49 research outputs found
Characterization and in vitro cytocompatibility of an acid-etched titanium surface
- Author
- Publication venue
- Fundação Odontológica de Ribeirão Preto
- Publication date
- 01/01/2010
- Field of study
The aims of this study were to characterize the microstructure of a commercially pure titanium (cpTi) surface etched with HCl/H2SO4 (AE-cpTi) and to investigate its in vitro cytocompatibility compared to turned cpTi (T-cpTi). T-cpTi showed a grooved surface and AE-cpTi revealed a surface characterized by the presence of micropits. Surface parameters indicated that the AE-cpTi surface is more isotropic and present a greater area compared to T-cpTi. The oxide film thickness was similar between both surfaces; however, AE-cpTi presented more Ti and O and less C. Osteoblastic cell proliferation, alkaline phosphatase activity, and bone-like nodule formation were greater on T-cpTi than on AE-cpTi. These results show that acid etching treatment produced a surface with different topographical and chemical features compared to the turned one, and such surface modification affected negatively the in vitro cytocompatibility of cpTi as demonstrated by decreasing culture growth and expression of osteoblastic phenotype.O objetivo deste estudo foi caracterizar a microestrutura de uma superfície de titânio comercialmente puro (cpTi) condicionada com HCl/H2SO4 (acid etched) (AE-cpTi) e investigar sua citocompatibilidade in vitro, comparada à do cpTi usinado (turned) (T-cpTi). O T-cpTi apresentou uma superfície com sulcos e o AE-cpTi exibiu uma superfície caracterizada pela presença de micro-vales. Os parâmetros de superfície indicaram que a superfície AE-cpTi é mais isotrópica e apresenta uma área maior quando comparada à superfície T-cpTi. A espessura da camada de óxido foi similar para as duas superfícies; no entanto, a AE-cpTi apresentou maiores quantidades de Ti e O e menor, de C. A proliferação de células osteoblásticas, a atividade de fosfatase alcalina e a formação de matriz mineralizada foram maiores na superfície T-cpTi que na AE-cpTi. Esses resultados mostram que o condicionamento ácido produziu uma superfície com características topográficas e químicas diferentes quando comparadas às da superfície usinada. Além disso, observou-se que essas modificações de superfície afetaram de forma negativa a citocompatibilidade in vitro do cpTi como demonstrado pela inibição da proliferação celular e da expressão do fenótipo osteoblástico
Global wealth disparities drive adherence to COVID-safe pathways in head and neck cancer surgery
- Author
- Abbott Tom E F
- Abdallah E A
- Abdel-Galil K M A H
- Abdulwahed E A
- Abeloos J
- Acosta L
- Adamina Michel
- Ademuyiwa Adesoji O
- Adeyeye A A
- Adjeso T
- Agarwal Arnav
- Agarwal S
- Aguilera-Arévalo M
- Agyeman-Prempeh A
- Ahmed A
- Akornor E T
- Al assaf A
- Alakaloko Felix
- Alameer Ehab
- Albertsmeiers Markus
- Alderson Derek
- AlKharashi E
- Almasri M
- Alonso Lamberti L
- Alpert N
- Alser Osaid
- Alshaar Muhammad
- Alshareea E A
- Alshryda Sattar
- Alvarez M R
- Amankwaa W O
- Amin A
- Aning D
- Ansarin M
- Antoniadis K
- Antwi D A
- Apppiah-Thompson P
- Arikan A
- Arkadopoulos N
- Arkha Y
- Armstrong M
- Arnaud Alexis P
- Arrangoiz R
- Asceric R R
- Ashoush F M
- Augestad Knut Magne
- Ayasra Faris
- Aydemir L
- Aygun N
- Ayub B
- Azam M T
- Azevedo José
- Baietti A
- Baili E
- Baldini E
- Ballouhey Q
- Bankhead-Kendall Brittany K
- Baran E
- Barlow Emma
- Barnor I
- Barry C
- Basaran B
- Basaran B
- Bater M
- Batstone M
- Batstone Martin
- Batstone Martin
- Becerra GFC
- Becerril O S
- Bechri H
- Benkabbou A
- Benson Ruth A
- Benson Ruth A
- Bergonzani M
- Betz C S
- Bhangu Aneel
- Bhangu Aneel
- Biala M I
- Biel Juan Rey
- Biel Juan Rey
- Blanco-Colino Ruth
- Blaurock M
- Boccalatte L A
- Boehm A
- Bojicic J M
- Boucher S
- Brar Amanpreet
- Breen Kerry A
- Brennan P
- Bretherton Chris
- Brown L
- Bruzzaniti P
- Buarque Igor Lima
- Burgess C
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- Bywater Edward
- Böttcher A
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- Campisi G
- Carabias Hernandez A
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- Caruana Edward J
- Carvalho G B
- Casaril A
- Castro Silva J
- Catarzi L
- Chaar Mohammad
- Chakrabortee Sohini
- Chappity P
- Charalabopoulos A
- Chatziioannou I
- Chaudhry Daoud
- Cheng D
- Choi D
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- Christensen Peter
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- Consorti G
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- Hwang Shelley
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- Ibrahim A F
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- Ietrobon G
- İflazoğlu N
- Illezeau C N
- Ingrams D
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- Ionescu A
- Ionna F
- Irune E
- Isik A
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- Issahalq M D
- Jackson Richard
- Jariod-Ferrer U M
- Java K R
- Jelovac D
- Jenkinson Michael D
- Jiménez Carneros V
- Jiménez Miramón F J
- Jones Conor S
- Jones T M
- Jonker Pascal
- Joshi R
- Jover Navalón J M
- Kaafarani Haytham M A
- Kalfountzos C E
- Kamarajah Sivesh K
- Kar M
- Katre C
- Kaya T
- Keatley James M
- Kerawala C J
- Khatri Chetan
- Khaw Rachel A
- Khokhar M I
- King E
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- Kleeff J
- Knight Andrew
- Kokoropoulos P
- Kolias Angelos
- Konney A
- Kothari P
- Kovacevic B M
- Kowalski L
- Krdzic I D
- Kruijff Schelto
- Kucuk G
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- Kumar A
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- Laban S
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- Lallemant B
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- Landaluce Olavarria A
