53 research outputs found
Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis
- Author
- Aahlin Eirik Kjus
- Aamer Ahmed
- Aaniana Kenneth
- Ababneh Ali
- Abaliksta Tomas
- Abantanga Francis
- Abbas Athar
- Abbasy Jibran
- Abbo Olivier
- Abbott Tom
- Abbouch Meryem
- Abd El-Latif Nadia Khalid
- Abd Elkhalek Esraa
- Abd-Elmawla Manar
- Abdallah Emad
- Abdel-Aty Abdulrahman
- Abdel-Hameed Noran
- Abdel-Kader Sara Mahmoud
- Abdelaal Abdelaziz
- Abdelaty Mohamed
- Abdelazeam Anan Rady
- Abdelazim Galaleldin
- Abdelaziz Mohamed A.
- Abdelbadeai Kholoud
- Abdelfatah Afnan
- Abdelhady Samar
- Abdelhamed Rasha
- Abdelhamid Amina
- Abdelhaq Aram
- Abdelkader Mostafa
- Abdelkader Omar
- Abdelkhalek Mohamed
- Abdelmageed Eman
- Abdelmotaleb Ibrahem
- Abdelraouf Ahmed Mahmoud
- Abdelrouf Doaa Maher
- Abdelshakour Mahmoud
- Abdrabou Abdulshafi Khaled
- Abdul-Latif Saiba
- Abdulaziz Hager
- Abdulaziz Mustafa
- Abdulbagi Omar
- Abdulhakeem Eman Mahmoud
- Abdullah Mohamed Abozed
- Abdullah Nik Azim Nik
- Abdullah Noha
- Abdullahi Lawal
- Abdurrazzaaq Abdussemiu
- Abem Owusu Emmanuel
- Abiola Olajide
- Aboelella Majed
- Aboelmagd Omnia
- Aboelsoud Moustafa R.
- Aboul-Naga Mariam Saad
- Abouzaid Arwa
- Abu Qumbos Amjad
- Abu-toyour Maram
- Abubakr Marwan
- Abuowda Yousef
- Abuqwaider Eman
- Abusalem Lana
- Abushamleh Soha
- Ackom Eric
- Acquah Emmanuel
- Adam Ali
- Adam Nourhan
- Adamu Ahmed
- Adawi Ihdaa
- Adawi Mohammad
- Adebanjo Ademola
- Adebola Oluwaseyi
- Adedeji Adesina
- Adel Badr Eldin
- Adel Israa
- Adella Fidelis Jacklyn
- Adelshone Abdelrahman
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji O.
- Ademuyiwa Adesoji O.
- Adenekan Babajide
- Adeniran James
- Adeniyi Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adeyeye Ademola
- Adeyeye Ademola
- Adhitama Novia
- Adil Muhammad
- Adisa Adewale O.
- Adiyaman Can
- Adu-Aryee Niiarmah
- Afana Samah
- Agalianos Christos
- Agarwal Arnav
- Agarwal Arnav
- Agbedinu Kwabena
- Aglan Amro
- Aguado Suarez Nuria
- Aguilera Maria Lorena
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlonsou Germain
- Ahlqvist Sandra
- Ahlqvist Sandra
- Ahmed Asdaq
- Ahmed Ataa
- Ahmed Hayam
- Ahmed Hussien
- Ahmed Lopna Ahmed Mohamed
- Ahmed Sara
- Ahmed Saraibrahim
- Ahounou Ernest Yemalin Stephane
- Ajah Jonathan
- Ajai Olalekan
- Ajao Akinlabi
- Ajiboye Anthony
- Akoto Elliot
- Akpenyi Onyinye
- Al Amin Shadid
- Al Attar Samaa Mahmoud
- Al Barraw Fayez Elian
- Al Bastawis Fatema
- Al Meligy Amgad
- Al Rafati Ahmad Abdel Razaq
- Al Raouf Eman Abd
- Al Saied Ghiath
- Al Subaie Norah
- Al-Bahrani Ahmed
- Al-Buhaisi Alaa
- Al-Dakka Emad
- Al-faqawi Maha
- Al-farram Hadeel
- Al-khatib Ahmed
- Al-Marakby Dina
- Al-saqqa Sara
- Al-Saqqa Sara W.
- Al-Slaibi Ibrahim
- Al-taher Taher
- AlaaelDein Shahinaz
- Alada Muslimat
- Alakaloko Felix
- Alaloul Enas
- Alamin Shadid
- Alamoudi Mohammed
- Albiety Adel
- Alcca Ticona Willy
- Alejos Bermudez Ysabel Esthefany
- Alexander Philip
- Alexander Philip
- Alexandre Challine
- Alghamdi Ahmed
- Alghamdi Mohammed Saleh A.
- Alhady Khaled
- Alhammali Tariq
- Alhassan Basmah
- Alhazmi Wedyan
- Alherz Mohammad
- Ali Ahmed
- Ali Citra Dewi Mohd
- Ali Elsayed
- Ali Safia
- Ali Syed Abdul Wahhab Eusoffee Wan
- Ali Tebian Hassanein Ahmed
- Ali Wadah
- Alihonou Thierry
- Alis Halil
- Aliyu Halima
- Aliyu Mohammad
- Aliyu Shamsudeen
- Aljboor Khaled
- Aljiffry Murad
- Alkaaki Aroub
- Alkelani Muhammad
- Allam Meran
- Allam Yomna
- Alnaby Mohamed Hassab
- Alnusairat Aseel
- Alqahtani Saleh
- Alsaggaf Mohammed Ubaid
- Alser Osaid H.
- Alshareef Reham
- Altaf Abdulmalik
- Altamimi Abdullah
- Altamimi Afnan
- Altamini Afnan
- Altarayra Marwa
- Altibi Ahmed
- Altinel Yuksel
- Altinel Yuksel
- Altwijri Abdulaziz
- Alvi Abdul Rehman
- Aly Mohammed Yahia Mohamed
- Alyacoubi Said
- Alyahya Reem
- Alzahrani Ahmed
- Aman Nowrin F.
- Amandito Radhian
- Amandito Radhian
- Ambrona-Zafra David
- Amin Hager Abdul Aziz
- Amjad Mohammadasim
- Amoah Michael
- Amoako Joachim
- Amoako Philip Taah
- Amoako-Boateng Mabel
- Amole Isaac
- Amreia Mahmoud
- Anderson Frank
- Andika Ferry Fitriya Ayu
- Andreotti Dario
- Andress Cedar
- Andriola Valeria
- Ang Yun Lin
- Angelieri Daniele
- Anis Echaieb
- Ansaloni Luca
- Ansaloni Luca
- Ansaloni Luca
- Antezana Diego
- Anthoulakis Christos
- Antoniozzi Angelo
- Anwar Nourhan
- Anyanwu Lofty-John
- Aonzo Paolo
- Appeadu-Mensah William
- Appiah Eric Kofi
- Aquilino Fabrizio
- Arafa Omar
- Arafa Sara
- Arango Maria Clara Mendoza
- Arcudi Claudio
- Armellini Andrea
- Arnaud Alexis
- Arnaud Alexis Pierre
- Arshad Mohammad Mohsin
- Arslan Ekin
- Arsyad Hasbi Maulana
- Arthur Tom
- Aruldas Neerav
- Asar Yomna Hosny
- Asare-Bediako Kwasi
- Ashour Ahmad
- Ashour Ahmad
- Ashour Khlood
- Ashtari Morvarid
- Asi Fatema
- Asilah Siti Mohd Desa
- Assal Abdelrahman
- Asturias Sabrina
- Asumah Hamza
- Ata Ahmed
- Ata Aya Yehia
- Atiyeh Anwar
- Atkins Ebenezer Takyi
- Attia Attia
- Augestad Knut Magne
- Aviles Susan
- Avoka Anthony
- Awad Israa
- Awad Sawsan Adel
- Awadallah Salwa
- Ayandipo Omobolaji
- Aydin Mehmet Can
- Aziz Dayang Nita Abdul
- Aziz Mohamed Rezal Abdul
- Aziz Nora Abdul
- Azizeldine Mohammed G.
- Azzie Georges
- Azzis Olivier
- Baba Suleiman
- Bachri Houda
- Badawy Mahmoud
- Badenjki Mohamed Adel
- Badicel Maria
- Badr Mohamed Fawzy Mahrous
- Badwi Nermin Mohamed
- Bahar Suraya
- Baillie Katie
- Baki Bahadir Emre
- Bakr Ahmad
- Bakry Hesham Mohammed
- Bala Miklosh
- Balalis Dimitrios
- Balducci Genoveffa
- Ballouhey Quentin
- Balmaceda Ruben
- Balmaceda Ruben
- Balogun Fatai
- Baltrunas Robertas
- Baluch Fatima
- Bamford Rebecca
- Bamicha Athanasia
- Banaitis Vincas Jonas
- Bandi Ashwath
- Bandoh Dickson
- Bani-Sadar Ahmad
- Banipal Gurpreet Singh
- Baquero Suarez Alibeth Andres
- Baraka Heba
- Barendegere Venerand
- Barkolias Christos
- Barmayehvar Behrad
- Barnabas Gandau Naa
- Barrios Emmanuel
- Basilico Silvia
- Basir Elissa Rifhan Mohd
- Bassem Monica
- Bassit Khalil Abdul
- Basso Stefano M. M.
- Bayram Sefa
- Beamon Mieshia
- Bedada Alemayehu Ginbo
- BediakoBowan Antoinette
- Bekhet Amira Hassan
- Bekhet Nada Mohamed
- Beleno Alvaro Enrique Mendoza
- Belkouchi Abdelkader
- Belli Andrea
- Bello Bashir
- Benammi Sarah
- Benevento Angelo
- Bennai Redouane Mammar
- Bentounsi Zineb
- Benyaiche Chaymae
- Berti Stefano
- Bertuello Isaac
- Beuran Mircea
- Bhangu Aneel
- Bhangu Aneel
- Bhangu Anna
- Bhatnagar Ankur
- Bhopal Kamran Faisal
- Bianco Federica
- Bigaran Annamaria
- Billy Matthew
- Bin Adnan Ahmad
- Bin Hasnan Muhammad
- Bin Ismail Mohamad Jeffrey
- Birindelli Arianna
- Bisset Carly
- Bjorklund Ida
- Blacker Sarah
- Blackwell James
- Blanco Ruth
- Blanco-Colino Ruth
- Blencowe Natalie
- Bliksoen Marte
- Bluelle Rafael
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- Bode Chris
- Bodur Selim
- Boggon Adam
- Bonavia Karl
- Bonavina Luigi
- Bond-Smith Giles
- Bondin John
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- Boni Silvia
- Bonney William
- Borda-Luque Giuliano
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- Borg Elaine
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- Breaud Jean
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- Camilleri-Brennan Julian
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- Celik Saban
- Cengiz Turgut Bora
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- Cengiz Yucel
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- Chabok Abbas
- Chai Chu-Ann
- Chai Feng Yih
- Chan Luke
- Chan Tsz-Yan Katie
- Chan Xue Wei
- Charles Angeline
- Cheah Alvin Ee Zhiun
- Chen Kar Yan
- Chen Tzu-Ling
- Cheong Yih Jeng
- Chetta Nicola
- Cheung Yuk Hong Eric
- Chibuye Chali
- Chiesa Deborah
- Chilton Gareth
- Chin Pui Xin
- Chin Ye Ru
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- Chong Choon Seng
- Chong Hoong-Yin
- Choudhry Asad
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- Chowdhury Debkumar
- Chu Kathryn
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- Conci Simone
- Confalonieri Gianmaria
- Conlon Kevin C.
- Connor Katie
- Contreras Elisa
- Coompson Christian Lari
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- Corbellino Mario
- Cornick Jen
- Coronel Jazmin
- Corral Moreno Sara
- Correa Juan Camilo
- Corro-Diaz Samantha
- Costa Cecilia
- Costa-Maia Jose
- Costas-Chavarri Ainhoa
- Courboin Etienne
- Cox Daniel
- Cox Michael
- Coyoy-Gaitan Otto
- Craus-Miguel Andrea
- Cullen Fraser
- Curletti Gianluca
- Currow Chelise
- D'Amours Scott
- D'Souza Michelle S.
- Dabboor Majd
- Dabbour Kareem
- Dagoe Enoch
- Dahy Ahmed
- Dainius Edvinas
- Dakubo Jonathan
- Dalli Jeffrey
- Dally Charles
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- Danys Donatas
- Dao Weihei
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- Darwish Abdelrhman K. Z.
- Dasari Mohini
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- Drake Thomas M.
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- Fitzgerald J. Edward
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- Israelsson Leif
- Ivros Nikolaos
- Iyer Dush
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- Jabal Mohamed Sobhi
- Jaber Sahar
- Jaffry Zahra
- Jaich Robert
- Jama Guled M.
- Jamal Luai
- Janardha K. C.
- Janik Michal
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- Jayathilake A. B.
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- Khafagy Toqa
- Khalifah Eyad
- Khallaf Salwa
- Khamajeet Arvin
- Khan Maryam Ali
- Khan Roaa
- Khan Zain Ali
- Khatri Chetan
- Khoja Ahmad
- Khokha Dzianis
- Khokha Vladimir
- Khosla Shivun
- Khreishi Reem
- Khreishi Rose
- Khulu Lawrence Bongani
- Kidd Thomas
- Kinandu Kamau
- King Sebastian
- Kiran Ravi P.
- Kirby Andrew
- Kiudelis Mindaugas
- Klappenbach Roberto
- Knight Stephen
- Koay Kean Leong
- Kobal Berna Buse
- Koh Pei Ying
- Koh Sharon
- Kojo Anyomih Theophilus Teddy
- Kojo Anyomih Theophilus Teddy
- Kondrotas Paulius
- Kong Chia
- Kong Shu Ning
- Kong Victor
- Konstantina Kolonia
- Kordorwu Hope Edem Kofi
- Korkolis Dimitrios
- Kosai Nik Ritza
- Kose Emin
- Koskenvuo Laura
- Koto Modise Zacharia
- Kotobi Henri
- Kourdouli Amar
- Kourdouli Amar
- Kufeji Dorothy
- Kuliavas Justas
- Kumar Basant
- Kumar Basant
- Kumar Basant
- Kumar Sandip
- Kumar Sunil
- Kumar Sunil
- Kumwenda Dayson
- Kushwaha Sameer
- Kusi Kwasi
- Kutkevicius Juozas
- Kwakyeafriyie Prince
- Kwatiwani Chimwemwe
- Kwizera Sandrine
- Kwok Stephanie Hiu-wai
- Kyereh Martin
- Kyriazanos Ioannis
- Kyrou Georgios
- Kyziridis Dimitrios
- L'Heveder Ariadne
- La Brocca Antonella
- Ladukas Adomas
- Lagunavicius Karolis
- Lai Anthony Chuk-Him
- Lam Justin Chak Yiu
- Lam Wai Him
- Lanau Maria Isabel Villegas
- Lando Justus
- Landolfo Giovanni
- Lapitan Marie Carmela
- Larsen Johannes Wiik
- Lasek Anna
- Latif Aliang
- Laugzemys Erikas
- Laurie Kirsten
- Lauzikas Giedrius
- Law Jia Hao
- Lawal Abdulrazzaq
- Lawal Taiwo
- Lazzari Giovanni
- Lazzari Veronica
- Le Vu Thanh Hien
- Leanne Almanon Christel
- Lecompte Jean-Francois
- Lee Eu Xian
- Lee Felix
- Lee Kai Yin
- Lee Kathryn
- Lee Kuok Chung
- Lee Tien Seng Bryan
- Leone Nicoletta
- Leong Faith Qi Hui
- Leppaniemi Ari
- Leroux Julien
- Leung Ka Wai
- Leusink Astrid
- Li Ka Hin Gabriel
- Licari Leo
- Lieske Bettina
- Lieske Bettina
- Liew Ignatius
- Lilford Richard
- Lilford Richard
- Lim Hui
- Lim Jieqi
- Lim Shujing Jane
- Lim Shyang Yee
- Limoges Bernard
- Lipnickas Vytautas
- Litvin Andrey
- Liu Qinyang
- Liu Qinyang
- Ljuhar Damir
- lo Conte Annalisa
- loaloa Mohamed Reda
- Lokman Muhammad Amsyar Auni
- Longstaff Lydia
- Lopez Manuel
- Lopez Manuel
- Lorenzon Laura
- Low Xinwei
- Luc Alberto Realis
- Lucia Contreras-Vergara Ana
- Luck Joshua
- Luglio Gaetano
- Lund Jonathan
- Lytras Dimitrios
- Mabitsela Matlou Ernest
- Mabrouk Mohamed
- Macchitella Yuri
- Machain Vega Gustavo Miguel
- Maciejec Laura
- Madiba Thandinkosi
- Madkor Mona Hamdy
- Madrid Barrientos Linda Alvi
- Maffioli Anna
- Magdy Ahmed
- Magdy Eman
- Magdy Hesham
- Magdy Mohamed
- Magdy Salma
- Maghrabi Ashraf
- Magri Daniela
- Mahanty Silke
- Mahdi Shareef
- Maher Mahmoud Elkhadragy
- Mahmoud Basma
- Mahmoud Farah
- Mahmoud Hend
- Mahmoud Mohamed Ali
- Mahmoud Moustafa Ibrahim
- Mahmoud Sabry Mohy Eldeen
- Mahmoud Shady
- Maillot Betty
- Maimbo Mayaba
- Maimbo Mayaba
- Mairs Nora Grace
- Maison Kwame
- Maistry Niveshni
- Majauskyte Dovile
- Majbar Anass
- Majid Aminah Hanum Haji Abdul
- Majid Kiran
- Major Piotr
- Major Piotr
- Mak T. W. C.
