sousa Paulo
- Denner Tamara
- Dentro Stefan
- Dessimoz Christophe
- Devaraj Anand
- Dhomen Nathalie
- Dive Caroline
- Dive Caroline
- Dive Caroline
- Djearaman Madava
- Doran Helen
- Edwards Alison
- Edwards John
- Eeles Ros
- Elena Cufari Maria
- Elgar Greg
- Elgar Greg
- Endozo Raymondo
- Enver Tariq
- Escudero Mickael
- Evison Matthew
- Ezhil Veni
- Ezhil Veni
- Falzon Mary
- Falzon Mary
- Falzon Mary
- Farrelly Laura
- Feeney Sarah
- Fennell Dean
- Fennell Dean
- Fennell Dean A.
- Fennessy Fiona M.
- Finch Jonathan
- Fisher Patricia
- Fitzgerald Rebecca
- Flanagan Adreinne
- Fontaine Eustace
- Forster Martin
- Forster Martin D.
- Foster Chris
- Fraioli Francesco
- Fraser Sioban
- Furness Andrew
- Ganguly Apratim
- George Jeremy
- Georgiou Andy
- Gilbertson Richard
- Gishen Faye
- Goh Gerald
- Goldman Jacki
- Gomersall Lesley
- Gomersall Lesley
- Gorman Pat
- Gosney John
- Gower Nicole
- Graca Sofia
- Green Sophie
- GrÖnroos Eva
- GrÖnroos Eva
- Gulati Sakshi
- Hackshaw Allan
- Hackshaw Allan
- Hackshaw Allan
- Hafez Dina
- Hamilton Morag
- Harrison David
- Harrison Phil
- Hartley John A
- Hartley John A
- Hayward Martin
- Hayward Martin
- Hector Gemma
- Herrero Javier
- Herrero Javier
- Hiley Crispin
- Hiley Crispin
- Hill Jennifer
- Hochauser Daniel
- Horey Tracey
- Horswell Stuart
- Hynds Robert E
- Idries Faiza
- Iles Natasha
- Iles Natasha
- Irvin-sellers Melanie
- Irvin-sellers Melanie
- Ismail Babikir
- Ismail Babikir
- Jamal-Hanjani Mariam
- Jamal-Hanjani Mariam
- Jamal-Hanjani Mariam
- Janes Sam M
- Janes Sam M
- Jimenez-Linan Merche
- Johnson Benjamin
- Johnson Diana
- Johnson Diana
- Jordan Simon
- Joseph Leena
- Joseph Leena
- Joshi Kroopa
- Kadiri Salma
- Kadiri Salma
- Kareht Stephanie
- Keerio Allah Dino
- Kerr Amy
- Kerr Amy
- Kerr Keith
- Kerr Keith
- Khan Sajid
- Khan Sajid
- Kirkizlar Eser
- Kitsanta Yota
- Kolvekar Shyam
- Kolvekar Shyam
- Kornaszewska Malgorzata
- Kornaszewska Malgorzata
- Krebs Matt
- Krysiak Piotr
- Kwayie Angela
- Langman Gerald
- Langman Gerald
- Langman Gerald
- Larkin James
- Lau Kelvin
- Lawrence David
- Lawrence David
- Laycock Joanne
- Laycock Joanne
- Le Quesne John
- Le Quesne John
- Lederman Jonathan
- Lee Siow Ming
- Lee Siow Ming
- leek Angela
- Lester Jason
- Lester Jason
- Light Teresa
- Lim Eric
- Lin C. Jimmy
- Lock Sara
- Lock Sara
- Loda Massimo
- Lok Chi-wah
- Lowe Helen L
- Lowe Helen L
- Lynch Joanna
- Lynch Mark
- MacKenzie Mairead
- Marafioti Teresa
- Marafioti Teresa
- Marafioti Teresa
- Marais Richard
- Marie Quinn Anne
- Marshall Hilary
- Martinson Luke
- Martinson Luke
- Martinson Luke
- Mashinga Hillaria
- Matthews Nik
- Matthews Nik
- Matthews Sue
- Maughan Tim
- McDermott Ultan
- McGranahan Nicholas
- McGranahan Nicholas
- McKenzie Mairead
- McNeish Iain
- Mendes Ruheena
- Mensah Natalie
- Middleton Gary
- Middleton Gary
- Middleton Gary
- Miller Joy
- Mitchison Miriam
- Mitter Richard
- Monteiro William
- Moore David
- Moore David
- Moore David A
- Moore Katrina
- Morgan Fiona
- Moss Stuart
- Murugaesu Nirupa
- Naidu Babu
- Naidu Babu
- Naidu Babu
- Naik Ashwini
- Naik Ashwini
- Nakas Apostolos
- Nakas Apostolos
- Navani Neal
- Nelson Louise
- Ngai Yenting
- Ngai Yenting
- Nicholson Andrew G
- Nicolson Marianne
- Nicolson Marianne
- Nonaka Daisuke
- Novasio Juliette
- Novelli Marco
- Novelli Marco
- Nye Emma
- Oien Karin
- Olisemeke Bernard
- Ottensmeier Christian
- Ottensmeier Christian
- Oukrif Dahmane
- Oukrif Dahmane
- Palmer Shirley
- Panagiotopoulos Nikolaos
- Panagiotopoulos Nikolaos
- Papadatos-Pastos Dionysis
- Parker Peter
- Phillimore Ben
- Pierce Jackie
- Postmus Pieter
- Prakash Vineet
- Prakash Vineet
- Primrose Lindsay
- Proctor Ian
- Proli Chiara
- Provenzano Elena
- Quesne John Le
- Quezada Sergio
- Quezada Sergio
- Quezada Sergio A
- Quinn Anne Marie
- Quinn Anne Marie
- Rabinowitz Matthew
- Rabinowitz Matthew
- Rammohan Kendadai
- Rathinam Sridhar
- Rathinam Sridhar
- Raubenheimer Hilgardt
- Remmen Hardy
- Remmen Hardy
- Rice Alexandra
- Riley Joan
- Riley Joan
- Riley Joan
- Rogan Jane
- Ronquillo John Carlo
- Rosenthal Rachel
- Rosenthal Rachel
- Rothwell Dominic G
- Rowan Andrew
- Rowan Andrew
- Russell Peter
- Russell Peter
- Salari Raheleh
- Salari Raheleh
- Schmid Peter
- Schwarz Roland F
- Shackcloth Michael
- Shafi Seema
- Shafi Seema
- Shah Rajesh
- Shah Rajesh
- Sharp Abby
- Shaw Emily
- Shaw Jacqui
- Shaw Jacqui A
- Shaw Jacqui A
- Sheaff Michael
- Shiu Kai-Keen
- Simeon Celia
- Sinclair Ron
- Smith Amy
- Smith Elaine
- Smith Sean
- Sottoriva Andrea
- Spicer James
- Sponer Nicole
- Sponer Nicole
- Stares Mark
- Sterling Caroline
- Stewart Aengus
- Stewart Aengus
- Stewart Grant
- Stone Paddy
- Stone Richard Kevin
- Summers Yvonne
- Summers Yvonne
- Summers Yvonne
- Suvarna Kim
- Swanton Charles
- Swanton Charles
- Swanton Charles
- Szallasi Zoltan
- Tanchel Bruce
- Tavare Simon
- Tavares Barbosa Monica
- Taylor Joanne
- Taylor Magali
- Taylor Paul
- Thakrar Ricky
- Thakrar Ricky
- Thomas Anne
- Tomlinson Ian
- Tookman Adrian
- Trevisan Giorgia
- Trotter Simon
- Trotter Simon
- Tugwood Jonathan
- Turajlic Samra
- Turajlic Samra
- Turajlic Samra
- Van Loo Peter
- Van Loo Peter
- Van Loo Peter
- Veeriah Selvaraju
- Veeriah Selvaraju
- Verjee Azmina
- Waddington Rachael
- Walczak Henning
- Walter Harriet
- Ward Sophia
- Ward Sophia
- Watkins Thomas B K
- Watkins Thomas B K
- Watts Colin
- Webb Joanne
- Webb Joanne
- Wilcox Maggie
- Wilcox Maggie
- Wilson Gareth
- Wilson Gareth A.
- Wilson Rodelaine
- Wong Yien Ning Sophia
- Xu Hang
- Zambrana Francisco
- Zimmermann Bernhard
- Zimmermann Bernhard G.
