11 research outputs found
Multi-messenger observations of a binary neutron star merger
- Author
- Aab A
- Aartsen MG
- Abbott BP
- Abbott R
- Abbott TD
- Abbott TMC
- Abdalla H
- Abe F
- Abeysekara AU
- Abramo LR
- Abramowski A
- Abreu P
- Acernese F
- Acero F
- Ackermann M
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- Ackley K
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- Affeldt C
- Afrough M
- Agarwal B
- Agathos M
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- Aggarwal N
- Aglietta M
- Agliozzo C
- Agudo I
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- Aguilar JA
- Aharonian F
- Ahlers M
- Ahrens M
- Aiello L
- Ain A
- Ajith P
- Akras S
- Al Samarai I
- Albert A
- Albert A
- Albuquerque IFM
- Albury JM
- Alcaniz JS
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- Alfaro R
- Alighieri S Di Serego
- Allam S
- Allekotte I
- Allen B
- Allen G
- Allison J
- Allison JR
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- Altmann D
- Alvarez C
- Alvarez JD
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- Aoki W
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- Arakawa M
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- Arcavi I
- Arceo R
- Ardid M
- Areeda JS
- Aresu G
- Argan A
- Argelles C
- Arnaud N
- Array LWA Long Wavelength
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- Arrieta M
- Arsene N
- Arteaga-Velzquez JC
- Artola R
- Arun KG
- Asakura Y
- Asaoka Y
- Ascenzi S
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- Ashton G
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- Atwood WB
- Aubert J-J
- Aubert P
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- Peiffer P
- Peixoto CJ Todero
- Pekeur NW
- Pekowsky L
- Pelayo R
- Pele A
- Pellegrino C
- Pelletier G
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- Penacchioni AV
- Penn S
- Penuela T
- Pepper JA
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- Perennes C
- Perez CJ
- Perez-Perez EG
- Perley DA
- Perlin M
- Perreca A
- Perri LM
- Perri M
- Perrina C
- Perrodin D
- Perrone L
- Pescalli A
- Pesce-Rollins M
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- Petrera S
- Petrucci P-O
- Peyaud B
- Pfeiffer HP
- Phelps M
- Phlhofer G
- Phuntsok J
- Pian E
- Piano G
- Piattelli P
- Piccinni OJ
- Pichot M
- Picozza P
- Piel Q
- Pieloth D
- Piergiovanni F
- Pierog T
- Pierro V
- Pignata G
- Pike S
- Pilia M
- Pillant G
- Pimenta M
- Pinard L
- Pinat E
- Pinto IM
- Piotrowski LW
- Piran T
- Piran T
- Piranomonte S
- Pirello M
- Piro AL
- Piro L
- Piron F
- Pirronello V
- Pisanu T
- Pita S
- Pitkin M
- Pittori C
- Placco VM
- Platino M
- Plazas AA
- Plum M
- Podesta F
- Podesta RC
- Podsiadlowski P
- Poe M
- Poggiani R
- Poh J
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- Pollmann A Obertacke
- Poolakkil S
- Poon H
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- Popolizio P
- Poppi S
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- Porter EK
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- Possenti A
- Post A
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- Powell J
- Pozanenko AS
- Poznanski D
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- Prado RR
- Prasad J
- Pratt JWW
- Pratten G
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- Prestegard T
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- Price PB
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- Principe G
- Principe M
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- Privitera P
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- Prochaska JX
- Prodi GA
- Prokhorov D
- Prokhorov LG
- Prokoph H
- Prouza M
- Prrer M
- Przybylski GT
- Pulone L
- Pumo ML
- Punch M
- Puncken O
- Punturo M
- Puppo P
- Qi H
- Qi H
- Qu JL
- Quataert E
- Quel EJ
- Querchfeld S
- Querel R
- Quetschke V
- Quimby RM
- Quinn L
- Quinn S
- Quinones C
- Quintero EA
- Quirrenbach A
- Quispe ID Vergara
- Quitzow-James R
- Raab C
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- Rabeling DS
- Rabus M
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- Raffai P
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- Raja S
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- Rameez M
- Ramirez KE
- Ramirez-Ruiz E
- Ramos-Buades A
- Ramos-Pollan R
- Rana J
- Rando R
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- Rappoldi A
- RATIR RIMAS
- Rau A
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- Rauth R
- Ravignani D
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- Raymond V
- Razza A
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- Razzaque S
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- Rdiger A
- Rea IC
- Read J
- Rebolo R
- Regimbau T
- Rei L
- Reichart DE
- Reid S
- Reimann R
- Reimer A
- Reimer A
- Reimer O
- Reimer O
- Reitze DH
- Relethford B
- Relich M
- Ren W
- Ren Z
- Renaud M
- Renzi V
- Reposeur T
- Resconi E
- Resmi L
- Rest A
- Reva IV
- Reyes R De Los
- Reyes SD
- Reynolds T
- Rho CD
- Rhode W
- Ribeiro T
- Ricci F
- Ricci R
- Ricciarini S
- Riccobene G
- Richman M
- Ricker PM
- Ridden-Harper R
- Ridky J
- Rieger F
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- Riehn F
- Righini S
- Riguccini L
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- Rinchiuso L
- Rios-Lopez E
- Risse M
- Ristori P
- Rivera A Ramirez
- Riviere C
- Rizi V
- Rizzo M
- Roberts OJ
- Robertson NA
- Robertson S
- Robie R
- Robinet F
- Rocchi A
- Rochester LS
- Rodi J
- Rodriguez H
- Rojas D Avila
- Rojas-Bravo C
- Rojo J Rodriguez
- Rol E
- Rolland L
- Rollins JG
- Roma VJ
- Romano R
- Romel CL
- Romer AK
- Romero M Dominguez
- Romie JH
- Romoli C
- Roncoroni MJ
- Rongen M
- Roodman A
- Roques J-P
- Rosa-Gonzlez D
- Rosell A Carnero
- Rosenberg M
- Rosetti S
- Rosinska D
- Ross MP
- Rossi A
- Rosswog S
- Rosswog S
- Roth M
- Rott C
- Roulet E
- Rovero AC
- Rowan S
- Rowell G
- Rowlinson A
- Rowlinson A
- Roy R
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- Rudak B
- Ruehl P
- Ruggi P
- Ruhe T
- Ruiter AJ
- Ruiz R Gracia
- Ruiz-Velasco E
- Rulten CB
- Rumyantsev VV
- Rusu F
- Rutins G
- Ryan K
- Rybicki KA
- Ryckbosch D
- Rykoff ES
- Rysewyk D
- Saba A
- Sachdev S
- Sadecki T
- Sadeghian L
- Sadler EM
- Sadler EM
- Saffe C
- Saffi SJ
- Saftoiu A
- Sahakian V
- Sai N
- Saito S
- Saito T
- Saito Y
- Sakamaki A
- Sakamoto T
- Sakellariadou M
- Sako M
- Sako S
- Salafia OS
- Salamida F
- Salazar H
- Salazar H
- Salconi L
- Saldaa M
- Saleem M
- Saleh A
- Salemi F
- Salina G
- Salmon L
- Salvadori I
- Salvaterra R
- Samajdar A
- Sammut L
- Sampedro L
- Sampson LM
- Samtleben DFE
- Sanchez B
- Sanchez DA
- Sanchez E
- Sanchez EJ
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- Sanchez LE
- Sanchez-Losa A
- Sanchez-Lucas P
- Sanchez-Ramirez R
