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Impact of cross-section uncertainties on supernova neutrino spectral parameter fitting in the Deep Underground Neutrino Experiment

Author: Abi B.
Abud A. Abed
Acciarri R.
Acero M. A.
Adames M. R.
Adamov G.
Adamowski M.
Adams D.
Adinolfi M.
Adriano C.
Aduszkiewicz A.
Aguilar J.
Ahmad Z.
Ahmed J.
Aimard B.
Akbar F.
Alba J. L. L. Bazo
Allison K.
Alonso M. J. Rodriguez
Alrashed M.
Alton A.
Alvarez R.
Alzás P. Barham
Amedo P.
Anderson J.
Andrade D. A.
Andreopoulos C.
Andreotti M.
Andrews M. P.
Andrianala F.
Andringa S.
Anfimov N.
Ankowski A.
Antoniassi M.
Antonova M.
Antoshkin A.
Aranda-Fernandez A.
Arellano L.
Arnold L. O.
Arroyave M. A.
Asaadi J.
Ashkenazi A.
Asquith L.
Astiz I. L. De Icaza
Atkin E.
Auguste D.
Aurisano A.
Aushev V.
Autiero D.
Ayala-Torres M.
Azfar F.
Back A.
Back H.
Back J. J.
Bagaturia I.
Bagby L.
Balashov N.
Balasubramanian S.
Baldi P.
Baldini W.
Baller B.
Bambah B.
Banerjee R.
Barao F.
Barenboim G.
Barker G. J.
Barkhouse W.
Barnes C.
Barr G.
Barrios J. Hoyos
Barros A.
Barros N.
Barrow J. L.
Basharina-Freshville A.
Bashyal A.
Basque V.
Batchelor C.
Battat J. B. R.
Battisti F.
Bay F.
Bazetto M. C. Q.
Beacom J. F.
Bechetoille E.
Behera B.
Belchior E.
Bell G.
Bellantoni L.
Bellettini G.
Bellini V.
Beltramello O.
Benekos N.
Benitez A. Campos
Benjamin D.
Berger J.
Berkman S.
Bermeo L. V. Gomez
Bernardini P.
Berner R. M.
Bersani A.
Bertolucci S.
Betancourt M.
Bevan A.
Bezawada Y.
Bezerra A. T.
Bezerra T. J.
Bhambure J.
Bhardwaj A.
Bhatnagar V.
Bhattacharjee M.
Bhattacharya M.
Bhattarai D.
Bhuller S.
Bhuyan B.
Biagi S.
Bian J.
Biery K.
Bilki B.
Bishai M.
Bitadze A.
Blake A.
Blaszczyk F. D.
Blazey G. C.
Blend D.
Blucher E.
Boissevain J.
Bolognesi S.
Bolton T.
Bomben L.
Bonesini M.
Bonilla-Diaz C.
Bonini F.
Booth A.
Boran F.
Bordoni S.
Borkum A.
Bostan N.
Bour P.
Bracinik J.
Braga D.
Brailsford D.
Branca A.
Brandt A.
Bravo-Moreno M.
Bremer J.
Brew C.
Brice S. J.
Brio V.
Brizzolari C.
Bromberg C.
Brooke J.
Bross A.
Brunetti G.
Brunetti M.
Buchanan N.
Budd H.
Bueno L. Molina
Buergi J.
Cagnoli I.
Cai T.
Caicedo D. A. Martinez
Caiulo D.
Calabrese R.
Calafiura P.
Calcutt J.
Calin M.
Calivers L.
Calvez S.
Calvo E.
Caminata A.
Campanelli W. L. Anicézio
Caratelli D.
Carber D.
Carceller J. M.
Carini G.
Carlus B.
Carneiro M. F.
Carniti P.
Carranza H.
Carrara N.
Carroll L.
Carroll T.
Carter A.
Castillo A.
Castromonte C.
Catano-Mur E.
Cattadori C.
Cavalier F.
Cavallaro G.
Cavanna F.
Centro S.
Cerati G.
Cervelli A.
Chakraborty K.
Chalifour M.
Chappell A.
Chardonnet E.
Charitonidis N.
Chatterjee A.
Chattopadhyay S.
Chauhan S. Singh
Chen H.
Chen M.
Chen Y.
Chen-Wishart Z.
Cheon Y.
Cherdack D.
Chi C.
Childress S.
Chirco R.
Chiriacescu A.
Chitirasreemadam N.
Cho K.
Choate S.
Chokheli D.
Chong P. S.
Chowdhury B.
Christensen A.
Christian D.
Christodoulou G.
Chukanov A.
Chung M.
Church E.
Cicero V.
Clapa D.
Clarke P.
Cline G.
Coan T. E.
Cocco A. G.
Coelho J. A. B.
Cohen A.
Collot J.
Conley E.
Conrad J. M.
Convery M.
Cooke P.
Copello S.
Corchado S. Manthey
Cova P.
Cox C.
Cremaldi L.
Cremonesi L.
Crespo-Anadón J. I.
Crisler M.
Cristaldo E.
Crnkovic J.
Crone G.
Cross R.
Cudd A.
Cuesta C.
Cui Y.
Cussans D.
da Motta H.
Dai J.
Dalager O.
Dallavalle R.
Dar Z. A.
Darby R.
David C.
David Q.
Davies G. S.
Davini S.
Dawson J.
De Aguiar R.
De Almeida P.
De Bonis I.
de Gouvêa A.
De Holanda P. C.
De Jong P.
De la Torre A.
De Leo V.
De Lurgio P.
de Oliveira M. A. Leigui
De Roeck A.
De Romeri V.
De Souza G.
de Souza H. Vieira
De K.
De S.
Debbins P.
Decowski M. P.
Deisting A.
Delbart A.
Delepine D.
Delgado M.
Delgado M. A. Ramirez
Dell'Acqua A.
Delmonte N.
DeMuth D. M.
Dennis S.
Densham C.
Denton P.
Deptuch G. W.
Detje J. P.
Devi R.
Devine J.
Dharmapalan R.
Di Capua F.
Di Domenico A.
Di Domizio S.
Di Falco S.
Di Giulio L.
Di Noto L.
Dias M.
Ding P.
Diociaiuti E.
Distefano C.
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Diwan M.
Djurcic Z.
Doering D.
Dolan S.
Dolek F.
Dolinski M. J.
Domenici D.
Domine L.
Donati S.
Donon Y.
Doran S.
Douglas D.
Dragone A.
Drielsma F.
Duarte L.
Duchesneau D.
Duffy K.
Dugas K.
DUNE Collaboration
Dunne P.
Dutta B.
Duyang H.
Dvornikov O.
Dwyer D. A.
Dyshkant A. S.
Díaz F.
Díaz J. S.
Eads M.
Earle A.
Edayath S.
Edmunds D.
Eisch J.
Emberger L.
Englezos P.
Ereditato A.
Erjavec T.
Escobar C. O.
Evans J. J.
Ewart E.
Ezeribe A. C.
Fahey K.
Fajardo L. S. Gomez
Fajt L.
Falcone A.
Fani' M.
Farnese C.
Farzan Y.
Fedoseev D.
Felix J.
Feng Y.
Fernandez-Martinez E.
Ferraro F.
Ferreira G. Ruiz
Ferry G.
Fields L.
Filip P.
Filkins A.
Filthaut F.
Fine R.
Fiorillo G.
Fiorini M.
Fischer V.
Fitzpatrick R. S.
Flanagan W.
Fleming B.
Fogarty S.
Foreman W.
Forero D. Vanegas
Forero J. F. Castaño
Fowler J.
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Freeman J.
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Friedland A.
Fuess S.
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Furman K.
Furmanski A. P.
Gabrielli A.
Gago A.
Gallagher H.
Gallas A.
Gallice N.
Galymov V.
Gamberini E.
Gamble T.
Ganacim F.
Gandhi R.
Ganguly S.
Gao F.
Gao S.
Garcia-Gamez D.
García-Peris M. Á.
Gardiner S.
Gastler D.
Gauch A.
Gauvreau J.
Gauzzi P.
Ge G.
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Gibin D.
Gil-Botella I.
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Goodwin O.
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Goudeau J.
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Granger P.
Grant C.
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Greenberg S.
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Hahn A.
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Hamilton P.
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Hancock J.
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Hayes C.
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Ji X.
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Jipa A.
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Johnson W.
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Judah M.
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Kaboth A.
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Kakorin I.
Kalitkina A.
Kalra D.
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Karagiorgi G.
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Karcher A.
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Wyenberg J.
Xiao Y.
Xiotidis I.
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Yankelevich A.
Yershov N.
Yonehara K.
Yoon Y. S.
Young T.
Yu B.
Yu H.
Yu H.
Yu J.
Yu Y.
Yuan W.
Zaki R.
Zalesak J.
Zambelli L.
Zamorano B.
Zani A.
Zazueta L.
Zeller G. P.
Zennamo J.
Zetina L. M. Montaño
Zeug K.
Zhang C.
Zhang S.
Zhang Y.
Zhao M.
Zhivun E.
Zimmerman E. D.
Zucchelli S.
Zuklin J.
Zutshi V.
Zwaska R.
Publication venue: 'American Physical Society (APS)'
Publication date: 01/01/2023
Field of study

A primary goal of the upcoming Deep Underground Neutrino Experiment (DUNE) is to measure the

\mathcal{O}(10)

MeV neutrinos produced by a Galactic core-collapse supernova if one should occur during the lifetime of the experiment. The liquid-argon-based detectors planned for DUNE are expected to be uniquely sensitive to the

\nu_e

component of the supernova flux, enabling a wide variety of physics and astrophysics measurements. A key requirement for a correct interpretation of these measurements is a good understanding of the energy-dependent total cross section

\sigma(E_\nu)

for charged-current

\nu_e

absorption on argon. In the context of a simulated extraction of supernova

\nu_e

spectral parameters from a toy analysis, we investigate the impact of

\sigma(E_\nu)

modeling uncertainties on DUNE's supernova neutrino physics sensitivity for the first time. We find that the currently large theoretical uncertainties on