- Publication venue
- Nature
- Publication date
- 01/01/2017
- Field of study
The early detection of relapse following primary surgery for non-small-cell lung cancer and the characterization of emerging subclones, which seed metastatic sites, might offer new therapeutic approaches for limiting tumour recurrence. The ability to track the evolutionary dynamics of early-stage lung cancer non-invasively in circulating tumour DNA (ctDNA) has not yet been demonstrated. Here we use a tumour-specific phylogenetic approach to profile the ctDNA of the first 100 TRACERx (Tracking Non-Small-Cell Lung Cancer Evolution Through Therapy (Rx)) study participants, including one patient who was also recruited to the PEACE (Posthumous Evaluation of Advanced Cancer Environment) post-mortem study. We identify independent predictors of ctDNA release and analyse the tumour-volume detection limit. Through blinded profiling of postoperative plasma, we observe evidence of adjuvant chemotherapy resistance and identify patients who are very likely to experience recurrence of their lung cancer. Finally, we show that phylogenetic ctDNA profiling tracks the subclonal nature of lung cancer relapse and metastasis, providing a new approach for ctDNA-driven therapeutic studies
Philosophy of action
- Author
- Achinstein
- Achinstein
- Achinstein
- Achterhuis
- Adams
- Adorno
- Adorno
- Adorno
- Adorno
- Agamben
- Ahmed
- al-Hibri
- Albert
- Alcoff
- Alexander
- Alighieri
- Allen
- Allhoff
- Allhoff
- Alpyagil
- Alston
- Ames
- Améry
- Anderson
- Ankersmit
- Ankersmit
- Ankersmit
- Ankersmit
- Ankersmit
- Annas
- Anscombe
- Anscombe
- Anscombe
- Antony
- Apel
- Apel
- Apel
- Apple
- Aquinas
- Aquinas
- Archambault
- Arendt
- Arendt
- Armstrong
- Armstrong
- Armstrong
- Armstrong
- Armstrong
- Arnold
- Arnold
- Aschheim
- Audi
- Audi
- Augustine
- Augustine
- Aune
- Aurobindo
- Austin
- Austin
- Auxier
- Ayer
- Ayer
- Ayer
- Ayer
- Bach
- Baert
- Baier
- Baker
- Baker
- Baker
- Bales
- Ball
- Ball
- Barad
- Barnes
- Barnes
- Baron
- Barrett
- Barwise
- Baudrillard
- Baumgartner
- Baxley
- Beaney
- Beaney
- Beardsley
- Beardsley
- Beardsley
- Beaty
- Beauvoir
- Beauvoir
- Beauvoir
- Beck
- Becker
- Becker
- Bekoff
- Bellah
- Benjamin
- Bennett
- Bennett
- Bennett
- Bennett
- Bergoffen
- Berleant
- Berlin
- Bernasconi
- Bernstein
- Bernstein
- Besley
- Besley
- Bilimoria
- Bird
- Bishop
- Blake
- Blattner
- Block
- Block
- Block
- Bloomfield
- Bloor
- Boas
- Boden
- Boden
- Boden
- Boler
- Bolzano
- Bondy
- Bookchin
- Bordo
- Bordwell
- Borgmann
- Botts
- Bourdieu
- Bovens
- Bowles
- Boyd
- Bradshaw
- Braithwaite
- Brand
- Brandis
- Brandom
- Brandom
- Brandt
- Bratman
- Braudy
- Bridges
- Bridges
- Brink
- Broome
- Brown
- Brown
- Brown
- Brown
- Brown
- Brucker
- Bruner
- Brunner
- Bruya
- Bryson
- Bubner
- Budd
- Budd
- Bunge
- Burbules
- Butler
- Butler
- Butler
- Cage
- Cahill
- Calle-Gruber
- Callicott
- Campbell
- Caputo
- Carlson
- Carnap
- Carnap
- Carnap
- Carnap
- Carnap
- Carnap
- Carnap
- Carnap
- Carnap
- Carnap
- Carnap
- Carnap
- Carr
- Carr
- Carroll
- Carroll
- Carroll
- Carroll
- Carroll
- Cartwright
- Carus
- Cavell
- Cavell
- Cavell
- Cavell
- Cavell
- Cerbone
- Chakrabarti
- Chakrabarti
- Chakrabarti
- Chakrabarti
- Chalmers
- Chalmers
- Chalmers
- Chalmers
- Chalmers
- Chalmers
- Chalmers
- Chastain
- Chatterjee
- Chenyang
- Chomsky
- Chomsky
- Chomsky
- Chomsky
- Chomsky
- Chomsky
- Chomsky
- Chomsky
- Chomsky
- Chomsky
- Chomsky
- Chomsky
- Chrisley
- Chrisley
- Church
- Churchland
- Churchland
- Churchland
- Churchland
- Churchland
- Clark
- Clark
- Clark
- Clark
- Clarke
- Cleveland
- Cobb
- Cohen
- Cohen
- Cohen
- Collingwood
- Collingwood
- Collingwood
- Collingwood
- Collins
- Collins
- Collins
- Conant
- Connolly
- Conze
- Cooper
- Cooper
- Cooper
- Copleston
- Correia
- Correia
- Correia
- Cowherds
- Cowherds
- Cowie
- Craik
- Crary
- Crisp
- Cronin
- Cronon
- Crowe
- Cua
- Currie
- Dahlstrom
- Dancy
- Dancy
- Danto
- Danto
- Danto
- Danto
- Danto
- Danto
- Darwall
- Darwin
- Dasgupta
- Dasgupta
- Dasti
- Davidson
- Davidson
- Davidson
- Davidson
- Davidson
- Davies
- Davies
- Davies
- Davies
- Davis
- Davis
- Dawkins
- de Bary
- de Bary
- De Caro
- De Caro
- de Waal
- de Waal
- Dearden
- Deleuze
- Deleuze
- Deleuze
- Denis
- Denis
- Dennett
- Dennett
- Dennett
- Dennett
- Dennett
- Dennett
- Dennett
- Dennett
- Dennett
- Depoortere
- DeRose
- deRosset
- Derrida
- Derrida
- Derrida
- Derrida
- Derrida
- Derrida
- Derrida
- Derrida
- Devall
- Devall
- DeVries
- Dewey
- Dewey
- Dewey
- Dewey
- Dewey
- Dewey
- Dewey
- Di Cesare
- Diamond
- Dickie
- Dickie
- Dilthey
- Diprose
- Dobzhansky
- Donagan
- Donovan
- Downs
- Draper
- Dravid
- Dray
- Dray
- Dray
- Dreben
- Dretske
- Dretske
- Dretske
- Dretske
- Dretske
- Dreyfus
- Dreyfus
- Dreyfus
- Dreyfus
- Dreyfus
- Dreyfus
- Dreyfus
- Dreyfus
- Dreyfus
- Driver
- Driver
- Ducasse
- Duhem
- Dummett
- Dummett
- Dummett
- Duncan
- Dupré
- Durbin
- Dutihl Novaes
- Dutton
- D’Agostino
- D’Amato
- Earman
- Earman
- Earman
- Ebbs
- Eddington
- Eliot
- Ellis
- Emerson
- Engstrom
- Eribon
- Evans
- Evernden
- Fackenheim
- Fackenheim
- Fairbairn
- Falk
- Farrell
- Faye
- Feagin
- Feenberg
- Feenberg
- Feenberg
- Feferman
- Feigl
- Fendler
- Fendler
- Ferrara
- Feyerabend
- Figal
- Fine
- Fine
- Fine
- Finlayson
- Firth
- Firth
- Flew
- Flew
- Floridi
- Fodor
- Fodor
- Fodor
- Fodor
- Fodor
- Foot
- Forst
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Foucault
- Fox
- Fox
- Frankena
- Frankfurt
- Franks
- Franks
- Franks
- Fraser
- Freddoso
- Freeland
- Freeland
- Freeland
- Freeman
- Frege
- Frege
- Freire
- Freire
- Freud
- Friedan
- Friedlander
- Friedman
- Friedman
- Friedman
- Friedman
- Friis
- Frost-Arnold
- Fung
- Fung
- Føllesdal
- Føllesdal
- Gadamer
- Gadamer
- Gadamer
- Gadamer
- Gadamer
- Gadamer
- Gadamer
- Gadamer
- Gadamer
- Gadamer
- Galison
- Gallie
- Gandy
- Ganeri
- Ganeri
- Garber
- Garber
- Gardiner
- Gardiner
- Gardiner
- Gardner
- Garfield
- Garrison
- Gascoigne
- Gatens
- Gaus
- Gaus
- Gaus
- Gaut
- Gaut
- George
- George
- George
- Gilligan
- Gillon
- Giunti
- Glendinning
- Glymour
- Glymour
- Godfrey-Smith
- Godlovitch
- Goehr
- Goldblatt
- Goldman
- Goldman
- Goldman
- Golomb
- Goodman
- Goodman
- Gordon
- Gordon
- Gore
- Goto-Jones
- Gould
- Gould
- Gracia
- Gracia
- Gracyk
- Gracyk
- Graham
- Graham
- Gray
- Greco
- Greco
- Green
- Gregor
- Gregory
- Grene
- Grene
- Grene
- Grice
- Grice
- Griffiths
- Griffiths
- Grondin
- Grondin
- Grondin
- Grondin
- Grosz
- Gruen
- Grünbaum
- Guarino
- Guay
- Guignon
- Guignon
- Gupta
- Guyer
- Guyer
- Guyer
- Gödel
- Gödel
- Habermas
- Habermas
- Habermas
- Habermas
- Habermas
- Habermas
- Habermas
- Habermas
- Habermas
- Habermas
- Habermas
- Habermas
- Hacker
- Hacking
- Hacking
- Hacking
- Hagberg
- Hallward
- Hamilton
- Hamilton
- Hamlyn
- Hampshire
- Hanke
- Hansen
- Hansen
- Hanson
- Haraway
- Hare
- Hare
- Harman
- Harman
- Harman
- Harman
- Harman
- Harrington
- Harris
- Harrison
- Hasker
- Hatab
- Haugeland
- Haugeland
- Haugeland
- Hawking
- Hawthorne
- Hawthorne
- Hawthorne
- Heal
- Hegel
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Heidegger
- Hein
- Heisig
- Heisig
- Held
- Hellie
- Hellie
- Hellie
- Hellie
- Hempel
- Hempel
- Hempel
- Hempel
- Herman
- Herman
- Hershock
- Hershock
- Hershowitz
- Hesse
- Hesse
- Hesse
- Heyting
- Hick
- Hick
- Hick
- Hickman
- Higgins
- Hill
- Hill
- Hill
- Hintikka
- Hirsch
- Hirst
- Hirst
- Hockett
- Hoerl
- Hofweber
- Honig
- Honneth
- Honneth
- Honneth
- Honneth
- Hook
- Hooker
- hooks
- hooks
- Hookway
- Hopkins
- Horgan
- Horkheimer
- Horkheimer
- Horkheimer