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- Lauretta M
- Lawani Ismail
- Lawday Samuel
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- Lee W
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- Lennon P
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- Leventoglu S
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- Lorena Maria Aguilera
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- Luke L
- Luksic I
- Löffler Markus W
- Maariën S
- Mace A D
- MacNeil D
- Madolo Maria Marta
- Maharaj D D
- Mahfoud M
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- Major Piotr
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- Minaya-Bravo Ana
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- Nixon I J
- Niziol R
- Ntirenganya Faustin
- Ntziovara A
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- Oliva R N L
- Olivos Maricarmen
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- Oussama Kacimi
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- Padilla Valverde D
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- Pata Francesco
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- Tabiri Stephen
- Tagliabue M
- Taioli E
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- Tiwari A R
- Tiwari Abhinav
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- Ugarte-Sierra B
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- Publication venue
- Publication date
- 01/01/2021
- Field of study
Peer reviewe
Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world
- Author
- Abad Pedro
- Abbara Suhny
- Abbasi Taimur
- Abbott Brian
- Abdel Aziz Islam Shawky
- Abdulla Jawdat
- Abikhzer Gad
- Abohashem Shady
- Abougabal Mahasen
- Abramson Sandra
- Abrihan Paz
- Acuña Arturo Romero
- Affandi Erwin
- Afzal Muhammad Shehzad
- Agolti Mariela
- Agranovich Svetlana
- Aguadé-Bruix Santiago
- Aguero Roberto Nicolas
- Ahmed Hassan Mohamed Ismail
- Ahmed Taghreed
- Akhter Afroza
- Al Dhuhli Humoud
- Al Kindi Faiza
- Al-Abboud Tarek
- Al-Bulushi Naeema
- Al-Mallah Mouaz
- Alak Maria del Carmen
- Alam Edison
- Alaoui Nadia Ismaili
- Alasnag Mirvat
- Albadr Amjed
- Albalooshi Batool
- Albano Domenico
- Alberguina Lucia Graciela
- Albernaz Siqueira Maria Helena
- Alexanderson-Rosas Erick
- Alfaro Ana
- Ali Mohamed Mandour
- Alkadhi Hatem
- Alkandari Faridah
- Allam Adel
- Allarakha Mohammad Aaftaab
- Almeida Augusto
- Almousalli Omar
- Alongi Pierpaolo
- Alonso Omar
- Alves Togni Paulo Henrique
- Alves Wilson Furlan
- Ananthasubramaniam Karthikeyan
- Anderson Jill
- Andrade Jose Henrique
- Andrade Luciana
- Angelidis George
- Anselmi Carlos
- Ansheles Alexey
- Araújo Roberta
- Archontaki Aikaterini
- Arnone Gaspare
- Arnous Samer
- Arnson Yoav
- Arroñada Guillermo
- Arturo Harold
- Asano Hiroshi
- Ascani Sebastian Perez
- Asfour Ahmed
- Askew Jeffrey
- Assadi Majid
- Astesiano Alfredo
- Astesiano Andrea
- Attanasio Lea
- Atyani Said
- Ayala Sandra
- Ayetey Harold
- Ayodele Tolulope
- Azevedo Guilherme
- Bagatin Elisa
- Bailly Matthieu
- Baldari Sergio
- Balmer-Swain Mallory
- Bang Ji-In
- Banthia Nilesh
- Bar-Shalom Rachel
- Barette Rene
- Baric Ana
- Barneveld Peter
- Barragan Adriana Puente
- Barragan Erika
- Barroso Asela
- Basavaraj Ashok Gangasandra
- Batinic Tonci
- Batista Juan Felipe
- Batyrkhanov Daultai
- Bauckneht Matteo
- Baugh Dainia
- Bayer Richard R.
- Bedi Punit
- Bejai Shereen
- Ben-Rais Nozha
- Benedek Imre
- Benedek Theodora
- Benitez Luis
- Benlabgaa Rabie
- Bennie George
- Benteo Pablo
- Beretta Mario
- Berman Daniel S.
- Bernheim Adam
- Bertelli Paolo
- Bester Ria
- Bettencourt Nuno
- Better Nathan
- Better Nathan
- Beuzeville Scott
- Bezerra Sabbrina
- Bhagat Jinendra Kumar
- Bhargava Rishi
- Bhat Vivek
- Bhatia Mona
- Bhatti Sabha
- Biancardi Rodrigo
- Bianco Francesco
- Bieging Erik
- Biggans Thomas
- Bittencourt Marcio Sommer
- Blanco Isabel
- Blanco Juan
- Blankstein Ron
- Blankstein Ron
- Bloom Stephen
- Blue Sean
- Bluemke David
- Bluemke David A.
- Boktor Raef
- Bom Henry
- Bonelli Juan Manuel
- Bonfiglioli Rachele
- Boni Roberto
- Borges Andressa
- Bouyoucef Salah
- Branch Kelley
- Brandão Simone
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- Brothers Jessica
- Bruno Andrea
- Bruno Isabella
- Bråten Anders Tjellaug
- Budoff Matthew
- Buechel Ronny Ralf
- Buga Klara
- Bularga Anda
- Bull Russell
- Bullock-Palmer Renée
- Burandt Angela
- Burg Samuel
- Burger Peter
- Burgul Rajesh
- Burke Floyd W.
- Bush Kelvin
- Busnardo Elena
- Bustos Jose Javier
- Butler Patrick
- Byrne Angela
- Bøttcher Morten
- Cabada Manuel
- Cabeda Estevan Vieira
- Cabrejas Raul
- Cabrera Antonio
- Cachero Jorge
- Cadena Alberto
- Caicedo Carlos
- Calcott Jennifer
- Califaretti Elena
- Camarero Alicia
- Camoni Luca
- Campisi Roxana
- Canal Maria Pedrera
- Candela Candace
- Canderoli Alejandro
- Canessa Jose
- Cantinho Guilhermina
- Cao Dianbo
- Capasso Elizabeth
- Carames Silvia
- Carnevale Aldo
- Carpenter John-Paul
- Carr Loretta
- Carrascosa Patrícia
- Carreira Lara
- Carvajal-Juarez Isabel
- Casoni Roberta
- Castro Bruno
- Castro Gabriel
- Castro Ricardo
- Casáns-Tormo Irene
- Cavalcante Joao
- Cavallo Armando Ugo
- Cavenaghi Giorgio
- Cendoya Oscar
- Cerci Rodrigo
- Cerci Rodrigo J.
- Ceriani Luca
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- Chan Virgil
- Chang Donald
- Chang Tien
- Chao Charles
- Chatterjee Saurav
- Chatziioannou Sofia
- Chatzizisis Yiannis
- Cheezum Michael
- Chen Jennifer
- Chen Marcus
- Chen Tiffany
- Cheung Stephen
- Chierichetti Franca
- Chimura Chimura Misato
- Chiocchi Marcello
- Cho Sang-Geon
- Choi Andrew
- Choi Andrew
- Choi Andrew D.
- Chong Woon
- Choudhury Partha
- Chow Benjamin
- Chowdekar Vijay Sai
- Christensen Mette
- Cittanti Corrado
- Clarcq James
- Cognigni Luciano Martin
- Cohen Yosef
- Cohen Yosef A.
