686 research outputs found
The relative importance of forest cover and patch-level drivers for phyllostomid bat communities in the Amazonian Savannas
Context: Analyze the multiple dimensions of biodiversity under a local and landscape lens in natural habitats, such as Amazonian savannas, is fundamental for the conservation of species and ecosystems. Objectives: We aim to explore how landscape forest cover and patch-level variables affect the patterns of species abundance, functional traits, and taxonomic, functional and phylogenetic α-diversity of Phyllostomid bats in forest patches of the Savannas of Amapå, in both the wet and dry seasons. Methods: We used mist nets to survey bats in 26 forest patches. We also quantified forest cover in buffers of 500, 1000, 1500, 2000 and 2500 m around each patch, and tree height, basal area, canopy cover, and vegetation clutter in the understorey at the patch level. We used hierarchical partitioning to relate the different indices with our predictor variables. Results: Taxonomic, functional and phylogenetic diversity in the wet season increased with the proportion of forest cover in the 2500 m buffer. Vegetation clutter was negatively related to taxonomic and functional diversity in the wet season. In the dry season, average tree height positively affected taxonomic and functional diversity. Patch-level variables were more important than forest cover in explaining the average functional traits in both seasons. Conclusion: We found seasonal variation in the relationships between components of bat diversity and different drivers. Since both forest cover in the landscape and patch-level variables are important for Phyllostomid bat diversity, conservation plans should consider forest conservation at the landscape level and maintenance of forest patch qualityOpen Access funding provided thanks to the
CRUE-CSIC agreement with Springer Nature. Part of the data
used in this study was supported by Neotropical Grassland
Conservancy (01098803-5), National Geographic Society (EC59186R-19 and NGS-83254R-20), Bat Conservation International (2434131) and Ruford Foundation (25585-1
ANĂLISE DO COMPORTAMENTO DO CONCRETO REFORĂADO COM FIBRA DE CARBONO POR MEIO DO ENSAIO DE COMPRESSĂO
Introdução: As estruturas de concreto armado podem apresentar a necessidade de serem reforçadas, em razĂŁo de algumas falhas de projetos ou atĂ© mesmo o uso inadequado durante sua vida Ăștil. Atualmente, existem vĂĄrios tipos de materiais que podem ser utilizados para o reforço estrutural. O uso dos materiais compĂłsitos, como o tecido de fibra de carbono, surge como uma tecnologia que possui caracterĂsticas inovadoras, destacando-se em aplicaçÔes como o reforço das estruturas de concreto armado jĂĄ existentes. Objetivo: Elaborar uma anĂĄlise experimental em corpos de prova cilĂndricos de concreto com a aplicação do tecido de fibra de carbono, objetivando verificar as alteraçÔes em relação a resistĂȘncia Ă compressĂŁo axial, para comprovar se o tecido de fibra de carbono Ă© uma opção viĂĄvel para o reforço estrutural. Material e MĂ©todos: O foco do estudo pautou-se na experimentação em laboratĂłrio visando verificar a influĂȘncia que a manta de fibra de carbono apresenta no concreto como material de reforço estrutural. Para a realização do ensaio, foram moldados corpos de prova cilĂndricos nas dimensĂ”es de 10 cm de diĂąmetro e 20 cm de altura, obedecendo o especificado da Associação Brasileira de Normas TĂ©cnicas â ABNT, NBR 5738:2015 â Corrigida 2016. Ao todo foram moldados 8 corpos de prova onde, apĂłs o processo de cura de 28 dias, 4 receberam o reforço por meio do tecido de fibra de carbono e 4 foram mantidos em suas condiçÔes originais, para posterior comparação. Passando-se 24 horas apĂłs a aplicação do tecido, espera-se que os elementos jĂĄ apresentem resistĂȘncias maiores, porĂ©m, foi atendido o prazo de cura de 7 dias especificado pelo fabricante do tecido. ApĂłs os 7 dias do processo de cura, efetuou-se o ensaio de compressĂŁo axial em laboratĂłrio credenciado, seguindo o disposto na ABNT NBR 5739:2018. A idade dos corpos de prova ensaiados foi de 36 dias, sendo rompidos aproximadamente 20 horas apĂłs a sua retirada da solução de hidrĂłxido de cĂĄlcio, conforme Tabela 2 â TolerĂąncia de tempo para o ensaio de compressĂŁo em função da idade de ruptura, apresentada na NBR 5739:2018. O equipamento utilizado para o ensaio apresentava o sistema digital de medição