- Horkheimer
- Hornsby
- Horwich
- Howard-Snyder
- Howard-Snyder
- Howson
- Hrdy
- Hu
- Hubbard
- Hull
- Hume
- Hunter
- Hursthouse
- Hursthouse
- Hursthouse
- Husserl
- Husserl
- Hylton
- Hylton
- Höffe
- Ihde
- Ihde
- Ihde
- Ihde
- Ihde
- Ihde
- Ihde
- Ihde
- Ingarden
- Irigaray
- Irigaray
- Irigaray
- Iseminger
- Ivanhoe
- Izutsu
- Izutsu
- Jackson
- Jackson
- Jackson
- James
- Jammer
- Javier-Castellanos
- Jaynes
- Jeffrey
- Jesperson
- Jesperson
- Jesperson
- Jonas
- Jonas
- Jones
- Joos
- Jost
- Juhl
- Kagan
- Kajiyama
- Kamm
- Kamm
- Kamp
- Kane
- Kant
- Kant
- Kant
- Kaplan
- Kasulis
- Kasulis
- Katz
- Katz
- Katz
- Katz
- Katz
- Kaufmann
- Kaufmann
- Kazepides
- Keane
- Kearney
- Keiji
- Keiji
- Keller
- Kelly
- Kelly
- Kenny
- Kenny
- Khoo
- Kieran
- Kieran
- Kierkegaard
- Kierkegaard
- Kim
- Kim
- King
- Kirk
- Kirloskar-Steinbach
- Kitarō
- Kitarō
- Kitarō
- Kitarō
- Kitcher
- Kitcher
- Kivy
- Kivy
- Kivy
- Kivy
- Klosko
- Kluge
- Knobe
- Knowles
- Kohlberg
- Koopman
- Kopf
- Korsmeyer
- Koselleck
- Koslicki
- Kraft
- Krasser
- Krausz
- Kraut
- Krell
- Kripke
- Kripke
- Kripke
- Kripke
- Kruks
- Krummel
- Krämer
- Kuhn
- Kuhn
- Kukla
- Kuklick
- Kuusela
- Kymlicka
- Köhnke
- Lacan
- LaFleur
- Lalander
- Lamarque
- Lamarque
- Lamarque
- Lamarque
- Lance
- Lange
- Langer
- Langer
- Lao
- Lasch
- Latour
- Laudan
- Laudan
- Laudan
- Lebens
- Leddy
- Lee
- Leftow
- Lehnert
- Leiter
- Leopold
- Lepore
- Levi
- Levi
- Levin
- Levinas
- Levinas
- Levinas
- Levinas
- Levinas
- Levine
- Levins
- Levinson
- Levinson
- Levy
- Lewis
- Lewis
- Lewis
- Lewis
- Lewis
- Lewis
- Lewis
- Lewis
- Lewis
- Lewis
- Lewis
- Light
- Lipstadt
- Lister
- Livengood
- Livingston
- Lloyd
- Lloyd
- Longino
- Lopes
- Lopes
- Louden
- Louis
- Lowe
- Loy
- Loy
- Luntley
- Luper-Foy
- Lusthaus
- Lycan
- Lycan
- Lyotard
- Lyotard
- Macarthur
- MacDowell
- MacIntyre
- MacIntyre
- Mackie
- Mackie
- Mackie
- Mackie
- Maes
- Maffie
- Maher
- Makeham
- Makkreel
- Malcolm
- Malcolm
- Malpas
- Marcano
- Marcel
- Marcel
- Marcel
- Marcel
- Marcus
- Marcuse
- Marcuse
- Marcuse
- Marcuse
- Marcuse
- Margolis
- Margolis
- Margolis
- Margolis
- Marquit
- Marr
- Marra
- Marra
- Marshall
- Marshall
- Marshall
- Martin
- Maruyama
- Maruyama
- Maruyama
- Marx
- Masao
- Masschelein
- Matilal
- Matilal
- Matilal
- Matilal
- Matilal
- Matravers
- Mayeda
- Maynard Smith
- McAleer
- McCarthy
- McCarthy
- McCormick
- McCullough
- McCumber
- McDowell
- McDowell
- McDowell
- McGinn
- McKibben
- McLaren
- McLaren
- Medina
- Meggle
- Melden
- Mele
- Mendieta
- Menzies
- Merchant
- Merleau-Ponty
- Merleau-Ponty
- Merleau-Ponty
- Metz
- Mies
- Mill
- Mill
- Miller
- Miller
- Millikan
- Millikan
- Millikan
- Mills
- Mills
- Minar
- Mink
- Mink
- Minsky
- Minsky
- Minsky
- Minsky
- Minsky
- Minteer
- Misak
- Mitcham
- Mitchell
- Moltmann
- Montague
- Moore
- Moore
- Moore
- Moore
- Moore
- Moran
- Morris
- Morris
- Morris
- Motherwell
- Mou
- Mouffe
- Mouffe
- Mulhall
- Mulhall
- Mulhall
- Muller
- Mumford
- Mumford
- Mumford
- Murphy
- Murphy
- Nadler
- Nagel
- Nagel
- Nancy
- Nehamas
- Neurath
- Newell
- Newell
- Newton
- Nidditch
- Nietzsche
- Nietzsche
- Nietzsche
- Nietzsche
- Nietzsche
- Nietzsche
- Noddings
- Noddings
- Nolan
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- Zahavi
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- Zahavi
- Zangwill
- Zea
- Zhang
- Žižek
- Publication venue
- 'Cambridge University Press (CUP)'
- Publication date
- 01/01/2019
- Field of study
The philosophical study of human action begins with Plato and Aristotle. Their influence in late antiquity and the Middle Ages yielded sophisticated theories of action and motivation, notably in the works of Augustine and Aquinas.1 But the ideas that were dominant in 1945 have their roots in the early modern period, when advances in physics and mathematics reshaped philosophy
Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial
- Author
- Abano Nenette
- Abbdul-saheb Mudhar
- Adedoyin Temi
- Adell Victoria
- Adesina Tolu
- Adie Katja
- Adil-Smith Jennifer
- Ahmad Nasar
- Ahmed Ashraf
- Ahmed Iman
- Al-Mayhani Talal
- Al-Shahi Salman Rustam
- Alam Mohammad Irfan
- Albazzaz Mo
- Ali Ali
- Alipio Francis
- Allen Christopher
- Allison Joanna
- Amey Isobel
- Amis Elaine
- Amlani Sageet
- Amoils Shannon
- Amor Kelly
- Anderson Rosemary
- Andole Sreeman
- Anjum Talat
- Ankolekar Sandeep
- Annamalai Arunkumar
- Anthony Alpha
- Anversha Ajmal
- Anwar Ijaz
- Anwar Sajjad
- Appleton Jason
- Argandona Lucia
- Armitage Jane
- Ashton Amy
- Atkinson Natalie
- Auld Grace
- Avis Joanne
- Aweid Basaam
- Ayres Georgina
- Azhar Khalid
- Bagnall Caroline
- Baig Farrukh
- Baigent Colin
- Bailey Duncan
- Baird Yolanda
- Bakawala Rehana
- Baker John
- Baker Pauline
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- Bhaskaran Biju
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- Ramachandran Sankaranarayana
- Ramadan Hawraman
- Ramshaw Alex
- Rana Pratap
- Randall Marc
- Rashed Khalid
- Rashmi Sindhu
- Ravenhill Garth
- Rayessa Rayessa
- Reckless Ian
- Reddan Julie
- Reddan Julie
- Redgrave Jessica
- Redjep Ozlem
- Remegoso Alda
- Richard Bella
- Richards Emma
- Rinkel Gabriel
- Roberts Josh
- Robinson Matthew
- Robinson Naomi
- Rodgers Alicia
- Rodriguez Aryelly
- Roffe Christine
- Roffe Jack
- Roganova Tatjana
- Rogers Emily
- Rogers Gill
- Rojas Javier
- Ross Sarah
- Roughan Caroline
- Rudd Tony
- Rudenko Hannah
- Saada Janak
- Saastamoinen Kari
- Sajid Mahmud
- Sakka Eleni
- Salehin Maqsud
- Salek-Haddadi Afraim
- Salih Isam
- Sally Moore
- Sandercock PAG
- Sangombe Mirriam
- Sangster Graeme
- Sanyal Ranjan
- Sarah Procter
- Sarah Procter
- Sattar Naweed
- Sattar Saira
- Saulat Afaq
- Saulat Afaq
- Schofield Christine
- Schulz Ursula
- Schumacher Natasha
- Schwarz Stefan
- Seagrave Samantha
- Sekaran Lakshmanan
- Sesay Juliana
- Sethuraman Sakthivel
- Shackcloth Daniela
- Shah Alex
- Shah Sweni
- Shahmehri Shahrzad
- Sharma Nikhil
- Sharpe Simon
- Shaw Kelly Marie
- Shaw Louise
- Sheikh Saima
- Shekhar Raj
- Shelton Faye
- Shinh Naval
- Shread Ian
- Shukla Avani
- Siddegowda Prasad
- Siddiq Muhammad
- Siddiqui Amber
- Siddiqui Anwer
- Sigsworth Andrew
- Simon Rohan
- Sims Don
- Singh Arun
- Sinha Devesh
- Skinner Helen
- Slade Peter
- Smart Amanda
- Smith Andrew
- Smith Fiona
- Smith Gemma Marie
- Smith Simon
- Smith Wilma
- Smyth Nigel
- Spencer Jayne
- Sprigg N
- Srinivasan Meena
- Stafford Samantha
- Stafford Samantha
- Stanners Andrew
- Steele Amy
- Stephen J
- Stephens Claire
- Stevens Angela
- Stevens Stephanie
- Stevenson Sarah
- Stewart Kelvin
- Stocks Kathy
- Stone Andrew
- Storton Sharon
- Strain David
- Subramonian Santhosh
- Sudlow CLM
- Sukdeo Varthi
- Sullivan Frank
- Sultan Sulaiman
- Suttling Anne
- Sutton Claire
- Sutton Patrick
- Sutton Victoria
- Sword Jane
- Sykes Lucy
- Symonds Stuart
- Szabo Susan
- Tallantyre Emma
- Tanate Alfonso
- Tandy Jane
- Tate Margaret
- Tauro Suzanne
- Tayler Michelle
- Taylor Pat
- Taylor Vicky
- Teal Rachel
- Temple Natalie
- Thant Hlaing
- Thavanesan Kamy
- Thomas Isobel
- Thomas Kelly
- Thomas Philip
- Thomas Sarah
- Thompson Philip
- Thompson Susan
- Thompson Teresa
- Thompson-Jones Helen
- Thomson Audrey
- Thornthwaite Sarah
- Thorpe Kevin
- Tilley Victoria
- Tiwari Divya
- Tomlin Dawn
- Tomlinson Benjamin
- Treadwell Shelley
- Tribbeck Michele
- Trippier Sarah
- Triscott Claire
- Triscott Claire
- Tryambake Dinesh
- Tucker Laura
- Tucker Susan
- Turfrey Jennifer
- Tysoe Sharon
- Ullah Khalil
- Valentine Stacey
- van Someren Chloe
- Varquez Resti
- Vasileiadis Evangelos
- Vassallo Joseph
- Venter Marius
- Veraque Emelda
- Verrion Anna
