An analytical longitudinal observational study on the association of Vitamin D insufficiency in subjects with primary (idiopathic) demyelinating optic neuritis using visual evoked potential and optical coherence tomography

Background: Optic neuritis (ON) is an acute and often immune-mediated inflammatory condition of the optic nerve. Vitamin D acts as an anti-inflammatory agent and may confer neuroprotection. Visual evoked potential (VEP) and optical coherence tomography (OCT) are emerging tools for demyelinating diseases. Aims and Objectives: We tried to correlate between Vitamin D insufficiency and acute demyelinating ON using different parameters such as VEP, ganglion cell layer (GCL) thickness, and retinal nerve fiber layer (RNFL) thickness. Materials and Methods: This observational longitudinal analytical study included thirty non-consecutive patients with primary ON and 30 healthy controls. All patients with ON underwent detailed clinical and ophthalmological examination, and detailed blood workup, including serum 25 (OH) Vitamin D. VEP P100 latency, amplitude, OCT, RNFL thickness, and GCL thickness at presentation and after 3 months from May 2019 to November 2020. Results: Vitamin D insufficiency (below 30 ng/mL) was present in 60% of cases of ON. The baseline VEP showed significantly prolonged P100 latency in affected eyes in the Vitamin D insufficient group (mean 129.78±7.97 ms vs. 121.0±4.99 ms) whereas the P100 amplitude was not significantly altered between the two groups (5.5±3.13 μV vs. 7.08±3.01 μV). The baseline RNFL thickness (132.21±10.69 μm vs. 118.01±10.4 μm) and GCL thickness (76.82±2.04 μm vs. 73.06±3.2 μm) were greater in affected eyes of vitamin D insufficiency ON. There was greater RNFL thinning (79.93±3.42 μm vs. 74.80±3.5 μm) and GCL thinning (64.78±1.9μm vs. 69.02±2.22 μm) in affected eyes of ON with Vitamin D insufficiency at 3 months. Conclusion: Vitamin D insufficiency was found in most cases of ON. Insufficient Vitamin D positively correlated with optic nerve affection severity as evidenced by significantly increased baseline thickness of RNFL and GCL and more thinning of RNFL and GCL at the end of 3 months of follow-up

withdrawn 2017 hrs ehra ecas aphrs solaece expert consensus statement on catheter and surgical ablation of atrial fibrillation

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Biodegradable compatibilized polymer blends for packaging applications A literature review

The majority of materials used for short-term and disposable packaging application are non-biodegradable which are not satisfying the demands in environmental safety and sustainability. Biodegradable polymers are an alternative for these non-biodegradable materials. The biodegradable polymeric materials can degrade in a reasonable time period without causing environmental problems. However, biodegradable polymers possess some limitations such as comparatively high cost, insufficient mechanical performances, and inferior thermal stability to extend their widespread application in packaging industry. To overcome these limitations, one of the most commonly used strategies is melt blending of dissimilar biodegradable polymers. Unfortunately, most of the biodegradable polymer blends exhibit insufficient performance because they are thermodynamically immiscible as well as exhibit poor compatibility between the blended components. It has been established that the compatibilization is a well-known strategy to improve the performances of the immiscible biodegradable polymer blends by enhancing the adhesion between the phases. As a result, recent studies focus on various compatibilizers to enhance the performances of the resulting biodegradable polymer blends. This review summarizes the recent developments on a variety of biodegradable polymer blends compatibilized by melt processing with a main focus of ex situ and in situ compatibilization strategies. (C) 2017 Wiley Periodicals, Inc

A Review on Current Status of Biochar Uses in Agriculture

In a time when climate change increases desertification and drought globally, novel and effective solutions are required in order to continue food production for the world’s increasing population. Synthetic fertilizers have been long used to improve the productivity of agricultural soils, part of which leaches into the environment and emits greenhouse gasses (GHG). Some fundamental challenges within agricultural practices include the improvement of water retention and microbiota in soils, as well as boosting the efficiency of fertilizers. Biochar is a nutrient rich material produced from biomass, gaining attention for soil amendment purposes, improving crop yields as well as for carbon sequestration. This study summarizes the potential benefits of biochar applications, placing emphasis on its application in the agricultural sector. It seems biochar used for soil amendment improves nutrient density of soils, water holding capacity, reduces fertilizer requirements, enhances soil microbiota, and increases crop yields. Additionally, biochar usage has many environmental benefits, economic benefits, and a potential role to play in carbon credit systems. Biochar (also known as biocarbon) may hold the answer to these fundamental requirements

High biomass filled biodegradable plastic in engineering sustainable composites

The production of single-use, non-renewable plastic has persistently impacted the environment through non-biodegradable plastic accumulation. Injection-moulded biodegradable polymer blend [poly(butylene succinate-co-butylene-adipate) (PBSA) and poly(butylene adipate-co-terephthalate) (PBAT)] with an inexpensive filler, walnut shell powder (WSP), enables an appropriate melt flow behaviour after incorporating compatibilizer as confirmed by rheological analysis. The sustainable composites with 60 wt% WSP showed a decrement of 68.4% in tensile strength as compared to PBSA/PBAT blend. However, the inclusion of a 5 wt% compatibilizer in PBSA/PBAT/60wt%WSP composite increased tensile strength by 48.7%, indicating improved interfacial adhesion. Further, the improvements in tensile (694%) and flexural moduli (461%) of PBSA/PBAT blend were observed with the addition of 60 wt% WSP in presence of 7 wt% compatibilizer due to fibrillar morphology of filler. Thus, signifying enhanced stiffness with increased filler, leading to a composite suitable for rigid packaging. Scanning electron microscopy (SEM) confirmed an improved adhesion between matrix and filler interfaces with the addition of a compatibilizer as gaps decreased, subsequently leading to increased mechanical properties. The novelty of this work establishes a high loading of filler can be incorporated with biodegradable polymers and improved properties in presence of compatibilizer makes it more suitable for injection moulding applications to produce a low-cost biocomposite capable of being used as a single-use plastic alternative in rigid packaging

Handbook of Polymernanocomposites. Processing, Performance and ApplicationVolume A: Layered Silicates /

XII, 538 p. 209 illus., 58 illus. in color.onlin