172 research outputs found
Search for the standard model Higgs boson at LEP
- Author
- Abbaneo D
- Abbaneo D
- Abbiendi G
- Abbiendi G
- Abdallah J
- Abreu P
- Achard P
- Adam W
- Adriani O
- Adzic P
- Affholderbach K
- Aguilar-Benitez M
- Ainsley C
- Akesson PF
- Albrecht T
- Alcaraz J
- Alderweireld T
- Alemanni G
- Alemany-Fernandez R
- Alexander G
- Allaby J
- Allison J
- Allmendinger T
- Allport PP
- Aloisio A
- Alviggi MG
- Amaldi U
- Amapane N
- Amaral P
- Amato S
- Anagnostou G
- Anashkin E
- Anderhub H
- Anderson KJ
- Andreazza A
- Andreev VP
- Andringa S
- Anjos N
- Anselmo F
- Antilogus P
- Antonelli A
- Antonelli M
- Apel WD
- Arcelli S
- Arefiev A
- Armstrong SR
- Arnoud Y
- Asai S
- Ask S
- Asman B
- Augustin JE
- Augustinus A
- Awunor O
- Axen D
- Azemoon T
- Aziz T
- Azuelos G
- Azzurri P
- Baarmand M
- Badaud F
- Bagliesi G
- Bagnaia P
- Bailey I
- Baillon P
- Bajo A
- Baksay G
- Baksay L
- Baldew SV
- Ballestrero A
- Bambade P
- Banerjee S
- Banerjee S
- Barate R
- Barate R
- Barberio E
- Barbier R
- Barczyk A
- Bardin D
- Barillere R
- Barker G
- Barklow T
- Barlow RJ
- Baroncelli A
- Bartalini P
- Basile M
- Batalova N
- Batley RJ
- Battaglia M
- Battiston R
- Baubillier M
- Bay A
- Becattini F
- Bechtle P
- Becker U
- Becks KH
- Begalli M
- Behner F
- Behnke T
- Behrmann A
- Bell KW
- Bell PJ
- Bella G
- Bellerive A
- Bellucci L
- Ben-Haim E
- Bencivenni G
- Benekos N
- Benelli G
- Benvenuti A
- Berat C
- Berbeco R
- Berdugo J
- Berges P
- Berggren M
- Berkelman K
- Berntzon L
- Bertrand D
- Bertucci B
- Besancon M
- Besson N
- Betev BL
- Bethke S
- Beuselinck R
- Biasini M
- Biebell O
- Biglietti M
- Biland A
- Binnie DM
- Blair GA
- Blaising JJ
- Bloch D
- Bloch-Devaux B
- Blom M
- Blondel A
- Bloodworth IJ
- Bluj M
- Blumenschein U
- Blyth SC
- Bobbink GJ
- Boccali T
- Bock P
- Boeriun O
- Bohm A
- Bohrer A
- Boix G
- Boldizsar L
- Bologna G
- Bonacorsi D
- Bonesini M
- Bonissent A
- Boonekamp M
- Booth CN
- Booth PSL
- Borean C
- Borgia B
- Borisov G
- Bossi F
- Botner O
- Boucrot J
- Bouhova-Thacker E
- Boumediene D
- Bouquet B
- Bourilkov D
- Bourquin M
- Boutemeur M
- Bowcock TJV
- Bowdery CK
- Boyko I
- Braccini S
- Bracko M
- Braibant S
- Brandt S
- Branson JG
- Bravo S
- Brenner R
- Brient JC
- Brigliadori L
- Brochu F
- Brodet E
- Brown RM
- Bruckman P
- Bruneliere R
- Brunet JM
- Buchmuller O
- Buesser K
- Bugge L
- Buijs A
- Burckhart HJ
- Burger JD
- Burger WJ
- Buschmann P
- Cai XD
- Callot O
- Calvi M
- Cameron W
- Campana R
- Campana S
- Camporesi T
- Canale V
- Capell M
- Capon G
- Carena F
- Carlino G
- Carnegie RK
- Caron B
- Carr J
- Cartacci A
- Carter AA
- Carter JR
- Cartwright S
- Casado MP
- Casaus J
- Castro N
- Cattaneo A
- Cavallari F
- Cavallo F
- Cavallo N
- Cavanaugh R
- Cecchi C
- Cerrada M
- Cerutti F
- Chamizo M
- Chang CY
- Chang YH
- Chapkin M
- Charlton DG
- Charpentier P
- Checchia P
- Chemarin M
- Chen A
- Chen G
- Chen GM
- Chen HF
- Chen HS
- Chiarella V
- Chiefari G
- Chierici R
- Chiliapnikov P
- Chmeissani M
- Chudoba J
- Chung SU
- Cieslik K
- Cifarelli L
- Cindolo F
- Ciulli V
- Clare I
- Clare R
- Clarke DP
- Clerbaux B
- Clifft RW
- Coignet G
- Colaleo A
- Colas P
- Coles J
- Colino N
- Collins P
- Combley F
- Contri R
- Cosme G
- Cossutti F
- Costa MJ
- Costantini S
- Cowan G
- Coyle P
- Cranmer K
- Crawley B
- Creanza D
- Crennell D
- Crespo JM
- Csilling A
- Cucciarelli S
- Cuevas J
- Cuffiani M
- Curtil C
- D'Hondt J
- da Silva T
- Da Silva W
- Dado S
- Dai TS
- Dallavalle GM
- Dallison S
- Dalmau J
- David A
- Davier M
- Davies G
- De Angelis A
- de Asmundis R
- De Boer W
- De Bonis I
- De Clercq C
- De Filippis N
- de Guevara PL
- de Jong R
- de la Cruz B
- De Lotto B
- De Maria N
- De Min A
- de Palma M
- de Paula L
- De Roeck A
- De Salvo A
- De Vivie de Regie JB
- De Wolf EA
- Debreczeni J
- Decamp D
- Deglon P
- Degre A
- Deiters K
- Della Ricca G
- della Volpe D
- Delmeire E
- Denes P
- DeNotaristefani F
- Desch K
- Dessagne S
- Dhamotharan S
- Di Ciaccio L
- Di Simone A
- Diemoz M
- Dienes B
- Dierckxsens M
- Dietl H
- Dionisi C
- Dissertori G
- Dittmar M
- Donkers M
- Doria A
- Dornan PJ
- Doroba K
- Dova MT
- Drees J
- Drevermann H
- Dris M
- Dubbert J
- Duchesneau D
- Duchovni E
- Duckeck G
- Duerdoth IP
- Duflot L
- Duinker P
- Ealet A
- Echenard B
- Edgecock TR
- Eigen G
- Ekelof T
- El Mamouni H
- Elfgren E
- Eline A
- Ellert M
- Ellis G
- Elsing M
- Engler A
- Eppling FJ
- Etzion E
- Ewers A
- Extermann P
- Fabbri F
- Fabbro B
- Falagan MA
- Falciano S
- Falvard A
- Fanourakis G
- Fassouliotis D
- Favara A
- Fay J
- Fayolle D
- Fedin O
- Feindt M
- Felcini M
- Feld L
- Ferguson DPS
- Ferguson T
- Fernandez E
- Fernandez J
- Fernandez-Bosman M
- Ferrari P
- Ferrer A
- Ferro F
- Fesefeldt H
- Fiandrini E
- Fiedler F
- Field JH
- Filthaut F
- Finch AJ
- Fisher PH
- Fisher W
- Fisk I
- Flagmeyer U
- Fleck I
- Foa L
- Focardi E
- Foeth H
- Fokitis E
- Forconi G
- Ford M
- Forty RW
- Foster F
- Fouchez D
- Frank M
- Freudenreich K
- Frey A
- Fulda-Quenzer F
- Furetta C
- Furtjes A
- Fuster J
- Gagnon P
- Galaktionov Y
- Gandelman M
- Ganguli SN
- Ganis G
- Gao Y
- Garcia C
- Garcia-Abia P
- Garcia-Bellido A
- Garrido L