- Vettimootal Johnson Venetia
- Vickers Carinna
- Walford Jamie
- Walker Allan
- Walker Marion
- Walker Pauli
- Walker Susannah
- Wallace Aine
- Wallace Rebecca
- Wallace Rebecca
- Walstow Deborah
- Walter Deborah
- Walters Ashleigh
- Wani Mushtaq
- Ward Deborah
- Wardlaw JM
- Watchurst Caroline
- Waterfield Kelly
- Waterfield Kelly
- Watson Fran
- Waugh Dean
- Webb Tom
- Webber Adam
- Webster Timothy
- Weinling Marie
- Weir Nic
- Weir Pauline
- Welch Angela
- Werring DJ
- Whitcher Alison
- White James
- White Julie
- White PM
- White Susan
- Whiteley WN
- Whiteman Jessica
- Whiteman Jessica
- Whiting Robert
- Whittamore Katherine
- Wiggam Ivan
- Wilding Peter
- Wilkes Gwendoline
- Wilkinson Mark
- Willberry Angela
- Williams Carol
- Williams Rebecca
- Williams-Yesson Barbara
- Willmot Mark
- Wilson David
- Wilson Duncan
- Wilson Jenny
- Wilson Lisa
- Wilson Sarah
- Wiltshire Alison
- Wood Diane
- Wood Edith
- Wood Lisa
- Woodward Stephen
- Wright Fiona
- Wroath Belinda
- Wynter Inez
- Yadava Rajendra
- Yip Brigitte
- Young Andrew
- Zachariah George
- Zahoor Tajammal
- Zoe Mellor
- Publication venue
- 'Elsevier BV'
- Publication date
- 29/06/2019
- Field of study
Background:
Antiplatelet therapy reduces the risk of major vascular events for people with occlusive vascular disease, although it might increase the risk of intracranial haemorrhage. Patients surviving the commonest subtype of intracranial haemorrhage, intracerebral haemorrhage, are at risk of both haemorrhagic and occlusive vascular events, but whether antiplatelet therapy can be used safely is unclear. We aimed to estimate the relative and absolute effects of antiplatelet therapy on recurrent intracerebral haemorrhage and whether this risk might exceed any reduction of occlusive vascular events.
Methods:
The REstart or STop Antithrombotics Randomised Trial (RESTART) was a prospective, randomised, open-label, blinded endpoint, parallel-group trial at 122 hospitals in the UK. We recruited adults (≥18 years) who were taking antithrombotic (antiplatelet or anticoagulant) therapy for the prevention of occlusive vascular disease when they developed intracerebral haemorrhage, discontinued antithrombotic therapy, and survived for 24 h. Computerised randomisation incorporating minimisation allocated participants (1:1) to start or avoid antiplatelet therapy. We followed participants for the primary outcome (recurrent symptomatic intracerebral haemorrhage) for up to 5 years. We analysed data from all randomised participants using Cox proportional hazards regression, adjusted for minimisation covariates. This trial is registered with ISRCTN (number ISRCTN71907627).
Findings:
Between May 22, 2013, and May 31, 2018, 537 participants were recruited a median of 76 days (IQR 29–146) after intracerebral haemorrhage onset: 268 were assigned to start and 269 (one withdrew) to avoid antiplatelet therapy. Participants were followed for a median of 2·0 years (IQR [1·0– 3·0]; completeness 99·3%). 12 (4%) of 268 participants allocated to antiplatelet therapy had recurrence of intracerebral haemorrhage compared with 23 (9%) of 268 participants allocated to avoid antiplatelet therapy (adjusted hazard ratio 0·51 [95% CI 0·25–1·03]; p=0·060). 18 (7%) participants allocated to antiplatelet therapy experienced major haemorrhagic events compared with 25 (9%) participants allocated to avoid antiplatelet therapy (0·71 [0·39–1·30]; p=0·27), and 39 [15%] participants allocated to antiplatelet therapy had major occlusive vascular events compared with 38 [14%] allocated to avoid antiplatelet therapy (1·02 [0·65–1·60]; p=0·92).
Interpretation:
These results exclude all but a very modest increase in the risk of recurrent intracerebral haemorrhage with antiplatelet therapy for patients on antithrombotic therapy for the prevention of occlusive vascular disease when they developed intracerebral haemorrhage. The risk of recurrent intracerebral haemorrhage is probably too small to exceed the established benefits of antiplatelet therapy for secondary prevention
Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial
- Author
- Abano Nenette
- Abbdul-saheb Mudhar
- Adedoyin Temi
- Adell Victoria
- Adesina Tolu
- Adie Katja
- Adil-Smith Jennifer
- Ahmad Nasar
- Ahmed Ashraf
- Ahmed Iman
- Al-Mayhani Talal
- Al-Shahi Salman Rustam
- Alam Mohammad Irfan
- Albazzaz Mo
- Ali Ali
- Alipio Francis
- Allen Christopher
- Allison Joanna
- Amey Isobel
- Amis Elaine
- Amlani Sageet
- Amoils Shannon
- Amor Kelly
- Anderson Rosemary
- Andole Sreeman
- Anjum Talat
- Ankolekar Sandeep
- Annamalai Arunkumar
- Anthony Alpha
- Anversha Ajmal
- Anwar Ijaz
- Anwar Sajjad
- Appleton Jason
- Argandona Lucia
- Armitage Jane
- Ashton Amy
- Atkinson Natalie
- Auld Grace
- Avis Joanne
- Aweid Basaam
- Ayres Georgina
- Azhar Khalid
- Bagnall Caroline
- Baig Farrukh
- Baigent Colin
- Bailey Duncan
- Baird Yolanda
- Bakawala Rehana
- Baker John
- Baker Pauline
- Balazikova Olga
- Balian Linda
- Baliga Vidya
- Balitska Olesia
- Ball Julie
- Ball Margaret
- Ballantine Robert
- Bamford John
- Banaras Azra
- Barber Mark
- Barbon Emma
- Barker James
- Barr Charlotte
- Barrie Elizabeth
- Barron Luke
- Barry Adrian
- Bateman Gavin
- Bates Michelle
- Bathula Rajaram
- Battersby-Wood Emma
- Bayliss Pauline
- Beadle Hannah
- Bearne Helen
- Beaty Teresa
- Beaves Emily
- Bell Angela
- Bell Jo
- Bell Murdina
- Bellfield Ruth
- Beranova Eva
- Bergin Adrian
- Bhakri Harbens
- Bhalla Ajay
- Bharaj Kiranjit
- Bhargava Maneesh
- Bhaskaran Biju
- Bhatnagar Priya
- Birchall Kathryn
- Birns Jonathan
- Black Toby
- Blades Alex
- Blair Caroline
- Blair Caroline
- Blair Gordon
- Blane Sujata
- Blank Catrin
- Blight Adrian
- Board Joanne
- Board Sarah
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- Chandrakumar Aberami
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- Hedstrom Amanda
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- Kumar Pradeep
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- Landers Geraldine
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- Lerpiniere Christine
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- Littleton Edward
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- Longland Barbara
- Lopez Paula
- Lovelock Caroline
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- Lucas Suzanne
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- MacInnes Brian
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- MacLeod Mary
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- Maddula Mohana
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- Rashed Khalid
- Rashmi Sindhu
- Ravenhill Garth
- Rayessa Rayessa
- Reckless Ian
- Reddan Julie
- Reddan Julie
- Redgrave Jessica
- Redjep Ozlem
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- Richards Emma
- Rinkel Gabriel
- Roberts Josh
- Robinson Matthew
- Robinson Naomi
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- Rodriguez Aryelly
- Roffe Christine
- Roffe Jack
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- Rogers Emily
- Rogers Gill
- Rojas Javier
- Ross Sarah
- Roughan Caroline
- Rudd Tony
- Rudenko Hannah
- Saada Janak
- Saastamoinen Kari
- Sajid Mahmud
- Sakka Eleni
- Salehin Maqsud
- Salek-Haddadi Afraim
- Salih Isam
- Sally Moore
- Sandercock PAG
- Sangombe Mirriam
- Sangster Graeme
- Sanyal Ranjan
- Sarah Procter
- Sarah Procter
- Sattar Naweed
- Sattar Saira
- Saulat Afaq
- Saulat Afaq
- Schofield Christine
- Schulz Ursula
- Schumacher Natasha
- Schwarz Stefan
- Seagrave Samantha
- Sekaran Lakshmanan
- Sesay Juliana
- Sethuraman Sakthivel
- Shackcloth Daniela
- Shah Alex
- Shah Sweni
- Shahmehri Shahrzad
- Sharma Nikhil
