2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS guideline for the diagnosis and management of patients with stable ischemic heart disease

The recommendations listed in this document are, whenever possible, evidence based. An extensive evidence review was conducted as the document was compiled through December 2008. Repeated literature searches were performed by the guideline development staff and writing committee members as new issues were considered. New clinical trials published in peer-reviewed journals and articles through December 2011 were also reviewed and incorporated when relevant. Furthermore, because of the extended development time period for this guideline, peer review comments indicated that the sections focused on imaging technologies required additional updating, which occurred during 2011. Therefore, the evidence review for the imaging sections includes published literature through December 2011

Subclinical LV dysfunction influences outcome: Association of abnormal myocardial deformation and mortality independent of hypertrophy and in the absence of ischaemia

Peak systolic strain rate (SR) has been proposed as a means for quantifying dobutamine stress echocardiography (DSE). However, myocardial deformation may be influenced by other processes including left ventricular hypertrophy (LVH). This study sought to investigate the effect of LVH on myocardial deformation at dobutamine stress echocardiography (DSE)