- Sanchis-Gual N
- Sand DJ
- Sandberg V
- Sanders JR
- Sandoval A
- Sandrock A
- Sandroos J
- Sanguineti M
- Sansom EK
- Santander M
- Santangelo A
- Santos E
- Santos EM
- Sapienza P
- Sarazin F
- Sarkar S
- Sarkar S
- Sarmento R
- Sarmiento-Cano C
- Sasaki M
- Sasaki R
- Sassolas B
- Satalecka K
- Sathyaprakash BS
- Sato R
- Saulson PR
- Sauseda M
- Sauter O
- Savage RL
- Savchenko V
- Sawadsky A
- Sbarufatti B
- Scalzo RA
- Scarpine V
- Schady P
- Schale P
- Schauer M
- Scheel M
- Scherini V
- Scheuer J
- Schieler H
- Schimp M
- Schindler R
- Schipani P
- Schlegel DJ
- Schlickeiser R
- Schlunder P
- Schmalz SE
- Schmidt BP
- Schmidt D
- Schmidt J
- Schmidt P
- Schmidt T
- Schnabel R
- Schneider A
- Schneider M
- Schneiter M
- Schoenell W
- Schoenen S
- Schofield RMS
- Scholten O
- Schonbeck A
- Schoneberg S
- Schoorlemmer H
- Schovnek P
- Schreiber E
- Schroder FG
- Schroder S
- Schroder SL
- Schssler F
- Schubnell M
- Schuette D
- Schulte BW
- Schultz ASB
- Schulz A
- Schulz A
- Schulze S
- Schumacher J
- Schumacher L
- Schutz BF
- Schwalbe SG
- Schwanke U
- Schwemmer S
- Schweyer T
- Sciutto SJ
- Scolnic D
- Scott J
- Scott SM
- Secco LF
- Seckel D
- Seglar-Arroyo M
- Segreto A
- Seidel E
- Seitenzahl IR
- Sekiguchi Y
- Sellers D
- Selsing J
- Sengupta AS
- Sentenac D
- Sequino V
- Sergeev A
- Sergienko Yu P
- Serino M
- Serra G
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- Serrau M
- Settimo M
- Seunarine S
- Sevilla-Noarbe I
- Seyffert AS
- Sgro C
- Shaddock DA
- Shadkam A
- Shaffer TJ
- Shafi N
- Shah AA
- Shahriar MS
- Shaner MB
- Shang Z
- Shannon RM
- Shao L
- Shapiro B
- Shappee BJ
- Shara MM
- Sharma I
- Sharp RG
- Shawhan P
- Sheldon E
- Shellard RC
- Sheperd A
- Shidatsu M
- Shilon I
- Shimizu Y
- Shimomukai R
- Shingles LJ
- Shiningayamwe K
- Shoemaker DH
- Shoemaker DM
- Shulevski A
- Siebert MR
- Siegel MH
- Sieger C
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- Siemens X
- Sieniawska M
- Sigg D
- Sigl G
- Silli G
- Silva AD
- Sim SA
- Simon JD
- Simonetti JH
- Simoni R
- Singer LP
- Singh A
- Singhal A
- Sinnis G
- Sintes AM
- Siskind EJ
- Slagmolen BJJ
- Slzer T
- Smartt SJ
- Smida R
- Smirnov OM
- Smith AJ
- Smith B
- Smith JR
- Smith KW
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- Smith M
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- Snow GR
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- Sobreira F
- Sodre L
- Soedingrekso J
- Soffitta P
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- Sollerman J
- Sollerman J
- Somala S
- Sommers P
- Son EJ
- Song LM
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- Sonnenberg JA
- Sonntag S
- Sorazu B
- Soriano JF
- Sorrentino F
- Souradeep T
- Spada F
- Spandre G
- Spanier F
- Spencer AP
- Spera M
- Spiczak GM
- Spiering C
- Spir-Jacob M
- Springer RW
- Spurio M
- Squartini R
- Srivastava AK
- Staats K
- Stachurska J
- Staff J
- Stagni M
- Stalder B
- Staley A
- Stamatikos M
- Stamerra A
- Stanbro M
- Stanca D
- Stanev T
- Stanic S
- Stanway ER
- Starck M
- Starling RLC
- Stasielak J
- Stasik A
- Stassi P
- Stawarz L
- Stebbins A
- Steeghs DTH
- Steele I
- Steele K
- Steenkamp R
- Stegmann C
- Steinke M
- Steinlechner J
- Steinlechner S
- Steinmeyer D
- Stella L
- Steppa C
- Stettner J
- Steuer A
- Stevenson SP
- Stewart AJ
- Stezelberger T
- Stokstad RG
- Stolarczyk Th
- Stolpovskiy M
- Stone R
- Stops DJ
- Stosl A
- Strafella F
- Strain KA
- Stratta G
- Streich A
- Strigin SE
- Strotjohann NL
- Strunk A
- Stubbs CW
- Sturani R
- Stuttard T
- Stuver AL
- Suarez F
- Suarez-Duran M
- Suchyta E
- Sudholz T
- Sugawara Y
- Sugita S
- Sugizaki M
- Sullivan GW
- Sullivan M
- Sumi T
- Summerscales TZ
- Sun L
- Sun L
- Sun T
- Sunil S
- Suntzeff NB
- Sunyaev R
- Suomijarvi T
- Supanitsky AD
- Supik J
- Surajbali P
- Surcis G
- Suresh J
- Sushch I
- Suson DJ
- Sutherland M
- Sutton PJ
- Svinkin DS
- Swain J
- Swanson MEC
- Swinkels BL
- Szadkowski Z
- Szczepanczyk MJ
- Szegedi H
- Szomoru A
- Taboada A
- Taboada I
- Taborda OA
- Tacca M
- Tachibana Y
- Taddia F
- Tagliaferri G
- Tait SC
- Taiuti M
- Tajitsu A
- Takahashi I
- Takahashi J
- Takahashi M
- Takahashi T
- Takao Y
- Takayama M
- Talbot C
- Talukder D
- Tamura T
- Tamura Y
- Tan Y
- Tanaka I
- Tanaka M
- Tanaka Y
- Tanimoto A
- Tanner DB
- Tanvir NR
- Tao C
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- Tao WH
- Taracchini A
- Tarle G
- Tartaglia L
- Tasson JD
- Tatar J
- Taubenberger S
- Tavani M
- Tavernet J-P
- Tavernier T
- Tayalati Y
- Taylor AM
- Taylor GB
- Taylor JA
- Taylor R
- Team AGILE
- Team Euro VLBI
- Team MAXI
- Team The 1M2H
- Telescope ATCA Australia
- Telescope Fermi Large Area
- Telescope Nordic Optical
- Tello JC
- Telluride AstroSat Cadmium Zinc
- Tenholt F
- Ter Veen S
- Ter-Antonyan S
- Terai T
- Terliuk A
- Terreran G
- Terrier R
- Tesic G
- Testa V
- Tewari SV
- Thayer JB
- Thayer JG
- Theeg T
- Thene CC
- Thierry P
- Thierry P
- Thies F
- Thomas EG
- Thomas M
- Thomas P
- Thomas RC
- Thompson DJ
- Thorne KA
- Thorne KS
- Thrane E
- Tibaldo L
- Tibaldo L
- Tibolla O
- Tilav S
- Timmermans C
- Tingay SJ
- Tiwari S
- Tiwari V
- Tiziani D
- Tjus J Becker
- Tjus J Becker
- Tlatov AG
- Tluczykont M
- Toale PA
- Tobin MN
- Tohuvavohu A
- Tokmakov KV
- Toland K
- Tollefson K
- Toma K
- Tomankova L
- Tomasella L
- Tome B
- Tomida H
- Tominaga N
- Tonelli M
- Tonnis C
- Tonry J
- Torii S
- Tornasi Z
- Tornatore M
- Torres DF
- Torres I
- Torres-Flores S
- Torres-Forn A
- Torresi E
- Torrie CI
- Toscano S
- Tosi D
- Towner MC
- Toyr D
- Tpai M
- Travasso F
- Travnicek P
- Traylor G
- Trichard C
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- Trinastic J
- Tringali MC
- Trini M
- Tristram PJ
- Trois A
- Troja E
- Troja E
- Trott CM
- Trovato A
- Troxel MA
- Trozzo L
- Tsai J
- Tsang KW
- Tse M
- Tselengidou M
- Tsirou M
- Tso R
- Tsuboi Y
- Tsuji N
- Tsukada L
- Tsuna D
- Tsunemi H
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- Tungalag N
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- Turpin D
- Turpin D
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- Ty B
- Tyurina NV
- Ubertini P
- Uchiyama Y
- Ueda Y
- Uemura M
- Ueno K
- Ueno S
- Ugolini D
- Ukwatta TN
- Ulaczyk K
- Ulanov MV
- Ulloa N
- Ulrich R
- Unger E
- Unger M
- Univ Chandra Team McGill
- Univ Texas Tech
- Universe High Time Resolution
- Unnikrishnan CS
- Urban AL
- Urban M
- Ursi A
- Usman SA
- Usner M
- Utsumi Y
- Vacca V
- Vadawale SV
- Vahlbruch H
- Vaisanen P
- Vajente G
- Valdes G
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- Valio I
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- Van der Walt DJ
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- Vander-Hyde DC
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- Vergani D
