23 research outputs found

    Racist Babies? Resisting Whiteness in Parenting

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    Whiteness has evolved in the way that mostly white parents teach their children to embrace and normalize it. Whereas within the United States previously, white families employed explicitly racist tactics to maintain whiteness in their children, today white, neoliberal families have adapted their whiteness to be more implicit and socially acceptable. This chapter draws on literature and narrative inquiry to describe how whiteness is passed down, generation by generation. The author looks particularly at white, neoliberal, and color evasive families of today to deconstruct these myths. The author closes by offering strategies and examples for parents who want to raise critically conscious and socially just children and grow these traits within themselves as well

    Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

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    Genome-wide association studies (GWAS) have identified numerous common prostate cancer (PrCa) susceptibility loci. We have fine-mapped 64 GWAS regions known at the conclusion of the iCOGS study using large-scale genotyping and imputation in 25 723 PrCa cases and 26 274 controls of European ancestry. We detected evidence for multiple independent signals at 16 regions, 12 of which contained additional newly identified significant associations. A single signal comprising a spectrum of correlated variation was observed at 39 regions; 35 of which are now described by a novel more significantly associated lead SNP, while the originally reported variant remained as the lead SNP only in 4 regions. We also confirmed two association signals in Europeans that had been previously reported only in East-Asian GWAS. Based on statistical evidence and linkage disequilibrium (LD) structure, we have curated and narrowed down the list of the most likely candidate causal variants for each region. Functional annotation using data from ENCODE filtered for PrCa cell lines and eQTL analysis demonstrated significant enrichment for overlap with bio-features within this set. By incorporating the novel risk variants identified here alongside the refined data for existing association signals, we estimate that these loci now explain ∼38.9% of the familial relative risk of PrCa, an 8.9% improvement over the previously reported GWAS tag SNPs. This suggests that a significant fraction of the heritability of PrCa may have been hidden during the discovery phase of GWAS, in particular due to the presence of multiple independent signals within the same regio

    Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: A pooled analysis of 1018 population-based measurement studies with 88.6 million participants

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    © The Author(s) 2018. Background: Change in the prevalence of raised blood pressure could be due to both shifts in the entire distribution of blood pressure (representing the combined effects of public health interventions and secular trends) and changes in its high-blood-pressure tail (representing successful clinical interventions to control blood pressure in the hypertensive population). Our aim was to quantify the contributions of these two phenomena to the worldwide trends in the prevalence of raised blood pressure. Methods: We pooled 1018 population-based studies with blood pressure measurements on 88.6 million participants from 1985 to 2016. We first calculated mean systolic blood pressure (SBP), mean diastolic blood pressure (DBP) and prevalence of raised blood pressure by sex and 10-year age group from 20-29 years to 70-79 years in each study, taking into account complex survey design and survey sample weights, where relevant. We used a linear mixed effect model to quantify the association between (probittransformed) prevalence of raised blood pressure and age-group- and sex-specific mean blood pressure. We calculated the contributions of change in mean SBP and DBP, and of change in the prevalence-mean association, to the change in prevalence of raised blood pressure. Results: In 2005-16, at the same level of population mean SBP and DBP, men and women in South Asia and in Central Asia, the Middle East and North Africa would have the highest prevalence of raised blood pressure, and men and women in the highincome Asia Pacific and high-income Western regions would have the lowest. In most region-sex-age groups where the prevalence of raised blood pressure declined, one half or more of the decline was due to the decline in mean blood pressure. Where prevalence of raised blood pressure has increased, the change was entirely driven by increasing mean blood pressure, offset partly by the change in the prevalence-mean association. Conclusions: Change in mean blood pressure is the main driver of the worldwide change in the prevalence of raised blood pressure, but change in the high-blood-pressure tail of the distribution has also contributed to the change in prevalence, especially in older age groups

    Rising rural body-mass index is the main driver of the global obesity epidemic in adults

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    Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities(.)(1,2) This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity(3-6). Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean BMI segregated by place of residence (a rural or urban area) from 1985 to 2017. We show that, contrary to the dominant paradigm, more than 55% of the global rise in mean BMI from 1985 to 2017-and more than 80% in some low- and middle-income regions-was due to increases in BMI in rural areas. This large contribution stems from the fact that, with the exception of women in sub-Saharan Africa, BMI is increasing at the same rate or faster in rural areas than in cities in low- and middle-income regions. These trends have in turn resulted in a closing-and in some countries reversal-of the gap in BMI between urban and rural areas in low- and middle-income countries, especially for women. In high-income and industrialized countries, we noted a persistently higher rural BMI, especially for women. There is an urgent need for an integrated approach to rural nutrition that enhances financial and physical access to healthy foods, to avoid replacing the rural undernutrition disadvantage in poor countries with a more general malnutrition disadvantage that entails excessive consumption of low-quality calories.Peer reviewe

    Exposing the white avatar: projections, justifications, and the ever-evolving American racism

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    In the context of the United States, mainstream entertainment genres continue to recycle dominant racial ideologies typified by the perspectives of white men. American minstrelsy, literature, and film are key sites for whiteness to manifest itself in the design and projection of online personae via white avatars. These projections of whiteness also reify the US racial structure, one that subjects the perspectives of people of color to misrepresentation and further racial marginalization. This theoretical interpretative article employs Critical Race Theory (CRT) and Critical Whiteness Studies (CWS) to investigate how these projections of whiteness are historically rooted and have evolved in the post-racial era. Using popular virtual gaming and social media examples, this paper critically deconstructs how the creation of white personae via avatars maintains and justifies the hegemonic power of whiteness

    Exposing the white avatar: projections, justifications, and the ever-evolving American racism

    No full text
    © 2015 Taylor & Francis. In the context of the United States, mainstream entertainment genres continue to recycle dominant racial ideologies typified by the perspectives of white men. American minstrelsy, literature, and film are key sites for whiteness to manifest itself in the design and projection of online personae via white avatars. These projections of whiteness also reify the US racial structure, one that subjects the perspectives of people of color to misrepresentation and further racial marginalization. This theoretical interpretative article employs Critical Race Theory (CRT) and Critical Whiteness Studies (CWS) to investigate how these projections of whiteness are historically rooted and have evolved in the post-racial era. Using popular virtual gaming and social media examples, this paper critically deconstructs how the creation of white personae via avatars maintains and justifies the hegemonic power of whiteness
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