Die Philosophie des auslandes vom beginn Des 19. Jahrhunderts...

Baselxi, 431 p.; 23 cm

B cell signatures and tertiary lymphoid structures contribute to outcome in head and neck squamous cell carcinoma

Recent studies have highlighted the importance of B cells and tertiary lymphoid structures (TLS) in the modulation of anti-tumor immune responses. Here, the authors characterize how HPV status influences the phenotype of tumor infiltrating B cells in patients with head and neck squamous cell carcinoma and demonstrate that TLS with germinal centres are associated with better survival