Ayurvedic Management of Visarpa w.s.r to Herpes Zoster

Visarpa is one of the major Skin disease which is widely explained in our Ayurvedic classics. The clinical features contemplates with Herpes Zoster which is an active transmitting Viral disease. This case reports shows the Successful treatment of Visarpa. Here presenting a case of 72 year, female with sudden onset of 2-3 Vesicles on an Erthyematous base over the chin and left half of the lower lip, along with dragging pain and burning sensation within 2 days. Gradually Vesicles started to appear over the left side of the face, left Ear, Tongue with increased number of Vesicles within 4-5days along with other symptoms persists. Clinically the patient was diagnosed as Visarpa (Herpes Zoster). As Pitta Dosha and Raktha Dhathu vitiation was noticed, managed by Siravyadha as Shodhananga chikitsa and the Dravyas with Tiktha Rasa, Sheetha veerya in nature. The patient showed improvement within 15days of Treatment. The detailed case is presented in the full paper

Pharmaceutical and Physico-Chemical Study of Shilajit Bhasma

Although there were mention of Shilajit Bhasma (Calx) in various classical texts, but no specific study or usage of the same found mention in Google Scholar, ARD, Pub-Med, NCBI, AYUSH Research Portal and other open source database. This study is intended for preparation of Shilajit Bhasma (Calx) and assessments of physico-chemical properties of the same. Methods: The Bhasma (Calx) of Shilajit was being prepared using classical references, from Shilajit purified with two different methods, namely, Ushna Jal Shodhita Shilajit (Agnitapi) and Triphala Kwatha (decoction) Shodhit Shilajit (Suryatapi). Main constituents used in Marana (incineration) were purified Gandhak (sulphur), Haritala (orpiment), Manasila (realgar) in equal proportion to Shilajit. IEC No. for the study is IEC-RAC-18/R.S.B.K.-18-M.D.(Ayu.). Results: Result of the FE-SEM shows that both samples contain crystalline of nano size, with size ranged from 100nm – 1µm, with irregular shape and sizes. The findings of FE-SEM are in concordance to results of classical examinations of Bhasma (Calx). XRD intensity plots of both samples show various sharp and small peaks, when diffraction patterns were observed at different 2ɵ angles ranges from 10° to 70°, various peaks identified to correspond with known peaks for S & AsS and have been marked on the plots. ICP-MS and flame photometry of both samples reveals the presence of Na, Ca, K, Mg, Mn & As in different ratio. Conclusions: It has been concluded that the elemental composition of Shilajit Bhasma have a strong similarity with Purified Shilajit

Effect of Prathimarsa Nasya and Abhyanga on the Physical Fitness among Athletes in the Sports Hostel of Mar Basil Higher Secondary School Kothamangalam

Physical fitness has direct influence on athlete’s performance level. Sports medicine deals with the physical fitness and the treatment of injury related to sports and exercise by curative, rehabilitative and preventive modalities. Ayurveda the complete science of life can contribute in this field also. Abhyanga and Prathimarsa nasya are important Dinacharya procedures which play a key role in the maintenance of health and fitness of athletes. Regular Abhyanga controls Vata dosas and improves physical strength. Prathimarsa nasya improves the musculature of neck shoulder and chest. Ayurveda classics advice Abhyanga with Thila thailam and Prathimarsa Nasya with Anuthailam as a daily regimen for healthy individual. This study is being made to highlight the application of these Ayurveda Dinacharya procedures in promoting the physical fitness of sports persons. This study is a single group pre-post study. 47 subjects of age group 12–18 participating in athletic events were selected from the Sports Hostel of Mar Basil Higher Secondary School Kothamangalam as per the inclusion and exclusion criteria. After necessary investigations participants had been advised to follow the daily regimen Abhyanga with Thila Thaila after work out, half an hour before bath and Prathimarsa Nasyam with Anuthailam in morning, between 6am- 6.30am for 60 days continuously. Assessments were done on 31st day, 61st day and 91st day (follow up). Scores recorded for test items were converted into marks as per formula based on AAHPER fitness test chart and subjected to statistical analysis using repeated measure ANOVA test. Results showed that Pratimarsha nasya and Abhyanga have statistical significance in improving the physical fitness variables and overall performance level of athletes

Development of Analytical Profile of Ocimum sanctum L. leaves Powder prepared by Classical and Lyophilization method through Accelerated Stability Studies