- Coie Tchoyoson Lim
- Coles Duncan
- Collaud Carlos
- Collaud Carlos
- Colletta Mauro
- Concha Carmen
- Conti Umberto
- Cordero Ayreen
- Cortes Claudia
- Cortés Filiberto
- Cortés Violeta
- Cossu Alberto
- Courtis Javier
- Cragnolino Daniel
- Crim Matthew
- Cruz Eric
- Cuadra Teresa
- Cuellar-Calabria Hug
- Cunali Fernando
- Cuocolo Alberto
- Cury Roberto
- Cusack David
- Cuzzocrea Marco
- Dabreo Dominique
- Dai Xu
- Daicz Mariana
- Danciu Sorin
- Dantas Roberto
- Dariy Olga
- Datseris Ioannis
- Dautov Tairkhan
- de Amorim Fernandes Fernando
- De Boeck Bart
- De Carvalho Filipe Penna
- De La Peña Erasmo
- De La Vega Alejandro
- De Lorenzo Andrea
- De Macedo Filho Robson
- De Maria Silvia Teresa
- De Rimini Maria Luisa
- De Souza Thiago Ferreira
- De Vincentis Giuseppe
- Decter Bruce
- Del Giudice Eleonora
- Del Riego Horacio
- Del Torto Alberico
- Della Tommasina Veronica
- Deshpande Aparna
- Dettori Fernando
- Deux Jean-François
- Deviggiano Alejandro
- Dhruva Nimish
- Diaz Javier Lopez
- Djuraev Omoa
- Dobson Mark
- Doherty Neil
- Dondi Maurizio
- Dondi Maurizio
- Dorbala Sharmila
- Dorbala Sharmila
- Dougan John
- Doukky Rami
- Downie D'Arne
- Dragonetti Laura
- Drozdova Olga
- Dunbar Anjori
- Durmo Rexhep
- Duvall William
- Dwivedi Girish
- Edmond John
- Edwards Rachael
- Efros-Monsen Elen
- Einstein Andrew J.
- Einstein Andrew J.
- Elison Barry
- Ellis Chris
- Emami Farshad
- Embon Mario
- Engela Jean
- Engelbrecht Gerrit
- Engelmann Vaclav
- Enriquez Ruben Emilio
- Ensinas Jorge
- Erba Paola Anna
- Erthal Fernanda
- Escobar Manuel Valencia
- Escorza Velez Giovanni Alejandro
- Espeche Maria del Huerto Velazquez
- Esquitin Kerry
- Evangelista Laura
- Evbuomwan Osayande
- Faccio Fernando
- Facello Adolfo
- Fairbairn Timothy
- Faletti Riccardo
- Faragasso Evelina
- Faraggi Marc
- Farah Husam
- Farrugia Alexia
- Farsad Mohsen
- Fatima Shazia
- Fentanes Emilio
- Ferencik Maros
- Ferencik Maros
- Fernandes Fabio
- Fernandes Fabio
- Fernandes Juliano
- Ferrando Rodolfo
- Ferreira Antonio
- Ferro Paola
- Feuchtner Gudrun
- Fisher Daniel
- Fitzpatrick Daniel
- Flores Ana Camila
- Florimonte Luigia
- Flotats Albert
- Forsdahl Signe Helene
- Foster Cameron
- Fragkaki Christina
- Franceschi Maja
- Francis Roslyn
- Frantellizzi Viviana
- Frenkel Alex
- Friedrich Matthias
- Fringuelli Fabio Massimo
- Fuentes Cañamero Maria Eugenia
- Fuisz Tony
- Fujimoto Shinichiro
- Fujisue Koichiro
- Fukunaga Tomohisa
- Fukushima Yoshimitsu
- Fukuyama Kae
- Gagarina Nina
- Gaikwad Anand
- Gama-Moreno Manlio
- Gamboa Isabel Berrocal
- Gannon Michael
- Garai Ildiko
- Garashi Masoud
- Garcheva-Tsacheva Marina
- García María Elia
- Garg Ria
- Garofalo Diego
- Gastner Lori
- Gatti Marco
- Gaudiano Angela
- Georgoulias Panagiotis
- Geronazzo Ricardo
- Gerson Myron
- Gheysens Olivier
- Ghimire Ram Kumar
- Ghini Bruno
- Ghoshhajra Brian
- Gimelli Alessia
- Girijanandan Mahapatra Prof Dr
- Giubbini Raffaele
- Giuffrida Francesca
- Glaudemans Andor
- Gleeson Tadhg
- Goda Artan
- Goebel Benjamin
- Goebel Benjamin
- Goldberg Alan
- Goldner Brian
- Gomez Marie Rhiamar
- Gomez Sharon
- Goncalves Luiz
- Gong Lianggeng
- Gongxeka Harlem
- Gonza Natalia
- Gonzalez Carla
- Gonzalez Jorge
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- González Ulises
- González-Montecinos Alejandro Becerril
- Goodwin Bruce
- Gopalan Deepa
- Gore Rosco
- Gormsen Lars Christian
- Gottlieb Ilan
- Gracia-López Sandra
- Greenough Robert
- Grossman Gabriel Blacher
- Gräni Christoph
- Gulyaev Vsevolod Milyevich
- Gummow Alistair
- Gunawan Gani
- Gutierrez Villamil Claudia T.
- Gutierrez Goleat
- Gutierrez Lucas
- Gutierrez Yamile Marcos
- Gutierrez Yamile Marcos
- Guzzo Miguel Angel
- Guzzo Miguel Angel
- Gómez Lauchy Juan Manuel
- Habets Jesse
- Habouzit Vincent
- Hadlich Marcelo
- Hafez Mohammed Nassoh
- Hage Fadi
- Haidar Mohamad
- Haider Agha
- Haider Sofia
- Hamilton Mark
- Hamilton-Craig Christian
- Hamirani Yasmin
- Han Dan
- Hapkido Habusari
- Harbinson Mark
- Hartley Thomas
- Hasbak Philip
- Hasbani Victor
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- Hassan Mona
- Hassen Karen
- Hatfield Mallory
- Hawkins Carolyn
- Hawthorne Katie
- Heath Nicholas
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- Hernandez Phillip
- Hernández Gertrudis Sabatel
- Herrera Yariela
- Hess Søren
- Hidalgo Pablo
- Hidayat Basuki
- Hildre Dimmen Jenni-Mari
- Hill Gregory
- Hinterleitner Gerd
- Hirschfeld Cole B.
- Hirschfeld Cole B.
- Holdgaard Paw
- Homans Filip
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- Hua Shaw
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- Ialuna Salvatore
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- Kameoka Vinícius
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- Louw Lizette
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- Low Chen
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- Lu Bin
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- Marquez-Cabeza Juan Javier
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- Napier Kyle
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- Narula Jagat
- Narula Jagat
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- Nieves A López De Munaín Maria
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- Nolasco Roberto
- Nomura Cesar
- Norgaard Bjarne Linde
- Norikane Takashi
- Norton Carolina Bas
- Novoa Carlos
- Nunura Felix
- Nørgaard Bjarne Linde
- O'Brien Julie
- O'Rourke Edward
- O'Sullivan Patricia
- Obaldo Jerry
- Occleshaw Christopher
- Ohta Yasutoshi
- Oikonomou Anastasia
- Okarvi Subhani
- Okayama Satoshi
- Okizaki Atsutaka
- Oliveira Joao Bruno
- Ombati Kevin
- Onimode Yetunde
- Ornelas Mario
- Ortellado José
- Ortga Ramirez Jose Alberto
- Osman Medhat
- Otomi Yoichi
- Otsuka Hideki
- Ozair Ahmad
- Paar Maja Hrabak
- Pabon Luz
- Pacella Sara
- Padma Savenadia
- Paez Diana
- Paez Diana
- Paixao Eduardo
- Panagidis Christoforos
- Pandos George
- Parwani Purvi
- Parwani Purvi
- Parwani Purvi
- Pascual Thomas N. B.