- Makama Jerry
- Makupe Alex
- Malaga Barbara
- Malavenda Mariastella
- Mamdouh Rana
- Manatakis Dimitrios K.
- Manfreda Serena
- Mangiapane Mirko
- Mann Thomas
- Mano Maria Jesusa B.
- Manrique Sila George Christian
- Manriquez-Reyes Marisol
- Mansor Eman Yahya
- Mansour Salma
- Mansuri Anahita
- Mao Patrizio
- Maraie Noha
- Margaritis Michail
- Maria Garcia-Perez Jose
- Mariani Aurora
- Marret Jean-Baptiste
- Mas Robinson
- Mat Tuan Nur'Azmah Tuan
- Mata Lusi Padma Sulistianingsih
- Matheu Alejandro
- Mathew Susan Wndy
- Matos-Puig Roel
- Mattar Omar
- Matter Sara Mamdouh
- Mazelyte Ruta
- Mazrimas Povilas
- Mazzella Angela
- McGarvie Susan
- McIntosh Kirsten
- Mclean Kenneth
- Mehdi Aia
- Melo Cardozo Ramon Augusto
- Melo Renato
- Mendel Henry
- Mensah Ekow
- Meqbil Jehad
- Mericliler Meric
- Merlini David
- Mesbah Nourhan
- Migliore Marco
- Mihaljevic Andre L.
- Mihanovic Jakov
- Mikalauskas Saulius
- Mikuckyte Deimante
- Mingrone Pietro
- Minguez Garcia Javier
- Minocha Ashish
- Miranda Cesar
- Mircea Hogea
- Mironescu Aurel
- Mironescu Aurel
- Mironescu Aurel Sandu
- Mirza Shahrukh
- Mitroudi Magdalini
- Mitul Ashrarur Rahman
- Miyar de Leon Alberto
- Miyasato Hector Shibao
- Mizzi Christine
- Mizzi Sean
- Moaty Mohamed
- Mochet Sylvie
- Modolo Maria Marta
- Modolo Maria Marta
- Moe Thomas Tetens
- Moghazy Mahmoud Elsayed
- Mohamed Ahmed Rabie
- Mohamed Amna
- Mohamed Amna Mamdouh
- Mohamed Arwa
- Mohamed Bakeer
- Mohamed Fawzy
- Mohamed Mazed
- Mohamed Mohamed Abdelaty
- Mohamed Shaza Rabie
- Mohammad Aminu
- Mohammed Ahmed Rabeih
- Mohammed Amany Eldosouky
- Mohammed Hussein
- Mohammed Mustafa Mohammed
- Mohammed Sara
- Mohan Midhun
- Mok Yi Ting
- Monaghan Eimear
- Monrad-Hansen Peter Wiel
- Monteleone Michela
- Monterroso Cohen David
- Montes Irene
- Montrimaite Margarita
- Moodley Yoshan
- Moore Rachel
- Mora John Jemuel V.
- Morandi Eugenio
- Morgan Catrin
- Morshedy Eman Mohamed
- Morton Dion
- Mostafa Merna
- Mostafa Mohamed
- Moussa Omar
- Moustafa Ahmed
- Mowafy Bassant
- Mshelbwala Philip
- Msiska Nelson
- Msosa Vanessa
- Msosa Vanessa
- Muddebihal Uday
- Mueller Julia
- Mukin Annisa Dewi Fitriana
- Muktar Umar
- Mukuzunga Cornelius
- Muller Cecile
- Muntean Liviu
- Murray Alice
- Murutoglu Busra
- Musleh Aseel
- Musowoya Joseph
- Mussad Ali
- Mustafa Mousa
- Musyoka Caroluce K.
- Mutabazi Alphonse Zeta
- Mutabazi Alphonse Zeta
- Mutlu Deniz
- Mutlu Vahit
- Muzio Elena
- Myers Jonathan
- Mykoniatis Ioannis
- Nadeem Najwa
- Naess Pal Aksel
- Nagy Ghada Saied
- Nahar Sayeda Nazmum
- Najjar Mohammed
- Nanthakumaran Shayanthan
- Napolitano Lena
- Narayanan Ragavan
- Narayanan Ragavan
- Nashat Mohamed
- Nashidengo Puyearashid
- Nasir Abdulrasheed
- Nasir Wan Nurul Ain Wan Mohd
- Nasr Maha
- Nassif Dima
- Natalie Hani
- Nataraja Ram
- Natili Andrea
- Navarro Andre
- Nawawi Abrar
- Nazir Mohamed
- Ndajiwo Aliyu
- Ndajiwo Aliyu
- Ndegwa Wairimu
- Ndlovu Sibongile Ruth
- Ndwambi Phumudzo
- Negoi Ionut
- Neo Ya Theng
- Nepogodiev Dmitri
- Nepogodiev Dmitri
- Nepogodiev Dmitri
- Nessa Ashrafun
- Nestorovic Milica
- Nevieraite Viktorija
- Ng James Chean Khun
- Ng Yung Kok
- Ng Zhan Herr
- Niazi Ali Khan
- Nicholson Luke
- Nikberg Maziar
- Nikoloudis Nikolaos
- Niranjan Nithya
- Nirumal Milaksh Kumar
- Niska Karoliina
- Nita Gabriela Elisa
- Nita Gabriela Elisa
- Njokanma Iloba
- Nocito Antonio
- Noor Fazlin
- Notarnicola Margherita
- Notarnicola Margherita
- Nouh Thamer
- Noukpozounkou Bruno
- Nsengiyumva Carlos
- Ntirenganya Faustin
- Nurqistan Hazmi Dwinanda
- Nwabuoku Emeka
- Nwinee Victor
- O'Connor Donal B.
- O'Higgins Roche Marcelo
- O'Neill Stephen
- O'Shea Margaret
- Occhionorelli Savino
- Odeyemi Babatunde
- Odutola Oluwatomi
- Ogunsua Oluseyi
- Ohene-Yeboah Micheal
- Okenabirhie Ogheneochuko
- Olajide Thomas Olagboyega
- Olaolorun Akin
- Olivier James
- Olori Samson
- Oludara Mobolaji
- Olugbemi Mojolaoluwa
- Omar Mohammad Elsayed
- Omar Muhammad Fathi Waleed
- Omer Omer Abdelbagi
- Onuoha Clement
- Opoku-Agyeman Richard
- Oram Shaun
- Ortega Irene
- Ortega Irene
- Ortiz Nadia
- Orton Peter
- Osagie Olabisi
- Osei-Nketiah Samuel
- Oshati Oyindamola
- Osinowo Adedapo
- Osuoji Roland
- Oswald Dennis
- Otero-Diez Jorge L.
- Ots Riinu
- Otten Kars
- Owen Christopher
- Owusu Frank
- Ozben Volkan
- Ozkan Bahar Busra
- Ozmen Berk Baris
- Padmore Greg
- Paez Lopez Larissa Ines
- Pagano Gianluca
- Pagnozz Janet
- Palayan Kandasami
- Palliyil Madanmohan
- Palma Adrian
- Paludi Miguel Angel
- Panteli Christina
- Papageorgiou Dimitrios
- Papailia Aspasia
- Papandrea Matteo
- Papaskarlatos IasonAntonios
- Pape James
- Parakh Jehangirshaw
- Paramasivan Arjun
- Parasyris Stavros
- Pardo Gabriel
- Park Esther H. G.
- Park Jay
- Parker Robert
- Parmentier Benoit
- Parpoudi Styliani
- Parseliunas Audrius
- Pascale Giovanni
- Pascale Marco Maria
- Pasquali Sandro
- Pastora Javier
- Pata Domenica
- Pata Francesco
- Pata Francesco
- Pata Francesco
- Pata Francesco
- Pata Francesco
- Pata Giacomo
- Patel Khyati
- Patel Priya
- Patel Sanjay
- Paterson-Brown Simon
- Patoulias Ioannis
- Paul Marie
- Paulouski Dzmitry
- Paz Galvez Carlos
- Pazuskis Matas
- Pektas Ahmet Murat
- Pellino Gianluca
- Peltrini Roberto
- Pena Lenin
- Perenyei Miklos
- Perera James
- Perera James
- Perez Rojas Angel David
- Perino Martina
- Peros Georgios
- Perrotta Gerardo
- Pertersen Servin Gustavo Rodolfo
- Pesenti Giovanni
- Petrikenas Steponas
- Peycelon Matthieu
- Pezas Theodore
- Picardo Antonio
- Picardo Antonio
- Picciariello Arcangelo
- Pineno-Flores Cristina
- Pinkney Thomas
- Pinkney Thomas
- Pinnagoda Kalitha
- Ploski Jennifer
- Pluke Kent
- Podevin Guillaume
- Poh Keat-Seong
- Popa Mariuca
- Popoola Ademola
- Poskus Tomas
- Poskus Tomas
- Poskus Tomas
- Post Nathan
- Prins Marloes
- Pronin Savva
- Prudhomme Thomas
- Psarianos Kyriakos
- Pugliesi Thays Brunelli
- Pujol-Cano Natalia
- Purwaningsih Nurlaila Ayu
- Puyana Juan
- Qaissieh Ahmad
- Qawasmi Israa
- Qenawy Mostafa
- Quek Roy
- Qureshi Ahmad Uzair
- Qureshi Ahmad Uzair
- Qureshi Mobeen
- Qurie Khalid
- Rackauskas Rokas
- Radkowiak Dorota
- Radojkovic Milan
- Rahantasoa Finaritra Casimir Fleur Prudence
- Rahmah Dina Faizatur
- Rajan Reynu
- Rajmohan Shivanchan
- Rakha Ibrahim
- Ramadan Menna Tallah
- Ramos Perez Virginia
- Ramos-De la Medina Antonio
- Ramos-De la Medina Antonio
- Ramos-De la Medina Antonio
- Raptis Dimitri Aristotle
- Raptis Dmitri
- Rashad Eman
- Rashed Ahmed M.
- Rasoaherinomenjanahary Fanjandrainy
- Rath Max
- Ravishankar Ramanish
- Rayne Sarah
- Rayne Sarah
- Rayne Sarah
- Rayne Sarah
- Raza Ahmed
- Raza Awais
- Raza Ibrahim
- Razuri Cesar
- Razzaque Joyeta
- Reali Claudia
- Recinos Gustavo
- Recinos Gustavo
- Reda Amira
- Reda Aya
- Redgrave Natalie
- Redota Menold Archee P.
- Reece-Smith Alex
- Reinisch Katharina
- Reinsoo Arvo
- Rekhis Syrine
- Renaux-Petel Mariette
- Restrepo Ivan Mendoza
- Reunis Elke
- Rezq Asmaa
- Riauka Romualdas
- Riaz Muhammed Masood
- Ribaldi Sergio
- Rickard Jennifer
- Rida Ahmed Hossam Eldin Fouad
- Riente Francesco
- Rinaldi Anna
- Ringressi Maria Novella
- Ripa Matteo
- Riswan Nur Zulaika
- Rob Zakaria
- Robert Elsa
- Robledo-Rabanal Alina
- Rocke Alistair
- Rod Julien
- Rod Julien
- Rodicio Joseluis
- Rodriguez Xianelle
- Roman Velasquez Armando Jose
- Romani Diego
- Romani Diego
- Rommaneh Muna
- Roodt Liana
- Rosales Javier
- Rosello Olivier
- Roslani April Camilla
- Rossi Davide
- Roszkowski Rafal
- Rotunno Giuseppe
- Rouse Tyler
- Roy Chloe
- Roy Swapnil
- Rubinkiewicz Mateusz
- Ruiz Panez Walter
- Ruiz-Tova Jaime
- Rulie Anthonius Santoso
- Runigamugabo Emmy
- Russo Alfio Alessandro
- Rutkowski Wiktor
- Ruzzenente Andrea
- Saad Abdalla Gamal
- Saad Hala
- Saad Hanan Adel
- Saad Mahmoud M.
- Saad Reham
- Saadeh Rana
- Saami Mahmoud
- Saar Sten
- Sabe Ahmad
- Sabe Ahmad Khaled
- Sabour Fahd Abdel
- Sacco Michele
- Sacco Rosario
- Saeed Manar
- Sahbaz Nuri Alper
- Sahel Sarah
- Saidbadr Ahmed
- Sakr Ahmad
- Salah Asmaa
- Salah Maram
- Salah Mohamed
- Salah Osama Mohamed
- Salama Mahmoud
- Salama Yahya
- Salamone Giuseppe
- Salcedo Jannin
- Sale Danjuma
- Saleh Amr Ahmed
- Salem Hosni Khairy
- Salem Hosni Khairy
- Salem Hosni Khairy
- Salem Menatalla
- Salem Mohammed Mousa
- Sallam Abd Elkhalek
- Salleh Afizah
- Sallinen Ville
- Salma Mahmoud
- Salma Umme
- Salman Ayman
- Salusso Paola
- Sam Zi Hao
- Samalavicius Narimantas E.
- Samison Luc Herve
- Sammarco Giuseppe
- Sammut Keith
- Samson Garba
- Samuel Sani Ali
- Samy Mostada
- Samy Mostafa
- Sanad Aly
- Sanchez Rosenberg Guillermo
- Sanchez Samaniego Camila
- Sanchez Belen
- Sanchez Diana
- Sander Anthony
- Sandler Simone
- Sandoval Barrantes Ana Maria
- Sanni Hakeem Ayomi
- Sanz Sandra
- Sapci Ipek
- Saqlain Muhammad
- Sarafilovic Hannah
- Saraste Deborah
- Saravia Fridiz
- Sasia Diego
- Saw Jian Er
- Sayed Farrag
- Sayed Marwa
- Scalabre Aurelien
- Scalabre Aurelien
- Schadde Erik
- Schiavone Roberto
- Schmid Roger
- Schmitt Francoise
- Schuetz Tobias
- Schultz Johannes Kurt
- Scicluna Ruth
- Segovia Lohse Helmut Alfredo
- Seisay Sam
- Selvaggi Francesco
- Selvaggi Lucio
- Semeda Nourhan
- Semiz Anil
- Sena-Ruiz Fatima
- Senanayake Kithsiri J.
- Setiawan Jonny
- Seto Djifid Morel
- Seyoum Nebyou
- Sfougaris Dimitrios
- Shachykava Tatsiana
- Shaharuddin Shahadatul
- Shahbaz Aized Raza
- Shaheen Alaa
- Shahine Ahmed
- Shahzad Noman
- Shaikh Nihaal
- Shakshouk Hend Adel Gawad
- Shalabi Ahmad
- Shalaby Mahmoud
- Shalaby Mostafa
- Shamasneh Ala
- Shamsedine Ahmed W.
- Sharma Abhishek
- Sharpin Claire
- Shatkar Veeranna
- Shaw Catherine A.
- Shaw Catherine A.
- Shawky Martina Yusuf
- Shawqi Muhammad
- Sheshe Abdurrahaman
- Sheta Ahmed
- Shillito Sam
- Shiwani Haaris A.
- Sholadoye Tunde
- Shrimanker Nikhita
- Shu Sebastian
- Shu Sebastian
- Shu Sebestian
- Shubianok Maryna
- Shwky Ayman
- Siaw Jia Yng
- Sierra Sebastian
- Sigurdadottir Johanna
- Sii Samuel S. Y.
