19 research outputs found
Characterization of proteins from human synovium and mononuclear leucocytes that induce resorption of cartilage proteoglycan in vitro
- Publication venue
- 'Portland Press Ltd.'
- Publication date
- Field of study
Pig catabolin is a form of interleukin 1. Cartilage and bone resorb, fibroblasts make prostaglandin and collagenase, and thymocyte proliferation is augmented in response to one protein
- Publication venue
- 'Portland Press Ltd.'
- Publication date
- Field of study
Prognostic model to predict postoperative acute kidney injury in patients undergoing major gastrointestinal surgery based on a national prospective observational cohort study.
- Author
- Aamir A
- Abbas J
- Abbas N
- Abbott TEF
- Abdalla M
- Abdikadir H
- Abuhussein N
- Acquaah F
- Adamson R
- Adeleye O
- Adeogun A
- Adlan A
- Aftab R
- Afzal Z
- Agarwal M
- Aglan H
- Agnew CJF
- Agrawal R
- Ahern D
- Ahluwalia J
- Ahluwalia V
- Ahmad A
- Ahmad K
- Ahmed H
- Ahmed I
- Ahmed L
- Ahmed N
- Ahmed P
- Ainger E
- Ainsworth P
- Aishwarya G
- Ajibola-Taylor O
- Akhbari M
- Akhtar A
- Akhtar R
- Akpenyi O
- Al-Ausi M
- Al-Huneidi R
- Al-Khudairi R
- Al-Masri S
- Al-Mousawi A
- Al-Saadi N
- Alagappan A
- Alberts J
- Alfa-Wali M
- Ali A
- Ali B
- Ali I
- Ali M
- Ali Q
- Ali S
- Alturki N
- Alwandi A
- Amani L
- Amarnath T
- Amer M
- Amin H
- Amin MN
- Amoah R
- Amoah-Arko A
- Anandarajah C
- Ananthavarathan P
- Andah EJE
- Andrew K
- Andrews H
- Ang A
- Ang HL
- Ang JJ
- Ani C
- Anilkumar A
- Anto N
- Anwar S
- Apperley H
- Appleton S
- Aquilina T
- Archer M
- Arif T
- Arneill M
- Arnell S
- Arnold TJ
- Arshad A
- Arthur J
- Arulkumaran N
- Arya J
- Asad M
- Asemota N
- Ashaye T
- Ashdown T
- Ashour R
- Ashraf MR
- Ashwood J
- Asif U
- Atkin G
- Atkins B
- Attalla M
- Aubrey-Jones D
- Auckburally S
- Auld F
- Auluck I
- Azam S
- Aziz R
- Azizi A
- Azmi F
- Babatunde F
- Babu VS
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- STARSurg Collaborative Writing Committee, Data analysis, Steering committee, Advisory group, Regional leads, Collaborators and validators
- STARSurg Collaborative Writing Committee, Data analysis, Steering committee, Advisory group, Regional leads, Collaborators and validators, Nepogodiev, D
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- Zubikarai G
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- Publication venue
- 'Wiley'
- Publication date
- 18/05/2018
- Field of study
Background: Acute illness, existing co-morbidities and surgical stress response can all contribute to postoperative acute kidney injury (AKI) in patients undergoing major gastrointestinal surgery. The aim of this study was prospectively to develop a pragmatic prognostic model to stratify patients according to risk of developing AKI after major gastrointestinal surgery. Methods: This prospective multicentre cohort study included consecutive adults undergoing elective or emergency gastrointestinal resection, liver resection or stoma reversal in 2-week blocks over a continuous 3-month period. The primary outcome was the rate of AKI within 7 days of surgery. Bootstrap stability was used to select clinically plausible risk factors into the model. Internal model validation was carried out by bootstrap validation. Results: A total of 4544 patients were included across 173 centres in the UK and Ireland. The overall rate of AKI was 14·2 per cent (646 of 4544) and the 30-day mortality rate was 1·8 per cent (84 of 4544). Stage 1 AKI was significantly associated with 30-day mortality (unadjusted odds ratio 7·61, 95 per cent c.i. 4·49 to 12·90; P < 0·001), with increasing odds of death with each AKI stage. Six variables were selected for inclusion in the prognostic model: age, sex, ASA grade, preoperative estimated glomerular filtration rate, planned open surgery and preoperative use of either an angiotensin-converting enzyme inhibitor or an angiotensin receptor blocker. Internal validation demonstrated good model discrimination (c-statistic 0·65). Discussion: Following major gastrointestinal surgery, AKI occurred in one in seven patients. This preoperative prognostic model identified patients at high risk of postoperative AKI. Validation in an independent data set is required to ensure generalizability
Scintigraphic abnormalities of the pelvic region in horses examined because of lameness or poor performance: 128 cases (1993–2000)
- Author
- Publication venue
- 'American Veterinary Medical Association (AVMA)'
- Publication date
- Field of study
The application of a scintigraphic grading system to equine tibial stress fractures: 42 cases
- Author
- Publication venue
- 'Wiley'
- Publication date
- Field of study
Thigh-length compression stockings and DVT after stroke
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- Publication venue
- 'Elsevier BV'
- Publication date
- 01/07/1994
- Field of study
Controversy exists as to whether neoadjuvant chemotherapy improves survival in patients with invasive bladder cancer, despite randomised controlled trials of more than 3000 patients. We undertook a systematic review and meta-analysis to assess the effect of such treatment on survival in patients with this disease
Descriptive epidemiology of joint injuries in Thoroughbred racehorses in training.
- Author
- Publication venue
- 'Wiley'
- Publication date
- Field of study
The efficacy of dantrolene sodium in controlling exertional rhabdomyolysis in the Thoroughbred racehorse
- Author
- Publication venue
- 'Wiley'
- Publication date
- Field of study
The effect of calcium channel blockers and calmodulin inhibitors on the macrophage factor-stimulated synthesis of collagenase by rabbit chondrocytes
- Author
- A. B. Stavisty
- A. E. Postlethwaite
- A. L. Oronsky
- B. Wright
- C. E. Brinckerhoff
- C. E. Brinckerhoff
- C. E. Gathright
- C. Peeters-Joris
- E. D. Harris Jr.
- E. E. Golds
- E. Wojtecka-Lukasik
- G. DiPasquale
- G. M. Kammer
- H. J. Richardson
- J. Aggeler
- J. B. McCarthy
- J. C. Nolan
- J. C. Nolan
- J. L. Seltzer
- J. M. Dayer
- J. M. Dayer
- J. M. Dayer
- J. M. Dayer
- L. E. Wagner
- L. M. C. Pilsworth
- M. T. Gisslow
- N. Moskowitz
- P. A. McCroskery
- P. D. Benya
- P. Hasselbacher
- R. J. Smith
- S. B. Mizel
- S. C. Ridge
- S. M. Krane
- S. M. Wahl
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Aspiration and Inspiration: Student Motives in Adult Residential Colleges
- Author
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study