42 research outputs found
Midbrain organoids with an SNCA gene triplication model key features of synucleinopathy
- Author
- Abdian Narges
- Beitel Lenore K
- Cai Eddie
- Chen Carol X -Q
- Deneault Eric
- Durcan Thomas M
- Fon Edward A
- Karamchandani Jason
- Kunath Tilo
- Lépine Paula
- Mathur Meghna
- Maussion Gilles
- Mohamed Nguyen-Vi
- Nami Harris
- Nicouleau Michael
- Ramamurthy Janani
- Singh Dolt Karamjit
- Sirois Julien
- Soubannier Vincent
- Stratton Jo Anne
- Tabatabaei Mahdieh
- Thomas Rhalena A
- Wen Dingke
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 25/09/2021
- Field of study
A MicroRNA-7 Binding Site Polymorphism in HOXB5 Leads to Differential Gene Expression in Bladder Cancer
- Author
- A Feber
- A Giampaolo
- C Cillo
- C Cillo
- Chi-fai NG
- Eddie Chan
- EM Messing
- FJ Tsai
- HA Drabkin
- Hao Yu
- Hong Zeng
- Hui Huang
- Jian Huang
- Junhua Luo
- JW Lu
- L Huang
- Lorenzo Chiariotti
- M Cantile
- MV Volpe
- MV Volpe
- MV Volpe
- NH Gehring
- PJ Mishra
- Qingqing Cai
- R Hamamoto
- R Krumlauf
- R Morgan
- S Stein
- S Veerla
- S Winnik
- S Yu
- T Lin
- Tianxin Lin
- V Raman
- W Wang
- Wang He
- Wei Wang
- Weixi Deng
- WJ Gehring
- X Wang
- X Wu
- Y Wu
- Z Yu
- Publication venue
- Public Library of Science
- Publication date
- 29/06/2012
- Field of study
PURPOSE: To investigate the biological function of HOXB5 in human bladder cancer and explore whether the HOXB5 3'-UTR SNP (1010A/G), which is located within the microRNA-7 binding site, was correlated with clinical features of bladder cancer. METHODS: Expression of HOXB5 in 35 human bladder cancer tissues and 8 cell lines were examined using real-time PCR and immunohistochemistry. Next, we explored the biological function of HOXB5 in vitro using cell proliferation, migration and colony formation assays. Using bioinformatics, a SNP (1010A/G) was found located within the microRNA-7 binding site in the 3'-UTR of HOXB5. Real-time PCR was used to test HOXB5 expression affected by different alleles. Finally, multivariate logistic regression analysis was used to determine the relationship between SNP (1010A/G) frequency and clinical features in 391 cases. RESULTS: HOXB5 was frequently over-expressed both in bladder cancer tissues and cell lines. Inhibition of HOXB5 suppressed the oncogenic function of cancer cells. Next, we demonstrated that a SNP (1010A/G), located within the microRNA-7 binding site in the 3'-UTR of HOXB5, could affect HOXB5 expression in bladder cancer mainly by differential binding activity of microRNA-7 and SNP-related mRNA stability. Finally, we also showed the frequency of 1010G genotype was higher in cancer group compared to normal controls and correlated with the risk of high grade and high stage. CONCLUSION: HOXB5 is overexpressed in bladder cancer. A miRNA-binding SNP (1010A/G) located within 3'-UTR of HOXB5 is associated with gene expression and may be a promising prognostic factor for bladder cancer
Oxidative stress in children late after Kawasaki disease: relationship with carotid atherosclerosis and stiffness
- Author
- AH Slyper
- B Frei
- C Patterson
- Connie WH Woo
- D Behr-Roussel
- D Practico
- D Pratico
- Eddie WY Cheung
- FL Sung
- GN Levine
- H Cai
- H Senzaki
- HH Ting
- I Jialal
- I Jialal
- J Kals
- J Liao
- J Nourooz-Zadeh
- JD Morrow
- JL Cracowski
- JW Newburger
- K Yagi
- KA Tauber
- Karmin O
- M Hermes-Lima
- M Iemura
- N Madamanchik
- N Noto
- P Minuz
- Pak-cheong Chow
- PJ Kuhlencordt
- R Dhillon
- R Stocker
- R Stocker
- R Wu
- R Yamakawa
- Research Committee on Kawasaki Disease
- S Lavi
- S Ogawa
- S Rajagopalan
- S Wedgwood
- SK Venugopal
- Stephanie Armstrong
- T Hirai
- T Kawasaki
- T Sugimura
- U Rueckschloss
- U Rueckschloss
- U Singh
- U Solzbach
- X Peng
- X Yong
- Y Deng
- Y Higashi
- Y Mitani
- Y Mitani
- Yaw L Siow
- YF Cheung
- YF Cheung
- YF Cheung
- YF Cheung
- Yiu-fai Cheung
- Publication venue
- BioMed Central
- Publication date
- 01/01/2008
- Field of study
Background: Persistent arterial dysfunction in patients with a history of Kawasaki disease (KD) and an integral role of oxidative stress in the development of cardiovascular disease are increasingly recognized. We sought to test the hypothesis that oxidative stress is increased in KD patients and related to carotid atherosclerotic changes and stiffness. Methods: We compared the serum levels of oxidative stress biomarkers, carotid intima-media thickness (IMT), and carotid stiffness index among KD patients with coronary aneurysms (n = 32), those without coronary complications (n = 19), and controls (n = 32). Results: Compared with controls, patients with coronary aneurysms had significantly higher serum levels of malonaldehyde (2.62 ± 0.12 μM vs 2.22 ± 0.07 μM, p = 0.014) and hydroperoxides (26.50 ± 1.13 μM vs 22.50 ± 0.62 μM, p = 0.008). A linear trend of the magnitude of oxidative stress in relation to inflammatory damage was observed for malonaldehyde (p = 0.018) and hydroperoxides (p = 0.014) levels. Serum malonaldehyde and hydroperoxide levels correlated positively with carotid IMT (p < 0.001 and p = 0.034, respectively) and stiffness index (p = 0.001 and p = 0.021, respectively). Multiple linear regression analysis identified serum malonaldehyde level as a significant determinant of carotid IMT (β = 0.31, p = 0.006) and stiffness (β = 0.27, p = 0.008). Conclusion: Our findings suggestoxidative stress is increased in KD patients with coronary aneurysms and is associated with carotid intima-media thickening and stiffening. © 2008 Cheung et al; licensee BioMed Central Ltd.published_or_final_versio
Strong Carbon Features and a Red Early Color in the Underluminous Type Ia SN 2022xkq
- Author
- Anderson Joseph P.
- Andrews Jennifer E.
- Ashall Chris
- Auchettl Katie
- Baron Eddie
- Blondin Stéphane
- Bostroem K. Azalee
- Burns Christopher R.
- Cai Yongzhi
- Chen Ting-Wan
- Chomiuk Laura
- Coulter David A.
- Cross Dane
- Davis Kyle W.
- de Jaeger Thomas
- DerKacy James M.
- Desai Dhvanil D.
- Dimitriadis Georgios
- Do Aaron
- Dong Yize
- Evans Tycho Mera
- Farah Joseph R.
- Foley Ryan J.
- Galbany Lluís
- Gonzalez Estefania Padilla
- Gromadzki Mariusz
- Gutiérrez Claudia P.
- Haislip Joshua
- Hernández Jonay I. González
- Hinkle Jason T.
- Hoang Emily
- Hoeflich Peter
- Hoogendam Willem B.
- Hosseinzadeh Griffin
- Howell D. Andrew
- Hsiao Eric
- Huber Mark E.
- Janzen Daryl
- Jencson Jacob E.
- Jha Saurabh W.
- Kilpatrick Charles D.
- Kouprianov Vladimir
- Kumar Sahana
- Kwok Lindsey A.
- Larison Conor
- LeBaron Natalie
- Lu Jing
- Lundquist Michael J.