- Sileri Pierpaolo
- Silvestri Vania
- Simioni Andrea
- Simutis Gintaras
- Skerritt Clare
- Slapelyte Evelina
- Sleem Ahmad Saber
- Sleem Mohamed
- Smart Neil
- Smart Neil
- Smedley Alexander
- Smith Christopher
- Sobnach Sanju
- Sokratous Arestis
- Solaini Leonardo
- Solar Garcia Lorena
- Soldevila-Verdeguer Carla
- Soledad Merlo Maria
- Soley Rafael
- Soliman Abdelrahman
- Soliman Ahmed
- Soliman Noha Abdullah
- Soliman Nourhan
- Soliman Samar
- Soliman Yasmin
- Sollazzo Viviana
- Soon Wai Cheong
- Soreide Jon Arne
- Soreide Kjetil
- Soreide Kjetil
- Souaibou Yacoubou Imorou
- Soulou Vasiliki
- Spence Richard
- Spence Richard
- Spence Richard
- Spence Richard
- Sproule Lorraine
- Srinivasan Ravi
- Sroor Fathy
- Sruogiene Elena Zdanyte
- Steccanella Francesca
- Stefanopoulos Anastasios
- Stock Simon
- Stoddart Michael
- Stoddart Michael
- Stourton Frederick
- Strupas Kestutis
- Stuva Jessica
- Styles Kristian
- Suarez Aida
- Subocius Andrejus
- Sund Malin
- Suresh Sukrit
- Sutandi Nathania
- Suyadi Arlindawati
- Swaroop Mamta
- Syibrah Khuzaimah Zahid
- Tabiri Stephen
- Tabiri Stephen
- Tabiri Stephen
- Tabiri Stephen
- Tackie Enoch
- Taddei Antonio
- Tahboub Haya
- Taher Ayman
- Taher Mustafa Mohammed
- Taieb Chouikh
- Taiwo Agboola
- Taiwo Ogechukwu
- Talaat Muhammed
- Tale Luis
- Talving Peep
- Talving Peep
- Tan Charlene
- Tan Choy Ling
- Tan Joel Kin
- Tan Keith Say Kwang
- Tan Ryan Choon Kiat
- Tan Yee Wen
- Tan Yi Koon
- Tang Lingshan
- Tani Sobhana Iftekhar
- Tansoker Ilkan
- Tarek Adham
- Tarek Dina
- Targa Simone
- Tariq Sherif
- Tata Mahadevan Deva
- Tawfik Badreldin Adel
- Tawfik Gehad
- Teasdale Ella
- Teasdale Ella
- Teasdale Ella
- Tedeschi Umberto
- Tembo Thelma
- Tennakoon Athula
- Teo Shuang Yi
- Ter Eunice Zuling
- Tew Yong Yong
- Tew Yong Yong
- Thabet Waleed
- Thalgaspitiya S. P. B.
- Theodosopoulos Theodosios
- Thollot Aurore
- Thorarinsdottir Hildur
- Thorell Anders
- Timothy Oyediran Kehinde
- Ting Jesse Ron Swire
- To Kathleen
- Tolonen Matti
- Tolotra Todisoa Emmanuella Christina
- Tomas Kadir
- Tori Sayeeda Aktar
- Toribio Orbegozo Pedro Angel
- Torrance Hew D.
- Torres Cardozo Jorge
- Torres Rodriguez Servio Tulio
- Toto Omer Faruk
- Townsend Dominic
- Trompetto Mario
- Tselos Angelos
- Tshisola Serge Kapenda
- Tugnoli Gregorio
- Tun Myint
- Turati Luca
- Turkustani Sondos
- Turpo Espinoza Kenny
- Turpo Espinoza Kevin
- Tutino Roberta
- Tverskis Zygimantas
- Tyler Robert
- Tze R. Goh Ern
- Tzikos Georgios
- Ubiali Paolo
- Ukwenya Yahaya
- ul Razi Syed Asaat
- Ulusahin Mehmet
- Upadhyaya Vijaid
- Urbonas Tomas
- Urniezius Zigmantas
- Uscinas Laimonas
- Uzabumwana Norbert
- Vaicius Arturas
- Valcarcel-Saldana Maria
- Valioulis Ioannis
- Van Der Naald Niels
- Van Niekerk Michael
- Van Straten Stephanie
- Vargas Marvin
- Vartanoglu Talar
- Vartic Mihaela
- Vasquez Giorgio
- Vasquez Idelso
- Veen Torhild
- Velasquez Ricardo
- Venclauskas Linas
- Vendramin Elena
- Venskutonis Donatas
- Venskutonis Donatas
- Verbeek Anna
- Vergara Mejia Angelica Genoveva
- Verjee Azmina
- Vermaas Maarten
- Vicario Erika
- Vicenta Collado Maria
- Vida Lucian Corneliu
- Vilcinskas Mantas
- Villalobos Santiago
- Violi Paola
- Visinskas Petras
- Voulgaris Evangelos
- Wael Noha
- Wakefield Rebecca
- Waledziak Maciej
- Walker Michael
- Walker Nathan
- Walls Luke
- Walsh Michael
- Waqar Muhammad
- Warren Oliver
- Waterman Ade
- Werder Gabriela
- Whitaker John
- White Rebecca
- Whitehurst Katharine
- Wiborg Joachim
- Widiastini T. Ariani
- Widmer Lukas Werner
- Wijayarathna L. S.
- Williams Omolara
- Wilson Ling
- Wilson Michael
- Wilson Michael
- Wimalge P. M. S. N.
- Wogensen Fredrik
- Wolf Bernhard
- Wondoh Paul
- Wondoh Paul
- Wong Chui Yee
- Wong Francisca
- Wong Hong Yee
- Wood Greta
- Worku Mengistu
- Worku Tewodros
- Wright Naomi
- Yahaya Muhammad Taqiyuddin
- Yakubu Musah
- Yam Sir Young
- Yang James
- Yap Suhhuey
- Yau Jih Dar
- Ye Joselyn
- Yeang Li Jing
- Yeung Man Hon Andrew
- Yifieyeh Abiboye
- Yildirim Reyyan
- Yip Chingwan
- Ymeri Shpetim
- Yoganathan Pigeneswaren
- Yolcu Sinem
- Yong Guo Liang
- Younis Abobaker
- Youssef Mohamed
- Yuksek Mahmut Arif
- Yusufali Taha
- Zaa'treh Rula
- Zadoroznas Antanas
- Zahran Diaaaldin
- Zakaria Esraay
- Zakaria Mahmoud
- Zakaria Yehia
- Zaki Ahmed
- Zammit Stefan
- Zampitis Nikolaos
- Zani Augusto
- Zani Augusto
- Zanini Nicola
- Zapata Felipe
- Zarb Ciskje
- Zeta Solis Ludwing Alexander
- Zielinski Martin
- Zilinskas Justas
- Zilinskas Justas
- Zilinskas Justas
- Zilinskiene Reda
- Ziubryte Greta
- Zohair Ahmed
- Zuber Markus
- Zuk Grzegorz
- Zulkifli Athirah
- Zumbuhl Lucius
- Publication venue
- Elsevier
- Publication date
- 01/06/2003
- Field of study
BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London
Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study
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- Zupan D.
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2022
- Field of study
Background Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide.Methods A multimethods analysis was performed as part of the GlobalSurg 3 study-a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital.Findings Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3.85 [95% CI 2.58-5.75]; p<0.0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63.0% vs 82.7%; OR 0.35 [0.23-0.53]; p<0.0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer.Interpretation Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
- Author
- Adams Mark
- Adolfsson Rolf
- Agartz Ingrid
- Agerbo Esben
- Al Eissa Mariam
- Albus Margot
- Alexander Madeline
- Alizadeh Behrooz Z
- Alptekin Köksal
- Als Thomas D
- Amin Farooq
- Andreassen Ole A
- Arango Celso
- Arolt Volker
- Arrojo Manuel
- Atbaşoğlu Eşref Cem
- Athanasiu Lavinia
- Atkinson Elizabeth G
- Awasthi Swapnil
- Ayub Muhammad
- Azevedo Maria Helena
- Bacanu Silviu A
- Bass Nicholas J
- Baune Bernhard T
- Begemann Martin
- Belangero Sintia Iole
- Belliveau Richard A
- Bene Judit
- Benner Christian
- Benyamin Beben
- Bergen Sarah E
- Bertolino Alessandro
- Bigdeli Tim B
- Black Donald W
- Blasi Giuseppe
- Bobes Julio
- Bonassi Stefano
- Braff David
- Bramon Elvira
- Braun Alice
- Bray Nicholas J
- Breen Gerome
- Bressan Rodrigo Affonseca
- Bromet Evelyn J
- Bruggeman Richard
- Bryois Julien
- Buccola Nancy G
- Buckley Peter F
- Buckner Randy L
- Buxbaum Joseph D
- Bybjerg-Grauholm Jonas
- Byerley William F
- Børglum Anders D
- Cahn Wiepke
- Cairns Murray J
- Calkins Monica E
- Campion Dominique
- Carr Vaughan J
- Castle David
- Catts Stanley V
- Cervilla Jorge A
- Chambert Kimberley D
- Chan Raymond CK
- Chaumette Boris
- Chen Chia-Yen
- Chen Wei J
- Cheng Wei
- Cheung Eric FC
- Chong Siow Ann
- Cichon Sven
- Cloninger C Robert
- Cohen David
- Collier David A
- Consoli Angèle
- Cordeiro Quirino
- Corvin Aiden
- Costas Javier
- Crespo-Facorro Benedicto
- Curtis Charles
- Curtis David
- Daly Mark J
- Davidson Michael
- Davis Kenneth L
- de Haan Lieuwe
- Degenhardt Franziska
- DeLisi Lynn E
- Demontis Ditte
- Dennison Charlotte A
- Dickerson Faith
- Dikeos Dimitris
- Dinan Timothy
- Djurovic Srdjan
- Domenici Enrico
- Donohoe Gary
- Duan Jubao
- Ducci Giuseppe
- Dudbridge Frank
- Ehrenreich Hannelore
- Eriksson Johan G
- Escott-Price Valentina
- Esko Tõnu
- Fanous Ayman H
- Faraone Stephen V
- Fañanás Lourdes
- Fiorentino Alessia
- Forstner Andreas
- Forti Marta Di
- Frank Josef
- Freedman Robert
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- Fromer Menachem
- Frustaci Alessandra
- Gadelha Ary
- Galletly Cherrie
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- Gareeva Anna
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- Gennarelli Massimo
- Genovese Giulio
- Gershon Elliot S
- Giannitelli Marianna
- Giegling Ina
- Gill Michael
- Giusti-Rodríguez Paola
- Glatt Stephen J
- Godard Stephanie
- Goldstein Jacqueline I
- Golimbet Vera
- González Peñas Javier
- González-Pinto Ana
- Gopal Srihari
- Gratten Jacob
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- Greenwood Tiffany A
- Grove Jakob
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- Hong Kyung Sue
- Hougaard David M
- Howrigan Daniel P
- Huang Hailiang
- Hultman Christina M
- Hwu Hai-Gwo
- Hyman Steven E
- Ikeda Masashi
- Indonesia Schizophrenia Consortium
- Iwata Nakao
- Iyegbe Conrad
- Jablensky Assen V
- Joa Inge
- Julià Antonio
- Jönsson Erik G
- Kahn René S
- Kam-Thong Tony
- Kamatani Yoichiro
- Karachanak-Yankova Sena
- Kebir Oussama
- Keller Matthew C
- Kelly Brian J
- Kendler Kenneth S
- Kennedy James L
- Khrunin Andrey
- Khusnutdinova Elza
- Kim Minsoo
- Kim Sung-Wan
- Kirov George
- Klovins Janis
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- Kondratiev Nikolay
- Konte Bettina
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- Kubo Michiaki
- Kusumawardhani Agung
- Kuzelova-Ptackova Hana
- Kučinskas Vaidutis
- Kučinskiene Zita Ausrele
- Kähler Anna K
- Lam Max
- Landi Stefano
- Laurent-Levinson Claudine
- Lazzeroni Laura C
- Lee Jimmy
- Lee Phil H
- Legge Sophie E
- Lehrer Douglas S
- Lencer Rebecca
- Lencz Todd
- Lerer Bernard
- Levinson Douglas F
- Li Miaoxin
- Li Qingqin S
- Li Zhiqiang
- Lieberman Jeffrey
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- Limborska Svetlana
- Liu Chih-Min
- Liu Jianjun
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- Lubinski Jan
- Luykx Jurjen J
- Lynham Amy
- Lönnqvist Jouko
- Macek Milan
- Mackinnon Andrew
- Magnusson Patrik KE
- Magnusson Sigurdur
- Maher Brion S
- Maier Wolfgang
- Malaspina Dolores
- Malhotra Anil K
- Malhotra Dheeraj
- Mallet Jacques
- Marder Stephen R
- Marsal Sara
- Martin Alicia R
- Martorell Lourdes
- Mattheisen Manuel
- McCarley Robert W
- McCarroll Steven A
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- McGrath John J
- McIntosh Andrew
- McQuillin Andrew
- Medeiros Helena
- Meier Sandra
- Melegh Bela
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- Metspalu Andres
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- Milani Lili
- Milanova Vihra
- Mitjans Marina
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- Molina Esther
- Molto María Dolores
- Mondelli Valeria
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- Morgan Vera A
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- Myin-Germeys Inez
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- Neil Amanda L
- Nenadić Igor
- Nestadt Gerald
- Nikitina-Zake Liene
- Nimgaonkar Vishwajit
- Nordentoft Merete
- Noto Cristiano
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- O'Brien Niamh Louise
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- Oh Sang-Yun
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- Owen Michael J
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- Palotie Aarno
- Panagiotaropoulou Georgia
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- Pfuhlmann Bruno
- Pietiläinen Olli
- Pimm Jonathan
- Pirinen Matti
- Pocklington Andrew J
- Porteous David
- Posthuma Danielle
- Powell John
- PsychENCODE
- Psychosis Endophenotypes International Consortium
- Pulver Ann E
- Qi Ting
- Qin Shengying
- Quattrone Diego
- Quested Digby
- Radant Allen D
- Rampino Antonio
- Rapaport Mark H
- Rautanen Anna
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- Rujescu Dan
- Rutten Bart PF
- Saka Meram C
- Saker-Delye Safaa
- Salomaa Veikko
- Sanders Alan R
- Sanjuan Julio
- Santoro Marcos Leite
- Savitz Adam
- Schall Ulrich
- Schizophrenia Working Group of the Psychiatric Genomics Consorti
- Schulze Thomas G
- Schwab Sibylle G
- Scott Rodney J
- Seidman Larry J
- Serretti Alessandro
- Sham Pak C
- Sharp Sally Isabel
- Shi Jianxin
- Shi Yongyong
- Sidorenko Julia
- Siever Larry J
- Sigurdsson Engilbert
- Silverman Jeremy M
- Sim Kang
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- Slominsky Petr
- Smoller Jordan W
- So Hon-Cheong
- Sobell Janet L
- St Clair David
- Stahl Eli A
- Stain Helen J
- Steen Nils Eiel
- Stefansson Kari
- Stefánsson Hreinn
- Steixner-Kumar Agnes A
- Stone William S
- Straub Richard E
- Streit Fabian
- Strengman Eric
- Stroup T Scott
- Stögmann Elisabeth
- Subramaniam Mythily
- Sugar Catherine A
- Sullivan Patrick F
- Suvisaari Jaana
- Svrakic Dragan M
- Swerdlow Neal R
- SynGO Consortium
- Szatkiewicz Jin P
- Söderman Erik
- Ta Thi Minh Tam
- Takahashi Atsushi
- Terao Chikashi
- Thibaut Florence
- Toncheva Draga
- Tooney Paul A
- Torretta Silvia
- Tosato Sarah
- Trubetskoy Vassily
- Tsuang Debby W
- Tsuang Ming T
- Tura Gian Battista
- Turetsky Bruce I
- Vaaler Arne
- van Amelsvoort Therese
- van Os Jim
- van Winkel Ruud
- Vassos Evangelos
- Vawter Marquis P
- Veijola Juha
- Verhage Matthijs
- Vilella Elisabet
- Visscher Peter M
- Voloudakis Georgios
- Waddington John
- Walter Henrik
- Walters James TR
- Wang Shi-Heng
- Watanabe Kyoko
- Waterreus Anna
- Webb Bradley T
- Weinberger Daniel R
- Weiser Mark
- Werge Thomas
- Wildenauer Dieter B
- Williams Nigel M
- Witt Stephanie H
- Wormley Brandon K
- Wray Naomi R
- Wu Jing Qin
- Wu Yang
- Xu Shuhua
- Xu Zhida
- Yang Jian
- Yolken Robert
- Yu Xin
- Yue Weihua
- Zai Clement C
- Zeng Jian
- Zhang Wen
- Zhou Wei
- Zhu Feng
- Zimprich Fritz
- Üçok Alp
- Publication venue
- NATURE PORTFOLIO
- Publication date
- 21/04/2022
- Field of study
Schizophrenia has a heritability of 60-80%1, much of which is attributable to common risk alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with schizophrenia and 243,649 control individuals, we report common variant associations at 287 distinct genomic loci. Associations were concentrated in genes that are expressed in excitatory and inhibitory neurons of the central nervous system, but not in other tissues or cell types. Using fine-mapping and functional genomic data, we identify 120 genes (106 protein-coding) that are likely to underpin associations at some of these loci, including 16 genes with credible causal non-synonymous or untranslated region variation. We also implicate fundamental processes related to neuronal function, including synaptic organization, differentiation and transmission. Fine-mapped candidates were enriched for genes associated with rare disruptive coding variants in people with schizophrenia, including the glutamate receptor subunit GRIN2A and transcription factor SP4, and were also enriched for genes implicated by such variants in neurodevelopmental disorders. We identify biological processes relevant to schizophrenia pathophysiology; show convergence of common and rare variant associations in schizophrenia and neurodevelopmental disorders; and provide a resource of prioritized genes and variants to advance mechanistic studies
The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study
- Author
- Abadia M
- Abassy J
- Abate E
- Abbott Tom EF
- Abdelaal Samir A
- Abdeldayem H
- Abdelkabir M
- Abdelsamed A
- Abdulwahed E
- Abiyere H
- Abou Chaar MK
- Abukhalaf SA
- Abukhalaf Sadi
- Adamina Michel
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji O
- Adeyeye A
- Adisa Adewale
- Afzal MF
- Agarwal Arnav
- Aggarwal M
- Agnes A
- Agostini C
- Agrawal A
- Agrawal N
- Agresta F
- Aguiar Junior S
- Ahmed A
- Ahmed K
- Ahmed Nafees R
- Ahmed Z
- Ahn JH
- Aime A
- Akhtar N
- Akkulak Murat
- Akrivou D
- Al Abdallah M
- Al Riyami S
- Al Sayed M
- Al-Masri M
- Al-Najjar H
- Al-Slaibi I
- Alaa S
- Alakaloko Felix
- Alameer Ehab
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- Alawneh F
- Albertsmeier M
- Albertsmeier Markus
- Alderson Derek
- Aldokali N
- Alemanno G
- Alfieri S
- Algallai M
- Ali AA
- Alkadiki Ghadah Z
- Almaadany Faraj S
- Almeida AC
- Almeida-Reis R
- Almezghwi H
- Almond Max
- Alrahawy M
- Alser Osaid
- Alshaar Muhammad
- Alshareea E
- Alshareef K
- Alshryda Sattar
- Alsoufi A
- Altamirano Riquoir C
- Altomare DF
- Altomi I
- Alurralde C
- Alvarez MR
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- AlZAEDE S
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- Amaral MJ
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- Publication venue
- 'Royal College of Obstetricians & Gynaecologists (RCOG)'
- Publication date
- 01/06/2022
- Field of study