\sigma(E_\nu)

must be substantially reduced before the

\nu_e

flux parameters can be extracted reliably: in the absence of external constraints, a measurement of the integrated neutrino luminosity with less than 10\% bias with DUNE requires

\sigma(E_\nu)

to be known to about 5%. The neutrino spectral shape parameters can be known to better than 10% for a 20% uncertainty on the cross-section scale, although they will be sensitive to uncertainties on the shape of

\sigma(E_\nu)

. A direct measurement of low-energy

\nu_e

-argon scattering would be invaluable for improving the theoretical precision to the needed level.Comment: 25 pages, 21 figure

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Walsh Tim
Walsham James
Ward Kathryn
Warnock Majella
Waterson Sharon
Watkins Claire
Watpool Irene
Watters Malcolm
Waugh Victoria
Webb Steve
Webb Steven A
Wedd Steve
Weismann Dirk
Weissman Alexandra
Wells Colin
Welters Ingeborg
Wetherill Bill
Whelan Ruth
Whileman Amanda
Whitbread Jennifer
White Hayden
White Ian
White Katie
Whitehead Christina
Wibrow Bradley
Wigbers J
Wilby Elizabeth
Wild Laura
Wild Laura
Wilding Laura
Wiley Daisy
Wilhelmsen Elva
Wilkinson Dean
Willams Felicity
Williams Alexandra
Williams Erin
Williams Hannah
Williams Karen
Williams Patricia
Williams Patricia
Williams Penny
Williams Tony
Williams Virginie
Williamson Dawn
Williamson James
Wilson Karen
Wilson Maggie
Wiseman Sophie
Wong Helen
Wood Erica
Wood Hannah
Wood Tracy
Woods Jane
Woods Lindsey
Worner Ruth
Wren Jess
Wren Lynn
Wrey Brown Caroline
Writing Committee for the REMAP-CAP Investigators
Xavier Kugan
Xia Le Tai Charlotte
Yarad Elizabeth
Yates David
Young Chelsea
Young Ian
Young Meredith
Young Paul
Yusuff Hakeem
Zaharia Miahela Florentina
Zaidi Abbas
Zaki Ahmed
Zaman Mohsin
Zammit Claire
Zapalac Marija
Zarychanski Ryan
Zarychanski Ryan
Zhao Xiao Bei
Zinzoni Vanessa
Zitter Letizia
Đimoti Renata
Publication venue: JAMA: Journal of the American Medical Association
Publication date: 06/10/2020
Field of study

Importance: Evidence regarding corticosteroid use for severe coronavirus disease 2019 (COVID-19) is limited. Objective: To determine whether hydrocortisone improves outcome for patients with severe COVID-19. Design, Setting, and Participants: An ongoing adaptive platform trial testing multiple interventions within multiple therapeutic domains, for example, antiviral agents, corticosteroids, or immunoglobulin. Between March 9 and June 17, 2020, 614 adult patients with suspected or confirmed COVID-19 were enrolled and randomized within at least 1 domain following admission to an intensive care unit (ICU) for respiratory or cardiovascular organ support at 121 sites in 8 countries. Of these, 403 were randomized to open-label interventions within the corticosteroid domain. The domain was halted after results from another trial were released. Follow-up ended August 12, 2020. Interventions: The corticosteroid domain randomized participants to a fixed 7-day course of intravenous hydrocortisone (50 mg or 100 mg every 6 hours) (n = 143), a shock-dependent course (50 mg every 6 hours when shock was clinically evident) (n = 152), or no hydrocortisone (n = 108). Main Outcomes and Measures: The primary end point was organ support-free days (days alive and free of ICU-based respiratory or cardiovascular support) within 21 days, where patients who died were assigned -1 day. The primary analysis was a bayesian cumulative logistic model that included all patients enrolled with severe COVID-19, adjusting for age, sex, site, region, time, assignment to interventions within other domains, and domain and intervention eligibility. Superiority was defined as the posterior probability of an odds ratio greater than 1 (threshold for trial conclusion of superiority >99%). Results: After excluding 19 participants who withdrew consent, there were 384 patients (mean age, 60 years; 29% female) randomized to the fixed-dose (n = 137), shock-dependent (n = 146), and no (n = 101) hydrocortisone groups; 379 (99%) completed the study and were included in the analysis. The mean age for the 3 groups ranged between 59.5 and 60.4 years; most patients were male (range, 70.6%-71.5%); mean body mass index ranged between 29.7 and 30.9; and patients receiving mechanical ventilation ranged between 50.0% and 63.5%. For the fixed-dose, shock-dependent, and no hydrocortisone groups, respectively, the median organ support-free days were 0 (IQR, -1 to 15), 0 (IQR, -1 to 13), and 0 (-1 to 11) days (composed of 30%, 26%, and 33% mortality rates and 11.5, 9.5, and 6 median organ support-free days among survivors). The median adjusted odds ratio and bayesian probability of superiority were 1.43 (95% credible interval, 0.91-2.27) and 93% for fixed-dose hydrocortisone, respectively, and were 1.22 (95% credible interval, 0.76-1.94) and 80% for shock-dependent hydrocortisone compared with no hydrocortisone. Serious adverse events were reported in 4 (3%), 5 (3%), and 1 (1%) patients in the fixed-dose, shock-dependent, and no hydrocortisone groups, respectively. Conclusions and Relevance: Among patients with severe COVID-19, treatment with a 7-day fixed-dose course of hydrocortisone or shock-dependent dosing of hydrocortisone, compared with no hydrocortisone, resulted in 93% and 80% probabilities of superiority with regard to the odds of improvement in organ support-free days within 21 days. However, the trial was stopped early and no treatment strategy met prespecified criteria for statistical superiority, precluding definitive conclusions. Trial Registration: ClinicalTrials.gov Identifier: NCT02735707

Apollo (Cambridge)

Highly-parallelized simulation of a pixelated LArTPC on a GPU

Author: Abed Abud A.
Abi B.
Acciarri R.
Acero M.A.
Adames M.R.
Adamov G.
Adamowski M.
Adams D.
Adinolfi M.
Adriano C.
Aduszkiewicz A.
Aguilar J.
Ahmad Z.
Ahmed J.
Aimard B.
Akbar F.
Allison K.
Alonso Monsalve S.
Alrashed M.
Alt C.
Alton A.
Alvarez R.
Amedo P.
Anderson J.
Andrade D.A.
Andreopoulos C.
Andreotti M.
Andrews M.P.
Andrianala F.
Andringa S.
Anfimov N.
Anicézio Campanelli W.L.
Ankowski A.
Antoniassi M.
Antonova M.
Antoshkin A.
Antusch S.
Aranda-Fernandez A.
Arellano L.
Arnold L.O.
Arroyave M.A.
Asaadi J.
Ashkenazi A.
Asquith L.
Aurisano A.
Aushev V.
Autiero D.
Ayala-Torres M.
Azfar F.
Back A.
Back H.
Back J.J.
Bagaturia I.
Bagby L.
Balashov N.
Balasubramanian S.
Baldi P.
Baldini W.
Baller B.
Bambah B.
Barao F.
Barenboim G.
Barham Alzás P.
Barker G.J.
Barkhouse W.
Barnes C.
Barr G.
Barranco Monarca J.
Barros A.
Barros N.
Barrow J.L.
Basharina-Freshville A.
Bashyal A.
Basque V.
Batchelor C.
Battat J.B.R.
Battisti F.
Bay F.
Bazetto M.C.Q.
Bazo Alba J.L.L.
Beacom J.F.
Bechetoille E.
Behera B.
Belchior E.
Bellantoni L.
Bellettini G.
Bellini V.
Beltramello O.
Benekos N.
Benitez Montiel C.
Benjamin D.
Bento Neves F.
Berger J.
Berkman S.
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Berner R.M.
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Bilki B.
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Bitadze A.
Blake A.
Blaszczyk F.D.
Blazey G.C.
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Zutshi V.
Zwaska R.
Publication venue: 'IOP Publishing'
Publication date: 01/01/2023
Field of study

The rapid development of general-purpose computing on graphics processing units (GPGPU) is allowing the implementation of highly-parallelized Monte Carlo simulation chains for particle physics experiments. This technique is particularly suitable for the simulation of a pixelated charge readout for time projection chambers, given the large number of channels that this technology employs. Here we present the first implementation of a full microphysical simulator of a liquid argon time projection chamber (LArTPC) equipped with light readout and pixelated charge readout, developed for the DUNE Near Detector. The software is implemented with an end-to-end set of GPU-optimized algorithms. The algorithms have been written in Python and translated into CUDA kernels using Numba, a just-in-time compiler for a subset of Python and NumPy instructions. The GPU implementation achieves a speed up of four orders of magnitude compared with the equivalent CPU version. The simulation of the current induced on 10^3 pixels takes around 1 ms on the GPU, compared with approximately 10 s on the CPU. The results of the simulation are compared against data from a pixel-readout LArTPC prototype

