39 research outputs found

    Overview of Coronary Artery Disease

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    Telemonitoring of the Pacemakers

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    Practical Approach to Chest Pain Related to Cardiac Implantable Electronic Device Implantation

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    In this review article, we described the common causes and approach for chest pain that happens after cardiac device implantation surgeries. We also describe the clinical features and appropriate treatment for them

    ECG Approach to Narrow QRS Complex Supraventricular Tachycardia

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    Supraventricular tachycardia (SVT) is an irregular heart rhythm in which the focus of impulse lies above the bundle of His, i.e., the sinus node, the atria, and the atrioventricular node (AVN). There are two types of SVT: Narrow QRS complex tachycardia and wide QRS complex tachycardia. Narrow QRS complexe tachycardias can further be divided as regular or irregular based on R鈥揜 intervals. There is further classification that can be made in regular rhythms in terms of RP interval. The most common tachycardias that are characterized by a long RP interval include sinus tachycardia, atrial tachycardia, and atrioventricular reentrant tachycardia. Short RP interval tachycardias mainly Atrioventricular nodal reentrant tachycardia (AVNRT), junctional tachycardia (JT) and permanent junctional reciprocating tachycardia (PJRT). On the other hand, irregular SVTs usually include atrial fibrillation, atrial flutter, and multifocal atrial tachycardia

    Corrected QT interval as a predictor of mortality in elderly patients with syncope

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    Background: Prolonged corrected QT interval (QTc) holds independent prognostic importance in predicting mortality in patients with coronary artery disease, diabetes mellitus and congestive heart failure. However, its association with all cause or cardiac mortality in the general population remains unclear. We evaluated the relationship between prolonged QTc and total mortality among patients with syncope. Methods: This was a retrospective study of 348 patients presenting to the emergency department with syncope of any etiology over a period of one year. All patients with atrial fibrillation, left bundle branch block and cardiac devices (pacemaker/defibrillator) were excluded. Prolonged QTc interval was defined as QTc interval ≥ 440 ms. The primary end point for this study was total mortality in patients presenting with syncope. Results: There were 58 (16%) deaths in this population during a mean follow-up of 30 months. Patients with prolonged QTc interval had significantly higher mortality when compared to those with normal QTc interval (22% vs 11%; p = 0.004). This significance was not retained after adjustment for covariates in the Cox regression model, where we found that age ≥ 65 years (hazard ratio [HR] 7.9; 95% confidence interval [CI] 1.9–32.9; p = 0.004) and QTc interval ≥ 500 ms (HR 3.5; 95% CI 1.56–8.12; p = 0.002) were predictors of increased mortality among patients with syncope. Conclusions: In elderly patients presenting to the emergency department with syncope, QTc interval ≥ 500 ms helps identify patients at higher risk of adverse outcomes. (Cardiol J 2011; 18, 4: 395–400

    Infantile free sialic acid storage disease presenting as non-immune hydrops fetalis

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    A preterm, 33 weeks of gestational age, was antenatally diagnosed with hydrops fetalis. There is positive family history of two early neonatal death of unknown cause on his maternal side. He had generalized edema, massive ascites, blonde hair, unexpectedly fair skin, coarse facies, telangiectasia over the trunk, abdomen, and face. Abdominal paracentesis showed no urine, no bilirubin and no chylous fluid. Several clinical investigations ruled out the most common diagnoses. Finally, genetic analysis by whole exome sequencing showed a homozygous splicing site c.979-1G>T mutation in SLC17A5 gene causing infantile free sialic acid storage disease. Both parents were found to be heterozygous. Despite all supportive measurements, the baby died at the age of 6 months

    Skorygowany odst臋p QT jako czynnik prognostyczny zgonu w grupie os贸b w podesz艂ym wieku z omdleniem w wywiadzie

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    Wst臋p: Wyd艂u偶ony odst臋p QT (QTc) jest niezale偶nym czynnikiem prognostycznym wzmo偶onej 艣miertelno艣ci w grupie os贸b obci膮偶onych chorob膮 wie艅cow膮, cukrzyc膮 i zastoinow膮 niewydolno艣ci膮 serca. Jego zwi膮zek z mechanizmami wszystkich zgon贸w z przyczyn sercowo-naczyniowych w populacji og贸lnej pozostaje niejasny. W niniejszej pracy wykazano zale偶no艣膰 mi臋dzy wyd艂u偶onym odst臋pem QT a ca艂kowit膮 艣miertelno艣ci膮 w grupie os贸b z omdleniami. Metody: Badaniem retrospektywnie obj臋to grup臋 348 pacjent贸w, kt贸rzy zg艂osili si臋 na oddzia艂 ratunkowy z powodu omdlenia z jakiejkolwiek przyczyny w ci膮gu ostatniego roku. Wykluczono osoby z migotaniem przedsionk贸w, blokiem lewej odnogi p臋czka Hisa oraz pacjent贸w z implantowanymi urz膮dzeniami, jak stymulator/kardiowerter-defibrylator. Wyd艂u偶ony odst臋p QT zdefiniowano jako trwaj膮cy co najmniej 440 ms. Pierwszorz臋dowy punkt ko艅cowy w badanej grupie os贸b z omdleniami stanowi艂 zgon. Wyniki: W obserwacji 30-miesi臋cznej odnotowano 58 zgon贸w (16%). W grupie pacjent贸w z wyd艂u偶onym odst臋pem QT odsetek zgon贸w by艂 znacznie wy偶szy ni偶 w grupie z prawid艂owym odst臋pem (22% v. 11%; p = 0,004). Ta istotno艣膰 nie zosta艂a podtrzymana po dodaniu kowariancji w modelu regresji Coxa, gdzie wiek 65 lat i wi臋cej [hazard wzgl臋dny (HR) 7,9; 95-procentowy przedzia艂 ufno艣ci (CI) 1,9–32,9; p = 0,004] i odst臋p QTc wynosz膮cy co najmniej 500 ms (HR 3,5; 95% CI 1,56–8,12; p = 0,002) 艂膮cznie by艂y wska藕nikami prognostycznymi zgonu w grupie pacjent贸w z omdleniami. Wnioski: W grupie starszych os贸b zg艂aszaj膮cych si臋 na oddzia艂 ratunkowy z powodu omdlenia odst臋p QT ≥ 500 ms pozwala pom贸c zidentyfikowa膰 pacjent贸w z grupy ryzyka wyst膮pienia nag艂ego incydentu sercowego. (Folia Cardiologica Excerpta 2011; 6, 4: 211–216

    withdrawn 2017 hrs ehra ecas aphrs solaece expert consensus statement on catheter and surgical ablation of atrial fibrillation

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    Cardiac Arrhythmias

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    This book is a comprehensive and practical updated review about the various aspects of cardiac arrhythmias. It covers a variety of aspects of both atrial and nonatrial arrhythmias, including genetics, clinical aspects, ECG manifestations, and practical approaches to complex cardiac arrhythmia management - office, hospital, intensive care unit, electrophysiology laboratory, and operating room. This book also presents comprehensive ECG reviews of cardiac arrhythmias like atrial flutter, Brugada pattern, Breijo ECG pattern, and PVCs. Practical aspects of preventing and managing arrhythmias - central venous catheter-induced, atrial flutter, and drug-induced cardiac arrhythmias - are described. Experts have demonstrated the approach for mapping and ablation of complex arrhythmias like atrial flutter, idiopathic ventricular tachycardia, and Brugada syndrome
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