- Pascual Thomas N. B.
- Pasquet Agnès
- Passen Edward
- Pastrana Davidson
- Patel Amit
- Patel Chetan
- Patel Dilip
- Patel Ravi
- Patel Shivani
- Patel Tapan
- Pathmaraj Kunthi
- Patil Pravin
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- Pawhay Christian Michael
- Pedras Felipe Villela
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- Persic Viktor
- Petrou Ioannis
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- Pianta Diego Bromfman
- Picard Christian
- Pineda Mauricio
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- Pliatsek Volodymyr
- Poksi Anne
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- Polsani Venkateshwar
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- Pomerantz Brian
- Pontone Gianluca
- Pool Stefan
- Porter Thomas
- Pospelov Viktor
- Possetti Priscila
- Poulter Rohan
- Prawiro Djoko
- Preciado-Anaya Andrés
- Preciado-Gutiérrez Óscar Ulises
- Premaratne Manuja
- Premprabha Teerapon
- Prentice Ryan
- Prior David
- Prior John O.
- Probst Stephan
- Proffit Franck
- Prpic Marina
- Pubul-Nuñez Virginia
- Pugliese Francesca
- Pujol Maria Paula
- Pulizzi Sabina
- Punda Ante
- Pursnani Amit
- Pynda Yaroslav
- Pynda Yaroslav
- Quartuccio Natale
- Quinon Alvin
- Quinta Mayra
- Rabbat Mark
- Radzinschi Alejandro
- Raggi Paolo
- Raggi Paolo
- Raimondi Gustavo
- Rajbanshi Bijoy
- Rajvong Sonexay
- Ramamurti Suresh
- Ramkumar Prasad Guntur
- Rampin Lucia
- Ramírez Nelsy Gonzalez
- Randazzo Michael
- Randazzo Michael J.
- Ranser Sara
- Rawashdeh Mohammad
- Rayo Madrid Juan Ignacio
- Redruello Marcela
- Regaieg Hamza
- Reichmuth Luise
- Repasos Evangelos
- Rey Cristina Rodríguez
- Riaz Musab
- Ricci Fabrizio
- Rich Florence
- Ridley Lloyd
- Robinson Austin
- Robles Kim
- Rocha Ricardo
- Rochela Luis
- Rodrigues Alfredo
- Rodrigues Carlos
- Rodriguez Daniel Calderon
- Rodríguez Cesar
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- Rodríguez Matías
- Roelants Veronique
- Rofe Christopher
- Roifman Idan
- Rojas Juan Carlos
- Romantini Leila
- Romero Romina Lorena
- Rominger Axel
- Roque Vanegas Hector Bladimir
- Rorie Mark
- Rosales Uvera Sandra Graciela
- Rossini Pierluigi
- Rostami Maryam Tajik
- Rovaletti Federico
- Rozikhodjaeva Gulnora
- Rubini Giuseppe
- Ruiz Diego
- Ruiz Joaquín
- Rumberger John
- Russell Raymond
- Russo Vincenzo
- Rutherford Natalie
- Ryzhkova Daria
- Ríos Raúl Araujo
- Rønnow Sand Niels Peter
- Saadullah Mohammad
- Sabharwal Nikant
- Sabra Philip
- Sacchetti Gian Mauro
- Sadler Diego
- Saifullina Guzaliya
- Saito Masaki
- Sakanyan Mari
- Sakata Sakata Yasushi
- Salehi Hamid
- Salobir Barbara Gužic
- Sambuceti Gianmario
- Samuel Anthony
- San Miguel Lucas
- Sanches Adelina
- Sandoval Sigelinda
- Santana Sara
- Sara da Silva Leonardo
- Sarai Masayoshi
- Saranovic Dragana Sobic
- Sarda-Mantel Laure
- Sasse Alexander
- Sato Daisuke
- Satyr Maryna
- Saunders Connor
- Saxena Sudhir
- Sayman Haluk
- Sazonova Svetlana
- Scarano Massimo
- Scarlett Luke
- Schemmer Mary
- Schmidt Erzsébet
- Schneider Roman P.
- Schoepf U. Joseph
- Schofield Rebecca
- Scholte Arthur
- Scholtens Asbjørn
- Scholtz Leonie
- Schvartzman Paulo
- Sciagrà Roberto
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- Sekar Ramkumar
- Sellem Ali
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- Sengupta Shantanu
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- Sergienko Vladimir
- Sergienko Vladimir
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- Shaaban Mahmoud
- Shah Nishant
- Shah Nishant R.
- Shah Samir
- Shalev Aryeh
- Shanbhag Sujata
- Sharma Gaurav
- Sharma Naveen
- Shaw Leslee J.
- Shaw Leslee J.
- Shayani Steven
- Shetty Deepa
- Shiozaki Afonso
- Shiraishi Shinya
- Shirani Jamshid
- Shirka Ervina
- Shivaram Pushpa
- Shrestha Ganesh
- Shulman Jonathan
- Shurupova Irina
- Sierra-Galan Lilia M.
- Sierra-Galan Lilia M.
- Sigman Steven
- Silva Fábio Martins
- Simanek Milan
- Simon Mitch
- Simonsson Magnus
- Singh Bhanupriya
- Singh Santosh
- Sinitsyn Valentin
- Siqueira Cristiano
- Siu Silvia
- Slart Riemer
- Slim Ahmad
- Small Gary
- Smanio Paola
- Smith Alexandra
- Smith David
- So Young
- Soares Carlos Eduardo
- Soeriadi Erwin Affandi
- Solanki Vijay
- Solari Lucrecia
- Soldat-Stankovic Valentina
- Soli Idrissa Adamou
- Soman Prem
- Sood Aditya
- Sood Ashwani
- Sperandio Massimiliano
- Spiro Bernardo
- Srichai-Parsia Monvadi Barbara
- Stan Claudiu Adrian
- Stankovic Sinisa
- Stanton Tony
- Stavrou Petros
- Stefanelli Antonella
- Steffensen Rolf
- Strada Bruno
- Streeter James
- Strouhal Peter
- Stuart Murch
- Stubbs Michael
- Subedi Deepak
- Sueldo Claudio Pereyra
- Sun Kai
- Suwa Yoshinobu
- Swainson Ian
- Syawaluddin Hilman
- Syed Ghulam
- Szilveszter Balint
- T Albert
- Tacher Vania
- Tag Naima
- Takanami Kentaro
- Takehana Kazuya
- Taki Junichi
- Taleb Sara
- Tamaki Nagara
- Tandon Vikas
- Tang Gongshun
- Tang Jeanelle Margareth
- Taniguchi Yasuyo
- Taubman Kim
- Tawakol Ahmed
- Taylor Andrew
- Tecson Bettina
- Teragawa Hiroki
- Theng Youdaline
- Thientunyakit Tanyaluck
- Thimister Paul
- Thomas Dustin
- Thomas Paul
- Thomassen Anders
- Thompson Randall
- Thu Phyo Si
- To Andrew
- Tomas Miguel Santaularia
- Tomizawa Nobuo
- Topping William
- Torbet Tara
- Torreao Jorge
- Torres Rafael
- Traverso Sonia
- Traverzo Sonia Simona
- Trifonova Tatjana
- Trinidad Desiree
- Trivedi Adwait
- Tsujita Kenichi
- Tweed Katharine
- Udugama Chandraguptha
- Uellendahl Marly
- Ullery Shawn
- Umeji Kyoko
- Unger Steven
- Unzek Samuel
- Upton Anthony
- Uretsky Seth
- Uson Kristine Joy
- Ussov Wladimir Yurievich
- Uusitalo Valtteri
- Uy Mila
- Vajauskas Donatas
- Vakhromeeva Margarita
- Valiullina Nailya
- Vallejo Enrique
- Valles Mario
- Vallurupalli Srikanth
- Vallée Jean-Paul
- Valsamaki Pipitsa
- Vamadevan Shankar
- Van Asperen Erik-Jan
- Van De Heyning Caroline M.