University of Liverpool Repository

Archivio istituzionale della Ricerca - Università degli Studi di Parma

Archivio istituzionale della ricerca - Università di Ferrara

Queen Mary Research Online

White Rose Research Online

Archivio Istituzionale della Ricerca- Università del Salento

Archivio istituzionale della ricerca - Università di Padova

Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19

Author: ?ivko Iris
Abbass Hakam
Abdeladim Lilia
Abdelhady Hesham
Abdelkharim Hussam
Abdelrazik Marwa
Abdi Zakee
Abdukahil Sheryl Ann
Abel Lynn
Abraham Jacinta
Abrahamson Gail
Abusamra Yousuf
Aceto Romina
Adams Nick
Adams Peter
Adebambo Olumide
Adhikari Neill
Adhikari Sheetal
Affleck Julia
Agha Gloria
Aghemo Alessio
Agno Ronan
Ahmad Norfaizan
Ain Quratul
Ainscough Kate
Ainsworth James
Aitken Lindianne
Akamp Ceren
Al Enezi Farhan
Al-Bassam Wisam
Al-Beidh Farah
Albert Martin
Albrett Jonathan
Alderman Meera
Aldo Bonizzoni Matteo
Alegria Ana
Alessandro Carà Gianmarco
Alexander Brian
Alexander Peter
Alfonso Jordan
Ali Maryam
Ali Murtaza
Allam Hayat
Allen Barbara
Allen Louise
Allibone Suzanne
Almeshhedani Hasham
AlQahtani Samah
Alswaidan Lolowa
Altomy Mohammed
Al Amri Ali
Al Qasim Eman
Amatya Sameena
Ambrosino Richard
Anderson Thomas
Andreae Mark
Aneman Anders
Angus Derek C.
Anjum Aisha
Ankert Juliane
Annane Djillali
Anne-Laure Fedou
Anstey Matthew
Antcliffe David
Anthony Alpha
Antoine Marchalot
Antoine Pierre
Antoine Studer
Anumakonda Vikram
Aparicio Christelle
Aquino Maia
Arabi Yaseen M.
Arachchige Malka
Aravindan Latha
Arbane Gill
Archambault Patrick
Archer Simon
Aref Noah
Arias Ana-Marie
Arias Sonia
Arishi Hatim
Arnold Donald
Arnold John
Arnott Andrew
Arora Anand
Aryal Diptesh
Asghar Adeeba
Asif Namra
Aspinwall Angelique
Attokaran Antony
Attwood Ben
Au Carly
Audry Mathilde
Austin Karen
Austin Pauline
Auvet Adrien
Avard Bronwyn
Awan Sidra
Ayee Robert
Azaiz Amine
Azzaui Harun
Babu Suresh
Bacon Gina
Badalamenti Salvatore
Badie Julio
Bagavathy Kavitha
Bagot Catherine
Bagshaw Sean
Baig Nadia
Baikady Ravishankar
Bailey Lucy
Baillie Kenneth
Bain William
Baker Alice
Baker Evelyn
Baker Stuart
Bakthavatsalam Dhanalakshmi
Balaie Morteza
Balls-Burgess Sam
Bamford Amy
Bamford Peter
Banach Dorota
Bannard-Smith Jonathan
Barbash Ian
Barber Russell
Barbier François
Barge Deborah
Bariola Ryan
Barker Gareth
Barker Stephanie
Barnes Nicky
Baron Rebecca M.
Barreau Amelie
Barreau Amélie
Bart Robert
Bartholomew Jazz
Bartley Shauna
Barton David
Barton Frances
Bashyal Archana
Basile Kim
Bass Frances
Bassford Christopher
Bastos Joana Margarida Pereira Sousa
Bates Michelle
Bates Samantha
Batista Teresa Margarida Oliveira
Bauchmuller Kris
Bayne Madeleine
Bean Sarah
Beane Abi
Beane Abigail
Beard Gregory
Beasley Richard
Beaudoin Rosalie
Beavis Sarah
Beddows Seonaid
Bedford Caroline
Beer Deborah
Beer Sally
Begin Phillipe
Begum Salma
Bell Gillian
Bellemare David
Belletti Allesandro
Bendjemar Lynda
Benettaib Fatna
Bensen Nicole
Bentley Andrew
Benyon Sarah
Benzekri Dalila
Beqai Besa
Berdaguer Fernando
Beresford Stephanie
Bergin Colin
Berry Lindsay R.
Berry Scott
Berryman Emily
Bertel Melanie
Best-Lane Janis
Besten Henny
Bevan Emily
Bewley Jeremy
Beyerl Ashley
Bhagani Sanjay
Bhandal Khushpreet
Bharaj Kiranjit
Bhattarai Bina
Bhattarai Binita
Bhonagiri Deepak
Biddie Simon
Bigas Judit
Bihari Shailesh
Bin Hasan Mohd Shahnaz
Bindels Manon
Binnie Alexandra
Biradar Vishwanath
Birch Catherine
Birch Janine
Birch Sophie
Birchall Kathrine
Birkinshaw Isobel
Black Ethel
Blackledge Bethany
Blakemore Hayley
Blanck Wendy
Bland Yvonne
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Bleasdale John
Bloomfield Jack
Bloos Frank
Board Jasmin
Boardman Melanie
Boari Gianluca
Bocher Simon
Bociek Aneta
Boivin Anne-Helene
Boivin Anne-Hélène
Bojunga Jörg
Bomken Charlotte
Bonaccorso Allesandra
Bongaerts Katherine
Bonner Stephen
Bonten Marc J. M.
Borgatta Barbara
Borislavova Borislava
Borrill Zoe
Boschert Catherine
Bossard Isabelle
Bothma Pieter
Boudineau Michel
Boulanger Marie-Claude
Boumahni Dounia
Bouman Angela
Bounab Rania
Bourgoin Charlotte
Bourne Michelle
Bourne Richard
Boutin Mireille
Bouvier Elodie
Bouw-Ruiter Marianne
Boué Yvonnick
Bowen James
Bowler Helen
Boyd Craig
Boyles Rebecca
Bracke Stephanie
Bradbury Charlotte A.
Bradley Paul
Brady Kara
Brailsford Jane
Brain Matthew
Brakké Karen
Brant Emily
Brasselet Aurélie
Breen Patrick
Bremmer Pamela
Brend Morwenna
Brennan Aoife
Bretagnol Anne
Brett Stephen
Brewer Chris
Brickell Kathy
Bridges Sarah
Brieger Klaus-Gerd
Brightling Chris
Brimfield Lutece
Brittain Michael
Britton Kate
Brochard Laurent
Brodbeck Andreas
Brohi Farooq
Brooks Nicole
Brown Cynthia
Brown Julia
Brown Louise
Brown Nerissa
Brown Zarah
Brugman Curt
Brunetta Enrico
Brunkhorst Frank M.
Brunskill Nigel
Bryan-Morris Kayla
Bryden Emma
Budd Joanna
Buehner Ulrike
Buhay Megan
Buhr Heidi
Burbee Dylan
Burda Dorota
Burgess Richard
Burke David
Burke Tara
Burkey Jason
Burnish Rachel
Burns Dean
Burns Karen
Burrell Aidan
Burt Karen
Buscher Hergen
Butler Amelia
Butler Magdalena
Butler Susan
Buxton Meredith
Buzgau Adrian
Byrne Kathleen
Byrne Rahim
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Cabreros Leilani
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Calfee Carolyn
Callahan Jean-Christophe
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Campbell Andrew
Campbell Bridget
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Campbell Hilary
Campbell Lewis
Campbell Marion
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Campion Alexandra
Campisi Josie
Camsooksai Julie
Caplin Cecile
Carbonneau Elaine
Carmichael Samantha
Carmona Rosario
Carn Vanessa
Carpio Lillian
Carr Zoe
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Carrier François
Carrier Marc
Carter Angus
Carter Brittney
Carter David
Carter Jay
Carter Michael
Casali Sherry
Casey Ruth
Casey Siobhan
Castelain Vincent
Castle James
Cathcart Susanne
Catorze Nuno José Teodoro Amaro dos Santos
Cattelan Jessy
Cavayas Alexandros
Cawley Kathryn
Cecconi Maurizio
Centofanti John
Chambers Emma
Champanerkar Shreekant
Chan Carmen
Chan Charles
Chan Peter
Chapman Rachel
Chapman Susan
Charles Bethan
Charles Walton
Charlewood Richard
Charlton Sam
Charron Cyril
Chartier Delphine
Chasse Michael
Chassé Michaël
Chen Jonathan
Chen Lixian
Chen Yan
Cheng Allen C.
Cherian Shiney
Chhablani Manish
Chin Teri
Chudeau Nicolas
Chukkambotla Sri
Ciccarelli Michele
Cirstea Emanuel
Clair Bernard
Clark Amy
Clark Michele
Clark Richard
Clark Sarah
Clarke Frances
Clarke Jennifer
Claxton Andrew
Cleary Joanne
Clement Ian
Clere-Jehl Raphael
Clermont Giles
Clermont Gilles
Clinton Alison
Cloutier Ève
Cockrell Maeve
Codreanu Daniel
Coetzee Samantha
Coghlan Phoebe
Cole Jade
Coles Jennifer
Colin Gwenhael
Collier Dawn
Collins Amy
Collins Daniel
Collins Emma
Collins Joanne
Collins Érin
Collis Matthew
Combaux Daniele
Commons Robert
Comp Susan
Concha Pablo
Connolly Karen
Constantini Elena
Constantino-Occhipinti Claudia
Contou Damien
Convery Karen
Conway Robert
Conzelmann Nadine
Cook Deborah
Cook Tim
Cooke Jill
Cooke Justin
Cooper Jamie
Cooper Josh
Cooper Lauren
Cooper Melanie
Cooper Nichola
Corbett Sarah
Corcoran Ele
Corcoran Kathleen
Cornell Sarah
Cornell Thomas
Cort Jon
Costerousse Olivier
Couillard-Chénard Émilie
Courtin Laura
Coutts Amanda
Couture Lourie
Cove Matthew
Cowdrey Keri-Anne
Cowley Nicholas
Cowton Amanda
Coyne Mark
Craddock Richard
Craner Michelle
Craven Thomas
Crawshaw Sarah
Creagh-Brown Ben
Creange Vanessa
Cremer Olaf
Crisp Nikki
Croft Maria
Csabi Peter
Cudlipp Joanna
Cuesta Jeronimo
Cuffaro Raffaele
Curley Gerard
Currie Andrew
Cusack Rebecca
Cuthbertson Brian
Cutler Sean
Cárcel Sheila
Côté Émilie
D?Amato Fabiola
D?Aragon Frédérick
Daebis Admad
Daher Rana
Dale Katie
Daley Jessica
Dalton James
Daly James
Daly Zoe
Daneman Nick
Dark Paul
Darnell Robert
Darreau Cedric
Daugherty Jason
Davey Miriam
Davidson Neil
Davies Ellie
Davies Gwyneth
Davies Jennifer
Davies Louisa
Davies Michelle
Davies Rhys
Dawson Laura Ann
Dawvda Ashlish
Day Christopher
Da Rocha Joana
De Bus Liesbet
de Courcy-Golder Kim
de Groot Klaas
de Jong Menno