- Gary JW
- Gataullin M
- Gavillet P
- Gay P
- Gaycken G
- Gazis E
- Geich-Gimbel C
- Gentile S
- Geweniger C
- Ghete VM
- Giacomelli G
- Giacomelli P
- Giagu S
- Giammanco A
- Giannini G
- Gianotti F
- Giassi A
- Girone M
- Girtler P
- Giunta M
- Gokieli R
- Goldberg J
- Golob B
- Gomez-Ceballos G
- Goncalves P
- Gong ZF
- Gonzalez S
- Goy C
- Grauges E
- Graziani E
- Green MG
- Greening TC
- Grenier G
- Grimm O
- Grivaz JF
- Grosdidier G
- Gross E
- Gruenewald MW
- Grunhaus J
- Grupen C
- Gruwe M
- Grzelak K
- Guida M
- Gunther PO
- Gupta A
- Gupta VK
- Gurtu A
- Gutay LJ
- Guy J
- Haag C
- Haas D
- Hajdu C
- Hallgren A
- Hamacher K
- Hamann M
- Hamilton K
- Hanke P
- Hansen J
- Hansen JB
- Hansen JD
- Hansen JR
- Hansen PH
- Hanson GG
- Harder K
- Harel A
- Harin-Dirac M
- Harvey J
- Hatzifotiadou D
- Haug S
- Hauler F
- Hauschild M
- Hauschildt J
- Hawkes CM
- Hawkings R
- Hayes OJ
- He H
- Hebbeker T
- Hedberg V
- Heister A
- Hemingway RJ
- Henneche M
- Hensel C
- Hepp V
- Herr H
- Herten G
- Herve A
- Hess J
- Heuer RD
- Heusse P
- Hill JC
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- Hodgson PN
- Hofer H
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- Holmgren SO
- Holt PJ
- Holzner G
- Homer RJ
- Horvath D
- Hou SR
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- Huang X
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- Huntemeyer P
- Hutchcroft DE
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- Ishii K
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- Jarry P
- Jeans D
- Jeremie H
- Jezequel S
- Jin BN
- Jin S
- Johansson EK
- Johansson PD
- Jones LT
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- Jones RWL
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- Joram C
- Josa-Mutuberria I
- Jost B
- Jousset J
- Jovanovic P
- Jungermann L
- Junk TR
- Kachelhoffer T
- Kado M
- Kafer D
- Kanaya N
- Kanzaki J
- Kapusta F
- Karapetian G
- Karlen D
- Kartvelishvili V
- Katsanevas S
- Katsoufis E
- Kaur M
- Kawagoe K
- Kawamoto T
- Kayser F
- Keeler RK
- Kellogg RG
- Kennedy BW
- Kennedy J
- Kernel G
- Kersevan BP
- Kienzle-Focacci MN
- Kiiskinen A
- Kile J
- Kim DH
- Kim JK
- King BT
- Kirkby J
- Kittel W
- Kjaer NJ
- Klein K
- Kleinknecht K
- Klier A
- Klimentov A
- Kluge EE
- Kluit P
- Kluth S
- Kneringer E
- Kobayashi T
- Kobel M
- Kokkinias P
- Komamiya S
- Konig AC
- Konstantinidis N
- Kopal M
- Kormos L
- Kourkoumelis C
- Koutsenko V
- Kouznetsov O
- Kowalewski RV
- Kraber M
- Kraemer RW
- Kramer T
- Krenz W
- Kress T
- Krieger P
- Krop D
- Kruger A
- Kruger K
- Krumstein Z
- Kucharczyk M
- Kuhn D
- Kunin A
- Kupper M
- Kyriakis A
- Lafferty GD
- Laktineh I
- Lamsa J
- Lancon E
- Landi G
- Landsman H
- Lanske D
- Laurelli P
- Layter JG
- Le Coultre P
- Le Goff JM
- Lebeau M
- Lebedev A
- Lebrun P
- Lecomte P
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- Lees JP
- Lehto M
- Leibenguth G
- Leinonen L
- Leins A
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- Leitner R
- Lellouch D
- Lemaire MC
- Lemaitre V
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- Leroy O
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- Letts J
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- Liko D
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- Litke AM
- Liu ZA
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- Lohmann W
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- Macpherson A
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- Malgeri L
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- Marchant TE
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- Mazzucato F
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- Mc Nulty R
- McDonald WJ
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- Moreno S
- Morettini P
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- Moutoussi A
- Muanza GS
- Mueller U
- Muenich K
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- Muryn B
- Musicar B
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- Napolitano M
- Nassiakou M
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- Newman H
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- Nicolaidou R
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- Nilsson BS
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- Vossebeld J
- Vrba V
- Waananen A
- Wachsmuth H
- Wadhwa M
- Wahlen H
- Waller D
- Wallraff W
- Wang M
- Wang T
- Wang XL
- Wang ZM
- Ward CP
- Ward DR
- Ward JJ
- Washbrook AJ
- Wasserbacch S
- Watkins PM
- Watson AT
- Watson NK
- Weber M
- Weiser C
- Well PS
- Wengler T
- Wermes N
- Werner S
- Wetterling D
- White R
- Wicke D
- Wickens J
- Wiedenmann W
- Wienemann P
- Wilkens H
- Wilkinson G
- Wilson GW
- Wilson JA
- Winter M
- Witek M
- Wolf G
- Wolf G
- Wu J
- Wu SL
- Wu SX
- Wu X
- Wunsch M
- Wyatt TR
- Wynhoff S
- Xia L
- Xie Y
- Xu R
- Xu ZZ
- Xue S
- Yamamoto J
- Yamashita S
- Yang BZ
- Yang CG
- Yang HJ
- Yang M
- Yeh SC
- Yuan C
- Yushchenko O
- Zachariadou K
- Zalewska A
- Zalewski P
- Zalite A
- Zalite Y
- Zavrtanik D
- Zeitnitz C
- Zer-Zion D
- Zhang J
- Zhang L
- Zhang ZP
- Zhao J
- Zhao W
- Zhu GY
- Zhu RY
- Zhuang HL
- Zhuravlov V
- Zichichi A
- Ziegler T
- Zilizi G