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- Verkindt D
- Verrecchia F
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- Vibhute A
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- Viets AD
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- Vink J
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- Vitale PF Gomez
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- Vivolo D
- Vizzoca A
- Vladimirov VV
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- Vo T
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- Vogel E
- Voisin F
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- Vorobiov S
- Vorvick C
- Vos J
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- Wainscoat RJ
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- Walz D
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- Wave GRAWITA GRAvitational
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- Weiland H
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- Wessel EK
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- Wiebusch CH
- Wiedenski M
- Wiencke L
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- Wiersema K
- Wierzcholska A
- Wijers RAMJ
- Wijers RAMJ
- Wilczynski H
- Wilken D
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- Williams PKG
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- Wilms J
- Wilson-Hodge CA
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- Worden J
- Woschnagg K
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- Wrochna G
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- Wundheiler B
- Wyrzykowski L
- Wysocki DM
- Xiao GC
- Xiao S
- Xiong SL
- Xu D
- Xu DL
- Xu H
- Xu XW
- Xu Y
- Xu Y
- Xu YP
- Yamada S
- Yamaguchi MS
- Yamamoto H
- Yamaoka K
- Yamaoka K
- Yamauchi M
- Yan L
- Yan LL
- Yancey CC
- Yanez JP
- Yang J
- Yang J
- Yang JW
- Yang L
- Yang L
- Yang R
- Yang S
- Yang S
- Yang YJ
- Yanny B
- Yap MJ
- Yapici T
- Yaron O
- Yasuda N
- Yatabe F
- Yatsu Y
- Yazback M
- Yock PC
- Yodh G
- Yodh GB
- Yoneyama T
- Yoon Y
- Yoshida A
- Yoshida M
- Yoshida S
- Yoshii T
- Young DR
- Younk PW
- Yu Hang
- Yu Haocun
- Yu P-C
- Yuan T
- Yuan X
- Yurkov VV
- Yushkov A
- Yvert M
- Zaborov D
- Zacharias M
- Zadrozny A
- Zadrozny A
- Zaharijas G
- Zaltzman M
- Zanin R
- Zanolin M
- Zaremba M
- Zarnecki AF
- Zas E
- Zavrtanik D
- Zavrtanik M
- Zdziarski AA
- Zech A
- Zefi F
- Zelenova T
- Zendri J-P
- Zenko T
- Zenteno A
- Zepeda A
- Zertuche L Magaa
- Zevin M
- Zhang AM
- Zhang B-B
- Zhang C
- Zhang CL
- Zhang CM
- Zhang F
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- Zhang HM
- Zhang J
- Zhang L
- Zhang M
- Zhang Q
- Zhang S
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- Zhang T
- Zhang W
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- Zhang Y
- Zhang Y
- Zhang Y
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- Zhang YF
- Zhang YJ
- Zhang Z
- Zhang ZL
- Zhao C
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- Zhao JL
- Zhao W
- Zhao XF
- Zheng SJ
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- Zhu SJ
- Zhu XJ
- Zhu Y
- Zhu YX
- Zhu Z
- Ziegler A
- Zimmerman AB
- Zimmermann B
- Zimnukhov DS
- Ziolkowski M
- Zoll M
- Zong Z
- Zorn J
- Zornoza JD
- Zou CL
- Zuccarello F
- Zucker ME
- Zuniga J
- Zweizig J
- Zywucka N
- Publication venue
- 'American Astronomical Society'
- Publication date
- 01/01/2017
- Field of study
On 2017 August 17 a binary neutron star coalescence candidate (later designated GW170817) with merger time 12:41:04 UTC was observed through gravitational waves by the Advanced LIGO and Advanced Virgo detectors. The Fermi Gamma-ray Burst Monitor independently detected a gamma-ray burst (GRB 170817A) with a time delay of ~1.7 s with respect to the merger time. From the gravitational-wave signal, the source was initially localized to a sky region of 31 deg2 at a luminosity distance of 40+8-8 Mpc and with component masses consistent with neutron stars. The component masses were later measured to be in the range 0.86 to 2.26 Mo. An extensive observing campaign was launched across the electromagnetic spectrum leading to the discovery of a bright optical transient (SSS17a, now with the IAU identification of AT 2017gfo) in NGC 4993 (at ~40 Mpc) less than 11 hours after the merger by the One- Meter, Two Hemisphere (1M2H) team using the 1 m Swope Telescope. The optical transient was independently detected by multiple teams within an hour. Subsequent observations targeted the object and its environment. Early ultraviolet observations revealed a blue transient that faded within 48 hours. Optical and infrared observations showed a redward evolution over ~10 days. Following early non-detections, X-ray and radio emission were discovered at the transientâs position ~9 and ~16 days, respectively, after the merger. Both the X-ray and radio emission likely arise from a physical process that is distinct from the one that generates the UV/optical/near-infrared emission. No ultra-high-energy gamma-rays and no neutrino candidates consistent with the source were found in follow-up searches. These observations support the hypothesis that GW170817 was produced by the merger of two neutron stars in NGC4993 followed by a short gamma-ray burst (GRB 170817A) and a kilonova/macronova powered by the radioactive decay of r-process nuclei synthesized in the ejecta
Multi-messenger Observations of a Binary Neutron Star Merger
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- Zucker M. E.
- Zweizig J.
- ZĂșñiga J.
- Publication venue
- 'American Astronomical Society'
- Publication date
- 28/10/2022
- Field of study
On 2017 August 17 a binary neutron star coalescence candidate (later
designated GW170817) with merger time 12:41:04 UTC was observed through
gravitational waves by the Advanced LIGO and Advanced Virgo detectors.
The Fermi Gamma-ray Burst Monitor independently detected a gamma-ray
burst (GRB 170817A) with a time delay of ⌠1.7 {{s}} with respect to
the merger time. From the gravitational-wave signal, the source was
initially localized to a sky region of 31 deg2 at a
luminosity distance of {40}-8+8 Mpc and with
component masses consistent with neutron stars. The component masses
were later measured to be in the range 0.86 to 2.26 {M}ÈŻ
. An extensive observing campaign was launched across the
electromagnetic spectrum leading to the discovery of a bright optical
transient (SSS17a, now with the IAU identification of AT 2017gfo) in NGC
4993 (at ⌠40 {{Mpc}}) less than 11 hours after the merger by the
One-Meter, Two Hemisphere (1M2H) team using the 1 m Swope Telescope. The
optical transient was independently detected by multiple teams within an
hour. Subsequent observations targeted the object and its environment.
