CP violation and final state interactions in B --> K pi pi decays

Effects of CP violation and of final state interactions between pairs of pseudoscalar mesons are studied in three-body B+, B-, B0 and antiB0 decays into K pi pi. An alternative approach to the isobar model for three-body B decays is proposed. It is based on the QCD factorization approximation and the knowledge of the meson-meson form factors. Some phenomenological charming penguin amplitudes are needed to describe the branching fractions, direct CP asymmetries of the quasi-two-body B --> K*(892) pi and B --> K0*(1430) pi decays as well as the K pi effective mass and the helicity angle distributions. The experimental branching fractions for the B --> K0*(1430) pi decay, obtained by the Belle and BaBar collaborations using the isobar model, are larger than our predictions by about 52 per cent.Comment: 3 pages, contribution to International Europhysics Conference on High Energy Physics HEP 2007, Manchester (England), July 19-25, 200

The Impact of a Weighted Warmup on 1 - Mile Run Performance

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Effect of Light Brightness on Cycling Performance

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УПРАВЛІННЯ ЕКОНОМІЧНИМИ РИЗИКАМИ У МІЖНАРОДНОМУ МАРКЕТИНГУ

This paper presents a risk assessment model and economic securitymanagement model for components and subsystems of internationalmarketing. The development of the model is based on the principles and tools of the classical theory of risk management, adapted to the peculiarities of international marketing. Based on the review of the literature, an exhaustive list of risk factors was formed.The purpose of the article is to determine the impact of the level ofeconomic risk on international marketing activities. To achieve this goal,theoretical and practical aspects of business risk management andinternational marketing research, risk-oriented management practices areanalyzed. One of the objectives of the study is to consider the separate and synergistic impact of management practices on maintaining economicsecurity and risk management in international marketing.The main task is to assess the impact of economic risks on themeasures and approaches of international marketing, as a result of changes in which of the factors of international marketing activities would be able to meet the principles of economic security.The structure of risk analysis is used and a model for quantitativeassessment of risk factors is developed. The model can also be used toevaluate and select criteria in international marketing decisions.National differences require managers to formulate approaches due tothe conditions in each country. Differences typically require firms to makesignificant changes to their products and services.It is necessary to use methods of business marketing riskmanagement to improve competitive advantages. Coordinated application of business risk management leads to a synergistic effect in ensuring theinternational competitiveness of enterprises and the national economy. The use of a synergetic approach is an objectively determined process that depends on a number of factors of the international business environment, the evaluation and forecasting of which is an important task in marketing decisions making.В этой работе представлена модель оценки рисков и моделиуправления экономической безопасностью для компонентов и подсистеммаркетинга. Разработка модели базируется на принципах и инструментах классической теории управления рисками, приспособленной к особенностям маркетинга. На основе обстоятельного обзора литературы был сформирован исчерпывающий перечень факторов риска.Использована структура анализа рисков и разработана модель дляколичественной оценки факторов риска. Модель также может бытьиспользована для оценки и выбора критериальных подходов вмеждународной маркетинговой деятельности.У цій роботі представлена модель оцінки ризиків та моделі управління економічною безпекою для компонентів та підсистем міжнародного маркетингу. Розробка моделі базується на принципах та інструментах класичної теорії управління ризиками, пристосованої до особливостей міжнародного маркетингу. На основі ґрунтовного огляду літератури було сформовано вичерпний перелік факторів ризику. Використано структуру аналізу ризиків та розроблено модель для кількісної оцінки факторів ризику. Модель також може бути використана для оцінки та вибору критеріальних підходів в міжнародній маркетинговій діяльності

Scattering phase shift for relativistic exponential-type separable potentials

The J-matrix method of scattering is used to obtain analytic expressions for the phase shift of two classes of relativistic exponential-type separable potentials whose radial component is either of the general form r^(n-1)exp(-r) or r^(2n)exp(-r^2), where n = 0, 1, or 2. The rank of these separable potentials is n + 1. The nonrelativistic limit is obtained and shown to be identical to the nonrelativistic phase shift. An exact numerical evaluation for higher order potentials (n > 2) can also be obtained in a simple way as illustrated for the case n = 3.Comment: Accepted for publication in J. Phys. A, to appear in January 2002. Replaced with a more portable PDF versio

Combination of adenoviral virotherapy and temozolomide chemotherapy eradicates malignant glioma through autophagic and apoptotic cell death in vivo