de força, mantendo a taxa de tensĂŁo no intervalo de 0.45MPa/s. No ensaio dos corpos de prova sem o tecido, atingiu-se as resistĂȘncias de 36.20MPa, 38.20MPa, 35.00MPa e 41.50MPa. Os corpos de prova reforçados apresentaram 52.39Mpa, 55.80 Mpa, 62.00MPa e 65.90Mpa, respectivamente, sendo os dois Ășltimos reforçados com duas camadas do tecido e os dois primeiros com apenas uma camada. ConsideraçÔes: Pelo mĂ©todo de anĂĄlise comparativa, comprovou-se o significativo ganho de resistĂȘncia dos corpos de prova ensaiados, apresentando um aumento mĂ©dio de 58,42% da mesma. As pesquisas realizadas ao longo do trabalho demonstraram a eficiĂȘncia do reforço, considerando que todos os corpos de provas reforçados, apresentaram aumento de sua resistĂȘncia. Diante disso, os materiais compĂłsitos se apresentam no mercado brasileiro como alternativa tecnolĂłgica eficiente para o reforço de estruturas de concreto
Pervasive gaps in Amazonian ecological research
Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4
While the increasing availability of global databases on ecological communities has advanced our knowledge
of biodiversity sensitivity to environmental changes,5â7 vast areas of the tropics remain understudied.8â11 In
the American tropics, Amazonia stands out as the worldâs most diverse rainforest and the primary source of
Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13â15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazonâs biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus
crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced
environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian
Amazonia, while identifying the regionâs vulnerability to environmental change. 15%â18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by
2050. This means that unless we take immediate action, we will not be able to establish their current status,
much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio
Large expert-curated database for benchmarking document similarity detection in biomedical literature search
Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical research.Peer reviewe
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Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.
Importance: Evidence regarding corticosteroid use for severe coronavirus disease 2019 (COVID-19) is limited. Objective: To determine whether hydrocortisone improves outcome for patients with severe COVID-19. Design, Setting, and Participants: An ongoing adaptive platform trial testing multiple interventions within multiple therapeutic domains, for example, antiviral agents, corticosteroids, or immunoglobulin. Between March 9 and June 17, 2020, 614 adult patients with suspected or confirmed COVID-19 were enrolled and randomized within at least 1 domain following admission to an intensive care unit (ICU) for respiratory or cardiovascular organ support at 121 sites in 8 countries. Of these, 403 were randomized to open-label interventions within the corticosteroid domain. The domain was halted after results from another trial were released. Follow-up ended August 12, 2020. Interventions: The corticosteroid domain randomized participants to a fixed 7-day course of intravenous hydrocortisone (50 mg or 100 mg every 6 hours) (nâ=â143), a shock-dependent course (50 mg every 6 hours when shock was clinically evident) (nâ=â152), or no hydrocortisone (nâ=â108). Main Outcomes and Measures: The primary end point was organ support-free days (days alive and free of ICU-based respiratory or cardiovascular support) within 21 days, where patients who died were assigned -1 day. The primary analysis was a bayesian cumulative logistic model that included all patients enrolled with severe COVID-19, adjusting for age, sex, site, region, time, assignment to interventions within other domains, and domain and intervention eligibility. Superiority was defined as the posterior probability of an odds ratio greater than 1 (threshold for trial conclusion of superiority >99%). Results: After excluding 19 participants who withdrew consent, there were 384 patients (mean age, 60 years; 29% female) randomized to the fixed-dose (nâ=â137), shock-dependent (nâ=â146), and no (nâ=â101) hydrocortisone groups; 379 (99%) completed the study and were included in the analysis. The mean age for the 3 groups ranged between 59.5 and 60.4 years; most patients were male (range, 70.6%-71.5%); mean body mass index