Early ultraviolet observations revealed a blue transient that faded
within 48 hours. Optical and infrared observations showed a redward
evolution over âŒ10 days. Following early non-detections, X-ray and
radio emission were discovered at the transientâs position ⌠9
and ⌠16 days, respectively, after the merger. Both the X-ray and
radio emission likely arise from a physical process that is distinct
from the one that generates the UV/optical/near-infrared emission. No
ultra-high-energy gamma-rays and no neutrino candidates consistent with
the source were found in follow-up searches. These observations support
the hypothesis that GW170817 was produced by the merger of two neutron
stars in NGC 4993 followed by a short gamma-ray burst (GRB 170817A) and
a kilonova/macronova powered by the radioactive decay of r-process
nuclei synthesized in the ejecta.</p
Congenital transmission of Trypanosoma cruzi: an operational outline for detecting and treating infected infants in north-western Argentina
- Author
- Arcavi M
- Azogue E
- Bittencourt AL
- Bittencourt AL
- Chuit R
- Cura EN
- Elsa L. Segura
- Estela N. Cura
- Freilij H
- Freilij H
- Gabriela Garbarino
- Gurtler RE
- Hernandez-Matheson IM
- Instituto Nacional de Chagas
- Isolina Flores
- Juan F. Villalonga
- Liliana Tulian
- Lorca M
- Ministerio de Salud Publica y Medio Ambiente de la Nacion
- Ministerio de Salud y Accion Social de la Nacion
- Ministerio de Salud y Accion Social de la Nacion
- Moya P
- Moya PR
- Perez AC
- Reimer CB
- Reyes MB
- Ricardo E. Gurtler
- Roberto Chuit
- Russomando G
- Saleme A
- Schmunis GA
- Segura EL
- Segura EL
- Segura EL
- Sonia B. Blanco
- Streiger M
- Szarfman A
- Votta RA
- Zaidenberg M
- Publication venue
- 'Wiley'
- Publication date
- Field of study
Fertility, Gestation Outcome and Parasite Congenital Transmissibility in Mice Infected with TcI, TcII and TcVI Genotypes of Trypanosoma cruzi
- Author
- A el Bouhdidi
- A Falla
- A Mjihdi
- A Mjihdi
- A Rassi Jr
- AA Rodrigues
- AL Bittencourt
- B Vray
- B Zingales
- Barbara A. Burleigh
- C Bern
- C Diaz-Lujan
- C Truyens
- CA Hall
- CA Menezes
- Carine Truyens
- CR Marinho
- DA Pena
- DA Somerset
- E Hermann
- EA Moreno
- F del Puerto
- F Torrico
- F Torrico
- FC Oliveira
- GL Shaw
- H Id Boufker
- H Schenone
- H Werner
- H Werner
- HL Lenzi
- HO Davila
- HO Davila
- IM Hernandez-Matheson
- J Munoz
- JC Cross
- JM Burgos
- JM Bustamante
- JM Bustamante
- JR Coura
- JR Teruel
- KL Cummings
- KS Calabrese
- L Brutus
- LP Martins
- LR Siriano
- M Alarcon
- M Virreira
- M Virreira
- M Virreira
- MA Delgado
- MA Sala
- ME Solana
- ME Solana
- MP Cabeza
- MT Rivera
- Nicolas Coltel
- P Storni
- P Vacchina
- R Disko
- RA Lazarte
- RM Corrales
- RW de Cunio
- S Castanys
- S Cencig
- S Fernandez-Aguilar
- S Ortiz
- Sabrina Cencig
- SG Andrade
- SM Alkmim-Oliveira
- W Apt
- W Apt
- Y Carlier
- Y Carlier
- Y Carlier
- Y Carlier
- Y Jackson
- Yves Carlier
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 01/01/2013
- Field of study
This work aims to compare the effects of acute or chronic infections with the T. cruzi genotypes TcI (X10 strain), TcII (Y strain) and TcVI (Tulahuen strain) on fertility, gestation, pup growth and the possible vertical transmission of parasites in BALB/c mice. The occurrence of congenital infection was evaluated by microscopic examination of blood and/or qPCR on blood and heart in newborn pups and/or older offspring submitted to cyclophosphamide-induced immunosuppression in order to detect possible cryptic congenital infection. Altogether, the results show that: i) for the three strains tested, acute infection occurring after the embryo implantation in the uterus (parasite inoculation 4 days before mating), or close to delivery (parasite inoculation on day 13 of gestation), prevents or severely jeopardizes gestation outcome (inducing pup mortality and intra-uterine growth retardation); ii) for the three strains tested, gestation during chronic infection results in intra-uterine growth retardation, whereas re-inoculation of TcVI parasites during gestation in such chronically infected mice, in addition, strongly increases pup mortality; iii) congenital infection remains a rare consequence of infection (occurring in approximately 4% of living pups born to acutely infected dams); iv) PCR, detecting parasitic DNA and not living parasites, is not convenient to detect congenial infection close to delivery; v) transmission of parasites by breast milk is unlikely. This study should encourage further investigations using other parasite strains and genotypes to explore the role of virulence and other factors, as well as the mechanisms of such effects on gestation and on the establishment of congenital infection
Mapping the human genetic architecture of COVID-19
- Author
- Abdelrazik M.
- Abdullah T.
- Abe R.
- Abe S.
- Abecasis G. R.
- Abel L.
- Abernathy C.
- Abraheem A.
- Abul-Husn N. S.
- Acosta-Herrera M.
- Acquilini D.
- Adachi T.
- Adachi Y.
- Adams C.
- Adams K.
- Adanini O.
- Adeleye O.
- Adeniji K.
- Adra D.
- Afifi N.
- Afilalo J.
- Afilalo M.
- Afolabi D.
- Afrasiabi Z.
- Afset J. E.
- Agasou A.
- Aghemo A.
- Agranoff D.
- Agrawal S.
- Aguirre L. A.
- Agwuh K.
- Ahmad H. F.
- Ahmad N.
- Ahmed A.
- Ahmed C.
- Ahmed K. A.
- Ai M.
- Ail D.
- Akeroyd L.
- Akhtar M. N.
- Akhtar S.
- Akinkugbe O.
- Aksentijevich A.
- Al Thani A.
- Al-Muftah W.
- Al-Sarraj Y.
- Alarcon C.
- Alarcon-Riquelme M. E.
- Alasdair F.
- Alaverdian D.
- Alavere H.
- Albertos R.
- Albillos A.
- Albrecht W.
- Albrich W.
- Albrich W. C.
- Aldera E. L.
- Aldridge J.
- Alegria A.
- Alex B.
- Alexander P.
- Alfonso J.
- Algera A. G.
- Ali A.
- Ali I. A. M.
- Ali S.
- Aliberti S.
- Allan A.
- Allan E.
- Allan J.
- Alldis Z.
- Allen L.
- Allen S.
- Allibone S.
- Allison K. S.
- Allos R.
- Ally S. M.
- Almaden-Boyle C.
- Altabaibeh A.
- Altmuller J.
- Alvaro A.
- Amar D.
- Amin V.
- Amitrano S.
- Amiya S.
- Ampuero J.
- Anan R.
- Anania S.
- Anastasescu E.
- Anderson F.
- Anderson J.
- Anderson M.
- Anderson P.
- Anderson S.
- Anderson S.
- Anderson T.
- Ando A.
- Andolfo I.
- Andrade V.
- Andretta F.
- Andreucci E.
- Andrew A.
- Andrew B.
- Andrew G.
- Andrews E.
- Andrews S. J.
- Andrikopoulos P.
- Anedda F.
- Aneli S.
- Anemoli V.
- Angelini C.
- Angus B.
- Ann Belli M.
- Annis A.
- Antcliffe D.
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- Wu Y.
- Wulandari R.
- Wyllie D. H.
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- Xavier K.
- Xue X.
- Yadav A.
- Yagi K.
- Yamada M.
- Yamada Y.
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- Yasui Y.
- Yates B.
- Yatomi M.
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- Yengo L.
- Yermakovich D.
- Yi X.
- Yonekawa A.
- Yoon H.
- Yoon K. J.
- Yoshida K.
