Atmospheric emissions of volatile organic compounds from a mine soil treated with sewage sludge and tomato plants (Lycopersicum esculentum l.)

The study investigated the emissions of volatile organic compounds (VOCs) from a mining soil amended with sewage sludge and irrigated with wastewater with or without tomato plants. The aim is to find out whether amendment and irrigation change VOC emissions from the soil and whether tomato changes emissions compared to uncultivated soil. Soil and plant experiments were done in assembled pots. All pots were placed inside a closed glass chamber inside an isolated and windowless room. Experiments with soil without plants were done independently from experiments with soil and plants. An aspirating pump coupled with Tenax adsorbent tubes was used for sampling of VOCs emitted from pots. Volatile organic compounds trapped in the tubes were quantified by gas chromatography–mass spectrometry detection. The study detected a total of nine VOCs emitted from the polluted soil: benzene, toluene, ethylbenzene, p-xylene, m-xylene, o-xylene, styrene, benzene-1,2,4-trimethyl and tetrachloroethylene, among which the most abundant were toluene, m-xylene and styrene. Differences between pots with or without amendments (C and A-pots) showed a general tendency to a decline of VOCs emissions in the mining soil amended with sewage sludge. Plants contributed to increase significantly the emissions of all VOCs in both A and C-pots. The soil amended with sewage sludge reduced the emission of VOCs: styrene in pots without plants and benzene and xylenes in pots with plants. Tomato plants contributed to increase significantly the emissions of all VOCs except styrene in both amended and non-amended soils. © 2022, The Author(s).Junta de Andalucía P10-RNM5814European Commission (EC). Fondo Europeo de Desarrollo Regional (FEDER) P10-RNM581

Effects of regularly consuming dietary fibre rich soluble cocoa products on bowel habits in healthy subjects: a free-living, two-stage, randomized, crossover, single-blind intervention

Abstract Background Dietary fibre is both preventive and therapeutic for bowel functional diseases. Soluble cocoa products are good sources of dietary fibre that may be supplemented with this dietary component. This study assessed the effects of regularly consuming two soluble cocoa products (A and B) with different non-starch polysaccharides levels (NSP, 15.1 and 22.0% w/w, respectively) on bowel habits using subjective intestinal function and symptom questionnaires, a daily diary and a faecal marker in healthy individuals. Methods A free-living, two-stage, randomized, crossover, single-blind intervention was carried out in 44 healthy men and women, between 18-55 y old, who had not taken dietary supplements, laxatives, or antibiotics six months before the start of the study. In the four-week-long intervention stages, separated by a three-week-wash-out stage, two servings of A and B, that provided 2.26 vs. 6.60 g/day of NSP respectively, were taken. In each stage, volunteers' diet was recorded using a 72-h food intake report. Results Regularly consuming cocoa A and B increased fibre intake, although only cocoa B significantly increased fibre intake (p < 0.001) with respect to the non-cocoa stage. No changes in body weight were observed in either of the 4 week interventions. With cocoa product B, the number of daily bowel movements increased (p = 0.002), the frequency of having a bowel movement once a day increased (p = 0.009), the time to have a bowel movement was lower (p = 0.016) as well as the feeling of constipation (p = 0.046) without inducing adverse gastrointestinal symptoms, only flatulence increased (p = 0.019). Conclusions Regular consumption of the cocoa products increases dietary fibre intake to recommended levels and product B improves bowel habits. The use of both objective and subjective assessments to evaluate the effects of food on bowel habits is recommended.Projects AGL2007-64042 and Consolider-Ingenio (CSD2007-00063) from the Spanish Ministry of Science and Innovation also acknowledged. S.M.-L. is a JAE-Predoc fellow of CSIC Programme "Junta para la Ampliación de Estudios" co-funded by the European Social Fund (ESF). M.G.-J. is a predoctoral fellow of the Spanish Ministry of Science and Innovation. A.F.-E. was a FINNOVA fellow also cofinanced by CSIC and the ESF.Peer Reviewe

Experience with Sunitinib in metastatic renal cell carcinoma (mRCC) patients: pooled analysis from 3 Spanish observational prospective studies