- Van Gaal William
- Van Pelt Niels
- Vangu Mboyo
- Vargas Luis Salazar
- Vasquez Andres
- Vavlukis Marija
- Velez Mayra Sanchez
- Veltman Niels
- Ventroni Guido
- Vergel Damiana
- Verjans Johan
- Verma Atul
- Verma Vikas
- Verschure Derk
- Veríssimo Otávia
- Villines Todd C.
- Villines Todd C.
- Vitola Joao V.
- Vitola Joao V.
- Vondrak Andrej
- Voutnis Demetrius
- Vuuren Magritha Jv
- Várady Edit
- Vázquez Manuel Castillo
- Wagenaar Nils
- Wakabayashi Yasushi
- Waller Alfonso
- Waltrick Roberto
- Wang Ellen
- Wang Jian
- Wang Ximing
- Wang Yifan
- Wang Yining
- Wang Zhao-Qian
- Ward Parker
- Wayne Victor
- Weihmuller Juan Sebastian
- Weir-Mccall Jonathan
- Weiss Konrad
- Weissman Gaby
- Wesbey George
- White James
- White Kelly
- Williams Michelle C.
- Williams Michelle C.
- Wilson Peter
- Winchester David
- Winchester David
- Wolcan Juan
- Wolinsky David
- Won Kyoung Sook
- Wong David
- Wong Kirby
- Wu Jiang
- Wu Zhifang
- Xia Liming
- Xiao Jiangxi
- Xu Lei
- Xu Zhuoran
- Yamada Shinichiro
- Yamazaki Shinya
- Yang Youyou
- Yew Min Sen
- Yin Wu
- Yoneyama Tatsuya
- Yost Sandra
- Young Calum
- Younger John
- Younis Muhammad Numair
- Yu Jianqun
- Yuan Li
- Zaid Eed Abu
- Zakavi Seyed Rasoul
- Zapparoli Marcello
- Zavadovsky Konstantin
- Zeffiro Susana
- Zeidán Nahla
- Zerahn Bo
- Zgaljardic Michael
- Zhang Longjiang
- Zhang Tong
- Zhang Xiaoli
- Zhang Yong-Gao
- Zhu Li
- Zhuravlev Kirill
- Zoboli Stefania
- Zukotynski Katherine
- Zuluaga Alejandro
- Øvrehus Kristian Altern
- Štalc Monika
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic.
Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality.
Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States.
Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis.
Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection
Multi-messenger observations of a binary neutron star merger
- Author
- Aab A
- Aartsen MG
- Abbott BP
- Abbott R
- Abbott TD
- Abbott TMC
- Abdalla H
- Abe F
- Abeysekara AU
- Abramo LR
- Abramowski A
- Abreu P
- Acernese F
- Acero F
- Ackermann M
- Ackley K
- Ackley K
- Adams C
- Adams J
- Adams SM
- Adams T
- Addesso P
- Adhikari RX
- Adya VB
- Affeldt C
- Afrough M
- Agarwal B
- Agathos M
- Agatsuma K
- Aggarwal N
- Aglietta M
- Agliozzo C
- Agudo I
- Aguiar OD
- Aguilar JA
- Aharonian F
- Ahlers M
- Ahrens M
- Aiello L
- Ain A
- Ajith P
- Akras S
- Al Samarai I
- Albert A
- Albert A
- Albuquerque IFM
- Albury JM
- Alcaniz JS
- Alexander KD
- Alfaro R
- Alighieri S Di Serego
- Allam S
- Allekotte I
- Allen B
- Allen G
- Allison J
- Allison JR
- Allocca A
- Almela A
- Altin PA
- Altmann D
- Alvarez C
- Alvarez JD
- Alvarez M Dovale
- Alvarez-Muiz J
- Amati L
- Amato A
- An T
- Ananyeva A
- Anastasi GA
- Anchordoqui L
- Andeen K
- Anderson JP
- Anderson SB
- Anderson T
- Anderson WG
- Andrada B
- Andre M
- Andreoni I
- Andreoni I
- Andringa S
- Angelova SV
- Anghinolfi M
- Angner EO
- Angus CR
- Annis J
- Ansseau I
- Antier S
- Anton G
- Antonelli LA
- Antonelli LA
- Anupama GC
- Aoki K
- Aoki W
- Appert S
- Aptekar RL
- Arai K
- Arakawa M
- Aramo C
- Araya MC
- Arcavi I
- Arceo R
- Ardid M
- Areeda JS
- Aresu G
- Argan A
- Argelles C
- Arnaud N
- Array LWA Long Wavelength
- Array MWA Murchison Widefield
- Arrieta M
- Arsene N
- Arteaga-Velzquez JC
- Artola R
- Arun KG
- Asakura Y
- Asaoka Y
- Ascenzi S
- Ashall C
- Ashley MCB
- Ashton G
- Asorey H
- Assis P
- Ast M
- Aston SM
- Astone P
- Atallah DV
- ATLAS
- Atwood WB
- Aubert J-J
- Aubert P
- Aublin J
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- Cowen DF
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- Fukazawa Y
- Fulda P
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- Zimmerman AB
- Zimmermann B
- Zimnukhov DS
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- Zucker ME
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- Zweizig J
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- Publication venue
- 'American Astronomical Society'
- Publication date
- 01/01/2017
- Field of study
On 2017 August 17 a binary neutron star coalescence candidate (later designated GW170817) with merger time 12:41:04 UTC was observed through gravitational waves by the Advanced LIGO and Advanced Virgo detectors. The Fermi Gamma-ray Burst Monitor independently detected a gamma-ray burst (GRB 170817A) with a time delay of ~1.7 s with respect to the merger time. From the gravitational-wave signal, the source was initially localized to a sky region of 31 deg2 at a luminosity distance of 40+8-8 Mpc and with component masses consistent with neutron stars. The component masses were later measured to be in the range 0.86 to 2.26 Mo. An extensive observing campaign was launched across the electromagnetic spectrum leading to the discovery of a bright optical transient (SSS17a, now with the IAU identification of AT 2017gfo) in NGC 4993 (at ~40 Mpc) less than 11 hours after the merger by the One- Meter, Two Hemisphere (1M2H) team using the 1 m Swope Telescope. The optical transient was independently detected by multiple teams within an hour. Subsequent observations targeted the object and its environment. Early ultraviolet observations revealed a blue transient that faded within 48 hours. Optical and infrared observations showed a redward evolution over ~10 days. Following early non-detections, X-ray and radio emission were discovered at the transient’s position ~9 and ~16 days, respectively, after the merger. Both the X-ray and radio emission likely arise from a physical process that is distinct from the one that generates the UV/optical/near-infrared emission. No ultra-high-energy gamma-rays and no neutrino candidates consistent with the source were found in follow-up searches. These observations support the hypothesis that GW170817 was produced by the merger of two neutron stars in NGC4993 followed by a short gamma-ray burst (GRB 170817A) and a kilonova/macronova powered by the radioactive decay of r-process nuclei synthesized in the ejecta
