DETEKSI SERANGAN PORT SCANNING MENGGUNAKAN ALGORITMA NAIVE BAYES

Serangan Port Scanning dapat menjadi masalah untuk kedepannya bagi jaringan jika tidak diatasi karena dapat merusak sistem dengan melakukan serangan lanjutan. Port Scanning memiliki dua tipe serangan yaitu non stealth scan dan stealth scan, stealh scan merupakan jenis port scanning yang lebih berbahaya dari pada non stealth scan. Stealh scan merupakan serangan yang dapat dianggap aktivitas normal bagi pendeteksi serangan, untuk itu dibutuhkan suatu teknik untuk mengenali ciri dari serangan stealh scan. Peneliti mengklasifikasi serangan stealh scan berdasarkan tiga jenis yaitu FIN scan, NULL scan dan XMAS scan, untuk mengenali ciri dari serangan tersebut dibutuhkan klasifikasi dari pola serangan dari tiga jenis tersebut. Peneliti menggunakan algoritma naive bayes untuk mengklasifikasikan ketiga jenis tersebut berdasarkan pola serangan. Pada paper ini peneliti akan membuat skenario sendiri untuk mengambil datasetnya dan setelah itu dataset akan diubah file nya melalui proses featue extraction. Tujuan dari feature extraction itu sendiri untuk mengubah file .pcap menjadi .csv, file .csv berguna untuk mempermudah peneliti mengenali pola dari serangan stealh scan. Pada penelitian ini setelah didapat pola serangan yang didapat dari informasi paket yang berasal dari tcp header dan ip header, pola tersebut peniliti amati dan dicari nilai probabilitasnya. Setelah didapat nilai probabilitasnya peneliti merancang sistem IDS menggunakan bahasa python dan mengimplementasikan algoritma naive bayes. Peneliti melakukan pengujian sistem IDS menggunakan naïve bayes sebanyak 10 kali. Hasil dari penelitian ini sendiri mendapatkan bahwa akurasi naive bayes sangat baik dalam deteksi dan pengklasifikasian berdasarkan jenis serangan dengan hasil untuk rata-rata akurasi FIN scan 99.04%, NULL scan 98.94%, XMAS scan 99.13% dan all out attack sebesar 99.10

Systematic model identification and optimization-based active polymorphic control of crystallization processes

Polymorphism is an important issue in industrial crystallization, since polymorphs of the same compound can present very different properties, such as solubility, melting point or density, influencing considerably the manufacturability and bioavailability of the final product. This work proposes a model-based active polymorphic control strategy that allows obtaining large crystals of the stable polymorph at the end of a batch crystallization process, even in the case of erroneous seeding or in situ nucleation of a mixture of both the stable and metastable forms. A novel systematic experimental design was applied to estimate the kinetic parameters of dissolution, growth and secondary nucleation of the stable and metastable polymorphs of the model compound (ortho-aminobenzoic acid, OABA). Such experimental approach allows the determination of the studied kinetics without any correlation between parameters during the estimation, and without the need of off-line measurements of the crystal size distribution during the experiments. The estimated kinetic parameters were used to build a population balance model for the calculation of the optimal temperature profile needed, during a batch cooling crystallization process, for the (i) elimination of the metastable form crystals nucleated in situ or erroneously seeded and the (ii) maximisation of the size of the crystals of the stable polymorph obtained at the end of the batch process

The Opitz syndrome gene product MID1 assembles a microtubule-associated ribonucleoprotein complex

Abstract Opitz BBB/G syndrome (OS) is a heterogenous malformation syndrome mainly characterised by hypertelorism and hypospadias. In addition, patients may present with several other defects of the ventral midline such as cleft lip and palate and congenital heart defects. The syndrome-causing gene encodes the X-linked E3 ubiquitin ligase MID1 that mediates ubiquitin-specific modification and degradation of the catalytic subunit of the translation regulator protein phosphatase 2A (PP2A). Here, we show that the MID1 protein also associates with elongation factor 1α (EF-1α) and several other proteins involved in mRNA transport and translation, including RACK1, Annexin A2, Nucleophosmin and proteins of the small ribosomal subunits. Mutant MID1 proteins as found in OS patients lose the ability to interact with EF-1α. The composition of the MID1 protein complex was determined by several independent methods: (1) yeast two-hybrid screening and (2) immunofluorescence, (3) a biochemical approach involving affinity purification of the complex, (4) co-fractionation in a microtubule assembly assay and (5) immunoprecipitation. Moreover, we show that the cytoskeleton-bound MID1/translation factor complex specifically associates with G- and U-rich RNAs and incorporates MID1 mRNA, thus forming a microtubule-associated ribonucleoprotein (RNP) complex. Our data suggest a novel function of the OS gene product in directing translational control to the cytoskeleton. The dysfunction of this mechanism would lead to malfunction of microtubule-associated protein translation and to the development of OS. Electronic supplementary material The online version of this article (doi:10.1007/s00439-007-0456-6) contains supplementary material, which is available to authorized users