110 research outputs found
Los obstáculos epistemológicos del turismo como dominio de saber.16H334
Se realizó un análisis de las perspectivas teóricas que predominan en los
encuadres investigativos del turismo y que provienen de otros dominios del saber. En
consecuencia, se trató de indagar en esos encuadres desde las mismas disciplinas que los
concibieron, procurando identificar en ellos tanto puntos de encuentro como de rupturas
epistémicos. Este análisis condujo a visibilizar aquello que al interior del campo discursivo
del turismo no aparece como evidente y que, consecuentemente, al transponerlos mediante
su aplicación a dicho campo, producen desviaciones, distorsiones y/o resignificaciones
respecto de su significación original, las que operan como obstáculos epistemológicos. Estos
últimos impiden la emergencia de nuevas formaciones discursivas a través de las cuales
puedan producirse nuevos sentidos y significados a los objetos estudiados e investigados.
Para tal propósito, su principal anclaje estuvo centrado en el análisis de las fuentes
bibliográficas más referenciadas por los productores de conocimiento de este dominio. Se
trata de un estudio explicativo, abordado desde el enfoque pragmático de la perspectiva
teórico-metodológica foucaultiana. Dicho enfoque se circunscribe a la repercusión del “efecto
de verdad” sobre las prácticas que, en este caso, son las realizadas por los sujetos
productores de conocimiento
De las articulaciones entre el subcampo profesional y el subcampo de investigaci ón al interior del Campo académico de las Carreras de Licenciatura en. 16H380
Se trata de un proyecto que continúa la línea de investigación que este equipo viene desarrollando desde hace alrededor de nueve años, y que
ha intentado dar cuenta de las características y particularidades del estado del conocimiento en el campo de investigación del turismo. En esta
instancia, en especial, desde el marco teórico-metodológico que ofrece la Teoría de los Campos, se procurará conocer las articulaciones
existentes entre producción, transmisión y transferencia de conocimientos. Para ello se analizarán, de modo relacional, las publicaciones que
den cuenta de proyectos de investigación (período 2001-2012) sobre las temáticas de Desarrollo Local y Sustentabilidad, los planes de estudio
y los Programas de las asignaturas vinculadas con estas temáticas
Famílies botàniques de plantes medicinals
Facultat de Farmàcia, Universitat de Barcelona. Ensenyament: Grau de Farmàcia, Assignatura: Botànica Farmacèutica, Curs: 2013-2014, Coordinadors: Joan Simon, Cèsar Blanché i
Maria Bosch.Els materials que aquí es presenten són els recull de 175 treballs d’una família botànica d’interès medicinal realitzats de manera individual. Els treballs han estat realitzat
per la totalitat dels estudiants dels grups M-2 i M-3 de l’assignatura Botànica Farmacèutica
durant els mesos d’abril i maig del curs 2013-14. Tots els treballs s’han dut a terme a través de la plataforma de GoogleDocs i han estat tutoritzats pel professor de l’assignatura i revisats i finalment co-avaluats entre els propis estudiants. L’objectiu principal de l’activitat ha estat fomentar l’aprenentatge autònom i col·laboratiu en Botànica farmacèutica
Why Pleiotropic Interventions are Needed for Alzheimer's Disease
Alzheimer's disease (AD) involves a complex pathological cascade thought to be initially triggered by the accumulation of β-amyloid (Aβ) peptide aggregates or aberrant amyloid precursor protein (APP) processing. Much is known of the factors initiating the disease process decades prior to the onset of cognitive deficits, but an unclear understanding of events immediately preceding and precipitating cognitive decline is a major factor limiting the rapid development of adequate prevention and treatment strategies. Multiple pathways are known to contribute to cognitive deficits by disruption of neuronal signal transduction pathways involved in memory. These pathways are altered by aberrant signaling, inflammation, oxidative damage, tau pathology, neuron loss, and synapse loss. We need to develop stage-specific interventions that not only block causal events in pathogenesis (aberrant tau phosphorylation, Aβ production and accumulation, and oxidative damage), but also address damage from these pathways that will not be reversed by targeting prodromal pathways. This approach would not only focus on blocking early events in pathogenesis, but also adequately correct for loss of synapses, substrates for neuroprotective pathways (e.g., docosahexaenoic acid), defects in energy metabolism, and adverse consequences of inappropriate compensatory responses (aberrant sprouting). Monotherapy targeting early single steps in this complicated cascade may explain disappointments in trials with agents inhibiting production, clearance, or aggregation of the initiating Aβ peptide or its aggregates. Both plaque and tangle pathogenesis have already reached AD levels in the more vulnerable brain regions during the “prodromal” period prior to conversion to “mild cognitive impairment (MCI).” Furthermore, many of the pathological events are no longer proceeding in series, but are going on in parallel. By the MCI stage, we stand a greater chance of success by considering pleiotropic drugs or cocktails that can independently limit the parallel steps of the AD cascade at all stages, but that do not completely inhibit the constitutive normal functions of these pathways. Based on this hypothesis, efforts in our laboratories have focused on the pleiotropic activities of omega-3 fatty acids and the anti-inflammatory, antioxidant, and anti-amyloid activity of curcumin in multiple models that cover many steps of the AD pathogenic cascade (Cole and Frautschy, Alzheimers Dement 2:284–286, 2006)