- Lundqvist Peter
- McCully Curtis
- Mehta Darshana
- Milne Peter
- Modjaz Maryam
- Morrell Nidia
- Müller-Bravo Tomás E.
- Newsome Megan
- Nicholl Matt
- Palau Cristina Jiménez
- Payne Anna V.
- Pearson Jeniveve
- Pellegrino Craig
- Phan Kim
- Pineda-García Jonathan
- Piro Anthony L.
- Piscarreta Lara
- Polin Abigail
- Reichart Daniel E.
- Retamal Nicolás Meza
- Rojas-Bravo César
- Ryder Stuart D.
- Salmaso Irene
- Sand David J.
- Saux Xavier Le
- Schwab Michaela
- Shahbandeh Melissa
- Shappee Benjamin J.
- Shrestha Manisha
- Siebert Matthew R.
- Smith Nathan
- Strader Jay
- Taggart Kirsty
- Terreran Giacomo
- Tinyanont Samaporn
- Tucker M. A.
- Valenti Stefano
- Valerin Giorgio
- Wyatt Samuel
- Young D. R.
- Publication venue
- Publication date
- 06/10/2023
- Field of study
We present optical, infrared, ultraviolet, and radio observations of SN
2022xkq, an underluminous fast-declining type Ia supernova (SN Ia) in NGC 1784
(D≈31 Mpc), from <1 to 180 days after explosion. The
high-cadence observations of SN 2022xkq, a photometrically transitional and
spectroscopically 91bg-like SN Ia, cover the first days and weeks following
explosion which are critical to distinguishing between explosion scenarios. The
early light curve of SN 2022xkq has a red early color and exhibits a flux
excess which is more prominent in redder bands; this is the first time such a
feature has been seen in a transitional/91bg-like SN Ia. We also present 92
optical and 19 near-infrared (NIR) spectra, beginning 0.4 days after explosion
in the optical and 2.6 days after explosion in the NIR. SN 2022xkq exhibits a
long-lived C I 1.0693 μm feature which persists until 5 days post-maximum.
We also detect C II λ6580 in the pre-maximum optical spectra. These
lines are evidence for unburnt carbon that is difficult to reconcile with the
double detonation of a sub-Chandrasekhar mass white dwarf. No existing
explosion model can fully explain the photometric and spectroscopic dataset of
SN 2022xkq, but the considerable breadth of the observations is ideal for
furthering our understanding of the processes which produce faint SNe Ia.Comment: 38 pages, 16 figures, accepted for publication in ApJ, the figure 15
input models and synthetic spectra are now available at
https://zenodo.org/record/837925
Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants
- Author
- Abarca-Gomez Leandra
- Abdeen Ziad A
- Abdrakhmanova Shynar
- Abu-Rmeileh Niveen M
- Acosta-Cazares Benjamin
- Adams Robert J
- Aekplakorn Wichai
- Afsana Kaosar
- Afzal Shoaib
- Agdeppa Imelda A
- Aghazadeh-Attari Javad
- Aguilar-Salinas Carlos A
- Agyemang Charles
- Ahmad Mohamad Hasnan
- Ahmad Noor Ani
- Ahmadi Ali
- Ahmadi Naser
- Ahmed Soheir H
- Ahrens Wolfgang
- Aitmurzaeva Gulmira
- Ajlouni Kamel
- Al Nsour Mohannad
- Al-Hazzaa Hazzaa M
- Al-Othman Amani Rashed
- Al-Raddadi Rajaa
- Alarouj Monira
- AlBuhairan Fadia
- AlDhukair Shahla
- Ali Mohamed M
- Alkandari Abdullah
- Alkerwi Ala'a
- Allin Kristine
- Alvarez-Pedrerol Mar
- Aly Eman
- Amarapurkar Deepak N
- Amiri Parisa
- Amougou Norbert
- Amouyel Philippe
- Andersen Lars Bo
- Anderssen Sigmund A
- Angquist Lars
- Anjana Ranjit Mohan
- Ansari-Moghaddam Alireza
- Aounallah-Skhiri Hajer
- Araujo Joana
- Ariansen Inger
- Aris Tahir
- Arku Raphael E
- Arlappa Nimmathota
- Aryal Krishna K
- Aspelund Thor
- Assah Felix K
- Assuncao Maria Cecilia F
- Aung May Soe
- Auvinen Juha
- Avdicova Maria
- Azevedo Ana
- Azimi-Nezhad Mohsen
- Azizi Fereidoun
- Azmin Mehrdad
- Babu Bontha V
- Baharudin Azli
- Bahijri Suhad
- Baker Jennifer L
- Balakrishna Nagalla
- Bamoshmoosh Mohamed
- Banach Maciej
- Bandosz Piotr
- Banegas Jose R
- Baran Joanna
- Barbagallo Carlo M
- Barcelo Alberto
- Barkat Amina
- Barros Aluisio JD
- Barros Mauro Virgilio Gomes
- Basit Abdul
- Bastos Joao Luiz D
- Bata Iqbal
- Batieha Anwar M
- Batista Rosangela L
- Battakova Zhamilya
- Batyrbek Assembekov
- Baur Louise A
- Beaglehole Robert
- Bebakar Wan Mohamad Wan
- Bel-Serrat Silvia
- Belavendra Antonisamy
- Ben Romdhane Habiba
- Benedics Judith
- Benet Mikhail
- Bennett James E
- Bennett James E
- Bentham James
- Bergh Ingunn Holden
- Berkinbayev Salim
- Bernabe-Ortiz Antonio
- Bernotiene Gailute
- Bettiol Heloisa
- Bezerra Jorge
- Bhagyalaxmi Aroor
- Bharadwaj Sumit
- Bhargava Santosh K
- Bhutta Zulfiqar A
- Bhutta Zulfiqar A
- Bi Hongsheng
- Bi Yufang
- Bia Daniel
- Bikbov Mukharram M
- Bista Bihungum
- Bixby Honor
- Bjelica Dusko J
- Bjerregaard Peter
- Bjertness Espen
- Bjertness Marius B
- Bjorkelund Cecilia
- Black Robert
- Bloch Katia V
- Blokstra Anneke
- Bo Simona
- Bobak Martin
- Boddy Lynne M
- Boehm Bernhard O
- Boeing Heiner
- Boggia Jose G
- Bogova Elena
- Boissonnet Carlos P
- Bojesen Stig E
- Boker Lital Keinan
- Bonaccio Marialaura
- Bongard Vanina
- Bonilla-Vargas Alice
- Bopp Matthias
- Borghs Herman
- Bovet Pascal
- Braeckevelt Lien
- Braeckman Lutgart
- Bragt Marjolijn CE
- Brajkovich Imperia
- Branca Francesco
- Braunerova Radka Taxova
- Breckenkamp Juergen
- Breda Joao
- Brenner Hermann
- Brewster Lizzy M
- Brian Garry R
- Brinduse Lacramioara
- Brophy Sinead
- Bruno Graziella
- Bueno-de-Mesquita H Bas
- Bugge Anna
- Buoncristiano Marta
- Burazeri Genc
- Burns Con
- Cacciottolo Joseph
- Cadena Leticia Hernandez
- Cai Hui
- Cama Tilema
- Cameron Christine
- Camolas Jose
- Can Gunay
- Candido Ana Paula C
- Canete Felicia
- Capanzana Mario V
- Capkova Nadezda
- Capuano Eduardo
- Capuano Vincenzo
- Cardol Marloes
- Cardoso Viviane C
- Carlsson Axel C
- Carmuega Esteban
- Carrillo-Larco Rodrigo M
- Carvalho Joana
- Casajus Jose A
- Casanueva Felipe F
- Celikcan Ertugrul
- Censi Laura
- Cervantes-Loaiza Marvin
- Cesar Juraci A
- Chamukuttan Snehalatha
- Chan Angelique W
- Chan Queenie
- Chaturvedi Himanshu K
- Chaturvedi Nish
- Chen Chien-Jen
- Chen Fangfang
- Chen Huashuai
- Chen Shuohua
- Chen Zhengming
- Cheng Ching-Yu
- Cheraghian Bahman
- Chetrit Angela
- Chikova-Iscener Ekaterina
- Chinh Nguyen Huu
- Chiolero Arnaud
- Chiou Shu-Ti
- Chirita-Emandi Adela
- Chirita-Emandi Adela
- Chirlaque Maria-Dolores
- Cho Belong
- Christensen Kaare
- Christofaro Diego G
- Chudek Jerzy
- Cifkova Renata