- Zimin NI
- Zimmermann B
- Zintchenko A
- Zito G
- Zivkovic L
- Zobernig G
- Zoller M
- Zupan M
- Publication venue
- ELSEVIER SCIENCE BV
- Publication date
- 17/07/2003
- Field of study
Search for new phenomena in final states with an energetic jet and large missing transverse momentum in pp collisions at √ s = 8 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abbott DC
- Abeling K
- Abhayasinghe DK
- Abidi SH
- AbouZeid OS
- Abraham NL
- Abramowicz H
- Abreu H
- Abud AA
- Abulaiti Y
- Acharya BS
- Achkar B
- Adachi S
- Adam L
- Adamczyk L
- Adamek L
- Adelman J
- Adersberger M
- Adiguzel A
- Adorni S
- Adye T
- Affolder AA
- Afik Y
- Agapopoulou C
- Agaras MN
- Aggarwal A
- Agheorghiesei C
- Aguilar-Saavedra JA
- Ahmadov F
- Ahmed WS
- Ai X
- Aielli G
- Akatsuka S
- Akesson TPA
- Akilli E
- Akimov A
- Al Khoury K
- Alberghi GL
- Albert J
- Alderweireldt S
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexopoulos T
- Alfonsi A
- Alfonsi F
- Alhroob M
- Ali B
- Aliev M
- Alimonti G
- Allaire C
- Allbrooke BMM
- Allen BW
- Allport PP
- Aloisio A
- Alonso F
- Alpigiani C
- Alshehri AA
- Alvarez Estevez M
- Alviggi MG
- Amaral Coutinho Y
- Ambler A
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- Andreazza A
- Andrei V
- Anelli CR
- Angelidakis S
- Angerami A
- Anisenkov A
- Annovi A
- Antel C
- Anthony MT
- Antipov E
- Antonelli M
- Antrim DJA
- Anulli F
- Aoki M
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- Araujo Ferraz V
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- Araya ST
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- Arce ATH
- Arduh FA
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- Argyropoulos S
- Arling J-H
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- Castelijn R
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- Castillo Gimenez V
- Castillo FL
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- Catinaccio A
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- Cattai A
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- Cavasinni V
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- Cerda Alberich L
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- Cerri A
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- Chapman JD
- Chargeishvili B
- Charlton DG
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- Cheng HJ
- Cheplakov A
- Cheremushkina E
- Cheu E
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- Chevalerias TJA
- Chevalier L
- Chiarella V
- Chiarelli G
- Chiodini G
- Chisholm AS
- Chitan A
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- Chiu YH
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- Chouridou S
- Chow YS
- Chu MC
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- Chudoba J
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- Chytka L
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- Ciesla KM
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- Ciubotaru DA
- Ciungu BM
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- Corga KDV
- Cormier F
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- Dam M
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- Dann NS
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- David C
- Davidek T
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- Dawson I
- De Asmundis R
- De Beurs M
- De Castro S
- De Cecco S
- De Groot N
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- De Pedis D
- De Regie JBDV
- de Renstrom PAB
- De Sa RCL
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- Dedovich D
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- Denisov SP
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2015
- Field of study
Results of a search for new phenomena in final states with an energetic jet and large missing transverse momentum are reported. The search uses 20.3 fb−1 of √ s = 8 TeV data collected in 2012 with the ATLAS detector at the LHC. Events are required to have at least one jet with pT > 120 GeV and no leptons. Nine signal regions are considered with increasing missing transverse momentum requirements between Emiss T > 150 GeV and Emiss T > 700 GeV. Good agreement is observed between the number of events in data and Standard Model expectations. The results are translated into exclusion limits on models with either large extra spatial dimensions, pair production of weakly interacting dark matter candidates, or production of very light gravitinos in a gauge-mediated supersymmetric model. In addition, limits on the production of an invisibly decaying Higgs-like boson leading to similar topologies in the final state are presente
Measurement of the inclusive and dijet cross-sections of b-jets in pp collisions at sqrt(s) = 7 TeV with the ATLAS detector
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- 'Springer Science and Business Media LLC'
- Publication date
- 31/12/2010
- Field of study
The inclusive and dijet production cross-sections have been measured for jets
containing b-hadrons (b-jets) in proton-proton collisions at a centre-of-mass
energy of sqrt(s) = 7 TeV, using the ATLAS detector at the LHC. The
measurements use data corresponding to an integrated luminosity of 34 pb^-1.