Measurement of b hadron lifetimes in exclusive decays containing a J/psi in p-pbar collisions at sqrt(s)=1.96TeV
We report on a measurement of -hadron lifetimes in the fully reconstructed
decay modes B^+ -->J/Psi K+, B^0 --> J/Psi K*, B^0 --> J/Psi Ks, and Lambda_b
--> J/Psi Lambda using data corresponding to an integrated luminosity of 4.3
, collected by the CDF II detector at the Fermilab Tevatron. The
measured lifetimes are B^+ = , B^0 = and Lambda_b = . The lifetime ratios are B^+/B^0 = and Lambda_b/B^0 = . These are the most precise determinations
of these quantities from a single experiment.Comment: revised version. accepted for PRL publicatio
Measurement of ZZ production in leptonic final states at {\surd}s of 1.96 TeV at CDF
In this paper we present a precise measurement of the total ZZ production
cross section in pp collisions at {\surd}s= 1.96 TeV, using data collected with
the CDF II detector corresponding to an integrated luminosity of approximately
6 fb-1. The result is obtained by combining separate measurements in the
four-charged (lll'l'), and two-charged-lepton and two-neutral-lepton (llvv)
decay modes of the Z. The combined measured cross section for pp {\to} ZZ is
1.64^(+0.44)_(-0.38) pb. This is the most precise measurement of the ZZ
production cross section in 1.96 TeV pp collisions to date.Comment: submitted to Phys. Rev. Let
Supplement: "Localization and broadband follow-up of the gravitational-wave transient GW150914" (2016, ApJL, 826, L13)
This Supplement provides supporting material for Abbott et al. (2016a). We briefly summarize past electromagnetic (EM) follow-up efforts as well as the organization and policy of the current EM follow-up program. We compare the four probability sky maps produced for the gravitational-wave transient GW150914, and provide additional details of the EM follow-up observations that were performed in the different bands
Multi-messenger observations of a binary neutron star merger
On 2017 August 17 a binary neutron star coalescence candidate (later designated GW170817) with merger time 12:41:04 UTC was observed through gravitational waves by the Advanced LIGO and Advanced Virgo detectors. The Fermi Gamma-ray Burst Monitor independently detected a gamma-ray burst (GRB 170817A) with a time delay of ~1.7 s with respect to the merger time. From the gravitational-wave signal, the source was initially localized to a sky region of 31 deg2 at a luminosity distance of 40+8-8 Mpc and with component masses consistent with neutron stars. The component masses were later measured to be in the range 0.86 to 2.26 Mo. An extensive observing campaign was launched across the electromagnetic spectrum leading to the discovery of a bright optical transient (SSS17a, now with the IAU identification of AT 2017gfo) in NGC 4993 (at ~40 Mpc) less than 11 hours after the merger by the One- Meter, Two Hemisphere (1M2H) team using the 1 m Swope Telescope. The optical transient was independently detected by multiple teams within an hour. Subsequent observations targeted the object and its environment. Early ultraviolet observations revealed a blue transient that faded within 48 hours. Optical and infrared observations showed a redward evolution over ~10 days. Following early non-detections, X-ray and radio emission were discovered at the transient’s position ~9 and ~16 days, respectively, after the merger. Both the X-ray and radio emission likely arise from a physical process that is distinct from the one that generates the UV/optical/near-infrared emission. No ultra-high-energy gamma-rays and no neutrino candidates consistent with the source were found in follow-up searches. These observations support the hypothesis that GW170817 was produced by the merger of two neutron stars in NGC4993 followed by a short gamma-ray burst (GRB 170817A) and a kilonova/macronova powered by the radioactive decay of r-process nuclei synthesized in the ejecta
Localization and broadband follow-up of the gravitational-wave transient GW150914
A gravitational-wave (GW) transient was identified in data recorded by the Advanced Laser Interferometer Gravitational-wave Observatory (LIGO) detectors on 2015 September 14. The event, initially designated G184098 and later given the name GW150914, is described in detail elsewhere. By prior arrangement, preliminary estimates of the time, significance, and sky location of the event were shared with 63 teams of observers covering radio, optical, near-infrared, X-ray, and gamma-ray wavelengths with ground- and space-based facilities. In this Letter we describe the low-latency analysis of the GW data and present the sky localization of the first observed compact binary merger. We summarize the follow-up observations reported by 25 teams via private Gamma-ray Coordinates Network circulars, giving an overview of the participating facilities, the GW sky localization coverage, the timeline, and depth of the observations. As this event turned out to be a binary black hole merger, there is little expectation of a detectable electromagnetic (EM) signature. Nevertheless, this first broadband campaign to search for a counterpart of an Advanced LIGO source represents a milestone and highlights the broad capabilities of the transient astronomy community and the observing strategies that have been developed to pursue neutron star binary merger events. Detailed investigations of the EM data and results of the EM follow-up campaign are being disseminated in papers by the individual teams
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