- Cilia Michelle
- Cinteza Eliza
- Cisneros Julio Zuniga
- Claessens Frank
- Clarke Janine
- Clays Els
- Cohen Emmanuel
- Concin Hans
- Confortin Susana C
- Cooper Cyrus
- Coppinger Tara C
- Corpeleijn Eva
- Costanzo Simona
- Cottel Dominique
- Cowan Melanie J
- Cowell Chris
- Craig Cora L
- Crampin Amelia C
- Crujeiras Ana B
- Csilla Semanova
- Cucu Alexandra M
- Cui Liufu
- Cureau Felipe V
- D'Arrigo Graziella
- d'Orsi Eleonora
- da Silva Bruna Goncalves Cordeiro
- Dacica Liliana
- Dallongeville Jean
- Damasceno Albertino
- Damsgaard Camilla T
- Danaei Goodarz
- Danaei Goodarz
- Dankner Rachel
- Dantoft Thomas M
- Dasgupta Parasmani
- Dastgiri Saeed
- Dauchet Luc
- Davletov Kairat
- De Backer Guy
- De Bacquer Dirk
- de Gaetano Giovanni
- De Henauw Stefaan
- de Leon Antonio Cabrera
- de Oliveira Paula Duarte
- de Paiva Karina Mary
- De Ridder David
- De Ridder Karin
- de Rooij Susanne R
- De Smedt Delphine
- de Souza Rildo
- de Wit Tobias F Rinke
- Deepa Mohan
- Deev Alexander D
- DeGennaro Vincent
- Dehghan Abbas
- Delisle Helene
- Delpeuch Francis
- Demarest Stefaan
- Dennison Elaine
- Deren Katarzyna
- Deschamps Valerie
- Dhana Klodian
- Dhimal Meghnath
- Di Castelnuovo Augusto F
- Di Cesare Mariachiara
- Dias-da-Costa Juvenal Soares
- Diaz Alejandro
- Diaz-Sanchez Maria Elena
- Dika Zivka
- Djalalinia Shirin
- Djordjic Visnja
- Do Ha TP
- Dobson Annette J
- Donati Maria Benedetta
- Donfrancesco Chiara
- Donoso Silvana P
- Doring Angela
- Dorobantu Maria
- Dorosty Ahmad Reza
- Doua Kouamelan
- Drygas Wojciech
- Duan Jia Li
- Duante Charmaine A
- Duboz Priscilla
- Duda Rosemary B
- Duleva Vesselka
- Dulskiene Virginija
- Dumith Samuel C
- Dushpanova Anar
- Dzerve Vilnis
- Dziankowska-Zaborszczyk Elzbieta
- Eddie Ricky
- Eftekhar Ebrahim
- Egbagbe Eruke E
- Eggertsen Robert
- Eghtesad Sareh
- Eiben Gabriele
- Ekelund Ulf
- El Ati Jalila
- El-Khateeb Mohammad
- Eldemire-Shearer Denise
- Eliasen Marie
- Elliott Paul
- Engle-Stone Reina
- Enguerran Macia
- Erasmus Rajiv T
- Erbel Raimund
- Erem Cihangir
- Eriksen Louise
- Eriksson Johan G
- Escobedo-de la Pena Jorge
- Eslami Saeid
- Esmaeili Ali
- Evans Alun
- Ezzati Majid
- Faeh David
- Fakhretdinova Albina A
- Fall Caroline H
- Faramarzi Elnaz
- Farjam Mojtaba
- Farzadfar Farshad
- Fattahi Mohammad Reza
- Fawwad Asher
- Felix-Redondo Francisco J
- Ferguson Trevor S
- Fernandes Romulo A
- Fernandez-Berges Daniel
- Ferrante Daniel
- Ferrao Thomas
- Ferrari Marika
- Ferrario Marco M
- Ferreccio Catterina
- Ferrer Eldridge
- Ferrieres Jean
- Figueiro Thamara Hubler
- Fijalkowska Anna
- Fink Gunther
- Fischer Krista
- Foger Bernhard
- Foo Leng Huat
- Forsner Maria
- Fouad Heba M
- Francis Damian K
- Franco Maria do Carmo
- Franco Oscar H
- Frikke-Schmidt Ruth
- Frontera Guillermo
- Fuchs Flavio D
- Fuchs Sandra C
- Fujiati Isti I
- Fujita Yuki
- Fumihiko Matsuda
- Furusawa Takuro
- Gaciong Zbigniew
- Gafencu Mihai
- Galbarczyk Andrzej
- Galenkamp Henrike
- Galeone Daniela
- Galfo Myriam
- Galvano Fabio
- Gao Jingli
- Garba Jamila Abubakar
- Garcia-de-la-Hera Manoli
- Garcia-Solano Marta
- Gareta Dickman
- Garnett Sarah P
- Gaspoz Jean-Michel
- Gasull Magda
- Gaya Adroaldo Cesar Araujo
- Gaya Anelise Reis
- Gazzinelli Andrea
- Gehring Ulrike
- Geiger Harald
- Geleijnse Johanna M
- Ghaffar Suhaila Abdul
- Ghanbari Ali
- Ghasemi Erfan
- Gheorghe-Fronea Oana-Florentina
- Giampaoli Simona
- Gianfagna Francesco
- Gill Tiffany K
- Giovannelli Jonathan
- Gironella Glen
- Giwercman Aleksander
- Gkiouras Konstantinos
- Godos Justyna
- Gogen Sibel
- Goldsmith Rebecca A
- Goltzman David
- Gomez Santiago F
- Gomula Aleksandra
- Goncalves Helen
- Gonzalez Angel R
- Gonzalez-Chica David A
- Gonzalez-Gross Marcela
- Gonzalez-Leon Margot
- Gonzalez-Rivas Juan P
- Gonzalez-Villalpando Clicerio
- Gonzalez-Villalpando Maria-Elena
- Gottrand Frederic
- Graca Antonio Pedro
- Graff-Iversen Sidsel
- Grafnetter Dusan
- Grajda Aneta
- Grammatikopoulou Maria G
- Gregg Edward W
- Gregor Ronald D
- Grodzicki Tomasz
- Groholt Else Karin
- Grontved Anders
- Grosso Giuseppe
- Gruden Gabriella
- Gu Dongfeng
- Gualdi-Russo Emanuela
- Guallar-Castillon Pilar
- Gualtieri Andrea
- Gudmundsson Elias F
- Gudnason Vilmundur
- Guerrero Ramiro
- Guessous Idris
- Guimaraes Andre L
- Gulliford Martin C
- Gunnlaugsdottir Johanna
- Gunter Marc J
- Guo Xiu-Hua
- Guo Yin
- Gupta Prakash C
- Gupta Rajeev
- Gureje Oye
- Gurzkowska Beata
- Gutierrez Laura
- Gutierrez-Gonzalez Enrique
- Gutzwiller Felix
- Ha Seongjun
- Hadaegh Farzad
- Hadjigeorgiou Charalambos A
- Haghshenas Rosa
- Hakimi Hamid
- Halkjaer Jytte
- Hambleton Ian R
- Hamzeh Behrooz
- Hange Dominique
- Hanif Abu AM
- Hantunen Sari
- Hashemi-Shahri Seyed Mohammad
- Hassapidou Maria
- Hata Jun
- Haugsgjerd Teresa
- Hayes Alison J
- He Jiang
- He Yuan
- He Yuna
- Heidinger-Felso Regina
- Heinen Mirjam
- Hejgaard Tatjana
- Hendriks Marleen Elisabeth
- Henrique Rafael dos Santos
- Henriques Ana
- Herrala Sauli
- Herrera Victor M
- Herter-Aeberli Isabelle
- Heshmat Ramin
- Hill Allan G
- Ho Sai Yin
- Ho Suzanne C
- Hoang Van Minh
- Hobbs Michael
- Hofman Albert
- Holdsworth Michelle
- Homayounfar Reza
- Homs Clara
- Hopman Wilma M
- Horimoto Andrea RVR
- Hormiga Claudia M
- Horta Bernardo L
- Houti Leila
- Howitt Christina
- Htet Aung Soe
- Htike Maung Maung Than
- Hu Yonghua
- Huerta Jose Maria
- Huhtaniemi Ilpo Tapani
- Husseini Abdullatif
- Huybrechts Inge
- Hwalla Nahla
- Hyska Jolanda
- Iacoviello Licia
- Ibarluzea Jesus M
- Ibrahim Mohsen M
- Ikeda Nayu
- Ikram M Arfan
- Ioannidou Eliza Markidou
- Iotova Violeta
- Irazola Vilma E
- Ishida Takafumi
- Islam Muhammad
- Islam Sheikh Mohammed Shariful
- Iurilli Maria LC
- Iwasaki Masanori
- Jackson Rod T
- Jacobs Jeremy M
- Jaddou Hashem Y
- Jafar Tazeen
- James Kenneth
- Jamil Kazi M
- Jamrozik Konrad
- Janszky Imre
- Janus Edward
- Jarani Juel
- Jarvelin Marjo-Riitta
- Jasienska Grazyna
- Jelakovic Ana
- Jelakovic Bojan
- Jennings Garry
- Jerome Charles Sossa
- Jha Anjani Kumar
- Jiang Chao Qiang
- Jimenez Ramon O
- Jockel Karl-Heinz
- Joffres Michel
- Johansson Mattias
- Jokelainen Jari J
- Jonas Jost B
- Jonsson Kenisha Russell
