214 research outputs found
Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis
- Author
- Aahlin Eirik Kjus
- Aamer Ahmed
- Aaniana Kenneth
- Ababneh Ali
- Abaliksta Tomas
- Abantanga Francis
- Abbas Athar
- Abbasy Jibran
- Abbo Olivier
- Abbott Tom
- Abbouch Meryem
- Abd El-Latif Nadia Khalid
- Abd Elkhalek Esraa
- Abd-Elmawla Manar
- Abdallah Emad
- Abdel-Aty Abdulrahman
- Abdel-Hameed Noran
- Abdel-Kader Sara Mahmoud
- Abdelaal Abdelaziz
- Abdelaty Mohamed
- Abdelazeam Anan Rady
- Abdelazim Galaleldin
- Abdelaziz Mohamed A.
- Abdelbadeai Kholoud
- Abdelfatah Afnan
- Abdelhady Samar
- Abdelhamed Rasha
- Abdelhamid Amina
- Abdelhaq Aram
- Abdelkader Mostafa
- Abdelkader Omar
- Abdelkhalek Mohamed
- Abdelmageed Eman
- Abdelmotaleb Ibrahem
- Abdelraouf Ahmed Mahmoud
- Abdelrouf Doaa Maher
- Abdelshakour Mahmoud
- Abdrabou Abdulshafi Khaled
- Abdul-Latif Saiba
- Abdulaziz Hager
- Abdulaziz Mustafa
- Abdulbagi Omar
- Abdulhakeem Eman Mahmoud
- Abdullah Mohamed Abozed
- Abdullah Nik Azim Nik
- Abdullah Noha
- Abdullahi Lawal
- Abdurrazzaaq Abdussemiu
- Abem Owusu Emmanuel
- Abiola Olajide
- Aboelella Majed
- Aboelmagd Omnia
- Aboelsoud Moustafa R.
- Aboul-Naga Mariam Saad
- Abouzaid Arwa
- Abu Qumbos Amjad
- Abu-toyour Maram
- Abubakr Marwan
- Abuowda Yousef
- Abuqwaider Eman
- Abusalem Lana
- Abushamleh Soha
- Ackom Eric
- Acquah Emmanuel
- Adam Ali
- Adam Nourhan
- Adamu Ahmed
- Adawi Ihdaa
- Adawi Mohammad
- Adebanjo Ademola
- Adebola Oluwaseyi
- Adedeji Adesina
- Adel Badr Eldin
- Adel Israa
- Adella Fidelis Jacklyn
- Adelshone Abdelrahman
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji O.
- Ademuyiwa Adesoji O.
- Adenekan Babajide
- Adeniran James
- Adeniyi Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adeyeye Ademola
- Adeyeye Ademola
- Adhitama Novia
- Adil Muhammad
- Adisa Adewale O.
- Adiyaman Can
- Adu-Aryee Niiarmah
- Afana Samah
- Agalianos Christos
- Agarwal Arnav
- Agarwal Arnav
- Agbedinu Kwabena
- Aglan Amro
- Aguado Suarez Nuria
- Aguilera Maria Lorena
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlonsou Germain
- Ahlqvist Sandra
- Ahlqvist Sandra
- Ahmed Asdaq
- Ahmed Ataa
- Ahmed Hayam
- Ahmed Hussien
- Ahmed Lopna Ahmed Mohamed
- Ahmed Sara
- Ahmed Saraibrahim
- Ahounou Ernest Yemalin Stephane
- Ajah Jonathan
- Ajai Olalekan
- Ajao Akinlabi
- Ajiboye Anthony
- Akoto Elliot
- Akpenyi Onyinye
- Al Amin Shadid
- Al Attar Samaa Mahmoud
- Al Barraw Fayez Elian
- Al Bastawis Fatema
- Al Meligy Amgad
- Al Rafati Ahmad Abdel Razaq
- Al Raouf Eman Abd
- Al Saied Ghiath
- Al Subaie Norah
- Al-Bahrani Ahmed
- Al-Buhaisi Alaa
- Al-Dakka Emad
- Al-faqawi Maha
- Al-farram Hadeel
- Al-khatib Ahmed
- Al-Marakby Dina
- Al-saqqa Sara
- Al-Saqqa Sara W.
- Al-Slaibi Ibrahim
- Al-taher Taher
- AlaaelDein Shahinaz
- Alada Muslimat
- Alakaloko Felix
- Alaloul Enas
- Alamin Shadid
- Alamoudi Mohammed
- Albiety Adel
- Alcca Ticona Willy
- Alejos Bermudez Ysabel Esthefany
- Alexander Philip
- Alexander Philip
- Alexandre Challine
- Alghamdi Ahmed
- Alghamdi Mohammed Saleh A.
- Alhady Khaled
- Alhammali Tariq
- Alhassan Basmah
- Alhazmi Wedyan
- Alherz Mohammad
- Ali Ahmed
- Ali Citra Dewi Mohd
- Ali Elsayed
- Ali Safia
- Ali Syed Abdul Wahhab Eusoffee Wan
- Ali Tebian Hassanein Ahmed
- Ali Wadah
- Alihonou Thierry
- Alis Halil
- Aliyu Halima
- Aliyu Mohammad
- Aliyu Shamsudeen
- Aljboor Khaled
- Aljiffry Murad
- Alkaaki Aroub
- Alkelani Muhammad
- Allam Meran
- Allam Yomna
- Alnaby Mohamed Hassab
- Alnusairat Aseel
- Alqahtani Saleh
- Alsaggaf Mohammed Ubaid
- Alser Osaid H.
- Alshareef Reham
- Altaf Abdulmalik
- Altamimi Abdullah
- Altamimi Afnan
- Altamini Afnan
- Altarayra Marwa
- Altibi Ahmed
- Altinel Yuksel
- Altinel Yuksel
- Altwijri Abdulaziz
- Alvi Abdul Rehman
- Aly Mohammed Yahia Mohamed
- Alyacoubi Said
- Alyahya Reem
- Alzahrani Ahmed
- Aman Nowrin F.
- Amandito Radhian
- Amandito Radhian
- Ambrona-Zafra David
- Amin Hager Abdul Aziz
- Amjad Mohammadasim
- Amoah Michael
- Amoako Joachim
- Amoako Philip Taah
- Amoako-Boateng Mabel
- Amole Isaac
- Amreia Mahmoud
- Anderson Frank
- Andika Ferry Fitriya Ayu
- Andreotti Dario
- Andress Cedar
- Andriola Valeria
- Ang Yun Lin
- Angelieri Daniele
- Anis Echaieb
- Ansaloni Luca
- Ansaloni Luca
- Ansaloni Luca
- Antezana Diego
- Anthoulakis Christos
- Antoniozzi Angelo
- Anwar Nourhan
- Anyanwu Lofty-John
- Aonzo Paolo
- Appeadu-Mensah William
- Appiah Eric Kofi
- Aquilino Fabrizio
- Arafa Omar
- Arafa Sara
- Arango Maria Clara Mendoza
- Arcudi Claudio
- Armellini Andrea
- Arnaud Alexis
- Arnaud Alexis Pierre
- Arshad Mohammad Mohsin
- Arslan Ekin
- Arsyad Hasbi Maulana
- Arthur Tom
- Aruldas Neerav
- Asar Yomna Hosny
- Asare-Bediako Kwasi
- Ashour Ahmad
- Ashour Ahmad
- Ashour Khlood
- Ashtari Morvarid
- Asi Fatema
- Asilah Siti Mohd Desa
- Assal Abdelrahman
- Asturias Sabrina
- Asumah Hamza
- Ata Ahmed
- Ata Aya Yehia
- Atiyeh Anwar
- Atkins Ebenezer Takyi
- Attia Attia
- Augestad Knut Magne
- Aviles Susan
- Avoka Anthony
- Awad Israa
- Awad Sawsan Adel
- Awadallah Salwa
- Ayandipo Omobolaji
- Aydin Mehmet Can
- Aziz Dayang Nita Abdul
- Aziz Mohamed Rezal Abdul
- Aziz Nora Abdul
- Azizeldine Mohammed G.
- Azzie Georges
- Azzis Olivier
- Baba Suleiman
- Bachri Houda
- Badawy Mahmoud
- Badenjki Mohamed Adel
- Badicel Maria
- Badr Mohamed Fawzy Mahrous
- Badwi Nermin Mohamed
- Bahar Suraya
- Baillie Katie
- Baki Bahadir Emre
- Bakr Ahmad
- Bakry Hesham Mohammed
- Bala Miklosh
- Balalis Dimitrios
- Balducci Genoveffa
- Ballouhey Quentin
- Balmaceda Ruben
- Balmaceda Ruben
- Balogun Fatai
- Baltrunas Robertas
- Baluch Fatima
- Bamford Rebecca
- Bamicha Athanasia
- Banaitis Vincas Jonas
- Bandi Ashwath
- Bandoh Dickson
- Bani-Sadar Ahmad
- Banipal Gurpreet Singh
- Baquero Suarez Alibeth Andres
- Baraka Heba
- Barendegere Venerand
- Barkolias Christos
- Barmayehvar Behrad
- Barnabas Gandau Naa
- Barrios Emmanuel
- Basilico Silvia
- Basir Elissa Rifhan Mohd
- Bassem Monica
- Bassit Khalil Abdul
- Basso Stefano M. M.
- Bayram Sefa
- Beamon Mieshia
- Bedada Alemayehu Ginbo
- BediakoBowan Antoinette
- Bekhet Amira Hassan
- Bekhet Nada Mohamed
- Beleno Alvaro Enrique Mendoza
- Belkouchi Abdelkader
- Belli Andrea
- Bello Bashir
- Benammi Sarah
- Benevento Angelo
- Bennai Redouane Mammar
- Bentounsi Zineb
- Benyaiche Chaymae
- Berti Stefano
- Bertuello Isaac
- Beuran Mircea
- Bhangu Aneel
- Bhangu Aneel
- Bhangu Anna
- Bhatnagar Ankur
- Bhopal Kamran Faisal
- Bianco Federica
- Bigaran Annamaria
- Billy Matthew
- Bin Adnan Ahmad
- Bin Hasnan Muhammad
- Bin Ismail Mohamad Jeffrey
- Birindelli Arianna
- Bisset Carly
- Bjorklund Ida
- Blacker Sarah
- Blackwell James
- Blanco Ruth
- Blanco-Colino Ruth
- Blencowe Natalie
- Bliksoen Marte
- Bluelle Rafael
- Bocchetti Tommaso
- Bode Chris
- Bodur Selim
- Boggon Adam
- Bonavia Karl
- Bonavina Luigi
- Bond-Smith Giles
- Bondin John
- Bondurri Andrea
- Boni Silvia
- Bonney William
- Borda-Luque Giuliano
- Borg Elaine
- Borg Elaine
- Bortolasi Luca
- Bottini Corrado
- Bougard Heather
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- Bowling Kirk
- Bradulskis Saulius
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- Breaud Jean
- Breistrand Michaela
- Breslin Ryan
- Brincat Svetlana Doris
- Broch Aline
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- Bsisu Isam
- Bucci Luigi
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- Bunting David
- Burger Sule
- Burmistrovas Andrius
- Bustangi Nasir
- Bustangi Nasir
- Butt Muhammad Talha
- Cakaloglu Haluk Cem
- Caliman Celeste
- Callan Rory
- Camilleri Georgette Marie
- Camilleri-Brennan Julian
- Campagnaro Tommaso
- Canta Calua Alexander
- Capito Carmen
- Carabott Kurt
- Carmela Lapitan Marie
- Carmona Juan Manuel
- Carpio Juan
- Carrasco Nahilia
- Cassar Kristina
- Catani Marco
- Cautiero Roberto
- Caydiid Hanaan
- Cecilia Tolg
- Celik Saban
- Cengiz Turgut Bora
- Cengiz Yucel
- Cengiz Yucel
- Cevik Muazzez
- Chabok Abbas
- Chai Chu-Ann
- Chai Feng Yih
- Chan Luke
- Chan Tsz-Yan Katie
- Chan Xue Wei
- Charles Angeline
- Cheah Alvin Ee Zhiun
- Chen Kar Yan
- Chen Tzu-Ling
- Cheong Yih Jeng
- Chetta Nicola
- Cheung Yuk Hong Eric
- Chibuye Chali
- Chiesa Deborah
- Chilton Gareth
- Chin Pui Xin
- Chin Ye Ru
- Chiu Seehui
- Choi Philip
- Chong Choon Seng
- Chong Hoong-Yin
- Choudhry Asad
- Chow Crystal Yern Nee
- Chowdhury Debkumar
- Chu Kathryn
- Chung Kuet Jun
- Chungui Bravo Jorge Armando
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- Clarissa Audrey
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- Coccolini Federico
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- Cole Simon
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- Conci Simone
- Confalonieri Gianmaria
- Conlon Kevin C.
- Connor Katie
- Contreras Elisa
- Coompson Christian Lari
- Corbellini Carlo
- Corbellino Mario
- Cornick Jen
- Coronel Jazmin
- Corral Moreno Sara
- Correa Juan Camilo
- Corro-Diaz Samantha
- Costa Cecilia
- Costa-Maia Jose
- Costas-Chavarri Ainhoa
- Courboin Etienne
- Cox Daniel
- Cox Michael
- Coyoy-Gaitan Otto
- Craus-Miguel Andrea
- Cullen Fraser
- Curletti Gianluca
- Currow Chelise
- D'Amours Scott
- D'Souza Michelle S.
- Dabboor Majd
- Dabbour Kareem
- Dagoe Enoch
- Dahy Ahmed
- Dainius Edvinas
- Dakubo Jonathan
- Dalli Jeffrey
- Dally Charles
- Dambrauskas Zilvinas
- Daniyan Muhammad
- Danys Donatas
- Dao Weihei
- Dar Wasim
- Dardenne Sabrina
- Darwish Abdelrhman K. Z.
- Dasari Mohini
- Dashnyam Enkhbat
- Dassah Victor
- Datta Uttaran
- Davies Rachel
- Davor Anthony
- Dawood Khaled
- Dayie Makafui
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- Drake Thomas M.
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- Elnajjar Mahmoud A.
- Elrazek Aly Abd
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- Elsameea Ahmed Abd
- Elsawy Amira
- Elsayed Nada Ahmed Reda
- Elsemelawy Rofida
- Elshaar Mohammed
- Elshaer Mohamed
- Elshami Mohamedraed
- Elsharkawy Aya Adel
- Elsherbiney Saged
- Elsherif Fawzia Abdellatif
- Elwy Eman
- Elzahed Nada
- Emadeldin Hossam
- Emara Eman
- Emile Sameh
- Eng Calvin
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- Esam Abeer
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- Espinoza Fernando
- Essam A. A.
- Essam Ahmed
- Essam Mahitab
- Essoun Samuel
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- Etienne Sara
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- Evajelista Cicilia Viany
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- Evans Elizabeth
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- Farag Sameh
- Farahat Mahitab Morsy
- Fares Mohamed
- Farhan-Alanie Muhamed M. H.
- Farhangmehr Neda
- Farouk Sara Amr Mohamed
- Farrugia Alexia
- Farrugia Alexia
- Faruq Amreen
- Fathy Aya Mohamed
- Fatuga Adedeji
- Faturoti Olubukola
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- Feidantsis Thomas
- Fergany Alaa
- Fergusson Stuart J.
- Fergusson Stuart J.
- Fermani Claudio Gabriel
- Fernandes Cristina
- Fernandez Carmen
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- Ferousis Christoforos
- Ferrero Esther
- Filatau Aliaksandr
- Firdouse Mohammed
- Firdouse Mohammed
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- Fitsum Agazi
- Fitzgerald J. Edward
- Fitzgerald J. Edward
- Florez Farfan Erick Samuel
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- Gaafar Shireen
- Gaarder Tina
- Gad Ahmed
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- Gadelkarim Mohamed
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- Har Prisca A. L.
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- Harrison Ewen M.
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- Helguero-Santin Luis M.
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- Ibraheem Aya AbdelFatah
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- Ingabire J. C. Allen
- Ingabire J. C. Allen
- Ioannidis Orestis
- Iqbal Muhammad Rafaih
- Ireland Philip
- Irtan Sabine
- Irwin Gareth
- Irwin Gareth
- Ishak Norzawani
- Iskandar Ferdy
- Isler Vedatcan
- Ismail Ahmed
- Ismail Lawani
- Ismail Lawani
- Ismail Lawani
- Ismail Lawani
- Ismail Mohamed
- Ismail Mohammed Kamal
- Ismail Samar Adel
- Israelsson Leif
- Ivros Nikolaos
- Iyer Dush
- Iyer Dushyant
- Jabal Mohamed Sobhi
- Jaber Sahar
- Jaffry Zahra
- Jaich Robert
- Jama Guled M.
- Jamal Luai
- Janardha K. C.
- Janik Michal
- Jankus Tomas
- Jaradat Dana
- Jasaitis Kristijonas
- Javaid Mahnoor
- Jayathilake A. B.
- Jean-Francois Colombani
- Jeffery Anna
- Jeffery Anna
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- Jensen Elisabeth
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- Jeon Hyunjin
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- Jethwani Durvesh Lacthman
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- Jimenez-Morillas Patricia
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- Kamarajah Sivesh K.
- Kamarulzamil Siti Nur Alia
- Kamya Sylvia
- Kanani Arezo
- Kandil Ahmedali M.
- Kandil Hend
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- Keogh Kenneth
- Kershaw Suzanne
- Khafagy Toqa
- Khalifah Eyad
- Khallaf Salwa
- Khamajeet Arvin
- Khan Maryam Ali
- Khan Roaa
- Khan Zain Ali
- Khatri Chetan
- Khoja Ahmad
- Khokha Dzianis
- Khokha Vladimir
- Khosla Shivun
- Khreishi Reem
- Khreishi Rose
- Khulu Lawrence Bongani
- Kidd Thomas
- Kinandu Kamau
- King Sebastian
- Kiran Ravi P.