[Abstract] Background: A pivotal, randomized, phase III trial demonstrated a statistically significant superiority of sunitinib over interferon-α in metastatic renal cell carcinoma (mRCC) patients. Objective: To evaluate the effectiveness and safety of sunitinib in patients with advanced or mRCC in routine clinical practice. Methods: Retrospective pooled analysis of clinical data from three observational and prospective studies carried out between 2007 and 2011 in 33 Spanish hospitals. Tumor response, Progression-free survival (PFS) and overall survival (OS), and main sunitinib-related toxicities were registered. Results: 224 patients were analyzed. Median PFS 10.6 months (95% CI: 9.02–12.25), median OS 21.9 months (95% CI: 17.2–26.6). Objective response rate (ORR) 43.8% (95% CI: 36.8–50.7). Median time to PR was 3.8 months (95% CI: 3.86–5.99) and to CR 8.2 months (95% CI: 4.75–9.77). The most common ≥ grade-3 AEs were asthenia/fatigue (18.7%), hand-foot syndrome (6.2%), hypertension (5.8%) and neutropenia (4.8%). Hand-foot syndrome, diarrhea and mucositis were confirmed as independent predictors for PFS and/or OS in a multivariate analysis (p < 0.05) Conclusions: Outcomes with sunitinib in daily clinical practice resemble those obtained in clinical trials. Long-term benefit with sunitinib is possible in advanced RCC patients but the appropriate management of toxicities is mandatory to enable patients to remain on treatment

¡Atención Poli, con la vista en el riesgo! cuentos para seguritos

El contar historias o el storytelling, aparece como una herramienta para autores que no solo buscan el conectar de forma más auténtica con sus lectores; sino que buscan ir más allá al comprender cómo el cerebro procesa esta poderosa forma de comunicación. (Suzuki, W., Feliú-Mójer, M., Hasson, U., Yehuda, R., &amp; Zarate, J. 2018). Esta nueva forma de contar algo, es presentada aquí, en la primera compilación de cuentos como resultado de trabajos de módulos que tratan sobre el cuerpo humano, donde el estudio y la comprensión de la forma cómo funciona nuestro organismo, es uno de los principales objetivos. Además, surge como estrategia pedagógica, que precisamente busca incentivar el desarrollo de la creatividad de los estudiantes dentro de módulos que contienen un importante abordaje de temas y conceptos como base para su desarrollo, módulos que, al incluir un alto contenido teórico, se presentan como retos para que sus temas sean interiorizados por los estudiantes. De este modo, cuando se acude a el uso de la creatividad a través del storytelling, donde se expresan ideas relacionadas con el cuerpo humano, los cuentos realizados por estudiantes aquí presentes logran mostrar cómo emplean dichos conocimientos adquiridos, organizan ideas y crean cuentos que permiten al lector recrease, conociendo diferentes aspectos sobre nuestro cuerpo y a su vez dejándose llevar por la imaginación de los autores

Effects of regularly consuming dietary fibre rich soluble cocoa products on bowel habits in healthy subjects: a free-living, two-stage, randomized, crossover, single-blind intervention

Abstract Background Dietary fibre is both preventive and therapeutic for bowel functional diseases. Soluble cocoa products are good sources of dietary fibre that may be supplemented with this dietary component. This study assessed the effects of regularly consuming two soluble cocoa products (A and B) with different non-starch polysaccharides levels (NSP, 15.1 and 22.0% w/w, respectively) on bowel habits using subjective intestinal function and symptom questionnaires, a daily diary and a faecal marker in healthy individuals. Methods A free-living, two-stage, randomized, crossover, single-blind intervention was carried out in 44 healthy men and women, between 18-55 y old, who had not taken dietary supplements, laxatives, or antibiotics six months before the start of the study. In the four-week-long intervention stages, separated by a three-week-wash-out stage, two servings of A and B, that provided 2.26 vs. 6.60 g/day of NSP respectively, were taken. In each stage, volunteers' diet was recorded using a 72-h food intake report. Results Regularly consuming cocoa A and B increased fibre intake, although only cocoa B significantly increased fibre intake (p Conclusions Regular consumption of the cocoa products increases dietary fibre intake to recommended levels and product B improves bowel habits. The use of both objective and subjective assessments to evaluate the effects of food on bowel habits is recommended.</p

A comparative study of the effects of regularly consuming two cocoa products with different polyphenols levels on cardiovascular health in humans.