AIM: The SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery. METHODS: This was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January-April 2020). Surgical delay was defined as an operation taking place more than 4 weeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin. RESULTS: Overall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4 weeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, P = 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, P < 0.001). After adjustment, delay was not associated with a lower rate of complete resection (OR 1.18, 95% CI 0.90-1.55, P = 0.224), which was consistent in elective patients only (OR 0.94, 95% CI 0.69-1.27, P = 0.672). Longer delays were not associated with poorer outcomes. CONCLUSION: One in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease
Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy
- Author
- Aahlin EK
- Aamer A
- Aaniana K
- Ababneh A
- Abaliksta T
- Abantanga F
- Abantanga F
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- Abbasy J
- Abbo O
- Abbo O
- Abbott T
- Abbouch M
- Abd El Galeel A
- Abd El Hameed OS
- Abd El Hamid N
- Abd El Salam Y
- Abd El Slam M
- Abd El-Salam F
- Abd Elrasoul Y
- Abd-Elmawla M
- Abd-Elrasoul Y
- Abdallah E
- Abdallah E
- Abdel-Aty A
- Abdel-Hameed N
- Abdel-Kader SM
- Abdel-Wahab NYE
- Abdelaal A
- Abdelaty M
- Abdelazeam AR
- Abdelazim G
- Abdelaziz MA
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- Abdelfatah A
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- Asele FA
- Ashour A
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- Asturia S
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- Atiyeh A
- Atkins ET
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- Awad SA
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- Awuku-Asabre J
- Ayad S
- Ayandipo O
- Ayandipo OO
- Aydin MC
- Ayyar S
- Aziz DNA
- Aziz MRA
- Aziz NA
- Azizeldine MG
- Azmitia Mendizabal CA
- Azodo IA
- Azzie G
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- Baba S
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- Badawy M
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- Badr A
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- Bamicha A
- Bamicha A
- Banaitis VJ
- Bandi A
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- Bani-Sadar A
- Banipal GS
- Baraka H
- Barakat SAE
- Barendegere V
- Barker T
- Barkolias C
- Barmayehvar B
- Barnabas GN
- Barnacle J
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- Barrionuevo Ojeda RR
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- Barros De Castro Segundo LC
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- Barry J
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- Bassit KA
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- Bedada AG
- Bediako-Bowan A
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- Beisa V
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- Bekhet AH
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- Benevento A
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- Benons N
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- Bezerra Morais PA
- Bezzina M
- Bhang A
- Bhangu A
- Bhangu A
- Bhargava A
- Bharj IS
- Bhat S
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- Bhopal KF
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- Bianco F
- Bigaran A
- Billy M
- Bin Adnan A
- Bin Hasnan M
- Bin Ismail MJ
- Bin Mahamood A
- Birindelli A
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- Blacker S
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- Cheung YHE
- Chew LS
- Chhabra S
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- Chiesa D
- Chilton G
- Chin PX
- Chin YR
- Chiu S
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- Chiu SMY
- Choi J
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- Chong BFHK
- Chong CL
- Chong CL
- Chong CL
- Chong CS
- Chong H-Y
- Chong HY
- Choudhry A
- Chow CYN
- Chowdhury A
- Chowdhury D
- Chu K
- Chun A
- Chun T
- Chung KJ
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- Delforge X
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- Deputy M
- Der Y
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- Despotidis V
- Desta S
- Deutschmann P
- Devadasar GH
- Dharamshi HA
- Dhillon D
- Di Franco F
- Di Martino N
- Di Saverio S
- Di Saverio S
- Diab A
- Diaconescu B
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- Diaz Vico T
- Diaz-Jover P
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- Dione Parreno-Sacdalan M
- Dissanayake T
- Djivoh F
- Domini E
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- Donoghue D
- Dorani RMNR
- Dorisme A
- dos Santos DV
- Dossou F
- Doughan S
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- Dousset B
- Dragatas D
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- Driscoll A
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- Du Toit F
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- Duhoranenayo D
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- El Deen KN
- El Gendy A
- El Gendy NH
- El Halawany M
- El Jamassi A
- El Kashash A
- El Kholy A
- El Magd AA
- El Mesery S
- El Sayed GS
- El Sayed IM
- El Shoura Y
- El-badawy HA
- El-Dien KS
- El-Dien KS
- El-Din RA
- El-Din SA
- El-Gizawy E
- El-Hamouly AS
- El-Kashef H
- El-Latif NK
- El-Ma'doul AS
- El-Rabaa S
- El-Sagheer N
- El-Sawy A
- El-Sehily A
- El-Shahat NS
- El-Sheemy H
- El-Taher E
- Elabdin HZ
- Elashmawy M
- Elashry R
- Elazab A
- Elazayem AA
- Elazoul M
- Elbanby E
- Elbanby ES
- Elbatahgy A
- Elbe P
- Elbermawy M
- Elbisomy KH
- Eldafrawy M
- Eldamaty L
- Eldeeb AZ
- Eldeen EA
- Eldin MAB
- EldosoukyMohammed A
- Elebute O
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- Elena G
- Elfarargy A
- Elfeki H
- Elfeki H
- Elfiky M
- Elfil M
- Elfouly N
- Elfouly N
- Elfouly Y
- Elfouly Y
- Elgebaly A
- Elgendy AH
- Elgendy FI
- Elgheriany M
- Elhadad A
- Elhadary NM
- Elhadry S
- Elhalawany E
- Elhamouly S
- Elhelbawy MS
- Elhendawy A
- Elhendawy AOA
- Elhoseny G
- Elhusseiny AAE
- Elizabeth Lopez C
- Elkadsh I
- Elkady F
- Elkelany A
- Elkelany A
- Elkelany A
- Elkelany A
- Elkhadrawi M
- Elkhalek EA
- Elkholy A
- Elkholy SS
- Elkolaly SS
- Elkorashy AM
- Ellison Q
- Elmashala A
- Elmasry M
- Elmelegy R
- Elmihy S
- Elnagar A
- Elnajjar MA
- Elnemr AE
- Elrazek AA
- Elsabbagh N
- Elsameea AA
- Elsawahly DME
- Elsawy A
- Elsayed M
- Elsayed M
- Elsayed N
- Elsayed NAR
- Elsayed ZM
- Elsebaaye AO
- Elsehimy M
- Elsemelawy R
- Elshaar M
- Elshaer K
- Elshaer M
- Elshaer M
- Elshafay AE
- Elshami M
- Elshanwany S
- Elsharkawy AA
- Elsheikh S
- Elsherbiney S
- Elsherbiny AS
- Elsherif FA
- Elshobary M
- Elsiddig M
- Elsobky S
- Elsorogy DEAA
- Elwaey A
- Elwakil H
- Elwan A
- Elwan A
- Elwy E
- Elzahed N
- Elzayat I
- Elzayat M
- Elzayyat I
- Elzowawi F
- Emadeldin D
- Emadeldin H
- Emara E
- Emile S
- Eng C
- English W
- Esam A
- Escalante Salas MDC
- Espin-Basany E
- Espinoza F
- Essam A
- Essam AA
- Essam M
- Essoun S
- Esteban E
- Estee MM
- Estupinian S
- Etchill E
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- Etienne S
- Etman M
- Etwire V
- Evajelista CV
- Evans D
- Evans E
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- Eyssartier E
- Ezzat E
- Ezzat T
- Faboya O
- Faccincani R
- Fadel A
- Fahiem A
- Fahim M
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- Falzon M
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- Farhangmehr N
- Farinella E
- Farmakis K
- Farooq T
- Farouk SAM
- Farquharson A
- Farrugia A
- Farrugia A
- Faruq A
- Fathy AM
- Fattah AA
- Fatuga A
- Faturoti O
- Faturoti O
- Faure A
- Fautz T
- Favero A
- Fawzy A
- Feidantsis T
- Felipe CO
- Fergany A
- Fergusson SJ
- Fergusson SJ
- Fergusson SJ
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- Fermani C
- Fermani CG
- Fernandes C
- Fernandez C
- Fernandez-Bueno F
- Fernandez-Vega L
- Ferousis C
- Ferrero E
- Fievet L
- Filatau A
- Findlay-Cooper K
- Firdouse M
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- Firwana A
- Fitsum A
- Fitzgerald JE
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- Florez Farfan ES
- Foco M
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- Fontana T
- Foo CC
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- Forno W
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- Fowler AJ
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- Frade F
- Fraga GP
- Francisco Roxas M
- Franco H
- Francois P
- Francois-Coridon H
- Francone E
- Freitas AV
- Frey D
- Frisk B
- Fuentes-Rivera L
- Fujii F
- Furqan MM
- Gaafar S
- Gaarder T
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- Gadhvi V
- Gado A
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- Gaizauskas V
- Gala T
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- Galiqi G
- Galleano R
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- Galvez CP
- Gamal D
- Gamal E
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- Gamal S
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- Garaycochea O
- Garcia Bernardo C
- Garcia Florez LJ
- Garcia Septiem J
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- Guevara Torres S
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- Guglielmo V
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- Gunawan R
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- Halicioglu I
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- Hashad E
- Hasheminia A
- Hashim A
- Hashish A
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- Haslegrave A
- Hassaan A
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- Hassan ATA
- Hassan I
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- Hassanein AB
- Havemann I
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- Herrera Puma CM
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- Ibraheem HI
- Ibrahem AA
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- Ibrahim A
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- Ibrahim AM
- Ibrahim E
- Ibrahim EM
- Ibrahim I
- Ibrahim K
- Ibrahim M
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- Ibrahim Y
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- Iftekhar F
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- Ihediwa G
- Imoro O
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- Ingabire JCA
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- Ioannidis O
- Iordache F-M
- Iqbal FM
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- Ireland P
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- Korkolis D
- Kosai NR
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- Kotecha D
- Koto MZ
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- Koumpa F
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- Mohammad A
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- Montrimaite M
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- Sahel S
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- Sakr A
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- Salma U
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- Samalavicius NE
- Samaraweera DI
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- Samison LH
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- Wold TB
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- Yildirim R
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- Yoganathan P
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- Yong CO
- Yong GL
- Younis A
- Youssef D
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- Zaa'treh R
- Zachariades D-C
- Zadoroznas A
- Zahran D
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- Zakaria Y
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- Zapata Ponze De Leon M
- Zapata F
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- Zardab A
- Zegarra S
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- Zerihun AB
- Zeta Solis LA
- Zhang Z
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- Zilinskas J
- Zilinskas J
- Zilinskas J
- Zilinskas J
- Zilinskiene R
- Zilinskiene R
- Zimmermann EF
- Ziubryte G
- Zohair A
- Zorrilla CD
- Zuber M
- Zuber M
- Zuk G
- Zulkifli A
- Zumbuhl L
- Publication venue
- Publication date
- 15/10/2018
- Field of study
Background The World Health Organization (WHO) Surgical Safety Checklist has fostered safe practice for 10 years, yet its place in emergency surgery has not been assessed on a global scale. The aim of this study was to evaluate reported checklist use in emergency settings and examine the relationship with perioperative mortality in patients who had emergency laparotomy. Methods In two multinational cohort studies, adults undergoing emergency laparotomy were compared with those having elective gastrointestinal surgery. Relationships between reported checklist use and mortality were determined using multivariable logistic regression and bootstrapped simulation. Results Of 12 296 patients included from 76 countries, 4843 underwent emergency laparotomy. After adjusting for patient and disease factors, checklist use before emergency laparotomy was more common in countries with a high Human Development Index (HDI) (2455 of 2741, 89.6 per cent) compared with that in countries with a middle (753 of 1242, 60.6 per cent; odds ratio (OR) 0.17, 95 per cent c.i. 0.14 to 0.21, P <0001) or low (363 of 860, 422 per cent; OR 008, 007 to 010, P <0.001) HDI. Checklist use was less common in elective surgery than for emergency laparotomy in high-HDI countries (risk difference -94 (95 per cent c.i. -11.9 to -6.9) per cent; P <0001), but the relationship was reversed in low-HDI countries (+121 (+7.0 to +173) per cent; P <0001). In multivariable models, checklist use was associated with a lower 30-day perioperative mortality (OR 0.60, 0.50 to 073; P <0.001). The greatest absolute benefit was seen for emergency surgery in low- and middle-HDI countries. Conclusion Checklist use in emergency laparotomy was associated with a significantly lower perioperative mortality rate. Checklist use in low-HDI countries was half that in high-HDI countries.Peer reviewe
Analysis of shared heritability in common disorders of the brain
- Author
- Adams Hieab H.H.
- Air Tracy
- Al-Chalabi Ammar
- Alda Martin
- Alegret Montserrat
- Alfredsson Lars
- Amouyel Philippe
- Andlauer Till F.M.
- Andreassen Ole A.
- Anjorin Adebayo
- Anney Richard
- Anttila Verneri
- Arias Vasquez Alejandro
- Arking Dan
- Arnold Paul
- Arranz Maria Jesús
- Artto Ville
- Aschauer Harald
- Attia John
- Avbersek Andreja
- Bacchelli Elena
- Bailey Anthony
- Baker Jessica H.
- Bal Vanessa
- Banaschewski Tobias
- Barnes Lisa L.
- Barr Cathy L.
- Battaglia Agatino
- Battey Thomas
- Bau Claiton H.D.
- Bauer Michael
- Baum Larry
- Baune Bernhard T.
- Bayer Anthony
- Beach Thomas G.
- Becker Felicitas
- Bedoya-Berrio Gabriel
- Beekman Aartjan TF
- Beiser Alexa
- Belin Andrea C.
- Bergen Andrew W.
- Bergen Sarah E
- Berkovic Samuel
- Berr Claudine
- Betancur Catalina
- Bevan Steve
- Bienvenu O. Joseph
- Bis Joshua C
- Blackwood Douglas
- Boada Mercè
- Boland Anne
- Bolton Patrick
- Boncoraglio Giorgio
- Boomsma Dorret
- Boraska Perica Vesna
- Borck Guntram
- Bradfield Jonathan
- Bramon Elvira
- Bras Jose
- Breen Gerome
- Brentani Helena
- Buccola Nancy
- Buitelaar Jan K.
- Bulik Cynthia M.
- Bulik-Sullivan Brendan
- Buono Russell
- Buring Julie E.
- Burton Christie
- Børglum Anders D.
- Cahn Wiepke
- Cairns Murray
- Camarena Beatriz
- Cantor Rita
- Cappi Carolina
- Casas Miguel
- Catarino Claudia B.
- Cath Danielle
- Cavallini Maria
- Celestino-Soper Patrícia
- Chasman Daniel I.
- Chen Wei-Min
- Cheng Wei
- Chong Siow A.
- Chouraki Vincent
- Churchhouse Claire
- Cichon Sven
- Clementi Maurizio
- Cloninger Robert
- Cohen David
- Cohen-Woods Sarah
- Cook Edwin
- Cormand Bru
- Corvin Aiden
- Cossette Patrick
- Cotsapas Chris
- Craddock Nick
- Crespo-Facorro Benedicto
- Crosbie Jennifer
- Crowley James
- Cruceanu Cristiana
- Cruchaga Carlos
- Cuenca-Leon Ester
- Curtis David
- Cusi Daniele
- Czerski Piotr M.
- Dalsgaard Soeren
- Daly Mark
- Danner Unna N.
- Darrow Sabrina
- Davidson Michael
- Davis Oliver S. P.