The b-jets are identified using either a lifetime-based method, where secondary
decay vertices of b-hadrons in jets are reconstructed using information from
the tracking detectors, or a muon-based method where the presence of a muon is
used to identify semileptonic decays of b-hadrons inside jets. The inclusive
b-jet cross-section is measured as a function of transverse momentum in the
range 20 < pT < 400 GeV and rapidity in the range |y| < 2.1. The bbbar-dijet
cross-section is measured as a function of the dijet invariant mass in the
range 110 < m_jj < 760 GeV, the azimuthal angle difference between the two jets
and the angular variable chi in two dijet mass regions. The results are
compared with next-to-leading-order QCD predictions. Good agreement is observed
between the measured cross-sections and the predictions obtained using POWHEG +
Pythia. MC@NLO + Herwig shows good agreement with the measured bbbar-dijet
cross-section. However, it does not reproduce the measured inclusive
cross-section well, particularly for central b-jets with large transverse
momenta.Comment: 10 pages plus author list (21 pages total), 8 figures, 1 table, final
version published in European Physical Journal
Jet energy measurement with the ATLAS detector in proton-proton collisions at root s=7 TeV
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdesselam A
- Abdinov O
- Abi B
- Abolins M
- Abramowicz H
- Abreu H
- Acerbi E
- Acharya BS
- Adams DL
- Addy TN
- Adelman J
- Aderholz M
- Adomeit S
- Adragna P
- Adye T
- Aefsky S
- Aguilar-Saavedra JA
- Aharrouche M
- Ahlen SP
- Ahles F
- Ahmad A
- Ahsan M
- Aielli G
- Akdogana T
- Akesson TPA
- Akimoto G
- Akimov AV
- Akiyama A
- Aktas A
- Alam MA
- Alam MS
- Albert J
- Albrand S
- Aleksa M
- Aleksandrov IN
- Alessandria F
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Aliev M
- Alimonti G
- Alison J
- Aliyev M
- Allport PP
- Allwood-Spiers SE
- Almenar CC
- Almond J
- Aloisio A
- Alon R
- Alonso A
- Alviggi MG
- Amako K
- Amaral P
- Amelung C
- Ammosov VV
- Amorim A
- Amoros G
- Amram N
- Anastopoulos C
- Ancu LS
- Andari N
- Andeen T
- Anders CF
- Anders G
- Anderson KJ
- Andreazza A
- Andrei V
- Andrieux M-L
- Anduaga XS
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- Anghinolfi F
- Anh TV
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- Antonaki A
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- Antonov A
- Antos J
- Anulli F
- Aoun S
- Apolle R
- Arabidze G
- Aracena I
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- Archambault JP
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- Zutshi V
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/03/2013
- Field of study
The jet energy scale and its systematic uncertainty are determined for jets measured with the ATLAS detector at the LHC in proton-proton collision data at a centre-of-mass energy of √s = 7TeV corresponding to an integrated luminosity of 38 pb-1. Jets are reconstructed with the anti-kt algorithm with distance parameters R=0. 4 or R=0. 6. Jet energy and angle corrections are determined from Monte Carlo simulations to calibrate jets with transverse momenta pT≥20 GeV and pseudorapidities {pipe}η{pipe}<4. 5. The jet energy systematic uncertainty is estimated using the single isolated hadron response measured in situ and in test-beams, exploiting the transverse momentum balance between central and forward jets in events with dijet topologies and studying systematic variations in Monte Carlo simulations. The jet energy uncertainty is less than 2. 5 % in the central calorimeter region ({pipe}η{pipe}<0. 8) for jets with 60≤pT<800 GeV, and is maximally 14 % for pT<30 GeV in the most forward region 3. 2≤{pipe}η{pipe}<4. 5. The jet energy is validated for jet transverse momenta up to 1 TeV to the level of a few percent using several in situ techniques by comparing a well-known reference such as the recoiling photon pT, the sum of the transverse momenta of tracks associated to the jet, or a system of low-pT jets recoiling against a high-pT jet. More sophisticated jet calibration schemes are presented based on calorimeter cell energy density weighting or hadronic properties of jets, aiming for an improved jet energy resolution and a reduced flavour dependence of the jet response. The systematic uncertainty of the jet energy determined from a combination of in situ techniques is consistent with the one derived from single hadron response measurements over a wide kinematic range. The nominal corrections and uncertainties are derived for isolated jets in an inclusive sample of high-pT jets. Special cases such as event topologies with close-by jets, or selections of samples with an enhanced content of jets originating from light quarks, heavy quarks or gluons are also discussed and the corresponding uncertainties are determined. © 2013 CERN for the benefit of the ATLAS collaboration
Alternative splicing of exon 10 in the tau gene as a target for treatment of tauopathies
- Author
- A Andreadis
- A Boutajangout
- A Delacourte
- A Grover
- A Kramer
- A Rojo
- AC Goldstrohm
- AD Sperfeld
- AM Pittman
- B Kalbfuss
- BL Goode
- BR Graveley
- C Andreassi
- C Conrad
- C Rizzini
- CL Lendon
- CL Lin
- CL Lorson
- DC Glatz
- DD Coovert
- DL Black
- DW Cleveland
- F Hernandez
- G Bai
- GS Wang
- H Amrein
- I D'Souza
- I D'Souza
- I D'Souza
- J Villemaire
- JA Berglund
- JF Caceres
- Jianhua Zhou
- JK Taylor
- JM Gallo
- JR Murrell
- JR Murrell
- JW Connell
- K Inoue
- K Nakai
- KC Wilhelmsen
- L Cartegni
- LA Skordis
- LI Binder
- M Aoki
- M Baker
- M Goedert
- M Goedert
- M Goedert
- M Hasegawa
- M Hutton
- M Ingelsson
- M Puttaraju
- M Tian
- M van Slegtenhorst
- M Wijker
- M Yasuda
- M Zhang
- MD Weingarten
- MG Spillantini
- MG Spillantini