- Sharpe Simon
- Shaw Kelly Marie
- Shaw Louise
- Sheikh Saima
- Shekhar Raj
- Shelton Faye
- Shinh Naval
- Shread Ian
- Shukla Avani
- Siddegowda Prasad
- Siddiq Muhammad
- Siddiqui Amber
- Siddiqui Anwer
- Sigsworth Andrew
- Simon Rohan
- Sims Don
- Singh Arun
- Sinha Devesh
- Skinner Helen
- Slade Peter
- Smart Amanda
- Smith Andrew
- Smith Fiona
- Smith Gemma Marie
- Smith Simon
- Smith Wilma
- Smyth Nigel
- Spencer Jayne
- Sprigg N
- Srinivasan Meena
- Stafford Samantha
- Stafford Samantha
- Stanners Andrew
- Steele Amy
- Stephen J
- Stephens Claire
- Stevens Angela
- Stevens Stephanie
- Stevenson Sarah
- Stewart Kelvin
- Stocks Kathy
- Stone Andrew
- Storton Sharon
- Strain David
- Subramonian Santhosh
- Sudlow CLM
- Sukdeo Varthi
- Sullivan Frank
- Sultan Sulaiman
- Suttling Anne
- Sutton Claire
- Sutton Patrick
- Sutton Victoria
- Sword Jane
- Sykes Lucy
- Symonds Stuart
- Szabo Susan
- Tallantyre Emma
- Tanate Alfonso
- Tandy Jane
- Tate Margaret
- Tauro Suzanne
- Tayler Michelle
- Taylor Pat
- Taylor Vicky
- Teal Rachel
- Temple Natalie
- Thant Hlaing
- Thavanesan Kamy
- Thomas Isobel
- Thomas Kelly
- Thomas Philip
- Thomas Sarah
- Thompson Philip
- Thompson Susan
- Thompson Teresa
- Thompson-Jones Helen
- Thomson Audrey
- Thornthwaite Sarah
- Thorpe Kevin
- Tilley Victoria
- Tiwari Divya
- Tomlin Dawn
- Tomlinson Benjamin
- Treadwell Shelley
- Tribbeck Michele
- Trippier Sarah
- Triscott Claire
- Triscott Claire
- Tryambake Dinesh
- Tucker Laura
- Tucker Susan
- Turfrey Jennifer
- Tysoe Sharon
- Ullah Khalil
- Valentine Stacey
- van Someren Chloe
- Varquez Resti
- Vasileiadis Evangelos
- Vassallo Joseph
- Venter Marius
- Veraque Emelda
- Verrion Anna
- Vettimootal Johnson Venetia
- Vickers Carinna
- Walford Jamie
- Walker Allan
- Walker Marion
- Walker Pauli
- Walker Susannah
- Wallace Aine
- Wallace Rebecca
- Wallace Rebecca
- Walstow Deborah
- Walter Deborah
- Walters Ashleigh
- Wani Mushtaq
- Ward Deborah
- Wardlaw JM
- Watchurst Caroline
- Waterfield Kelly
- Waterfield Kelly
- Watson Fran
- Waugh Dean
- Webb Tom
- Webber Adam
- Webster Timothy
- Weinling Marie
- Weir Nic
- Weir Pauline
- Welch Angela
- Werring DJ
- Whitcher Alison
- White James
- White Julie
- White PM
- White Susan
- Whiteley WN
- Whiteman Jessica
- Whiteman Jessica
- Whiting Robert
- Whittamore Katherine
- Wiggam Ivan
- Wilding Peter
- Wilkes Gwendoline
- Wilkinson Mark
- Willberry Angela
- Williams Carol
- Williams Rebecca
- Williams-Yesson Barbara
- Willmot Mark
- Wilson David
- Wilson Duncan
- Wilson Jenny
- Wilson Lisa
- Wilson Sarah
- Wiltshire Alison
- Wood Diane
- Wood Edith
- Wood Lisa
- Woodward Stephen
- Wright Fiona
- Wroath Belinda
- Wynter Inez
- Yadava Rajendra
- Yip Brigitte
- Young Andrew
- Zachariah George
- Zahoor Tajammal
- Zoe Mellor
- Publication venue
- 'Elsevier BV'
- Publication date
- 29/06/2019
- Field of study
Background:
Antiplatelet therapy reduces the risk of major vascular events for people with occlusive vascular disease, although it might increase the risk of intracranial haemorrhage. Patients surviving the commonest subtype of intracranial haemorrhage, intracerebral haemorrhage, are at risk of both haemorrhagic and occlusive vascular events, but whether antiplatelet therapy can be used safely is unclear. We aimed to estimate the relative and absolute effects of antiplatelet therapy on recurrent intracerebral haemorrhage and whether this risk might exceed any reduction of occlusive vascular events.
Methods:
The REstart or STop Antithrombotics Randomised Trial (RESTART) was a prospective, randomised, open-label, blinded endpoint, parallel-group trial at 122 hospitals in the UK. We recruited adults (≥18 years) who were taking antithrombotic (antiplatelet or anticoagulant) therapy for the prevention of occlusive vascular disease when they developed intracerebral haemorrhage, discontinued antithrombotic therapy, and survived for 24 h. Computerised randomisation incorporating minimisation allocated participants (1:1) to start or avoid antiplatelet therapy. We followed participants for the primary outcome (recurrent symptomatic intracerebral haemorrhage) for up to 5 years. We analysed data from all randomised participants using Cox proportional hazards regression, adjusted for minimisation covariates. This trial is registered with ISRCTN (number ISRCTN71907627).
Findings:
Between May 22, 2013, and May 31, 2018, 537 participants were recruited a median of 76 days (IQR 29–146) after intracerebral haemorrhage onset: 268 were assigned to start and 269 (one withdrew) to avoid antiplatelet therapy. Participants were followed for a median of 2·0 years (IQR [1·0– 3·0]; completeness 99·3%). 12 (4%) of 268 participants allocated to antiplatelet therapy had recurrence of intracerebral haemorrhage compared with 23 (9%) of 268 participants allocated to avoid antiplatelet therapy (adjusted hazard ratio 0·51 [95% CI 0·25–1·03]; p=0·060). 18 (7%) participants allocated to antiplatelet therapy experienced major haemorrhagic events compared with 25 (9%) participants allocated to avoid antiplatelet therapy (0·71 [0·39–1·30]; p=0·27), and 39 [15%] participants allocated to antiplatelet therapy had major occlusive vascular events compared with 38 [14%] allocated to avoid antiplatelet therapy (1·02 [0·65–1·60]; p=0·92).
Interpretation:
These results exclude all but a very modest increase in the risk of recurrent intracerebral haemorrhage with antiplatelet therapy for patients on antithrombotic therapy for the prevention of occlusive vascular disease when they developed intracerebral haemorrhage. The risk of recurrent intracerebral haemorrhage is probably too small to exceed the established benefits of antiplatelet therapy for secondary prevention
SARS-CoV-2-specific immune responses and clinical outcomes after COVID-19 vaccination in patients with immune-suppressive disease
- Author
- Abraham Priyanka
- Adele Sandra
- Al-Taei Saly
- Ali Mohammad
- Amirthalingam Gayatri
- Arnott Maxine
- Atta Maria
- Avenoso Daniele
- Barnes Eleanor
- Basheer Faisal
- Basu Neil
- Beesley Richard
- Bennett Louise
- Bhandal Khushpreet
- Bibi Sagida
- Billingham Lucinda
- Bowden Sarah J.
- Brock James
- Brown Anthony
- Brown Kevin
- Carroll Miles
- Carroll Miles
- Chackathayil Julie
- Chalk Jem
- Churchill Vicky
- Clarke Candice
- Conlon Chris
- Cook Gordon
- Crawley Charles
- Deeks Alexandra
- Dimitriadis Stavros
- Dobson Sue L.
- Dold Chris
- Dunachie Susanna J.
- Duncan Christopher J. A.
- Faria Patricia
- Faustini Sian
- Filer Andrew
- Foulkes Sarah
- Frater John
- Frending Lisa
- Gardiner Siobhan
- Gaskell Charlotte
- Gilmour Ashley
- Gleeson Sarah
- Goodyear Carl S.
- Hahn Gareth
- Hall Victoria
- Hanke Daniel
- Hanke Josef
- Hansford Sam
- Harrison Molly
- Healy Saoirse
- Hopkins Susan
- Hughes Ana
- Hull Diana
- Hurst Erin
- Hutchison Clare
- I de Silva Thushan
- Insch Elspeth
- Ireland Georgina
- Irwin Sophie
- Islam Jasmin
- Jamsen Anni
- Jeffery Katie
- Kearns Pamela
- Keillor Victora
- Kelleher Peter
- Kesavan Murali
- King Andrew
- Kirkham Amanda
- Klenerman Paul
- Koh Mickey B. C.
- Kronsteiner Barbara
- Laidlaw Stephen
- Lambe Teresa
- Lightstone Liz
- Lim Sean H.
- Lim Zixiang
- Lockey Sophie
- Longet Stephanie
- Longet Stephanie
- Loughton Holly
- Lowe Faye
- MacDonald Eilean
- Magwaro Sophia
- Malladi Ram
- Malone Tom
- Manousou Pinelopi
- Marjot Thomas
- Martin Paul
- McAdoo Stephen
- McInnes Iain B.
- McIntyre Stacey
- Meacham Georgina
- Meardon Naomi
- Melville Andrew
- Melville Lisa
- Mentzer Alex
- Middleton Gary
- Miller Paul
- Miller Samantha
- Moore Celia
- Moore Shona C.
- Mortimer Paige
- Mullish Benjamin
- Murray Sam M.