Shelf life means the time period during which the potency of a drug remains unaffected from environmental factors or microbial contamination. Nowadays diverse procedures of making powder are available which affect on shelf life of them. Ocimum sanctum L. is most common household herb in Indian subcontinent. Hence, the present study is aimed to develop analytical profile of Ocimum sanctum L. leaves powder by classical and lyophilized method and compare the stability of both the samples. Materials and Methods: Ocimum sanctum L. leaves powder was prepared by two different drying methods and accelerated stability study was conducted as per ICH guideline Q1A (R2). Physicochemical analysis was repeated at interval of 0, 1, 3 and 6 months. Organoleptic parameters, microbial limits and heavy-metal analysis were observed at specific intervals. Result and Discussion: No significant changes were observed in organoleptic characters of both the samples up to storage of 6 months at accelerated condition. The values of physicochemical parameters of both the samples were within the prescribed limit specified in Ayurvedic Pharmacopeia of India. Results of Microbiological limit test were also below the limit and considerably decreased at specific intervals. Heavy metals namely arsenic, cadmium and mercury were not detected and lead was present below detectable limits. Conclusion: Analysis revealed that the classically prepared powder has better shelf life (3.08 years) than lyophilized powder (2.70 years) and also provides the modest and effective ways for optimal Eugenol extraction in accelerated conditions

Effect of Jala Neti and Soopya Yoosha in Allergic Rhinitis

Allergic rhinitis is a common health problem affecting immune system. It is an allergic response to specific allergens causing the inflammation of nasal mucosa. Allergic rhinitis is a major risk factor for poor asthma control and affects quality of life. Cardinal symptoms include nasal congestion, rhinorrhea, and pruritis of the nose and eyes. Patients who suffer from allergic rhinitis sustain significant morbidity and loss of productivity. The symptoms of allergic rhinitis can be co-related with Lakshanas of Pratishyaya mentioned in Ayurveda. This study aimed at yoga therapy and diet as an efficient treatment protocol for the disease. Jalaneti procedure which was mentioned in yoga, helped in preventing and managing upper respiratory tract infections. Since ancient time Yoosha had been suggested as Pathya for both healthy and diseased people. Soopya yoosha containing Mudga and Moolaka is a dietary preparation having Pratishyayahara property. In present study Jalaneti and Soopya yoosha were used in patients of allergic rhinitis

A Case Series on Importance of Rukshana Therapy in Spinal Pathology

Spinal pathologies like cervical spondylosis and lumbar spondylosis have become very much prevalent due to lifestyle and environmental factors. Neck pain and low back pain is the leading cause of years lived with disabilities. Ayurveda always insisted on intervening at the early stage of every disease so that the progress of pathology can be prevented. To counteract these conditions, Ayurveda has put forth six-fold treatment methodologies called Shadupakrama. Rukshana is one among them which can be used as both Bahiparimarjana and Antahparimarjana chikitsa. With Rukshana therapy, the body’s oily, sticky, fatty constituents are dried up and reduced. In this case series, three cases related to spinal pathology, especially cervical and lumbar spondylosis were successfully treated by incorporating the principle of Rukshana. Initially, the condition was visualized as Kaphavruta Vata/Vataanubandha Kapha. Hence the first line of treatment should be Kaphavatahara.  Apart from these there is the involvement of Ama in the Samprapthi and considering all these factors internally Rukshana was attained via oral medications and externally by Rukshana upakrama. After the Rukshana therapy patient shows marked improvement, assessments were recorded by comparing the grade of pain, joint tenderness, and range of motion before and after treatment. Notable changes are evidence that the Ayurvedic way of approach to treating spinal disorders is effective and successful. After Rukshana karma, Snigdha bahya karma was adopted along with some internal medications

Need-Based Apatarpana (Depleting) and Santarpana (Nourishing) Interventions in Managing Prameha with special reference to Type 2 Diabetes Mellitus

Prameha is a disease with different pathological conditions as per Ayurveda, comparable to Type 2 Diabetes mellitus. The main line of therapeutic intervention for Prameha, a disease due to over-nourishment, is Apatarpana (depleting regimens of Ayurveda to reduce the bulk of body tissues, particularly Meda and Mamsa dhatu in the present context). As a general principle of Ayurveda diagnosis, a disease is dynamic and changes its status and presentation with time, diet, and interventions. Complementing this, each therapeutic intervention is defined with deficit, optimum, and excess use features. Administering the intervention less than or beyond the requirement may harm the individual, resulting in hampered structure and/or function of other body components. In the present review, we have attempted to put forth this principle of need-based Apatarpana and Santarpana (bulk/strength promoting therapies of Ayurveda) interventions, in managing Prameha with special reference to Type 2 Diabetes Mellitus