- MJ Moore
- MR Lunn
- N Sergeant
- NL Foster
- O Bugiani
- P LoPresti
- P Pastor
- P Poorkaj
- P Poorkaj
- PC Wong
- PJ Grabowski
- PM Stanford
- Q Yu
- Qingming Yu
- QS Gao
- RA Crowther
- S Kondo
- S Lefebvre
- S Pickering-Brown
- S Schraen-Maschke
- T Crowther
- T Rodriguez-Martin
- TA Cooper
- TD Bird
- TH Coady
- Tie Zou
- VM Lee
- W Chun
- XD Fu
- Y Hua
- Y Wang
- Z Jiang
- Z Jiang
- Publication venue
- BioMed Central
- Publication date
- 01/01/2008
- Field of study
Tau aggregation is one of the major features in Alzheimer's disease and in several other tauopathies, including frontotemporal dementia with Parkinsonism linked to chromosome 17 (FTDP-17), and progressive supranuclear palsy (PSP). More than 35 mutations in the tau gene have been identified from FTDP-17 patients. A group of these mutations alters splicing of exon 10, resulting in an increase in exon 10 inclusion into tau mRNA. Abnormal splicing with inclusion of exon 10 into tau mRNA has also been observed in PSP and AD patients. These results indicate that abnormal splicing of exon 10, leading to the production of tau with exon 10, is probably one of the mechanisms by which tau accumulates and aggregates in tauopathic brains. Therefore, modulation of exon 10 splicing in the tau gene could potentially be targeted to prevent tauopathies. To identify small molecules or compounds that could potentially be developed into drugs to treat tauopathies, we established a cell-based high-throughput screening assay. In this review, we will discuss how realistic, specific biological molecules can be found to regulate exon 10 splicing in the tau gene for potential treatment of tauopathies
The impact of viral mutations on recognition by SARS-CoV-2 specific T cells.
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- Abudahab K
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- Adeniji K
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- Agranoff D
- Agwuh K
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- Aldera EL
- Alegria A
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- Allara E
- Allen S
- Amato R
- Andrikopoulos P
- Angus B
- Angyal A
- Annett T
- Aplin S
- Ariani CV
- Armstrong JA
- Asad H
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- Ashish A
- Ashworth M
- Asiimwe IG
- Atkinson D
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- Attwood SW
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- Bicknell K
- Binns D
- Birchley A
- Bird PW
- Bishop C
- Blacow R
- Blakey V
- Blane B
- Bogaert D
- Bolt F
- Bonfield J
- Bonner S
- Bonsall D
- Booth L
- Boswell T
- Bosworth A
- Bothma P
- Bourgeois Y
- Boyd O
- Bradley DT
- Breen C
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- Breuer J
- Bridgett S
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- Publication venue
- iScience
- Publication date
- 01/01/2021
- Field of study
We identify amino acid variants within dominant SARS-CoV-2 T cell epitopes by interrogating global sequence data. Several variants within nucleocapsid and ORF3a epitopes have arisen independently in multiple lineages and result in loss of recognition by epitope-specific T cells assessed by IFN-γ and cytotoxic killing assays. Complete loss of T cell responsiveness was seen due to Q213K in the A∗01:01-restricted CD8+ ORF3a epitope FTSDYYQLY207-215; due to P13L, P13S, and P13T in the B∗27:05-restricted CD8+ nucleocapsid epitope QRNAPRITF9-17; and due to T362I and P365S in the A∗03:01/A∗11:01-restricted CD8+ nucleocapsid epitope KTFPPTEPK361-369. CD8+ T cell lines unable to recognize variant epitopes have diverse T cell receptor repertoires. These data demonstrate the potential for T cell evasion and highlight the need for ongoing surveillance for variants capable of escaping T cell as well as humoral immunity.This work is supported by the UK Medical Research Council (MRC); Chinese Academy of Medical Sciences(CAMS) Innovation Fund for Medical Sciences (CIFMS), China; National Institute for Health Research (NIHR)Oxford Biomedical Research Centre, and UK Researchand Innovation (UKRI)/NIHR through the UK Coro-navirus Immunology Consortium (UK-CIC). Sequencing of SARS-CoV-2 samples and collation of data wasundertaken by the COG-UK CONSORTIUM. COG-UK is supported by funding from the Medical ResearchCouncil (MRC) part of UK Research & Innovation (UKRI),the National Institute of Health Research (NIHR),and Genome Research Limited, operating as the Wellcome Sanger Institute. T.I.d.S. is supported by a Well-come Trust Intermediate Clinical Fellowship (110058/Z/15/Z). L.T. is supported by the Wellcome Trust(grant number 205228/Z/16/Z) and by theUniversity of Liverpool Centre for Excellence in Infectious DiseaseResearch (CEIDR). S.D. is funded by an NIHR GlobalResearch Professorship (NIHR300791). L.T. and S.C.M.are also supported by the U.S. Food and Drug Administration Medical Countermeasures Initiative contract75F40120C00085 and the National Institute for Health Research Health Protection Research Unit (HPRU) inEmerging and Zoonotic Infections (NIHR200907) at University of Liverpool inpartnership with Public HealthEngland (PHE), in collaboration with Liverpool School of Tropical Medicine and the University of Oxford.L.T. is based at the University of Liverpool. M.D.P. is funded by the NIHR Sheffield Biomedical ResearchCentre (BRC – IS-BRC-1215-20017). ISARIC4C is supported by the MRC (grant no MC_PC_19059). J.C.K.is a Wellcome Investigator (WT204969/Z/16/Z) and supported by NIHR Oxford Biomedical Research Centreand CIFMS. The views expressed are those of the authors and not necessarily those of the NIHR or MRC
Multi-messenger observations of a binary neutron star merger
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- Li XB
- Li XF
