Diseño de un modelo para evaluar la accesibilidad web y validación sobre un ranking de las universidades españolas

This paper presents a study of the websites of the Spanish universities, and the design of a quantitative metric for measuring their level of accessibility, in order to establish a ranking that can be used for evaluate and compare them. This study considered the website of 79 Spanish universities; they have been analyzed by measuring some web accessibility-related indicators, such as accessibility and standards guidelines compliance, compatibility, usability errors, etc. With the obtained results and the proposed metric, we have developed a ranking of universities that measure their web accessibility quality. The main goal of this paper is presenting the results of this study.Se presenta un estudio sobre los sitios Web de las universidades españolas, y el diseño de una medida cuantitativa para medir su nivel de accesibilidad, con objeto de establecer un ranking que permita evaluarlas y compararlas entre sí. En este estudio se han considerado 79 universidades españolas, cuyos sitios web institucionales se han analizado en profundidad midiendo diversos indicadores relacionados con la accesibilidad web, tales como la satisfacción de estándares y directrices de accesibilidad, la compatibilidad con distintos navegadores, errores de usabilidad, etc. A partir de los resultados obtenidos y con la métrica propuesta, se ha elaborado un ranking de universidades que pretende medir la calidad de sus sitios institucionales en cuanto a accesibilidad web. El objetivo del presente trabajo es presentar los resultados obtenidos a partir de dicho estudio

El Canal de Cultura Contemporánea de las Universidades Públicas de Andalucía: mejoras y experiencias

The Contemporary Culture Channel of Andalusian Public Universities (CaCoCu) is a web platform with cultural contents, that basically contains audiovisual recordings of diverse cultural activities. CaCoCu was first presented in 2007 and has currently an important collection of documents. This paper describes its current state, the technological innovations that have recently been developed and the adaptation of the platform to adopt new vídeo standards, a better representation of knowledge, and the methodologies used for the dissemination of the channel through social networks.El Canal de Cultura Contemporánea de las Universidades Públicas de Andalucía (CaCoCu) consiste en una plataforma web con contenido cultural, fundamentalmente grabaciones audiovisuales íntegras de diversas actividades. CaCoCu se puso en explotación en 2007 y actualmente cuenta con un importante fondo documental. En este trabajo se describe el estado actual, las innovaciones tecnológicas que se han incorporado recientemente y su adaptación para nuevos estándares y una mejor representación del conocimiento, así como la metodología utilizada para la difusión del mismo mediante redes sociales

Large expert-curated database for benchmarking document similarity detection in biomedical literature search

Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical research.Peer reviewe

The James Webb Space Telescope Mission

Twenty-six years ago a small committee report, building on earlier studies, expounded a compelling and poetic vision for the future of astronomy, calling for an infrared-optimized space telescope with an aperture of at least $4m$. With the support of their governments in the US, Europe, and Canada, 20,000 people realized that vision as the $6.5m$ James Webb Space Telescope. A generation of astronomers will celebrate their accomplishments for the life of the mission, potentially as long as 20 years, and beyond. This report and the scientific discoveries that follow are extended thank-you notes to the 20,000 team members. The telescope is working perfectly, with much better image quality than expected. In this and accompanying papers, we give a brief history, describe the observatory, outline its objectives and current observing program, and discuss the inventions and people who made it possible. We cite detailed reports on the design and the measured performance on orbit.Comment: Accepted by PASP for the special issue on The James Webb Space Telescope Overview, 29 pages, 4 figure

A novel ultra-low phase noise, programmable frequency multiplier-by-30 architecture. Application to 60-GHz frequency generation

International audienc

Development of Soft-Computing techniques capable of diagnosing Alzheimer's Disease in its pre-clinical stage combining MRI and FDG-PET images

Abstract. In this paper an intelligent classifier was development, in which information provided from MRI and FDG-PET images are combined in order to obtain an automatic classifier. In the first step was to develop a classification method to tag simultaneously MR and FDG-PET images as either normal or with the Alzheimer's disease (AD). With the methodology obtained, and using similar features, the next step was the identification and classification in normal subjects, MCI (Middle Cognitive Impairment) patients and AD patients. The last step was the possibility to classify in Middle Cognitive Impairment Converters (MCI-C, i. e. , people that suffer a MCI and in the future will suffer from Alzheimer's disease within 18 months), and Middle Cognitive Impairment Non Converters (MCI-NC, i. e., people that suffer a MCI and in the future will not suffer from Alzheimer's disease). It is noteworthy that with this last study we could offer a tool to assist the early diagnosis of dementia

Nursery fertilization enhances survival and physiological status in Canary Island pine (Pinus canariensis) seedlings planted in a semiarid environment

We tested the hypothesis that fertilized containerized Pinus canariensis seedlings increases survival when planted in semiarid sites through the improvement of their physiological status during the establishment phase by an increment in root growth. Seedlings were cultured under two different regimes: traditional (in non-fertilized natural soil) and alternative (in fertilized peat). Morphological attributes and nitrogen content were measured before planting. Measurements of survival and growth in the plantation were made periodically for 2 years and physiological plant responses (leaf water potential, gas exchange and chlorophyll fluorescence) during the third summer after planting were tested and finally a set of plants were excavated to measure the same parameters as before planting. Seedlings cultivated using fertilized peat achieved the highest values for all of evaluated parameters. During the third dry season, big seedlings exhibited better physiological status. Therefore, enhanced root growth can result in better water uptake during the dry period thereby increasing survival and growth in the next few years after planting. A feed-back physiological model is proposed to explain P. canariensis establishment in a semiarid environment

Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19

BackgroundWe previously reported that impaired type I IFN activity, due to inborn errors of TLR3- and TLR7-dependent type I interferon (IFN) immunity or to autoantibodies against type I IFN, account for 15-20% of cases of life-threatening COVID-19 in unvaccinated patients. Therefore, the determinants of life-threatening COVID-19 remain to be identified in similar to 80% of cases.MethodsWe report here a genome-wide rare variant burden association analysis in 3269 unvaccinated patients with life-threatening COVID-19, and 1373 unvaccinated SARS-CoV-2-infected individuals without pneumonia. Among the 928 patients tested for autoantibodies against type I IFN, a quarter (234) were positive and were excluded.ResultsNo gene reached genome-wide significance. Under a recessive model, the most significant gene with at-risk variants was TLR7, with an OR of 27.68 (95%CI 1.5-528.7, P=1.1x10(-4)) for biochemically loss-of-function (bLOF) variants. We replicated the enrichment in rare predicted LOF (pLOF) variants at 13 influenza susceptibility loci involved in TLR3-dependent type I IFN immunity (OR=3.70[95%CI 1.3-8.2], P=2.1x10(-4)). This enrichment was further strengthened by (1) adding the recently reported TYK2 and TLR7 COVID-19 loci, particularly under a recessive model (OR=19.65[95%CI 2.1-2635.4], P=3.4x10(-3)), and (2) considering as pLOF branchpoint variants with potentially strong impacts on splicing among the 15 loci (OR=4.40[9%CI 2.3-8.4], P=7.7x10(-8)). Finally, the patients with pLOF/bLOF variants at these 15 loci were significantly younger (mean age [SD]=43.3 [20.3] years) than the other patients (56.0 [17.3] years; P=1.68x10(-5)).ConclusionsRare variants of TLR3- and TLR7-dependent type I IFN immunity genes can underlie life-threatening COVID-19, particularly with recessive inheritance, in patients under 60 years old