International Journal of Ayurveda and Pharma Research
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    Daivavyapashraya Chikitsa- A Preventive Strategy to Deal Maternal Stress

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    Maternal stress is a potential risk factor for the onset of neurodevelopmental disorders. These days, prenatal check-ups just look at women's physical health concerns. It is crucial to remember that a variety of stress, anxiety, and depressive symptoms, such as a strained relationship with one's spouse, can also have an impact on fetal development, in addition to diagnosable illnesses. It is very well highlighted in Ayurveda with the concept of Satva Vaisheshyakara Bhaavas, which says that, the psychological makeup of the offspring is influenced by various factors, such as the mother's mental health and what she hears, while she is pregnant. Through Mantra, Mani, Mangala, Bali, Homa, Upavasa and other healing techniques, Daivavyapashraya Chikitsa is an Ayurvedic therapy method, that promotes spiritual health and helps manage mental stress by dispelling negativity and fear and replacing it with a sense of optimism and control. Additionally, this Chikitsa has several logical traits that are consistent with the Theory of Cognitive Adaptation, which holds that, people create positive delusions as a defensive mechanism to shield their mental health from outside threats. With a scientific justification, this article seeks to highlight the potential advantages of Daivavyapashraya Chikitsa in lowering maternal stress

    Conceptual Study of Shatkriyakala in Shuskashipaka (Dry Eye Syndrome)

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    Shushkakshipaka is considered as a Sarvakshi roga by Ayurveda acharyas. Among different Acharyas there is difference in opinion about the Dosha predominance of the disease. According to Susruth Acharya it is a Vataja disease; but Vagbhata describes it as a Vatapitta entity. Vata, Pitta and Rakta play major roles in the pathogenesis of Sushkakshipaka. The term Kriyakala refers to the progress of the disease, which helps to determine the treatment modalities to be given to make the Doshas in equilibrium. The Kriya Kala explained by Susrutha is having six stages, consider as Shadkriyakala. Here is an attempt to explain Shushkakshipaka in terms of Shadkriyakala so that one can understand the stage of the disease and decide the treatment to be given

    Ayurvedic Management of STXBP1 Encephalopathy with West Syndrome - A Case Report

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    Developmental delay, intellectual disability, and epilepsy are hallmark features of STXBP1 encephalopathy. This condition is often associated with West syndrome, characterized by intractable epilepsy, developmental regression, and hypsarrhythmia on EEG. Even though timely intervention is crucial, Conventional medical systems lag behind to tackle the developmental regression and to gain control over the intractable epilepsy even with multiple anti epileptic drugs (AEDs). This is a case of a 7-year-old girl with an STXBP1 mutation, clinically diagnosed with West syndrome. She presented to the Kaumarabhritya OPD with significant developmental issues, including inability to sit without support, difficulty rising from a lying position, tremors, poor coordination, truncal ataxia, impaired speech, cognitive deficits, socialization issues, and intractable epilepsy. Ayurvedic management strategy was designed incorporating treatment principles of Apasmara (seizures), Unmada (insanity), Vatavyadhi (Vata disorders), and Sirakampa (head tremors), as an adjunct to ongoing AED regimen. Remarkable improvements were observed in motor, social, and language domains in a period of 4 months. Treatment efficacy was assessed using the Hague seizure severity scale, (improved from 24 to 49) and Gross Motor Function Measure score (increased from 18% to 30%). Receptive language age advanced from 0-1 month to 7-8 months, and expressive language age improved from 0-1 month to 10-12 months. Vineland Social Maturity Scale score improved from 3.5 to 8, and Indian Scale for Assessment of Autism score decreased from 130 to 105. This case report highlights the efficacy of Ayurvedic interventions in curtailing intractable epilepsy, arresting the neuronal regression and triggering the brain growth velocity

    Assessing the Effect of Shodhana (Purification) Process by Triphala Decoction on Shilajit Using High Performance Thin Layer Chromatography