- Jorgensen Maja Baeksgaard
- Jorgensen Torben
- Joshi Pradeep
- Joukar Farahnaz
- Jovic Dragana P
- Jozwiak Jacek J
- Junior Wanderley
- Juolevi Anne
- Jurak Gregor
- Juresa Vesna
- Kaaks Rudolf
- Kaducu Felix O
- Kafatos Anthony
- Kajantie Eero O
- Kalmatayeva Zhanna
- Kalter-Leibovici Ofra
- Kameli Yves
- Kanala Kodanda R
- Kannan Srinivasan
- Kapantais Efthymios
- Karki Khem B
- Katibeh Marzieh
- Katz Joanne
- Katzmarzyk Peter T
- Kauhanen Jussi
- Kaur Prabhdeep
- Kavousi Maryam
- Kazakbaeva Gyulli M
- Keil Ulrich
- Keinanen-Kiukaanniemi Sirkka
- Kelishadi Roya
- Kelleher Cecily
- Kemper Han CG
- Kengne Andre P
- Kengne Andre P
- Keramati Maryam
- Kerimkulova Alina
- Kersting Mathilde
- Key Timothy
- Khader Yousef Saleh
- Khalili Davood
- Khang Young-Ho
- Khang Young-Ho
- Khanh Le Nguyen Bao
- Khaw Kay-Tee
- Kheiri Bahareh
- Kheradmand Motahareh
- Khosravi Alireza
- Khouw Ilse MSL
- Khuong Quynh Long
- Kiechl Stefan
- Kiechl-Kohlendorfer Ursula
- Killewo Japhet
- Kim Dong Wook
- Kim Hyeon Chang
- Kim Jeongseon
- Kindblom Jenny M
- Klakk Heidi
- Klimek Magdalena
- Klimont Jeannette
- Klumbiene Jurate
- Knoflach Michael
- Koirala Bhawesh
- Kolle Elin
- Kolsteren Patrick
- Konig Jurgen
- Korpelainen Raija
- Korrovits Paul
- Korzycka Magdalena
- Kos Jelena
- Koskinen Seppo
- Kouda Katsuyasu
- Kovacs Viktoria A
- Kowlessur Sudhir
- Koziel Slawomir
- Kratzer Wolfgang
- Kriemler Susi
- Kristensen Peter Lund
- Krokstad Steiner
- Kromhout Daan
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- Wannamethee S Goya
- Wareham Nicholas
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- Wedderkopp Niels
- Weerasekera Deepa
- Weghuber Daniel
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- Wong-McClure Roy A
- Woo Jean
- Woodward Mark
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- Xu Haiquan
- Xu Liang
- Yaacob Nor Azwany
- Yamborisut Uruwan
- Yan Weili
- Yang Ling
- Yang Xiaoguang
- Yang Yang
- Yardim Nazan
- Yaseri Mehdi
- Yasuharu Tabara
- Ye Xingwang
- Yiallouros Panayiotis K
- Yoosefi Moein
- Yoshihara Akihiro
- You Qi Sheng
- You San-Lin
- Younger-Coleman Novie O
- Yusof Safiah Md
- Yusoff Ahmad Faudzi
- Yusoff Muhammad Fadhli Mohd
- Zaccagni Luciana
- Zafiropulos Vassilis
- Zainuddin Ahmad A
- Zainuddin Ahmad A
- Zakavi Seyed Rasoul
- Zamani Farhad
- Zambon Sabina
- Zampelas Antonis
- Zamrazilova Hana
- Zapata Maria Elisa
- Zargar Abdul Hamid
- Zaw Ko Ko
- Zdrojewski Tomasz
- Zeng Yi
- Zhang Luxia
- Zhang Zhen-Yu
- Zhao Dong
- Zhao Ming-Hui
- Zhao Wenhua
- Zhen Shiqi
- Zheng Wei
- Zheng Yingfeng
- Zholdin Bekbolat
- Zhou Bin
- Zhou Maigeng
- Zhu Dan
- Zocalo Yanina
- Zuziak Monika
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2020
- Field of study
Summary Background Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents. Methods For this pooled analysis, we used a database of cardiometabolic risk factors collated by the Non-Communicable Disease Risk Factor Collaboration. We applied a Bayesian hierarchical model to estimate trends from 1985 to 2019 in mean height and mean BMI in 1-year age groups for ages 5–19 years. The model allowed for non-linear changes over time in mean height and mean BMI and for non-linear changes with age of children and adolescents, including periods of rapid growth during adolescence. Findings We pooled data from 2181 population-based studies, with measurements of height and weight in 65 million participants in 200 countries and territories. In 2019, we estimated a difference of 20 cm or higher in mean height of 19-year-old adolescents between countries with the tallest populations (the Netherlands, Montenegro, Estonia, and Bosnia and Herzegovina for boys; and the Netherlands, Montenegro, Denmark, and Iceland for girls) and those with the shortest populations (Timor-Leste, Laos, Solomon Islands, and Papua New Guinea for boys; and Guatemala, Bangladesh, Nepal, and Timor-Leste for girls). In the same year, the difference between the highest mean BMI (in Pacific island countries, Kuwait, Bahrain, The Bahamas, Chile, the USA, and New Zealand for both boys and girls and in South Africa for girls) and lowest mean BMI (in India, Bangladesh, Timor-Leste, Ethiopia, and Chad for boys and girls; and in Japan and Romania for girls) was approximately 9–10 kg/m2. In some countries, children aged 5 years started with healthier height or BMI than the global median and, in some cases, as healthy as the best performing countries, but they became progressively less healthy compared with their comparators as they grew older by not growing as tall (eg, boys in Austria and Barbados, and girls in Belgium and Puerto Rico) or gaining too much weight for their height (eg, girls and boys in Kuwait, Bahrain, Fiji, Jamaica, and Mexico; and girls in South Africa and New Zealand). In other countries, growing children overtook the height of their comparators (eg, Latvia, Czech Republic, Morocco, and Iran) or curbed their weight gain (eg, Italy, France, and Croatia) in late childhood and adolescence. When changes in both height and BMI were considered, girls in South Korea, Vietnam, Saudi Arabia, Turkey, and some central Asian countries (eg, Armenia and Azerbaijan), and boys in central and western Europe (eg, Portugal, Denmark, Poland, and Montenegro) had the healthiest changes in anthropometric status over the past 3·5 decades because, compared with children and adolescents in other countries, they had a much larger gain in height than they did in BMI. The unhealthiest changes—gaining too little height, too much weight for their height compared with children in other countries, or both—occurred in many countries in sub-Saharan Africa, New Zealand, and the USA for boys and girls; in Malaysia and some Pacific island nations for boys; and in Mexico for girls. Interpretation The height and BMI trajectories over age and time of school-aged children and adolescents are highly variable across countries, which indicates heterogeneous nutritional quality and lifelong health advantages and risks
Rising rural body-mass index is the main driver of the global obesity epidemic in adults
- Author
- Abarca-Gomez Leandra
- Abdeen Ziad A.
