Governing a Digital Business Ecosystem: Lessons from ONE.MOTORING Portal

While the IT innovation topic has gathered significant research interests, the existing discourse on IT innovation is centered on internal organizational processes such as IT capability development and organizational learning rather than IT innovation networks as the primary means for achieving superior enterprise performance. This is an important topic because a networked perspective of IT-enabled innovation is a critical dimension for the dynamics of collaborative innovation in today’s networked economy. In particular, the development and implementation of a digital business ecosystem (DBE); a specific type of business ecosystem defined as an IT-enabled business network of entities with differing interests bound together in a collective whole, may hold the key to attaining superior enterprise performance in the context of organizations operating in complex business networks. Using a case study of ONE.MOTORING portal and adopting the theory of business ecosystems as an analytical lens, the objective of this study is to examine how are DBEs developed and governed? Our analysis identified three important lessons learnt that were instrumental in developing a DBE: institutionalizing ONE.MOTORING concept within business ecosystem; establishing connectivity and attaining network density and emphasizing value creation. We conclude with research and practice implications

Cross-reactive dengue human monoclonal antibody prevents severe pathologies and death from Zika virus infections

10.1172/jci.insight.92428JCI insight2

Use of nanomaterials in the pretreatment of water samples for environmental analysis

The challenge of providing clean drinking water is of enormous relevance in today’s human civilization, being essential for human consumption, but also for agriculture, livestock and several industrial applications. In addition to remediation strategies, the accurate monitoring of pollutants in water sup-plies, which most of the times are present at low concentrations, is a critical challenge. The usual low concentration of target analytes, the presence of in-terferents and the incompatibility of the sample matrix with instrumental techniques and detectors are the main reasons that renders sample preparation a relevant part of environmental monitoring strategies. The discovery and ap-plication of new nanomaterials allowed improvements on the pretreatment of water samples, with benefits in terms of speed, reliability and sensitivity in analysis. In this chapter, the use of nanomaterials in solid-phase extraction (SPE) protocols for water samples pretreatment for environmental monitoring is addressed. The most used nanomaterials, including metallic nanoparticles, metal organic frameworks, molecularly imprinted polymers, carbon-based nanomaterials, silica-based nanoparticles and nanocomposites are described, and their applications and advantages overviewed. Main gaps are identified and new directions on the field are suggested.publishe