THE IMPACT OF VARIOUS INDIAN MEDICINAL PLANTS AS A WOUNDS HEALER

Many requirements of human beings are fulfilled by the plants. They also prevent and cure various diseases of human beings including wounds and ulcers. Plants and their extracts have immense potential for the management and treatment of wounds. The management of wound has been a major problem since the early stages of medical science. In spite of brilliant progress of in surgery, wound management still remains a subject of speculation. The early manifestation of unsatisfactory wound healing gives rise to serious complications which can lead to prolonged healing and even death in surgical practice. These natural medicines for wound healing are cheap, affordable and purportedly safe as hyper sensitive reactions are rarely encountered with the use of these agents. These natural agents induce healing and regeneration of the lost tissue by multiple mechanisms. However, there is a need for scientific validation, standardization and safety evaluation of plants of the traditional medicine recommended for healing of the wounds

RIDDHI (HABENARIA INTERMEDIA D. WEAR): SIGNIFICANCE AND VERSATILITY IN VARIOUS ANCIENT AYURVEDIC NIGHNATU SCRIPTURES

In Ayurveda treatment combines products derived from plants, animal, mineral, etc. Amongst all types of Ayurvedic preparations plant-based preparations play a significant and important role in the Ayurvedic healing process. Healing with medicinal plants is as old as mankind itself. We have been using medicinal plants since extremely long time. The use of plant based medicinal products and supplements have increased tremendously over the past three decades. Ṛddhi is an important member of Aṣṭavarga group of plants. Traditionally it is used in many herbal preparations for its rejuvenating and health promoting properties. Polyherbal formulation containing tubers of this herb possess properties viz. full of vital energy, high in antioxidants, and boosting immunity. The demand of this herb is increasing day by day but due to scarcity of this plant in wild, unaware about authentic botanical source, non-existing cultivation practices there is widespread problem of adulteration or substitution with other plants. So by taking into account the above situation this systematic review has conducted to find out authentic botanical source of Ṛddhi

HYBRID AC/MT-HVDC TRANSMISSION LINES AND ITS EFFECTIVE OPERATION USING ENHANCED-FISH SWARM OPTIMIZER

Multi-Terminal-High Voltage Direct Current (MT-HVDC) transmission lines are used to transmit electricity over long distances with lower losses compared to traditional Alternating Current (AC) transmission lines. However, HVDC transmission lines have limitations in terms of their ability to handle AC system faults and the need for expensive AC/DC converters at each end of the line. To address these limitations, a hybrid AC/MT-HVDC transmission line can be used. This type of transmission line combines the benefits of both AC and DC transmission, allowing for more efficient and reliable operation. In this article, an Enhanced-Fish Swarm Optimizer (E-FSO) is presented for the efficient maintenance of hybrid AC/MT-HVDC transmission lines. An external repository is included in the proposed E-FSO to preserve that is not dominant. Additionally, fuzzy decision-making is used to choose the hybrid AC/HVDC transmission lines' optimal compromise operating point. In these systems, in addition to the complete control of AC line through parameters for the dedicated generators and transformers connections, and Volt-Ampere Reactive (VAR) compensations, the Voltage Source Converters (VSCs) action and response controllable voltage is engaged. The outcomes of the experiment show the efficacy and dominance of the suggested algorithm, which has high stability indices compared to several competitive algorithms. Nevertheless, the suggested E-FSO is effective in producing a compromise operating point that satisfies the operator's needs while also obtaining well-diversified solutions

Development of Region Specific Hybrid Goat and their Performance Evaluation under High Altitude Condition