de Jonge Evert
De Keulenaer Bart
de la Torre Cisneros Julian
de Man Angelique
De Neef Mark
De Smeytere Anouska
Deacon Bethan
Dean Steven
Dean Tessa
Dearden Joy
Dechert William
Declercq Pierre-Louis
Degracia Anna
del Sorbo Lorenzo
Dela Rosa Arnold
Delaney Kirsha
Dell Abbie
del Prado Michael
Demetriou Carrie
Dempster Debra
Denham Lynn
Denmade Craig
Dent Martin
Depante Maria
Depuydt Pieter
Dequin Pierre-François
Derde Lennie P. G.
Deshpande Kush
Detry Michelle A.
Deye Nicolas
de la Fuente Carmen
De Waele Jan
Dheke Krishan
Di Lucca Giuseppe
Dias Priya
Dice Julie
Digby Stephen
Diridis Kristina
Distler Michael
Dobell-Brown Kelsey
Doble Patricia
Dobson Jade
Doherty Kaleigh
Doherty Ronan
Doi Yohei
Dolman Rozzie
Domingo-Marco Joana
Donadee Chenell
Donaldson Kate
Dondrop Arjen
Donegan Clare
Donlon Sinead
Donnelly Adrian
Donnelly Kieran
Donnison Phil
Doonan Reece
Doran Peter
Dore Rachael
Dormand Natalie
Dos Santos Filipa
Douillard Thomas
Drake Chelsea
Drapola Debra
Drayss Maria
Drummond Andrew
Drury Kay
Duan Erick
Duberley Stephen
Duffy Eamon
Duffy Oscar
Duke Graeme
Duke Zoe
Duncan Tracy
Dunsavage Janice
Duplaix Mathilde
Duric Natalie
Duroux Maree
Dushianthan Ahilanandan
Dyas Sarah
Eapen Beena
Eastgate Christine
Ebenezer R
Edmunds Natasha
Edwards Alexandra
Efford Georgia
Egreteau Pierre
Ehrmann Stephan
Eichenauer Dennis
Eisenbeis Simone
Ekhérian Jean-Michel
El-Khawas Khaled
Elender Corinna
Elgendy Ahmad
Elhassan Munzir
Ellervee Anneli
Ellis Chiara
Ellis Christine
Ellis Yvette
Elmahi Einas
Elsefi Tarek
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Elvira Evangeline
England Jenna
Englert Sarah
English Shane
Epelman¸ Slava
Eroglu Ege
Estcourt Lise J.
Estensen Kristen
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Everitt Robert
Evers Mirjam
Evetts George
Ewalds Esther
Ezekowitz Justin
Fagan Laura
Fagbodun Elizabeth
Farahi Neda
Fareed Komal
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Fartoukh Muriel
Faulkner Beverley
Faulkner Maria
Fazla Fathima
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Felton Tim
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Ferguson Niall
Ferguson Susan
Fergusson Dean
Fernandes Edna
Fernandez Maria
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Fernández de Pinedo Artaraz Ziortza
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Ferrier Janet
Ferringer Cindy
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Finn André
Finn Stephanie
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Flint Neil
Flor Thomas
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Focà Emanuele
Folci Marco
Forbes Andrew
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Foulds Angela
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Fowler Robert
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Fox Eleonore
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Godement Mathieu
Godoy Lucas C.
Goebeler M.E.
Golden David
Goldman John
Goligher Ewan
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Gommans Frank
Goodwin Jayne
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Halden Sandra
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Hall Amelia
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Harper Heather
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Harris John
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Harrison Susan
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Haydon Tim
Hayes Amber
Hayes Anne
Hayes Kati
Hayes Leanne
HC Ooi
Headdon William
Headlam Evie
Healey Gail
Hegazy Ahmed
Hegazy Mohamed
Heinonen Jonna
Helms Julie
Heming Nicholas
Henderson Kelly
Henderson Steven
Henning Jeremy
Henri-Lagarrigue Matthieu
Henry Joanne
Henry Lavinia
Hensley Joseph
Heritier Stephane
Hernandez Erik
Hewitt Claire
Hey Samuel
Hickey John
Hierons Sarah
Higgins Alisa M.
Hill Claire
Hill Dianne
Hill Helen
Hilldrith Anette
Hills Thomas
Hin Lui Lok
Hindle Grace
Hinrichs Carl
Hird Clare
Hodge Christopher
Hodgson Carol
Hodgson Helen
Hoff Uwe
Hoiting Oscar
Holbrook Catherine
Holland Andrew
Holland Nicky
Holland Susan
Hollos Laszlo
Homes Jennifer
Honda Hitoshi
Hope David
Hopkins Phil
Hormis Anil
Horner Dan
Hornsby James
Horton Michelle
Horvat Christopher M.
Howcroft Clare
Howell Alice
Hower Martin
Howie Lucy
Howle Ryan
Hoxha Elvira
Huang David T.
Hughes Debbie
Hugill Keith
Huijbens Danique
Hullegie Sebastiaan
Hulley Amanda
Hulme Jonathan
Hulse Sarah
Humphrey Charlotte
Hunt Beverley
Hunter Stephanie
Hurford Sally-Anne
Hussain Mahwish
Hussain Sajid
Hutchinson Christina
Hutton Paula
Hüning Vanessa
Ichihara Nao
Ijaz Nazia
Ikhena Ikhuemose
Inskip Deborah
Irving Ben
Isgro Graziella
Isguzar Agah
Ishani Pramodya
Ivatt Helen
Jackson Carolyn
Jackson Shane
Jackson Susan
Jacob Reni
Jacquier Sophie
Jafarzadeh Mina
Jagannathan Vijay
Jain Susan
James Augustian
James Christie
Jan Hassing Robert
Janin Pierre
Jarczak Dominik
Jarman Claire
Jayakumar Deva
Jayakumar Devachandran
Jean-Pierre Eraldi
Jeblaoui Asma
Jenkins Samuel
Jenkins Sarah
Jenkins Steve
Jennings Stacey
Jepson Eleanor
Jerenec Katja
Jesty Robert
Jha Avinash
Jha Rajeev
Jhanji Shaman
Jin Xia
Jindai Kazuaki
John Maya
Johns Magaret
Johnson David
Johnson Paul
Johnson Rebekah
Johnson Toby
Johnston Brian
Jones Andrea
Jones Cathy
Jones Dawn
Jones Emily
Jones Jessica
Jones Samantha
Jongebloed Katherine
Joseph Sibet
Joseph Treesa
Joyce Kirsten
Juffermans Nicole
Juhaz Vera
Kadam Umesh
Kalamar ?iga
Kalchko-Veyssal Selver
Kalchthaler Kyle
Kaliappan Agilan
Kalla Ismail
Kalogirou Michael
Kamata Kazuhiro
Kamel Toufik
Kampschreur Linda
Kamra Maneesha
Kandeepan Revathi
Kannan Santhana
Kannan Thogulava
Kanwal Darakhshan
Karachi Tim
Karim Hina
Karki Rakshya
Karlikowski Michal
Karlsson Sari
Kasipandian Vidya
Kassir Sandy
Katary Amro
Kato Hideaki
Kavanagh Lisa
Kayani Abdul
Kayastha Srijana
Kaye Callum
Kazi Aayesha
KC Shirish
KC Shirsh
Keating Liza
Keatley Claire
Keeler Sheryl
Keen Alexandra
Keen Sherbrina
Keijzer-Timmers Nicole
Kell Kay
Kelly Martin
Kelly Niamh
Kelsall Olivia
Kendrick Sara
Kernan Maeve
Kerslake Ian
Kester Esmee
Khade Reena
Khalid Imrana
Khan Meherunnisa
Khanal Kishor
Khanal Sushil
Khare Divya
Khoso Nasir
Khoud Ahmed
Khwaja Kosar
Kidwai Aneela
Kiiski Heikki
Kilner Mari
Kim Edy Y.
Kimpton Sarah
King Andrew
Kinney Fiona
Kirk Jill
Kirk Rosemary
Kirkby Amy
Kirkham Simon
Kit Barbara
Kitsios Georgios
Kittridge Lauren
Klein Daniela
Klop-Riehl Margreet
Kluge Stefan
Knowles Karen
Kochanek Matthias
Kochert Erik
Koelink Maaike
Koirala Kanchan
Koirala Sabin
Kolanos Steffi
Kolovou Angeliki
Konecny Pam
Kong Jing
Koopmans Matty
Kosa Alma
Kremling Julius
Kreß Gabriele
Krishnamoorthy S
Krishnamurthy Vinodh
Kruger Peter
Kruisdijk-Gerritsen Arriette
Kruisselbrink Rebecca
Kuitunen Anne
Kumar Anand
Kumar Nikhil
Kumar Rohit
Kummerlen Christine
Kunishima Hiroyuki
Kunwar Puja
Kunz Kevin
Kurenda Catherine
Kutsogiannis Demetrios
Kuybida Yuriy
Kwan Yvonne
Kyeremeh Lynsey
Kyle Laura
L?Hotellier Sylvie
Labbe Vincent
Laffan Mike
Laffey John
Laha Shondipon
Lai Vivian
Lambert Bridget
Lamontagne Francois
Lampro Lamprini
Landais Michaël
Landoni Giovanni
Landsiedel-Mechenbier Elke
Lang Eva
Langridge Emma
Latham Victoria
Latino Reece
Laudi Svenja
Laugs Fabian
Lavana Jayshree
Laver Russell D.
Law Daniel
Lawler Patrick R.
Le Basnier Elliot
Le Guen Lenaïg
Le Loup Guillaume
Leaf David E.
Lean Richard
Leaver Susannah
Leavis Helen
Leblond Julie
Leditschke Anne
Lee Kelvin
Lee Stephanie
Lee Stephen
Lefevre Montaine
Leffelaar Evelien
Lehalleur Adrien
Lellouche Francois
Lemaire-Brunel Delphine
Lembo Rosalba
Leparco Cécile
Leroyer Marie-Helene
Lesona Eden
Levett Chris
Lewis Joanne
Lewis Roger J.
Lewis Sarah
LewisProsser Lorraine
Liao Angela
Lim Rosario
Limb James
Lindergard Gabriella
Linnett Vanessa
Linstrum Kelsey M.
Litton Ed
Litton Edward
Liu Theresa
Lizotte Patricia
Lock Stephen
Lockett Teresa
Logan Meg
Lomme Kaatje
Long Matilda
Lopus Alyssa
Lorenzi Elizabeth
Lother Sylvain
Lowe Benjamin
Lowery Maryalyce
Lowrey Julie
Lucas Rachael
Luis David
Luitel Subekshya
Luk Tracy
Lunde Ragnar
Luo Ji
Lye Alison
Lynch Ceri
Lynch Daniella
López Maria
López Rafael
Löbel Madlen