The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study
- Author
- Abadia M
- Abassy J
- Abate E
- Abbott Tom EF
- Abdelaal Samir A
- Abdeldayem H
- Abdelkabir M
- Abdelsamed A
- Abdulwahed E
- Abiyere H
- Abou Chaar MK
- Abukhalaf SA
- Abukhalaf Sadi
- Adamina Michel
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji O
- Adeyeye A
- Adisa Adewale
- Afzal MF
- Agarwal Arnav
- Aggarwal M
- Agnes A
- Agostini C
- Agrawal A
- Agrawal N
- Agresta F
- Aguiar Junior S
- Ahmed A
- Ahmed K
- Ahmed Nafees R
- Ahmed Z
- Ahn JH
- Aime A
- Akhtar N
- Akkulak Murat
- Akrivou D
- Al Abdallah M
- Al Riyami S
- Al Sayed M
- Al-Masri M
- Al-Najjar H
- Al-Slaibi I
- Alaa S
- Alakaloko Felix
- Alameer Ehab
- Alamri Alex
- Alawneh F
- Albertsmeier M
- Albertsmeier Markus
- Alderson Derek
- Aldokali N
- Alemanno G
- Alfieri S
- Algallai M
- Ali AA
- Alkadiki Ghadah Z
- Almaadany Faraj S
- Almeida AC
- Almeida-Reis R
- Almezghwi H
- Almond Max
- Alrahawy M
- Alser Osaid
- Alshaar Muhammad
- Alshareea E
- Alshareef K
- Alshryda Sattar
- Alsoufi A
- Altamirano Riquoir C
- Altomare DF
- Altomi I
- Alurralde C
- Alvarez MR
- Alvi A
- Alwarfly S
- AlZAEDE S
- Alzeerelhouseini IAH
- Amaral MJ
- Amira G
- Amorim E
- Amrani L
- Anania G
- Anastasi A
- Andrade Kam da Silva A
- Andrade R
- Annessi V
- Annicchiarico A
- Antonakis P
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- Tabiri Stephen
- Tactuk N
- Taddei A
- Taibi A
- Talaat M
- Tamini N
- Tammaro P
- Tan JA
- Tanzanu M
- Tartaglia D
- Tasis N
- Tavares F
- Tawheed A
- Teh C
- Teixeira J
- Teixeira M
- Testa V
- Thanapal MR
- Thekinkattil Dinesh
- Theodosopoulos T
- Thian A
- Tirloni L
- Tirotta Fabio
- Tojal A
- Tolani MA
- Tom K
- Tonini V
- Tooulias A
- Townen Philip
- Townend D
- Townend Philip
- Travaglio E
- Tribillon E
- Tropeano FP
- Tsiaoussis I
- Tsoulfas G
- Tsoulfas Georgios
- Tucci R
- Tufo A
- Turk K
- Turri G
- Tzedakis S
- Tzovaras G
- Ugolini G
- Umair M
- Umar A
- Urbani A
- Usai A
- Uzunoglu FG
- Vaccarella G
- Vale R
- Valenzuela J
- Vallance Abigail
- Van de Putte D
- Van den Eynde J
- Van den Eynde R
- van der Plas Willemijn
- Van Heinsbergen M
- Van Nieuwenhove Y
- Van Ramshorst G
- van Ramshorst Gabrielle H
- Varghese Chris
- Vasey C
- Vassiliu P
- Vaz S
- Vaz-Pereira R
- Veetil Kannummal S
- Vendrame C
- Venskutonis D
- Vergari R
- Vernon L
- Vescio G
- Vezakis A
- Vidya Raghavan
- Vieira A
- Vieira B
- Vignali A
- Vignotto C
- Vilar-Compte D
- Vimalachandran Dale
- Vimalchandra Dale
- Violante T
- Vishnoi JR
- Vitali A
- Vo UG
- Volpin E
- Von Papen M
- Vovola F
- Waldron A
- Walker P
- Walkes K
- Wani R
- Waqar SH
- Warren Oliver J
- Watson E
- Wedderburn Duane
- Weitz J
- Welsch T
- Werner J
- Whelan M
- Wilkins Alex
- Willaert W
- Wimmer A
- Winter D
- Winter Stuart C
- Wong MP
- Wood M
- Wrigh Naomi
- Wullschleger M
- Xavier R
- Xenaki S
- Xynos E
- Yadev I
- Yang W
- Ye G
- Yezzaji H
- Yiallourou A
- Yousof EA
- Yunus Mohd MF
- Yurttas C
- Zakaria AD
- Zakaria Z
- Zambon M
- Zanus G
- Zatecky J
- Zelic M
- Zerbib P
- Zervas K
- Zese M
- Zhang H
- Zizzo M
- Zmora O
- Zografos C
- Zonta S
- Zourntou S
- Publication venue
- 'Royal College of Obstetricians & Gynaecologists (RCOG)'
- Publication date
- 01/06/2022
- Field of study
AIM: The SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery. METHODS: This was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January-April 2020). Surgical delay was defined as an operation taking place more than 4 weeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin. RESULTS: Overall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4 weeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, P = 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, P < 0.001). After adjustment, delay was not associated with a lower rate of complete resection (OR 1.18, 95% CI 0.90-1.55, P = 0.224), which was consistent in elective patients only (OR 0.94, 95% CI 0.69-1.27, P = 0.672). Longer delays were not associated with poorer outcomes. CONCLUSION: One in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease
Base de datos de abejas ibéricas
- Author
- Aguado-Martín Luis Oscar
- Alomar David
- Arista Montserrat
- Arroyo-Correa Blanca
- Asís Josep D.
- Azpiazu Celeste
- Bartomeus Ignasi
- Baños-Picón Laura
- Beja Pedro
- Boieiro Mário
- Borges Paulo A. V.
- Carvalheiro Luisa
- Carvalho Rafael
- Casimiro-Soriguer Ramón
- Castro Silvia
- Collado Miguel Ángel
- Costa Joana
- Cross Ian
- De la Rúa Pilar
- de Pablos Luis MIguel
- de Paz Víctor
- Díaz-Calafat Joan
- Ferrero Victoria
- Gaspar Hugo
- Ghisbain Guillaume
- González Bornay Guillermo
- González-Estévez Miguel Ángel
- Gómez José María
- Gómez-Martínez Carmelo
- Heleno Ruben
- Herrera Jose M.