- Abdrakhmanova Shynar
- Abu-Rmeileh Niveen M.
- Acosta-Cazares Benjamin
- Adams Robert J.
- Aekplakorn Wichai
- Afsana Kaosar
- Agdeppa Imelda A.
- Aguilar-Salinas Carlos A.
- Agyemang Charles
- Ahmad Mohamad Hasnan
- Ahmad Noor Ani
- Ahmadi Naser
- Ahmadvand Alireza
- Ahrens Wolfgang
- Ajlouni Kamel
- Al Nsour Mohannad
- Al-Hazzaa Hazzaa M.
- Al-Othman Amani Rashed
- Al-Raddadi Rajaa
- AlBuhairan Fadia
- AlDhukair Shahla
- Ali Mohamed M.
- Ali Osman
- Alkerwi Ala'a
- Alvarez-Pedrerol Mar
- Aly Eman
- Amarapurkar Deepak N.
- Amouyel Philippe
- Amuzu Antoinette
- Anderssen Sigmund A.
- Angquist Lars H.
- Anjana Ranjit Mohan
- Ansari-Moghaddam Alireza
- Anselmo Olinto Maria Teresa
- Aounallah-Skhiri Hajer
- Araujo Joana
- Ariansen Inger
- Aris Tahir
- Arku Raphael E.
- Arlappa Nimmathota
- Aryal Krishna K.
- Aspelund Thor
- Assah Felix K.
- Assuncao Maria Cecilia F.
- Aung May Soe
- Auvinen Juha
- Avdicova Maria
- Azevedo Ana
- Azizi Fereidoun
- Azmin Mehrdad
- Babu Bontha V.
- Baharudin Azli
- Bahijri Suhad
- Baker Jennifer L.
- Balakrishna Nagalla
- Bamoshmoosh Mohamed
- Banach Maciej
- Bandosz Piotr
- Banegas Jose R.
- Barbagallo Carlo M.
- Barcelo Alberto
- Barkat Amina
- Barros Aluisio J. D.
- Barros Mauro V. G.
- Bata Iqbal
- Batieha Anwar M.
- Batista Rosangela L.
- Battakova Zhamilya
- Batyrbek Assembekov
- Baur Louise A.
- Beaglehole Robert
- Bebakar Wan Mohamad Wan
- Bel-Serrat Silvia
- Ben Romdhane Habiba
- Benedics Judith
- Benet Mikhail
- Bennett James E.
- Bentham James
- Berkinbayev Salim
- Bernabe-Ortiz Antonio
- Bernotiene Gailute
- Bettiol Heloisa
- Bhagyalaxmi Aroor
- Bharadwaj Sumit
- Bhargava Santosh K.
- Bhutta Zulfiqar A.
- Bi Hongsheng
- Bi Yufang
- Biehl Anna
- Bikbov Mukharram
- Bista Bihungum
- Bixby Honor
- Bjelica Dusko J.
- Bjerregaard Peter
- Bjertness Espen
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- Tzourio Christophe
- Ueda Peter
- Ugel Eunice E.
- Ukoli Flora A. M.
- Ulmer Hanno
- Unal Belgin
- Uusitalo Hannu M. T.
- Vaitkeviciute Justina
- Valdivia Gonzalo
- Vale Susana
- Valvi Damaskini
- van der Schouw Yvonne T.
- Van Herck Koen
- van Rossem Lenie
- Van Schoor Natasja M.
- van Valkengoed Irene G. M.
- Vanderschueren Dirk
- Vanuzzo Diego
- Varela-Moreiras Gregorio
- Varona-Perez Patricia
- Vatten Lars
- Vega Tomas
- Veidebaum Toomas
- Velasquez-Melendez Gustavo
- Velika Biruta
- Veronesi Giovanni
- Verschuren W. M. Monique
- Victora Cesar G.
- Viegi Giovanni
- Viet Lucie
- Vineis Paolo
- Vioque Jesus
- Virtanen Jyrki K.
- Visser Marjolein
- Visvikis-Siest Sophie
- Viswanathan Bharathi
- Vlasoff Tiina
- Vollenweider Peter
- Volzke Henry
- Voutilainen Ari
- Voutilainen Sari
- Vrijheid Martine
- Vrijkotte Tanja G. M.
- Vrkic Tajana Zeljkovic
- Wade Alisha N.
- Wagner Aline
- Waldhoer Thomas
- Walton Janette
- Wanderley Rildo S., Jr.
- Wang Ming-Dong
- Wang Qian
- Wang Xiangjun
- Wang Ya Xing
- Wang Ying-Wei
- Wannamethee S. Goya
- Wareham Nicholas
- Weber Adelheid
- Weerasekera Deepa
- Weghuber Daniel
- Wei Wenbin
- Whincup Peter H.
- Widhalm Kurt
- Widyahening Indah S.
- Wiecek Andrzej
- Wijga Alet H.
- Wilks Rainford J.
- Willeit Johann
- Willeit Peter
- Wilsgaard Tom
- Wojtyniak Bogdan
- Wong Jyh Eiin
- Wong Norazizah Ibrahim
- Wong Tien Yin
- Wong-McClure Roy A.
- Woo Jean
- Woodward Mark
- Wu Frederick C.
- Wu Jianfeng
- Wu Shouling
- Xu Haiquan
- Xu Liang
- Yamborisut Uruwan
- Yan Weili
- Yang Ling
- Yang Xiaoguang
- Yang Yang
- Yardim Nazan
- Yaseri Mehdi
- Ye Xingwang
- Yiallouros Panayiotis K.
- Yngve Agneta
- Yoosefi Moein
- Yoshihara Akihiro
- You Qi Sheng
- You San-Lin
- Younger-Coleman Novie O.
- Yusof Safiah Md
- Yusoff Ahmad Faudzi
- Yusoff Muhammad Fadhli Mohd
- Zaccagni Luciana
- Zafiropulos Vassilis
- Zainuddin Ahmad A.
- Zamani Farhad
- Zambon Sabina
- Zampelas Antonis
- Zamrazilova Hana
- Zapata Maria Elisa
- Zaw Ko Ko
- Zdrojewski Tomasz
- Zeng Yi
- Zhao Dong
- Zhao Wenhua
- Zheng Wei
- Zheng Yingfeng
- Zholdin Bekbolat
- Zhou Bin
- Zhou Maigeng
- Zhu Dan
- Zhussupov Baurzhan
- Zimmermann Esther
- Zuniga Cisneros Julio
- Publication venue
- Publication date
- 01/01/2019
- Field of study
Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities(.)(1,2) This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity(3-6). Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean BMI segregated by place of residence (a rural or urban area) from 1985 to 2017. We show that, contrary to the dominant paradigm, more than 55% of the global rise in mean BMI from 1985 to 2017-and more than 80% in some low- and middle-income regions-was due to increases in BMI in rural areas. This large contribution stems from the fact that, with the exception of women in sub-Saharan Africa, BMI is increasing at the same rate or faster in rural areas than in cities in low- and middle-income regions. These trends have in turn resulted in a closing-and in some countries reversal-of the gap in BMI between urban and rural areas in low- and middle-income countries, especially for women. In high-income and industrialized countries, we noted a persistently higher rural BMI, especially for women. There is an urgent need for an integrated approach to rural nutrition that enhances financial and physical access to healthy foods, to avoid replacing the rural undernutrition disadvantage in poor countries with a more general malnutrition disadvantage that entails excessive consumption of low-quality calories.Peer reviewe
Diminishing benefits of urban living for children and adolescents’ growth and development
- Author
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- Abdeen Z. A.