Goat meat (chevon) comprises an important source of protein to provide essential amino acids in addition to other meat and plant sources of proteins. Therefore, demands for chevon are huge from civil and defence sector in this region. However, there is limited availability of fresh tender chevon in Ladakh region round the year. Hence, there was a need of augmenting local availability of fresh goat meat by developing animal technology for fast growing region-specific crossbred goat for meat purpose that can efficiently perform under adverse climatic conditions prevailing in this region. The present crossbred goat was developed by using mixing genes of adaptive and meat traits through cross breeding between local goats (Changthangi and Gaddi breeds of goats) and Sirohi/Black Bengal goats. To develop this technology, we introduced Black Bengal and Sirohi from plain areas and native breed of goats viz. Gaddi and Changthangi goats for further adaptation and growth performance studies at Leh-Ladakh. After initial studies goats were divided into high altitude resistant/adapted and susceptible groups. High altitude resistant/adapted goats were taken for further cross breeding and pure breeding. All the kids produced out of this breeding were studied for physiological responses, growth performance, and blood biochemical parameters to know their adaptive and growth performance at high altitude. Crossbred kids of Sirohi ♂/Black Bengal ♂ X Changthangi ♀ had significantly (P<0.05) higher weight gain, adaptive physiological responses and blood biochemicals level as compared to exotic pure bred and other cross bred kids. These crossbred kids attained market weight faster than local as well as breeds from plain areas (Sirohi and Black Bengal goats). Average meat yield is 7-10 kg per adult crossbred goat if slaughtered at 9-12 month age. These cross bred (broiler goat) may be reared at Leh-Ladakh for meat purpose. Hence, this animal technology may help in increasing of fresh goat meat (chevon) supply to meet army’s and civil requirements in Leh-Ladakh

Diarrhea, Pneumonia, and Infectious Disease Mortality in Children Aged 5 to 14 Years in India

Background: Little is known about the causes of death in children in India after age five years. The objective of this study is to provide the first ever direct national and sub-national estimates of infectious disease mortality in Indian children aged 5 to 14 years. Methods: A verbal autopsy based assessment of 3 855 deaths is children aged 5 to 14 years from a nationally representative survey of deaths occurring in 2001–03 in 1?1 million homes in India. Results: Infectious diseases accounted for 58 % of all deaths among children aged 5 to 14 years. About 18 % of deaths were due to diarrheal diseases, 10 % due to pneumonia, 8 % due to central nervous system infections, 4 % due to measles, and 12 % due to other infectious diseases. Nationally, in 2005 about 59 000 and 34 000 children aged 5 to 14 years died from diarrheal diseases and pneumonia, corresponding to mortality of 24?1 and 13?9 per 100 000 respectively. Mortality was nearly 50 % higher in girls than in boys for both diarrheal diseases and pneumonia. Conclusions: Approximately 60 % of all deaths in this age group are due to infectious diseases and nearly half of these deaths are due to diarrheal diseases and pneumonia. Mortality in this age group from infectious diseases, and diarrhea i

Forward-central two-particle correlations in p-Pb collisions at root s(NN)=5.02 TeV

Two-particle angular correlations between trigger particles in the forward pseudorapidity range (2.5 2GeV/c. (C) 2015 CERN for the benefit of the ALICE Collaboration. Published by Elsevier B. V.Peer reviewe

Event-shape engineering for inclusive spectra and elliptic flow in Pb-Pb collisions at root(NN)-N-S=2.76 TeV

Peer reviewe

Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

A double burden of malnutrition occurs when individuals, household members or communities experience both undernutrition and overweight. Here, we show geospatial estimates of overweight and wasting prevalence among children under 5 years of age in 105 low- and middle-income countries (LMICs) from 2000 to 2017 and aggregate these to policy-relevant administrative units. Wasting decreased overall across LMICs between 2000 and 2017, from 8.4% (62.3 (55.1–70.8) million) to 6.4% (58.3 (47.6–70.7) million), but is predicted to remain above the World Health Organization’s Global Nutrition Target of <5% in over half of LMICs by 2025. Prevalence of overweight increased from 5.2% (30 (22.8–38.5) million) in 2000 to 6.0% (55.5 (44.8–67.9) million) children aged under 5 years in 2017. Areas most affected by double burden of malnutrition were located in Indonesia, Thailand, southeastern China, Botswana, Cameroon and central Nigeria. Our estimates provide a new perspective to researchers, policy makers and public health agencies in their efforts to address this global childhood syndemic

Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: A systematic analysis for the Global Burden of Disease Study 2017