- Najm Aurelie
- Nguyen Dung
- null null
- null null
- null null
- Orchard Kim
- Otter Ashley
- Paterson Caron
- Payne Rebecca
- Phillips Eloise
- Pirrie Sarah
- Pope Ann
- Prendecki Maria
- Provine Nicholas
- Publicover Amy
- Rea Daniel
- Richardson Deborah
- Richter Alex
- Richter Alex G.
- Rodgers Lewis
- Rongkard Patpong
- Rowland-Jones Sarah L.
- Rundell Suzann
- Rutherford Matthew
- Sanderson Robin
- Sandhar Gurjinder
- Satsangi Jack
- Scouse Katy
- Selby Rachael
- Siebert Stefan
- Skelly Donal
- Smith Emily
- Snowden John A.
- Stafford Lizzie
- Stewart Lynn
- Sunzini Flavia
- Taylor Claire
- Thaventhir James E. D.
- Thomas David
- Thomas Sarah
- Thomson Tina
- Tipton Tom
- Tong Andrew
- Travis Simon
- Trivedi Palak
- Trown Doreen
- Turtle Lance
- Uttenthal Ben
- Walker Victoria
- Willicombe Michelle
- Win Zay
- Woolcock Kieran
- Wootton Daniel G.
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2023
- Field of study
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immune responses and infection outcomes were evaluated in 2,686 patients with varying immune-suppressive disease states after administration of two Coronavirus Disease 2019 (COVID-19) vaccines. Overall, 255 of 2,204 (12%) patients failed to develop anti-spike antibodies, with an additional 600 of 2,204 (27%) patients generating low levels (<380 AU ml−1). Vaccine failure rates were highest in ANCA-associated vasculitis on rituximab (21/29, 72%), hemodialysis on immunosuppressive therapy (6/30, 20%) and solid organ transplant recipients (20/81, 25% and 141/458, 31%). SARS-CoV-2-specific T cell responses were detected in 513 of 580 (88%) patients, with lower T cell magnitude or proportion in hemodialysis, allogeneic hematopoietic stem cell transplantation and liver transplant recipients (versus healthy controls). Humoral responses against Omicron (BA.1) were reduced, although cross-reactive T cell responses were sustained in all participants for whom these data were available. BNT162b2 was associated with higher antibody but lower cellular responses compared to ChAdOx1 nCoV-19 vaccination. We report 474 SARS-CoV-2 infection episodes, including 48 individuals with hospitalization or death from COVID-19. Decreased magnitude of both the serological and the T cell response was associated with severe COVID-19. Overall, we identified clinical phenotypes that may benefit from targeted COVID-19 therapeutic strategies
Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial
- Author
- Aberami Chandrakumar
- Abhijit Mate
- Adam Hague
- Adam Webber
- Adrian Barry
- Adrian Bergin
- Adrian Blight
- Adrian Butler
- Adrian Parry-Jones
- Afaq Saulat
- Afaq Saulat
- Afnan Chaudhry
- Afraim Salek-Haddadi
- Aguilar
- Ahamad Hassan
- Ahmad Maatouk
- Ahmed Osman
- Aidan Hutchison
- Aileen McGrath
- Ailsa Fulton
- Aine Wallace
- Ajay Bhalla
- Ajmal Anversha
- Al-Shahi Salman
- Al-Shahi Salman
- Al-Shahi Salman
- Alda Remegoso
- Alex Blades
- Alex Ramshaw
- Alex Shah
- Alexandra Pitt-Ford
- Alfonso Tanate
- Ali Ali
- Ali James
- Alicia Rodgers
- Alison McLoughlin
- Alison Whitcher
- Alison Wiltshire
- Allan MacRaild
- Allan Walker
- Alpha Anthony
- Amanda Buck
- Amanda Hedstrom
- Amanda Hedstrom
- Amanda Smart
- Amber Siddiqui
- Amit Mistri
- Amy Ashton
- Amy Steele
- Anand Nair
- Andrea Hall
- Andrea Ingham
- Andrew Moores
- Andrew Sigsworth
- Andrew Smith
- Andrew Stanners
- Andrew Stone
- Andrew Young
- Anette David
- Angela Bell
- Angela Bowring
- Angela Chamberlain
- Angela Cook
- Angela Dodd
- Angela Stevens
- Angela Welch
- Angela Willberry
- Anita Goff
- Anja Ljubez
- Ann Deary
- Ann Needle
- Anna Verrion
- Anne Hardwick
- Anne Hayes
- Anne Nicolson
- Anne Oshodi
- Anne Suttling
- Annemarie Hunter
- Anoja Rajapakse
- Anthea Parry
- Anthony Byrne
- Anthony Hemsley
- Antony Kenton
- Anu Joyson
- Anwer Siddiqui
- Aparna Pusalkar
- Aravind Manoj
- Arindam Kar
- Arshad Majis
- Arshi Iqbal
- Arumugam Nallasivan
- Arun Singh
- Arunkumar Annamalai
- Aryelly Rodriguez
- Ashish Macaden
- Ashleigh Walters
- Ashraf Ahmed
- Ashraf Nasim
- Audrey Thomson
- Avani Shukla
- Azlisham Mohd Nor
- Azra Banaras
- Baigent
- Balakrishna Kumar
- Baljinder Rai
- Baljit Jagpal
- Bander Dallol
- Barbara Longland
- Barbara Madigan
- Barbara Williams-Yesson
- Barry Moynihan
- Basaam Aweid
- Becky Jupp
- Bejot
- Belinda Wroath
- Bella Richard
- Benjamin Hunt
- Benjamin Hyams
- Benjamin Jackson
- Benjamin Jelley
- Benjamin Tomlinson
- Bernard Esisi
- Bernard Esisi
- Beth Hazel
- Bethan Charles
- Bethan Morse
- Betty Mokoena
- Bev Maund
- Beverley McClelland
- Beverly MacLennan
- Bharath Kumar Cheripelli
- Bhavini Patel
- Biffi
- Biju Bhaskaran
- Bindu Gregory
- Bithi Rahman
- Breffni Keegan
- Brian Clarke
- Brian MacInnes
- Brigid Hairsine
- Brigitte Yip
- Bruno
- Carinna Vickers
- Carla Jordan
- Carmen Constantin
- Carol Denniss
- Carol Graham
- Carol Jeffs
- Carol Williams
- Carole Green
- Carole Hays
- Caroline Bagnall
- Caroline Blair
- Caroline Blair
- Caroline Clarke
- Caroline Clay
- Caroline Crosbie
- Caroline Davies
- Caroline Hogan
- Caroline Lambert
- Caroline Lovelock
- Caroline McGhee
- Caroline Roughan
- Caroline Watchurst
- Cassilda Peixoto
- Catherine Ovington
- Catherine Plewa
- Cathy Mason
- Catrin Blank
- Chakravarthi Rajkumar
- Champa Patel
- Chantel Cox
- Charde Naylor
- Charlotte Barr
- Charlotte Culmsee
- Charlotte Eglinton
- Charlotte Eglinton
- Charlotte Fox
- Charlotte Perkins
- Chelsea Causley
- Cherish Boxall
- Chloe Cox
- Chloe Hughes
- Chloe van Someren
- Chong
- Chris Patterson
- Christian Hansen
- Christina Dickinson
- Christine Dickson
- Christine Kamara
- Christine Kelly
- Christine Lerpiniere
- Christine Lerpiniere
- Christine McAlpine
- Christine Roffe
- Christine Schofield
- Christopher Allen
- Christopher Matthews
- Chukwuka Orefo
- Claire Brown
- Claire Copeland
- Claire Cullen
- Claire Hughes
- Claire James
- Claire Nott
- Claire Nott
- Claire Stephens
- Claire Sutton
- Claire Triscott
- Claire Triscott
- Clare Buckley
- Clare Doyle
- Clare Holmes
- Clark
- CLM Sudlow
- Colin Baigent
- Colin Jenkins
- Connor McGill
- Corinne Pawley
- Counsell
- Damian McArdle
- Daniel Epstein
- Daniel Lasserson
- Daniela Shackcloth
- Danielle Gilmour
- David Broughton
- David Bruce
- David Buchanan
- David Cohen
- David Eveson
- David Jarrett
- David Mangion
- David Minks
- David Ngo
- David Perry
- David Strain
- David Wilson
- Dawn Tomlin
- DE Newby
- Dean Waugh
- Debbie Morgan
- Deborah Howcroft
- Deborah Walstow
- Deborah Walter
- Deborah Ward
- Debs Kelly
- Deepa Jose
- Denise Button
- Denise Donaldson
- Denise Mead
- Dennis
- Derek Esson
- Derek Esson
- Devesh Sinha
- Dheeraj Kalladka
- Diane Gulliver
- Diane Havard
- Diane Wood
- Dinesh Chadha
- Dinesh Tryambake
- Ding
- Dionne Hove
- Dipankar Dutta
- Dipayan Mitra
- Divya Tiwari
- DJ Werring
- Dominic Handley
- Don Sims
- Donna Butler
- Donna Doyle
- Duke Phiri
- Duncan Bailey
- Duncan Wilson
- Ed Gamble
- Edith Wood
- Edward Littleton
- Elaine Amis
- Eleni Sakka
- Elio Giallombardo
- Eliza Foster
- Elizabeth Barrie
- Elizabeth Keeling
- Ellen Brown
- Ellie Gilham
- Elodie Murali
- Eluzai Hakim
- Emelda Veraque
- Emily Beaves
- Emily Dodd
- Emily Osborne
- Emily Rogers
- Emma Barbon