- Yoshida S.
- Yoshida S.
- Yoshida T.
- Yoshihara T.
- Yoshiya K.
- Yoshiyama T.
- Youlton N.
- Young P.
- Yun N.
- Zak A.
- Zaki A.
- Zambon M.
- Zamikula J.
- Zanella A.
- Zanella I.
- Zanelli G.
- Zara F.
- Zarate R.
- Zborowski A. C.
- Zeberg H.
- Zechner M.
- Zguro K.
- Zhai R.
- Zhang M.
- Zhao J. H.
- Zhen J.
- Zheng C.
- Zheng T.
- Zhou W.
- Zhu W.
- Zitter L.
- Zlatopolsky M.
- Zoller H.
- Zollner S.
- Zongo O.
- Zucchi P.
- Zyndorf M.
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2021
- Field of study
The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors have a role in the chance of exposure to SARS-CoV-2 and the severity of COVID-191,2, host genetics may also be important. Identifying host-specific genetic factors may reveal biological mechanisms of therapeutic relevance and clarify causal relationships of modifiable environmental risk factors for SARS-CoV-2 infection and outcomes. We formed a global network of researchers to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity. Here we describe the results of three genome-wide association meta-analyses that consist of up to 49,562 patients with COVID-19 from 46 studies across 19 countries. We report 13 genome-wide significant loci that are associated with SARS-CoV-2 infection or severe manifestations of COVID-19. Several of these loci correspond to previously documented associations to lung or autoimmune and inflammatory diseases3â7. They also represent potentially actionable mechanisms in response to infection. Mendelian randomization analyses support a causal role for smoking and body-mass index for severe COVID-19 although not for type II diabetes. The identification of novel host genetic factors associated with COVID-19 was made possible by the community of human genetics researchers coming together to prioritize the sharing of data, results, resources and analytical frameworks. This working model of international collaboration underscores what is possible for future genetic discoveries in emerging pandemics, or indeed for any complex human disease
The influences of iron characteristics, operating conditions and solution chemistry on contaminants removal by zero-valent iron: A review
- Author
- Agrawal
- Agrawal
- Ahn
- Ali
- Alowitz
- Arnold
- Bae
- Bae
- Bang
- Bennett
- Bi
- Biterna
- Bransfield
- Burris
- Butler
- Calderon
- Chen
- Chen
- Choe
- Choe
- Choi
- Clark
- Cope
- Cwiertny
- Deng
- Devlin
- Dong
- Dong
- Doong
- Dou
- Dries
- Dries
- Eggleston
- Epolito
- Farrell
- Feng
- Fiedor
- Fu
- Geiger
- Gheju
- Giasuddin
- Gillham
- Gotpagar
- Gu
- Guan
- Guan
- Guo
- Guo
- Hassan
- Henderson
- Henderson
- Hernandez
- Hinds
- Huang
- Huang
- Huang
- Hung
- Hwang
- Im
- Jafarpour
- Jeong
- Jeong
- Jiang
- Jinxiang Li
- Johnson
- Johnson
- Johnson
- Joo
- Kanel
- Katsoyiannis
- Keith
- Keum
- Klas
- Klausen
- Klausen
- Klausen
- Kohn
- Kohn
- Kohn
- Köber
- Lai
- Lai
- Lai
- Lee
- Li
- Li
- Liang
- Liang
- Liang
- Liang
- Lien
- Lien
- Lim
- Lin
- Liou
- Lioubashevski
- Lipczynskakochany
- Liu
- Liu
- Liu
- Liu
- Liu
- Liu
- Liu
- Lo
- Mak
- Matheson
- Moore
- Morales
- Mylon
- Nam
- Neumann
- Noubactep
- Noubactep
- Noubactep
- Noubactep
- Noubactep
- Odziemkowski
- Oh
- Oh
- Oh
- Oh
- OâCarroll
- Peak
- Phillips
- Rangsivek
- Rao
- Rietra
- Ritter
- Ritter
- Roberts
- Ruiz
- Sarathy
- Scherer
- Scherer
- Scherer
- Shimizu
- Shokes
- Song
- Song
- Su
- Su
- Su
- Su
- Su
- Sueptitz
- Sun
- Tamara
- Tang
- Tang
- Tang
- Tinglin Huang
- Tratnyek
- Tsang
- Turcio-Ortega
- Tyrovola
- UjvĂĄri
- Velimirovic
- Velimirovic
- Wang
- Wang
- Waskaas
- Westerhoff
- Wilkin
- Williams
- Wu
- Xiao
- Xiaohong Guan
- Xie
- Xie
- Xie
- Xie
- Xiong
- Xu
- Yabusaki
- Yan
- Ye
- Yin
- Yoon
- Yoon
- Yu
- Yuankui Sun
- Zhang
- Zhou
- Zhu
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
Body mass index and complications following major gastrointestinal surgery: a prospective, international cohort study and meta-analysis.
- Author
- 6rhalmi J
- 6zkan Bb
- \u160im\ue1\u10dkov\ue1 B
- \u160irok\ue1 M
- \u17debr\ue1k R
- Aarts E
- Abbas Z
- Abburu S
- Abd Ghaffar Mk
- Abdelgalil R
- Abdelhadi M
- Abdikadir Hr
- Abdulmajid A
- Abdulrahman N
- Abid A
- Abid H
- Abrisqueta Carrion J
- Abuhussein N
- Abul Mh
- Acar S
- Acherman Yiz
- Acquaah F
- Acres M
- Adams R
- Adams Rd
- Adebayo Aa
- Adeleja I
- Adiyaman C
- Adjei H
- Adlan A
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- Agalar C
- Agarwal V
- Agrawal M
- Ahern N
- Ahmad A
- Ahmad K
- Ahmad S
- Ahmed F
- Ahmed H
- Ahmed M
- Ahmed N
- Ahmed S
- Ahn Js
- Aidoo-Micah Ge
- Aildasani L
- Aithie Jm
- Akbulut F
- Akcaoglu T
- Akdogan A
- Akhtar S
- Akkaya E
- Akkucuk S
- Akpunarli B
- Aksoy K
- Aktas Mk
- Aktekin H
- Al-Mousawi A
- Al-Nasser A
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- Al-Obaedi O
- Al-Robeye A
- Albayrak D
- Alberdi San Roman I
- Alberti Delgado P
- Alcazar Montero Ja
- Alcocer Bp
- Alconchel-Gago F
- Aldrey I
- Ali A
- Ali B
- Ali H
- Ali M
- Ali S
- Alim Ye
- Aliseda-Jover D
- Alizadeh M
- Aljbour A
- Aljbour I
- Allan C
- Allen Jly
- Allot R
- Alonso Gon\ue7alves S
- Alonso Hernandez N
- Altintas O
- Altomare Df
- Alvarez Reyes I
- Amajuoyi A
- Amarelo Garcia M
- Ambrona-Zafra D
- Amelung Fj
- Amin H
- Amin O
- Amphlett Ah
- Anabitarte O
- Anakwenze V
- Anandarajah C
- Anania G
- Anconelli D
- Anderson L
- Anderson Lb
- Anderson Rgj
- Anderson Sm
- Ang A
- Angelov S
- Anilkumar A
- Anim-Addo N
- Ankarali T
- Ansari N
- Antoniou I
- Anyan-Brown J
- Aonzo P
- Apicella M
- Aquilino F
- Aray E
- Archer Ch
- Archer M
- Arcudi C
- Arenal Jj
- Arezzo A
- Argenti F
- Arif T
- Arora E
- Arrigo A
- Arslan E
- Arslan U
- Arthurs B
- Arukan C
- Arun C
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- Ashfaq U
- Ashken L
- Ashraf S
- Ashraf Sf
- Ashton Aj
- Ashwood J
- Asik M
- Aslan L
- Aslanyan A
- Asma A
- Asmadi A
- Assadullah S
- Atalay H
- Atasoy H
- Atayi A
- Atesavci Sn
- Atif M
- Atraszkiewicz Ba
- Attalla M
- Austreng L
- Auyoung E
- Avery P
- Axelson T
- Ayaz B
- Aydar Seyi
- Aytekin A
- Aziz H
- Aziz N
- Babaoglu H
- Bach S
- Badia Jm
- Badii B
- Badran A
- Baeten Cim
- Bagaglini G
- Bagley J
- Bahcecioglu B
- Baixauli J
- Baker An
- Baker C
- Bakewell Zr
- Bakhsh A
- Baki Be
- Balagna P
- Balaji S
- Balci B
- Baldwin A
- Bali An
- Balian V
- Bamac E
- Bamgbose Fa
- Bandirmali O
- Barai I
- Barmayehvar B
- Barnes J
- Barone V
- Barrera Gomez M
- Barrow Tr
- Barthorpe Ae
- Bartlett J
- Bartlett Rd
- Barto\u161 M
- Barton Ec
- Bartrina Soler P
- Baskoy L
- Bassam N
- Bassett J
- Bassiony S
- Bastiaansen Ajnm
- Bath Mf
- Batho A
- Batt E
- Baykan B
- Bayoumy Ab
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- Bazeer Hz
- Beaver D
- Becerra Nieves M
- Beckett J