- Kirby Andrew
- Kiudelis Mindaugas
- Klappenbach Roberto
- Knight Stephen
- Koay Kean Leong
- Kobal Berna Buse
- Koh Pei Ying
- Koh Sharon
- Kojo Anyomih Theophilus Teddy
- Kojo Anyomih Theophilus Teddy
- Kondrotas Paulius
- Kong Chia
- Kong Shu Ning
- Kong Victor
- Konstantina Kolonia
- Kordorwu Hope Edem Kofi
- Korkolis Dimitrios
- Kosai Nik Ritza
- Kose Emin
- Koskenvuo Laura
- Koto Modise Zacharia
- Kotobi Henri
- Kourdouli Amar
- Kourdouli Amar
- Kufeji Dorothy
- Kuliavas Justas
- Kumar Basant
- Kumar Basant
- Kumar Basant
- Kumar Sandip
- Kumar Sunil
- Kumar Sunil
- Kumwenda Dayson
- Kushwaha Sameer
- Kusi Kwasi
- Kutkevicius Juozas
- Kwakyeafriyie Prince
- Kwatiwani Chimwemwe
- Kwizera Sandrine
- Kwok Stephanie Hiu-wai
- Kyereh Martin
- Kyriazanos Ioannis
- Kyrou Georgios
- Kyziridis Dimitrios
- L'Heveder Ariadne
- La Brocca Antonella
- Ladukas Adomas
- Lagunavicius Karolis
- Lai Anthony Chuk-Him
- Lam Justin Chak Yiu
- Lam Wai Him
- Lanau Maria Isabel Villegas
- Lando Justus
- Landolfo Giovanni
- Lapitan Marie Carmela
- Larsen Johannes Wiik
- Lasek Anna
- Latif Aliang
- Laugzemys Erikas
- Laurie Kirsten
- Lauzikas Giedrius
- Law Jia Hao
- Lawal Abdulrazzaq
- Lawal Taiwo
- Lazzari Giovanni
- Lazzari Veronica
- Le Vu Thanh Hien
- Leanne Almanon Christel
- Lecompte Jean-Francois
- Lee Eu Xian
- Lee Felix
- Lee Kai Yin
- Lee Kathryn
- Lee Kuok Chung
- Lee Tien Seng Bryan
- Leone Nicoletta
- Leong Faith Qi Hui
- Leppaniemi Ari
- Leroux Julien
- Leung Ka Wai
- Leusink Astrid
- Li Ka Hin Gabriel
- Licari Leo
- Lieske Bettina
- Lieske Bettina
- Liew Ignatius
- Lilford Richard
- Lilford Richard
- Lim Hui
- Lim Jieqi
- Lim Shujing Jane
- Lim Shyang Yee
- Limoges Bernard
- Lipnickas Vytautas
- Litvin Andrey
- Liu Qinyang
- Liu Qinyang
- Ljuhar Damir
- lo Conte Annalisa
- loaloa Mohamed Reda
- Lokman Muhammad Amsyar Auni
- Longstaff Lydia
- Lopez Manuel
- Lopez Manuel
- Lorenzon Laura
- Low Xinwei
- Luc Alberto Realis
- Lucia Contreras-Vergara Ana
- Luck Joshua
- Luglio Gaetano
- Lund Jonathan
- Lytras Dimitrios
- Mabitsela Matlou Ernest
- Mabrouk Mohamed
- Macchitella Yuri
- Machain Vega Gustavo Miguel
- Maciejec Laura
- Madiba Thandinkosi
- Madkor Mona Hamdy
- Madrid Barrientos Linda Alvi
- Maffioli Anna
- Magdy Ahmed
- Magdy Eman
- Magdy Hesham
- Magdy Mohamed
- Magdy Salma
- Maghrabi Ashraf
- Magri Daniela
- Mahanty Silke
- Mahdi Shareef
- Maher Mahmoud Elkhadragy
- Mahmoud Basma
- Mahmoud Farah
- Mahmoud Hend
- Mahmoud Mohamed Ali
- Mahmoud Moustafa Ibrahim
- Mahmoud Sabry Mohy Eldeen
- Mahmoud Shady
- Maillot Betty
- Maimbo Mayaba
- Maimbo Mayaba
- Mairs Nora Grace
- Maison Kwame
- Maistry Niveshni
- Majauskyte Dovile
- Majbar Anass
- Majid Aminah Hanum Haji Abdul
- Majid Kiran
- Major Piotr
- Major Piotr
- Mak T. W. C.
- Makama Jerry
- Makupe Alex
- Malaga Barbara
- Malavenda Mariastella
- Mamdouh Rana
- Manatakis Dimitrios K.
- Manfreda Serena
- Mangiapane Mirko
- Mann Thomas
- Mano Maria Jesusa B.
- Manrique Sila George Christian
- Manriquez-Reyes Marisol
- Mansor Eman Yahya
- Mansour Salma
- Mansuri Anahita
- Mao Patrizio
- Maraie Noha
- Margaritis Michail
- Maria Garcia-Perez Jose
- Mariani Aurora
- Marret Jean-Baptiste
- Mas Robinson
- Mat Tuan Nur'Azmah Tuan
- Mata Lusi Padma Sulistianingsih
- Matheu Alejandro
- Mathew Susan Wndy
- Matos-Puig Roel
- Mattar Omar
- Matter Sara Mamdouh
- Mazelyte Ruta
- Mazrimas Povilas
- Mazzella Angela
- McGarvie Susan
- McIntosh Kirsten
- Mclean Kenneth
- Mehdi Aia
- Melo Cardozo Ramon Augusto
- Melo Renato
- Mendel Henry
- Mensah Ekow
- Meqbil Jehad
- Mericliler Meric
- Merlini David
- Mesbah Nourhan
- Migliore Marco
- Mihaljevic Andre L.
- Mihanovic Jakov
- Mikalauskas Saulius
- Mikuckyte Deimante
- Mingrone Pietro
- Minguez Garcia Javier
- Minocha Ashish
- Miranda Cesar
- Mircea Hogea
- Mironescu Aurel
- Mironescu Aurel
- Mironescu Aurel Sandu
- Mirza Shahrukh
- Mitroudi Magdalini
- Mitul Ashrarur Rahman
- Miyar de Leon Alberto
- Miyasato Hector Shibao
- Mizzi Christine
- Mizzi Sean
- Moaty Mohamed
- Mochet Sylvie
- Modolo Maria Marta
- Modolo Maria Marta
- Moe Thomas Tetens
- Moghazy Mahmoud Elsayed
- Mohamed Ahmed Rabie
- Mohamed Amna
- Mohamed Amna Mamdouh
- Mohamed Arwa
- Mohamed Bakeer
- Mohamed Fawzy
- Mohamed Mazed
- Mohamed Mohamed Abdelaty
- Mohamed Shaza Rabie
- Mohammad Aminu
- Mohammed Ahmed Rabeih
- Mohammed Amany Eldosouky
- Mohammed Hussein
- Mohammed Mustafa Mohammed
- Mohammed Sara
- Mohan Midhun
- Mok Yi Ting
- Monaghan Eimear
- Monrad-Hansen Peter Wiel
- Monteleone Michela
- Monterroso Cohen David
- Montes Irene
- Montrimaite Margarita
- Moodley Yoshan
- Moore Rachel
- Mora John Jemuel V.
- Morandi Eugenio
- Morgan Catrin
- Morshedy Eman Mohamed
- Morton Dion
- Mostafa Merna
- Mostafa Mohamed
- Moussa Omar
- Moustafa Ahmed
- Mowafy Bassant
- Mshelbwala Philip
- Msiska Nelson
- Msosa Vanessa
- Msosa Vanessa
- Muddebihal Uday
- Mueller Julia
- Mukin Annisa Dewi Fitriana
- Muktar Umar
- Mukuzunga Cornelius
- Muller Cecile
- Muntean Liviu
- Murray Alice
- Murutoglu Busra
- Musleh Aseel
- Musowoya Joseph
- Mussad Ali
- Mustafa Mousa
- Musyoka Caroluce K.
- Mutabazi Alphonse Zeta
- Mutabazi Alphonse Zeta
- Mutlu Deniz
- Mutlu Vahit
- Muzio Elena
- Myers Jonathan
- Mykoniatis Ioannis
- Nadeem Najwa
- Naess Pal Aksel
- Nagy Ghada Saied
- Nahar Sayeda Nazmum
- Najjar Mohammed
- Nanthakumaran Shayanthan
- Napolitano Lena
- Narayanan Ragavan
- Narayanan Ragavan
- Nashat Mohamed
- Nashidengo Puyearashid
- Nasir Abdulrasheed
- Nasir Wan Nurul Ain Wan Mohd
- Nasr Maha
- Nassif Dima
- Natalie Hani
- Nataraja Ram
- Natili Andrea
- Navarro Andre
- Nawawi Abrar
- Nazir Mohamed
- Ndajiwo Aliyu
- Ndajiwo Aliyu
- Ndegwa Wairimu
- Ndlovu Sibongile Ruth
- Ndwambi Phumudzo
- Negoi Ionut
- Neo Ya Theng
- Nepogodiev Dmitri
- Nepogodiev Dmitri
- Nepogodiev Dmitri
- Nessa Ashrafun
- Nestorovic Milica
- Nevieraite Viktorija
- Ng James Chean Khun
- Ng Yung Kok
- Ng Zhan Herr
- Niazi Ali Khan
- Nicholson Luke
- Nikberg Maziar
- Nikoloudis Nikolaos
- Niranjan Nithya
- Nirumal Milaksh Kumar
- Niska Karoliina
- Nita Gabriela Elisa
- Nita Gabriela Elisa
- Njokanma Iloba
- Nocito Antonio
- Noor Fazlin
- Notarnicola Margherita
- Notarnicola Margherita
- Nouh Thamer
- Noukpozounkou Bruno
- Nsengiyumva Carlos
- Ntirenganya Faustin
- Nurqistan Hazmi Dwinanda
- Nwabuoku Emeka
- Nwinee Victor
- O'Connor Donal B.
- O'Higgins Roche Marcelo
- O'Neill Stephen
- O'Shea Margaret
- Occhionorelli Savino
- Odeyemi Babatunde
- Odutola Oluwatomi
- Ogunsua Oluseyi
- Ohene-Yeboah Micheal
- Okenabirhie Ogheneochuko
- Olajide Thomas Olagboyega
- Olaolorun Akin
- Olivier James
- Olori Samson
- Oludara Mobolaji
- Olugbemi Mojolaoluwa
- Omar Mohammad Elsayed
- Omar Muhammad Fathi Waleed
- Omer Omer Abdelbagi
- Onuoha Clement
- Opoku-Agyeman Richard
- Oram Shaun
- Ortega Irene
- Ortega Irene
- Ortiz Nadia
- Orton Peter
- Osagie Olabisi
- Osei-Nketiah Samuel
- Oshati Oyindamola
- Osinowo Adedapo
- Osuoji Roland
- Oswald Dennis
- Otero-Diez Jorge L.
- Ots Riinu
- Otten Kars
- Owen Christopher
- Owusu Frank
- Ozben Volkan
- Ozkan Bahar Busra
- Ozmen Berk Baris
- Padmore Greg
- Paez Lopez Larissa Ines
- Pagano Gianluca
- Pagnozz Janet
- Palayan Kandasami
- Palliyil Madanmohan
- Palma Adrian
- Paludi Miguel Angel
- Panteli Christina
- Papageorgiou Dimitrios
- Papailia Aspasia
- Papandrea Matteo
- Papaskarlatos IasonAntonios
- Pape James
- Parakh Jehangirshaw
- Paramasivan Arjun
- Parasyris Stavros
- Pardo Gabriel
- Park Esther H. G.
- Park Jay
- Parker Robert
- Parmentier Benoit
- Parpoudi Styliani
- Parseliunas Audrius
- Pascale Giovanni
- Pascale Marco Maria
- Pasquali Sandro
- Pastora Javier
- Pata Domenica
- Pata Francesco
- Pata Francesco
- Pata Francesco
- Pata Francesco
- Pata Francesco
- Pata Giacomo
- Patel Khyati
- Patel Priya
- Patel Sanjay
- Paterson-Brown Simon
- Patoulias Ioannis
- Paul Marie
- Paulouski Dzmitry
- Paz Galvez Carlos
- Pazuskis Matas
- Pektas Ahmet Murat
- Pellino Gianluca
- Peltrini Roberto
- Pena Lenin
- Perenyei Miklos
- Perera James
- Perera James
- Perez Rojas Angel David
- Perino Martina
- Peros Georgios
- Perrotta Gerardo
- Pertersen Servin Gustavo Rodolfo
- Pesenti Giovanni
- Petrikenas Steponas
- Peycelon Matthieu
- Pezas Theodore
- Picardo Antonio
- Picardo Antonio
- Picciariello Arcangelo
- Pineno-Flores Cristina
- Pinkney Thomas
- Pinkney Thomas
- Pinnagoda Kalitha
- Ploski Jennifer
- Pluke Kent
- Podevin Guillaume
- Poh Keat-Seong
- Popa Mariuca
- Popoola Ademola
- Poskus Tomas
- Poskus Tomas
- Poskus Tomas
- Post Nathan
- Prins Marloes
- Pronin Savva
- Prudhomme Thomas
- Psarianos Kyriakos
- Pugliesi Thays Brunelli
- Pujol-Cano Natalia
- Purwaningsih Nurlaila Ayu
- Puyana Juan
- Qaissieh Ahmad
- Qawasmi Israa
- Qenawy Mostafa
- Quek Roy
- Qureshi Ahmad Uzair
- Qureshi Ahmad Uzair
- Qureshi Mobeen
- Qurie Khalid
- Rackauskas Rokas
- Radkowiak Dorota
- Radojkovic Milan
- Rahantasoa Finaritra Casimir Fleur Prudence
- Rahmah Dina Faizatur
- Rajan Reynu
- Rajmohan Shivanchan
- Rakha Ibrahim
- Ramadan Menna Tallah
- Ramos Perez Virginia
- Ramos-De la Medina Antonio
- Ramos-De la Medina Antonio
- Ramos-De la Medina Antonio
- Raptis Dimitri Aristotle
- Raptis Dmitri
- Rashad Eman
- Rashed Ahmed M.
- Rasoaherinomenjanahary Fanjandrainy
- Rath Max
- Ravishankar Ramanish
- Rayne Sarah
- Rayne Sarah
- Rayne Sarah
- Rayne Sarah
- Raza Ahmed
- Raza Awais
- Raza Ibrahim
- Razuri Cesar
- Razzaque Joyeta
- Reali Claudia
- Recinos Gustavo
- Recinos Gustavo
- Reda Amira
- Reda Aya
- Redgrave Natalie
- Redota Menold Archee P.
- Reece-Smith Alex
- Reinisch Katharina
- Reinsoo Arvo
- Rekhis Syrine
- Renaux-Petel Mariette
- Restrepo Ivan Mendoza
- Reunis Elke
- Rezq Asmaa
- Riauka Romualdas
- Riaz Muhammed Masood
- Ribaldi Sergio
- Rickard Jennifer
- Rida Ahmed Hossam Eldin Fouad
- Riente Francesco
- Rinaldi Anna
- Ringressi Maria Novella
- Ripa Matteo
- Riswan Nur Zulaika
- Rob Zakaria
- Robert Elsa
- Robledo-Rabanal Alina
- Rocke Alistair
- Rod Julien
- Rod Julien
- Rodicio Joseluis
- Rodriguez Xianelle
- Roman Velasquez Armando Jose
- Romani Diego
- Romani Diego
- Rommaneh Muna
- Roodt Liana
- Rosales Javier
- Rosello Olivier
- Roslani April Camilla
- Rossi Davide
- Roszkowski Rafal
- Rotunno Giuseppe
- Rouse Tyler
- Roy Chloe
- Roy Swapnil
- Rubinkiewicz Mateusz
- Ruiz Panez Walter
- Ruiz-Tova Jaime
- Rulie Anthonius Santoso
- Runigamugabo Emmy
- Russo Alfio Alessandro
- Rutkowski Wiktor
- Ruzzenente Andrea
- Saad Abdalla Gamal
- Saad Hala
- Saad Hanan Adel
- Saad Mahmoud M.
- Saad Reham
- Saadeh Rana
- Saami Mahmoud
- Saar Sten
- Sabe Ahmad
- Sabe Ahmad Khaled
- Sabour Fahd Abdel
- Sacco Michele
- Sacco Rosario
- Saeed Manar
- Sahbaz Nuri Alper
- Sahel Sarah
- Saidbadr Ahmed
- Sakr Ahmad
- Salah Asmaa
- Salah Maram
- Salah Mohamed
- Salah Osama Mohamed
- Salama Mahmoud
- Salama Yahya
- Salamone Giuseppe
- Salcedo Jannin
- Sale Danjuma
- Saleh Amr Ahmed
- Salem Hosni Khairy
- Salem Hosni Khairy
- Salem Hosni Khairy
- Salem Menatalla
- Salem Mohammed Mousa
- Sallam Abd Elkhalek
- Salleh Afizah
- Sallinen Ville
- Salma Mahmoud
- Salma Umme
- Salman Ayman
- Salusso Paola
- Sam Zi Hao
- Samalavicius Narimantas E.
- Samison Luc Herve
- Sammarco Giuseppe
- Sammut Keith
- Samson Garba
- Samuel Sani Ali
- Samy Mostada
- Samy Mostafa
- Sanad Aly
- Sanchez Rosenberg Guillermo
- Sanchez Samaniego Camila
- Sanchez Belen
- Sanchez Diana
- Sander Anthony
- Sandler Simone
- Sandoval Barrantes Ana Maria
- Sanni Hakeem Ayomi
- Sanz Sandra
- Sapci Ipek
- Saqlain Muhammad
- Sarafilovic Hannah
- Saraste Deborah
- Saravia Fridiz
- Sasia Diego
- Saw Jian Er
- Sayed Farrag
- Sayed Marwa
- Scalabre Aurelien
- Scalabre Aurelien
- Schadde Erik
- Schiavone Roberto
- Schmid Roger
- Schmitt Francoise
- Schuetz Tobias
- Schultz Johannes Kurt
- Scicluna Ruth
- Segovia Lohse Helmut Alfredo
- Seisay Sam
- Selvaggi Francesco
- Selvaggi Lucio
- Semeda Nourhan
- Semiz Anil
- Sena-Ruiz Fatima
- Senanayake Kithsiri J.
- Setiawan Jonny
- Seto Djifid Morel
- Seyoum Nebyou
- Sfougaris Dimitrios
- Shachykava Tatsiana
- Shaharuddin Shahadatul
- Shahbaz Aized Raza
- Shaheen Alaa
- Shahine Ahmed
- Shahzad Noman
- Shaikh Nihaal
- Shakshouk Hend Adel Gawad
- Shalabi Ahmad
- Shalaby Mahmoud
- Shalaby Mostafa
- Shamasneh Ala
- Shamsedine Ahmed W.
- Sharma Abhishek
- Sharpin Claire
- Shatkar Veeranna
- Shaw Catherine A.