- Dawson Geraldine
- de Geus Eco
- De Jager Philip L.
- De Jonghe Peter
- De Rubeis Silvia
- De-Luca Daniel Moreno-
- Degenhardt Franziska
- Deleuze Jean-François
- DeLisi Lynn
- Delorme Richard
- Demirci F. Yesim
- Dempfle Astrid
- Denys Damiaan
- Depienne Christel
- Depondt Chantal
- Derks Eske M.
- Dichgans Martin
- Dick Danielle M.
- Dietrich Andrea
- Dinan Timothy
- Dlugos Dennis
- Docampo Elisa
- Donohoe Gary
- Doyle Alysa E.
- Drapeau Elodie
- Duan Jubao
- Duncan Laramie
- Dunn Erin
- Duque Frederico
- Duron Emmanuelle
- Edenberg Howard J.
- Ehrlich Stefan
- Elia Josephine
- Eriksson Nicholas
- Escott-Price Valentina
- Espeseth Thomas
- Falcone Guido J.
- Faraone Stephen V.
- Farh Kai-How
- Farrer Lindsay A.
- Fernandez Thomas
- Ferrari Michel D.
- Ferraro Thomas N.
- Ferrier I. Nicol
- Figee Martijn
- Finucane Hilary K.
- Fischer Sascha B.
- Forstner Andreas J.
- Forzan Monica
- Fox Nick C.
- Franke Barbara
- Freilinger Tobias
- Freimer Nelson
- Freitag Christine
- French Jacqueline
- Fullerton Janice M.
- Furlotte Nicholas
- Gasser Thomas
- Gejman Pablo V.
- Gerber Gloria
- Gershon Elliot S.
- Geschwind Daniel H.
- Gibbs Raphael
- Goate Alison M.
- Goes Fernando S.
- Gonidakis Fragiskos
- Gordon Scott D.
- Gormley Padhraig
- Grabe Hans-Jorgen
- Grados Marco
- Gratacos Monica
- Green Andrew
- Greenberg Erica
- Grenier-Boley Benjamin
- Grevet Eugenio H.
- Grigoroiu-Serbanescu Maria
- Grove Jakob
- Guerreiro Rita
- Guzman-Parra José
- Göbel Hartmut
- Haan Lieuwe
- Haavik Jan
- Hakonarson Hakon
- Halmi Katherine A.
- Hampel Harald
- Hanna Gregory L.
- Hannequin Didier
- Hansen Thomas
- Harold Denise
- Hartmann Andreas
- Hauser Joanna
- Head Elizabeth
- Heinzen Erin L.
- Helder Sietske G.
- Henskens Frans
- Herms Stefan
- Herpertz-Dahlmann Beate
- Hervas Amaia
- Heutink Peter
- Hickie Ian
- Hirschtritt Matthew E.
- Hjalgrim Helle
- Hoekstra Pieter J.
- Hoffmann Per
- Holliday Elizabeth
- Holmans Peter
- Homuth Georg
- Hottenga Jouke-Jan
- Hougaard David
- Hrafnsdottir Maria
- Huang Alden
- Huang Hailiang
- Huang Jie
- Huckins Laura M.
- Hudson James I.
- Huentelman Matthew J.
- Hulette Christine M.
- Huyser Chaim
- Hyman Bradley T.
- Hämäläinen Eija
- Illmann Cornelia
- Jamain Stéphane
- Jamnadas-Khoda Jennifer
- Jansen Rick
- Jenike Michael
- Jicha Gregory A.
- Johansson Stefan
- Jones Ian R.
- Julià Antonio
- Kamatani Yoichiro
- Kamboh M. Ilyas
- Kaprio Jaakko
- Karachanak-Yankova Sena
- Karwautz Andreas
- Kaunisto Mari
- Kauwe John S.K.
- Kaye Jeffrey A.
- Kaye Walter
- Kendler Kenneth S.
- Keski-Rahkonen Anna
- Khrunin Andrey
- Klauck Sabine M.
- Klovins Janis
- Knowles James A.
- Koeleman Bobby
- Konkashbaev Anuar
- Kornhuber Johannes
- Kourkoulis Christina
- Kubisch Christian
- Kukull Walter A.
- Kuntsi Jonna
- Kunz Wolfram S.
- Kuperman Samuel
- Kurki Mitja I.
- Kurth Tobias
- Kučinskas Vaidutis
- Kälviäinen Reetta
- Langley Kate
- Lanzagorta Nuria
- Larson Eric B.
- Lawlor Brian
- Leber Markus
- Leboyer Marion
- Lee Chee Keong Jimmy
- Lee Phil H.
- Lehtimäki Terho
- Lerche Holger
- Lesch Klaus-Peter
- Letenneur Luc
- Leu Costin
- Leventhal Bennett
- Leverenz James B.
- Levey Allan I.
- Levitt Pat
- Lewis Cathryn M.
- Li Qingqin S.
- Lieberman Andrew P.
- Ligthart Lannie
- Limborska Svetlana
- Lindhout Dick
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- Loo Sandra K.
- Loughland Carmel
- Lowenstein Daniel
- Lundervold Astri J.
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- Lyon Gholson J.
- Lönnqvist Jouko
- Maaser Anna
- Macaya Alfons
- Macciardi Fabio
- MacIntyre Donald J.
- Madruga-Garrido Marcos
- Maestrini Elena
- Magalhaes Tiago
- Maher Brion
- Maj Mario
- Malaty Irene A.
- Malik Rainer
- Mane Shrikant
- Mannik Katrin
- Maras Athanasios
- Markus Hugh
- Marson Anthony
- Martin Nicholas G.
- Martinez Maria
- Mathews Carol A.
- Mattheisen Manuel
- Matthews Keith
- Mattingsdal Morten
- Mayoral Fermin
- McCormack Mark
- McDonald Colm
- McGough James J.
- McGrath Lauren
- McIntosh Andrew
- McLaughlin Nicole
- McQuillin Andrew
- Mead Simon
- Medland Sarah E.
- Mehta Divya
- Melle Ingrid
- Metspalu Andres
- Middeldorp Christel M.
- Miguel Eurípedes C.
- Mir Pablo
- Mitchell Braxton
- Mitchell James
- Mitchell Philip B.
- Mok Kin Y.
- Molloy Anne
- Molly Nikolas
- Monteleone Palmiero
- Montgomery Grant W.
- Morgan Kevin
- Morris Derek
- Morris Huw R.
- Muller-Myhsok Bertram
- Murphy Kieran C.
- Murray Robin
- Møller Rikke S.
- Mühleisen Thomas W.
- Nauck Matthias
- Neale Benjamin M.
- Nenadic Igor
- Nestadt Gerald
- Nestadt Paul S.
- Ng Ping-Wing
- Nicolini Humberto
- Nyholt Dale R.
- Nöthen Markus M.
- Oades Robert D.
- Oh Sang-Yun
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- Olesen Jes
- Oliver Karen
- Ophoff Roel
- Owen Michael J.
- O’Toole Julie K.
- Padyukov Leonid
- Pakstis Andrew
- Palmason Haukur
- Palotie Aarno
- Palta Priit
- Pankratz Vernon S.
- Pantelis Christos
- Papezova Hana
- Parr Jeremy
- Paschou Peristera
- Passmore Peter
- Pato Carlos
- Pato Michele
- Patsopoulos Nikolaos A.
- Penninx Brenda
- Pera Joana
- Pergadia Michele
- Petryshen Tracey
- Piacentini John
- Pinto Dalila
- Pittenger Christopher
- Plessen Kerstin
- Poon Wayne W.
- Porteous David
- Posthuma Danielle
- Potash James B.
- Pozo-Rosich Patricia
- Price Alkes
- Privitera Michael
- Proitsi Petra
- Pulit Sara
- Quested Digby
- Quinn Joseph F.
- Rabionet Raquel
- Radtke Rodney
- Raevuori Anu
- Raffeld Miriam
- Ramensky Vasily
- Ramos Eliana M.
- Ramos-Quiroga Josep Antoni
- Ran Caroline
- Ransmayr Gerhard
- Regan Regina
- Reichborn-Kjennerud Ted
- Reichenberg Abraham
- Reif Andreas
- Reinbold Céline S.
- Reitz Christiane
- Reus Victor
- Ribasés Marta
- Rice John
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- Richter Margaret A.
- Riddle Mark A.
- Riedel-Heller Steffi
- Riemenschneider Matthias
- Rietschel Marcella
- Ripatti Samuli
- Ripke Stephan
- Rivera Margarita
- Rivero Olga
- Robertson Mary M.
- Robinson Elise
- Roessner Veit
- Rogaeva Ekaterina
- Rogé Bernadette
- Romanos Marcel
- Rosand Jonathan
- Rossor Martin
- Rosário Maria
- Rothenberger Aribert
- Rothwell Peter
- Rotter Jerome I
- Rouleau Guy A.
- Roussos Panos
- Rubinsztein David C.
- Ruiz Agustin
- Ruppert Ann-Kathrin
- Russo Giancarlo
- Rybakowski Filip
- Ryten Mina
- Salomaa Veikko
- Samuels Jack F.
- Sander Thomas
- Sanders Alan R.
- Sandin Sven
- Sandor Cynthia
- Sandor Paul
- Santangelo Susan
- Saykin Andrew J.
- Schachar Russell
- Schachter Steven
- Schall Ulrich
- Schalling Martin
- Schankin Christoph
- Scharf Jeremiah
- Scheffer Ingrid
- Scherer Stephen W.
- Schneider Lon S.
- Schoch Susanne
- Schoevers Robert A.
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- Schosser Alexandra
- Schott Jonathan M.
- Schreiber Stefan
- Schulze Thomas G.
- Schumacher Johannes
- Schwab Sibylle G.
- Schürks Markus
- Scott Rodney
- Seshadri Sudha
- Sharma Manu
- Sharma Pankaj
- Silliman Scott
- Sim Kang
- Sinnamon Grant
- Sisodiya Sanjay M.
- Sklar Pamela
- Smit Johannes H.
- Smith Amanda G.
- Smith Philip
- Smoller Jordan W.
- So Hon-Cheong
- Sonnen Joshua A.
- Sperling Michael
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- Streit Fabian
- Striano Pasquale
- Strober Michael
- Strohmaier Jana
- Stroink Hans
- Stögmann Elisabeth
- Subramaniam Mythily
- Sudlow Cathie
- Sullivan Patrick
- Surges Rainer
- Szatkiewicz Jin Peng
- Sánchez-Mora Cristina
- Terwindt Gisela M.
- The Brainstorm Consortium
- Thijs Vincent
- Thomas G. Neil
- Thompson Robert C.
- Thornton Laura M.
- Toncheva Draga
- Tortorella Alfonso
- Trace Sara E.
- Tsetsos Fotis
- Tsolaki Magda
- Turecki Gustavo
- Turley Patrick
- Tziouvas Konstantinos
- Valencia-Duarte Ana
- Van Deerlin Vivianna M.
- van den Maagdenberg Arn M.J.M.
- van der Lee Sven J.
- van Elburg Annemarie A.
- Van Eldik Linda J.
- Van Nieuwerburgh Filip
- van Os Jim
- Vardarajan Badri N.
- Vepsäläinen Salli
- Vicente Astrid
- Viktorin Alexander
- Visscher Frank
- Vorstman Jacob
- Waddington John
- Wagner Gudrun
- Waldman Irwin
- Walters James
- Walters Raymond K.
- Wassink Thomas
- Weatherall Sarah
- Webb Bradley
- Webber Caleb
- Wedenoja Juho
- Wei Zhi
- Weiser Mark
- Weiss Lauren A.
- Wendland Jens R.
- Werge Thomas
- Whelan Christopher D.
- Wijsman Ellen
- William Rayner N.
- Williams Julie
- Williams Nigel
- Wilmot Beth
- Winsvold Bendik
- Witt Stephanie H.
- Wolanczyk Tomasz
- Wood Nicholas W.
- Worbe Yulia
- Wray Naomi R.
- Yilmaz Zeynep
- Yu Dongmei
- Zai Gwyneth
- Zandi Peter P.
- Zara Federico
- Zayats Tetyana
- Zimprich Fritz
- Zwart John-Anker
- Publication venue
- American Association for the Advancement of Science
- Publication date
- 01/01/2018
- Field of study
ience, this issue p. eaap8757 Structured Abstract INTRODUCTION Brain disorders may exhibit shared symptoms and substantial epidemiological comorbidity, inciting debate about their etiologic overlap. However, detailed study of phenotypes with different ages of onset, severity, and presentation poses a considerable challenge. Recently developed heritability methods allow us to accurately measure correlation of genome-wide common variant risk between two phenotypes from pools of different individuals and assess how connected they, or at least their genetic risks, are on the genomic level. We used genome-wide association data for 265,218 patients and 784,643 control participants, as well as 17 phenotypes from a total of 1,191,588 individuals, to quantify the degree of overlap for genetic risk factors of 25 common brain disorders. RATIONALE Over the past century, the classification of brain disorders has evolved to reflect the medical and scientific communities' assessments of the presumed root causes of clinical phenomena such as behavioral change, loss of motor function, or alterations of consciousness. Directly observable phenomena (such as the presence of emboli, protein tangles, or unusual electrical activity patterns) generally define and separate neurological disorders from psychiatric disorders. Understanding the genetic underpinnings and categorical distinctions for brain disorders and related phenotypes may inform the search for their biological mechanisms. RESULTS Common variant risk for psychiatric disorders was shown to correlate significantly, especially among attention deficit hyperactivity disorder (ADHD), bipolar disorder, major depressive disorder (MDD), and schizophrenia. By contrast, neurological disorders appear more distinct from one another and from the psychiatric disorders, except for migraine, which was significantly correlated to ADHD, MDD, and Tourette syndrome. We demonstrate that, in the general population, the personality trait neuroticism is significantly correlated with almost every psychiatric disorder and migraine. We also identify significant genetic sharing between disorders and early life cognitive measures (e.g., years of education and college attainment) in the general population, demonstrating positive correlation with several psychiatric disorders (e.g., anorexia nervosa and bipolar disorder) and negative correlation with several neurological phenotypes (e.g., Alzheimer's disease and ischemic stroke), even though the latter are considered to result from specific processes that occur later in life. Extensive simulations were also performed to inform how statistical power, diagnostic misclassification, and phenotypic heterogeneity influence genetic correlations. CONCLUSION The high degree of genetic correlation among many of the psychiatric disorders adds further evidence that their current clinical boundaries do not reflect distinct underlying pathogenic processes, at least on the genetic level. This suggests a deeply interconnected nature for psychiatric disorders, in contrast to neurological disorders, and underscores the need to refine psychiatric diagnostics. Genetically informed analyses may provide important "scaffolding" to support such restructuring of psychiatric nosology, which likely requires incorporating many levels of information. By contrast, we find limited evidence for widespread common genetic risk sharing among neurological disorders or across neurological and psychiatric disorders. We show that both psychiatric and neurological disorders have robust correlations with cognitive and personality measures. Further study is needed to evaluate whether overlapping genetic contributions to psychiatric pathology may influence treatment choices. Ultimately, such developments may pave the way toward reduced heterogeneity and improved diagnosis and treatment of psychiatric disorders
Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
- Author
- Abbafati Cristiana
- Abbas Kaja M.
- Abbasi Mohammad
- Abbasi-Kangevari Mohsen
- Abbasifard Mitra
- Abbastabar Hedayat
- Abd El Razek Hassan Magdy
- Abd El Razek Muhammed Magdy
- Abd-Allah Foad
- Abdelalim Ahmed
- Abdollahi Mohammad
- Abdollahpour Ibrahim
- Abdulkader Rizwan Suliankatchi
- Abdullah Kanaan Hamagharib
- Abedi Aidin
- Abedi Parisa
- Abegaz Kedir Hussein
- Abolhassani Hassan
- Abosetugn Akine Eshete
- Aboyans Victor
- Abrams Elissa M.
- Abreu Lucas Guimaraes
- Abrigo Michael R. M.
- Abu Haimed Abdulaziz Khalid
- Abu-Gharbieh Eman
- Abu-Raddad Laith Jamal
- Abualhasan Ahmed
- Abushouk Abdelrahman I.
- Acebedo Alyssa
- Ackerman Ilana N.
- Adabi Maryam
- Adair Tim
- Adamu Abdu A.
- Adebayo Oladimeji M.
- Adedeji Isaac Akinkunmi
- Adekanmbi Victor
- Adelson Jaimie D.
- Adeoye Abiodun Moshood
- Adetokunboh Olatunji O.
- Adham Davoud
- Advani Shailesh M.
- Afarideh Mohsen
- Afshari Mahdi
- Afshin Ashkan
- Agardh Emilie E.
- Agarwal Gina
- Agasthi Pradyumna
- Agesa Kareha M.
- Aghaali Mohammad
- Aghamir Seyed Mohammad Kazem
- Agrawal Anurag
- Ahmad Tauseef
- Ahmadi Alireza
- Ahmadi Keivan
- Ahmadi Mehdi
- Ahmadieh Hamid
- Ahmadpour Ehsan
- Ahmed Muktar Beshir
- Aji Budi
- Akalu Temesgen Yihunie
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- Johnson Catherine Owens
- Johnson Sarah Charlotte
- Jonas Jost B.