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- Parra A
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- Passuello D
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- Pearlstone BL
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- Pekeur NW
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- Piranomonte S
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- Piro AL
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- Pisanu T
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- Poolakkil S
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- Popolizio P
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- Prado RR
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- Principe G
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- Prodi GA
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- Prokoph H
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- Prrer M
- Przybylski GT
- Pulone L
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- Reposeur T
- Resconi E
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- Riviere C
- Rizi V
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- Robie R
- Robinet F
- Rocchi A
- Rochester LS
- Rodi J
- Rodriguez H
- Rojas D Avila
- Rojas-Bravo C
- Rojo J Rodriguez
- Rol E
- Rolland L
- Rollins JG
- Roma VJ
- Romano R
- Romel CL
- Romer AK
- Romero M Dominguez
- Romie JH
- Romoli C
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- Roques J-P
- Rosa-Gonzlez D
- Rosell A Carnero
- Rosenberg M
- Rosetti S
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- Ross MP
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- Rosswog S
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- Roth M
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- Rowlinson A
- Rowlinson A
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- Ruiz R Gracia
- Ruiz-Velasco E
- Rulten CB
- Rumyantsev VV
- Rusu F
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- Ryckbosch D
- Rykoff ES
- Rysewyk D
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- Sadecki T
- Sadeghian L
- Sadler EM
- Sadler EM
- Saffe C
- Saffi SJ
- Saftoiu A
- Sahakian V
- Sai N
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- Saito Y
- Sakamaki A
- Sakamoto T
- Sakellariadou M
- Sako M
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- Salafia OS
- Salamida F
- Salazar H
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- Saleem M
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- Salemi F
- Salina G
- Salmon L
- Salvadori I
- Salvaterra R
- Samajdar A
- Sammut L
- Sampedro L
- Sampson LM
- Samtleben DFE
- Sanchez B
- Sanchez DA
- Sanchez E
- Sanchez EJ
- Sanchez F
- Sanchez LE
- Sanchez-Losa A
- Sanchez-Lucas P
- Sanchez-Ramirez R
- Sanchis-Gual N
- Sand DJ
- Sandberg V
- Sanders JR
- Sandoval A
- Sandrock A
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- Sansom EK
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- Santangelo A
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- Santos EM
- Sapienza P
- Sarazin F
- Sarkar S
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- Sasaki M
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- Satalecka K
- Sathyaprakash BS
- Sato R
- Saulson PR
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- Sauter O
- Savage RL
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- Sawadsky A
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- Schlegel DJ
- Schlickeiser R
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- Schmidt BP
- Schmidt D
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- Schnabel R
- Schneider A
- Schneider M
- Schneiter M
- Schoenell W
- Schoenen S
- Schofield RMS
- Scholten O
- Schonbeck A
- Schoneberg S
- Schoorlemmer H
- Schovnek P
- Schreiber E
- Schroder FG
- Schroder S
- Schroder SL
- Schssler F
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- Schuette D
- Schulte BW
- Schultz ASB
- Schulz A
- Schulz A
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- Schumacher J
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- Schwalbe SG
- Schwanke U
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- Schweyer T
- Sciutto SJ
- Scolnic D
- Scott J
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- Secco LF
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- Segreto A
- Seidel E
- Seitenzahl IR
- Sekiguchi Y
- Sellers D
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- Sengupta AS
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- Sergeev A
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- Seunarine S
- Sevilla-Noarbe I
- Seyffert AS
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- Shah AA
- Shahriar MS
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- Shang Z
- Shannon RM
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- Sharp RG
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- Shilon I
- Shimizu Y
- Shimomukai R
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- Shoemaker DH
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- Siemens X
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- Singer LP
- Singh A
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- Sintes AM
- Siskind EJ
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- Zucker ME
- Zuniga J
- Zweizig J
- Zywucka N
- Publication venue
- 'American Astronomical Society'
- Publication date
- 01/01/2017
- Field of study