- Shaw Catherine A.
- Shawky Martina Yusuf
- Shawqi Muhammad
- Sheshe Abdurrahaman
- Sheta Ahmed
- Shillito Sam
- Shiwani Haaris A.
- Sholadoye Tunde
- Shrimanker Nikhita
- Shu Sebastian
- Shu Sebastian
- Shu Sebestian
- Shubianok Maryna
- Shwky Ayman
- Siaw Jia Yng
- Sierra Sebastian
- Sigurdadottir Johanna
- Sii Samuel S. Y.
- Sileri Pierpaolo
- Silvestri Vania
- Simioni Andrea
- Simutis Gintaras
- Skerritt Clare
- Slapelyte Evelina
- Sleem Ahmad Saber
- Sleem Mohamed
- Smart Neil
- Smart Neil
- Smedley Alexander
- Smith Christopher
- Sobnach Sanju
- Sokratous Arestis
- Solaini Leonardo
- Solar Garcia Lorena
- Soldevila-Verdeguer Carla
- Soledad Merlo Maria
- Soley Rafael
- Soliman Abdelrahman
- Soliman Ahmed
- Soliman Noha Abdullah
- Soliman Nourhan
- Soliman Samar
- Soliman Yasmin
- Sollazzo Viviana
- Soon Wai Cheong
- Soreide Jon Arne
- Soreide Kjetil
- Soreide Kjetil
- Souaibou Yacoubou Imorou
- Soulou Vasiliki
- Spence Richard
- Spence Richard
- Spence Richard
- Spence Richard
- Sproule Lorraine
- Srinivasan Ravi
- Sroor Fathy
- Sruogiene Elena Zdanyte
- Steccanella Francesca
- Stefanopoulos Anastasios
- Stock Simon
- Stoddart Michael
- Stoddart Michael
- Stourton Frederick
- Strupas Kestutis
- Stuva Jessica
- Styles Kristian
- Suarez Aida
- Subocius Andrejus
- Sund Malin
- Suresh Sukrit
- Sutandi Nathania
- Suyadi Arlindawati
- Swaroop Mamta
- Syibrah Khuzaimah Zahid
- Tabiri Stephen
- Tabiri Stephen
- Tabiri Stephen
- Tabiri Stephen
- Tackie Enoch
- Taddei Antonio
- Tahboub Haya
- Taher Ayman
- Taher Mustafa Mohammed
- Taieb Chouikh
- Taiwo Agboola
- Taiwo Ogechukwu
- Talaat Muhammed
- Tale Luis
- Talving Peep
- Talving Peep
- Tan Charlene
- Tan Choy Ling
- Tan Joel Kin
- Tan Keith Say Kwang
- Tan Ryan Choon Kiat
- Tan Yee Wen
- Tan Yi Koon
- Tang Lingshan
- Tani Sobhana Iftekhar
- Tansoker Ilkan
- Tarek Adham
- Tarek Dina
- Targa Simone
- Tariq Sherif
- Tata Mahadevan Deva
- Tawfik Badreldin Adel
- Tawfik Gehad
- Teasdale Ella
- Teasdale Ella
- Teasdale Ella
- Tedeschi Umberto
- Tembo Thelma
- Tennakoon Athula
- Teo Shuang Yi
- Ter Eunice Zuling
- Tew Yong Yong
- Tew Yong Yong
- Thabet Waleed
- Thalgaspitiya S. P. B.
- Theodosopoulos Theodosios
- Thollot Aurore
- Thorarinsdottir Hildur
- Thorell Anders
- Timothy Oyediran Kehinde
- Ting Jesse Ron Swire
- To Kathleen
- Tolonen Matti
- Tolotra Todisoa Emmanuella Christina
- Tomas Kadir
- Tori Sayeeda Aktar
- Toribio Orbegozo Pedro Angel
- Torrance Hew D.
- Torres Cardozo Jorge
- Torres Rodriguez Servio Tulio
- Toto Omer Faruk
- Townsend Dominic
- Trompetto Mario
- Tselos Angelos
- Tshisola Serge Kapenda
- Tugnoli Gregorio
- Tun Myint
- Turati Luca
- Turkustani Sondos
- Turpo Espinoza Kenny
- Turpo Espinoza Kevin
- Tutino Roberta
- Tverskis Zygimantas
- Tyler Robert
- Tze R. Goh Ern
- Tzikos Georgios
- Ubiali Paolo
- Ukwenya Yahaya
- ul Razi Syed Asaat
- Ulusahin Mehmet
- Upadhyaya Vijaid
- Urbonas Tomas
- Urniezius Zigmantas
- Uscinas Laimonas
- Uzabumwana Norbert
- Vaicius Arturas
- Valcarcel-Saldana Maria
- Valioulis Ioannis
- Van Der Naald Niels
- Van Niekerk Michael
- Van Straten Stephanie
- Vargas Marvin
- Vartanoglu Talar
- Vartic Mihaela
- Vasquez Giorgio
- Vasquez Idelso
- Veen Torhild
- Velasquez Ricardo
- Venclauskas Linas
- Vendramin Elena
- Venskutonis Donatas
- Venskutonis Donatas
- Verbeek Anna
- Vergara Mejia Angelica Genoveva
- Verjee Azmina
- Vermaas Maarten
- Vicario Erika
- Vicenta Collado Maria
- Vida Lucian Corneliu
- Vilcinskas Mantas
- Villalobos Santiago
- Violi Paola
- Visinskas Petras
- Voulgaris Evangelos
- Wael Noha
- Wakefield Rebecca
- Waledziak Maciej
- Walker Michael
- Walker Nathan
- Walls Luke
- Walsh Michael
- Waqar Muhammad
- Warren Oliver
- Waterman Ade
- Werder Gabriela
- Whitaker John
- White Rebecca
- Whitehurst Katharine
- Wiborg Joachim
- Widiastini T. Ariani
- Widmer Lukas Werner
- Wijayarathna L. S.
- Williams Omolara
- Wilson Ling
- Wilson Michael
- Wilson Michael
- Wimalge P. M. S. N.
- Wogensen Fredrik
- Wolf Bernhard
- Wondoh Paul
- Wondoh Paul
- Wong Chui Yee
- Wong Francisca
- Wong Hong Yee
- Wood Greta
- Worku Mengistu
- Worku Tewodros
- Wright Naomi
- Yahaya Muhammad Taqiyuddin
- Yakubu Musah
- Yam Sir Young
- Yang James
- Yap Suhhuey
- Yau Jih Dar
- Ye Joselyn
- Yeang Li Jing
- Yeung Man Hon Andrew
- Yifieyeh Abiboye
- Yildirim Reyyan
- Yip Chingwan
- Ymeri Shpetim
- Yoganathan Pigeneswaren
- Yolcu Sinem
- Yong Guo Liang
- Younis Abobaker
- Youssef Mohamed
- Yuksek Mahmut Arif
- Yusufali Taha
- Zaa'treh Rula
- Zadoroznas Antanas
- Zahran Diaaaldin
- Zakaria Esraay
- Zakaria Mahmoud
- Zakaria Yehia
- Zaki Ahmed
- Zammit Stefan
- Zampitis Nikolaos
- Zani Augusto
- Zani Augusto
- Zanini Nicola
- Zapata Felipe
- Zarb Ciskje
- Zeta Solis Ludwing Alexander
- Zielinski Martin
- Zilinskas Justas
- Zilinskas Justas
- Zilinskas Justas
- Zilinskiene Reda
- Ziubryte Greta
- Zohair Ahmed
- Zuber Markus
- Zuk Grzegorz
- Zulkifli Athirah
- Zumbuhl Lucius
- Publication venue
- Elsevier
- Publication date
- 01/06/2003
- Field of study
BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London
Global wealth disparities drive adherence to COVID-safe pathways in head and neck cancer surgery
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- Field of study
Peer reviewe
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- Yabut K.
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- Yaghi N.
- Yaghi Y.
- Yahia Mohamed Ali M.
- Yakushkina A.
- Yalcinkaya A.
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- Ylatoma Diaz E. A.
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- Younes E.
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- Yu K.
- Yue S. Y. P.
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- Yusuf B.
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- Zahra B.
- Zahran D.
- Zakaria A. D.
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- Zattoni D.
- Zavala G.
- Zawahrah H.
- Zeiton A.
- Zeko A.
- Zeng Z.
- Zeromskas P.
- Zhang G.
- Zhivkov E.
- Zid E.
- Zidan A. M.
- Zielasek C.
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- Zimmermann B.
- Ziprin P.
- Zizzo M.
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- Zoikas A.
- Zorrilla Matilla L. P.
- Zoulamoglou M.
- Zreeg D.
- Zub-Pokrowiecka A.
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- Zuhdy M.
- Zuikyte D.
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- Zulu S.
- Zumbakys
- Zupan D.
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2022
- Field of study
Background Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide.Methods A multimethods analysis was performed as part of the GlobalSurg 3 study-a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital.Findings Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3.85 [95% CI 2.58-5.75]; p<0.0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63.0% vs 82.7%; OR 0.35 [0.23-0.53]; p<0.0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer.Interpretation Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised
Durvalumab Plus Carboplatin/Paclitaxel Followed by Maintenance Durvalumab With or Without Olaparib as First-Line Treatment for Advanced Endometrial Cancer: The Phase III DUO-E Trial
- Author
- Aktas Bahriye
- Anderson Charles
- Barretina Pilar
- Baurain Jean-francois
- Bednarek Wieslawa
- Berman Tara
- Blank Stephanie
- Blank Stephanie V.
- Bourhaba Maryam
- Bradley William
- Brasiuniene Birute
- Brasiuniene Birute
- Bruchim Ilan
- Burke James
- Cabrera Luviano Jesus Elvis
- Camargo Vanessa Rosas
- Cappuccini Fabio
- Carney Michael
- Chambers Setsuko
- Chang Suk-joon
- Chen Lee-may
- Chon Hye Sook
- Chon Hye Sook
- Company Jesus Alarcon
- Congzhu Li
- Contreras Mejia Fernando
- Contreras Jessica Reyes
- Covens Allan
- Csoszi Tibor
- Da Costa Miranda Vanessa
- Danbo Wang
- De Cuypere Eveline
- De Guerke Lara
- De La Garza Joseph
- De Melo Andreia Cristina
- De Melo Andreia Cristina
- Debruyne Philip
- Del Rosario Paula Michelle
- Denys Hannelore
- Depasquale Stephen
- Devinder Paul
- Diaz Julian Rivera
- Disilvestro Paul
- Dominguez-andrade Adriana
- Donnelly Conor
- Edraki Babak
- Egger Eva
- Estevez-garcia Purificacion
- Fleming Evelyn
- Forget Frederic
- Fountzilas George
- Fox Jenny
- Frentzas Sophia
- Galvez Fernando
- Ganessan Kichendasse
- Gao Bo
- Garcia Yolanda
- Garza Joseph De La
- Ge Lou
- Gen-hai Zhu
- Gerson-cwilich Raquel
- Ghatage Prafull
- Gil-martin Marta
- Gil-martin Marta
- Gilbert Lucy
- Gold Michael
- Gold Michael A.
- Gordinier Mary
- Goyal Lovenish
- Grisan Karin
- Guedes Joao Daniel
- Guiling Li
- Gupta Sudeep
- Guy Michael
- Hamanishi Junzo
- Hartenbach Ellen
- Haygood Chisten
- Hernandez Angel Luis
- Hernandez Carlos Hernandez
- Hernandez Jesus Lopez
- Ho Wing Ming
- Hong Shi
- Hong Sook Hee
- Hong Zheng
- Hongwu Wen
- Honhon Brigitte
- Imai Yuichi
- Inciura Arturas
- Ji-hong Liu
- Jing Wang
- Jonuskiene Goda
- Joosens Eric
- Jordan Scott
- Joseph De Padua Charles Andree
- Kado Nobuhiro
- Kamiura Shoji
- Kang Sokbom
- Karageorgopoulou Sofia
- Kato Hienori
- Ke Wang
- Kilgore Larry
- Kim Byoung-gie
- Kim Jan-weon
- Kim Yong Man
- Kim Young
- Kirtbaya Dmitriy
- Klasa-mazurkiewicz Dagmara
- Klasa-mazurkiewicz Dagmara
- Kondo Eiji
- Kovel Svetlana
- Krabisch Petra
- Kreynina Julya
- Kubiatowski Tomasz
- Kudaka Wataru
- Kui Jiang
- Landherr Laszlo
- Lau Susie
- Lazaretti Nicolas
- Lee Jung-yun
- Lee Jung-yun
- Leibovici Anca
- Li Li
- Li Wang
- Lim Sheow Lei
- Lisyanskaya Alla
- Liu Ji-hong
- Liu Xiaochun
- Loen Chan Karen Kar
- Lopez Carolina Ortiz
- Lucci Joseph
- Makarova Yulia
- Martinez Lira Jose Luis
- Martinez Jeronimo
- Matsumoto Takashi
- Mattar Andre
- Mccollum Michael
- Mccollum Michael
- Mchale Michael
- Mcintyre Kristi
- Mcintyre Kristi
- Mejia Fernando Contreras
- Meniawy Tarek
- Messing Mark
- Mileshkin Linda
- Miller Eirwen
- Min Hao
- Moore Kathleen
- Moore Kathleen
- Mori Masahiko
- Moroney John
- Muller Andreas
- Naik Radheshyam
- Navarrete Aleman Jaime Esteban
- Nishikawa Tadaaki
- Nishikawa Tadaaki
- Nishio Shin
- Nishio Shin
- Novak Zoltan
- Novak Zoltan
- Nunes Joao Soares
- Okamoto Aikou
- Onstad Michaela
- Oppermann Kussler Christina Pimentel
- Orlova Rashida
- Ortiz Taylor
- Oza Amit
- Ozair Sobia
- Pacheco Carlos Javier
- Palmeiro Daniela Neves
- Papadimitriou Christos
- Papadimitriou Christos
- Papai Zsuzsanna
- Patil Tushar
- Pennington Kathryn
- Pennington Kathryn
- Pereira Jaime Rendon
- Perez Isaura Fernandez
- Pfaendler Krista
- Pirmagomedov Albert
- Poka Robert
- Potemski Piotr
- Priebe Anna
- Provencher Diane
- Psyrri Amanda
- Pustilnik Terri
- Qi Zhou
- Qinglei Gao
- Ramos Guette Pedro Luis
- Redondo-sanchez Andres
- Resnick Kimberly
- Richardson Gary
- Rom Joachim
- Roncolato Felicia
- Rose Peter
- Rosengarten Ora
- Rubini Liedke Pedro Emanuel
- Ryu Sang Young
- Saevets Valeria
- Safina Sufia
- Safra Tamar
- Salinas Erin
- Sehouli Jalid
- Sehouli Jalid
- Sekine Masayuki
- Shai Ayelet
- Shao Peng David Tan
- Sharma Sudarshan
- Sihai Liao
- Sikorska Magdalena
- Sipocz Istvan
- Skopin Pavel
- Sobol Urszula
- Soh Lay Tin
- Soliman Pamela
- Somashekhar S.p.
- Song Yong Jung
- Songling Zhang
- Sperfeld Antje
- Starks David
- Su Mien Lynette Ngo
- Sumi Toshiyuki
- Sundborg Michael
- Sundborg Michael
- Suso Juan Pablo
- Takano Hirokuni
- Takehara Kazuhiro
- Teplinsky Eleonora
- Thomes Pepin Jessica
- Thomes-pepin Jessica
- Tillmanns Todd
- Tillmanns Todd D.
- Tiscoski Katsuki Arima
- Torregroza Otero Marco Antonio
- Touhami Omar
- Tyulyandina Alexandra
- Van Nieuwenhuysen Els
- Van Nieuwenhuysen Els
- Vettus Elen
- Vieira Carolina Martins
- Villegas Tomas Sanchez
- Wang Ke
- Warshal David
- Weidong Zhao
- Westin Shannon N.
- Westin Shannon N.
- Wimberger Pauline
- Woliver Thomas
- Wu Xiaohua
- Wuliang Wang
- Yamagami Wataru
- Yin Rutie
- Ying Cheng
- Yu Zhang
- Yunokawa Mayu
- Zagour Florai
- Zhiqing Liang
- Zorr Andreas
- Publication venue
- American Society of Clinical Oncology (ASCO)
- Publication date
- 28/06/2024
- Field of study
PURPOSE Immunotherapy and chemotherapy combinations have shown activity in endometrial cancer, with greater benefit in mismatch repair (MMR)-deficient (dMMR) than MMR-proficient (pMMR) disease. Adding a poly(ADP-ribose) polymerase inhibitor may improve outcomes, especially in pMMR disease. METHODS This phase III, global, double-blind, placebo-controlled trial randomly assigned eligible patients with newly diagnosed advanced or recurrent endometrial cancer 1:1:1 to: carboplatin/paclitaxel plus durvalumab placebo followed by placebo maintenance (control arm); carboplatin/paclitaxel plus durvalumab followed by maintenance durvalumab plus olaparib placebo (durvalumab arm); or carboplatin/paclitaxel plus durvalumab followed by maintenance durvalumab plus olaparib (durvalumab + olaparib arm). The primary end points were progression-free survival (PFS) in the durvalumab arm versus control and the durvalumab + olaparib arm versus control. RESULTS Seven hundred eighteen patients were randomly assigned. In the intention-to-treat population, statistically significant PFS benefit was observed in the durvalumab (hazard ratio [HR], 0.71 [95% CI, 0.57 to 0.89]; P = .003) and durvalumab + olaparib arms (HR, 0.55 [95% CI, 0.43 to 0.69]; P < .0001) versus control. Prespecified, exploratory subgroup analyses showed PFS benefit in dMMR (HR [durvalumab v control], 0.42 [95% CI, 0.22 to 0.80]; HR [durvalumab + olaparib v control], 0.41 [95% CI, 0.21 to 0.75]) and pMMR subgroups (HR [durvalumab v control], 0.77 [95% CI, 0.60 to 0.97]; HR [durvalumab + olaparib v control] 0.57; [95% CI, 0.44 to 0.73]); and in PD-L1-positive subgroups (HR [durvalumab v control], 0.63 [95% CI, 0.48 to 0.83]; HR [durvalumab + olaparib v control], 0.42 [95% CI, 0.31 to 0.57]). Interim overall survival results (maturity approximately 28%) were supportive of the primary outcomes (durvalumab v control: HR, 0.77 [95% CI, 0.56 to 1.07]; P = .120; durvalumab + olaparib v control: HR, 0.59 [95% CI, 0.42 to 0.83]; P = .003). The safety profiles of the experimental arms were generally consistent with individual agents. CONCLUSION Carboplatin/paclitaxel plus durvalumab followed by maintenance durvalumab with or without olaparib demonstrated a statistically significant and clinically meaningful PFS benefit in patients with advanced or recurrent endometrial cancer
Global economic burden of unmet surgical need for appendicitis
- Author
- Aahlin E. K.
