48 research outputs found

    A type reduction theory for systems with replicated components

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    The Parameterised Model Checking Problem asks whether an implementation Impl(t) satisfies a specification Spec(t) for all instantiations of parameter t. In general, t can determine numerous entities: the number of processes used in a network, the type of data, the capacities of buffers, etc. The main theme of this paper is automation of uniform verification of a subclass of PMCP with the parameter of the first kind, i.e. the number of processes in the network. We use CSP as our formalism. We present a type reduction theory, which, for a given verification problem, establishes a function \phi that maps all (sufficiently large) instantiations T of the parameter to some fixed type T^ and allows us to deduce that if Spec(T^) is refined by \phi(Impl(T)), then (subject to certain assumptions) Spec(T) is refined by Impl(T). The theory can be used in practice by combining it with a suitable abstraction method that produces a t-independent process Abstr that is refined by {\phi}(Impl(T)) for all sufficiently large T. Then, by testing (with a model checker) if the abstract model Abstr refines Spec(T^), we can deduce a positive answer to the original uniform verification problem. The type reduction theory relies on symbolic representation of process behaviour. We develop a symbolic operational semantics for CSP processes that satisfy certain normality requirements, and we provide a set of translation rules that allow us to concretise symbolic transition graphs. Based on this, we prove results that allow us to infer behaviours of a process instantiated with uncollapsed types from known behaviours of the same process instantiated with a reduced type. One of the main advantages of our symbolic operational semantics and the type reduction theory is their generality, which makes them applicable in a wide range of settings

    Rising rural body-mass index is the main driver of the global obesity epidemic in adults

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    Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities(.)(1,2) This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity(3-6). Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean BMI segregated by place of residence (a rural or urban area) from 1985 to 2017. We show that, contrary to the dominant paradigm, more than 55% of the global rise in mean BMI from 1985 to 2017-and more than 80% in some low- and middle-income regions-was due to increases in BMI in rural areas. This large contribution stems from the fact that, with the exception of women in sub-Saharan Africa, BMI is increasing at the same rate or faster in rural areas than in cities in low- and middle-income regions. These trends have in turn resulted in a closing-and in some countries reversal-of the gap in BMI between urban and rural areas in low- and middle-income countries, especially for women. In high-income and industrialized countries, we noted a persistently higher rural BMI, especially for women. There is an urgent need for an integrated approach to rural nutrition that enhances financial and physical access to healthy foods, to avoid replacing the rural undernutrition disadvantage in poor countries with a more general malnutrition disadvantage that entails excessive consumption of low-quality calories.Peer reviewe

    Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants

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    Summary Background Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents. Methods For this pooled analysis, we used a database of cardiometabolic risk factors collated by the Non-Communicable Disease Risk Factor Collaboration. We applied a Bayesian hierarchical model to estimate trends from 1985 to 2019 in mean height and mean BMI in 1-year age groups for ages 5–19 years. The model allowed for non-linear changes over time in mean height and mean BMI and for non-linear changes with age of children and adolescents, including periods of rapid growth during adolescence. Findings We pooled data from 2181 population-based studies, with measurements of height and weight in 65 million participants in 200 countries and territories. In 2019, we estimated a difference of 20 cm or higher in mean height of 19-year-old adolescents between countries with the tallest populations (the Netherlands, Montenegro, Estonia, and Bosnia and Herzegovina for boys; and the Netherlands, Montenegro, Denmark, and Iceland for girls) and those with the shortest populations (Timor-Leste, Laos, Solomon Islands, and Papua New Guinea for boys; and Guatemala, Bangladesh, Nepal, and Timor-Leste for girls). In the same year, the difference between the highest mean BMI (in Pacific island countries, Kuwait, Bahrain, The Bahamas, Chile, the USA, and New Zealand for both boys and girls and in South Africa for girls) and lowest mean BMI (in India, Bangladesh, Timor-Leste, Ethiopia, and Chad for boys and girls; and in Japan and Romania for girls) was approximately 9–10 kg/m2. In some countries, children aged 5 years started with healthier height or BMI than the global median and, in some cases, as healthy as the best performing countries, but they became progressively less healthy compared with their comparators as they grew older by not growing as tall (eg, boys in Austria and Barbados, and girls in Belgium and Puerto Rico) or gaining too much weight for their height (eg, girls and boys in Kuwait, Bahrain, Fiji, Jamaica, and Mexico; and girls in South Africa and New Zealand). In other countries, growing children overtook the height of their comparators (eg, Latvia, Czech Republic, Morocco, and Iran) or curbed their weight gain (eg, Italy, France, and Croatia) in late childhood and adolescence. When changes in both height and BMI were considered, girls in South Korea, Vietnam, Saudi Arabia, Turkey, and some central Asian countries (eg, Armenia and Azerbaijan), and boys in central and western Europe (eg, Portugal, Denmark, Poland, and Montenegro) had the healthiest changes in anthropometric status over the past 3·5 decades because, compared with children and adolescents in other countries, they had a much larger gain in height than they did in BMI. The unhealthiest changes—gaining too little height, too much weight for their height compared with children in other countries, or both—occurred in many countries in sub-Saharan Africa, New Zealand, and the USA for boys and girls; in Malaysia and some Pacific island nations for boys; and in Mexico for girls. Interpretation The height and BMI trajectories over age and time of school-aged children and adolescents are highly variable across countries, which indicates heterogeneous nutritional quality and lifelong health advantages and risks

    Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults

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    Background Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories. Methods We used data from 3663 population-based studies with 222 million participants that measured height and weight in representative samples of the general population. We used a Bayesian hierarchical model to estimate trends in the prevalence of different BMI categories, separately for adults (age ≥20 years) and school-aged children and adolescents (age 5–19 years), from 1990 to 2022 for 200 countries and territories. For adults, we report the individual and combined prevalence of underweight (BMI <18·5 kg/m2) and obesity (BMI ≥30 kg/m2). For schoolaged children and adolescents, we report thinness (BMI <2 SD below the median of the WHO growth reference) and obesity (BMI >2 SD above the median). Findings From 1990 to 2022, the combined prevalence of underweight and obesity in adults decreased in 11 countries (6%) for women and 17 (9%) for men with a posterior probability of at least 0·80 that the observed changes were true decreases. The combined prevalence increased in 162 countries (81%) for women and 140 countries (70%) for men with a posterior probability of at least 0·80. In 2022, the combined prevalence of underweight and obesity was highest in island nations in the Caribbean and Polynesia and Micronesia, and countries in the Middle East and north Africa. Obesity prevalence was higher than underweight with posterior probability of at least 0·80 in 177 countries (89%) for women and 145 (73%) for men in 2022, whereas the converse was true in 16 countries (8%) for women, and 39 (20%) for men. From 1990 to 2022, the combined prevalence of thinness and obesity decreased among girls in five countries (3%) and among boys in 15 countries (8%) with a posterior probability of at least 0·80, and increased among girls in 140 countries (70%) and boys in 137 countries (69%) with a posterior probability of at least 0·80. The countries with highest combined prevalence of thinness and obesity in school-aged children and adolescents in 2022 were in Polynesia and Micronesia and the Caribbean for both sexes, and Chile and Qatar for boys. Combined prevalence was also high in some countries in south Asia, such as India and Pakistan, where thinness remained prevalent despite having declined. In 2022, obesity in school-aged children and adolescents was more prevalent than thinness with a posterior probability of at least 0·80 among girls in 133 countries (67%) and boys in 125 countries (63%), whereas the converse was true in 35 countries (18%) and 42 countries (21%), respectively. In almost all countries for both adults and school-aged children and adolescents, the increases in double burden were driven by increases in obesity, and decreases in double burden by declining underweight or thinness. Interpretation The combined burden of underweight and obesity has increased in most countries, driven by an increase in obesity, while underweight and thinness remain prevalent in south Asia and parts of Africa. A healthy nutrition transition that enhances access to nutritious foods is needed to address the remaining burden of underweight while curbing and reversing the increase in obesit

    A century of trends in adult human height

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    Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight NCD Risk Factor Collaboration (NCD-RisC)

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    From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of underweight, obesity, and severe obesity in different regions using data from 2896 population-based studies with 187 million participants. Changes in the prevalence of underweight and total obesity, and to a lesser extent severe obesity, are largely driven by shifts in the distribution of BMI, with smaller contributions from changes in the shape of the distribution. In East and Southeast Asia and sub-Saharan Africa, the underweight tail of the BMI distribution was left behind as the distribution shifted. There is a need for policies that address all forms of malnutrition by making healthy foods accessible and affordable, while restricting unhealthy foods through fiscal and regulatory restrictions

    A multicriteria approach to different land use scenarios in the Western Carpathians with the SWAT model

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    Water erosion in mountainous areas is a major problem, especially on steep slopes exposed to intense precipitation. This paper presents the analysis of the topsoil loss using the SWAT (Soil and Water Assessment Tool) model. The SWAT model is a deterministic catchment model with a daily time step. It was designed to anticipate changes taking place in the catchment area, such as climate change and changes in land use and development, including the quantity and quality of water resources, soil erosion and agricultural production. In addition to hydrological and environmental aspects, the SWAT model is used to address socio-economic and demographic issues, such as water supply and food production. This program is integrated with QGIS software. The results were evaluated using the following statistical coefficients: determination (R2), Nash-Sutcliff model efficiency (NS), and percentage deviation index (PBIAS). An assessment of modelling results was made in terms of their variation according to different land cover scenarios. In the case of the scenario with no change in use, the average annual loss of topsoil (average upland sediment yield) was found to be 14.3 Mg∙ha-1. The maximum upland sediment yield was 94.6 Mg∙ha-1. On the other hand, there is an accumulation of soil material in the lower part of the catchment (in-stream sediment change), on average 13.27 Mg∙ha-1 per year

    Additive Contact Polarization of Nonferroelectric Polymers for Patterning of Multilevel Memory Elements

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    When a thin polymer film supported by a conductive substrate is contacted by and then separated from a micropatterned polymeric stamp, the so-called contact electrification creates electrical charges over the stamped regions. Simultaneously, image charges are induced in the conductive substrate. Together, the surface and image charges establish large fields within the film, in effect polarizing it. Upon consecutive stampings, the magnitudes of polarization add up, enabling imprinting of multilevel polarization patterns. Because the electric field is high only within the film but low across the Gaussian surface surrounding the film/substrate system, the discharge of surface charges is slow and the polarization patterns are relatively long-lived. These findings are significant since multilevel polarization states have, to date, been achieved only in ferroelectrics or some specialized polymers???the current method extends them to common polymers such as poly(methyl methacrylate), poly(vinyl pyrrolidone), or poly(vinyl acetate)
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