- Hormaza Jose I.
- Iriondo Jose M.
- Kuhlmann Michael
- Laiolo Paola
- Lanuza Jose B.
- Lara-Romero Carlos
- Loureiro João
- Lázaro Amparo
- López-Angulo Jesús
- López-Núñez Francisco A.
- Magrach Ainhoa
- Martínez-López Vicente
- Martínez-Núñez Carlos
- Michez Denis
- Miñarro Marcos
- Molina Francisco P.
- Montero-Castaño Ana
- Moreira Bruno
- Morente-López Javier
- Noval Fonseca Nacho
- Núñez Carbajal Alejandro
- Obeso José Ramón
- Ornosa Concepción
- Ortiz-Sánchez Francisco Javier
- Pareja Bonilla Daniel
- Patiny Sébastien
- Penado Andreia
- Picanço Ana
- Ploquin Emilie F.
- Rasmont Pierre
- Rego Carla
- Rey Pedro J.
- Ribas-Marquès Elisa
- Roberts Stuart P.M.
- Rodriguez Marta
- Rosas-Ramos Natalia
- Santamaría Silvia
- Sánchez Ana M.
- Tobajas Estefanía
- Tormos José
- Torres Félix
- Trillo Alejandro
- Valverde Javier
- Vilà Montserrat
- Viñuela Elisa
- Wood Thomas J.
- Álvarez Fidalgo Piluca
- Álvarez-Fidalgo Marián
- Publication venue
- 'Asociacion Española de Ecologia Terrestre (AEET)'
- Publication date
- 01/01/2022
- Field of study
Las abejas son un grupo extremadamente diverso con más de 1000 especies descritas en la península ibérica. Además, son excelentes polinizadores y aportan numerosos servicios ecosistémicos fundamentales para la mayoría de ecosistemas terrestres. Debido a los diversos cambios ambientales inducidos por el ser humano, existen evidencias del declive de algunas de sus poblaciones para ciertas especies. Sin embargo, conocemos muy poco del estado de conservación de la mayoría de especies y de muchas de ellas ignoramos cuál es su distribución en la península ibérica. En este trabajo presentamos un esfuerzo colaborativo para crear una base de datos de ocurrencias de abejas que abarca la península ibérica e islas Baleares que permitirá resolver cuestiones como la distribución de las diferentes especies, preferencia de hábitat, fenología o tendencias históricas. En su versión actual, esta base de datos contiene un total de 87 684 registros de 923 especies recolectados entre 1830 y 2022, de los cuales un 87% presentan información georreferenciada. Para cada registro se incluye información relativa a la localidad de muestreo (89%), identificador y colector de la especie (64%), fecha de captura (54%) y planta donde se recolectó (20%). Creemos que esta base de datos es el punto de partida para conocer y conservar mejor la biodiversidad de abejas en la península ibérica e Islas Baleares. Se puede acceder a estos datos a través del siguiente enlace permanente: https://doi.org/10.5281/zenodo.6354502ABSTRACT: Bees are a diverse group with more than 1000 species known from the Iberian Peninsula. They have increasingly received special attention due to their important role as pollinators and providers of ecosystem services. In addition, various rapid human-induced environmental changes are leading to the decline of some of its populations. However, we know very little about the conservation status of most species and for many species, we hardly know their true distributions across the Iberian Peninsula. Here, we present a collaborative effort to collate and curate a database of Iberian bee occurrences to answer questions about their distribution, habitat preference, phenology, or historical trends. In total we have accumulated 87 684 records from the Iberian Peninsula and the Balearic Islands of 923 different species with 87% of georeferenced records collected between 1830 and 2022. In addition, each record has associated information such as the sampling location (89%), collector and person who identified the species (64%), date of the capture (54%) and plant species where the bees were captured (20%). We believe that this database is the starting point to better understand and conserve bee biodiversity in the Iberian Peninsula. It can be accessed at: https://doi.org/10.5281/zenodo.6354502Esta base de datos se ha realizado con la ayuda de los proyectos EUCLIPO (Fundação para a Ciência e a Tecnologia, LISBOA-01-0145-FEDER-028360/EUCLIPO) y SAFEGUARD (ref. 101003476 H2020 -SFS-2019-2).info:eu-repo/semantics/publishedVersio
SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway
- Author
- Aanensen David M.
- Abraham Priyanka
- Abudahab Khalil
- Adams Alexander
- Adams Helen
- Adele Sandra
- Afifi Safiah
- Aggarwal Dinesh
- Ahmad Shazaad S. Y.
- Aigrain Louise
- Alcolea-Medina Adela
- Alikhan Nabil-Fareed
- Allara Elias
- Amato Roberto
- Angyal Adrienn
- Annett Tara
- Ansari M. Azim
- Aplin Stephen
- Ariani Cristina V.
- Asad Hibo
- Asamaphan Patawee
- Ash Amy
- Ashfield Paula
- Ashford Fiona
- Ashraf Shirin
- Atkinson Laura
- Attwood Stephen W.
- Auckland Cressida
- Austin James
- Aydin Alp
- Baker David J.
- Baker Paul
- Balcazar Carlos E.
- Ball Jonathan
- Barnes Eleanor
- Barrett Jeffrey C.
- Barrow Magdalena
- Barton Edward
- Bashton Matthew
- Bassett Andrew R.
- Batra Rahul
- Baxter Chris
- Bayzid Nadua
- Beaver Charlotte
- Beckett Angela H.
- Beckwith Shaun M.
- Bedford Luke
- Beer Robert
- Beggs Andrew
- Bellis Katherine L.
- Berry Louise
- Bertolusso Beatrice
- Best Angus
- Betteridge Emma
- Bibby David
- Bicknell Kelly
- Binns Debbie
- Birchley Alec
- Bird Paul W.
- Bishop Chloe
- Blacow Rachel
- Blakey Victoria
- Blane Beth
- Bolt Frances
- Bonfield James
- Bonner Stephen
- Bonsall David
- Boswell Tim
- Bosworth Andrew
- Bourgeois Yann
- Bouzidi Kate El
- Boyd Olivia
- Bradley Declan T.
- Breen Cassie
- Bresner Catherine
- Breuer Judith
- Bridgett Stephen
- Bronner Iraad F.
- Brooks Ellena
- Broos Alice
- Brown Anthony
- Brown Julianne R.
- Bucca Giselda
- Buchan Sarah L.
- Buck David
- Bull Matthew
- Burns Phillipa J.
- Burton-Fanning Shirelle
- Byaruhanga Timothy
- Byott Matthew
- Campbell Sharon
- Cantoni Diego
- Carabelli Alessandro M.
- Cargill James S.
- Carlile Matthew
- Carvalho Sílvia F.
- Casey Anna
- Castigador Anibolina
- Catalan Jana
- Chalker Vicki
- Chaloner Nicola J.
- Chand Meera
- Chappell Joseph G.
- Charalampous Themoula
- Chatterton Wendy
- Chaudhry Yasmin
- Churcher Carol M.
- Clark Gemma
- Clarke Phillip
- Cogger Benjamin J.