- Aamer A.
- Aaniana K.
- Ababneh A.
- Abaliksta T.
- Abantanga F.
- Abbas M.
- Abbasy J.
- Abbo O.
- Abbouch M.
- Abd-Elmawla M.
- Abd-Elrasoul Y.
- Abdallah E.
- Abdel-Aty A.
- Abdel-Hameed N.
- Abdel-Kader S. M.
- Abdel-Wahab N. Y. E.
- Abdelaal A.
- Abdelaty M.
- Abdelazeam A. R.
- Abdelazim G.
- Abdelaziz M. A.
- Abdelbadeai K.
- Abdelfatah A.
- AbdelFattah I.
- Abdelgelil A.
- Abdelghany S.
- Abdelhady S.
- Abdelhamed R.
- Abdelhamid A.
- Abdelhaq A.
- Abdelkader M.
- Abdelkader O.
- Abdelkareem A.
- Abdelkhalek M.
- Abdelmageed E.
- Abdelmotaleb I.
- Abdelraheim M.
- Abdelraouf A. M.
- Abdelrouf D. M.
- Abdelshafy M.
- Abdelshakour M.
- Abdrabou A. K.
- Abdul-Latif S.
- Abdulaziz H.
- Abdulbagi O.
- Abdulgawad M.
- Abdulhakeem E. M.
- Abdullah M. A.
- Abdullah N.
- Abdullah N. A. N.
- Abdullahi L.
- Abdurrazzaaq A.
- Abebe N. S.
- Abebe N. S.
- Abem O. E.
- Abiola O.
- Aboarab A.
- Aboelella M.
- Aboelmagd O.
- Aboelsoud M. R.
- Aboraya M.
- Aboraya M.
- Abouelnasr A.
- Aboul-Naga M. S.
- Abouzahra A.
- Abouzaid A.
- Abozaid M.
- Abozeid K.
- Abozyed M. A. F.
- Abu-Toyour M.
- Abubakr M.
- Abudeeb H.
- Abuowda Y.
- Abuqwaider E.
- Abusalem L.
- Abuseif M.
- Abushamleh S.
- Ackom E.
- Acquah E.
- Adam N.
- Adams R.
- Adamu A.
- Adawi I.
- Adawi M.
- Adebanjo A.
- Adebola O.
- Adedeji A.
- Adekoya A.
- Adel A.
- Adel A.
- Adel B. E.
- Adel I.
- Adella F. J.
- Adelshone A.
- Ademuyiwa A. O.
- Adenekan B.
- Adeniran J.
- Adeniyi A.
- Adesanya O.
- Adesina A.
- Adesuyi A.
- Adeyeye A.
- Adham W.
- Adhitama N.
- Adil M.
- Adisa A. O.
- Adu-Aryee N.
- Afana S.
- Afandy A.
- Afifi A. M.
- Africa S.
- Agalianos C.
- Agarwal A.
- Agbedinu K.
- Agius M.
- Aglan A.
- Aguilar W. L. M.
- Aguilar-Jimenez J.
- Aguilera M. L.
- Aguilera O.
- Aguilera-Arevalo M. -L.
- Ahlonsou G.
- Ahlqvist S.
- Ahmed A.
- Ahmed A.
- Ahmed A.
- Ahmed E. A.
- Ahmed H.
- Ahmed H.
- Ahmed H.
- Ahmed L. A. M.
- Ahmed S.
- Ahmed S.
- Ahmed S. M.
- Ahounou E. Y. S.
- Aigrain Y.
- Ajah J.
- Ajai O.
- Ajao A. E.
- Ajiboye A.
- Akatibo E.
- Akeel N.
- Akoto E.
- Al Amin S.
- Al Attar S. M.
- Al Awwad S.
- Al Barrawi F. E.
- Al Bastawis F.
- Al Meligy A.
- Al Rafati A. A. R.
- Al Raouf E. A.
- Al Saied G.
- Al Subaie N.
- Al-Aarag A. A. -R.
- Al-Azraqi I. A. A.
- Al-Buhaisi A.
- Al-Dakka E.
- Al-Faifi J. J.
- Al-Faqawi M.
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- Publication venue
- Oxford University Press
- Publication date
- 01/01/2022
- Field of study
Background: There is a substantial gap in provision of adequate surgical care in many low-and middle-income countries. This study aimed to identify the economic burden of unmet surgical need for the common condition of appendicitis. Methods: Data on the incidence of appendicitis from 170 countries and two different approaches were used to estimate numbers of patients who do not receive surgery: as a fixed proportion of the total unmet surgical need per country (approach 1); and based on country income status (approach 2). Indirect costs with current levels of access and local quality, and those if quality were at the standards of high-income countries, were estimated. A human capital approach was applied, focusing on the economic burden resulting from premature death and absenteeism. Results: Excess mortality was 4185 per 100 000 cases of appendicitis using approach 1 and 3448 per 100 000 using approach 2. The economic burden of continuing current levels of access and local quality was US 92492millionusingapproach1and73 141 million using approach 2. The economic burden of not providing surgical care to the standards of high-income countries was 95004millionusingapproach1and75 666 million using approach 2. The largest share of these costs resulted from premature death (97.7 per cent) and lack of access (97.0 per cent) in contrast to lack of quality. Conclusion: For a comparatively non-complex emergency condition such as appendicitis, increasing access to care should be prioritized. Although improving quality of care should not be neglected, increasing provision of care at current standards could reduce societal costs substantially
Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy
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- Lawal T
- Lawal TA
- Lawani I
- Lawther R
- Lazzari G
- Lazzari V
- Lazzarini Cury AD
- Le VTH
- Leal A
- Leal M
- Leanne Almanon C
- Lecompte J-F
- Lee C
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- Lee F
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- Leusink A
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- Lim G
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- Macfarlane A
- Machaca M
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- Madiba T
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- Madrid Barrientos LA
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- Manfreda S
- Mangan C
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- Mirza A
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- Mistry A
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- Moe TT
- Mogan YP
- Moghazy ME
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- Mohamed B
- Mohamed F
- Mohamed I
- Mohamed M
- Mohamed MA
- Mohamed MAEH
- Mohamed MM
- Mohamed O
- Mohamed SR
- Mohameden A
- Mohammad A
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- Mohammed A
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- Mohammed H
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- Mohammed MMH
- Mohammed S
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- Monteleone M
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- Montoya Botero JA
- Montrimaite M
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- Mosalum O
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- Mostafa M
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- Sokratous A
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- Solar Garcia L
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- Soldevila-Verdeguer C
- Soley R
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- Taha EMS
- Tahboub H
- Taher AA
- Taher M
- Taher MM
- Taieb C
- Taiwo A
- Taiwo O
- Taiwo O
- Talaat M
- Tale F
- Tale L
- Talukder S
- Talukder S
- Talving P
- Talving P
- Tammam A
- Tan C
- Tan CL
- Tan CY
- Tan JJ
- Tan JK
- Tan KSK
- Tan RCK
- Tan YK
- Tan YW
- Tanase A
- Tanase A
- Tang A
- Tang L
- Tani SI
- Tansoker I
- Tarek A
- Tarek A
- Tarek D
- Targa S
- Tariq S
- Tata MD
- Tatagiba LS
- Tawfik BA
- Tawfik G
- Tawfik G
- Taylor F
- Teasdale E
- Teasdale E
- Teasdale E
- Teasdale E
- Tedeschi U
- Tedjaatmadja C
- Telfah MM
- Tembo T
- Temoche E
- Tennakoon A
- Teo SY
- Ter EZ
- Tessera G
- Teufelberger G
- Tew YY
- Tew YY
- Tewari S
- Th'ng F
- Thabet W
- Thalgaspitiya SPB
- Tham JC
- Thanusan V
- Tharmalingam S
- Theodosopoulos T
- Thollot A
- Thomas E
- Thomas HS
- Thompson B
- Thomson P
- Thorarinsdottir H
- Thorarinsdottir H
- Thorell A
- Thorell A
- Thorsen K
- Thurairaja R
- Tierney G
- Tilston TW
- Timothy OK
- Ting JRS
- To K
- To K
- Todd KO
- Toeema AG
- Tolba H
- Tolg C
- Tolonen M
- Tolotra TEC
- Tomas K
- Tori SA
- Toribio Orbegozo PA
- Torrance HD
- Torrance HD
- Torres Cardozo J
- Toto OF
- Tou S
- Townsend D
- Tracy J
- Trompetto M
- Tselos A
- Tshisola SK
- Tugnoli G
- Tugnoli G
- Tun AK
- Tun M
- Tun M
- Turati L
- Turati L
- Turkustani S
- Turner M
- Turpo Espinoza K
- Turpo Espinoza K
- Tutino R
- Tverskis Z
- Tyler R
- Tyler R
- Tze RGE
- Tze RGE
- Tzikos G
- Ubhi HK
- Ubiali P
- Ugalde P
- Ukwenya Y
- Ulusahin M
- Upadhyaya V
- Upchurch E
- Urbanavicius L
- Urbina Rojas NM
- Urbonas T
- Urbonas T
- Urniezius Z
- Urniezius Z
- Usaityte A
- Uscinas L
- Utter M
- Uzabumwana N
- Vaicius A
- Valcarcel-Saldana M
- Valente Laufer LA
- Valioulis I
- Van Der Naald N
- Van Duren B
- Van Niekerk M
- Van Straten S
- Varcada M
- Vargas M
- Varkalys K
- Vartanoglu T
- Vartic M
- Vartic M
- Vasquez G
- Vasquez I
- Veen T
- Velasquez R
- Vella-Baldacchino M
- Venclauskas L
- Vendramin E
- Venskutonis D
- Venskutonis D
- Venskutonis D
- Venskutonis D
- Venugopal C
- Verbeek A
- Vergara Celis JM
- Vergara Mejia AG
- Verjee A
- Vermaas M
- Veronese E
- Vianna JGP
- Vicario E
- Vicenta Collado M
- Vida LC
- Vida LC
- Vilcinskas M
- Villa R
- Villalobos S
- Vimalachandran D
- Vincent J
- Violi P
- Visinskas P
- Vivekanantham S
- Vlachogiorgos A
- Voulgaris E
- Wael N
- Wagener M
- Wakefield R
- Waledziak M
- Waleed H
- Walker M
- Walker N
- Walls L
- Walsh M
- Walsh U
- Waqar M
- Ward AE
- Ward S
- Warda M
- Warren O
- Warren O
- Warwick AM
- Waterman A
- Watson NF
- Watson NF
- Watts A
- Weber B
- Weber P
- Weber P
- Weinstein MS
- Weiser TG
- Werder G
- Wheeler J
- Whewell H
- Whitaker J
- White R
- White T
- Whitehurst K
- Wiborg J
- Widiastini TA
- Widmer LW
- Wijayarathna LS
- Wild JRL
- Williams E
- Williams G
- Williams O
- Williams O
- Williamson A
- Wilson A
- Wilson L
- Wilson M
- Wilson M
- Wilson MSJ
- Wilson MSJ
- Wimalge PMSN
- Winstanley J
- Witherspoon P
- Wogensen F
- Wogensen F
- Wogensen F
- Woin E
- Wold TB
- Wolf B
- Wolf B
- Wondimu S
- Wondoh P
- Wondoh P
- Wong CS
- Wong CY
- Wong F
- Wong HY
- Wood G
- Woodward H
- Worku M
- Worku M
- Worku T
- Wredberg C
- Wright N
- Wright NJ
- Xerri T
- Xerri T
- Yahaya MT
- Yakubu M
- Yallop L
- Yam SY
- Yang J
- Yap S
- Yaseen T
- Yaseen TM
- Yau JD
- Yavuz MA
- Ye J
- Yeang LJ
- Yee J
- Yeo LS
- Yeung ENW
- Yeung MHA
- Yifieyeh A
- Yildirim R
- Yip C
- Ymeri S
- Yoganathan P
- Yolcu S
- Yong CO
- Yong GL
- Younis A
- Youssef D
- Youssef H
- Youssef M
- Youssif JH
- Yuksek MA
- Yusufali T
- Zaa'treh R
- Zachariades D-C
- Zadoroznas A
- Zahran D
- Zakaria E
- Zakaria M
- Zakaria Y
- Zaki A
- Zakir M
- Zalabia MF
- Zamarin K
- Zammit S
- Zampitis N
- Zani A
- Zani A
- Zani A
- Zanini N
- Zanini N
- Zapata Ponze De Leon M
- Zapata Ponze De Leon M
- Zapata F
- Zarb C
- Zardab A
- Zegarra S
- Zeidan S
- Zelada Alvarez II
- Zerihun AB
- Zeta Solis LA
- Zhang Z
- Zheng F
- Zidan H
- Zidan H
- Zidan M
- Zielinski M
- Ziff O
- Zikry M
- Zil-E-Ali A
- Zilinskas J
- Zilinskas J
- Zilinskas J
- Zilinskas J
- Zilinskas J
- Zilinskiene R
- Zilinskiene R
- Zimmermann EF
- Ziubryte G
- Zohair A
- Zorrilla CD
- Zuber M
- Zuber M
- Zuk G
- Zulkifli A
- Zumbuhl L
- Publication venue
- Publication date
- 15/10/2018
- Field of study
Background The World Health Organization (WHO) Surgical Safety Checklist has fostered safe practice for 10 years, yet its place in emergency surgery has not been assessed on a global scale. The aim of this study was to evaluate reported checklist use in emergency settings and examine the relationship with perioperative mortality in patients who had emergency laparotomy. Methods In two multinational cohort studies, adults undergoing emergency laparotomy were compared with those having elective gastrointestinal surgery. Relationships between reported checklist use and mortality were determined using multivariable logistic regression and bootstrapped simulation. Results Of 12 296 patients included from 76 countries, 4843 underwent emergency laparotomy. After adjusting for patient and disease factors, checklist use before emergency laparotomy was more common in countries with a high Human Development Index (HDI) (2455 of 2741, 89.6 per cent) compared with that in countries with a middle (753 of 1242, 60.6 per cent; odds ratio (OR) 0.17, 95 per cent c.i. 0.14 to 0.21, P <0001) or low (363 of 860, 422 per cent; OR 008, 007 to 010, P <0.001) HDI. Checklist use was less common in elective surgery than for emergency laparotomy in high-HDI countries (risk difference -94 (95 per cent c.i. -11.9 to -6.9) per cent; P <0001), but the relationship was reversed in low-HDI countries (+121 (+7.0 to +173) per cent; P <0001). In multivariable models, checklist use was associated with a lower 30-day perioperative mortality (OR 0.60, 0.50 to 073; P <0.001). The greatest absolute benefit was seen for emergency surgery in low- and middle-HDI countries. Conclusion Checklist use in emergency laparotomy was associated with a significantly lower perioperative mortality rate. Checklist use in low-HDI countries was half that in high-HDI countries.Peer reviewe
Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study
- Author
- Aahlin Eirik Kjus
- Aamer Ahmed
- Aaniana Kenneth
- Ababneh Ali
- Abaliksta Tomas
- Abantanga Francis
- Abbas Athar
- Abbasy Jibran
- Abbo Olivier
- Abbott Tom
- Abbouch Meryem
- Abd El-Latif Nadia Khalid
- Abd Elkhalek Esraa
- Abd-Elmawla Manar
- Abdallah Emad
- Abdel-Aty Abdulrahman
- Abdel-Hameed Noran
- Abdel-Kader Sara Mahmoud
- Abdelaal Abdelaziz
- Abdelaty Mohamed
- Abdelazeam Anan Rady
- Abdelazim Galaleldin
- Abdelaziz Mohamed A
- Abdelbadeai Kholoud
- Abdelfatah Afnan
- Abdelhady Samar
- Abdelhamed Rasha
- Abdelhamid Amina
- Abdelhaq Aram
- Abdelkader Mostafa
- Abdelkader Omar
- Abdelkhalek Mohamed
- Abdelmageed Eman
- Abdelmotaleb Ibrahem
- Abdelraouf Ahmed Mahmoud
- Abdelrouf Doaa Maher
- Abdelshakour Mahmoud
- Abdrabou Abdulshafi Khaled
- Abdul-Latif Saiba
- Abdulaziz Hager
- Abdulaziz Mustafa
- Abdulbagi Omar
- Abdulhakeem Eman Mahmoud
- Abdullah Mohamed Abozed
- Abdullah Nik Azim Nik
- Abdullah Noha
- Abdullahi Lawal
- Abdurrazzaaq Abdussemiu
- Abem Owusu Emmanuel
- Abiola Olajide
- Aboelella Majed
- Aboelmagd Omnia
- Aboelsoud Moustafa R
- Aboul-Naga Mariam Saad
- Abouzaid Arwa
- Abu Qumbos Amjad
- Abu-toyour Maram
- Abubakr Marwan
- Abuowda Yousef
- Abuqwaider Eman
- Abusalem Lana
- Abushamleh Soha
- Ackom Eric
- Acquah Emmanuel
- Adam Ali
- Adam Nourhan
- Adamu Ahmed
- Adawi Ihdaa
- Adawi Mohammad
- Adebanjo Ademola
- Adebola Oluwaseyi
- Adedeji Adesina
- Adel Badr Eldin
- Adel Israa
- Adella Fidelis Jacklyn
- Adelshone Abdelrahman
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji O
- Ademuyiwa Adesoji O
- Adenekan Babajide
- Adeniran James
- Adeniyi Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adeyeye Ademola
- Adeyeye Ademola
- Adhitama Novia
- Adil Muhammad
- Adisa Adewale O
- Adiyaman Can
- Adu-Aryee Niiarmah
- Afana Samah
- Agalianos Christos
- Agarwal Arnav
- Agarwal Arnav
- Agbedinu Kwabena
- Aglan Amro
- Aguado Suarez Nuria
- Aguilera Maria Lorena
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlonsou Germain
- Ahlqvist Sandra
- Ahlqvist Sandra
- Ahmed Asdaq
- Ahmed Ataa
- Ahmed Hayam
- Ahmed Hussien
- Ahmed Lopna Ahmed Mohamed