- Joo Tamas
- Joshi Ankur
- Joukar Farahnaz
- Jozwiak Jacek Jerzy
- Jurisson Mikk
- Kabir Ali
- Kabir Zubair
- Kafil Hossein Samadi
- Kalan Mohammad Ebrahimi
- Kalani Hamed
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- Kalhor Rohollah
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- Kamath Aruna M.
- Kamiab Zahra
- Kanchan Tanuj
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- Karanikolos Marina
- Karch Andre
- Karim Mohd Anisul
- Karimi Salah Eddin
- Karimi Seyed Asaad
- Karimi Seyed M.
- Karyani Ali Kazemi
- Kasa Ayele Semachew
- Kassa Getachew Mullu
- Kassebaum Nicholas J.
- Katikireddi Srinivasa Vittal
- Kawakami Norito
- Kayode Gbenga A.
- Keddie Suzanne H.
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- Keller Cathleen
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- Kendrick Parkes J.
- Kereselidze Maia
- Khader Yousef Saleh
- Khafaie Morteza Abdullatif
- Khalid Nauman
- Khammarnia Mohammad
- Khan Ejaz Ahmad
- Khan Gulfaraz
- Khan Maseer
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- Khang Young-Ho
- Khatab Khaled
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- Khatib Mahalaqua Nazli
- Khayamzadeh Maryam
- Khazaei Salman
- Khazaie Habibolah
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- Khoja Abdullah T.
- Khubchandani Jagdish
- Khundkar Roba
- Kianipour Neda
- Kieling Christian
- Kim Cho-Il
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- Kim Young-Eun
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- Moghadam Telma Zahirian
- Moghadaszadeh Masoud
- Moghaddam Sahar Saeedi
- Mohajer Bahram
- Mohamad Osama
- Mohamadi Efat
- Mohammad Dara K.
- Mohammad Yousef
- Mohammadbeigi Abolfazl
- Mohammadian-Hafshejani Abdollah
- Mohammadifard Noushin
- Mohammadpourhodki Reza
- Mohammed Ammas Siraj
- Mohammed Hussen
- Mohammed Jemal Abdu
- Mohammed Shafiu
- Mohebi Farnam
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- Molokhia Mariam
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- Moradi Ghobad
- Moradi Masoud
- Moradi-Joo Mohammad
- Moradi-Lakeh Maziar
- Moradzadeh Rahmatollah
- Moraga Paula
- Morales Linda
- Morawska Lidia
- Morgado-da-Costa Joana
- Morrison Shane Douglas
- Mosapour Abbas
- Mosser Jonathan F.
- Motlagh Soraya Nouraei
- Mouodi Simin
- Mousavi Seyyed Meysam
- Mueller Ulrich Otto
- Mukhopadhyay Satinath
- Mullany Erin C.
- Mumford John Everett
- Munro Sandra B.
- Muriithi Moses K.
- Murray Christopher J. L.
- Musa Kamarul Imran
- Mustafa Ghulam
- Muthupandian Saravanan
- Nabavizadeh Behnam
- Nabhan Ashraf F.
- Naderi Mehdi
- Nagaraja Sharath Burugina
- Nagarajan Ahamarshan Jayaraman
- Nagel Gabriele
- Naghavi Mohsen
- Naghshtabrizi Behshad
- Naik Gurudatta
- Naimzada Mukhammad David
- Nair Sanjeev
- Najafi Farid
- Naldi Luigi
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- Nansseu Jobert Richie
- Nasab Entezar Mehrabi
- Naserbakht Morteza
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- Nazari Javad
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- Ndwandwe Duduzile Edith
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- Negoi Ruxandra Irina
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- Ngari Kiirithio N.
- Nguefack-Tsague Georges
- Ngunjiri Josephine W.
- Nguyen Cuong Tat
- Nguyen Diep Ngoc
- Nguyen Huong Lan Thi
- Nguyen Jason
- Nguyen Michele
- Nguyen Ming
- Nguyen Trang Huyen
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- Nigatu Dabere
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- Nikbakhsh Rajan
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- Nnaji Chukwudi A.
- Nomura Shuhei
- Norheim Ole F.
- Norrving Bo
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- Nowak Christoph
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- Ogbo Felix Akpojene
- Oghenetega Onome Bright
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- Okunga Emmanuel Wandera
- Oladnabi Morteza
- Olagunju Andrew T.
- Olusanya Bolajoko Olubukunola
- Olusanya Jacob Olusegun
- Oluwasanu Mojisola Morenike
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- Otstavnov Nikita
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- Overland Simon
- Owolabi Mayowa O.
- Padubidri Jagadish Rao
- Pakhale Smita
- Pakhare Abhijit P.
- Pakshir Keyvan
- Palladino Raffaele
- Pana Adrian
- Panda-Jonas Songhomitra
- Pandey Anamika
- Pangaribuan Helena Ullyartha
- Park Eun-Kee
- Park James
- Parmar Priya G. Kumari
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- Pasovic Maja
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- Patel Jenil R.
- Patel Sangram Kishor
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- Pathak Ashish
- Pathak Mona
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- Patton George C.
- Paudel Deepak
- Paudel Sagun
- Paulson Katherine R.
- Pease Spencer A.
- Peden Amy E.
- Pennini Alyssa
- Pepito Veincent Christian Filipino
- Peprah Emmanuel K.
- Pereira Alexandre
- Pereira David M.
- Pereira Jeevan
- Perico Norberto
- Pescarini Julia Moreira
- Pesudovs Konrad
- Pham Hai Quang
- Phillips Michael R.
- Piccinelli Cristiano
- Pierce Maxwell
- Pigott David M.
- Pilgrim Thomas
- Pilz Tessa M.
- Pinheiro Marina
- Piradov Michael A.
- Pirsaheb Meghdad
- Pishgar Farhad
- Plana-Ripoll Oleguer
- Plass Dietrich
- Pletcher Martin
- Pokhrel Khem Narayan
- Polibin Roman V.
- Polinder Suzanne
- Polkinghorne Kevan R.
- Pond Constance Dimity
- Postma Maarten J.
- Pottoo Faheem Hyder
- Pourjafar Hadi
- Pourmalek Farshad
- Pourshams Akram
- Poznanska Anna
- Prada Sergio I.
- Prakash Sanjay
- Prakash V.
- Prasad Narayan
- Preotescu Liliana
- Pribadi Dimas Ria Angga
- Pupillo Elisabetta
- Quazi Syed Zahiruddin
- Quintanilla Beatriz Paulina Ayala
- Rabiee Mohammad
- Rabiee Navid
- Radfar Amir
- Rafiee Ata
- Rafiei Alireza
- Raggi Alberto
- Rahim Fakher
- Rahimi-Movaghar Afarin
- Rahman Mohammad Hifz Ur
- Rahman Muhammad Aziz
- Rajabpour-Sanati Ali
- Rajati Fatemeh
- Rakovac Ivo
- Ram Pradhum
- Ramezanzadeh Kiana
- Rana Saleem Muhammad
- Ranabhat Chhabi Lal
- Ranta Annemarei
- Rao Puja C.
- Rao Sowmya J.
- Rasella Davide
- Rashedi Vahid
- Rastogi Prateek
- Rath Goura Kishor
- Rathi Priya
- Rawaf David Laith
- Rawaf Salman
- Rawal Lal
- Rawassizadeh Reza
- Rawat Ramu
- Razo Christian
- Regassa Lemma Demissie
- Reiner Robert C., Jr.
- Reinig Nickolas
- Reitsma Marissa Bettay
- Remuzzi Giuseppe
- Renjith Vishnu
- Renzaho Andre M. N.
- Resnikoff Serge
- Rezaei Negar
- Rezaei Nima
- Rezai Mohammad Sadegh
- Rezapour Aziz
- Rhinehart Phoebe-Anne
- Riahi Seyed Mohammad
- Ribeiro Antonio Luiz P.
- Ribeiro Daniel Cury
- Ribeiro Daniela
- Rickard Jennifer
- Rincon Julio Cesar Campuzano
- Rivera Juan A.
- Robalik Toshana
- Roberts Nicholas L. S.
- Roberts Shaun
- Robinson Stephen R.
- Rodriguez-Ramirez Sonia
- Roever Leonardo
- Rolfe Sam
- Romoli Michele
- Ronfani Luca
- Room Robin
- Roshandel Gholamreza
- Rostamian Morteza
- Roth Gregory A.
- Rothenbacher Dietrich
- Rubagotti Enrico
- Rumisha Susan Fred
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- Saadatagah Seyedmohammad
- Sabour Siamak
- Sachdev Perminder S.
- Saddik Basema
- Sadeghi Ehsan
- Sadeghi Masoumeh
- Saeedi Reza
- Saeidi Shahram
- Safari Yahya
- Safi Sare
- Safiri Saeid
- Sagar Rajesh
- Sahebkar Amirhossein
- Sahraian Mohammad Ali
- Sajadi S. Mohammad
- Salahshoor Mohammad Reza
- Salam Nasir
- Salama Joseph S.
- Salamati Payman
- Salem Hosni
- Salem Marwa R.
- Salimi Yahya
- Salimzadeh Hamideh
- Salman Omar Mukhtar
- Salomon Joshua A.
- Salz Inbal
- Samad Zainab
- Sambala Evanson Zondani
- Samy Abdallah M.
- Sanabria Juan
- Sanchez-Pimienta Tania G.
- Santomauro Damian Francesco
- Santos Itamar S.
- Santos Joao Vasco
- Santric-Milicevic Milena M.
- Saraswathy Sivan Yegnanarayana Iyer
- Sarmiento-Suarez Rodrigo
- Sarrafzadegan Nizal
- Sartorius Benn
- Sarveazad Arash
- Sathian Brijesh
- Sathish Thirunavukkarasu
- Sattin Davide
- Savic Miloje
- Sawyer Susan M.
- Saxena Deepak
- Saxena Sonia
- Saylan Mete
- Sbarra Alyssa N.
- Schaeffer Lauren E.
- Schiavolin Silvia
- Schlaich Markus P.
- Schmidt Maria Ines
- Schutte Aletta Elisabeth
- Schwebel David C.
- Schwendicke Falk
- Section Mahesh P. A.
- Seedat Soraya
- Sekerija Mario
- Senbeta Anbissa Muleta
- Senthilkumaran Subramanian
- Sepanlou Sadaf G.
- Serdar Berrin
- Serre Marc L.
- Servan-Mori Edson
- Sha Feng
- Shabani Mahsima
- Shackelford Katya Anne
- Shadid Jamileh
- Shafaat Omid
- Shahabi Saeed
- Shahbaz Mohammad
- Shaheen Amira A.
- Shaikh Masood Ali
- Shaji K. S.
- Shalash Ali S.
- Shams-Beyranvand Mehran
- Shamsi MohammadBagher
- Shamsizadeh Morteza
- Shannawaz Mohammed
- Sharafi Kiomars
- Sharafi Zeinab
- Sharan Subodh
- Sharara Fablina
- Sharifi Hamid
- Sharma Rajesh
- Shaw David H.
- Sheena Brittney S.
- Sheikh Aziz
- Sheikhtaheri Abbas
- Shetty B. Suresh Kumar
- Shetty Ranjitha S.
- Shibuya Kenji
- Shield Kevin David
- Shiferaw Wondimeneh Shibabaw
- Shigematsu Mika
- Shin Min-Jeong
- Shiri Rahman
- Shirkoohi Reza
- Shivakumar K. M.
- Shrime Mark G.
- Shuval Kerem
- Siabani Soraya
- Sierpinski Radoslaw
- Sigfusdottir Inga Dora
- Sigurvinsdottir Rannveig
- Silva Diego Augusto Santos
- Silva Joao Pedro
- Simonetti Biagio
- Simpson Kyle E.
- Singh Ambrish
- Singh Jasvinder A.
- Singh Pushpendra
- Sinha Dhirendra Narain
- Skiadaresi Eirini
- Skou Soren T.
- Skryabin Valentin Yurievich
- Sliwa Karen
- Smith Amanda
- Smith Emma U. R.
- Sobngwi Eugene
- Soheili Amin
- Sokhan Anton
- Soltani Shahin
- Somefun Oluwaseyi Dolapo
- Soofi Moslem
- Sorensen Reed J. D.
- Soriano Joan B.
- Sorrie Muluken Bekele
- Soshnikov Sergey
- Soyiri Ireneous N.
- Spencer Cory N.
- Spotin Adel
- Spurlock Emma Elizabeth
- Sreeramareddy Chandrashekhar T.
- Srinivasan Vinay
- Sripada Kam
- Stanaway Jeffrey D.
- Stark Benjamin A.
- Steel Nicholas
- Stefan Simona Catalina
- Stein Caroline
- Stein Dan J.
- Steiner Caitlyn
- Steiner Timothy J.
- Steuben Krista M.
- Stockfelt Leo
- Stokes Mark A.
- Stovner Lars Jacob
- Straif Kurt
- Stranges Saverio
- Stubbs Jacob L.
- Suchdev Parminder S.
- Sudaryanto Agus
- Sufiyan Mu'awiyyah Babale
- Suleria Hafiz Ansar Rasul
- Sulo Gerhard
- Sultan Iyad
- Swope Carolyn B.
- Sykes Bryan L.
- Sylte Dillon O.
- Szocska Miklos
- Szumowski Lukasz
- Tabares-Seisdedos Rafael
- Tabb Karen M.
- Tabuchi Takahiro
- Tadakamadla Santosh Kumar
- Taddele Biruk Wogayehu
- Tadesse Degena Bahrey
- Taherkhani Amir
- Tahir Zarfishan
- Tajdini Masih
- Takahashi Ken
- Takala Jukka S.
- Tamiru Animut Tagele
- Tang Muming
- Tanser Frank C.
- Tareque Md Ismail
- Tarigan Ingan Ukur
- Taveira Nuno
- Taylor Heather Jean
- Teagle Whitney L.
- Teame Hirut
- Tediosi Fabrizio
- Tefera Yonas Getaye
- Tehrani-Banihashemi Arash
- Teklehaimanot Berhane Fseha
- Tela Freweini Gebrearegay
- Temsah Mohamad-Hani
- Terrason Sonyah
- Tesema Getayeneh Antehunegn
- Tessema Zemenu Tadesse
- Thakur Bhaskar
- Thankappan Kavumpurathu Raman
- Thapar Rekha
- Thomas Nihal
- Thomson Azalea M.
- Thrift Amanda G.
- Thurston George D.
- Titova Mariya Vladimirovna
- Tlou Boikhutso
- Tohidinik Hamid Reza
- Tonelli Marcello
- Topor-Madry Roman
- Topouzis Fotis
- Toroudi Hamidreza Pazoki
- Torre Anna E.
- Touvier Mathilde
- Tovani-Palone Marcos Roberto
- Traini Eugenio
- Tran Bach Xuan
- Travillian Ravensara
- Trias-Llimos Sergi
- Troeger Christopher E.
- Truelsen Thomas Clement
- Tsai Alexander C.
- Tsatsakis Aristidis
- Tyrovolas Stefanos
- Uddin Riaz
- Ullah Irfan
- Ullah Saif
- Umeokonkwo Chukwuma David
- Undurraga Eduardo A.
- Unnikrishnan Bhaskaran
- Upadhyay Era
- Uthman Olalekan A.
- Vacante Marco
- Vaicekonyte Regina
- Vakilian Alireza
- Valdez Pascual R.
- Valli Alessandro
- Van Donkelaar Aaron
- Vardavas Constantine
- Varughese Santosh
- Vasankari Tommi Juhani
- Vasconcelos Ana Maria Nogales
- Vasseghian Yasser
- Veisani Yousef
- Velasquez Ilais Moreno
- Venketasubramanian Narayanaswamy
- Vidale Simone
- Violante Francesco S.
- Vlassov Vasily
- Vollset Stein Emil
- Vongpradith Avina
- Vos Theo
- Vu Giang Thu
- Vujcic Isidora S.
- Vukovic Ana
- Vukovic Rade
- Waheed Yasir
- Wallin Mitchell Taylor
- Walters Magdalene K.
- Wamai Richard G.
- Wang Fang
- Wang Haidong
- Wang Hongbo
- Wang Jiayu
- Wang Yafeng
- Wang Yanzhong
- Wang Yuan-Pang
- Ward Joseph L.
- Watson Alexandrea
- Watson Stefanie
- Wei Jingkai
- Wei Melissa Y. Wei
- Weintraub Robert G.
- Weiss Daniel J.
- Weiss Jordan
- Welay Fissaha Tekulu
- Weldesamuel Girmay Teklay
- Werdecker Andrea
- West J. Jason
- Westerman Ronny
- Whisnant Joanna L.
- Whiteford Harvey A.
- Wiangkham Taweewat
- Wickramasinghe Nuwan Darshana
- Wiens Kirsten E.
- Wijeratne Tissa
- Wilner Lauren B.