- Abdrakhmanova S.
- Abdul Rahim H. F.
- Abdurrahmonova Z.
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- Adam I.
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- Publication venue
- Publication date
- 01/01/2023
- Field of study
Optimal growth and development in childhood and adolescence is crucial for lifelong health and well-being1–6. Here we used data from 2,325 population-based studies, with measurements of height and weight from 71 million participants, to report the height and body-mass index (BMI) of children and adolescents aged 5–19 years on the basis of rural and urban place of residence in 200 countries and territories from 1990 to 2020. In 1990, children and adolescents residing in cities were taller than their rural counterparts in all but a few high-income countries. By 2020, the urban height advantage became smaller in most countries, and in many high-income western countries it reversed into a small urban-based disadvantage. The exception was for boys in most countries in sub-Saharan Africa and in some countries in Oceania, south Asia and the region of central Asia, Middle East and north Africa. In these countries, successive cohorts of boys from rural places either did not gain height or possibly became shorter, and hence fell further behind their urban peers. The difference between the age-standardized mean BMI of children in urban and rural areas was <1.1 kg m–2 in the vast majority of countries. Within this small range, BMI increased slightly more in cities than in rural areas, except in south Asia, sub-Saharan Africa and some countries in central and eastern Europe. Our results show that in much of the world, the growth and developmental advantages of living in cities have diminished in the twenty-first century, whereas in much of sub-Saharan Africa they have amplified
Finishing the euchromatic sequence of the human genome
- Author
- . Haifeng
- . Magner
- . Yin
- Abbott Scott
- Abbott-Ozersky Amanda
- Abdellah Zahra
- Abouelleil Amr
- Abrajano Anne
- Adachi Tamami
- Adam Catherine
- Adams Charles Q.
- Adamson Aaron
- Adekoya Emmanuel
- Adio-Oduola Babajide
- Aerts Andrea
- Aggarwal Arun
- Ahmadi Alireza
- Ahmed Shahana
- Aimable Matthew
- Ainscough Rachael
- Ait-Zahra Mostafa
- Aizu Tomoyuki
- Alcivare Dana
- Alegria Michelle
- Ali Alla
- Ali Johar
- Allegria-hartmann Michelle
- Alleman Jennifer
- Allen Carlana C.
- Allen Heather
- Allen Nicole R.
- Allen Susan
- Allen Thaddeus
- Almeida Jeff
- Almond Claire
- Alsbrooks Stephen L.
- Altherr Michael R.
- Amaratunge Harshinie C.
- Ambler Andrew
- Ambrose Karen
- Ambrose Kerrie
- Amemiya Chris
- Amico-Keller Gina
- Amin Amita G.
- Anderson Mechele
- Anderson Scott
- Anderson Scott
- Andora Janice
- Andredesz Carol
- Andrew Robert
- Andrews Dan
- Andrews Daniel
- Andrews Neil
- Andrews Stephanie
- Andriese Tim
- Anthouard Véronique
- Antonarakis Stylianos E.
- Anyalebechi Vivian
- Aoki Norie
- Apostolou Sinoula
- Apweiler Eva
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- Zeng Yixin
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- Zhang Guohua
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- Zhang Haiqing
- Zhang Haiqing
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- Zhang Hongbo
- Zhang Jingjing
- Zhang Jingjing
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- Zhang Jiuchun
- Zhang Jiuchun
- Zhang Lanzhi
- Zhang Li
- Zhang Li
- Zhang Meihua
- Zhang Meng
- Zhang Ming
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- Zhang Ruhua
- Zhang Shaojie
- Zhang Tiezhen
- Zhang Wei
- Zhang Wei
- Zhang Xianglin
- Zhang Xianglin
- Zhang Xiaoliang
- Zhang Xiuqing
- Zhang Yan
- Zhang Yi
- Zhang Yilin
- Zhang Yilin
- Zhang Ying
- Zhang Yuansen
- Zhang Yuzhi
- Zhang Zhengdong
- Zhao Hongmei
- Zhao Lijian
- Zhao Shenru
- Zhao Zhijing
- Zhen Zhicheng
- Zheng Haibo
- Zhong Ming
- Zhou Carol
- Zhou Haixia
- Zhou Jianling
- Zhou Nannan
- Zhou Xinfeng
- Zhou Yan
- Zhou Yang
- Zhou Yi
- Zhu Bingying
- Zhu Bofeng
- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
- Zhu Yongge
- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
Rising rural body-mass index is the main driver of the global obesity epidemic in adults
- Author
- Abarca-Gomez L
- Abdeen ZA
- Abdrakhmanova S
- Abu-Rmeileh NM
- Acosta-Cazares B
- Adams RJ
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- Yang Y
- Yardim N
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- Yiallouros PK
- Yngve A
- Yoosefi M
- Yoshihara A
- You QS
- You S-L
- Younger-Coleman NO
- Yusof SM
- Yusoff AF
- Yusoff MFM
- Zaccagni L
- Zafiropulos V
- Zainuddin AA
- Zamani F
- Zambon S
- Zampelas A
- Zamrazilova H
- Zapata ME
- Zaw KK
- Zdrojewski T
- Zeng Y
- Zhao D
- Zhao W
- Zheng W
- Zheng Y
- Zholdin B
- Zhou B
- Zhou M
- Zhu D
- Zhussupov B
- Zimmermann E
- Zuniga Cisneros J
- Publication venue
- NATURE PUBLISHING GROUP
- Publication date
- 09/05/2019
- Field of study
Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities. This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity. Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean BMI segregated by place of residence (a rural or urban area) from 1985 to 2017. We show that, contrary to the dominant paradigm, more than 55% of the global rise in mean BMI from 1985 to 2017—and more than 80% in some low- and middle-income regions—was due to increases in BMI in rural areas. This large contribution stems from the fact that, with the exception of women in sub-Saharan Africa, BMI is increasing at the same rate or faster in rural areas than in cities in low- and middle-income regions. These trends have in turn resulted in a closing—and in some countries reversal—of the gap in BMI between urban and rural areas in low- and middle-income countries, especially for women. In high-income and industrialized countries, we noted a persistently higher rural BMI, especially for women. There is an urgent need for an integrated approach to rural nutrition that enhances financial and physical access to healthy foods, to avoid replacing the rural undernutrition disadvantage in poor countries with a more general malnutrition disadvantage that entails excessive consumption of low-quality calories
Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight NCD Risk Factor Collaboration (NCD-RisC)
- Author
- Abarca-Gómez Leandra
- Abdeen Ziad A
- Abdrakhmanova Shynar
- Abu-Rmeileh Niveen M
- Acosta-Cazares Benjamin
- Adams Robert J
- Aekplakorn Wichai
- Afsana Kaosar
- Afzal Shoaib
- Agdeppa Imelda A
- Aghazadeh-Attari Javad
- Aguilar-Salinas Carlos A
- Agyemang Charles
- Ahmad Mohamad Hasnan
- Ahmad Noor Ani
- Ahmadi Ali
- Ahmadi Naser
- Ahmed Soheir H
- Ahrens Wolfgang
- Aitmurzaeva Gulmira
- Ajlouni Kamel
- Al Nsour Mohannad
- Al-Hazzaa Hazzaa M
- Al-Lahou Badreya
- Al-Raddadi Rajaa
- Alarouj Monira
- AlBuhairan Fadia