- Ahmed Sara
- Ahmed Saraibrahim
- Ahounou Ernest Yemalin Stephane
- Ajah Jonathan
- Ajai Olalekan
- Ajao Akinlabi
- Ajiboye Anthony
- Akoto Elliot
- Akpenyi Onyinye
- Al Amin Shadid
- Al Attar Samaa Mahmoud
- Al Barraw Fayez Elian
- Al Bastawis Fatema
- Al Meligy Amgad
- Al Rafati Ahmad Abdel Razaq
- Al Raouf Eman Abd
- Al Saied Ghiath
- Al Subaie Norah
- Al-Bahrani Ahmed
- Al-Buhaisi Alaa
- Al-Dakka Emad
- Al-faqawi Maha
- Al-farram Hadeel
- Al-khatib Ahmed
- Al-Marakby Dina
- Al-saqqa Sara
- Al-Saqqa Sara W
- Al-Slaibi Ibrahim
- Al-taher Taher
- AlaaelDein Shahinaz
- Alada Muslimat
- Alakaloko Felix
- Alaloul Enas
- Alamin Shadid
- Alamoudi Mohammed
- Albiety Adel
- Alcca Ticona Willy
- Alejos Bermudez Ysabel Esthefany
- Alexander Philip
- Alexander Philip
- Alexandre Challine
- Alghamdi Ahmed
- Alghamdi Mohammed Saleh A
- Alhady Khaled
- Alhammali Tariq
- Alhassan Basmah
- Alhazmi Wedyan
- Alherz Mohammad
- Ali Ahmed
- Ali Citra Dewi Mohd
- Ali Elsayed
- Ali Safia
- Ali Syed Abdul Wahhab Eusoffee Wan
- Ali Tebian Hassanein Ahmed
- Ali Wadah
- Alihonou Thierry
- Alis Halil
- Aliyu Halima
- Aliyu Mohammad
- Aliyu Shamsudeen
- Aljboor Khaled
- Aljiffry Murad
- Alkaaki Aroub
- Alkelani Muhammad
- Allam Meran
- Allam Yomna
- Alnaby Mohamed Hassab
- Alnusairat Aseel
- Alqahtani Saleh
- Alsaggaf Mohammed Ubaid
- Alser Osaid H
- Alshareef Reham
- Altaf Abdulmalik
- Altamimi Abdullah
- Altamimi Afnan
- Altamini Afnan
- Altarayra Marwa
- Altibi Ahmed
- Altinel Yuksel
- Altinel Yuksel
- Altwijri Abdulaziz
- Alvi Abdul Rehman
- Aly Mohammed Yahia Mohamed
- Alyacoubi Said
- Alyahya Reem
- Alzahrani Ahmed
- Aman Nowrin F
- Amandito Radhian
- Amandito Radhian
- Ambrona-Zafra David
- Amin Hager Abdul Aziz
- Amjad Mohammadasim
- Amoah Michael
- Amoako Joachim
- Amoako Philip Taah
- Amoako-Boateng Mabel
- Amole Isaac
- Amreia Mahmoud
- Anderson Frank
- Andika Ferry Fitriya Ayu
- Andreotti Dario
- Andress Cedar
- Andriola Valeria
- Ang Yun Lin
- Angelieri Daniele
- Anis Echaieb
- Ansaloni Luca
- Ansaloni Luca
- Ansaloni Luca
- Antezana Diego
- Anthoulakis Christos
- Antoniozzi Angelo
- Anwar Nourhan
- Anyanwu Lofty-John
- Aonzo Paolo
- Appeadu-Mensah William
- Appiah Eric Kofi
- Aquilino Fabrizio
- Arafa Omar
- Arafa Sara
- Arango Maria Clara Mendoza
- Arcudi Claudio
- Armellini Andrea
- Arnaud Alexis
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- Arshad Mohammad Mohsin
- Arslan Ekin
- Arsyad Hasbi Maulana
- Arthur Tom
- Aruldas Neerav
- Asar Yomna Hosny
- Asare-Bediako Kwasi
- Ashour Ahmad
- Ashour Ahmad
- Ashour Khlood
- Ashtari Morvarid
- Asi Fatema
- Asilah Siti Mohd Desa
- Assal Abdelrahman
- Asturias Sabrina
- Asumah Hamza
- Ata Ahmed
- Ata Aya Yehia
- Atiyeh Anwar
- Atkins Ebenezer Takyi
- Attia Attia
- Augestad Knut Magne
- Aviles Susan
- Avoka Anthony
- Awad Israa
- Awad Sawsan Adel
- Awadallah Salwa
- Ayandipo Omobolaji
- Aydin Mehmet Can
- Aziz Dayang Nita Abdul
- Aziz Mohamed Rezal Abdul
- Aziz Nora Abdul
- Azizeldine Mohammed G
- Azzie Georges
- Azzis Olivier
- Baba Suleiman
- Bachri Houda
- Badawy Mahmoud
- Badenjki Mohamed Adel
- Badicel Maria
- Badr Mohamed Fawzy Mahrous
- Badwi Nermin Mohamed
- Bahar Suraya
- Baillie Katie
- Baki Bahadir Emre
- Bakr Ahmad
- Bakry Hesham Mohammed
- Bala Miklosh
- Balalis Dimitrios
- Balducci Genoveffa
- Ballouhey Quentin
- Balmaceda Ruben
- Balmaceda Ruben
- Balogun Fatai
- Baltrunas Robertas
- Baluch Fatima
- Bamford Rebecca
- Bamicha Athanasia
- Banaitis Vincas Jonas
- Bandi Ashwath
- Bandoh Dickson
- Bani-Sadar Ahmad
- Banipal Gurpreet Singh
- Baquero Suarez Alibeth Andres
- Baraka Heba
- Barendegere Venerand
- Barkolias Christos
- Barmayehvar Behrad
- Barnabas Gandau Naa
- Barrios Emmanuel
- Basilico Silvia
- Basir Elissa Rifhan Mohd
- Bassem Monica
- Bassit Khalil Abdul
- Basso Stefano MM
- Bayram Sefa
- Beamon Mieshia
- Bedada Alemayehu Ginbo
- BediakoBowan Antoinette
- Bekhet Amira Hassan
- Bekhet Nada Mohamed
- Beleno Alvaro Enrique Mendoza
- Belkouchi Abdelkader
- Belli Andrea
- Bello Bashir
- Benammi Sarah
- Benevento Angelo
- Bennai Redouane Mammar
- Bentounsi Zineb
- Benyaiche Chaymae
- Berti Stefano
- Bertuello Isaac
- Beuran Mircea
- Bhangu Aneel
- Bhangu Aneel
- Bhangu Anna
- Bhatnagar Ankur
- Bhopal Kamran Faisal
- Bianco Federica
- Bigaran Annamaria
- Billy Matthew
- Bin Adnan Ahmad
- Bin Hasnan Muhammad
- Bin Ismail Mohamad Jeffrey
- Birindelli Arianna
- Bisset Carly
- Bjorklund Ida
- Blacker Sarah
- Blackwell James
- Blanco Ruth
- Blanco-Colino Ruth
- Blencowe Natalie
- Bliksoen Marte
- Bluelle Rafael
- Bocchetti Tommaso
- Bode Chris
- Bodur Selim
- Boggon Adam
- Bonavia Karl
- Bonavina Luigi
- Bond-Smith Giles
- Bondin John
- Bondurri Andrea
- Boni Silvia
- Bonney William
- Borda-Luque Giuliano
- Borg Elaine
- Borg Elaine
- Bortolasi Luca
- Bottini Corrado
- Bougard Heather
- Boukhal Khaoula
- Bowabsak Alaa
- Bowling Kirk
- Bradulskis Saulius
- Bratu Matei
- Bratu Matei Razvan
- Breaud Jean
- Breistrand Michaela
- Breslin Ryan
- Brincat Svetlana Doris
- Broch Aline
- Brunoni Beatrice
- Bsisu Isam
- Bucci Luigi
- Buisson Philippe
- Bunting David
- Burger Sule
- Burmistrovas Andrius
- Bustangi Nasir
- Bustangi Nasir
- Butt Muhammad Talha
- Cakaloglu Haluk Cem
- Caliman Celeste
- Callan Rory
- Camilleri Georgette Marie
- Camilleri-Brennan Julian
- Campagnaro Tommaso
- Canta Calua Alexander
- Capito Carmen
- Carabott Kurt
- Carmela Lapitan Marie
- Carmona Juan Manuel
- Carpio Juan
- Carrasco Nahilia
- Cassar Kristina
- Catani Marco
- Cautiero Roberto
- Caydiid Hanaan
- Cecilia Tolg
- Celik Saban
- Cengiz Turgut Bora
- Cengiz Yucel
- Cengiz Yucel
- Cevik Muazzez
- Chabok Abbas
- Chai Chu-Ann
- Chai Feng Yih
- Chan Luke
- Chan Tsz-Yan Katie
- Chan Xue Wei
- Charles Angeline
- Cheah Alvin Ee Zhiun
- Chen Kar Yan
- Chen Tzu-Ling
- Cheong Yih Jeng
- Chetta Nicola
- Cheung Yuk Hong Eric
- Chibuye Chali
- Chiesa Deborah
- Chilton Gareth
- Chin Pui Xin
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- Chiu Seehui
- Choi Philip
- Chong Choon Seng
- Chong Hoong-Yin
- Choudhry Asad
- Chow Crystal Yern Nee
- Chowdhury Debkumar
- Chu Kathryn
- Chung Kuet Jun
- Chungui Bravo Jorge Armando
- Ciccioli Eleonora
- Ciubotaru Cezar
- Claire Raquillet
- Clarissa Audrey
- Clegg-Lampety Joe-Nat
- Clegg-Lamptey Joe-Nat
- Clerico Giuseppe
- Coccolini Federico
- Coccolini Federico
- Cocorullo Gianfranco
- Cohen Fraser
- Cole Simon
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- Collaborative GlobalSurg
- Cona Camilla
- Conci Simone
- Confalonieri Gianmaria
- Conlon Kevin C
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- Corbellini Carlo
- Corbellino Mario
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- Cox Daniel
- Cox Michael
- Coyoy-Gaitan Otto
- Craus-Miguel Andrea
- Cullen Fraser
- Curletti Gianluca
- Currow Chelise
- D'Amours Scott
- D'Souza Michelle S
- Dabboor Majd
- Dabbour Kareem
- Dagoe Enoch
- Dahy Ahmed
- Dainius Edvinas
- Dakubo Jonathan
- Dalli Jeffrey
- Dally Charles
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- Daniyan Muhammad
- Danys Donatas
- Dao Weihei
- Dar Wasim
- Dardenne Sabrina
- Darwish Abdelrhman KZ
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- Davor Anthony
- Dawood Khaled
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- Deal Rebecca
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- Delforge Xavier
- Dell Angela
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- Dorani Radin Mohd Nurrahman Radin
- Dorisme Asnel
- Dossou Francis
- Dousset Bertrand
- Dragatas Deividas
- Drake Thomas M
- Drake Thomas M
- Drungilas Mantas
- du Plooy Flip
- Du Toit Frederick
- Duane Therese
- Duinhouwer Lucia
- Dulskas Audrius
- Ebidy Mai
- Ebidy Mai Mohamed
- Eid Mostafa Mahmoud
- El Dahab Ali Abo
- El Gendy Noran Halim
- El Halawany Mohamed
- El Jamassi Alaa
- El Kashash Ahmed
- El Sayed Islam Magdy
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- Eldin Mostafa Ahmed Bahaa
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- Elgendy Alyaa Halim
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- Elhusseiny Ahmed Abd Elmoen
- Elkholy Shimaa Said
- Ellison Quinn
- Elmashala Amjad
- Elmasry Maha
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- Elnagar Ahmedglal
- Elnajjar Mahmoud A
- Elrazek Aly Abd
- Elsabbagh Nourhan
- Elsameea Ahmed Abd
- Elsawy Amira
- Elsayed Nada Ahmed Reda
- Elsemelawy Rofida
- Elshaar Mohammed
- Elshaer Mohamed
- Elshami Mohamedraed
- Elsharkawy Aya Adel
- Elsherbiney Saged
- Elsherif Fawzia Abdellatif
- Elwy Eman
- Elzahed Nada
- Emadeldin Hossam
- Emara Eman
- Emile Sameh
- Eng Calvin
- English William
- Esam Abeer
- Escalante Salas Marilia Del Carmen
- Espin-Basany Eloy
- Espinoza Fernando
- Essam AA
- Essam Ahmed
- Essam Mahitab
- Essoun Samuel
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- Sfougaris Dimitrios
- Shachykava Tatsiana
- Shaharuddin Shahadatul
- Shahbaz Aized Raza
- Shaheen Alaa
- Shahine Ahmed
- Shahzad Noman
- Shaikh Nihaal
- Shakshouk Hend Adel Gawad
- Shalabi Ahmad
- Shalaby Mahmoud
- Shalaby Mostafa
- Shamasneh Ala
- Shamsedine Ahmed W
- Sharma Abhishek
- Sharpin Claire
- Shatkar Veeranna
- Shaw Catherine A
- Shaw Catherine A
- Shawky Martina Yusuf
- Shawqi Muhammad
- Sheshe Abdurrahaman
- Sheta Ahmed
- Shillito Sam
- Shiwani Haaris A
- Sholadoye Tunde
- Shrimanker Nikhita
- Shu Sebastian
- Shu Sebastian
- Shu Sebestian
- Shubianok Maryna
- Shwky Ayman
- Siaw Jia Yng
- Sierra Sebastian
- Sigurdadottir Johanna
- Sii Samuel SY
- Sileri Pierpaolo
- Silvestri Vania
- Simioni Andrea
- Simutis Gintaras
- Skerritt Clare
- Slapelyte Evelina
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- Sleem Mohamed
- Smart Neil
- Smart Neil
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- Smith Christopher
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- Soliman Abdelrahman
- Soliman Ahmed
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- Soliman Nourhan
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- Sollazzo Viviana
- Soon Wai Cheong
- Soreide Jon Arne
- Soreide Kjetil
- Soreide Kjetil
- Souaibou Yacoubou Imorou
- Soulou Vasiliki
- Spence Richard
- Spence Richard
- Spence Richard
- Spence Richard
- Sproule Lorraine
- Srinivasan Ravi
- Sroor Fathy
- Sruogiene Elena Zdanyte
- Steccanella Francesca
- Stefanopoulos Anastasios
- Stock Simon
- Stoddart Michael
- Stoddart Michael
- Stourton Frederick
- Strupas Kestutis
- Stuva Jessica
- Styles Kristian
- Suarez Aida
- Subocius Andrejus
- Sund Malin
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- Sutandi Nathania
- Suyadi Arlindawati
- Swaroop Mamta
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- Tabiri Stephen
- Tabiri Stephen
- Tabiri Stephen
- Tackie Enoch
- Taddei Antonio
- Tahboub Haya
- Taher Ayman And
- Taher Mustafa Mohammed
- Taieb Chouikh
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- Taiwo Ogechukwu
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- Tale Luis
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- Talving Peep
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- Tawfik Gehad
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- Teasdale Ella
- Teasdale Ella
- Tedeschi Umberto
- Tembo Thelma
- Tennakoon Athula
- Teo Shuang Yi
- Ter Eunice Zuling
- Tew Yong Yong
- Tew Yong Yong
- Thabet Waleed
- Thalgaspitiya SPB
- Theodosopoulos Theodosios
- Thollot Aurore
- Thorarinsdottir Hildur
- Thorell Anders
- Timothy Oyediran Kehinde
- Ting Jesse Ron Swire
- To Kathleen
- Tolonen Matti
- Tolotra Todisoa Emmanuella Christina
- Tomas Kadir
- Tori Sayeeda Aktar
- Toribio Orbegozo Pedro Angel
- Torrance Hew D
- Torres Cardozo Jorge
- Torres Rodriguez Servio Tulio
- Toto Omer Faruk
- Townsend Dominic
- Trompetto Mario
- Tselos Angelos
- Tshisola Serge Kapenda
- Tugnoli Gregorio
- Tun Myint
- Turati Luca
- Turkustani Sondos
- Turpo Espinoza Kenny
- Turpo Espinoza Kevin
- Tutino Roberta
- Tverskis Zygimantas
- Tyler Robert
- Tze R Goh Ern
- Tzikos Georgios
- Ubiali Paolo
- Ukwenya Yahaya
- ul Razi Syed Asaat
- Ulusahin Mehmet
- Upadhyaya Vijaid
- Urbonas Tomas
- Urniezius Zigmantas
- Uscinas Laimonas
- Uzabumwana Norbert
- Vaicius Arturas
- Valcarcel-Saldana Maria
- Valioulis Ioannis
- Van Der Naald Niels
- Van Niekerk Michael
- Van Straten Stephanie
- Vargas Marvin
- Vartanoglu Talar
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- Vasquez Idelso
- Veen Torhild
- Velasquez Ricardo
- Venclauskas Linas
- Vendramin Elena
- Venskutonis Donatas
- Venskutonis Donatas
- Verbeek Anna
- Vergara Mejia Angelica Genoveva
- Verjee Azmina
- Vermaas Maarten
- Vicario Erika
- Vicenta Collado Maria
- Vida Lucian Corneliu
- Vilcinskas Mantas
- Villalobos Santiago
- Violi Paola
- Visinskas Petras
- Voulgaris Evangelos
- Wael Noha
- Wakefield Rebecca
- Waledziak Maciej
- Walker Michael
- Walker Nathan
- Walls Luke
- Walsh Michael
- Waqar Muhammad
- Warren Oliver
- Waterman Ade
- Werder Gabriela
- Whitaker John
- White Rebecca
- Whitehurst Katharine
- Wiborg Joachim
- Widiastini T Ariani
- Widmer Lukas Werner
- Wijayarathna LS
- Williams Omolara
- Wilson Ling
- Wilson Michael
- Wilson Michael
- Wimalge PMSN
- Wogensen Fredrik
- Wolf Bernhard
- Wondoh Paul
- Wondoh Paul
- Wong Chui Yee
- Wong Francisca
- Wong Hong Yee
- Wood Greta
- Worku Mengistu
- Worku Tewodros
- Wright Naomi
- Yahaya Muhammad Taqiyuddin
- Yakubu Musah
- Yam Sir Young
- Yang James
- Yap Suhhuey
- Yau Jih Dar
- Ye Joselyn
- Yeang Li Jing
- Yeung Man Hon Andrew
- Yifieyeh Abiboye
- Yildirim Reyyan
- Yip Chingwan
- Ymeri Shpetim
- Yoganathan Pigeneswaren
- Yolcu Sinem
- Yong Guo Liang
- Younis Abobaker
- Youssef Mohamed
- Yuksek Mahmut Arif
- Yusufali Taha
- Zaa'treh Rula
- Zadoroznas Antanas
- Zahran Diaaaldin
- Zakaria Esraay
- Zakaria Mahmoud
- Zakaria Yehia
- Zaki Ahmed
- Zammit Stefan
- Zampitis Nikolaos
- Zani Augusto
- Zani Augusto
- Zanini Nicola
- Zapata Felipe
- Zarb Ciskje
- Zeta Solis Ludwing Alexander
- Zielinski Martin
- Zilinskas Justas
- Zilinskas Justas
- Zilinskas Justas
- Zilinskiene Reda
- Ziubryte Greta
- Zohair Ahmed
- Zuber Markus
- Zuk Grzegorz
- Zulkifli Athirah
- Zumbuhl Lucius
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2018
- Field of study
Background: Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global health priority is not fully understood. We quantified the burden of SSI after gastrointestinal surgery in countries in all parts of the world.