- Wilson Shadrach
- Wiysonge Charles Shey
- Wojtyniak Bogdan
- Woldu Gebremariam
- Wolfe Charles D. A.
- Wondmeneh Temesgen Gebeyehu
- Wondmieneh Adam Belay
- Wool Eve E.
- Wozniak Sarah S.
- Wu Ai-Min
- Wu Chenkai
- Wu Junjie
- Wunrow Han Yong
- Xie Yang
- Xu Gelin
- Xu Rixing
- Yadgir Simon
- Yamada Tomohide
- Yamagishi Kazumasa
- Yaminfirooz Mousa
- Yano Yuichiro
- Yaya Sanni
- Yazdi-Feyzabadi Vahid
- Yearwood Jamal A.
- Yeheyis Tomas Y.
- Yeshitila Yordanos Gizachew
- Yilgwan Christopher Sabo
- Yilma Mekdes Tigistu
- Yip Paul
- Yonemoto Naohiro
- Yoon Seok-Jun
- York Hunter W.
- Younis Mustafa Z.
- Younker Theodore Patrick
- Yousefi Bahman
- Yousefi Zabihollah
- Yousefifard Mahmoud
- Yousefinezhadi Taraneh
- Yousuf Abdilahi Yousuf
- Yu Chuanhua
- Yu Yong
- Yuan Chun-Wei
- Yuce Deniz
- Yusefzadeh Hasan
- Zadey Siddhesh
- Zahabi Saleh Salehi
- Zaidi Syed Saoud
- Zaki Leila
- Zaki Maysaa El Sayed
- Zakzuk Josefina
- Zamani Mohammad
- Zamanian Maryam
- Zandian Hamed
- Zangeneh Alireza
- Zarafshan Hadi
- Zastrozhin Mikhail Sergeevich
- Zewdie Kaleab Alemayehu
- Zhang Jianrong
- Zhang Yunquan
- Zhang Zhi-Jiang
- Zhao Jeff T.
- Zhao Xiu-Ju George
- Zhao Yingxi
- Zheleva Bistra
- Zheng Peng
- Zhou Maigeng
- Zhu Cong
- Ziapour Arash
- Zimsen Stephanie R. M.
- Zlavog Bianca S.
- Zodpey Sanjay
- Publication venue
- Publication date
- 01/01/2020
- Field of study
Background: In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic scientific assessment of published, publicly available, and contributed data on incidence, prevalence, and mortality for a mutually exclusive and collectively exhaustive list of diseases and injuries. Methods: GBD estimates incidence, prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) due to 369 diseases and injuries, for two sexes, and for 204 countries and territories. Input data were extracted from censuses, household surveys, civil registration and vital statistics, disease registries, health service use, air pollution monitors, satellite imaging, disease notifications, and other sources. Cause-specific death rates and cause fractions were calculated using the Cause of Death Ensemble model and spatiotemporal Gaussian process regression. Cause-specific deaths were adjusted to match the total all-cause deaths calculated as part of the GBD population, fertility, and mortality estimates. Deaths were multiplied by standard life expectancy at each age to calculate YLLs. A Bayesian meta-regression modelling tool, DisMod-MR 2.1, was used to ensure consistency between incidence, prevalence, remission, excess mortality, and cause-specific mortality for most causes. Prevalence estimates were multiplied by disability weights for mutually exclusive sequelae of diseases and injuries to calculate YLDs. We considered results in the context of the Socio-demographic Index (SDI), a composite indicator of income per capita, years of schooling, and fertility rate in females younger than 25 years. Uncertainty intervals (UIs) were generated for every metric using the 25th and 975th ordered 1000 draw values of the posterior distribution. Findings: Global health has steadily improved over the past 30 years as measured by age-standardised DALY rates. After taking into account population growth and ageing, the absolute number of DALYs has remained stable. Since 2010, the pace of decline in global age-standardised DALY rates has accelerated in age groups younger than 50 years compared with the 1990–2010 time period, with the greatest annualised rate of decline occurring in the 0–9-year age group. Six infectious diseases were among the top ten causes of DALYs in children younger than 10 years in 2019: lower respiratory infections (ranked second), diarrhoeal diseases (third), malaria (fifth), meningitis (sixth), whooping cough (ninth), and sexually transmitted infections (which, in this age group, is fully accounted for by congenital syphilis; ranked tenth). In adolescents aged 10–24 years, three injury causes were among the top causes of DALYs: road injuries (ranked first), self-harm (third), and interpersonal violence (fifth). Five of the causes that were in the top ten for ages 10–24 years were also in the top ten in the 25–49-year age group: road injuries (ranked first), HIV/AIDS (second), low back pain (fourth), headache disorders (fifth), and depressive disorders (sixth). In 2019, ischaemic heart disease and stroke were the top-ranked causes of DALYs in both the 50–74-year and 75-years-and-older age groups. Since 1990, there has been a marked shift towards a greater proportion of burden due to YLDs from non-communicable diseases and injuries. In 2019, there were 11 countries where non-communicable disease and injury YLDs constituted more than half of all disease burden. Decreases in age-standardised DALY rates have accelerated over the past decade in countries at the lower end of the SDI range, while improvements have started to stagnate or even reverse in countries with higher SDI. Interpretation: As disability becomes an increasingly large component of disease burden and a larger component of health expenditure, greater research and developm nt investment is needed to identify new, more effective intervention strategies. With a rapidly ageing global population, the demands on health services to deal with disabling outcomes, which increase with age, will require policy makers to anticipate these changes. The mix of universal and more geographically specific influences on health reinforces the need for regular reporting on population health in detail and by underlying cause to help decision makers to identify success stories of disease control to emulate, as well as opportunities to improve. Funding: Bill & Melinda Gates Foundation. © 2020 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licens
Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study
- Author
- Aahlin Eirik Kjus
- Aamer Ahmed
- Aaniana Kenneth
- Ababneh Ali
- Abaliksta Tomas
- Abantanga Francis
- Abbas Athar
- Abbasy Jibran
- Abbo Olivier
- Abbott Tom
- Abbouch Meryem
- Abd El-Latif Nadia Khalid
- Abd Elkhalek Esraa
- Abd-Elmawla Manar
- Abdallah Emad
- Abdel-Aty Abdulrahman
- Abdel-Hameed Noran
- Abdel-Kader Sara Mahmoud
- Abdelaal Abdelaziz
- Abdelaty Mohamed
- Abdelazeam Anan Rady
- Abdelazim Galaleldin
- Abdelaziz Mohamed A
- Abdelbadeai Kholoud
- Abdelfatah Afnan
- Abdelhady Samar
- Abdelhamed Rasha
- Abdelhamid Amina
- Abdelhaq Aram
- Abdelkader Mostafa
- Abdelkader Omar
- Abdelkhalek Mohamed
- Abdelmageed Eman
- Abdelmotaleb Ibrahem
- Abdelraouf Ahmed Mahmoud
- Abdelrouf Doaa Maher
- Abdelshakour Mahmoud
- Abdrabou Abdulshafi Khaled
- Abdul-Latif Saiba
- Abdulaziz Hager
- Abdulaziz Mustafa
- Abdulbagi Omar
- Abdulhakeem Eman Mahmoud
- Abdullah Mohamed Abozed
- Abdullah Nik Azim Nik
- Abdullah Noha
- Abdullahi Lawal
- Abdurrazzaaq Abdussemiu
- Abem Owusu Emmanuel
- Abiola Olajide
- Aboelella Majed
- Aboelmagd Omnia
- Aboelsoud Moustafa R
- Aboul-Naga Mariam Saad
- Abouzaid Arwa
- Abu Qumbos Amjad
- Abu-toyour Maram
- Abubakr Marwan
- Abuowda Yousef
- Abuqwaider Eman
- Abusalem Lana
- Abushamleh Soha
- Ackom Eric
- Acquah Emmanuel
- Adam Ali
- Adam Nourhan
- Adamu Ahmed
- Adawi Ihdaa
- Adawi Mohammad
- Adebanjo Ademola
- Adebola Oluwaseyi
- Adedeji Adesina
- Adel Badr Eldin
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- Adelshone Abdelrahman
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- Ahmed Asdaq
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- Walls Luke
- Walsh Michael
- Waqar Muhammad
- Warren Oliver
- Waterman Ade
- Werder Gabriela
- Whitaker John
- White Rebecca
- Whitehurst Katharine
- Wiborg Joachim
- Widiastini T Ariani
- Widmer Lukas Werner
- Wijayarathna LS
- Williams Omolara
- Wilson Ling
- Wilson Michael
- Wilson Michael
- Wimalge PMSN
- Wogensen Fredrik
- Wolf Bernhard
- Wondoh Paul
- Wondoh Paul
- Wong Chui Yee
- Wong Francisca
- Wong Hong Yee
- Wood Greta
- Worku Mengistu
- Worku Tewodros
- Wright Naomi
- Yahaya Muhammad Taqiyuddin
- Yakubu Musah
- Yam Sir Young
- Yang James
- Yap Suhhuey
- Yau Jih Dar
- Ye Joselyn
- Yeang Li Jing
- Yeung Man Hon Andrew
- Yifieyeh Abiboye
- Yildirim Reyyan
- Yip Chingwan
- Ymeri Shpetim
- Yoganathan Pigeneswaren
- Yolcu Sinem
- Yong Guo Liang
- Younis Abobaker
- Youssef Mohamed
- Yuksek Mahmut Arif
- Yusufali Taha
- Zaa'treh Rula
- Zadoroznas Antanas
- Zahran Diaaaldin
- Zakaria Esraay
- Zakaria Mahmoud
- Zakaria Yehia
- Zaki Ahmed
- Zammit Stefan
- Zampitis Nikolaos
- Zani Augusto
- Zani Augusto
- Zanini Nicola
- Zapata Felipe
- Zarb Ciskje
- Zeta Solis Ludwing Alexander
- Zielinski Martin
- Zilinskas Justas
- Zilinskas Justas
- Zilinskas Justas
- Zilinskiene Reda
- Ziubryte Greta
- Zohair Ahmed
- Zuber Markus
- Zuk Grzegorz
- Zulkifli Athirah
- Zumbuhl Lucius
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2018
- Field of study
Background: Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global health priority is not fully understood. We quantified the burden of SSI after gastrointestinal surgery in countries in all parts of the world.
Methods: This international, prospective, multicentre cohort study included consecutive patients undergoing elective or emergency gastrointestinal resection within 2-week time periods at any health-care facility in any country. Countries with participating centres were stratified into high-income, middle-income, and low-income groups according to the UN's Human Development Index (HDI). Data variables from the GlobalSurg 1 study and other studies that have been found to affect the likelihood of SSI were entered into risk adjustment models. The primary outcome measure was the 30-day SSI incidence (defined by US Centers for Disease Control and Prevention criteria for superficial and deep incisional SSI). Relationships with explanatory variables were examined using Bayesian multilevel logistic regression models. This trial is registered with ClinicalTrials.gov, number NCT02662231.
Findings: Between Jan 4, 2016, and July 31, 2016, 13 265 records were submitted for analysis. 12 539 patients from 343 hospitals in 66 countries were included. 7339 (58·5%) patient were from high-HDI countries (193 hospitals in 30 countries), 3918 (31·2%) patients were from middle-HDI countries (82 hospitals in 18 countries), and 1282 (10·2%) patients were from low-HDI countries (68 hospitals in 18 countries). In total, 1538 (12·3%) patients had SSI within 30 days of surgery. The incidence of SSI varied between countries with high (691 [9·4%] of 7339 patients), middle (549 [14·0%] of 3918 patients), and low (298 [23·2%] of 1282) HDI (p < 0·001). The highest SSI incidence in each HDI group was after dirty surgery (102 [17·8%] of 574 patients in high-HDI countries; 74 [31·4%] of 236 patients in middle-HDI countries; 72 [39·8%] of 181 patients in low-HDI countries). Following risk factor adjustment, patients in low-HDI countries were at greatest risk of SSI (adjusted odds ratio 1·60, 95% credible interval 1·05–2·37; p=0·030). 132 (21·6%) of 610 patients with an SSI and a microbiology culture result had an infection that was resistant to the prophylactic antibiotic used. Resistant infections were detected in 49 (16·6%) of 295 patients in high-HDI countries, in 37 (19·8%) of 187 patients in middle-HDI countries, and in 46 (35·9%) of 128 patients in low-HDI countries (p < 0·001).