Role of Uttarabasti in Neurogenic Urinary Incontinence

Neurogenic bladder refers to dysfunction of the urinary bladder arising from internal or external trauma, disease, or injury of the central, autonomic or somatic nervous system in the control of micturition. Depending on the nerves involved and the nature of the damage, bladder becomes either overactive or underactive and this usually presents clinically as urinary incontinence or retention of urine. Urinary Incontinence (UI) is a hygienic problem and is one of the troublesome, important cause of morbidity and impairment of quality of life, in both men and women. It may lead to recurrent UTI and ascending infections which affect the functioning of kidney. Deranged function of Vatadosha especially Apanavata along with Pranavata and Vyanavata are the main culprits of neurogenic bladder. Vitiated Doshas cause Mootravahasrotodushti and Atipravritti of mootra. This case study discusses the effect of Mootramarga uttarabasti in reducing the signs and symptoms of neurogenic urinary incontinence and thereby improving the quality of life. A 66 year old male patient was admitted with weakness in left upper and lower limbs, slurred speech, and difficulty in controlling micturition since 5 months. He was a diagnosed case of stroke on the basis of a brain computed tomography scan. During the course of management, Uttarabasti was administered for 8 days with Dhanwantarataila and Balamoolakashaya alternatively. The intervention resulted in reducing the symptoms of neurogenic urinary incontinence as evidenced by the reduction in ICIQ-UI -SF score. It was observed that the overall impact of the disease was reduced and quality of life improved with the help of King’s Health Questionnaire (KHQ)

Ayurvedic Management of Pemphigus Vegetans

Pemphigus vegetans is a group of autoimmune disorder characterized by mucocutaneous bullae or pustules that erode to form hypertrophic papillated plaques that predominantly involve the scalp, and the face. It is the rarest variant of pemphigus vulgaris representing about 1-2% of all pemphigus. It may be correlated with Kardama visarpa in Ayurveda. The contemporary management of pemphigus is by systemic steroids. This case report of a 38 year old, male patient diagnosed with Pemphigus vegetans who presented with pustular lesions with foul smell, reddish spots with hypertrophic papillated lesions on scalp, itching and burning sensation over various body parts especially on upper parts since 20 years. He was treated with both Samana as well as Sodhana therapies for about 1 month. This condition was assessed using Pemphigus diseases area index. After treatment there was a significant reduction in the score. Moreover no new lesions were formed suggesting non progression of the diseases

Determination of Polyphenolic Compounds Present in Guduchyadi Kashaya Using Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

The utilization of various contemporary analytical methods has become indispensable when it comes to assessing polyherbal Ayurvedic formulations, aiming to ensure their quality, safety, and effectiveness. Quality control of herbal medicines involve analytical evaluation using instrumental techniques such as TLC, HPTLC, HPLC, GC-MS, LC-MS and spectrophotometer etc. Among them Liquid Chromatography with tandem Mass Spectrometry (LC-MS/MS) is a powerful hyphenated analytical technique that combines the separating power of liquid chromatography with the mass analysis capabilities of mass spectrometry. Generally, its application is oriented towards the specific detection and potential identification of chemicals in a complex mixture. Polyphenolic compounds are usually referred to as a diverse group of naturally occurring compounds containing multiple phenolic functionalities. The anti-inflammatory, anti-aging, antiproliferative, and antioxidant like biological properties of phenolic compounds have been described in several studies. This research study was taken to analyse polyphenolic compounds in Guduchyadi kashaya by LC-MS/MS. Phenolic compounds are abundant in the ingredients of Guduchyadi kashaya, as evidenced by previous studies. So, to determine the polyphenolic contents of Guduchyadi kashaya, this study was conducted. The quantification of the polyphenols was carried out on Shimadzu Shim Pack GISS C18 column with .1%formic acid as mobile phase. A total of 28 polyphenolic compounds were analysed, and 24 of these compounds were found to be present in Guduchyadi kashaya. The results showed that the phenolic compounds present in the ingredients were also present in the formulation in high abundance