Methods: This international, prospective, multicentre cohort study included consecutive patients undergoing elective or emergency gastrointestinal resection within 2-week time periods at any health-care facility in any country. Countries with participating centres were stratified into high-income, middle-income, and low-income groups according to the UN's Human Development Index (HDI). Data variables from the GlobalSurg 1 study and other studies that have been found to affect the likelihood of SSI were entered into risk adjustment models. The primary outcome measure was the 30-day SSI incidence (defined by US Centers for Disease Control and Prevention criteria for superficial and deep incisional SSI). Relationships with explanatory variables were examined using Bayesian multilevel logistic regression models. This trial is registered with ClinicalTrials.gov, number NCT02662231.
Findings: Between Jan 4, 2016, and July 31, 2016, 13 265 records were submitted for analysis. 12 539 patients from 343 hospitals in 66 countries were included. 7339 (58·5%) patient were from high-HDI countries (193 hospitals in 30 countries), 3918 (31·2%) patients were from middle-HDI countries (82 hospitals in 18 countries), and 1282 (10·2%) patients were from low-HDI countries (68 hospitals in 18 countries). In total, 1538 (12·3%) patients had SSI within 30 days of surgery. The incidence of SSI varied between countries with high (691 [9·4%] of 7339 patients), middle (549 [14·0%] of 3918 patients), and low (298 [23·2%] of 1282) HDI (p < 0·001). The highest SSI incidence in each HDI group was after dirty surgery (102 [17·8%] of 574 patients in high-HDI countries; 74 [31·4%] of 236 patients in middle-HDI countries; 72 [39·8%] of 181 patients in low-HDI countries). Following risk factor adjustment, patients in low-HDI countries were at greatest risk of SSI (adjusted odds ratio 1·60, 95% credible interval 1·05–2·37; p=0·030). 132 (21·6%) of 610 patients with an SSI and a microbiology culture result had an infection that was resistant to the prophylactic antibiotic used. Resistant infections were detected in 49 (16·6%) of 295 patients in high-HDI countries, in 37 (19·8%) of 187 patients in middle-HDI countries, and in 46 (35·9%) of 128 patients in low-HDI countries (p < 0·001).
Interpretation: Countries with a low HDI carry a disproportionately greater burden of SSI than countries with a middle or high HDI and might have higher rates of antibiotic resistance. In view of WHO recommendations on SSI prevention that highlight the absence of high-quality interventional research, urgent, pragmatic, randomised trials based in LMICs are needed to assess measures aiming to reduce this preventable complication
Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.
- Author
- Abate Degu
- Abate Kalkidan Hassen
- Abay Solomon M
- Abbafati Cristiana
- Abbasi Nooshin
- Abbastabar Hedayat
- Abd-Allah Foad
- Abdela Jemal
- Abdelalim Ahmed
- Abdollahpour Ibrahim
- Abdulkader Rizwan Suliankatchi
- Abebe Zegeye
- Abera Semaw F
- Abil Olifan Zewdie
- Abraha Haftom Niguse
- Abu-Raddad Laith Jamal
- Abu-Rmeileh Niveen M E
- Accrombessi Manfred Mario Kokou
- Acharya Dilaram
- Acharya Pawan
- Ackerman Ilana N
- Adamu Abdu A
- Adebayo Oladimeji M
- Adekanmbi Victor
- Adetokunboh Olatunji O
- Adib Mina G
- Adsuar Jose C
- Afanvi Kossivi Agbelenko
- Afarideh Mohsen
- Afshin Ashkan
- Agarwal Gina
- Agesa Kareha M
- Aggarwal Rakesh
- Aghayan Sargis Aghasi
- Agrawal Sutapa
- Ahmadi Alireza
- Ahmadi Mehdi
- Ahmadieh Hamid
- Ahmed Muktar Beshir
- Aichour Amani Nidhal
- Aichour Ibtihel
- Aichour Miloud Taki Eddine
- Akinyemiju Tomi
- Akseer Nadia
- Al-Aly Ziyad
- Al-Eyadhy Ayman
- Al-Mekhlafi Hesham M
- Al-Raddadi Rajaa M
- Alahdab Fares
- Alam Khurshid
- Alam Tahiya
- Alashi Alaa
- Alavian Seyed Moayed
- Alene Kefyalew Addis
- Alijanzadeh Mehran
- Alizadeh-Navaei Reza
- Aljunid Syed Mohamed
- Alkerwi Ala'a
- Alla François
- Allebeck Peter
- Alouani Mohamed M L
- Altirkawi Khalid
- Alvis-Guzman Nelson
- Amare Azmeraw T
- Aminde Leopold N
- Ammar Walid
- Amoako Yaw Ampem
- Anber Nahla Hamed
- Andrei Catalina Liliana
- Androudi Sofia
- Animut Megbaru Debalkie
- Anjomshoa Mina
- Ansha Mustafa Geleto
- Antonio Carl Abelardo T
- Anwari Palwasha
- Arabloo Jalal
- Arauz Antonio
- Aremu Olatunde
- Ariani Filippo
- Armoon Bahroom
- Arora Amit
- Artaman Al
- Aryal Krishna K
- Asayesh Hamid
- Asghar Rana Jawad
- Ataro Zerihun
- Atre Sachin R
- Ausloos Marcel
- Avila-Burgos Leticia
- Avokpaho Euripide F G A
- Awasthi Ashish
- Ayala Quintanilla Beatriz Paulina
- Ayer Rakesh
- Azzopardi Peter S
- Babazadeh Arefeh
- Badali Hamid
- Badawi Alaa
- Bali Ayele Geleto
- Ballesteros Katherine E
- Ballew Shoshana H
- Banach Maciej
- Banoub Joseph Adel Mattar
- Banstola Amrit
- Barac Aleksandra
- Barboza Miguel A
- Barker-Collo Suzanne Lyn
- Barrero Lope H
- Baune Bernhard T
- Bazargan-Hejazi Shahrzad
- Bedi Neeraj
- Beghi Ettore
- Behzadifar Masoud
- Behzadifar Meysam
- Belachew Abate Bekele
- Belay Yihalem Abebe
- Bell Michelle L
- Bello Aminu K
- Bensenor Isabela M
- Bernabe Eduardo
- Bernstein Robert S
- Beuran Mircea
- Beyranvand Tina
- Bhala Neeraj
- Bhattarai Suraj
- Bhaumik Soumyadeep
- Bhutta Zulfiqar A
- Biadgo Belete
- Bijani Ali
- Bikbov Boris
- Bilano Ver
- Bililign Nigus
- Bin Sayeed Muhammad Shahdaat
- Bisanzio Donal
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- Britton Gabrielle
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- Bärnighausen Till Winfried
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- Chaturvedi Pankaj
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- Cooper Cyrus
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- Cross Marita
- Crump John A
- Cárdenas Rosario
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- Das Gupta Rajat
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- Demoz Gebre Teklemariam
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- Dirac M Ashworth
- Djalalinia Shirin
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- Dokova Klara
- Doku David Teye
- Dorsey E Ray
- Doyle Kerrie E
- Driscoll Tim Robert
- Dubey Manisha
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- Edvardsson David
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- El Bcheraoui Charbel
- El Sayed Zaki Maysaa
- El-Khatib Ziad
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- Elyazar Iqbal R F
- Enayati Ahmadali
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- Er Benjamin
- Erskine Holly E
- Eshrati Babak
- Eskandarieh Sharareh
- Esteghamati Alireza
- Esteghamati Sadaf
- Fakhim Hamed
- Fallah Omrani Vahid
- Faramarzi Mahbobeh
- Fareed Mohammad
- Farhadi Farzaneh
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- Farinha Carla Sofia E sá
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- Farvid Maryam S
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- Ghasemi-Kasman Maryam
- Ghimire Mamata
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- Haagsma Juanita A
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- Herteliu Claudiu
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- Hoang Huong Thanh
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- Htet Aung Soe
- Hu Guoqing
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- Huynh Chantal K
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- Ikeda Chad Thomas
- Ileanu Bogdan
- Ilesanmi Olayinka Stephen
- Iqbal Usman
- Irvani Seyed Sina Naghibi
- Irvine Caleb Mackay Salpeter
- Islam Sheikh Mohammed Shariful
- Islami Farhad
- Jacobsen Kathryn H
- Jahangiry Leila
- Jahanmehr Nader
- Jain Sudhir Kumar
- Jakovljevic Mihajlo
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- Jeemon Panniyammakal
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- Jonas Jost B
- Jozwiak Jacek Jerzy
- Jungari Suresh Banayya
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- Keren Andre
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- Khafaie Morteza Abdullatif
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- Khan Ejaz Ahmad
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- Khosravi Ardeshir
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- Misganaw Awoke Temesgen
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- Mitiku Habtamu
- Moazen Babak
- Mohajer Bahram
- Mohammad Karzan Abdulmuhsin
- Mohammadifard Noushin
- Mohammadnia-Afrouzi Mousa
- Mohammed Mohammed A
- Mohammed Shafiu
- Mohebi Farnam
- Moitra Modhurima
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- Morrison Shane Douglas
- Moschos Marilita M
- Mousavi Seyyed Meysam
- Mruts Kalayu Brhane
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- Muchie Kindie Fentahun
- Mueller Ulrich Otto
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- Muller Kate
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- Musa Jonah
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- Nagata Chie
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- Nahvijou Azin
- Naik Gurudatta
- Naik Nitish
- Najafi Farid
- Naldi Luigi
- Nam Hae Sung
- Nangia Vinay
- Nansseu Jobert Richie
- Nascimento Bruno Ramos
- Natarajan Gopalakrishnan
- Neamati Nahid
- Negoi Ionut
- Negoi Ruxandra Irina
- Neupane Subas
- Newton Charles Richard James
- Ngunjiri Josephine W
- Nguyen Anh Quynh
- Nguyen Ha Thu
- Nguyen Huong Lan Thi
- Nguyen Huong Thanh
- Nguyen Long Hoang
- Nguyen Minh
- Nguyen Nam Ba
- Nguyen Son Hoang
- Nichols Emma
- Ningrum Dina Nur Anggraini
- Nixon Molly R
- Nolutshungu Nomonde
- Nomura Shuhei
- Norheim Ole F
- Noroozi Mehdi
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- Olsen Helen Elizabeth
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- Otstavnov Stanislav S
- Owolabi Mayowa Ojo
- P A Mahesh
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- Plass Dietrich
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- Radfar Amir
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- Rafiei Alireza
- Rahim Fakher
- Rahimi Kazem
- Rahimi-Movaghar Afarin
- Rahimi-Movaghar Vafa
- Rahman Mahfuzar
- Rahman Mohammad Hifz ur
- Rahman Muhammad Aziz
- Rahman Sajjad Ur
- Rai Rajesh Kumar
- Rajati Fatemeh
- Ram Usha
- Ranjan Prabhat
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- Resnikoff Serge
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- Roever Leonardo
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- Roshandel Gholamreza
- Rostami Ali
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- Roy Ambuj
- Rubagotti Enrico
- Sachdev Perminder S
- Sadat Nafis
- Saddik Basema
- Sadeghi Ehsan
- Saeedi Moghaddam Sahar
- Safari Hosein
- Safari Yahya
- Safari-Faramani Roya
- Safdarian Mahdi
- Safi Sare
- Safiri Saeid
- Sagar Rajesh
- Sahebkar Amirhossein
- Sahraian Mohammad Ali
- Sajadi Haniye Sadat
- Salam Nasir
- Salama Joseph S
- Salamati Payman
- Saleem Komal
- Saleem Zikria
- Salimi Yahya
- Salomon Joshua A
- Salvi Sundeep Santosh
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- Sang Yingying
- Santomauro Damian Francesco
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- Santos João Vasco
- Santric Milicevic Milena M
- Sao Jose Bruno Piassi
- Sardana Mayank
- Sarker Abdur Razzaque
- Sarrafzadegan Nizal
- Sartorius Benn
- Sarvi Shahabeddin
- Sathian Brijesh
- Satpathy Maheswar
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- Sawhney Monika
- Saxena Sonia
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- Schöttker Ben
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- Sekerija Mario
- Sepanlou Sadaf G
- Serván-Mori Edson
- Seyedmousavi Seyedmojtaba
- Shabaninejad Hosein
- Shafieesabet Azadeh
- Shahbazi Mehdi
- Shaheen Amira A
- Shaikh Masood Ali
- Shams-Beyranvand Mehran
- Shamsi Mohammadbagher
- Shamsizadeh Morteza
- Sharafi Heidar
- Sharafi Kiomars
- Sharif Mehdi
- Sharif-Alhoseini Mahdi
- Sharma Meenakshi
- Sharma Rajesh
- She Jun
- Sheikh Aziz
- Shi Peilin
- Shibuya Kenji
- Shigematsu Mika
- Shiri Rahman
- Shirkoohi Reza
- Shishani Kawkab
- Shiue Ivy
- Shokraneh Farhad
- Shoman Haitham
- Shrime Mark G
- Si Si
- Siabani Soraya
- Siddiqi Tariq J
- Sigfusdottir Inga Dora
- Sigurvinsdottir Rannveig
- Silva João Pedro
- Silveira Dayane Gabriele Alves
- Singam Narayana Sarma Venkata
- Singh Jasvinder A
- Singh Narinder Pal
- Singh Virendra
- Sinha Dhirendra Narain
- Skiadaresi Eirini
- Slepak Erica Leigh N
- Sliwa Karen
- Smith David L
- Smith Mari
- Soares Filho Adauto Martins
- Sobaih Badr Hasan
- Sobhani Soheila
- Sobngwi Eugène
- Soneji Samir S
- Soofi Moslem
- Soosaraei Masoud
- Sorensen Reed J D
- Soriano Joan B
- Soyiri Ireneous N
- Sposato Luciano A
- Sreeramareddy Chandrashekhar T
- Srinivasan Vinay
- Stanaway Jeffrey D
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- Steiner Caitlyn
- Steiner Timothy J
- Stokes Mark A
- Stovner Lars Jacob
- Subart Michelle L
- Sudaryanto Agus
- Sufiyan Mu'awiyyah Babale
- Sunguya Bruno F
- Sur Patrick John
- Sutradhar Ipsita
- Sykes Bryan L
- Sylte Dillon O
- Tabarés-Seisdedos Rafael
- Tadakamadla Santosh Kumar
- Tadesse Birkneh Tilahun
- Tandon Nikhil
- Tassew Segen Gebremeskel
- Tavakkoli Mohammad
- Taveira Nuno
- Taylor Hugh R
- Tehrani-Banihashemi Arash
- Tekalign Tigist Gashaw
- Tekelemedhin Shishay Wahdey
- Tekle Merhawi Gebremedhin
- Temesgen Habtamu
- Temsah Mohamad-Hani
- Temsah Omar
- Terkawi Abdullah Sulieman
- Teweldemedhin Mebrahtu
- Thankappan Kavumpurathu Raman
- Thomas Nihal
- Tilahun Binyam
- To Quyen G
- Tonelli Marcello
- Topor-Madry Roman
- Topouzis Fotis
- Torre Anna E
- Tortajada-Girbés Miguel
- Touvier Mathilde
- Tovani-Palone Marcos Roberto
- Towbin Jeffrey A
- Tran Bach Xuan
- Tran Khanh Bao
- Troeger Christopher E
- Truelsen Thomas Clement
- Tsilimbaris Miltiadis K
- Tsoi Derrick
- Tudor Car Lorainne
- Tuzcu E Murat
- Ukwaja Kingsley N
- Ullah Irfan
- Undurraga Eduardo A
- Unutzer Jurgen
- Updike Rachel L
- Usman Muhammad Shariq
- Uthman Olalekan A
- Vaduganathan Muthiah
- Vaezi Afsane
- Valdez Pascual R
- Varughese Santosh
- Vasankari Tommi Juhani
- Venketasubramanian Narayanaswamy
- Villafaina Santos
- Violante Francesco S
- Vladimirov Sergey Konstantinovitch
- Vlassov Vasily
- Vollset Stein Emil
- Vos Theo
- Vosoughi Kia
- Vujcic Isidora S
- Wagnew Fasil Shiferaw
- Waheed Yasir
- Waller Stephen G
- Wang Yafeng
- Wang Yuan-Pang
- Weiderpass Elisabete
- Weintraub Robert G
- Weiss Daniel J
- Weldegebreal Fitsum
- Weldegwergs Kidu Gidey
- Werdecker Andrea
- West T Eoin
- Whiteford Harvey A
- Widecka Justyna
- Wijeratne Tissa
- Wilner Lauren B
- Wilson Shadrach
- Winkler Andrea Sylvia
- Wiyeh Alison B
- Wiysonge Charles Shey
- Wolfe Charles D A
- Woolf Anthony D
- Wu Shouling
- Wu Yun-Chun
- Wyper Grant M A
- Xavier Denis
- Xu Gelin
- Yadgir Simon
- Yadollahpour Ali
- Yahyazadeh Jabbari Seyed Hossein
- Yamada Tomohide
- Yan Lijing L
- Yano Yuichiro
- Yaseri Mehdi
- Yasin Yasin Jemal
- Yeshaneh Alex
- Yimer Ebrahim M
- Yip Paul
- Yisma Engida
- Yonemoto Naohiro
- Yoon Seok-Jun
- Yotebieng Marcel
- Younis Mustafa Z
- Yousefifard Mahmoud
- Yu Chuanhua
- Zadnik Vesna
- Zaidi Zoubida
- Zaman Sojib Bin
- Zamani Mohammad
- Zare Zohreh
- Zeleke Ayalew Jejaw
- Zenebe Zerihun Menlkalew
- Zhang Kai
- Zhao Zheng
- Zhou Maigeng
- Zodpey Sanjay
- Zucker Inbar
- Ärnlöv Johan
- Øverland Simon
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2018
- Field of study
The Global Burden of Diseases, Injuries and Risk Factors 2017 includes a comprehensive assessment of incidence, prevalence, and years lived with disability (YLDs) for 354 causes in 195 countries and territories from 1990 to 2017. Previous GBD studies have shown how the decline of mortality rates from 1990 to 2016 has led to an increase in life expectancy, an ageing global population, and an expansion of the non-fatal burden of disease and injury. These studies have also shown how a substantial portion of the world's population experiences non-fatal health loss with considerable heterogeneity among different causes, locations, ages, and sexes. Ongoing objectives of the GBD study include increasing the level of estimation detail, improving analytical strategies, and increasing the amount of high-quality data. METHODS: We estimated incidence and prevalence for 354 diseases and injuries and 3484 sequelae. We used an updated and extensive body of literature studies, survey data, surveillance data, inpatient admission records, outpatient visit records, and health insurance claims, and additionally used results from cause of death models to inform estimates using a total of 68 781 data sources. Newly available clinical data from India, Iran, Japan, Jordan, Nepal, China, Brazil, Norway, and Italy were incorporated, as well as updated claims data from the USA and new claims data from Taiwan (province of China) and Singapore. We used DisMod-MR 2.1, a Bayesian meta-regression tool, as the main method of estimation, ensuring consistency between rates of incidence, prevalence, remission, and cause of death for each condition. YLDs were estimated as the product of a prevalence estimate and a disability weight for health states of each mutually exclusive sequela, adjusted for comorbidity. We updated the Socio-demographic Index (SDI), a summary development indicator of income per capita, years of schooling, and total fertility rate. Additionally, we calculated differences between male and female YLDs to identify divergent trends across sexes. GBD 2017 complies with the Guidelines for Accurate and Transparent Health Estimates Reporting
Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.