- Beecroft S
- Behar N
- Bektur G
- Belia F
- Belibagli Zo
- Bell A
- Bell L
- Bell N
- Bellinato M
- Bellio G
- Beltr\ue1n de Heredia J
- Bemand Tp
- Bemelman Wa
- Benevento A
- Benli S
- Berends F
- Bergara T
- Bernstein I
- Bertelli Puche Jl
- Bes\u131s\u131k Hm
- Bethell Gs
- Beyatli S
- Bhanderi S
- Bhangu A
- Bhaskaran G
- Bhatt N
- Bhatti M
- Bhome R
- Bhudia R
- Bianchini S
- Bianco F
- Bilgin S
- Bilicen G
- Bilici O
- Binbuga M
- Bingham G
- Birgin Bz
- Blanco Antona F
- Blanco-Colino R
- Blege Hk
- Blessed R
- Blonk L
- Bloomer J
- Bloomfield T
- Blore Cd
- Bober Dn
- Bodur S
- Boersma Am
- Bokkerink G
- Bolat Ab
- Bolton L
- Bolton W
- Bonouvrie D
- Bonsu S
- Bookless Lr
- Boom Ms
- Borrellas A
- Bos K
- Boschetti Me
- Bose R
- Botchey S
- Botrugno Em
- Bottini C
- Boulton Aj
- Boxall N
- Boyle J
- Bozkurt Gk
- Bradley C
- Braganza L
- Brathwaite-Shirley C
- Bravo M
- Brecher J
- Bremner Rh
- Brennan C
- Brennan D
- Brennan E
- Brennan K
- Brent G
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- Brewer Cf
- Brewster O
- Bright M
- Britton F
- Brogan A
- Brown D
- Brown E
- Brown Ej
- Brown Fs
- Broyd A
- Brueren L
- Bruno M
- Brzyska K
- Buakuma P
- Buchan Am
- Buckle Rt
- Bucko Am
- Bulley F
- Bullman Lm
- Bullock Np
- Burger Bhcm
- Burgess A
- Burke D
- Burke E
- Burke J
- Burney Lj
- Buyukkarabacak Y
- Buyukkasap C
- C\uf3rdoba-D\uedaz de Laspra E
- Caballero Rodriguez E
- Caballero L
- Cakaloglu Hc
- Cakir E
- Cakir Sg
- Calar Sn
- Calcagno P
- Calisgan B
- Caliskan T
- Callan R
- Cammarota A
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- Campion A
- Can Tatar O
- Canbay Torun B
- Candilio G
- Cannav\uf2 M
- Canning E
- Canning N
- Cantelo J
- Cantimer E
- Cao Y
- Capozzolo A
- Cardwell Ae
- Carlson S
- Caro Gonzalez Mp
- Carr L
- Carr R
- Carroll Af
- Carter D
- Carthew L
- Cartwright E
- Casagranda B
- Castiglione F
- Catalano M
- Caudullo G
- Cautiero R
- Cazzola Fe
- Celen D
- Celik B
- Celik E
- Celik K
- Celik S
- Cengiz U
- Cetin Sk
- Cetinkaya M
- Ceylan C
- Chamberlain M
- Chan C
- Chan N
- Chandan N
- Chapman Sj
- Charalambos Ma
- Charalambous G
- Charania A
- Charavanamuttu V
- Chaudhary M
- Chaudhry Fi
- Chaudhry Ww
- Checa Guillen M
- Checcacci P
- Cheema H
- Cheema J
- Chen Jh
- Chen M
- Chen X
- Cheng K
- Chervenkoff J
- Cheskes L
- Chetta N
- Cheung F
- Chew L
- Chew Ls
- Chhabra A
- Chhina C
- Chilima Cp
- Chillarge G
- Chilvers Nj
- Chin H
- Chin R
- Chisholm Eg
- Chitnis Ar
- Chiu Sm
- Choi J
- Choi Pj
- Chong Bf
- Chong J
- Choo Kp
- Chrastek D
- Chua Ey
- Chung A
- Cianchi F
- Ciano P
- Ciccioli E
- Ciciliot M
- Ciftci E
- Cin S
- Cinar S
- Cise S
- Cisternino G
- Ciurleo C
- Claireaux Ha
- Claramonte Bellmunt O
- Clark Ij
- Clarke Ak
- Cleere J
- Clement Kd
- Clerico G
- Clesham K
- Clifford T
- Coates A
- Coco C
- Cody A
- Cody N
- Coffey Cj
- Coffey D
- Coffin J
- Cok H
- Cole Sj
- Collier H
- Collins A
- Collins D
- Collins P
- Collinson S
- Colombo Em
- Colombo F
- Consten Ecj
- Cooper D
- Cooper Ge
- Copley Hc
- Copley Pc
- Cornish E
- Corte M
- Coskun O
- Costa A
- Costa-Navarro D
- Cotton A
- Coughlan G
- Coulson R
- Cox Se
- Coyne P
- Craig Ar
- Craig E
- Craig-McQuaide A
- Craven K
- Cremers D
- Crewdson Ja
- Croall A
- Crozier L
- Cruciani C
- Cruz Reyes Ja
- Cuckow L
- Cullen C
- Cullen S
- Culleton G
- Cumber E
- Cumber Em
- Cumen Ec
- Cumming S
- Cundy Oj
- Cunha P
- Curletti G
- Curran A
- Cuthbert G
- Cymes W
- D\uedaz Padillo A
- Dalci K
- Danal\u131oglu An
- Daoub A
- Darr S
- Das M
- Datta U
- Davies J
- Davies Je
- Davies K
- Davies N
- Davies Sc
- Davis-Hall M
- Dawar R
- Dawson Pm
- de Andres Olabarria U
- de Bernier Gl
- de Boer Dv
- De Boni D
- de Bruin M
- de Castro Smm
- de Gooyer Jm
- de Groof Ej
- de Groof J
- de Guerre Levm
- de Hingh I
- de Jesus Rodriguez Perdomo M
- de la Portilla de Juan F
- de la Rosa-Estadella M
- De la Torre Conde C
- De Luca E
- De Manzini N
- de Mees T
- De Nardi P
- de Roy van Zuidewijn D
- De Serra Tejada I
- de Vos Tot Nederveen Cappel Rj
- de Wilt H
- de Zeeuw S
- Deall C
- Dean R
- Dean S
- Dean W
- Dear K
- Deas G
- Debenham R
- Decorato A
- Deekonda P
- Del Coco F
- Del Mar L\uf3pez-Cuevas M
- Delf J
- Delgado At
- Deliktas Ts
- Delport A
- Demetri Am
- Demir F
- Demirci A
- Demirci K
- Demirci Zs
- Demirtas B
- Dennis R
- Dennis Yf
- Derbyshire L
- Detmers Blom Fpn
- Devabalan Y
- Devlin E
- Dewdney Cj
- Dhanji A
- Dhar M
- Dhutia Aj
- Di Benedetto L
- Di Girolami L
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- Dominguez-Prieto V
- Dorman C
- Dosa T
- Doshi A
- Doyle J
- Drake Tm
- Drislane C
- Dronkers Wj
- Du\u161ek T
- Dube P
- Duffy A
- Duinhouwer Le
- Duke K
- Duncumb Jw
- Dunn Ce
- Dur\ue1n-Mart\uednez M
- Duran Mu\uf1oz-Cruzado Vm
- Durmaz H
- Durr A
- Durrani B
- Dutt S
- Dyal Ar
- Dynes K
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- Edison Ma
- Edozie F
- Edwards Ja
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- Eggen Y
- Ekin B
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- Elliott Le
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- English W
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- Entwisle Jh
- Eparh K
- Eragat M
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- Erdem S
- Erdogan P
- Erel T
- Ergul B
- Erol Hi
- Eroz E
- Erozgur B
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- Escalona Canal Mg
- Esp\ued Mac\uedas A
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- Esposto R
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- Facchiano A
- Falcon Cazas A
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- Forrest Pr
- Forte B
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- Francescon Ct
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- Frank Al
- Frasson M
- Fulgencio Barbarin J
- Fung Tmp
- G\uf3mez-L\uf3pez de San Rom\ue1n C
- G\ufcven H
- Gabriel J
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- Gallo G
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- Garcia Cruz G
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- Harding F
- Hardy Mr
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- Mirdavoudi V
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- Williams Mr
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- Ziff O
- Zigiotto D
- Zijlmans Jl
- Zimmerman D
- Ziprin P
- Zope S
- Zuhair M
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2018
- Field of study
AIM:
Previous studies reported conflicting evidence on the effects of obesity on outcomes after gastrointestinal surgery. The aims of this study were to explore the relationship of obesity with major postoperative complications in an international cohort and to present a meta-analysis of all available prospective data.