On 2017 August 17 a binary neutron star coalescence candidate (later designated GW170817) with merger time 12:41:04 UTC was observed through gravitational waves by the Advanced LIGO and Advanced Virgo detectors. The Fermi Gamma-ray Burst Monitor independently detected a gamma-ray burst (GRB 170817A) with a time delay of ~1.7 s with respect to the merger time. From the gravitational-wave signal, the source was initially localized to a sky region of 31 deg2 at a luminosity distance of 40+8-8 Mpc and with component masses consistent with neutron stars. The component masses were later measured to be in the range 0.86 to 2.26 Mo. An extensive observing campaign was launched across the electromagnetic spectrum leading to the discovery of a bright optical transient (SSS17a, now with the IAU identification of AT 2017gfo) in NGC 4993 (at ~40 Mpc) less than 11 hours after the merger by the One- Meter, Two Hemisphere (1M2H) team using the 1 m Swope Telescope. The optical transient was independently detected by multiple teams within an hour. Subsequent observations targeted the object and its environment. Early ultraviolet observations revealed a blue transient that faded within 48 hours. Optical and infrared observations showed a redward evolution over ~10 days. Following early non-detections, X-ray and radio emission were discovered at the transient’s position ~9 and ~16 days, respectively, after the merger. Both the X-ray and radio emission likely arise from a physical process that is distinct from the one that generates the UV/optical/near-infrared emission. No ultra-high-energy gamma-rays and no neutrino candidates consistent with the source were found in follow-up searches. These observations support the hypothesis that GW170817 was produced by the merger of two neutron stars in NGC4993 followed by a short gamma-ray burst (GRB 170817A) and a kilonova/macronova powered by the radioactive decay of r-process nuclei synthesized in the ejecta
Measurement of the cross-section for b-jets produced in association with a Z boson at root s=7 TeV with the ATLAS detector ATLAS Collaboration
- Author
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- Abdesselam A
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- Yilmaz M
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- Zajacova Z
- Zalite YK
- Zanello L
- Zarzhitsky P
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- Zenin O
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- Zerwas D
- Zhan Z
- Zhang D
- Zhang H
- Zhang J
- Zhang X
- Zhang Z
- Zhao L
- Zhao T
- Zhao Z
- Zhemchugov A
- Zheng S
- Zhong J
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- Zhu CG
- Zhu H
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- Zhu Y
- Zhuang X
- Zhuravlov V
- Zieminska D
- Zimmermann R
- Zimmermann S
- Zimmermann S
- Ziolkowski M
- Zitoun R
- Zivkovic L
- Zmouchko VV
- Zobernig G
- Zoccoli A
- Zolnierowski Y
- Zsenei A
- zur Nedden M
- Zutshi V
- Zwalinski L
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2011
- Field of study
A measurement is presented of the inclusive cross-section for b-jet production in association with a Z boson in pp collisions at a centre-of-mass energy of root s = 7 TeV. The analysis uses the data sample collected by the ATLAS experiment in 2010, corresponding to an integrated luminosity of approximately 36 pb(-1). The event selection requires a Z boson decaying into high P-T electrons or muons, and at least one b-jet, identified by its displaced vertex, with transverse momentum p(T) > 25 GeV and rapidity vertical bar y vertical bar < 2.1. After subtraction of background processes, the yield is extracted from the vertex mass distribution of the candidate b-jets. The ratio of this cross-section to the inclusive Z cross-section (the average number of b-jets per Z event) is also measured. Both results are found to be in good agreement with perturbative QCD predictions at next-to-leading order
Search for long-lived, massive particles in events with a displaced vertex and a muon with large impact parameter in pp collisions at root s=13 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abbott DC
- Abeling K
- Abhayasinghe DK
- Abidi SH
- AbouZeid OS
- Abraham NL
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- Yildiz HD
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- Zahreddine J
- Zaitsev AM
- Zakareishvili T
- Zakharchuk N
- Zambito S
- Zanzi D
- Zaripovas DR
- Zeissner S
- Zeitnitz C
- Zemaityte G
- Zeng JC
- Zenin O
- Zenis T
- Zerwas D
- Zgubic M
- Zhang B
- Zhang DF
- Zhang G
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- Zhang L
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- Zhang X
- Zhang Y
- Zhang Z
- Zhang Z
- Zhao P
- Zhao Y
- Zhao Z
- Zhemchugov A
- Zheng Z
- Zhong D
- Zhou B
- Zhou C
- Zhou M
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- Zhou N
- Zhou Y
- Zhu C
- Zhu CG
- Zhu H
- Zhu HL
- Zhu J
- Zhu Y
- Zhuang X
- Zhukov K
- Zhulanov V
- Zieminska D
- Zimine N
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zivkovic L
- Zobernig G
- Zoccoli A
- Zoch K
- Zorbas TG
- Zou R
- Zu Theenhausen HM
- Zwalinski L
- Publication venue
- AMER PHYSICAL SOC
- Publication date
- 01/08/2020
- Field of study
A search for long-lived particles decaying into hadrons and at least one muon is presented. The analysis selects events that pass a muon or missing-transverse-momentum trigger and contain a displaced muon track and a displaced vertex. The analyzed dataset of proton-proton collisions at
√
s
=
13 TeV
was collected with the ATLAS detector and corresponds to
136
fb
−
1. The search employs dedicated reconstruction techniques that significantly increase the sensitivity to long-lived particle decays that occur in the ATLAS inner detector. Background estimates for Standard Model processes and instrumental effects are extracted from data. The observed event yields are compatible with those expected from background processes. The results are presented as limits at 95% confidence level on model-independent cross sections for processes beyond the Standard Model, and interpreted as exclusion limits in scenarios with pair production of long-lived top squarks that decay via a small