Cardioprotective effects 01 cocoa, mainly because 01 its content in polyphenols (PP), are well known. Moreover, these highly consumed products may be enriched with PP and Ihus acquire added valued Irom a healihwise viewpoint which is relevant to examine. In order to assess the effecls 01 two soluble cocoa products, containing 25.4 9 PP/g (CCl) and 13.88 mg PP/g (CCF), on cardiovascular heallh, a crossover, randomized, double-blind study was carried out in normocholesterolemic (n=24) and hypercholesterolemic (n=20, Ch> 200mg/dl) men and women. aged 18-45. non­ smoker and non-vegetarian. nol on medication. Volunteers ingested 15 9 01 CCl or 30 gol CCF, which provided 380 and 430 mg PP/day respectively. in 200 ml 01 delalted­ milk. lor 28 days. A 21 days wa sh-oul period separated the interventions. During the whole study polyphenol rich lood was restricted lrom volunteer's die!. In each stage, blood samples were collected at the slart and the end to assess total, HDL and lDl­ Cholesterol, triglycerides, glucose, ORAC. FRAP, ABTS and peroxidalion biomarkers (malonyldialdehyde and carbonyl groups). Also, blood pressure and heart rale were measured and their intake was assessed using a 72-hour dielary recal!. Results: Were slalistically studied using a mix model with repeated measures and a Bonlerroni test within each group. A significanlly decrease in glucose (p= 0.023) was observed in both groups when cocoa products were consumed. HDL-Cholesterol was significantiy higher with both cocoa products (p= 0.001). ORAC increased with CCl in normocholesterolemic group (p= 0.006) and with CCF in hypercholesterolemíc (p=0.024). Peroxidalion biomarKers were slightly lower with cocoa products. being carbonyl groups significantiy lower in hypercholesterolemlc group after consumlng CCL (p= 0.016). The olher parameters did nol show significant differences. . Conclusion: regular consumption 01 both cocoa products produces hypoglycemlc effects. reduces the risk 01 cardiovascular disease and protecls against oxidalive stressPeer Reviewe

Establishment of a vegetative cover in a mine soil added with urban sewage sludges

4 páginas.-- 3 figuras.-- 1 tabla.-- 8 referencias.-- Ponencia presentada en el VI Congreso Ibérico de la Ciencia del Suelo . Santiago de Compostela 22 al 25 de junio de 2014.The effect of three different urban sewage sludges on the establishment of three different species (ray-grass, tomato and ahipa) was investigated. The treatments were: air-dried stabilized sewage sludge, composted and composted with olive prune wastes. Soil pH was only slightly modified but soil conductivity moderately increased with the addition of sludges, always below 1.2 dS m-1, without interfering with seed germination. The organic carbon content increased with sludge application, more for air-dried stabilized than for composted sewage sludges. The plant species responded differently to sludge treatments. In ahipa, the treatments only affected the leaf photosynthetic pigments but not the plant growth. In tomato 2% sludge enhanced chlorophyll a content in leaves, but sludges at 10% either increased plant mortality or did not improve plant growth.Peer reviewe

Luminescent complexes of iridium(iii) with aliphatic amines and detection of biogenic amines

The straightforward reaction of [Ir2(ppy)4(µ-Cl)2] with an excess of aliphatic amines yields luminescent iridium complexes of general formula [IrCl(ppy)2(amine)] [amine = n-octylamine (1), t-butylamine (2), piperidine (3)]. The higher sterical hindrance of the amine in complex 2 was the responsible of its equilibrium with the starting materials. The luminescence of 1 and 3 has been studied showing emission at 508 and 509 nm respectively. As the aliphatic amines can be considered models of biogenic amines, this luminescence has been used to explore the viability of this reaction in the detection of biogenic amines. The exposition to vapors of biogenic amines of a solution of [Ir2(ppy)4(µ-Cl)2] in CH2Cl2 or in different solid supports, showed that it was possible to detect the amines in a quick and easy way, with limits of detection value (in solution of methylene chloride) of 4.8 µM for cadaverine.Ministerio de Economía y Competitividad, Spain (Project CTQ2015-71353-R), Junta de Castilla y León, Consejería de Educación y Cultura y Fondo Social Europeo (Project BU263P18) and Junta de Castilla y León, Consejería de Educación (Project BU087G19

Protecting effect of recycled urban wastes (sewage sludge and wastewater) on ryegrass against the toxicity of pesticides at high concentrations

Degraded landscapes, like those from abandoned mine areas, could be restored by revegetating them with appropriate plant species, after correction for acidity and improvement by adding exogenous organic material. Application of urban wastes to large areas of derelict land helps in the sustainable development of this landscape. However, the development of plant species in these soils could require in the future the management of possible pests or diseases by pesticide applications which could also affect plant yield. Therefore, ryegrass (Lolium perenne L.) was planted in a limed soil from the mining area of Riotinto (SW Spain), using an indoor pot experiment and the effects of amendment with sewage sludge, as well as irrigation with urban wastewater on plant uptake of the insecticide thiacloprid and the fungicide fenarimol were examined. Ryegrass biomass was reduced up to 3-fold by pesticide application. Fenarimol residues were the highest in soil, while those of thiacloprid were lower in soil and higher in ryegrass. Addition of sewage sludge and irrigation with wastewater led to a reduction of pesticide translocation to the aerial plant parts, representing a lower hazard to ryegrass quality grown in this mine soil.Junta de Andalucía P10-RNM581