Interpretation: Countries with a low HDI carry a disproportionately greater burden of SSI than countries with a middle or high HDI and might have higher rates of antibiotic resistance. In view of WHO recommendations on SSI prevention that highlight the absence of high-quality interventional research, urgent, pragmatic, randomised trials based in LMICs are needed to assess measures aiming to reduce this preventable complication
Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes
- Author
- Adolfsson Rolf
- Agartz Ingrid
- Agerbo Esben
- Akil Huda
- Albani Diego
- Albus Margot
- Alda Martin
- Alexander Madeline
- Alliey-Rodriguez Ney
- Als Thomas D
- Amin Farooq
- Andreassen Ole A
- Anjorin Adebayo
- Arranz Maria J
- Awasthi Swapnil
- Bacanu Silviu A
- Badner Judith A
- Baekvad-Hansen Marie
- Bakker Steven
- Band Gavin
- Barchas Jack D
- Barroso Ines
- Bass Nicholas
- Bauer Michael
- Baune Bernhard T
- Begemann Martin
- Bellenguez Celine
- Bellivier Frank
- Bender Stephan
- Bene Judit
- Bergen Sarah E
- Berrettini Wade H
- Bevilacqua Elizabeth
- Biernacka Joanna M
- Bigdeli Tim B
- Black Donald W
- Blackburn Hannah
- Blackwell Jenefer M
- Blackwood Douglas HR
- Boehnke Michael
- Boks Marco
- Boocock James
- Borglum Anders D
- Bramon Elvira
- Breen Gerome
- Brown Matthew A
- Bruggeman Richard
- Buccola Nancy G
- Buckner Randy L
- Budde Monika
- Bulik-Sullivan Brendan
- Bumpstead Suzannah J
- Bunney William
- Burmeister Margit
- Buxbaum Joseph D
- Bybjerg-Grauholm Jonas
- Byerley William
- Cahn Wiepke
- Cai Guiqing
- Cairns Murray J
- Campion Dominique
- Cantor Rita M
- Carr Vaughan J
- Carrera Noa
- Casas Juan P
- Casas Miquel
- Case-Control Wellcome Trust
- Catts Stanley V
- Cervantes Pablo
- Chambert Kimberley D
- Chan Raymond CK
- Charney Alexander W
- Chen Eric YH
- Chen Ronald YL
- Cheng Wei
- Cheung Eric FC
- Chong Siow Ann
- Cichon Sven
- Clarke Toni-Kim
- Cloninger C Robert
- Cohen David
- Cohen Nadine
- Coleman Jonathan RI
- Collier David A
- Consortium Psychiat Genomics
- Consortium Psychiat Genomics
- Cormican Paul
- Corvin Aiden
- Coryell William
- Craddock Nicholas
- Craig David W
- Crespo-Facorro Benedicto
- Crowley James J
- Cruceanu Cristiana
- Cuellar-Barboza Alfredo B
- Curtis David
- Czerski Piotr M
- Dale Anders M
- Daly Mark J
- Dannlowski Udo
- Darvasi Ariel
- Davidson Michael
- Davis Kenneth L
- de Haan Lieuwe
- de Leeuw Christiaan A
- Degenhardt Franziska
- Del Favero Jurgen
- DeLisi Lynn E
- Deloukas Panos
- Demontis Ditte
- DePaulo J Raymond
- Di Florio Arianna
- di Forti Marta
- Dikeos Dimitris
- Dinan Timothy
- Djurovic Srdjan
- Dobbyn Amanda L
- Domenici Enrico
- Donnelly Peter
- Donohoe Gary
- Drapeau Elodie
- Dronov Serge
- Duan Jubao
- Dudbridge Frank
- Duncanson Audrey
- Edenberg Howard
- Edkins Sarah
- Ehrenreich Hannelore
- Eichhammer Peter
- Elvsashagen Torbjorn
- Eriksson Johan
- Escott-Price Valentina
- Esko Tonu
- Essioux Laurent
- Etain Bruno
- Fan Chun Chieh
- Fanous Ayman H
- Farh Kai-How
- Farrell Martilias S
- Flickinger Matthew
- Foroud Tatiana M
- Forstner Andreas J
- Forty Liz
- Frank Josef
- Franke Lude
- Fraser Christine
- Freedman Robert
- Freeman Colin
- Freimer Nelson B
- Friedman Joseph I
- Fromer Menachem
- Frye Mark A
- Fullerton Janice M
- Gade Katrin
- Garnham Julie
- Gaspar Helena A
- Gejman Pablo V
- Genovese Giulio
- Georgieva Lyudmila
- Gershon Elliot S
- Giambartolomei Claudia
- Giannoulatou Eleni
- Giegling Ina
- Gill Michael
- Gillman Matthew
- Giusti-Rodriguez Paola
- Godard Stephanie
- Goes Fernando
- Goldstein Jacqueline I
- Gopal Srihari
- Gordon Scott D
- Gordon-Smith Katherine
- Gratten Jacob
- Gray Emma
- Green Elaine K
- Green Melissa J
- Greenwood Tiffany A
- Grigoroiu-Serbanescu Maria
- Grove Jakob
- Guan Weihua
- Gurling Hugh
- Gwilliam Rhian
- Hall Jeremy
- Hall Mei-Hua
- Hammer Christian
- Hammond Naomi
- Hamshere Marian L
- Hansen Christine Soholm
- Hansen Mark
- Hansen Thomas
- Haroutunian Vahram
- Hartmann Annette M
- Hauser Joanna
- Hautzinger Martin
- Heilbronner Urs
- Hellenthal Garrett
- Henskens Frans A
- Herms Stefan
- Hipolito Maria
- Hirschhorn Joel N
- Hoffmann Per
- Hollegaard Mads V
- Holmans Peter A
- Hougaard David M
- Huang Hailiang
- Huckins Laura
- Hultman Christina M
- Hunt Sarah E
- Ikeda Masashi
- Inter Psychosis Endophenotypes
- Iwata Nakao
- Iyegbe Conrad
- Jablensky Assen V
- Jamain Stephane
- Jankowski Janusz
- Jayakumar Alagurevathi
- Joa Inge
- Jones Ian
- Jones Lisa A
- Jonsson Erik G
- Jr Belliveau Richard A
- Jr Macek Milan
- Julia Antonio
- Jureus Anders
- Kahler Anna K
- Kahn Rene S
- Kalaydjieva Luba
- Kalman Janos L
- Kandaswamy Radhika
- Karachanak-Yankova Sena
- Karjalainen Juha
- Karlsson Robert
- Kavanagh David
- Keller Matthew C
- Kelly Brian J
- Kelsoe John
- Kendler Kenneth S
- Kennedy James L
- Keong Jimmy Lee Chee
- Khrunin Andrey
- Kim Yunjung
- Kirov George
- Kittel-Schneider Sarah
- Klovins Janis
- Knight Jo
- Knott Sarah V
- Knowles James A
- Kogevinas Manolis
- Konte Bettina
- Kravariti Eugenia
- Kucinskas Vaidutis
- Kucinskiene Zita Ausrele
- Kupka Ralph
- Kuzelova-Ptackova Hana
- Landen Mikael
- Langford Cordelia
- Laurent Claudine
- Lawrence Jacob
- Lawrie Stephen
- Lawson William B
- Leber Markus
- Leboyer Marion
- Lee Phil H
- Lee S Hong
- Legge Sophie E
- Lencz Todd
- Lerer Bernard
- Levinson Douglas F
- Levy Shawn E
- Lewis Cathryn M
- Li Jun Z
- Li Miaoxin
- Li Qingqin S
- Li Tao
- Liang Kung-Yee
- Liddle Jennifer
- Lieberman Jeffrey
- Limborska Svetlana
- Lin Kuang
- Linszen Don H
- Lissowska Jolanta
- Liu Chunyu
- Liu Jianjun
- Lonnqvist Jouko
- Loohuis Loes M Olde
- Loughland Carmel M
- Lubinski Jan
- Lucae Susanne
- MacIntyre Donald J
- Magnusson Patrik KE
- Maher Brion S
- Mahon Pamela B
- Maier Wolfgang
- Malhotra Anil K
- Mallet Jacques
- Malt Ulrik F
- Markus Hugh S
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- Metspalu Andres
- Michie Patricia T
- Milani Lili
- Milanova Vihra
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- Montgomery Grant W
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- Muller-Myhsok Bertram
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- Murray Robin M
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- Olsen Line
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- Palotie Aarno
- Pantelis Christos
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- Papiol Sergi
- Parkhomenko Elena
- Parra Jose Guzman
- Pato Carlos
- Pato Michele T
- Paunio Tiina
- Pavlides Jennifer M Whitehead
- Pearson Richard
- Pedersen Carsten Bocker
- Pedersen Marianne Giortz
- Perkins Diana O
- Perlis Roy H
- Perry Amy
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- Pfennig Andrea
- Picchioni Marco
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- Potter Simon C
- Powell John
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- Ricketts Michelle
- Rietschel Marcella
- Riley Brien P
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- Rivas Fabio
- Rivera Margarita
- Roffman Joshua L
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- Roussos Panos
- Ruderfer Douglas M
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- Salomaa Veikko
- Sanchez-Mora Cristina
- Sanders Alan R
- Sawcer Stephen J
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- Schatzberg Alan F
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- Schork Nicholas J
- Schulze Thomas G
- Schwab Sibylle G
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- Shi Jianxin
- Shilling Paul D
- Sigurdsson Engilbert
- Silverman Jeremy M
- Sim Kang
- Sklar Pamela
- Slaney Claire
- Slominsky Petr
- Smeland Olav B
- Smoller Jordan W
- So Hon-Cheong
- Sobell Janet L
- Soderman Erik
- Spencer Chris CA
- Spijker Anne T
- St Clair David
- Stahl Eli A
- Stefansson Hreinn
- Stefansson Kari
- Steinberg Stacy
- Stogmann Elisabeth
- Stordal Eystein
- Strange Amy
- Straub Richard E
- Strauss John S
- Streit Fabian
- Strengman Eric
- Strohmaier Jana
- Stroup T Scott
- Su Zhan
- Subramaniam Mythily
- Sullivan Patrick F
- Suvisaari Jaana
- Svrakic Dragan M
- Szatkiewicz Jin P
- Szelinger Szabolcs
- Tashakkori-Ghanbaria Avazeh
- Thirumalai Srinivas
- Thompson Robert C
- Thorgeirsson Thorgeir E
- Toncheva Draga
- Tooney Paul A
- Tosato Sarah
- Toulopoulou Timothea
- Trembath Richard C
- Treutlein Jens
- Trubetskoy Vassily
- Trubetskoy Vassily
- Turecki Gustavo
- Vaaler Arne E
- Van Os Jim
- Vedder Helmut
- Vieta Eduard
- Vincent John
- Visscher Peter M
- Viswanathan Ananth C
- Vukcevic Damjan
- Waddington John
- Waller Matthew
- Walsh Dermot
- Walshe Muriel
- Walters James TR
- Wang Dai
- Wang Qiang
- Wang Weiqing
- Wang Yunpeng
- Watson Stanley J
- Webb Brad-Ley T
- Weickert Cynthia Shannon
- Weickert Thomas W
- Weinberger Daniel R
- Weisbrod Matthias
- Weiser Mark
- Werge Thomas
- Weston Paul
- Whittaker Pamela
- Widaa Sara
- Wiersma Durk
- Wildenauer Dieter B
- Williams Nigel M
- Williams Stephanie
- Witt Stephanie H
- Wolen Aaron R
- Wong Emily HM
- Wood Nicholas W
- Wormley Brandon K
- Wray Naomi R
- Wu Jing Qin
- Xi Simon
- Xu Wei
- Young Allan H
- Zai Clement C
- Zandi Peter
- Zhang Peng
- Zheng Xuebin
- Zimprich Fritz
- Zollner Sebastian
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2018
- Field of study
publisher: Elsevier articletitle: Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes journaltitle: Cell articlelink: https://doi.org/10.1016/j.cell.2018.05.046 content_type: article copyright: © 2018 Elsevier Inc
Evaluation of appendicitis risk prediction models in adults with suspected appendicitis
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- Abbas Sh
- Abbas Sh
- Abbassi Oa
- Abbott T
- Abdelgadir Am
- Abdelrahman A
- Abdelrahman M
- Abdelrahman M
- Abdelwahed A
- Abellan M
- Abellán Am
- Abellán Am
- Abulafi M
- Acharya A
- Acosta A
- Adam Me
- Adams Re
- Adegbola So
- Adegbola So
- Adimonye A
- Adnan M
- Afshar S
- Agresta F
- Agua Ia
- Aguayo Jl
- Agudo Ar
- Ahad A
- Ahel J
- Ahern Dp
- Ahmad A
- Ahmed B
- Ahmed G
- Ahmed Os
- Ahmed Os
- Ahmed S
- Ainsworth P
- Ais G
- Ais G
- Aisoni F
- Akbari K
- Akhtar K
- Akinsola O
- Akram F
- Al-Faham Z
- Al-Khafaji N
- Al-Khyatt W
- Al-Musawi S
- Al-Sarireh B
- Al-Sheikh M
- Alagna V
- Alani M
- Alberca-Paramo A
- Aldrey I
- Alexander R
- Alhammali T
- Alhammali T
- Ali M
- Aljorfi A
- Allen M
- Allington J
- Alonzo A
- Alshafei A
- Altomare Ma
- Alvarez Cm
- Alvarez E
- Alvarez-Gallego M
- Amaducci E
- Amarasinghe R
- Amayo A
- Ambrona-Zafra D
- Amin V
- Ammendola M
- Amtul N
- Amtul N
- Amuthalingam T
- Anandan L
- Anania G
- Anania M
- Anderson Dj
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- Andreani Sm
- Andreani Sm
- Andrews B
- Ang A
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- Angelieri D
- Angelini M
- Angrisani M
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- García-Gutierrez C
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- Redondo E
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- Reese G
- Regina G
- Rehman S
- Rehman S
- Rekhraj S
- Ren Kz
- Renshaw S
- Renshaw S
- Renzi Cr
- Resende Fm
- Rezacova M
- Rezvani S
- Riaz W
- Riba-Combatti L
- Ribaudo M
- Ribeiro B
- Rich Je
- Richardson Td
- Ridaura N
- Riera E
- Rigby S
- Rigney B
- Rinkoff S
- Ripoli Mc
- Robb Hd
- Robertson C
- Robinson A
- Robinson A
- Robinson D
- Robinson D
- Rocha R
- Rodger V
- Rodicio-Miravalles Jl
- Rodriguez L
- Rodriguez-Lopez M
- Rodriguez-Lopez M
- Rodriguez-Lopez M
- Rodríguez Ec
- Rojo Ja
- Roldán-Ortiz S
- Rolph R
- Romano J
- Romano R
- Romario Uf
- Romoli L
- Roncero Ls
- Ronda Rn
- Roomi S
- Rosa Mj
- Rosat A
- Roscio F
- Roscio F
- Roscio F
- Rossi C
- Rossi D
- Rossi Gm
- Roth N
- Rothnie K
- Roxburgh C
- Roy C
- Ruano A
- Rubbini M
- Rudland I
- Ruffolo C
- Rufo E
- Ruggiu Gv
- Ruiz-Marín M
- Ruiz-Marín M
- Rupani S
- Rupasinghe Sn
- Rupasinghe Sn
- Rutherford Dg
- Ruzvidzo F
- Ruzzenente A
- Saad M
- Saad M
- Saavedra-Chacón M
- Saba A
- Sabia D
- Sacco R
- Sacks R
- Sadek S
- Saghir N
- Sagnotta A
- Sagnotta A
- Saha A
- Sahay Sj
- Sahnan K
- Sahnan K
- Sainz B
- Sainz B
- Sajid Ms
- Salama Y
- Salamone G
- Salamone G
- Salamone G
- Salamone G
- Salandini Mc
- Salem A
- Salim S
- Salva Ab
- Salvador H
- Samartin C
- Sammarco G
- Sammarco G
- Samuel M
- Sana S
- Sanchez Er
- Sanchez Er
- Sanchez L
- Sanchez-Garcia S
- Sanchez-Guillen L
- Sanchez-Guillen L
- Sanchez-Martinez A
- Sancho-Muriel J
- Sandu L
- Sanna S
- Santamaria C
- Santamaría Pc
- Santarrufina-Martínez S
- Santos Sc
- Santurro L
- Sanz-Navarro S
- Sarmah P
- Sarmah P
- Sarmah P
- Sarveswaran J
- Sasia D
- Sasia D
- Saunders S
- Savill A
- Savino G
- Savino G
- Savioli F
- Scabini S
- Scabini S
- Scabini S
- Scandroglio Is
- Scanlon K
- Scatizzi M
- Scialandrone G
- Scricciolo M
- Sebastian Jf
- Sebastián-Tomás Jc
- Seddon Tc
- Segalini E
- Segura-Sampedro Jj
- Sena G
- Sena-Ruiz F
- Seneviratne N
- Sepe C
- Serventi F
- Serventi F
- Seth M
- Setshwaelo T
- Sezen E
- Sgardelis P
- Sgrò A
- Sgrò A
- Sgrò A
- Shah J
- Shah K
- Shah Sm
- Shah Sm
- Shaikh Ia
- Shakoor Z
- Shanmuganathan V
- Shanmugarajah K
- Sharma A
- Sharma A
- Sharma P
- Sharp Ol
- Sharp Ol
- Shaw Av
- Shepherd Ja
- Sherif Ma
- Shet S
- Shetty Vd
- Shingler G
- Shiwani Mh
- Shrestha D
- Shurlock J
- Sian T
- Siaw O
- Siddique K
- Siddiqui Mn
- Siddiqui Za
- Sierra-Grañón Je
- Siggens Kl
- Sihra N
- Silva A
- Silva I
- Silvestri V
- Simioni A
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- Simmonds L
- Simo V
- Simoes J
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- Singh J
- Singh P
- Singh S
- Singhal T
- Singhal T
- Sivaloganathan P
- Skalamera I
- Skerritt C
- Slezak I
- Smallcombe N
- Smart Cj
- Smart Cj
- Smart Nj
- Smart Nj
- Smoker H
- Soares A. S.
- Soares As
- Soares As
- Soares As
- Soares As
- Soares As
- Soh B
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- Soliani P
- Solinas L
- Sooriyamoorthy T
- Soria-Aledo V
- Soria-Aledo V
- Soriano Jt
- Sorrentino L
- Sousa Hs
- Souter J
- Sparta C
- Spaziani A
- Speake D
- Speake D
- Springate El
- Sreedharan L
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- Staderini F
- Stecca T
- Stella M
- Stephens Gf
- Stephens Gf
- Stevenson R
- Stewart Dj
- Stoica I
- Storey R
- Stoyanov Ti
- Strachan E
- Strange Ja
- Stubbs Bm
- Stupalkowska W
- Stupalkowska W
- Suarez-Cabrera A
- Suero Ca
- Sultana A
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- Sunter H
- Surg Pt
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- Suárez-Sánchez A
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- Symons N
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- Szucs A
- Szucs A
- Sánchez-Cifuentes A
- Sánchez-Fuentes Mn
- Sánchez-Rubio M
- Tabain V
- Taglietti L
- Tague Le
- Tahir W
- Tailor K
- Tallon-Aguilar L
- Tallon-Aguilar L
- Tamayo-López Mj
- Tamborska A
- Tamini N
- Tamini N
- Tamini N
- Tan Cy
- Tan Cy
- Tan E
- Tan Hl
- Tan S
- Tang Am
- Tapiolas I
- Tarazi M
- Tatulli F
- Tay Yh
- Tayeh S
- Taylor M
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- Taylor Ns
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- Tezas S
- Thaha Ma
- Thakral N
- Thakur D
- Thava B
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- Thaventhiran Aj
- Theodoropoulou K
- Thomas At
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- Vallve-Bernal M
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- Vigorita V
- Vijay V
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- Viviani E
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- Vulcano I
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- Yang P
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- Yeung K
- Yoganathan S
- Yoong S
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- Zelazek M
- Zerpa C
- Zhang Ay
- Zhou S
- Zorrilla L
- Zuin M
- Zurleni Tz
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2019
- Field of study
Background
Appendicitis is the most common general surgical emergency worldwide, but its diagnosis remains challenging. The aim of this study was to determine whether existing risk prediction models can reliably identify patients presenting to hospital in the UK with acute right iliac fossa (RIF) pain who are at low risk of appendicitis.
Methods
A systematic search was completed to identify all existing appendicitis risk prediction models. Models were validated using UK data from an international prospective cohort study that captured consecutive patients aged 16–45 years presenting to hospital with acute RIF in March to June 2017. The main outcome was best achievable model specificity (proportion of patients who did not have appendicitis correctly classified as low risk) whilst maintaining a failure rate below 5 per cent (proportion of patients identified as low risk who actually had appendicitis).
Results
Some 5345 patients across 154 UK hospitals were identified, of which two‐thirds (3613 of 5345, 67·6 per cent) were women. Women were more than twice as likely to undergo surgery with removal of a histologically normal appendix (272 of 964, 28·2 per cent) than men (120 of 993, 12·1 per cent) (relative risk 2·33, 95 per cent c.i. 1·92 to 2·84; P < 0·001). Of 15 validated risk prediction models, the Adult Appendicitis Score performed best (cut‐off score 8 or less, specificity 63·1 per cent, failure rate 3·7 per cent). The Appendicitis Inflammatory Response Score performed best for men (cut‐off score 2 or less, specificity 24·7 per cent, failure rate 2·4 per cent).
Conclusion
Women in the UK had a disproportionate risk of admission without surgical intervention and had high rates of normal appendicectomy. Risk prediction models to support shared decision‐making by identifying adults in the UK at low risk of appendicitis were identified
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