R
-parity-violating coupling into a quark and a muon. Top squarks with masses up to 1.7 TeV are excluded for a lifetime of 0.1 ns, and masses below 1.3 TeV are excluded for lifetimes between 0.01 ns and 30 ns
Erratum: Measurement of angular and momentum distributions of charged particles within and around jets in Pb + Pb and pp collisions at √sNN = 5.02 TeV with the ATLAS detector [Phys. Rev. C 100 , 064901 (2019)]
- Author
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- Abbott B
- Abbott Dc
- Abed Abud A
- Abeling K
- Abhayasinghe Dk
- Abidi Sh
- Abouzeid Os
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- Abramowicz H
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- Abulaiti Y
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- Achkar B
- Adachi S
- Adam Bourdarios C
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- Adamczyk L
- Adamek L
- Adelman J
- Adersberger M
- Adiguzel A
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- Alberghi Gl
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- Alderweireldt S
- Aleksa M
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- Alexa C
- Alexandre D
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- Alfonsi A
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- Alvarez Piqueras D
- Alviggi Mg
- Amaral Coutinho Y
- Ambler A
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- Angelidakis S
- Angerami A
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- Bednyakov Va
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- Biebel O
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- Bielski R
- Bierwagen K
- Biesuz Nv
- Biglietti M
- Billoud Trv
- Bindi M
- Bingul A
- Bini C
- Biondi S
- Birman M
- Bisanz T
- Biswal Jp
- Biswas D
- Bitadze A
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- Bjorke K
- Black Km
- Blazek T
- Bloch I
- Blocker C
- Blue A
- Blumenschein U
- Bobbink Gj
- Bobrovnikov Vs
- Bocchetta Ss
- Bocci A
- Boerner D
- Bogavac D
- Bogdanchikov Ag
- Bohm C
- Boisvert V
- Bokan P
- Bold T
- Boldyrev As
- Bolz Ae
- Bomben M
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- Borecka-Bielska Hm
- Borisov A
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- Boscherini D
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- Bossio Sola Jd
- Bouaouda K
- Boudreau J
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- Boveia A
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- Breaden Madden Wd
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- Briglin Dl
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- Brock I
- Brock R
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- Brooks Wk
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- Broughton Jh
- Bruckman De Renstrom Pa
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- Bruni A
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- Bruni Ls
- Bruno S
- Brunt Bh
- Bruschi M
- Bruscino N
- Bryant P
- Bryngemark L
- Buanes T
- Buat Q
- Buchholz P
- Buckley Ag
- Budagov Ia
- Bugge Mk
- Buhrer F
- Bulekov O
- Burch Tj
- Burdin S
- Burgard Cd
- Burger Am
- Burghgrave B
- Burr Jtp
- Burton Cd
- Burzynski Jc
- Buscher V
- Buschmann E
- Bussey Pj
- Butler Jm
- Buttar Cm
- Butterworth Jm
- Butti P
- Buttinger W
- Buxo Vazquez Cj
- Buzatu A
- Buzykaev Ar
- Cabras G
- Cabrera Urban S
- Caforio D
- Cai H
- Cairo Vmm
- Cakir O
- Calace N
- Calafiura P
- Calandri A
- Calderini G
- Calfayan P
- Callea G
- Caloba Lp
- Calvente Lopez S
- Calvet D
- Calvet S
- Calvet Tp
- Calvetti M
- Camacho Toro R
- Camarda S
- Camarero Munoz D
- Camarri P
- Cameron D
- Caminal Armadans R
- Camincher C
- Campana S
- Campanelli M
- Camplani A
- Campoverde A
- Canale V
- Canesse A
- Cano Bret M
- Cantero J
- Cao T
- Cao Y
- Capeans Garrido Mdm
- Capua M
- Cardarelli R
- Cardillo F
- Carducci G
- Carli I
- Carli T
- Carlino G
- Carlson Bt
- Carminati L
- Carney Rmd
- Caron S
- Carquin E
- Carra S
- Carter Jws
- Casado Mp
- Casha Af
- Casper Dw
- Castelijn R
- Castillo Gimenez V
- Castillo Fl
- Castro Nf
- Catinaccio A
- Catmore Jr
- Cattai A
- Caudron J
- Cavaliere V
- Cavallaro E
- Cavalli-Sforza M
- Cavasinni V
- Celebi E
- Ceradini F
- Cerda Alberich L
- Cerny K
- Cerqueira As
- Cerri A
- Cerrito L
- Cerutti F
- Cervelli A
- Cetin Sa
- Chadi Z
- Chakraborty D
- Chan Sk
- Chan Ws
- Chan Wy
- Chapman Jd
- Chargeishvili B
- Charlton Dg
- Charman Tp
- Chau Cc
- Che S
- Chekanov S
- Chekulaev Sv
- Chelkov Ga
- Chelstowska Ma
- Chen B
- Chen C
- Chen Ch
- Chen H
- Chen J
- Chen J
- Chen S
- Chen Sj
- Chen X
- Chen Y
- Chen Y-
- Cheng Hc
- Cheng Hj
- Cheplakov A
- Cheremushkina E
- Cherkaoui El Moursli R
- Cheu E
- Cheung K
- Chevalerias Tja
- Chevalier L
- Chiarella V
- Chiarelli G
- Chiodini G
- Chisholm As
- Chitan A
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- Yu J
- Yuan R
- Yue X
- Yuen Spy
- Zaazoua M
- Zabinski B
- Zacharis G
- Zaffaroni E
- Zahreddine J
- Zaitsev Am
- Zakareishvili T
- Zakharchuk N
- Zambito S
- Zanzi D
- Zaripovas Dr
- Zeissner Sv
- Zeitnitz C
- Zemaityte G
- Zeng Jc
- Zenin O
- Zenis T
- Zerwas D
- Zgubic M
- Zhang B
- Zhang Df
- Zhang G
- Zhang H
- Zhang J
- Zhang L
- Zhang L
- Zhang M
- Zhang R
- Zhang X
- Zhang Y
- Zhang Z
- Zhang Z
- Zhao P
- Zhao Y
- Zhao Z
- Zhemchugov A
- Zheng Z
- Zhong D
- Zhou B
- Zhou C
- Zhou M
- Zhou Ms
- Zhou N
- Zhou Y
- Zhu C
- Zhu Cg
- Zhu H
- Zhu Hl
- Zhu J
- Zhu Y
- Zhuang X
- Zhukov K
- Zhulanov V
- Zieminska D
- Zimine Ni
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zivkovic L
- Zobernig G
- Zoccoli A
- Zoch K
- Zorbas Tg
- Zou R
- Zwalinski L
- Publication venue
- American Physical Society
- Publication date
- 01/01/2020
- Field of study
- …