- Emma Battersby-Wood
- Emma Clarkson
- Emma Elliott
- Emma Jinks
- Emma Richards
- Emma Tallantyre
- Emmanuelle Owoyele
- Enda Kerr
- Enoch Orugun
- Eoin O'Brien
- Esther Erumere
- Eva Beranova
- Evangelos Vasileiadis
- Evelyne Burssens
- Faith Kibutu
- Farrukh Baig
- Farzana Patel
- Faye Shelton
- Fenglin Guo
- Ferghal McVerry
- Fergus Doubal
- Fiona Brodie
- Fiona Davis
- Fiona Humphries
- Fiona Moreton
- Fiona Price
- Fiona Smith
- Fiona Wright
- Flynn
- Fran Watson
- Frances Harrington
- Frances Hurford
- Frances Justin
- Francis Alipio
- Frank Sullivan
- Gabriel Rinkel
- Gabriella Howard
- Gail Hann
- Garcia-Yebenes
- Garth Ravenhill
- Gary Ford
- Gavin Bateman
- GD Murray
- Gemma Grimwood
- Gemma Marie Smith
- George Bunea
- George Ghaly
- George Harston
- George Zachariah
- Georgina Ayres
- Geraldine Landers
- Gill Rogers
- Gillian Cluckie
- Gillian Courtauld
- Gillian Kerr
- Gillian Mead
- Girish Muddegowda
- Giulia Lenti
- Glyn Fletcher
- Glyn Gainard
- Gokhale
- Gonzalez-Perez
- Gordon Blair
- Gordon Lowe
- Grace Auld
- Graeme Sangster
- Gwendoline Wilkes
- Hannah Beadle
- Hannah Crowther
- Hannah Rudenko
- Harald Proeschel
- Harbens Bhakri
- Hardi Hassan
- Hart
- Hawraman Ramadan
- Hayley Bridger
- Hayley Denic
- Hayley Kingwell
- Heather Gow
- Hedley Emsley
- Heidi Lawson
- Helen Bearne
- Helen Brew
- Helen Cochrane
- Helen Durman
- Helen Guy
- Helen Hayhoe
- Helen Moroney
- Helen Skinner
- Helen Thompson-Jones
- Hemphill
- Henry De Berker
- Hicks
- Hlaing Ni
- Hlaing Thant
- Holly Maguire
- Hróbjartsson
- Ian Reckless
- Ian Shread
- Ifan Jones
- Ifan Jones
- Ijaz Anwar
- Ilse Burger
- Iman Ahmed
- Imogen Gartrell
- Indra Chadbourn
- Indranil Mukherjee
- Inez Wynter
- Ingrid Kane
- Irene Martin
- Isabel Hostettler
- Isabel Huggett
- Isam Salih
- Isobel Amey
- Isobel Thomas
- Ivan Wiggam
- J Stephen
- Jack Perry
- Jack Roffe
- Jacqueline Furnace
- Jacqueline McKee
- Jacqui Leggett
- James Barker
- James Choulerton
- James Cunningham
- James Kennedy
- James McIlmoyle
- James Richard Marigold
- James White
- Jamie Walford
- Janak Saada
- Jane Armitage
- Jane Gaylard
- Jane Gray
- Jane Herman
- Jane Homan
- Jane Perez
- Jane Sword
- Jane Tandy
- Janet Putterill
- Janice Irvine
- Janice O'Connell
- Jason Appleton
- Javed Imam
- Javier Rojas
- Jayne Foot
- Jayne Spencer
- Jean Buxton
- Jeanette Grocott
- Jeb Palmer
- Jennifer Adil-Smith
- Jennifer Elliot
- Jennifer Hurley
- Jennifer Mitchell
- Jennifer Turfrey
- Jenny Jagger
- Jenny Peters
- Jenny Wilson
- Jessica Redgrave
- Jessica Whiteman
- Jessica Whiteman
- Jill Gallagher
- Jill Greig
- Jim Kelly
- JM Wardlaw
- Jo Bell
- Jo Fletcher
- Jo Howe
- Joanna Allison
- Joanna Breeds
- Joanna O'Reilly
- Joanne Avis
- Joanne Board
- Joanne Garfield-Smith
- Joanne Hiden
- Joanne Howard
- Joanne Mcgee
- Jobbin Francis
- Johanna Carrie
- Johannes du Plessis
- John Baker
- John Bamford
- Jon Glass
- Jonathan Birns
- Jonathan Drever
- Jonathan Emberson
- Jonathan Hewitt
- Jordan Ewing
- Jordi Morell
- Joseph Devine
- Joseph Vassallo
- Josette Milligan
- Josh Roberts
- Josin Jose
- Judith Clarke
- Judith Dube
- Juliana Sesay
- Julie Ball
- Julie Cageao
- Julie Cronin
- Julie Meir
- Julie Reddan
- Julie Reddan
- Julie White
- Justin Penge
- Kailash Krishnan
- Kamy Thavanesan
- Karen Crabtree
- Karen Dunne
- Karen Innes
- Kari Saastamoinen
- Karin Gupwell
- Karla Jennings-Preece
- Kashif Musarrat
- Kate Kennedy
- Kath Chapman
- Kath Pasco
- Katherine Marks
- Katherine Whittamore
- Kathleen Horan
- Kathryn Birchall
- Kathy Stocks
- Katja Adie
- Katrina Klaasen
- Katrina McCormick
- Katrina McCormick
- Katy Dakin
- Kausic Chatterjee
- Kay Finney
- Kayleigh Collins
- Keir
- Keith Muir
- Kelechi Njoku
- Kelly Amor
- Kelly Chan
- Kelly Marie Shaw
- Kelly Thomas
- Kelly Waterfield
- Kelly Waterfield
- Kelvin Stewart
- Ken Fotherby
- Keniesha Miller
- Kerry Pettitt
- Kerstin Knops
- Kevin Dynan
- Kevin Thorpe
- Khaled Elfandi
- Khalid Azhar
- Khalid Rashed
- Khalil Ullah
- Kheng Xiong Ng
- Kim
- Kiranjit Bharaj
- Kirsten Harvey
- Kirsty Bond
- Kirsty Harkness
- Kirsty Jones
- Kneale Metcalf
- Krishna Patel
- Lakshmanan Sekaran
- Larissa Cuenoud
- Latheef Kalathil
- Laura Burgess
- Laura Codd
- Laura Gleave
- Laura Howaniec
- Laura Latter
- Laura Tucker
- Leanne Foote
- Leanne Quinn
- Li
- Lillian Choy
- Lily Mercer
- Linda Balian
- Linda Cowie
- Linda Dunn
- Linda Jackson
- Linda Lucas
- Linda MacLiver
- Lindsey Dow
- Linetty Makawa
- Lisa Clayton-Evans
- Lisa Hyatt
- Lisa Manning
- Lisa Wilson
- Lisa Wood
- Louise Gallagher
- Louise Harrison
- Louise Humphreys
- Louise Shaw
- Lourda Kerin
- Luci Crook
- Lucia Argandona
- Lucy Belle Guthrie
- Lucy Brotherton
- Lucy Coward
- Lucy Sykes
- Luke Barron
- Lukuman Gbadamoshi
- Lynda Connor
- Lynn Dinsmore
- Lynn Dixon
- Lynne Dacey
- Léjeune Gardener
- Magdalini Krommyda
- Mahesh Dhakal
- Mahmud Sajid
- Mairead Osborn
- Malik Hussain
- Man Yee Lam
- Mandy Couser
- Mandy Doherty
- Mandy Doherty
- Mandy Edwards
- Maneesh Bhargava
- Manju Krishnan
- Manohar Kini
- Maqsud Salehin
- Marc Randall
- Margaret Ball
- Margaret Tate
- Margi Godfrey
- Margo Henry
- Maria Bokhari
- Maria Brezitski
- Marie Weinling
- Marion Walker
- Marius Venter
- Mark Barber
- Mark Garside
- Mark McCarron
- Mark Wilkinson
- Mark Willmot
- Marketa Keltos
- Martin Cooper
- Martin James
- Martin Punter
- Mary Johnes
- Mary Kambafwile
- Mary MacLeod
- Matthew Robinson
- Maxwell
- Maxwell
- Meena Chauhan
- Meena Srinivasan
- Mehran
- Mehran Maanoosi
- Melanie Harrison
- Melinda Holden
- Mellor Zoe
- Michael Carpenter
- Michael Power
- Michaela Hooley
- Michele Tribbeck
- Michelle Bates
- Michelle Davis
- Michelle Fawcett
- Michelle Tayler
- Min Myint
- Miriam Harvey
- Mirriam Sangombe
- Mishell Cunningham
- Mmua Ngwako
- Mo Albazzaz
- Mohammad Haque
- Mohammad Irfan Alam
- Mohammad Khan
- Mohammad Nasar
- Mohammad Shahzad Iqbal
- Mohammed Moqsith
- Mohana Maddula
- Moore Sally
- MR Macleod
- MS Dennis
- Mudhar Abbdul-saheb
- Muhammad Naeem
- Muhammad Siddiq
- Murdina Bell
- Mushiya Mpelembue
- Mushtaq Wani
- N Sprigg
- Nabeela Nisar
- Naomi Jeyaraj
- Naomi Robinson
- Nasar Ahmad
- Natalie Atkinson
- Natalie Temple
- Natasha Clarke
- Natasha Schumacher
- Naval Shinh
- Naveen Gadapa
- Naweed Sattar
- Neetish Goorah
- Neha Chopra
- Neil Hunter
- Nenette Abano
- Niamh Hannon
- Niaz Mohammed
- Nic Weir
- Nichola Crouch
- Nichola Motherwell
- Nicholas Hunt
- Nicola Butterworth-Cowin
- Nicola Chapman
- Nicola Day
- Nicola Devitt
- Nicola Gainsborough
- Nicola Gilzeane
- Nicola Persad
- Nigel Smyth
- Nikhil Majmudar
- Nikhil Sharma
- Nikki Gautam
- Nilofer Dayal
- Nina Francia
- Nisha Menon
- Nnebuife Oji
- Olesia Balitska
- Olga Balazikova
- Oliver Matias
- Olivia Geraghty
- Omid Halse
- Outi Quinn
- Owen David
- Ozlem Redjep
- PAG Sandercock
- Pam Crawford
- Pasquini
- Pat Taylor
- Patrick Sutton
- Paul Findlay
- Paul Fitzsimmons
- Paul Guyler
- Paul Mudd
- Paul Nicholas
- Paula Lopez
- Paula Owings
- Pauli Walker
- Pauline Baker
- Pauline Bayliss
- Pauline Brown
- Pauline Fitzell
- Pauline Weir
- Penelope Cox
- Perry
- Peter Howard
- Peter Langhorne
- Peter Murphy
- Peter Owusu-Agyei
- Peter Slade
- Peter Wilding
- Philip Mathieson
- Philip Poku
- Philip Thomas