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    Standardization of Shodhit Shilajit is a major challenge. Objective: Objective of the present study was to assessing the effect of Shodhana purification process on Shilajit as well as assessing the difference in fingerprint of raw Shilajit and Shodhit Shilajit by HPTLC and physicochemical tests. Methods: The standardization parameters such as appearance, identification of active marker compound Gallic acid and Fingerprint comparison by HPTLC, Physicochemical test parameters like loss on drying, pH value, ash value, water soluble extractive, ethanol soluble extractive and assay of humic acid and fulvic acid were evaluated during the study. Chromatographic separation was achieved by using Toluene: Ethyl acetate: Formic acid (5.0:4.0:1.0 v/v/v) as mobile phase followed by comparing the Rf values. Results: The presence of active marker compound gallic acid in Shodhit Shilajit was confirmed by comparing the Rf value with standard. HPTLC fingerprint also confirmed that constituents from raw Shilajit transferring to the Shodhit Shilajit after the process of Shodhana. Total Ash value and Acid insoluble ash value reduced from 52.95% to 21.67% and 2.35% to 0.39% respectively while Water soluble extractive value increased from 59.33% to 72.13% after Shodhana process. There is also an increase in percentages of humic acid and fulvic acid from 7.10% to 8.23% and 36.91% to 50.12 % in Shodhit Shilajit. Conclusion: All these results showed the significance and effectiveness of Shodhana process in reducing the impurities and ultimately enhancing the therapeutic activity of Shodhit Shilajit. These evaluation parameters can be used for the standardization of Shodhit Shilajit and also can be routinely employed for analysis in Quality Control Lab

    Ayurvedic Management of Dushta Vrana (Varicose Ulcer) with Dashanga Lepa

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    A wound, also known as a Vrana, is a condition where the body's tissues are damaged in a specific way, and after repair, the tissues become discolored, resulting in a permanent scar. Varicose ulcers are caused by persistent venous occlusion. A varicose leg ulcer occurs when blood recirculates through venous valves due to ischemia in the leg's vascular supply, caused by this insufficiency. Ignoring these lesions could lead to gangrene and infection. According to Ayurveda, varicose ulcers are associated with 'Sira Janya Dusta Vrana.' In the medical field, "Lepa" can be described as a therapeutic approach where medications are applied externally to alleviate pain, reduce inflammation, or speed up recovery. This case report on varicose ulcers includes the patient's complete medical history, necessary laboratory tests, and clinical and physical examinations. The patient undergoes daily dressings on an OPD basis and is treated with various internal medications along with external procedures like the application of Lepa. After the administration of Lepa, the wound healed, and other symptoms improved significantly

    Yashadamritamalaharam Application in the Management of Parikarthika - A Comprehensive Analytical Review

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    Parikartika is one among the anorectal diseases, which can be correlated with fissure in ano in the contemporary medicine. Parikartika is a disease condition rather than a single entity disease, which is usually triggered by other factors as per Ayurveda classics. It is usually described as a very painful condition which mostly affects the quality living. The disease pathology should be analyzed, studied and appropriate therapeutic measures should be advised to tackle and prevent the recurrence. There are many therapeutic methods available today for the treatment of Parikartika both in modern and Ayurveda. Modern methods are no replace oral pain medications, topical ointments, botulin injections surgical interventions etc. These have usually side effects and cause inconvenience to the patients. Ayurvedic preparations are also very effective, out of which a convenient, patient friendly easy method must be chosen. Yashadamrita malahara is a Malahara preparation from classical rasa text Rasatarangini which has wound healing properties which can be applied as an ointment or as Pichu. Aims and Objectives: This is an in-depth review analysis of Parikartika samprapti and the effect of Yashadamrita malahara in the management of the disease. Materials and methods: An attempt has been made to analyze the Samprapti ghatakas of Parikartika and the pharmacological actions of Yashadamrita malahara, and to explain the probable mode of action of the drug in the disease. Discussion and conclusion: Evaluation of the effect of Yashadamrita malahara and its therapeutic benefits in Parikartika by its mode of action

    Management of Rigidity Dominant Parkinson’s Disease Through Ayurvedic Protocol

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    Parkinson's Disease (PD) is a disease with insidious onset and slow progression. It is a neurologic condition that causes motor manifestations namely, bradykinesia, rigidity, resting tremor, postural instability and non-motor symptoms such as depression and dementia. The modern treatment provides some symptomatic relief but any proven means for slowing the progression have not been found yet. This case is of a 64-year-old male patient who presented with complaints of slowness in daily activities, difficulty in raising left upper arm along with heaviness, tremors in both hands, difficulty in speech and movement for 3 years. Complaints were increasing progressively hindering his routine activities. He underwent our IP management for 60 days with follow-up after every 20 days. In every follow-up, the patient reported significant relief in his symptoms and after two months, he was able to perform his routine activities without any help