MacKay Callum
Mackay Euan
Mackay Josephine
MacKay Lynn
Mackenzie Brittney
Mackintosh Katherine
MacLennan Sheila
MacTavish Pamela
Madani Yasser
Madarbukus Daanyaal
Maharajh Amitaa
Maharjan Mili
Maharjan Radhika
Maharjan Sabi
Maiden Matthew
Mailman Jonathan
Major Emmet
Makanju Esther
Makky Ahmed
Makowski Arystarch
Malakouti Salim
Male Michelle
Malfroy Sylvain
Mali Sharmila
Malissin Isabelle
Malley Brian
Maloney Carolyn
Maloney Gracie
Mandadapu Vineela
Mani Ashwin
Manley Rachel
Manoharan Venika
Maquigneau Natacha
Marchesi Mattia
Mariappa Vasanth
Marin-Corral Judith
Marin?ek Martin
Marinoff Nicole
Marion Beuzelin
Markota Andrej
Marmol Joy
Marnai Remy
Marriot Cheryl
Marriott Yvonne
Marroquin Oscar
Marsden Tracy
Marsh Emma
Marshall John C.
Marshall Lucy
Marten Nicole
Martin Elise
Martin Emma
Martin Jane
Martin Laila
Martin Timothy
Martin-Lazarro Juan
Martinez Maria
Martucci Antonio
Martynoga Robert
Mary-Genetu Roman
Mascherpa Glenda
Masdeu-Eixarch Gaspar
Maselli Astrid
Mason Alexina
Mason Brittany
Masood Sobia
Massar Brent
Masse Marie-Helene
Massey Natalie
Masters Kristy
Mataliotakis Michail
Mathew Meghena
Mathew Moncy
Mathonnet Armelle
Matimba-Mupaya Wadzanai
Matsa Ramprasad
Matthews Julie
Maxime Virginie
Mayak Katelyn
Mayangao Irving
Maynard Victoria
Mayr Florian
Mc-Kenzie Josette
McAdams David
McArthur Colin J.
McAuley Daniel F.
McAuley Julie
McCallion Edmund
McCarthy Aine
McClintock Declan
McConnochie Rachael
McCracken Phoebe
McCreary Erin
McCreath Gordan
McCullagh Iain
McCullagh Liz
McCulloch Corrienne
McCullough James
McDonald Bree
McDyer John
McEldrew Ben
McEldrew Rebecca
McEvoy Natalie
McGain Forbes
McGarry Karen
McGhee Christopher
McGlothlin Anna
McGloughlin Steve
McGlynn Deborah
McGoldrick Clare
McGuigan Peter
McGuinness Shay P.
McIntyre Joanne
McIntyre Lauralyn
McKee Madeleine
McKenna Shirley
McKenna Sonia
Mckeon Laurie
Mclaughlan Danielle
McMaster Moyra
McMillan Alexandra
McMillan Catherine
McMillan Helen
McMorrow Liam
McNamara Amanda
McNamara Robert
McNicholas Bairbre
McQuilten Zoe
McVerry Bryan J.
McWilliam Stephen
Medhurst Laura
Medva Rebecca
Meermeier Werner
Megarbane Bruno
Mehrtens Jan
Mehta Reena
Meijer Karina
Menon David
Mercier Emmanuelle
Mercier Romain
Merdji Hamid
Meredith Megan
Metherell Stella
Meunier Juliette
Mevavala Bhaumik
Mew Louise
Meyer Jason
Mezher Chaouki
Meziani Ferhat
Mfuko Celina
Mguni Nhlanhla
Michael Angiy
Michalak-Glinska Natalia
Middledorp Saskia
Miezitis Sydney
Mikusek Justyna
Mila de la Fuente Gema
Miles Helen
Millen Tina
Miller Amanda
Miller Jennene
Miller Lorna
Mills Gary
Miln Rebecca
Minnier Tami
Mistry Deena
Misztal Beata
Mitchard Sarah
Moakes Emma
Moghbeli Kaveh
Mohammed Amal
Moine Pierre
Mokhtar Nabih
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Monaghan Maree
Monchi Mehran
Moneger Guy
Monnier Alexandra
Monzon Angelica
Moore Lorraine
Moore Vanessa
Moorhouse Louise
Morel Guillaume
Morgan Karen
Morgan Matt
Morgan Stacey
Morpeth Susan
Morris Anna
Morris Jenny
Morris Lucy
Morris Sheila
Morrison Lynette
Mouncey Paul R.
Mowery Brent
Mrad Aymen
Mtuwa Shelia
Mukherjee Dipak
Mulder John
Mulier Jelle
Mulla Suleman
Mullan Dee
Muller Grégoire
Munt Sheila
Murphy Aisling
Murphy Lorna
Murphy Peter
Murphy Ryan
Murphy Sheenagh
Murray Andrew
Murray Lauren
Murray Lyle
Murthy Srinivas
Music Edvin
Muteithia Margaret
Muvindi Himasha
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Muñoz-Bermúdez Rosana
Mwaura Esther
Mwembani Tina
Naeem Anas
Naidu Brintha
Naim Giulia
Nair Priya
Nakamuro Hiromi
Nakazono Kenichi
Nakhnoukh Cristina
Nand Kiran
Nandani Aarti
Navarra Leanlove
Nay Mai-Anh
Nayyar Vineet
Naz Mobeena
Neal Matthew
Nee Jens
Neill Andy
Nelli Apoorva
Nemeth Christopher
Nemeth-Roszpopa Karolina
Netea Mihai
Netherton Kimberley
Neto Ary
Newbould David
Newlands Jessica
Newman Julie
Newman Tabitha
Ng Anthony
NG Christopher
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Nguyen-Valat Thi-My-Hue
Nichol Alistair D.
Nicholier Tiphaine
Nicholson Andrew
Nicholson Anne
Nicholson Sarah
Nickoleit-Bitzenberger Daniela
Nierhaus Axel
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Noble Harriet
Noel-Hunter Monia
Nolan Jerry
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North Julie
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Nourse Mary
Nown Angie
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O Rourke Kate
O'Connell Martin
O'Kell Eleanor
O'Neill Lorraine
O'Neill Stephen
O'Reilly Joanna
O?Brien Julie
O?Brien Neale
O?Connor Aibhilin
O?Connor Anne
O?Connor Caroline
O?Connor Stephanie
O?Dwyer Michael
O?Halloran Sinead
O?Kane Cecilia
O?Kane Sinéad
O?Leary Ryan
O?Malley Laura
O?Neill Aisling
O?Reilly Kevin
Oakley Susan
Oborska Aneta
Occhipinti Giovanna
Ochin Evelina
Oczkowski Simon
Ogg Bethan
Ogungbenro Kayode
Okubanjo Maryanne
Okundaye Clementina
Oliver Anne
Oliver Martyn
Omer Nimca
Oncea Lynne
Orford Neil
Oritz-Ruiz de Gordoa Laura
Orlikowska Izabela
Orlikowski David
Orr Katrina
Osagie Rawlings
Osborne Alexander
Osborne Jason
Osinga Margreet
Ostermann Marlies
Ottens Thomas
Owen David R. J.
Oza Deepali
Padmakumar Anand
Page Shannon
Page Valerie
Pakats Mari-Liis
Pakou Glykeria
Palermo Annamaria
Paneru Hem
Panjwani Ashok
Panwar Rakshit
Pappa Evita
Paramasivam Elankumaran
Parekh Dhruv
Parikh Harshel G.
Parke Rachael L.
Parker Jane C.
Parker Lorraine
Parker Natasha
Parmar Dinesh
Parry-Billings Karen
Parsons Penny
Pasieka Bastian
Patanwala Asad
Patawala Asad
Patch Sarah
Patel Amit
Patel Bijal
Patel Brijesh
Patel Kamal
Paterson David
Pathak Shreya
Patil Sonal
Patterson Lisa
Paudel Pratibha
Peake Sandra
Pearson Harriet
Pearson Karen
Pech Yadira
Pegler Suzannah
Pellicano Susan
Pemberton Abigail
Pendlebury Jessica
Pereira Rita
Pereira Tiago Nuno Alfaro Lima
Perez Jane
Perri Reno
Peters Anna
Peters Cecilia
Peters Marco
Peters Sam
Peters Svenja
Petros Sirak
Pettilä Leena
Pettilä Ville
Phalod Gunjan
Philbin Jennifer
Philip Annlin
Philippe Rigaud
Phillips Barbara
Phillips Matt
Phua Jason
Phull Mandeep-Kaur
Phuyal Aarti
Pickering Charlotte
Pickkers Peter
Piercy Charlie
Pietersma Mario
Pillai Suresh
Pinder Meredith
Pinnell Jez
Pinto Marta
Pitts Sally
Piva Simone
Plantefeve Gaetan
Platenkamp Ellen
Plesnikova Yvonna
Pletz Mathias
Plummer Bethany
Plummer Mark
Pogreban Tatiana
Pogson David
Polfliet Margot
Polgarova Petra
Polley Grace
Pollock Katrina M.
Pomeroy Fiona
Poojara Latesh
Pooni Jagtar- Singh
Porteous Rebecca
Porter David
Postlethwaite Kelly
Postma Douwe
Potter Alison
Potter Sarah
Poulter Amber-Louise
Poupblanc Séverine
Pouplet Caroline
Pourcine Franck
Povoa Pedro
Powell Elizabeth
Prabakaran Rajalakshmi
Pradel Gael
Pratheema Ramachandran
Prebeg Katharina
Preijers Lieke
Presneill Jeffrey
Pridee Nicole
Prinssen Anton
Pritchard Kelly
Proudfoot Nicola
Prout Rachel
Pugh Richard
Purandare Laura
Purnell Rebecca
Purohit Dharam
Purvis Sarah
Puskarich Michael
Putensen Daniel
Puthucheary Zudin
Puxty Kathryn
Pérez-Terán Purificación
Põldots Liisi
Qiu Shan
Qiu Xinyi
Quayle Rachael
Quenot Jean Pierre
Quinn Alison
Quinn Kevin
Qureshi Hafiz
Raczek James
Rad Laura
Rademaker Emma
Rahmani Hassene
Rai Namrata
Rai Sabi
Raithatha Ajay
Raj Ashok
Ralston Maximillian
Ramakrishnan N
Ramali Mohamed
Ramamurthi Balaji
Ramanan Mahesh
Ramos Angelo
Ramos Lidia
Randell Georgina
Rangan Ritika
Ranganathan Lakshmi
Rao Deepak
Rashan Aasiyah
Rashan Sumayyah
Ratcliffe Megan
Ratnam Valli
Ravry Celine
Rawlins Sam
Reay Michael
Rebello Rashmi
Reddy Amie
Reddy Harsha
Reed Catherine
Rees Stephanie
Reeve Brenda
Regli Adrian
Rehman Atique
Reid Andrew
Reid Liadain
Reidy Bryan
Reill Lorenz
Reinhard Veronika
Rengers Els
Rennit Pille
Reschreiter Henrik
Reverté-Villarroya Silvia
Revill Adam
Rewa Oleksa
Reyes Luis Felipe
Reynolds Bob
Reynolds Claire
Reynolds Jessica
Rhodes Jonathan
Richards Carol
Richards Suzanne
Richards-Belle Alvin
Richardson Aaron
Richardson Angus
Richecoeu Jack
Riches Joanne
Ricketts Dan
Ricketts Daniel
Riddell Phillip
Riepe Ansgar
Rietveld Ilse
Rimmer Dominic
Ripa Marco
Rissen Reimer
Ristimäki Sanna
Ritzema Jenny
Rivett Justine
Rizzoni Damiano
Roberts Belinda
Roberts David
Roberts Eilir
Roberts Tracey