- AlDhukair Shahla
- Ali Mohamed M
- Alkandari Abdullah
- Alkerwi Ala'a
- Allin Kristine
- Alvarez-Pedrerol Mar
- Aly Eman
- Amarapurkar Deepak N
- Amiri Parisa
- Amougou Norbert
- Amouyel Philippe
- Anderssen Sigmund A
- Anjana Ranjit Mohan
- Ansari-Moghaddam Alireza
- Aounallah-Skhiri Hajer
- Araújo Joana
- Ariansen Inger
- Aris Tahir
- Arku Raphael E
- Arlappa Nimmathota
- Aryal Krishna K
- Aspelund Thor
- Assah Felix K
- Assunção Maria Cecília F
- Aung May Soe
- Auvinen Juha
- Avdicová Mária
- Avi Shina
- Azevedo Ana
- Azimi-Nezhad Mohsen
- Azizi Fereidoun
- Azmin Mehrdad
- Babu Bontha V
- Baharudin Azli
- Bahijri Suhad
- Baker Jennifer L
- Balakrishna Nagalla
- Bamoshmoosh Mohamed
- Banach Maciej
- Bandosz Piotr
- Banegas José R
- Bao Tran Quoc
- Baran Joanna
- Barbagallo Carlo M
- Barceló Alberto
- Barkat Amina
- Barros Aluisio JD
- Barros Mauro Virgílio Gomes
- Basit Abdul
- Bastos Joao Luiz D
- Bata Iqbal
- Batieha Anwar M
- Batista Rosangela L
- Battakova Zhamilya
- Batyrbek Assembekov
- Baur Louise A
- Beaglehole Robert
- Bebakar Wan Mohamad Wan
- Bel-Serrat Silvia
- Belavendra Antonisamy
- Benchekor Sounnia Mediene
- Benedics Judith
- Benet Mikhail
- Bennett James E
- Bergh Ingunn Holden
- Berkinbayev Salim
- Bernabe-Ortiz Antonio
- Bernotiene Gailute
- Bettiol Heloísa
- Bezerra Jorge
- Bhagyalaxmi Aroor
- Bharadwaj Sumit
- Bhargava Santosh K
- Bhutta Zulfiqar A
- Bi Hongsheng
- Bi Yufang
- Bia Daniel
- Bikbov Mukharram M
- Bista Bihungum
- Bixby Honor
- Bjelica Dusko J
- Bjerregaard Peter
- Bjertness Espen
- Bjertness Marius B
- Björkelund Cecilia
- Bloch Katia V
- Blokstra Anneke
- Bo Andersen Lars
- Bo Simona
- Bobak Martin
- Boddy Lynne M
- Boehm Bernhard O
- Boeing Heiner
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- Bogova Elena
- Boissonnet Carlos P
- Bojesen Stig E
- Boker Lital Keinan
- Bonaccio Marialaura
- Bongard Vanina
- Bonilla-Vargas Alice
- Bopp Matthias
- Borghs Herman
- Bovet Pascal
- Braeckevelt Lien
- Braeckman Lutgart
- Bragt Marjolijn CE
- Brajkovich Imperia
- Branca Francesco
- Braunerová Radka Taxová
- Breckenkamp Juergen
- Breda João
- Brenner Hermann
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- Brian Garry R
- Brinduse Lacramioara
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- Bugge Anna
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- Burns Con
- Cacciottolo Joseph
- Cadena Leticia Hernandez
- Cai Hui
- Cama Tilema
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- Camolas José
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- Capková Nadežda
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- Cheraghian Bahman
- Chetrit Angela
- Chikova-Iscener Ekaterina
- Chiolero Arnaud
- Chiou Shu-Ti
- Chirita-Emandi Adela
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- Cho Belong
- Christensen Kaare
- Christofaro Diego G
- Chudek Jerzy
- Cifkova Renata
- Cilia Michelle
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- Cisneros Julio Zuñiga
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- Cândido Ana Paula C
- D'Arrigo Graziella
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- Damsgaard Camilla T
- Danaei Goodarz
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- De Backer Guy
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- de León Antonio Cabrera
- de Oliveira Paula Duarte
- de Paiva Karina Mary
- De Ridder David
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- de Souza Wanderley Júnior Rildo
- de Wit Tobias F Rinke
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- Delisle Hélène
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- Demarest Stefaan
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- Dhimal Meghnath
- Di Castelnuovo Augusto F
- Di Cesare Mariachiara
- Dias-da-Costa Juvenal Soares
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- Duleva Vesselka
- Dulskiene Virginija
- Dumith Samuel C
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- Dzerve Vilnis
- Dziankowska-Zaborszczyk Elzbieta
- Díaz-Sánchez María Elena
- Döring Angela
- Eddie Ricky
- Eftekhar Ebrahim
- Egbagbe Eruke E
- Eggertsen Robert
- Eghtesad Sareh
- Ei K Nang Ei
- Eiben Gabriele
- Ekelund Ulf
- El Ati Jalila
- El-Khateeb Mohammad
- Eldemire-Shearer Denise
- Eliasen Marie
- Elliott Paul
- Engle-Stone Reina
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- Erasmus Rajiv T
- Erbel Raimund
- Erem Cihangir
- Eriksen Louise
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- Eslami Saeid
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- Fernandes Romulo A
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- Ferrario Marco M
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- Ferrer Eldridge
- Ferrieres Jean
- Figueiró Thamara Hubler
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- Filippi Sarah
- Fink Günther
- Fischer Krista
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- Fuchs Flavio D
- Fuchs Sandra C
- Fujiati Isti I
- Fujita Yuki
- Fumihiko Matsuda
- Furusawa Takuro
- Gaciong Zbigniew
- Gafencu Mihai
- Galbarczyk Andrzej
- Galenkamp Henrike
- Galeone Daniela
- Galfo Myriam
- Galvano Fabio
- Gao Jingli
- Garba Jamila Abubakar
- Garcia-de-la-Hera Manoli
- García-Solano Marta
- Gareta Dickman
- Garnett Sarah P
- Gaspoz Jean-Michel
- Gasull Magda
- Gaya Adroaldo Cesar Araujo
- Gaya Anelise Reis
- Gazzinelli Andrea
- Gehring Ulrike
- Geiger Harald
- Geleijnse Johanna M
- Ghaffar Suhaila Abdul
- Ghanbari Ali
- Ghasemi Erfan
- Gheorghe-Fronea Oana-Florentina
- Giampaoli Simona
- Gianfagna Francesco
- Gill Tiffany K
- Giovannelli Jonathan
- Gironella Glen
- Giwercman Aleksander
- Gkiouras Konstantinos
- Godos Justyna
- Gogen Sibel
- Goldberg Marcel
- Goldsmith Rebecca A
- Goltzman David
- Gomula Aleksandra
- Gonzalez Angel R
- Gonzalez-Chica David A
- Gonzalez-Gross Marcela
- González-Leon Margot
- González-Rivas Juan P
- González-Villalpando Clicerio
- González-Villalpando María-Elena
- Gonçalves Helen
- Gottrand Frederic
- Graff-Iversen Sidsel
- Grafnetter Dušan
- Grajda Aneta
- Grammatikopoulou Maria G
- Graça Antonio Pedro
- Gregg Edward W
- Gregor Ronald D
- Grodzicki Tomasz
- Grosso Giuseppe
- Gruden Gabriella
- Grøholt Else Karin
- Grøntved Anders
- Gu Dongfeng
- Gualdi-Russo Emanuela
- Guallar-Castillón Pilar
- Gualtieri Andrea
- Gudmundsson Elias F
- Gudnason Vilmundur
- Guerrero Ramiro
- Guessous Idris
- Guimaraes Andre L
- Gulliford Martin C
- Gunnlaugsdottir Johanna
- Gunter Marc J
- Guo Xiu-Hua
- Guo Yin
- Gupta Prakash C
- Gupta Rajeev
- Gureje Oye
- Gurzkowska Beata
- Gutierrez Laura
- Gutiérrez-González Enrique
- Gutzwiller Felix
- Gómez Santiago F
- Ha Seongjun
- Hadaegh Farzad
- Hadjigeorgiou Charalambos A
- Haghshenas Rosa
- Hakimi Hamid
- Halkjær Jytte
- Hambleton Ian R
- Hamzeh Behrooz
- Hange Dominique
- Hanif Abu AM
- Hantunen Sari
- Hao Jie
- Hashemi-Shahri Seyed Mohammad
