Mental Health in Eastern Europe during the COVID-19 Pandemic: A Systematic Review and Meta-Analysis of Depression and Anxiety

Objective: To perform a systematic review and meta-analysis on the prevalence rate of mental health disorders including anxiety, depression, and insomnia during the COVID-19 pandemic in Eastern Europe in the general population, as well as within select sub-populations (i.e., students, general healthcare workers, and frontline workers). Data sources: Articles in PubMed, Embase, Web of Science, Psycinfo, and medRxiv up to February 20th, 2021. Eligibility criteria and data analysis: Prevalence rate of mental disorders in the general population and select sub-populations during the COVID-19 pandemic in Eastern Europe. Data was pooled using a random-effects meta-analysis in order to estimate the prevalence rates of clinically significant symptoms of depression and anxiety. Results: The meta-analysis identifies and includes 21 studies and 26 independent samples in Eastern Europe. Poland (n=4), Serbia (n=4), Russia (n=3), and Croatia (n=3) represented the greatest number of studies. To our knowledge, no studies were conducted in 11 Eastern European countries such as Armenia, Azerbaijan, and Belarus. The pooled prevalence of anxiety in 18 studies with a pooled sample of 22 was 30% (95% CI: 24% - 37%, I²: 99.6%) and that of depression in 18 studies with a pooled sample of 23 was 27% (95% CI: 21% - 34%, I²: 99.6%). The analysis indicated high heterogeneity and varying prevalence rates. Discussion: The cumulative evidence from the meta-analysis reveals that there are high prevalence rates of clinically significant symptoms in Eastern Europe during the COVID-19 crisis. The findings suggest a significant public health burden in Eastern Europe attributable to COVID-19 during pandemic. Our synthesis also reveals high heterogeneity and a relative lack of studies in certain Eastern European countries, calling future research and interventions to pay more attention to those gaps to help inform evidence-based mental health policymaking and practice in Eastern Europe.Key Words: Meta-Analysis; COVID-19; Mental Health; Epidemic; General Population; Healthcare Workers; Frontline Healthcare Workers; Anxiety; Depression; Psychiatry; Central Europe; Eastern Europ

RELATIONSHIP BETWEEN KINEMATIC CHARACTERISTICS AND FREE-THROW SHOOTING PRECISION: MARKERLESS MOTION CAPTURE ANALYSIS

The search for aspects of basketball shooting that characterize successful performance is an area of focus for sports biomechanists. However, the systematic evaluation of these key elements during shooting practice is limited due to the time it takes to collect and/or process the data. Thus, the purpose of the present study was to evaluate the relationship between some of the key kinematic variables extracted from a markerless motion capture system on free-throw shot performance. Multivariable linear regression analysis indicated that shot plane alignment, trunk rotation, entry angle, and timing of elbow extension were some of the key contributors to free-throw shot precision. Overall, these kinematic variables serve as a preliminary set of outcomes that can be reported to coaches and players that decide to use markerless motion capture technology for free-throw shooting biomechanical analysis

Ethics of controlled human infection to study COVID-19

Development of an effective vaccine is the clearest path to controlling the coronavirus disease 2019 (COVID-19) pandemic. To accelerate vaccine development, some researchers are pursuing, and thousands of people have expressed interest in participating in, controlled human infection studies (CHIs) with severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2) (1, 2). In CHIs, a small number of participants are deliberately exposed to a pathogen to study infection and gather preliminary efficacy data on experimental vaccines or treatments. We have been developing a comprehensive, state-of-the-art ethical framework for CHIs that emphasizes their social value as fundamental to justifying these studies. The ethics of CHIs in general are underexplored (3, 4), and ethical examinations of SARS-CoV-2 CHIs have largely focused on whether the risks are acceptable and participants could give valid informed consent (1). The high social value of such CHIs has generally been assumed. Based on our framework, we agree on the ethical conditions for conducting SARS-CoV-2 CHIs (see the table). We differ on whether the social value of such CHIs is sufficient to justify the risks at present, given uncertainty about both in a rapidly evolving situation; yet we see none of our disagreements as insurmountable. We provide ethical guidance for research sponsors, communities, participants, and the essential independent reviewers considering SARS-CoV-2 CHIs

Mental Disorder Symptoms during the COVID-19 Pandemic in Latin America – A Systematic Review and Meta-analysis

Aims There is a lack of evidence related to the prevalence of mental health symptoms as well as their heterogeneities during the coronavirus disease 2019 (COVID-19) pandemic in Latin America, a large area spanning the equator. The current study aims to provide meta-analytical evidence on mental health symptoms during COVID-19 among frontline healthcare workers, general healthcare workers, the general population and university students in Latin America. Methods Bibliographical databases, such as PubMed, Embase, Web of Science, PsycINFO and medRxiv, were systematically searched to identify pertinent studies up to August 13, 2021. Two coders performed the screening using predefined eligibility criteria. Studies were assigned quality scores using the Mixed Methods Appraisal Tool. The double data extraction method was used to minimise data entry errors. Results A total of 62 studies with 196 950 participants in Latin America were identified. The pooled prevalence of anxiety, depression, distress and insomnia was 35%, 35%, 32% and 35%, respectively. There was a higher prevalence of mental health symptoms in South America compared to Central America (36% v. 28%, p \u3c 0.001), in countries speaking Portuguese (40%) v. Spanish (30%). The pooled prevalence of mental health symptoms in the general population, general healthcare workers, frontline healthcare workers and students in Latin America was 37%, 34%, 33% and 45%, respectively. Conclusions The high yet heterogenous level of prevalence of mental health symptoms emphasises the need for appropriate identification of psychological interventions in Latin America

Tephra without borders: Far-reaching clues into past explosive eruptions

This review is intended to highlight recent exciting advances in the study of distal (>100 km from the source) tephra and cryptotephra deposits and their potential application for volcanology. Geochemical correlations of tephra between proximal and distal locations have extended the geographical distribution of tephra over tens of millions square kilometers. Such correlations embark on the potential to reappraise volume and magnitude estimates of known eruptions. Cryptotephra investigations in marine, lake and ice-core records also give rise to continuous chronicles of large explosive eruptions many of which were hitherto unknown. Tephra preservation within distal ice sheets and varved lake sediments permit precise dating of parent eruptions and provide new insight into the frequency of eruptions. Recent advances in analytical methods permit an examination of magmatic processes and the evolution of the whole volcanic belts at distances of hundreds and thousands of kilometers from source. Distal tephrochronology has much to offer volcanology and has the potential to significantly contribute to our understanding of sizes, recurrence intervals and geochemical make-up of the large explosive eruptions