    Varieties of Classical Drug Kadamba

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    Kadamb an indigenous plant described in classical texts of Ayurved has a wide range of therapeutic potential. In Charak Samhita, it has been classified in the group of drugs indicated in the management of pain (Vednasthapan Mahakashya). Among various indications, it has been reported to be used in the treatment of vitiated semen, as an astringent in healing of fractured wounds, hemorrhagic conditions, dyslipidaemia, diseases of female genital tract, as complexion promoting and alexipharmic. In classical texts, at least four varieties of Kadamb have been described. There has always been some controversy regarding botanical identity of different varieties of Kadamb described in classical texts. Present paper is a serious attempt towards establishment of botanical identities of different types of Kadamb described in classical text of Ayurved on the basis of exploration of literature substantiated by observations of field survey

    Elevating the Inner-Consciousness “Third-Eye” Through “Vedic Manas Yoga” Practice

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    ‘Third-Eye Chakra’, also known as ‘Ajna Chakra’ in Sanskrit, is the sixth of the body's seven major Chakras. It is also known as the "perception center" and, said to be the seat of soul and the portal to higher awareness. It is essential for achieving greater awareness and serves as the focus of concentration during Asana or meditation practices. Ajna Chakra corresponds to the hypothalamus, pituitary gland, and pineal gland, as well as the eyes, ears, and nose in the physical body. Vedic manas yoga is a holistic approach to yoga that integrates concepts from the Vedas, ancient Indian literature, with practices that attempt to balance the mind, body, and spirit. This study was conducted to develop the inner consciousness and awake the dormant powers of individual participants using Vedic manas yoga. In this observational study, a total 30 physically and mentally healthy subject aged in between 5 to 15 years of both gender from Patanjali Gurukulam, Haridwar, were included. The Pre- and Post-treatment SF-36 scores were statistically evaluated using paired t-test. There was a significant difference (p<0.5) observed in mean scores of Pre-program and Post-program scores of SF-36 after three days programmed interventions against psycho-social, spiritual and emotional development of subjects. The paired t-test revealed a significant score having p<0.05 for pre-program and post-program questionnaire responses. The maximum improvement was recorded to be 22% with overall third-eye activation. Vedic manas yoga practice has shown significant improvement in SF-36 among subjects participating in this study and, further studies are recommended to awaken the inner consciousness and align the energies of body, mind and spirit

    Effect of Guggulu Tiktakam Kashayam in Uterine Fibroid

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    The most common benign uterine tumours affecting women in reproductive and perimenopausal stages are fibroids or leiomyomas. There is strong evidence that estrogen and progesterone promote the growth of fibroids, despite the fact that their exact aetiology is still unclear. This is because fibroids seldom arise before menarche and retreat after menopause. The most prevalent reason for hysterectomy is fibroids. Menorrhagia, polymenorrhoea, metrorrhagia, intermenstrual bleeding, infertility, repeated abortions, pain and pressure feelings, abdominal lumps, and vaginal discharge are a few of the symptoms they exhibit clinically. In Ayurveda there is no exact correlation for uterine fibroid. Fibroids can be considered as Mamsa Grandhis, one among the Grandhis described by Charaka and Vagbhata. They increase the surface area of the endometrial tissue in the uterus when present, causing excessive bleeding, pressure feelings, dysmenorrhea, and even infertility. Vata-Kapha predominant Tridoshas have a role in the aetiology of the Granthi Roga, necessitating the use of Vata-kaphahara medicines. As Granthi can also be caused by Mandagni, in Granthi chikitsa we can make use of Dravyas that are Deepana pachana. According to Acharya Susrutha, Sopha Chikitsa is included in the Apakwa Granthi chikitsa. In Mamsa granthi chikitsa, Shothagna, Lekhana, Chedhana, and Vatanulomana dravyas may be utilised. Asrigdara chikitsa and Raktapitta chiktsa can be used to treat fibroids when heavy, prolonged menstrual cycles are present. A 38 year old lady was presented with complaints of heavy, prolonged bleeding during menstruation along with lower abdomen pain. On USG she was diagnosed with uterine fibroids. Guggulu tikitakam kashayam was given for 3 months and after follow up symptoms were evaluated. She was relieved from prolonged heavy bleeding during menstruation and lower abdomen pain. From this case report, it is evident that Guggulu tiktakam kashayam is effective in uterine fibroid

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