METHODS:
This prospective, multicentre study included adults undergoing both elective and emergency gastrointestinal resection, reversal of stoma or formation of stoma. The primary end-point was 30-day major complications (Clavien-Dindo Grades III-V). A systematic search was undertaken for studies assessing the relationship between obesity and major complications after gastrointestinal surgery. Individual patient meta-analysis was used to analyse pooled results.
RESULTS:
This study included 2519 patients across 127 centres, of whom 560 (22.2%) were obese. Unadjusted major complication rates were lower in obese vs normal weight patients (13.0% vs 16.2%, respectively), but this did not reach statistical significance (P = 0.863) on multivariate analysis for patients having surgery for either malignant or benign conditions. Individual patient meta-analysis demonstrated that obese patients undergoing surgery for malignancy were at increased risk of major complications (OR 2.10, 95% CI 1.49-2.96, P < 0.001), whereas obese patients undergoing surgery for benign indications were at decreased risk (OR 0.59, 95% CI 0.46-0.75, P < 0.001) compared to normal weight patients.
CONCLUSIONS:
In our international data, obesity was not found to be associated with major complications following gastrointestinal surgery. Meta-analysis of available prospective data made a novel finding of obesity being associated with different outcomes depending on whether patients were undergoing surgery for benign or malignant disease
Body mass index and complications following major gastrointestinal surgery: A prospective, international cohort study and meta-analysis
- Author
- Aarts E
- Abbas Z
- Abburu S
- Abd Ghaffar Mk
- Abdelgalil R
- Abdelhadi M
- Abdikadir Hr
- Abdulmajid A
- Abdulrahman N
- Abid A
- Abid H
- Abrisqueta Carrion J
- Abuhussein N
- Abul Mh
- Acar S
- Acherman Yiz
- Acquaah F
- Acres M
- Adams R
- Adams Rd
- Adebayo Aa
- Adeleja I
- Adiyaman C
- Adjei H
- Adlan A
- Afzal Z
- Agalar C
- Agarwal V
- Agrawal M
- Ahern N
- Ahmad A
- Ahmad K
- Ahmad S
- Ahmed F
- Ahmed H
- Ahmed M
- Ahmed N
- Ahmed S
- Ahn Js
- Aidoo-Micah Ge
- Aildasani L
- Aithie Jm
- Akbulut F
- Akcaoglu T
- Akdogan A
- Akhtar S
- Akkaya E
- Akkucuk S
- Akpunarli B
- Aksoy K
- Aktas Mk
- Aktekin H
- Al-Mousawi A
- Al-Nasser A
- Al-Nasser Z
- Al-Obaedi O
- Al-Robeye A
- Albayrak D
- Alberdi San Roman I
- Alberti Delgado P
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- Xiao C
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- Yetiskin E
- Yıgman S
- Yildirim N
- Yildirim R
- Yildiz S
- Yildiz Ss
- Yildiz T
- Yilmaz I
- Yilmaz M
- Yilmaz S
- Yilmaz T
- Yim N
- Yoganathan S
- Yong Cs
- Yong N
- Yoruk I
- Yousif A
- Yow L
- Yuen R
- Yuksek B
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- Yuksel A
- Yurdaor Ss
- Yurekli Am
- Zaidi R
- Zegeye Mi
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- Ziff O
- Zigiotto D
- Zijlmans Jl
- Zimmerman D
- Ziprin P
- Zope S
- Zuhair M
- Ărhalmi J
- Ăzkan Bb
- Ć imĂĄÄkovĂĄ B
- Ć irokĂĄ M
- ĆœebrĂĄk R
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2018
- Field of study
Aim Previous studies reported conflicting evidence on the effects of obesity on outcomes after gastrointestinal surgery. The aims of this study were to explore the relationship of obesity with major postoperative complications in an international cohort and to present a metaanalysis of all available prospective data. Methods This prospective, multicentre study included adults undergoing both elective and emergency gastrointestinal resection, reversal of stoma or formation of stoma. The primary end-point was 30-day major complications (Clavien\u2013Dindo Grades III\u2013V). A systematic search was undertaken for studies assessing the relationship between obesity and major complications after gastrointestinal surgery. Individual patient meta-analysis was used to analyse pooled results. Results This study included 2519 patients across 127 centres, of whom 560 (22.2%) were obese. Unadjusted major complication rates were lower in obese vs normal weight patients (13.0% vs 16.2%, respectively), but this did not reach statistical significance (P = 0.863) on multivariate analysis for patients having surgery for either malignant or benign conditions. Individual patient meta-analysis demonstrated that obese patients undergoing surgery formalignancy were at increased risk of major complications (OR 2.10, 95% CI 1.49\u20132.96, P < 0.001), whereas obese patients undergoing surgery for benign indications were at decreased risk (OR 0.59, 95% CI 0.46\u20130.75, P < 0.001) compared to normal weight patients. Conclusions In our international data, obesity was not found to be associated with major complications following gastrointestinal surgery. Meta-analysis of available prospective data made a novel finding of obesity being associated with different outcomes depending on whether patients were undergoing surgery for benign or malignant disease
Mapping the human genetic architecture of COVID-19
- Author
- Abdelrazik M
- Abdullah T
- Abe R
- Abe S
- Abecasis GR
- Abel L
- Abernathy C
- Abraheem A
- Abul-Husn NS
- Acosta-Herrera M
- Acquilini D
- Acquilini D
- Adachi T
- Adachi Y
- Adams C
- Adams K
- Adanini O
- Adeleye O
- Adeniji K
- Adra D
- Afifi N
- Afilalo J
- Afilalo M
- Afolabi D
- Afrasiabi Z
- Afset JE
- Agasou A
- Aghemo A
- Agranoff D
- Agrawal S
- Aguirre LA
- Agwuh K
- Ahmad HF
- Ahmad N
- Ahmed A
- Ahmed C
- Ahmed KA
- Ai M
- Ail D
- Akeroyd L
- Akhtar MN
- Akhtar S
- Akinkugbe O
- Aksentijevich A
- Al Thani A
- Al-Muftah W
- Al-Sarraj Y
- Alarcon C
- Alarcon-Riquelme ME
- Alasdair F
- Alaverdian D
- Alavere H
- Albertos R
- Albillos A
- Albrecht W
- Albrich W
- Albrich WC
- Aldera EL
- Aldridge J
- Alegria A
- Alex B
- Alexander P
- Alfonso J
- Algera AG
- Ali A
- Ali IMA
- Ali S
- Aliberti S
- Allan A
- Allan E
- Allan J
- Alldis Z
- Allen L
- Allen S
- Allibone S
- Allison KS
- Allos R
- Ally SM
- Almaden-Boyle C
- Altabaibeh A
- Altmueller J
- Alvaro A
- Amar D
- Amin V
- Amitrano S
- Amiya S
- Ampuero J
- Anan R
- Anania S
- Anastasescu E
- Anderson F
- Anderson J
- Anderson M
- Anderson P
- Anderson S
- Anderson S
- Anderson T
- Ando A
- Andolfo I
- Andrade V
- Andretta F
- Andreucci E
- Andreucci E
- Andrew A
- Andrew B
- Andrew G
- Andrews E
- Andrews SJ
- Andrews SJ