Robertson Debra
Robinson Matt
Roche Lisa
Roche-Campo Ferran
Rochwerg Bram
Rodden Natalie
Rodriguez Marina
Rodríguez-Gómez Jorge
Roebers Harald
Roedl Kevin
Rohde Gernot
Rojo Roceld
Romagnuolo Tina
Roman Jaime
Romberg Birgit
Rook Clare
Rooney Kevin
Roovers Noortje
Rosaroso Lace
Rosborough Brian
Rose Steve
Rosenstein-Sisson Rachel
Ross Elizabeth
Rostron Anthony
Roth Jason
Rouge Patrick
Roumen Rudy
Rounds Charles
Rovere-Querini Patrizia
Rowan Kathryn M.
Rowe-Leete Louise
Rowland Matthew
Roy Alistair
Roynon-Reed Anna
Rueß-Paterno Giusi
Ruiz Winningtom
Runge Isabelle
Ruselli Giovanna
Russo Giada
Ryalls Kim
Ryan Donal
Ryan Lucy
Sabaretnam Suganya
Sabelhaus Timo
Sackrowitz Rachel
Sadera Girendra
Sadique Zia
Sagnier Anne
Saha Sian
Saint Martin Marjorie
Saito Hiroki
Saiyed Salim
Salahuddin Nawal
Salberg Armorel
Saleem Malik
Salhi Sara
Sall Jas
Salmon Charlotte
Salmon Karen
Saluja Rupali
Saluzzio Romina
Salvati Stefano
Sampson Julia
Sanders Arnate
Sanderson Amanda
Sandhu Gyan
Sanghavi Ritesh
Santamaria John
Santos Filipa
Santos Marlene S.
Sapsford David
Sara Treena
Saran Anita
Sathe Sonia
Sathianathan Kushaharan
Sathianathan Prasannakumari
Saull Michelle
Saunders Christina T.
Saunderson Paula
Sauras-Colón Esther
Saxena Manoj
Sayada Sarah
Sayehli Cyrus
Scanlan Jeremy
Scano Riccardo
Schaaf Bernhard
Schlegel Christian
Schmidhofer Mark
Schneider Francis
Schoenling Andrew
Scholl Denise
Schotsman Joost
Schouten Jeroen
Schueler Robert
Schuster-Bruce Martin
Schutgens Roger
Schweikert Sacha
Scott Kathryn
Scott Zoe
Scully Michael
Seaman Rebecca
Seidel Antje
Seidu Fatima
Seigne Patick
Sekiwala Rose
Sellers Katharine
Selmi Carlo
Sement Arnaud
Senya Ho
Seppelt Ian
Sernicola Elisa
Serri Karim
Sevilla Chanthou
Seymour Christopher W.
Shah Faraaz
Shahid Tasnin
Shaikh Arif
Shaikh Mohiuddin
Shakya Roshni
Shankar-Hari Manu
Sharma Deepak
Shaw David
Shaw Deborah
Shaw Joanne
Shearer Audrey
Sheath Ben
Sheffield Jonathan
Shehabi Yahya
Shekar Kiran
Shelton Sarah
Sherwood Nick
Shetty Varun
Shields Fiona
Shimabukuro-Vornhagen Alexander
Shintani Ayumi
Shirley Kim
Shovelton Charmaine
Shree Madhu
Shrestha Namrata
Shrestha Sabita
Shrestha Tapaswi
Shu Ki Lok Jennifer
Shyamsundar Murali
Siami Shidasp
Sibin Sindhu
Sicat Christine
Siddiqui Atif
Siddiqui Ayesha
Sidéris Georgios
Siewerski Chris
Siika Wangari
Sikondari Nyma
Silversides Jon
Sim Malcolm
Simmonds Catherine
Simons Koen
Simpson Benjamin
Simpson Joanna
Simpson Scott
Simpson Tom
Sinclair Julie-Ann
Singh Jayaprakash
Singh Rajeev
Singh Vanessa
Singler Karen
Singleton Jo
Sinha Pratik
Skinner Denise
Skinner Tabitha
Skorko Agnieszka
Skrtich Aimee
Slaughter Melanie
Slieker Kitty
Sligl Wendy
Sloan Andrew
Sloots-Cuppen Sonja
Small Charlotte
Smallshaw Karen
Smallwood Andrew
Smee Joanna
Smit Albertine
Smith Alex
Smith Catherine
Smith Eleanor
Smith Emma
Smith John
Smith Judith
Smith Julie
Smith Kerry
Smith Lucie
Smith Matthew
Smith Natalie
Smith Oliver
Smith Paul
Smith Simon
Smith Tim
Smuts Sara
Smyth Kirsty
Smyth Michelle
Smyth Naoise
Soar Natalie
Solesbury Amanda
Somerville Alastair
Song Rima
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Southern David
Southin Sara
Spain Sandra
Speight Holly
Spencer Kayleigh
Spencer Stephen
Spencer Thomas
Speyer Rebecca
Spiers Catriona
Spittle Nick
Spivey Michael
Spong Adam
Sprinckmoller Stefan
Squires Rebecca
Stambaugh Martha
Stammers Katie
Stanciu Delia
Stanley Timothy
Stanworth Simon
Stapleton Liana
Starke Lisa
Stavor Dara
Stedman Roger
Steffen Melanie
Stephanie Gelinotte
Stephens Deanna
Stevenson Lesley
Stewart Richard
Stienstra Riejanne
Stone Sarah
Stowe Bethan
Stratton Emma
Stronach Lucy
Suber Tomeka
Sukuraman Anila
Summerfield Anna
Summers Charlotte
Sundaram Radha
Sundaran Dhinesh
Sunkara Krishna
Surti Zuhra
Sutherland Helen
Sutherland Sara-Beth
Sutterlin Laetitia
Sutton Joanne
Sutu Mihaela
Sven?ek Franc
Svit?kar Nikolai
Swabe Jacqueline
Sweet Katie
Sy Eric
Szakmany Tamas
Szawarski Piotr
Tai Charlotte
Tait Jennifer
Talia Nadine
Tallott Mandy
Tamm Tina
Tamme Kadri
Taqdees Huda
Tarr Esther
Tate Margaret
Tatham Kate
Tavares Silvia
Taylor Holly
Taylor Melanie
Taylor Sian
Tee Ameila
Templeton Maie
Teo Hoon
Terrill Lenae
The Stephanie
Thedinga Karen
Thomas Amy
Thomas Ashly
Thomas Emma
Thomas Helen
Thomas Matt
Thomas Vicky
Thompson Patricia
Thompson Taylor
Thomson Nicola
Thrush Jessica
Thurairatnam Saranya
Tierney Carey
Tinmouth Alan
Tirot Patrice
Tlayjeh Haytham
Toffalo Sue
Tolppa Timo
Tomasi Enrico
Tomlinson Helen
Tong Steve
Tong Steven
Tony Kiran
Totzke Juliane
Touma Omar
Towns Miriam
Trapani Tony
Trask Kara
Traverse Eleanor
Trickey Jemma
Trim Fiona
Trimmer Ken
Triulzi Darrell
Troeman Darren
Trues Estefania
Truman Nicholas
Tsakiridou Kyriaki
Tsang Jennifer
Tsinaslanidis Georgios
Tuckwell Caroline
Tully Redmond
Tully Riona
Tung Raymond
Tupper-Carey Daryl
Turgeon Alexis F.
Turki Salah
Turner Anne M.
Turner Elizabeth
Turner Keri
Turner-Bone Ian
Turns Margaret
TV Bharath
Udayanga Ishara
Uddin Ruzena
Udy Andrew
Ullmann Hannah
Umrani Zulfiqar
Unsworth Adam
Uriel Alison
Ustianowski Andrew
Uyeki Tim
Vaara Suvi
Vaduganathan Muthiah
Vahtera Annukka
Vale Cassandra
Valentine Eliza
Vamplew Luke
van Amerongen Roosmarijn
van Bentum-Puijk Wilma
van Bree Sjoerd
van de Veerdonk Frank L.
van den Berg Lettie
van den Oever Huub
van der Eng Hetty
Van Der Heyden Kymbalee
van der Kraan-Donker Annemarie
van Gulik Laura
van Haren Frank
Van Hecke Jolien
van Kimmenade Roland
van Nieuwkoop Kees
van Zanten Arthur
van Zuylen Tamara
Van?t Hoff William
Vandewoestyne Sophie
Vanjak Christian
Vanmali Piyush
van Opdorp Marjolein
van Vonderen Marit
Vargas Jr. Jesus
Varghese Siby
Vautier Sarah
Vazquez-Grande Gloria
Veenith Tonny
Veillard Marion
Venkatesh Bala
Verlander Mark
Vermassen Joris
Vermeiren Daisy
Vermont - van der Staaij Janine
Verrier Nathalie
Vertue Mark
Verula Jerik
Victor Saji
Viehman Alex
Vieillard-Baron Antoine
Vignesh C
Villot Solenne
Vilá Clara
Vincent Rachel
Virdee Satwinder
Visentin Elisa
Visser Yorik
Vita Tina
Vivier Dominique
Vodovar Dominique
Voicu Sebastian
Voigt Ingo
Voiriot Guillaume
Volkov Lev
Voza Gennaro
Vuylsteke Alain
Wada Asako
Waddington Natalia
Wahl Nadine
Waite Alicia
Walden Andrew
Walker Gena
Walker Rachel
Walker Susan
Walsh Joanne
Walsh Tim
Walsham James
Walton Catherine
Wang Shu
Ward Geraldine
Ward Kathryn
Ward Luke
Warnapura Loku
Warnock Majella
Watchorn Olivia
Waters Abby
Waterson Sharon
Watkins Claire
Watpool Irene
Watters Malcolm
Watts Angela
Waugh Victoria
Webb Steve A.
Weber Lisa
Webster Denise
Weerasinghe Thanuja
Weismann Dirk
Weiss Daniel
Weissman Alexandra
Wells Alan
Wells Colin
Wells Karen
Welters Ingeborg
West Lauren
Westlake Samantha
Wetherill Bill
Wetzold Richard
Whileman Amanda
Whitbread Jennifer
White Alison
White Hayden
White Ian
White Katie
Whitehead Christina
Whitehouse Tony
Wibrow Bradley
Wigbers Jeanette
Wijewardena Gayathri
Wilby Elizabeth
Wilcox Elizabeth
Wilcox Louise
Wild Helen
Wild Laura
Wilding Laura
Wiles Matt
Wiley Daisy
Wilhelmsen Elva
Wilkinson Dean
Willams Felicity
Williams Alexandra
Williams Angharad
Williams Anna
Williams Erin
Williams Gemma
Williams Hannah
Williams Karen
Williams Marie
Williams Patricia
Williams Penny
Williams Tony
Williams Virginie
Williamson Dawn
Williamson James D
Willis Joanna
Willson Jayne
Wilson Anna
Wilson Craig
Wilson Jean
Wilson Maggie
Winters James
Winters Lauren
Wise Matt
Wisniewski Mary
Wittekamp Bastiaan
Wittenberg Wendy
Wnuk Chris
Woelke Amy
Wong Jenny
Wong Onyee
Wood Erica
Wood Hannah
Wood Tracy
Woods Jane
Woods Lindsey
Woodward Robert
Woolett Melissa
Worner Ruth
Wren Jess
Wren Lynn
Wrey Brown Caroline
Wright Chris
Wright Kim
Wunderley Renee
Wyatt Rachel
Wylie Katharine
Xavier Kugan
Yamagishi Yoshiaki
Yamashita Chizuru
Yang Yang
Yarad Elizabeth
Yates Bryan
Yates David
Yealy Donald
Young Ian
Young Meredith
Young Paul
Youngstein Taryn
Yu Haili
Yusuff Hakeem
Zaharia Mihaela
Zaidi Abbas
Zaki Ahmed
Zaman Mohsin
Zarychanski Ryan
Zdanavidiene Ausra
Zhao Xiao
Zinzoni Vanessa
Zitter Letizia
Zouita Louisa
Publication venue: 'American Medical Association (AMA)'
Publication date: 11/04/2023
Field of study

IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19. Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19. DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 non–critically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022). INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (n = 257), ARB (n = 248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; n = 10), or no RAS inhibitor (control; n = 264) for up to 10 days. MAIN OUTCOMES AND MEASURES The primary outcome was organ support–free days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes. RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ support–free days among critically ill patients was 10 (–1 to 16) in the ACE inhibitor group (n = 231), 8 (–1 to 17) in the ARB group (n = 217), and 12 (0 to 17) in the control group (n = 231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ support–free days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively). CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes. TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570

Online Research @ Cardiff

The Effect of International Involvement on the Relationship between Managerial Tenure and Firm Performance

Author: Ancona D.G.
Argyris C.
Bartlett C.A.
Bartlett C.A.
Bruce T. Lamont
Cohen J.
Dun
Galbraith J.
Gupta A.
Hambrick D.C.
Hambrick D.C.
Hoffman J.J.
Huber G.P.
James J. Hoff‐man
Kotter J.
Miles R.
O'Reilly C.
O'Reilly C.A.
Paul Simmonds
Pfeffer J.
Richard A. Lheureux
Schendel D.
Stevens J.
Tushman M.
Publication venue: 'Emerald'
Publication date
Field of study

Crossref

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Woosey D
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Wu P
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Xavier B
Xia Z
Yan M
Yanney M
Yasmin S
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Yates B
Yates D
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Yein K
Yelnoorkar F
Yip K
Ynter I
Yorke J
Youssouf S
Yousuf A
Yung B
Zafar A-M
Zaher S
Zalewska K
Zaman M
Zaman S
Zammit L
Zammit-Mangion M
Zdanaviciene A
Zehnde D
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Publication venue: 'Elsevier BV'
Publication date: 01/07/1994
Field of study

Controversy exists as to whether neoadjuvant chemotherapy improves survival in patients with invasive bladder cancer, despite randomised controlled trials of more than 3000 patients. We undertook a systematic review and meta-analysis to assess the effect of such treatment on survival in patients with this disease

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Measuring Access to Basic Services in Global Cities: Descriptive and Behavioral Approaches

Crossref

Impact of cross-section uncertainties on supernova neutrino spectral parameter fitting in the Deep Underground Neutrino Experiment

Author: Abed Abud A.
Abi B.
Acciarri R.
Acero M. A.
Adames M. R.
Adamov G.
Adamowski M.
Adams D.
Adinolfi M.
Adriano C.
Aduszkiewicz A.
Aguilar J.
Ahmad Z.
Ahmed J.
Aimard B.
Akbar F.
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Alonso Monsalve S.
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Alton A.
Alvarez R.
Amedo P.
Anderson J.
Andrade D. A.
Andreopoulos C.
Andreotti M.
Andrews M. P.
Andrianala F.
Andringa S.
Anfimov N.
Anicezio Campanelli W. L.
Ankowski A.
Antoniassi M.
Antonova M.
Antoshkin A.
Aranda-Fernandez A.
Arellano L.
Arnold L. O.
Arroyave M. A.
Asaadi J.
Ashkenazi A.
Asquith L.
Atkin E.
Auguste D.
Aurisano A.
Aushev V.
Autiero D.
Ayala-Torres M.
Azfar F.
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Back J. J.
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Balashov N.
Balasubramanian S.
Baldi P.
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Bambah B.
Banerjee R.
Barao F.
Barenboim G.
Barham Alzas P.
Barker G. J.
Barkhouse W.
Barnes C.
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Barranco Monarca J.
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Barrow J. L.
Basharina-Freshville A.
Bashyal A.
Basque V.
Batchelor C.
Battat J. B. R.
Battisti F.
Bay F.
Bazetto M. C. Q.
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Beacom J. F.
Bechetoille E.
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Beltramello O.
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Publication venue
Publication date: 01/01/2023
Field of study

A primary goal of the upcoming Deep Underground Neutrino Experiment (DUNE) is to measure the O(10) MeV neutrinos produced by a Galactic core-collapse supernova if one should occur during the lifetime of the experiment. The liquid-argon-based detectors planned for DUNE are expected to be uniquely sensitive to the νe component of the supernova flux, enabling a wide variety of physics and astrophysics measurements. A key requirement for a correct interpretation of these measurements is a good understanding of the energy-dependent total cross section σ(Eν) for charged-current νe absorption on argon. In the context of a simulated extraction of supernova νe spectral parameters from a toy analysis, we investigate the impact of σ(Eν) modeling uncertainties on DUNE's supernova neutrino physics sensitivity for the first time. We find that the currently large theoretical uncertainties on σ(Eν) must be substantially reduced before the νe flux parameters can be extracted reliably; in the absence of external constraints, a measurement of the integrated neutrino luminosity with less than 10% bias with DUNE requires σ(Eν) to be known to about 5%. The neutrino spectral shape parameters can be known to better than 10% for a 20% uncertainty on the cross-section scale, although they will be sensitive to uncertainties on the shape of σ(Eν). A direct measurement of low-energy νe-argon scattering would be invaluable for improving the theoretical precision to the needed level

