19 research outputs found
Random Matrix Theories in Quantum Physics: Common Concepts
We review the development of random-matrix theory (RMT) during the last
decade. We emphasize both the theoretical aspects, and the application of the
theory to a number of fields. These comprise chaotic and disordered systems,
the localization problem, many-body quantum systems, the Calogero-Sutherland
model, chiral symmetry breaking in QCD, and quantum gravity in two dimensions.
The review is preceded by a brief historical survey of the developments of RMT
and of localization theory since their inception. We emphasize the concepts
common to the above-mentioned fields as well as the great diversity of RMT. In
view of the universality of RMT, we suggest that the current development
signals the emergence of a new "statistical mechanics": Stochasticity and
general symmetry requirements lead to universal laws not based on dynamical
principles.Comment: 178 pages, Revtex, 45 figures, submitted to Physics Report
Transcriptome Analysis of the Desert Locust Central Nervous System: Production and Annotation of a Schistocerca gregaria EST Database
) displays a fascinating type of phenotypic plasticity, designated as ‘phase polyphenism’. Depending on environmental conditions, one genome can be translated into two highly divergent phenotypes, termed the solitarious and gregarious (swarming) phase. Although many of the underlying molecular events remain elusive, the central nervous system (CNS) is expected to play a crucial role in the phase transition process. Locusts have also proven to be interesting model organisms in a physiological and neurobiological research context. However, molecular studies in locusts are hampered by the fact that genome/transcriptome sequence information available for this branch of insects is still limited. EST information is highly complementary to the existing orthopteran transcriptomic data. Since many novel transcripts encode neuronal signaling and signal transduction components, this paper includes an overview of these sequences. Furthermore, several transcripts being differentially represented in solitarious and gregarious locusts were retrieved from this EST database. The findings highlight the involvement of the CNS in the phase transition process and indicate that this novel annotated database may also add to the emerging knowledge of concomitant neuronal signaling and neuroplasticity events. EST data constitute an important new source of information that will be instrumental in further unraveling the molecular principles of phase polyphenism, in further establishing locusts as valuable research model organisms and in molecular evolutionary and comparative entomology
Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes
publisher: Elsevier articletitle: Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes journaltitle: Cell articlelink: https://doi.org/10.1016/j.cell.2018.05.046 content_type: article copyright: © 2018 Elsevier Inc