- Author
- Abate Degu
- Abate Kalkidan Hassen
- Abay Solomon M
- Abbafati Cristiana
- Abbasi Nooshin
- Abbastabar Hedayat
- Abd-Allah Foad
- Abdela Jemal
- Abdelalim Ahmed
- Abdollahpour Ibrahim
- Abdulkader Rizwan Suliankatchi
- Abebe Molla
- Abebe Zegeye
- Abil Olifan Zewdie
- Aboyans Victor
- Abrham Aklilu Roba
- Abu-Raddad Laith Jamal
- Abu-Rmeileh Niveen M E
- Accrombessi Manfred Mario Kokou
- Acharya Dilaram
- Acharya Pawan
- Ackerman Ilana N
- Adamu Abdu A
- Adebayo Oladimeji M
- Adekanmbi Victor
- Ademi Zanfina
- Adetokunboh Olatunji O
- Adib Mina G
- Adsuar Jose C
- Afanvi Kossivi Agbelenko
- Afarideh Mohsen
- Afshin Ashkan
- Agarwal Gina
- Agesa Kareha M
- Aggarwal Rakesh
- Aghayan Sargis Aghasi
- Agrawal Anurag
- Ahmadi Alireza
- Ahmadi Mehdi
- Ahmadieh Hamid
- Ahmed Muktar Beshir
- Ahmed Sayem
- Aichour Amani Nidhal
- Aichour Ibtihel
- Aichour Miloud Taki Eddine
- Akinyemiju Tomi
- Akseer Nadia
- Al-Aly Ziyad
- Al-Eyadhy Ayman
- Al-Mekhlafi Hesham M
- Al-Raddadi Rajaa M
- Alahdab Fares
- Alam Khurshid
- Alam Tahiya
- Alashi Alaa
- Alavian Seyed Moayed
- Alene Kefyalew Addis
- Alijanzadeh Mehran
- Alizadeh-Navaei Reza
- Aljunid Syed Mohamed
- Alkerwi Ala'a
- Alla François
- Allebeck Peter
- Alonso Jordi
- Alsharif Ubai
- Altirkawi Khalid
- Alvis-Guzman Nelson
- Aminde Leopold N
- Amini Erfan
- Amiresmaili Mohammadreza
- Ammar Walid
- Amoako Yaw Ampem
- Anber Nahla Hamed
- Andrei Catalina Liliana
- Androudi Sofia
- Animut Megbaru Debalkie
- Anjomshoa Mina
- Ansha Mustafa Geleto
- Antonio Carl Abelardo T
- Anwari Palwasha
- Arabloo Jalal
- Aremu Olatunde
- Arora Amit
- Arora Megha
- Artaman Al
- Aryal Krishna K
- Asayesh Hamid
- Ataro Zerihun
- Ausloos Marcel
- Avila-Burgos Leticia
- Avokpaho Euripide F G A
- Awasthi Ashish
- Ayala Quintanilla Beatriz Paulina
- Ayer Rakesh
- Azzopardi Peter S
- Babazadeh Arefeh
- Badali Hamid
- Balakrishnan Kalpana
- Bali Ayele Geleto
- Banach Maciej
- Banoub Joseph Adel Mattar
- Barac Aleksandra
- Barboza Miguel A
- Barker-Collo Suzanne Lyn
- Barquera Simon
- Barrero Lope H
- Bazargan-Hejazi Shahrzad
- Bedi Neeraj
- Beghi Ettore
- Behzadifar Masoud
- Behzadifar Meysam
- Bekele Bayu Begashaw
- Bekru Eyasu Tamru
- Belachew Abate Bekele
- Belay Yihalem Abebe
- Bell Michelle L
- Bello Aminu K
- Bennett Derrick A
- Bensenor Isabela M
- Berhane Adugnaw
- Bernabe Eduardo
- Bernstein Robert S
- Beuran Mircea
- Beyranvand Tina
- Bhala Neeraj
- Bhatt Samir
- Bhaumik Soumyadeep
- Bhutta Zulfiqar A
- Biadgo Belete
- Biehl Molly H
- Bijani Ali
- Bikbov Boris
- Bilano Ver
- Bililign Nigus
- Bin Sayeed Muhammad Shahdaat
- Bisanzio Donal
- Bjørge Tone
- Bleyer Archie
- Bobasa Eshetu Mulisa
- Bou-Orm Ibrahim R
- Boufous Soufiane
- Bourne Rupert
- Brady Oliver J
- Brant Luisa C
- Brayne Carol
- Brazinova Alexandra
- Breitborde Nicholas J K
- Brenner Hermann
- Briant Paul Svitil
- Briko Andrey Nikolaevich
- Britton Gabrielle
- Brugha Traolach
- Buchbinder Rachelle
- Busse Reinhard
- Butt Zahid A
- Bärnighausen Till Winfried
- Cahuana-Hurtado Lucero
- Campuzano Rincon Julio Cesar
- Cano Jorge
- Carrero Juan J
- Carter Austin
- Carvalho Félix
- Castañeda-Orjuela Carlos A
- Castillo Rivas Jacqueline
- Castro Franz
- Catalá-López Ferrán
- Cercy Kelly M
- Cerin Ester
- Chaiah Yazan
- Chang Jung-Chen
- Charlson Fiona J
- Chattu Vijay Kumar
- Chiang Peggy Pei-Chia
- Chitheer Abdulaal
- Choi Jee-Young J
- Christensen Hanne
- Christopher Devasahayam J
- Chung Sheng-Chia
- Cicuttini Flavia M
- Cirillo Massimo
- Collado-Mateo Daniel
- Cooper Cyrus
- Cortesi Paolo Angelo
- Cortinovis Monica
- Cousin Ewerton
- Criqui Michael H
- Cromwell Elizabeth A
- Cross Marita
- Crump John A
- Cárdenas Rosario
- Daba Alemneh Kabeta
- Dachew Berihun Assefa
- Dadi Abel Fekadu
- Dandona Lalit
- Dandona Rakhi
- Dargan Paul I
- Daryani Ahmad
- Das Gupta Rajat
- Das Neves José
- Dasa Tamirat Tesfaye
- Davitoiu Dragos Virgil
- De La Hoz Fernando Pio
- De Leo Diego
- De Neve Jan-Walter
- De Steur Hans
- Degefa Meaza Girma
- Degenhardt Louisa
- Deiparine Selina
- Demoz Gebre Teklemariam
- Denova-Gutiérrez Edgar
- Deribe Kebede
- Dervenis Nikolaos
- Des Jarlais Don C
- Dey Subhojit
- Dharmaratne Samath D
- Dhimal Meghnath
- Dinberu Mesfin Tadese
- Dirac M Ashworth
- Djalalinia Shirin
- Doan Linh
- Dokova Klara
- Doku David Teye
- Dorsey E Ray
- Doyle Kerrie E
- Driscoll Tim Robert
- Dubey Manisha
- Dubljanin Eleonora
- Duken Eyasu Ejeta
- Duncan Bruce B
- Duraes Andre R
- Ebrahimi Hedyeh
- Ebrahimpour Soheil
- Echko Michelle M
- Edessa Dumessa
- Edvardsson David
- Effiong Andem
- Eggen Anne Elise
- Ehrlich Joshua R
- El Bcheraoui Charbel
- El-Khatib Ziad
- Elyazar Iqbal R F
- Enayati Ahmadali
- Endalifer Melese Linger
- Endries Aman Yesuf
- Er Benjamin
- Erskine Holly E
- Eskandarieh Sharareh
- Esteghamati Alireza
- Esteghamati Sadaf
- Fakhim Hamed
- Faramarzi Mahbobeh
- Fareed Mohammad
- Farhadi Farzaneh
- Farid Talha A
- Farinha Carla Sofia E sá
- Farioli Andrea
- Faro Andre
- Farzadfar Farshad
- Fazaeli Ali Akbar
- Feigin Valery L
- Fentahun Netsanet
- Fereshtehnejad Seyed-Mohammad
- Fernandes Eduarda
- Fernandes Joao C
- Ferrari Alize J
- Ferreira Manuela L
- Filip Irina
- Fischer Florian
- Fitzmaurice Christina
- Foigt Nataliya A
- Foreman Kyle J
- Frank Tahvi D
- Fukumoto Takeshi
- Fullman Nancy
- Furtado João M
- Fürst Thomas
- Gakidou Emmanuela
- Gall Seana
- Gallus Silvano
- Ganji Morsaleh
- Garcia-Basteiro Alberto L
- Gardner William M
- Gebre Abadi Kahsu
- Gebremedhin Amanuel Tesfay
- Gebremichael Teklu Gebrehiwo
- Gelano Tilayie Feto
- Geleijnse Johanna M
- Genova-Maleras Ricard
- Geramo Yilma Chisha Dea
- Gething Peter W
- Gezae Kebede Embaye
- Ghadami Mohammad Rasoul
- Ghadiri Keyghobad
- Ghasemi-Kasman Maryam
- Ghimire Mamata
- Ghoshal Aloke Gopal
- Gill Paramjit Singh
- Gill Tiffany K
- Ginawi Ibrahim Abdelmageed
- Giussani Giorgia
- Gnedovskaya Elena V
- Goldberg Ellen M
- Goli Srinivas
- Gona Philimon N
- Gopalani Sameer Vali
- Gorman Taren M
- Goulart Alessandra C
- Goulart Bárbara Niegia Garcia
- Grada Ayman
- Grosso Giuseppe
- Gugnani Harish Chander
- Guillemin Francis
- Guo Yuming
- Gupta Prakash C
- Gupta Rahul
- Gupta Rajeev
- Gupta Tanush
- Gutiérrez Reyna Alma
- Gyawali Bishal
- Gómez-Dantés Hector
- Haagsma Juanita A
- Hachinski Vladimir
- Hafezi-Nejad Nima
- Haghparast Bidgoli Hassan
- Hagos Tekleberhan B
- Hailegiyorgis Tewodros Tesfa
- Haj-Mirzaian Arvin
- Haj-Mirzaian Arya
- Hamadeh Randah R
- Hamidi Samer
- Handal Alexis J
- Hankey Graeme J
- Hao Yuantao
- Harb Hilda L
- Harikrishnan Sivadasanpillai
- Haririan Hamidreza
- Haro Josep Maria
- Hassankhani Hadi
- Hassen Hamid Yimam
- Havmoeller Rasmus
- Hay Roderick J
- Hay Simon I
- Hedayatizadeh-Omran Akbar
- Heibati Behzad
- Hendrie Delia
- Henok Andualem
- Heredia-Pi Ileana
- Herteliu Claudiu
- Heydarpour Fatemeh
- Heydarpour Pouria
- Hibstu Desalegn Tsegaw
- Hoek Hans W
- Hoffman Howard J
- Hole Michael K
- Homaie Rad Enayatollah
- Hoogar Praveen
- Hosgood H Dean
- Hosseini Seyed Mostafa
- Hosseinzadeh Mehdi
- Hostiuc Mihaela
- Hostiuc Sorin
- Hotez Peter J
- Hoy Damian G
- Hsairi Mohamed
- Htet Aung Soe
- Huang John J
- Iburg Kim Moesgaard
- Ikeda Chad Thomas
- Ilesanmi Olayinka Stephen
- Irvani Seyed Sina Naghibi
- Irvine Caleb Mackay Salpeter
- Islam Sheikh Mohammed Shariful
- Islami Farhad
- Jacobsen Kathryn H
- Jahangiry Leila
- Jahanmehr Nader
- Jain Sudhir Kumar
- Jakovljevic Mihajlo
- James Spencer L
- Jayatilleke Achala Upendra
- Jeemon Panniyammakal
- Jha Ravi Prakash
- Jha Vivekanand
- Ji John S
- Johnson Catherine O
- Jonas Jost B
- Jonnagaddala Jitendra
- Jorjoran Shushtari Zahra
- Joshi Ankur
- Jozwiak Jacek Jerzy
- Jungari Suresh Banayya
- Jürisson Mikk
- Kabir Zubair
- Kadel Rajendra
- Kahsay Amaha
- Kalani Rizwan
- Kanchan Tanuj
- Kar Chittaranjan
- Karami Matin Behzad
- Karami Manoochehr
- Karch André
- Karema Corine
- Karimi Narges
- Karimi Seyed M
- Karyani Ali Kazemi
- Kasaeian Amir
- Kassa Dessalegn H
- Kassa Getachew Mullu
- Kassa Tesfaye Dessale
- Kassebaum Nicholas J
- Katikireddi Srinivasa Vittal
- Kaul Anil
- Kawakami Norito
- Kazemi Zhila
- Keighobadi Masoud Masoud
- Keiyoro Peter Njenga
- Kemmer Laura
- Kemp Grant Rodgers
- Kengne Andre Pascal
- Keren Andre
- Khader Yousef Saleh
- Khafaei Behzad
- Khafaie Morteza Abdullatif
- Khajavi Alireza
- Khalid Nauman
- Khalil Ibrahim A
- Khan Ejaz Ahmad
- Khan Muhammad Ali
- Khan Muhammad Shahzeb
- Khang Young-Ho
- Khater Mona M
- Khazaei Mohammad
- Khoja Abdullah T
- Khosravi Ardeshir
- Khosravi Mohammad Hossein
- Kiadaliri Aliasghar A
- Kidanemariam Zelalem Teklemariam
- Kiirithio Daniel N
- Kim Cho-Il
- Kim Daniel
- Kim Young-Eun
- Kim Yun Jin
- Kimokoti Ruth W
- Kinfu Yohannes
- Kisa Adnan
- Kissimova-Skarbek Katarzyna
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- Nangia Vinay
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- Negoi Ionut
- Negoi Ruxandra Irina
- Neupane Subas
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- Nguyen Anh Quynh
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- Nguyen Ha Thu
- Nguyen Huong Lan Thi
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- Rafiei Alireza
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- Rahimi-Movaghar Afarin
- Rahimi-Movaghar Vafa
- Rahman Mahfuzar
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- Ranjan Prabhat
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- Rothenbacher Dietrich
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- Sadat Nafis
- Sadeghi Ehsan
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- Safdarian Mahdi
- Safi Sare
- Safiri Saeid
- Sagar Rajesh
- Sahebkar Amirhossein
- Sahraian Mohammad Ali
- Sajadi Haniye Sadat
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- Salamati Payman
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- Salvi Sundeep Santosh
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- Sarker Abdur Razzaque
- Sarmiento-Suárez Rodrigo
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- Seyedmousavi Seyedmojtaba
- Shabaninejad Hosein
- Shafieesabet Azadeh
- Shahbazi Mehdi
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- Shaikh Masood Ali
- Shams-Beyranvand Mehran
- Shamsi Mohammadbagher
- Sharafi Heidar
- Sharafi Kiomars
- Sharif Mehdi
- Sharif-Alhoseini Mahdi
- Sharma Jayendra
- Sharma Rajesh
- She Jun
- Sheikh Aziz
- Shi Peilin
- Shiadeh Malihe Nourollahpour
- Shibuya Kenji
- Shiferaw Mekonnen Sisay
- Shigematsu Mika
- Shiri Rahman
- Shirkoohi Reza
- Shiue Ivy
- Shokoohinia Yalda
- Shokraneh Farhad
- Shoman Haitham
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- Siabani Soraya
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- Sigfusdottir Inga Dora
- Sigurvinsdottir Rannveig
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- Tavakkoli Mohammad
- Taveira Nuno
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- Tehrani-Banihashemi Arash
- Tekalign Tigist Gashaw
- Tekelemedhin Shishay Wahdey
- Tekle Merhawi Gebremedhin
- Temsah Mohamad-Hani
- Temsah Omar
- Terkawi Abdullah Sulieman
- Tessema Belay
- Teweldemedhin Mebrahtu
- Thankappan Kavumpurathu Raman
- Theis Andrew
- Thirunavukkarasu Sathish
- Thomas Nihal
- Tilahun Binyam
- To Quyen G
- Tonelli Marcello
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- Torre Anna E
- Tortajada-Girbés Miguel
- Touvier Mathilde
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- Towbin Jeffrey A
- Tran Bach Xuan
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- Troeger Christopher E
- Tsadik Afewerki Gebremeskel
- Tsoi Derrick
- Tudor Car Lorainne
- Tyrovolas Stefanos
- Ukwaja Kingsley Nnanna
- Ullah Irfan
- Undurraga Eduardo A
- Updike Rachel L
- Usman Muhammad Shariq
- Uthman Olalekan A
- Vaduganathan Muthiah
- Vaezi Afsane
- Valdez Pascual R
- Varavikova Elena
- Varughese Santosh
- Vasankari Tommi Juhani
- Venketasubramanian Narayanaswamy
- Villafaina Santos
- Violante Francesco S
- Vladimirov Sergey Konstantinovitch
- Vlassov Vasily
- Vollset Stein Emil
- Vos Theo
- Vosoughi Kia
- Vujcic Isidora S
- Wagnew Fasil Shiferaw
- Waheed Yasir
- Wang Yafeng
- Wang Yuan-Pang
- Weiderpass Elisabete
- Weintraub Robert G
- Weiss Daniel J
- Weldegebreal Fitsum
- Weldegwergs Kidu Gidey
- Werdecker Andrea
- West T Eoin
- Westerman Ronny
- Whiteford Harvey A
- Widecka Justyna
- Wijeratne Tissa
- Williams Hywel C
- Wilner Lauren B
- Wilson Shadrach
- Winkler Andrea Sylvia
- Wiyeh Alison B
- Wiysonge Charles Shey
- Wolfe Charles D A
- Woolf Anthony D
- Wyper Grant M A
- Xavier Denis
- Xu Gelin
- Yadgir Simon
- Yahyazadeh Jabbari Seyed Hossein
- Yamada Tomohide
- Yan Lijing L
- Yano Yuichiro
- Yaseri Mehdi
- Yasin Yasin Jemal
- Yeshaneh Alex
- Yimer Ebrahim M
- Yip Paul
- Yisma Engida
- Yonemoto Naohiro
- Yoon Seok-Jun
- Yotebieng Marcel
- Younis Mustafa Z
- Yousefifard Mahmoud
- Yu Chuanhua
- Zadnik Vesna
- Zaidi Zoubida
- Zaman Sojib Bin
- Zamani Mohammad
- Zandian Hamed
- Zar Heather J
- Zenebe Zerihun Menlkalew
- Zhou Maigeng
- Zipkin Ben
- Zodpey Sanjay
- Zucker Inbar
- Zuhlke Liesl Joanna
- Ärnlöv Johan
- Øverland Simon
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2018
- Field of study