ranged between 29.7 and 30.9; and patients receiving mechanical ventilation ranged between 50.0% and 63.5%. For the fixed-dose, shock-dependent, and no hydrocortisone groups, respectively, the median organ support-free days were 0 (IQR, -1 to 15), 0 (IQR, -1 to 13), and 0 (-1 to 11) days (composed of 30%, 26%, and 33% mortality rates and 11.5, 9.5, and 6 median organ support-free days among survivors). The median adjusted odds ratio and bayesian probability of superiority were 1.43 (95% credible interval, 0.91-2.27) and 93% for fixed-dose hydrocortisone, respectively, and were 1.22 (95% credible interval, 0.76-1.94) and 80% for shock-dependent hydrocortisone compared with no hydrocortisone. Serious adverse events were reported in 4 (3%), 5 (3%), and 1 (1%) patients in the fixed-dose, shock-dependent, and no hydrocortisone groups, respectively. Conclusions and Relevance: Among patients with severe COVID-19, treatment with a 7-day fixed-dose course of hydrocortisone or shock-dependent dosing of hydrocortisone, compared with no hydrocortisone, resulted in 93% and 80% probabilities of superiority with regard to the odds of improvement in organ support-free days within 21 days. However, the trial was stopped early and no treatment strategy met prespecified criteria for statistical superiority, precluding definitive conclusions. Trial Registration: ClinicalTrials.gov Identifier: NCT02735707
Educomunicação e suas åreas de intervenção: Novos paradigmas para o diålogo intercultural
oai:omp.abpeducom.org.br:publicationFormat/1O material aqui divulgado representa, em essĂȘncia, a contribuição do VII Encontro Brasileiro de Educomunicação ao V Global MIL Week, da UNESCO, ocorrido na ECA/USP, entre 3 e 5 de novembro de 2016. Estamos diante de um conjunto de 104 papers executivos, com uma mĂ©dia de entre 7 e 10 pĂĄginas, cada um.
Com este rico e abundante material, chegamos ao sĂ©timo e-book publicado pela ABPEducom, em seus seis primeiros anos de existĂȘncia. A especificidade desta obra Ă© a de trazer as âĂreas de Intervençãoâ do campo da Educomunicação, colocando-as a serviço de uma meta essencial ao agir educomunicativo: o diĂĄlogo intercultural, trabalhado na linha do tema geral do evento internacional: Media and Information Literacy: New Paradigms for Intercultural Dialogue
Pervasive gaps in Amazonian ecological research
Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%â18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost
Pervasive gaps in Amazonian ecological research
Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%â18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost
COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study
Background:
The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19. We present relationships of age, sex, and nationality to presenting symptoms.
Methods:
International, prospective observational study of 60â109 hospitalized symptomatic patients with laboratory-confirmed COVID-19 recruited from 43 countries between 30 January and 3 August 2020. Logistic regression was performed to evaluate relationships of age and sex to published COVID-19 case definitions and the most commonly reported symptoms.
Results:
âTypicalâ symptoms of fever (69%), cough (68%) and shortness of breath (66%) were the most commonly reported. 92% of patients experienced at least one of these. Prevalence of typical symptoms was greatest in 30- to 60-year-olds (respectively 80, 79, 69%; at least one 95%). They were reported less frequently in children (â€â18 years: 69, 48, 23; 85%), older adults (â„â70 years: 61, 62, 65; 90%), and women (66, 66, 64; 90%; vs. men 71, 70, 67; 93%, each Pâ<â0.001). The most common atypical presentations under 60 years of age were nausea and vomiting and abdominal pain, and over 60 years was confusion. Regression models showed significant differences in symptoms with sex, age and country.
Interpretation:
This international collaboration has allowed us to report reliable symptom data from the largest cohort of patients admitted to hospital with COVID-19. Adults over 60 and children admitted to hospital with COVID-19 are less likely to present with typical symptoms. Nausea and vomiting are common atypical presentations under 30 years. Confusion is a frequent atypical presentation of COVID-19 in adults over 60 years. Women are less likely to experience typical symptoms than men
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