- Hassapidou Maria
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- He Yuan
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- Heidinger-Felso Regina
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- Hendriks Marleen Elisabeth
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- Herrala Sauli
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- Heshmat Ramin
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- Ho Suzanne C
- Hobbs Michael
- Holdsworth Michelle
- Homayounfar Reza
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- Hopman Wilma M
- Horimoto Andrea RVR
- Hormiga Claudia M
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- Houti Leila
- Howitt Christina
- Htay Thein Thein
- Htet Aung Soe
- Htike Maung Maung Than
- Hu Yonghua
- Huerta José María
- Huhtaniemi Ilpo Tapani
- Huiart Laetitia
- Huisman Martijn
- Husseini Abdullatif
- Huu Chinh Nguyen
- Huybrechts Inge
- Hwalla Nahla
- Hyska Jolanda
- Iacoviello Licia
- Ibarluzea Jesús M
- Ibrahim Mohsen M
- Ikeda Nayu
- Ikram M Arfan
- Ioannidou Eliza Markidou
- Iotova Violeta
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- Ishida Takafumi
- Islam Muhammad
- Islam Sheikh Mohammed Shariful
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- Jamrozik Konrad
- Janszky Imre
- Janus Edward
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- Jasienska Grazyna
- Jelakovic Ana
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- Kersting Mathilde
- Key Timothy
- Khader Yousef Saleh
- Khalili Davood
- Khang Young-Ho
- Khaw Kay-Tee
- Kheiri Bahareh
- Kheradmand Motahareh
- Khosravi Alireza
- Khouw Ilse MSL
- Kiechl Stefan
- Kiechl-Kohlendorfer Ursula
- Killewo Japhet
- Kim Dong Wook
- Kim Hyeon Chang
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- Kindblom Jenny M
- Klakk Heidi
- Klimek Magdalena
- Klimont Jeannette
- Klumbiene Jurate
- Knoflach Michael
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- Kolsteren Patrick
- Korpelainen Raija
- Korrovits Paul
- Korzycka Magdalena
- Kos Jelena
- Koskinen Seppo
- Kouda Katsuyasu
- Kovacs Viktoria A
- Kowlessur Sudhir
- Koziel Slawomir
- Kratenova Jana
- Kratzer Wolfgang
- Kriemler Susi
- Kristensen Peter Lund
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- Kromhout Daan
- Kruger Herculina S
- Kubinova Ruzena
- Kuciene Renata
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- Kumar R Krishna
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- Kurjata Pawel
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- Kuulasmaa Kari
- Kyobutungi Catherine
- Kårhus Line L
- König Jürgen
- la Peña Jorge Escobedo-de
- La Quang Ngoc
- Laamiri Fatima Zahra
- Laatikainen Tiina
- Lachat Carl
- Laid Youcef
- Lam Tai Hing
- Lambrinou Christina-Paulina
- Landais Edwige
- Lanska Vera
- Lappas Georg
- Larijani Bagher
- Latt Tint Swe
- Lauria Laura
- Laxmaiah Avula
- Lazo-Porras Maria
- Le Coroller Gwenaëlle
- Le Nguyen Bao Khanh
- Le Port Agnès
- Le Tuyen D
- Lee Jeannette
- Lee Jeonghee
- Lee Paul H
- Lehmann Nils
- Lehtimäki Terho
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- Levitt Naomi S
- Li Chee Miao
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- Liivak Merike
- Lilly Christa L
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- Lima-Costa M Fernanda
- Lin Hsien-Ho
- Lin Xu
- Lin Yi-Ting
- Lind Lars
- Linneberg Allan
- Lissner Lauren
- Litwin Mieczyslaw
- Liu Jing
- Liu Lijuan
- Lo Wei-Cheng
- Loit Helle-Mai
- Long Khuong Quynh
- Lopes Luis
- Lopes Oscar
- Lopez Tania
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- Rahimikazerooni Salar
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- Rahman Mahmudur
- Raitakari Olli
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- Rakhmatulloev Sherali
- Rakovac Ivo
- Ramachandran Ambady
- Ramke Jacqueline
- Ramos Elisabete
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- Regecová Valéria
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- Salanave Benoit
- Salmerón Diego
- Salomaa Veikko
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- Salvetti Massimo
- Samoutian Margarita
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- Sans Susana
- Sant'Angelo Victoria Farrugia
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- Schargrodsky Herman
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- Wagner Aline
- Waldhör Thomas
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- Wang Ming-Dong
- Wang Ningli
- Wang Qian
- Wang Xiangjun
- Wang Ya Xing
- Wang Ying-Wei
- Wannamethee S Goya
- Wareham Nicholas
- Weber Adelheid
- Wedderkopp Niels
- Weerasekera Deepa
- Weghuber Daniel
- Wei Wenbin
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- Whincup Peter H
- Widhalm Kurt
- Widyahening Indah S
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- Wilks Rainford J
- Willeit Johann
- Willeit Peter
- Williams Julianne
- Wilsgaard Tom
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- Wong Andrew
- Wong Jyh Eiin
- Wong Norazizah Ibrahim
- Wong Tien Yin
- Wong-McClure Roy A
- Woo Jean
- Woodward Mark
- Wu Frederick C
- Wu Jianfeng
- Wu Li Juan
- Wu Shouling
- Xu Haiquan
- Xu Liang
- Yaacob Nor Azwany
- Yamborisut Uruwan
- Yan Weili
- Yang Ling
- Yang Xiaoguang
- Yang Yang
- Yardim Nazan
- Yaseri Mehdi
- Yasuharu Tabara
- Ye Xingwang
- Yiallouros Panayiotis K
- Yoosefi Moein
- Yoshihara Akihiro
- You Qi Sheng
- You San-Lin
- Younger-Coleman Novie O
- Yusoff Ahmad Faudzi
- Yusoff Muhammad Fadhli Mohd
- Zaccagni Luciana
- Zafiropulos Vassilis
- Zainuddin Ahmad A
- Zakavi Seyed Rasoul
- Zamani Farhad
- Zambon Sabina
- Zampelas Antonis
- Zamrazilová Hana
- Zapata Maria Elisa
- Zargar Abdul Hamid
- Zdrojewski Tomasz
- Zejglicova Kristyna
- Zeng Yi
- Zhang Luxia
- Zhang Zhen-Yu
- Zhao Dong
- Zhao Ming-Hui
- Zhao Wenhua
- Zhen Shiqi
- Zheng Wei
- Zheng Yingfeng
- Zholdin Bekbolat
- Zhou Bin
- Zhou Maigeng
- Zhu Dan
- Zins Marie
- Zitt Emanuel
- Zocalo Yanina
- Zuziak Monika
- Ängquist Lars
- Łuszczki Edyta
- Ševcíková Ludmila
- Publication venue
- eLife Sciences Publications
- Publication date
- 01/01/2021
- Field of study
From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of underweight, obesity, and severe obesity in different regions using data from 2896 population-based studies with 187 million participants. Changes in the prevalence of underweight and total obesity, and to a lesser extent severe obesity, are largely driven by shifts in the distribution of BMI, with smaller contributions from changes in the shape of the distribution. In East and Southeast Asia and sub-Saharan Africa, the underweight tail of the BMI distribution was left behind as the distribution shifted. There is a need for policies that address all forms of malnutrition by making healthy foods accessible and affordable, while restricting unhealthy foods through fiscal and regulatory restrictions