- Andrews SJ
- Andrews SJ
- Andrikopoulos P
- Anedda F
- Aneli S
- Anemoli V
- Angelini C
- Angus B
- Annis A
- Antcliffe D
- Antinori A
- Antoni MD
- Anumakonda V
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- Cosgrove D
- Cosier T
- Cossarizza A
- Costantino G
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- Coton Z
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- de Gordoa LO-R
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- De Grandi A
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- de Jong MD
- De la Horra C
- De Neef M
- de Pablo R
- de Rojas I
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- De Vivo O
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- di Bartolomeo C
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- Yoshiyama T
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- Zanelli G
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- Zechner M
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- Zoller H
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- Zongo O
- zu Bentrup FM
- Zucchi P
- Zwinderman AHK
- Zyndorf M
- Publication venue
- Publication date
- 01/01/2021
- Field of study
The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors have a role in the chance of exposure to SARS-CoV-2 and the severity of COVID-191,2, host genetics may also be important. Identifying host-specific genetic factors may reveal biological mechanisms of therapeutic relevance and clarify causal relationships of modifiable environmental risk factors for SARS-CoV-2 infection and outcomes. We formed a global network of researchers to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity. Here we describe the results of three genome-wide association meta-analyses that consist of up to 49,562 patients with COVID-19 from 46 studies across 19 countries. We report 13 genome-wide significant loci that are associated with SARS-CoV-2 infection or severe manifestations of COVID-19. Several of these loci correspond to previously documented associations to lung or autoimmune and inflammatory diseases3,4,5,6,7. They also represent potentially actionable mechanisms in response to infection. Mendelian randomization analyses support a causal role for smoking and body-mass index for severe COVID-19 although not for type II diabetes. The identification of novel host genetic factors associated with COVID-19 was made possible by the community of human genetics researchers coming together to prioritize the sharing of data, results, resources and analytical frameworks. This working model of international collaboration underscores what is possible for future genetic discoveries in emerging pandemics, or indeed for any complex human disease
Multi-messenger Observations of a Binary Neutron Star Merger
- Author
- Aab A.
- Aar G.Van
- Aartsen M.G.
- Abbott B.P.
- Abbott R.
- Abbott T.D.
- Abbott T.M.C.
- Abdalla H.
- Abe F.
- Abeysekara A.U.
- Abramo L.R.
- Abramowski A.
- Abreu P.
- Acernese F.
- Acero F.
- Ackermann M.
- Ackley K.
- Ackley K.
- Adams C.
- Adams J.
- Adams S.M.
- Adams T.
- Addesso P.
- Adhikari R.X.
- Adya V.B.
- Affeldt C.
- Afrough M.
- Agarwal B.
- Agathos M.
- Agatsuma K.
- Aggarwal N.
- Aglietta M.
- Agliozzo C.
- Agudo I.
- Aguiar O.D.
- Aguilar J.A.
- Aharonian F.
- Ahlers M.
- Ahrens M.
- Aiello L.
- Ain A.
- Ajith P.
- Akras S.
- Albert A.
- Albert A.
- Albuquerque I.F.M.
- Albury J.M.
- Alcaniz J.S.
- Alexander K.D.
- Alfaro R.
- Allam S.
- Allekotte I.
- Allen B.
- Allen G.
- Allison J.R.
- Allocca A.
- Almeida R.M.De
- Almela A.
- Altin P.A.
- Altmann D.
- Alvarez C.
- Alvarez-Muñiz J.
- Amati L.
- Amato A.
- An T.
- Ananyeva A.
- Anastasi G.A.
- Anchordoqui L.
- Andeen K.
- Anderson J.P.
- Anderson S.B.
- Anderson T.
- Anderson W.G.
- Andrada B.
- Andreoni I.
- Andreoni I.
- Andringa S.
- André M.
- Angelova S.V.
- Anghinolfi M.
- Angus C.R.
- AngĂŒner E.O.
- Annis J.
- Ansseau I.
- Antier S.
- Anton G.
- Antonelli L.A.
- Antonelli L.A.
- Anupama G.C.
- Aoki K.
- Aoki W.
- Appert S.
- Aptekar R.L.
- Arai K.
- Arakawa M.
- Aramo C.
- Araya M.C.
- Arcavi I.
- Arceo R.
- Ardid M.
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- Ălvarez J.D.
- Ălvarez M.Dovale
- Ć mĂda R.
- Ć upĂk J.
- ƻarnecki A.F.
- ƻywucka N.
- Publication venue
- 'American Astronomical Society'
- Publication date
- 01/01/2017
- Field of study
International audienceOn 2017 August 17 a binary neutron star coalescence candidate (later designated GW170817) with merger time 12:41:04 UTC was observed through gravitational waves by the Advanced LIGO and Advanced Virgo detectors. The Fermi Gamma-ray Burst Monitor independently detected a gamma-ray burst (GRB 170817A) with a time delay of âŒ1.7s with respect to the merger time. From the gravitational-wave signal, the source was initially localized to a sky region of 31 deg(2) at a luminosity distance of 40â8+8â Mpc and with component masses consistent with neutron stars. The component masses were later measured to be in the range 0.86 to 2.26 Mââ. An extensive observing campaign was launched across the electromagnetic spectrum leading to the discovery of a bright optical transient (SSS17a, now with the IAU identification of AT 2017gfo) in NGC 4993 (at âŒ40Mpc) less than 11 hours after the merger by the One-Meter, Two Hemisphere (1M2H) team using the 1 m Swope Telescope. The optical transient was independently detected by multiple teams within an hour. Subsequent observations targeted the object and its environment. Early ultraviolet observations revealed a blue transient that faded within 48 hours. Optical and infrared observations showed a redward evolution over âŒ10 days. Following early non-detections, X-ray and radio emission were discovered at the transientâs position âŒ9 and âŒ16 days, respectively, after the merger. Both the X-ray and radio emission likely arise from a physical process that is distinct from the one that generates the UV/optical/near-infrared emission. No ultra-high-energy gamma-rays and no neutrino candidates consistent with the source were found in follow-up searches. These observations support the hypothesis that GW170817 was produced by the merger of two neutron stars in NGC 4993 followed by a short gamma-ray burst (GRB 170817A) and a kilonova/macronova powered by the radioactive decay of r-process nuclei synthesized in the ejecta