Background: The Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017) includes a comprehensive assessment of incidence, prevalence, and years lived with disability (YLDs) for 354 causes in 195 countries and territories from 1990 to 2017. Previous GBD studies have shown how the decline of mortality rates from 1990 to 2016 has led to an increase in life expectancy, an ageing global population, and an expansion of the non-fatal burden of disease and injury. These studies have also shown how a substantial portion of the world's population experiences non-fatal health loss with considerable heterogeneity among different causes, locations, ages, and sexes. Ongoing objectives of the GBD study include increasing the level of estimation detail, improving analytical strategies, and increasing the amount of high-quality data. Methods: We estimated incidence and prevalence for 354 diseases and injuries and 3484 sequelae. We used an updated and extensive body of literature studies, survey data, surveillance data, inpatient admission records, outpatient visit records, and health insurance claims, and additionally used results from cause of death models to inform estimates using a total of 68 781 data sources. Newly available clinical data from India, Iran, Japan, Jordan, Nepal, China, Brazil, Norway, and Italy were incorporated, as well as updated claims data from the USA and new claims data from Taiwan (province of China) and Singapore. We used DisMod-MR 2.1, a Bayesian meta-regression tool, as the main method of estimation, ensuring consistency between rates of incidence, prevalence, remission, and cause of death for each condition. YLDs were estimated as the product of a prevalence estimate and a disability weight for health states of each mutually exclusive sequela, adjusted for comorbidity. We updated the Socio-demographic Index (SDI), a summary development indicator of income per capita, years of schooling, and total fertility rate. Additionally, we calculated differences between male and female YLDs to identify divergent trends across sexes. GBD 2017 complies with the Guidelines for Accurate and Transparent Health Estimates Reporting. Findings: Globally, for females, the causes with the greatest age-standardised prevalence were oral disorders, headache disorders, and haemoglobinopathies and haemolytic anaemias in both 1990 and 2017. For males, the causes with the greatest age-standardised prevalence were oral disorders, headache disorders, and tuberculosis including latent tuberculosis infection in both 1990 and 2017. In terms of YLDs, low back pain, headache disorders, and dietary iron deficiency were the leading Level 3 causes of YLD counts in 1990, whereas low back pain, headache disorders, and depressive disorders were the leading causes in 2017 for both sexes combined. All-cause age-standardised YLD rates decreased by 3·9% (95% uncertainty interval [UI] 3·1-4·6) from 1990 to 2017; however, the all-age YLD rate increased by 7·2% (6·0-8·4) while the total sum of global YLDs increased from 562 million (421-723) to 853 million (642-1100). The increases for males and females were similar, with increases in all-age YLD rates of 7·9% (6·6-9·2) for males and 6·5% (5·4-7·7) for females. We found significant differences between males and females in terms of age-standardised prevalence estimates for multiple causes. The causes with the greatest relative differences between sexes in 2017 included substance use disorders (3018 cases [95% UI 2782-3252] per 100 000 in males vs 1400 [1279-1524] per 100 000 in females), transport injuries (3322 [3082-3583] vs 2336 [2154-2535]), and self-harm and interpersonal violence (3265 [2943-3630] vs 5643 [5057-6302]). Interpretation: Global all-cause age-standardised YLD rates have improved only slightly over a period spanning nearly three decades. However, the magnitude of the non-fatal disease burden has expanded globally, with increasing numbers of people who have a wide spectrum of conditions. A subset of conditions has remained globally pervasive since 1990, whereas other conditions have displayed more dynamic trends, with different ages, sexes, and geographies across the globe experiencing varying burdens and trends of health loss. This study emphasises how global improvements in premature mortality for select conditions have led to older populations with complex and potentially expensive diseases, yet also highlights global achievements in certain domains of disease and injury

Elliptic flow of muons from heavy-flavour hadron decays at forward rapidity in Pb-Pb collisions at root s(NN)=2.76TeV

The elliptic flow, v(2), of muons from heavy-flavour hadron decays at forward rapidity (2.5 <y <4) is measured in Pb-Pb collisions at root s(NN)= 2.76TeVwith the ALICE detector at the LHC. The scalar product, two- and four-particle Q cumulants and Lee-Yang zeros methods are used. The dependence of the v(2) of muons from heavy-flavour hadron decays on the collision centrality, in the range 0-40%, and on transverse momentum, p(T), is studied in the interval 3 <p(T)<10 GeV/c. A positive v(2) is observed with the scalar product and two-particle Q cumulants in semi-central collisions (10-20% and 20-40% centrality classes) for the p(T) interval from 3 to about 5GeV/c with a significance larger than 3 sigma, based on the combination of statistical and systematic uncertainties. The v(2) magnitude tends to decrease towards more central collisions and with increasing pT. It becomes compatible with zero in the interval 6 <p(T)<10 GeV/c. The results are compared to models describing the interaction of heavy quarks and open heavy-flavour hadrons with the high-density medium formed in high-energy heavy-ion collisions. (C) 2015 CERN for the benefit of the ALICE Collaboration. Published by Elsevier B.V.Peer reviewe