Conditionally replicative adenoviruses (CRAds) represent a novel treatment strategy for malignant glioma. Recent studies suggest that the cytopathic effect elicited by these vectors is mediated through autophagy, a form of programmed cell death. Likewise, temozolomide (TMZ), a chemotherapeutic agent used for the treatment of malignant gliomas, also triggers autophagic cell death. In this study, we examined the potential to combine the two treatments in the setting of experimental glioma. In vitro, pretreatment with TMZ followed by CRAd-Surivin-pk7 enhanced cytotoxicity against a panel of glioma cell lines. Western blot analysis showed increased expression of BAX and p53, decreased expression of BCL2 and elevated level of APG5. Treatment with TMZ followed by CRAd-Survivin-pk7 (CRAd-S-pk7) led to a significant over-expression of autophagy markers, acidic vesicular organelles and light-chain 3 (LC3). These results were further evaluated in vivo, in which 90% of the mice with intracranial tumours were long-term survivors (>100 days) after treatment with TMZ and CRAd-S-pk7 (P<0.01). Analysis of tumours ex vivo showed expression of both LC3 and cleaved Caspase-3, proving that both autophagy and apoptosis are responsible for cell death in vivo. These results suggest that combination of chemovirotherapy offers a powerful tool against malignant glioma and should be further explored in the clinical setting

Biopolymers for Antitumor Implantable Drug Delivery Systems: Recent Advances and Future Outlook

In spite of remarkable improvements in cancer treatments and survivorship, cancer still remains as one of the major causes of death worldwide. Although current standards of care provide encouraging results, they still cause severe systemic toxicity and also fail in preventing recurrence of the disease. In order to address these issues, biomaterial-based implantable drug delivery systems (DDSs) have emerged as promising therapeutic platforms, which allow local administration of drugs directly to the tumor site. Owing to the unique properties of biopolymers, they have been used in a variety of ways to institute biodegradable implantable DDSs that exert precise spatiotemporal control over the release of therapeutic drug. Here, the most recent advances in biopolymer-based DDSs for suppressing tumor growth and preventing tumor recurrence are reviewed. Novel emerging biopolymers as well as cutting-edge polymeric microdevices deployed as implantable antitumor DDSs are discussed. Finally, a review of a new therapeutic modality within the field, which is based on implantable biopolymeric DDSs, is given

Does the lateral intercondylar ridge disappear in ACL deficient patients?

The aim of this study was to determine whether there is a difference in the presence of the lateral intercondylar ridge and the lateral bifurcate ridge between patients with sub-acute and chronic ACL injuries. We hypothesized that the ridges would be present less often with chronic ACL deficiency. Twenty-five patients with a chronic ACL injury were matched for age and gender to 25 patients with a sub-acute ACL injury. The lateral intercondylar ridge and lateral bifurcate ridge were scored as either present, absent, or indeterminate due to insufficient visualization by three blinded observers. The kappa for the three observers was .61 for the lateral intercondylar ridge and .58 for the lateral bifurcate ridge. The lateral intercondylar ridge was present in 88% of the sub-acute patients and 88% of the chronic patients. The lateral bifurcate ridge was present in 48% of the sub-acute and 48% of the chronic patients. This matched-pairs case–control study was unable to show a difference in the presence of the femoral bony ridges between patients with acute and chronic ACL injuries. The authors would suggest looking for the ridges as a landmark of the native ACL insertion site during ACL reconstruction in both acute and chronic ACL injuries

Measurement of the Bottom-Strange Meson Mixing Phase in the Full CDF Data Set

We report a measurement of the bottom-strange meson mixing phase \beta_s using the time evolution of B0_s -> J/\psi (->\mu+\mu-) \phi (-> K+ K-) decays in which the quark-flavor content of the bottom-strange meson is identified at production. This measurement uses the full data set of proton-antiproton collisions at sqrt(s)= 1.96 TeV collected by the Collider Detector experiment at the Fermilab Tevatron, corresponding to 9.6 fb-1 of integrated luminosity. We report confidence regions in the two-dimensional space of \beta_s and the B0_s decay-width difference \Delta\Gamma_s, and measure \beta_s in [-\pi/2, -1.51] U [-0.06, 0.30] U [1.26, \pi/2] at the 68% confidence level, in agreement with the standard model expectation. Assuming the standard model value of \beta_s, we also determine \Delta\Gamma_s = 0.068 +- 0.026 (stat) +- 0.009 (syst) ps-1 and the mean B0_s lifetime, \tau_s = 1.528 +- 0.019 (stat) +- 0.009 (syst) ps, which are consistent and competitive with determinations by other experiments.Comment: 8 pages, 2 figures, Phys. Rev. Lett 109, 171802 (2012