- Philip Thompson
- Phillip Ferdinand
- PM White
- Poon
- Prabal Datta
- Pradeep Kumar
- Prasad Siddegowda
- Pratap Rana
- Priya Bhatnagar
- Procter Sarah
- Procter Sarah
- Puneet Dangri
- Puneet Kakar
- Rachael Jones
- Rachel Crown
- Rachel Evans
- Rachel Gallifent
- Rachel Gascoyne
- Rachel Glover
- Rachel Hayman
- Rachel Teal
- Racquel Carpio
- Radim Licenik
- Raj Shekhar
- Rajalakshmi Orath Prabakaran
- Rajaram Bathula
- Rajendra Yadava
- Ralf Lindert
- Ramesh Durairaj
- Ramesh Krishnamurthy
- Rangah Niranchanan
- Ranjan Sanyal
- Ratneshwari Jha
- Rayessa Rayessa
- Razik Fathima
- Rebecca Butler
- Rebecca Clarke
- Rebecca Grue
- Rebecca Wallace
- Rebecca Wallace
- Rebecca Williams
- Rebekah Perfitt
- Rehana Bakawala
- Rekha Keshvara
- Renuka Erande
- Resti Varquez
- Richard Davey
- Richard Dewar
- Richard Donnelly
- Richard Greenwood
- Richard Miller
- Richard O'Brien
- Richard O'Brien
- Richard Parker
- Rina Mardania
- Rita Ghatala
- Robert Ballantine
- Robert Campbell
- Robert Luder
- Robert Whiting
- Robyn Creeden
- Rohan Simon
- Rosanna Fong
- Rosemary Anderson
- Rowilson Jarapa
- Rustam Al-Shahi Salman
- Ruth Bellfield
- Ruth Davies
- Ruth Fennelly
- Ruth Fraser
- Ruth Fraser
- Ruth Graham
- Ruth Paulton
- Ruwan Parakramawansha
- Sagal Kullane
- Sageet Amlani
- Saikat Dhar
- Saima Sheikh
- Saira Sattar
- Sajjad Anwar
- Sakthivel Sethuraman
- Sally Marshall
- Sally Moseley
- Salwa El Tawil
- Sam Ellis
- Sam King
- Samantha Clarke
- Samantha Keenan
- Samantha Seagrave
- Samantha Stafford
- Samantha Stafford
- Sammie Qureshi
- Sandeep Ankolekar
- Sandip Ghosh
- Sandra Leason
- Sandra Nelson
- Sankaranarayanan Ramachandran
- Santhosh Subramonian
- Sarah Board
- Sarah Brown
- Sarah Caine
- Sarah Crisp
- Sarah Cuddy
- Sarah Finlay
- Sarah Horton
- Sarah O'Toole
- Sarah Ross
- Sarah Stevenson
- Sarah Thomas
- Sarah Thornthwaite
- Sarah Trippier
- Sarah Wilson
- Sean Mcauley
- Senthil Raghunathan
- Seona Burgess
- Shagufta Khan
- Shahrzad Shahmehri
- Shanni McDonald
- Shannon Amoils
- Sharon Johnson
- Sharon Storton
- Sharon Tysoe
- Sheila Mashate
- Sheila Nyabadza
- Shelley Treadwell
- Shez Feerick
- Shrivakumar Krishnamoorthy
- Shuja Punekar
- Shuna Egerton
- Shyam Kelavkar
- Silvie Davies
- Simon Hervey
- Simon Sharpe
- Simon Smith
- Simone Ivatts
- Sindhu Rashmi
- Siobhan Kelly
- Sissy Ispoglou
- Skarlet Markova
- Skelton Miriam
- Sofia Dima
- Sonia Raj
- Sophie Newton
- Sreeman Andole
- Srikanth Chenna
- Stacey Valentine
- Stefan Schwarz
- Steiner
- Steinhubl
- Stephanie Jones
- Stephanie Lee
- Stephanie McCann
- Stephanie Stevens
- Stephen Duberley
- Stephen Woodward
- Steve Buckle
- Steve Buckle
- Stuart Maguire
- Stuart Symonds
- Sue Evans
- Sue Lyjko
- Suheil Ponnambath
- Suja Cherian
- Sujata Blane
- Sulaiman Sultan
- Susan Clayton
- Susan Crawford
- Susan Downham
- Susan Maiden
- Susan McDonald
- Susan O'Connell
- Susan Pound
- Susan Szabo
- Susan Thompson
- Susan Tucker
- Susan White
- Susannah Walker
- Suzanne Lucas
- Suzanne Ragab
- Suzanne Tauro
- Swapna Kunhunny
- Sweni Shah
- Syed Haider
- Tajammal Zahoor
- Talal Al-Mayhani
- Talat Anjum
- Tanya Ingram
- Tara Lawrence
- Tarn Nozedar
- Tatiana Garcia
- Tatjana Roganova
- Temi Adedoyin
- Teo
- Teresa Beaty
- Teresa Thompson
- Terry Jones
- Thayalini Loganathan
- Thomas Gattringer
- Thomas Harrison
- Tim Cassidy
- Timothy England
- Timothy Webster
- Toby Black
- Tolu Adesina
- Tom Hughes
- Tom Webb
- Tony Rudd
- Tracey Cosier
- Tracey Dobson
- Tracy Fuller
- Tracy Marsden
- Tressy Pitt-Kerby
- Una Poultney
- Ursula Schulz
- Usman Khan
- Uzma Khan
- Val Jones
- Valerie Gott
- Valerie Hogg
- van Asch
- Vanessa Pressly
- Varthi Sukdeo
- Vasileios Papavasileiou
- Venetia Vettimootal Johnson
- Vera Cvoro
- Vicky Taylor
- Victoria Adell
- Victoria Little
- Victoria O'Loughlin
- Victoria Sutton
- Victoria Tilley
- Vidya Baliga
- Vinh Nguyen
- Vinodh Krishnamurthy
- Wilma Smith
- WN Whiteley
- Wong
- Wood
- Xuya Huang
- Yasmin Harrington-Davies
- Yogish Joshi
- Yogish Pai
- Yolanda Baird
- Zhe Law
- Zin Naing
- Publication venue
- 'Elsevier BV'
- Publication date
- 21/05/2019
- Field of study
BACKGROUND: Antiplatelet therapy reduces the risk of major vascular events for people with occlusive vascular disease, although it might increase the risk of intracranial haemorrhage. Patients surviving the commonest subtype of intracranial haemorrhage, intracerebral haemorrhage, are at risk of both haemorrhagic and occlusive vascular events, but whether antiplatelet therapy can be used safely is unclear. We aimed to estimate the relative and absolute effects of antiplatelet therapy on recurrent intracerebral haemorrhage and whether this risk might exceed any reduction of occlusive vascular events. METHODS: The REstart or STop Antithrombotics Randomised Trial (RESTART) was a prospective, randomised, open-label, blinded endpoint, parallel-group trial at 122 hospitals in the UK. We recruited adults (≥18 years) who were taking antithrombotic (antiplatelet or anticoagulant) therapy for the prevention of occlusive vascular disease when they developed intracerebral haemorrhage, discontinued antithrombotic therapy, and survived for 24 h. Computerised randomisation incorporating minimisation allocated participants (1:1) to start or avoid antiplatelet therapy. We followed participants for the primary outcome (recurrent symptomatic intracerebral haemorrhage) for up to 5 years. We analysed data from all randomised participants using Cox proportional hazards regression, adjusted for minimisation covariates. This trial is registered with ISRCTN (number ISRCTN71907627). FINDINGS: Between May 22, 2013, and May 31, 2018, 537 participants were recruited a median of 76 days (IQR 29-146) after intracerebral haemorrhage onset: 268 were assigned to start and 269 (one withdrew) to avoid antiplatelet therapy. Participants were followed for a median of 2·0 years (IQR [1·0- 3·0]; completeness 99·3%). 12 (4%) of 268 participants allocated to antiplatelet therapy had recurrence of intracerebral haemorrhage compared with 23 (9%) of 268 participants allocated to avoid antiplatelet therapy (adjusted hazard ratio 0·51 [95% CI 0·25-1·03]; p=0·060). 18 (7%) participants allocated to antiplatelet therapy experienced major haemorrhagic events compared with 25 (9%) participants allocated to avoid antiplatelet therapy (0·71 [0·39-1·30]; p=0·27), and 39 [15%] participants allocated to antiplatelet therapy had major occlusive vascular events compared with 38 [14%] allocated to avoid antiplatelet therapy (1·02 [0·65-1·60]; p=0·92). INTERPRETATION: These results exclude all but a very modest increase in the risk of recurrent intracerebral haemorrhage with antiplatelet therapy for patients on antithrombotic therapy for the prevention of occlusive vascular disease when they developed intracerebral haemorrhage. The risk of recurrent intracerebral haemorrhage is probably too small to exceed the established benefits of antiplatelet therapy for secondary prevention. FUNDING: British Heart Foundation
And How Are We Supposed to Pay for Health Care? Views of the Poor and the Near Poor on Welfare Reform
- Author
- Publication venue
- 'University of California Press'
- Publication date
- Field of study