How long one lives, how many years of life are spent in good and poor health, and how the population's state of health and leading causes of disability change over time all have implications for policy, planning, and provision of services. We comparatively assessed the patterns and trends of healthy life expectancy (HALE), which quantifies the number of years of life expected to be lived in good health, and the complementary measure of disability-adjusted life-years (DALYs), a composite measure of disease burden capturing both premature mortality and prevalence and severity of ill health, for 359 diseases and injuries for 195 countries and territories over the past 28 years. Methods We used data for age-specific mortality rates, years of life lost (YLLs) due to premature mortality, and years lived with disability (YLDs) from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 to calculate HALE and DALYs from 1990 to 2017. We calculated HALE using age-specific mortality rates and YLDs per capita for each location, age, sex, and year. We calculated DALYs for 359 causes as the sum of YLLs and YLDs. We assessed how observed HALE and DALYs differed by country and sex from expected trends based on Socio-demographic Index (SDI). We also analysed HALE by decomposing years of life gained into years spent in good health and in poor health, between 1990 and 2017, and extra years lived by females compared with males. Findings Globally, from 1990 to 2017, life expectancy at birth increased by 7·4 years (95% uncertainty interval 7·1-7·8), from 65·6 years (65·3-65·8) in 1990 to 73·0 years (72·7-73·3) in 2017. The increase in years of life varied from 5·1 years (5·0-5·3) in high SDI countries to 12·0 years (11·3-12·8) in low SDI countries. Of the additional years of life expected at birth, 26·3% (20·1-33·1) were expected to be spent in poor health in high SDI countries compared with 11·7% (8·8-15·1) in low-middle SDI countries. HALE at birth increased by 6·3 years (5·9-6·7), from 57·0 years (54·6-59·1) in 1990 to 63·3 years (60·5-65·7) in 2017. The increase varied from 3·8 years (3·4-4·1) in high SDI countries to 10·5 years (9·8-11·2) in low SDI countries. Even larger variations in HALE than these were observed between countries, ranging from 1·0 year (0·4-1·7) in Saint Vincent and the Grenadines (62·4 years [59·9-64·7] in 1990 to 63·5 years [60·9-65·8] in 2017) to 23·7 years (21·9-25·6) in Eritrea (30·7 years [28·9-32·2] in 1990 to 54·4 years [51·5-57·1] in 2017). In most countries, the increase in HALE was smaller than the increase in overall life expectancy, indicating more years lived in poor health. In 180 of 195 countries and territories, females were expected to live longer than males in 2017, with extra years lived varying from 1·4 years (0·6-2·3) in Algeria to 11·9 years (10·9-12·9) in Ukraine. Of the extra years gained, the proportion spent in poor health varied largely across countries, with less than 20% of additional years spent in poor health in Bosnia and Herzegovina, Burundi, and Slovakia, whereas in Bahrain all the extra years were spent in poor health. In 2017, the highest estimate of HALE at birth was in Singapore for both females (75·8 years [72·4-78·7]) and males (72·6 years [69·8-75·0]) and the lowest estimates were in Central African Republic (47·0 years [43·7-50·2] for females and 42·8 years [40·1-45·6] for males). Globally, in 2017, the five leading causes of DALYs were neonatal disorders, ischaemic heart disease, stroke, lower respiratory infections, and chronic obstructive pulmonary disease. Between 1990 and 2017, age-standardised DALY rates decreased by 41·3% (38·8-43·5) for communicable diseases and by 49·8% (47·9-51·6) for neonatal disorders. For non-communicable diseases, global DALYs increased by 40·1% (36·8-43·0), although age-standardised DALY rates decreased by 18·1% (16·0-20·2)
Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017
- Author
- Abate Degu
- Abay Solomon M
- Abbafati Cristiana
- Abbasi Nooshin
- Abbastabar Hedayat
- Abd-Allah Foad
- Abdel-Rahman Omar
- Abdela Jemal
- Abdelalim Ahmed
- Abdi Alireza
- Abdollahpour Ibrahim
- Abdulkader Rizwan Suliankatchi
- Abebe Nebiyu Dereje
- Abebe Zegeye
- Abejie Ayenew Negesse
- Abera Semaw F
- Abil Olifan Zewdie
- Aboyans Victor
- Abraha Haftom Niguse
- Abrham Aklilu Roba
- Abu-Raddad Laith Jamal
- Abu-Rmeileh Niveen Me
- Abyu Gebre Y
- Accrombessi Manfred Mario Kokou
- Acharya Dilaram
- Acharya Pawan
- Adamu Abdu A
- Adebayo Oladimeji M
- Adedeji Isaac Akinkunmi
- Adedoyin Rufus Adesoji
- Adekanmbi Victor
- Adetokunboh Olatunji O
- Adhena Beyene Meressa
- Adhikari Tara Ballav
- Adib Mina G
- Adou Arsène Kouablan
- Adsuar Jose C
- Afarideh Mohsen
- Afshari Mahdi
- Afshin Ashkan
- Agarwal Gina
- Aghayan Sargis Aghasi
- Agius Dominic
- Agrawal Anurag
- Agrawal Sutapa
- Ahmadi Alireza
- Ahmadi Mehdi
- Ahmadieh Hamid
- Ahmed Muktar Beshir
- Ahmed Sayem
- Akalu Temesgen Yihunie
- Akanda Ali S
- Akbari Mohammad Esmaeil
- Akibu Mohammed
- Akinyemi Rufus Olusola
- Akinyemiju Tomi
- Akseer Nadia
- Al-Aly Ziyad
- Al-Eyadhy Ayman
- Al-Maskari Fatma
- Al-Mekhlafi Hesham M
- Al-Raddadi Rajaa M
- Alahdab Fares
- Alam Khurshid
- Alam Tahiya
- Albujeer Ammar
- Alebel Animut
- Alene Kefyalew Addis
- Alhabib Samia
- Ali Raghib
- Alijanzadeh Mehran
- Alizadeh-Navaei Reza
- Aljunid Syed Mohamed
- Alkerwi Ala'a
- Alla François
- Allebeck Peter
- Allen Christine A
- Almasi Ali
- Alonso Jordi
- Alsharif Ubai
- Altirkawi Khalid
- Alvis-Guzman Nelson
- Amare Azmeraw T
- Amenu Kebede
- Amini Erfan
- Ammar Walid
- Anber Nahla Hamed
- Anderson Jason A
- Andrei Catalina Liliana
- Androudi Sofia
- Animut Megbaru Debalkie
- Anjomshoa Mina
- Ansari Hossein
- Ansariadi Ansariadi
- Ansha Mustafa Geleto
- Antonio Carl Abelardo T
- Anwari Palwasha
- Appiah Lambert Tetteh
- Aremu Olatunde
- Areri Habtamu Abera
- Arora Monika
- Aryal Krishna K
- Asayesh Hamid
- Asfaw Ephrem Tsegay
- Asgedom Solomon Weldegebreal
- Asghar Rana Jawad
- Assadi Reza
- Ataro Zerihun
- Atique Suleman
- Atre Sachin R
- Atteraya Madhu Sudhan
- Ausloos Marcel
- Avila-Burgos Leticia
- Avokpaho Euripide F G A
- Awasthi Ashish
- Ayala Quintanilla Beatriz Paulina
- Ayele Henok Tadesse
- Ayele Yohanes
- Ayer Rakesh
- Azarpazhooh Mahmoud Reza
- Azzopardi Peter S
- Azzopardi-Muscat Natasha
- Babalola Tesleem Kayode
- Babazadeh Arefeh
- Badali Hamid
- Badawi Alaa
- Balakrishnan Kalpana
- Bali Ayele Geleto
- Banach Maciej
- Banerjee Amitava
- Banoub Joseph Adel Mattar
- Banstola Amrit
- Barac Aleksandra
- Barboza Miguel A
- Barker-Collo Suzanne Lyn
- Barrero Lope H
- Barthelemy Celine M
- Bassat Quique
- Basu Arindam
- Basu Sanjay
- Battista Robert J
- Baune Bernhard T
- Baynes Habtamu Wondifraw
- Bazargan-Hejazi Shahrzad
- Bedi Neeraj
- Beghi Ettore
- Behzadifar Masoud
- Behzadifar Meysam
- Bekele Bayu Begashaw
- Belachew Abate Bekele
- Belay Aregawi Gebreyesus
- Belay Saba Abraham
- Belay Yihalem Abebe
- Bell Michelle L
- Bello Aminu K
- Bennett Derrick A
- Bensenor Isabela M
- Benzian Habib
- Berhane Adugnaw
- Berhe Abadi Kidanemariam
- Berman Adam E
- Bernabe Eduardo
- Bernstein Robert S
- Bertolacci Gregory J
- Beuran Mircea
- Beyranvand Tina
- Bhala Neeraj
- Bhalla Ashish
- Bhansali Anil
- Bhattarai Suraj
- Bhaumik Soumyadeep
- Bhutta Zulfiqar A
- Biadgo Belete
- Biehl Molly H
- Bijani Ali
- Bikbov Boris
- Bililign Nigus
- Bin Sayeed Muhammad Shahdaat
- Birlik Sait Mentes
- Birungi Charles
- Bisanzio Donal
- Biswas Tuhin
- Bitew Helen
- Bizuneh Hailemichael
- Bjertness Espen
- Bobasa Eshetu Mulisa
- Boufous Soufiane
- Bourne Rupert
- Bozorgmehr Kayvan
- Bragazzi Nicola Luigi
- Brainin Michael
- Brant Luisa C
- Brauer Michael
- Brazinova Alexandra
- Breitborde Nicholas J K
- Briant Paul Svitil
- Britton Gabrielle
- Brugha Traolach
- Bukhman Gene
- Busse Reinhard
- Butt Zahid A
- Bärnighausen Till Winfried
- Béjot Yannick
- Cahuana-Hurtado Lucero
- Callender Charlton SKH
- Campos-Nonato Ismael R
- Campuzano Rincon Julio Cesar
- Cano Jorge
- Car Josip
- Car Mate
- Carrero Juan J
- Carter Austin
- Carvalho Félix
- Castañeda-Orjuela Carlos A
- Castillo Rivas Jacqueline
- Castro Franz
- Causey Kate
- Cercy Kelly M
- Cerin Ester
- Chaiah Yazan
- Chalek Julian
- Chang Hsing-Yi
- Chang Jung-Chen
- Chattopadhyay Aparajita
- Chattu Vijay Kumar
- Chaturvedi Pankaj
- Chiang Peggy Pei-Chia
- Chin Ken Lee
- Chisumpa Vesper Hichilombwe
- Chitheer Abdulaal
- Choi Jee-Young J
- Chowdhury Rajiv
- Christensen Hanne
- Christopher Devasahayam J
- Chung Sheng-Chia
- Cicuttini Flavia M
- Ciobanu Liliana G
- Cirillo Massimo
- Claro Rafael M
- Claßen Thomas Khaled Dwayne
- Cohen Aaron J
- Collado-Mateo Daniel
- Cooper Cyrus
- Cooper Leslie Trumbull
- Cornaby Leslie
- Cortinovis Monica
- Costa Megan
- Cousin Ewerton
- Cromwell Elizabeth A
- Crowe Christopher Stephen
- Cunningham Matthew
- Cárdenas Rosario
- Daba Alemneh Kabeta
- Dadi Abel Fekadu
- Dandona Lalit
- Dandona Rakhi
- Dang Anh Kim
- Dargan Paul I
- Daryani Ahmad
- Das Gupta Rajat
- das Neves José
- Das Siddharth K
- Dasa Tamirat Tesfaye
- Dash Aditya Prasad
- Davis Adrian C
- Davitoiu Dragos Virgil
- Davletov Kairat
- Dayama Anand
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- Zare Zohreh
- Zavala-Arciniega Luis
- Zegeye Desalegn Tegabu
- Zegeye Elias Asfaw
- Zeleke Ayalew Jejaw
- Zendehdel Kazem
- Zerfu Taddese Alemu
- Zhang Anthony Lin
- Zhang Xueying
- Zhou Maigeng
- Zhu Jun
- Zimsen Stephanie R M
- Zodpey Sanjay
- Zoeckler Leo
- Zucker Inbar
- Zuhlke Liesel Joanna J
- Ärnlöv Johan
- Çavlin Alanur
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2018
- Field of study
Background: Efforts to establish the 2015 baseline and monitor early implementation of the UN Sustainable Development Goals (SDGs) highlight both great potential for and threats to improving health by 2030. To fully deliver on the SDG aim of “leaving no one behind”, it is increasingly important to examine the health-related SDGs beyond national-level estimates. As part of the Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017), we measured progress on 41 of 52 health-related SDG indicators and estimated the health-related SDG index for 195 countries and territories for the period 1990–2017, projected indicators to 2030, and analysed global attainment. Methods: We measured progress on 41 health-related SDG indicators from 1990 to 2017, an increase of four indicators since GBD 2016 (new indicators were health worker density, sexual violence by non-intimate partners, population census status, and prevalence of physical and sexual violence [reported separately]). We also improved the measurement of several previously reported indicators. We constructed national-level estimates and, for a subset of health-related SDGs, examined indicator-level differences by sex and Socio-demographic Index (SDI) quintile. We also did subnational assessments of performance for selected countries. To construct the health-related SDG index, we transformed the value for each indicator on a scale of 0–100, with 0 as the 2\ub75th percentile and 100 as the 97\ub75th percentile of 1000 draws calculated from 1990 to 2030, and took the geometric mean of the scaled indicators by target. To generate projections through 2030, we used a forecasting framework that drew estimates from the broader GBD study and used weighted averages of indicator-specific and country-specific annualised rates of change from 1990 to 2017 to inform future estimates. We assessed attainment of indicators with defined targets in two ways: first, using mean values projected for 2030, and then using the probability of attainment in 2030 calculated from 1000 draws. We also did a global attainment analysis of the feasibility of attaining SDG targets on the basis of past trends. Using 2015 global averages of indicators with defined SDG targets, we calculated the global annualised rates of change required from 2015 to 2030 to meet these targets, and then identified in what percentiles the required global annualised rates of change fell in the distribution of country-level rates of change from 1990 to 2015. We took the mean of these global percentile values across indicators and applied the past rate of change at this mean global percentile to all health-related SDG indicators, irrespective of target definition, to estimate the equivalent 2030 global average value and percentage change from 2015 to 2030 for each indicator. Findings: The global median health-related SDG index in 2017 was 59\ub74 (IQR 35\ub74–67\ub73), ranging from a low of 11\ub76 (95% uncertainty interval 9\ub76–14\ub70) to a high of 84\ub79 (83\ub71–86\ub77). SDG index values in countries assessed at the subnational level varied substantially, particularly in China and India, although scores in Japan and the UK were more homogeneous. Indicators also varied by SDI quintile and sex, with males having worse outcomes than females for non-communicable disease (NCD) mortality, alcohol use, and smoking, among others. Most countries were projected to have a higher health-related SDG index in 2030 than in 2017, while country-level probabilities of attainment by 2030 varied widely by indicator. Under-5 mortality, neonatal mortality, maternal mortality ratio, and malaria indicators had the most countries with at least 95% probability of target attainment. Other indicators, including NCD mortality and suicide mortality, had no countries projected to meet corresponding SDG targets on the basis of projected mean values for 2030 but showed some probability of attainment by 2030. For some indicators, including child malnutrition, several infectious diseases, and most violence measures, the annualised rates of change required to meet SDG targets far exceeded the pace of progress achieved by any country in the recent past. We found that applying the mean global annualised rate of change to indicators without defined targets would equate to about 19% and 22% reductions in global smoking and alcohol consumption, respectively; a 47% decline in adolescent birth rates; and a more than 85% increase in health worker density per 1000 population by 2030. Interpretation: The GBD study offers a unique, robust platform for monitoring the health-related SDGs across demographic and geographic dimensions. Our findings underscore the importance of increased collection and analysis of disaggregated data and highlight where more deliberate design or targeting of interventions could accelerate progress in attaining the SDGs. Current projections show that many health-related SDG indicators, NCDs, NCD-related risks, and violence-related indicators will require a concerted shift away from what might have driven past gains—curative interventions in the case of NCDs—towards multisectoral, prevention-oriented policy action and investments to achieve SDG aims. Notably, several targets, if they are to be met by 2030, demand a pace of progress that no country has achieved in the recent past. The future is fundamentally uncertain, and no model can fully predict what breakthroughs or events might alter the course of the SDGs. What is clear is that our actions—or inaction—today will ultimately dictate how close the world, collectively, can get to leaving no one behind by 2030
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