Archivio della ricerca - Università degli studi di Napoli Federico II

ePubs: the open archive for STFC research publications

Archivio istituzionale della ricerca - Università di Padova

Highly-parallelized simulation of a pixelated LArTPC on a GPU

Author: Abed Abud A.
Abi B.
Acciarri R.
Acero M. A.
Adames M. R.
Adamov G.
Adamowski M.
Adams D.
Adinolfi M.
Adriano C.
Aduszkiewicz A.
Aguilar J.
Ahmad Z.
Ahmed J.
Aimard B.
Akbar F.
Allison K.
Alonso Monsalve S.
Alrashed M.
Alt C.
Alton A.
Alvarez R.
Amedo P.
Anderson J.
Andrade D. A.
Andreopoulos C.
Andreotti M.
Andrews M. P.
Andrianala F.
Andringa S.
Anfimov N.
Anicezio Campanelli W. L.
Ankowski A.
Antoniassi M.
Antonova M.
Antoshkin A.
Antusch S.
Aranda-Fernandez A.
Arellano L.
Arnold L. O.
Arroyave M. A.
Asaadi J.
Ashkenazi A.
Asquith L.
Aurisano A.
Aushev V.
Autiero D.
Ayala-Torres M.
Azfar F.
Back A.
Back H.
Back J. J.
Bagaturia I.
Bagby L.
Balashov N.
Balasubramanian S.
Baldi P.
Baldini W.
Baller B.
Bambah B.
Barao F.
Barenboim G.
Barham Alzas P.
Barker G. J.
Barkhouse W.
Barnes C.
Barr G.
Barranco Monarca J.
Barros A.
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Basharina-Freshville A.
Bashyal A.
Basque V.
Batchelor C.
Battat J. B. R.
Battisti F.
Bay F.
Bazetto M. C. Q.
Bazo Alba J. L. L.
Beacom J. F.
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Publication venue
Publication date: 01/01/2023
Field of study

The rapid development of general-purpose computing on graphics processing units (GPGPU) is allowing the implementation of highly-parallelized Monte Carlo simulation chains for particle physics experiments. This technique is particularly suitable for the simulation of a pixelated charge readout for time projection chambers, given the large number of channels that this technology employs. Here we present the first implementation of a full microphysical simulator of a liquid argon time projection chamber (LArTPC) equipped with light readout and pixelated charge readout, developed for the DUNE Near Detector. The software is implemented with an end-to-end set of GPU-optimized algorithms. The algorithms have been written in Python and translated into CUDA kernels using Numba, a just-in-time compiler for a subset of Python and NumPy instructions. The GPU implementation achieves a speed up of four orders of magnitude compared with the equivalent CPU version. The simulation of the current induced on 103 pixels takes around 1 ms on the GPU, compared with approximately 10 s on the CPU. The results of the simulation are compared against data from a pixel-readout LArTPC prototype

Archivio della ricerca - Università degli studi di Napoli Federico II

Archivio Istituzionale della Ricerca - Università degli Studi di Pavia

Long-term (180-Day) outcomes in critically Ill patients with COVID-19 in the REMAP-CAP randomized clinical trial

Author: Abbass H
Abdeladim L
Abdelhady H
Abdelkharim H
Abdelrazik M
Abdi Z
Abdukahil SA
Abel L
Abraham J
Abrahamson G
Abusamra Y
Aceto R
Adams P
Adebambo O
Adhikari N
Affleck J
Agha G
Aghemo A
Agno R
Aguilar-Dano A
Ahmad N
Ain Q
Ainscough K
Ainsworth J
Aitken L
Akamp C
Al Enezi F
Al-Bassam W
Al-Beidh F
Albert M
Albrett J
Alderink B
Alderman M
Alegria A
Alexander B
Alexander P
Alfonso J
Ali F
Ali M
Ali M
Allam H
Allen B
Allen L
Allibone S
AlQahtani S
Alswaidan L
Altaf W
Altomy M
Al Amri A
Al Qasim E
Amatya S
Ambrosino R
Anders J
Anderson T
Andreae M
Andric Z
Aneman A
Angus DC
Anjum A
Ankert J
Annane D
Anne-Laure F
Anstey M
Antcliffe D
Anthony A
Antoine M
Antoine P
Anumakonda V
Aparicio C
Arabi YM
Arachchige M
Aravindan L
Arbane G
Archer S
Aref N
Arias A-M
Arias S
Arishi H
Arnold D
Arnold J
Aryal D
Asghar A
Asif N
Aspinwall A
Attanayaka U
Attokaran A
Attwood B
Au C
Austin K
Austin P
Avard B
Awan S
Azaiz A
Azergui N
Azzaui H
Babel J
Babu S
Bacon G
Badalamenti S
Badie J
Bagavathy K
Bagot C
Bagshaw S
Baig N
Baikady R
Baillie K
Bain W
Baker E
Baker S
Bakthavatsalam D
Balaie M
Bamford A
Bamford P
Banach D
Bannard-Smith J
Barbash I
Barbazza L
Barber R
Barbier F
Barge D
Bari S
Bariola R
Barker G
Barnes N
Baron R
Barreau A
Bart R
Bartholomew J
Bartley S
Barton D
Barton F
Bashyal A
Basile K
Bass F
Bassford C
Bastola S
Bastos JMPS
Bates M
Bates S
Batista TMO
Bauchmuller K
Bayne M
Bean S
Beane A
Beard G
Beasley R
Beavis S
Beddows S
Bedford C
Beer D
Begin P
Begum S
Bell G
Bellemare D
Beltran M
Bendjemar L
Benettaib F
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Berry LR
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Walsh L
Walsh T
Walsham J
Wang S
Ward G
Ward K
Ward L
Warnapura L
Warnock M
Watchorn O
Waters A
Waterson S
Watkins C
Watpool I
Watts A
Waugh V
Webb SA
Weber L
Weerasinghe T
Weismann D
Weiss D
Weissman A
Wells C
Welters I
Westlake S
Wetherill B
Wetzold R
Whileman A
Whitbread J
White A
White H
White I
White K
Whitehead C
Whitehouse T
Wibrow B
Wigbers J
Wilby E
Wilcox E
Wilcox L
Wild H
Wild L
Wilding L
Wiles M
Wiley D
Wilhelmsen E
Wilkinson D
Willams F
Williams A
Williams A
Williams A
Williams E
Williams G
Williams H
Williams K
Williams P
Williams P
Williams T
Williams V
Williamson D
Williamson JD
Willis J
Willson J
Wilson A
Wilson C
Wilson M
Winters J
Winters L
Wise M
Wiseman S
Wisniewski M
Wittenberg W
Wnuk C
Woelke A
Wong H
Wong O
Wood E
Wood H
Wood T
Woods J
Woods L
Worner R
Wren J
Wren L
Wrey Brown C
Wright C
Wunderley R
Wyatt R
Wylie K
Xavier K
Yang Y
Yarad E
Yates D
Yealy D
Young C
Young I
Young M
Young P
Youngstein T
Yu H
Yusuff H
Zaharia M
Zaidi A
Zaki A
Zaman M
Zapalac M
Zarychanski R
Zhao X
Zinzoni V
Zitter L
Zouita L
Publication venue: 'American Medical Association (AMA)'
Publication date: 30/11/2022
Field of study

Importance The longer-term effects of therapies for the treatment of critically ill patients with COVID-19 are unknown. Objective To determine the effect of multiple interventions for critically ill adults with COVID-19 on longer-term outcomes. Design, Setting, and Participants Prespecified secondary analysis of an ongoing adaptive platform trial (REMAP-CAP) testing interventions within multiple therapeutic domains in which 4869 critically ill adult patients with COVID-19 were enrolled between March 9, 2020, and June 22, 2021, from 197 sites in 14 countries. The final 180-day follow-up was completed on March 2, 2022. Interventions Patients were randomized to receive 1 or more interventions within 6 treatment domains: immune modulators (n = 2274), convalescent plasma (n = 2011), antiplatelet therapy (n = 1557), anticoagulation (n = 1033), antivirals (n = 726), and corticosteroids (n = 401). Main Outcomes and Measures The main outcome was survival through day 180, analyzed using a bayesian piecewise exponential model. A hazard ratio (HR) less than 1 represented improved survival (superiority), while an HR greater than 1 represented worsened survival (harm); futility was represented by a relative improvement less than 20% in outcome, shown by an HR greater than 0.83. Results Among 4869 randomized patients (mean age, 59.3 years; 1537 [32.1%] women), 4107 (84.3%) had known vital status and 2590 (63.1%) were alive at day 180. IL-6 receptor antagonists had a greater than 99.9% probability of improving 6-month survival (adjusted HR, 0.74 [95% credible interval {CrI}, 0.61-0.90]) and antiplatelet agents had a 95% probability of improving 6-month survival (adjusted HR, 0.85 [95% CrI, 0.71-1.03]) compared with the control, while the probability of trial-defined statistical futility (HR >0.83) was high for therapeutic anticoagulation (99.9%; HR, 1.13 [95% CrI, 0.93-1.42]), convalescent plasma (99.2%; HR, 0.99 [95% CrI, 0.86-1.14]), and lopinavir-ritonavir (96.6%; HR, 1.06 [95% CrI, 0.82-1.38]) and the probabilities of harm from hydroxychloroquine (96.9%; HR, 1.51 [95% CrI, 0.98-2.29]) and the combination of lopinavir-ritonavir and hydroxychloroquine (96.8%; HR, 1.61 [95% CrI, 0.97-2.67]) were high. The corticosteroid domain was stopped early prior to reaching a predefined statistical trigger; there was a 57.1% to 61.6% probability of improving 6-month survival across varying hydrocortisone dosing strategies. Conclusions and Relevance Among critically ill patients with COVID-19 randomized to receive 1 or more therapeutic interventions, treatment with an IL-6 receptor antagonist had a greater than 99.9% probability of improved 180-day mortality compared with patients randomized to the control, and treatment with an antiplatelet had a 95.0% probability of improved 180-day mortality compared with patients randomized to the control. Overall, when considered with previously reported short-term results, the findings indicate that initial in-hospital treatment effects were consistent for most therapies through 6 months

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