- Cole Kevin
- Collins Jennifer
- Colquhoun Rachel
- Connor Thomas R.
- Cook Kate F.
- Coombes Jason
- Corden Sally
- Cormie Claire
- Cortes Nicholas
- Cotic Marius
- Cotton Seb
- Cottrell Simon
- Coupland Lindsay
- Cowton Vanessa
- Cox Alison
- Cox MacGregor
- Craine Noel
- Crawford Liam
- Cross Aidan
- Crown Matthew R.
- Crudgington Dorian
- Cumley Nicola
- Curran Martin D.
- Curran Tanya
- Cutino-Moguel Teresa
- da Silva Filipe Ana
- da Silva Filipe Ana
- Dabrera Gavin
- Darby Alistair C.
- Davidson Rose K.
- Davies Alisha
- Davies Robert M.
- Davis Chris
- Davis Thomas
- de Angelis Daniela
- De Lacy Elen
- De Lorenzo Giuditta
- de Oliveira Martins Leonardo
- de Silva Thushan
- de Silva Thushan I.
- Debebe Johnny
- Deeks Alexandra
- Denton-Smith Rebecca
- Dervisevic Samir
- Dewar Rebecca
- Dey Jayasree
- Dias Joana
- Dobie Donald
- Dorman Matthew J.
- Downing Fatima
- Driscoll Megan
- du Plessis Louis
- Duckworth Nichola
- Dunachie Susanna
- Dunachie Susanna
- Duncan Christopher
- Durham Jillian
- Eastick Kirstine
- Easton Lisa J.
- Eccles Richard
- Edgeworth Jonathan
- Edwards Sue
- Eldirdiri Sahar
- Ellaby Nicholas
- Elliott Scott
- Eltringham Gary
- Ensell Leah
- Erkiert Michelle J.
- Essex Sarah
- Evans Cariad
- Evans Johnathan M.
- Everson William
- Fairley Derek J.
- Fallon Karlie
- Fanaie Arezou
- Farr Ben W.
- Fearn Christopher
- Feltwell Theresa
- Ferguson Lynne
- Fina Laia
- Flaviani Flavia
- Fleming Vicki M.
- Forrest Sally
- Foster-Nyarko Ebenezer
- Foulkes Benjamin H.
- Foulser Luke
- Fragakis Mireille
- Frampton Dan
- Francois Sarah
- Fraser Christophe
- Freeman Timothy M.
- Fryer Helen
- Fuchs Marc
- Fuller William
- Furnon Wilhelm
- Gajee Kavitha
- Galai Katerina
- Gallagher Abbie
- Gallagher Eileen
- Gallagher Michael D.
- Gallis Marta
- Gaskin Amy
- Gatica-Wilcox Bree
- Geidelberg Lily
- Gemmell Matthew
- Georgana Iliana
- George Ryan P.
- Gifford Laura
- Gilbert Lauren
- Girgis Sophia T.
- Glaysher Sharon
- Goldstein Emily J.
- Golubchik Tanya
- Gomes Andrea N.
- Gonçalves Sónia
- Goodfellow Ian G.
- Goodwin Scott
- Goudarzi Salman
- Gourtovaia Marina
- Graham Clive
- Graham Lee
- Grant Paul R.
- Green Angie
- Green Luke R.
- Greenaway Jane
- Gregory Richard
- Grove Joe
- Guest Martyn
- Gunson Rory
- Gunson Rory N.
- Gupta Ravi K.
- Gutierrez Bernardo
- Haldenby Sam T.
- Hamilton William L.
- Hansford Samantha E.
- Haque Tanzina
- Harris Kathryn A.
- Harrison Ewan M.
- Harrison Ian
- Hart Jennifer
- Hartley John A.
- Harvey Matthew
- Harvey William T.
- Harvey William T.
- Hassan-Ibrahim Mohammed O.
- Haughney John
- Heaney Judith
- Helmer Thomas
- Henderson John H.
- Hesketh Andrew R.
- Hey Jessica
- Heyburn David
- Higginson Ellen E.
- Hill Jack D.
- Hill Verity
- Hilson Rachel A.
- Hilvers Ember
- Holden Matthew T. G.
- Holden Matthew T. G.
- Holland Poppy
- Hollis Amy
- Holmes Alison H.
- Holmes Christopher W.
- Holmes Nadine
- Hopes Richard
- Hornsby Hailey R.
- Hosmillo Myra
- Houlihan Catherine
- Howson-Wells Hannah C.
- Hsu Sharon N.
- Hubb Jonathan
- Huckson Hannah
- Hughes Joseph
- Hughes Joseph
- Hughes Margaret
- Hughes Warwick
- Hutchings Stephanie
- Idle Giles
- Illingworth Chris J.
- Impey Robert
- Irish-Tavares Dianne
- Iturriza-Gomara Miren
- Izuagbe Rhys
- Jackson Ben
- Jackson Chris
- Jackson David K.
- Jackson Kathryn A.
- Jackson Leigh M.
- Jahun Aminu S.
- James Keith
- James Victoria
- Jeanes Christopher
- Jeffries Aaron R.
- Jeremiah Sarah
- Jermy Andrew
- John Michaela
- Johnson Kate
- Johnson Rob
- Johnston Ian
- Jones Christopher R.
- Jones Hannah
- Jones Neil
- Jones Owen
- Jones Sophie
- Joseph Amelia
- Judges Sarah
- Kay Gemma L.
- Kay Sally
- Keatley Jon-Paul
- Keeley Alexander J.
- Kele Beatrix
- Kenyon Anita
- Kermack Leanne M.
- Khakh Manjinder
- Kidd Stephen P.
- Killough Nicholas F.
- Kimuli Maimuna
- Kirk Stuart
- Kitchen Christine
- Kitchman Katie
- Klenerman Paul
- Klenerman Paul
- Knight Bridget A.
- Koshy Cherian
- Kraemer Moritz U. G.
- Kronsteiner Barbara
- Kumziene-Summerhayes Sara
- Kwiatkowski Dominic
- Lackenby Angie
- Laing Kenneth G.
- Lampejo Temi
- Langford Cordelia F.
- Lavin Deborah
- Lawton Andrew I.
- Le-Viet Thanh
- Lee David
- Lee Jack C. D.
- Lensing Stefanie V.
- Leonard Steven
- Levett Lisa J.
- Lewis Jonathan
- Lewis Kevin
- Liddle Jennifier
- Liggett Steven
- Lillie Patrick J.
- Lindsey Benjamin B.
- Lister Michelle M.
- Livett Rich
- Lo Stephanie
- Logan Nicola
- Loman Nicholas J.
- Loose Matthew W.
- Louka Stavroula F.
- Loveson Katie F.
- Lowdon Sarah
- Lowe Hannah
- Lowe Helen L.
- Lucaci Anita O.
- Ludden Catherine
- Lynch Jessica
- Lyons Ronan A.
- Lythgoe Katrina
- Machin Nicholas W.
- MacIntyre-Cockett George
- Mack Andrew
- Macklin Ben
- Maclean Alasdair
- MacLean Oscar A.
- Macnaughton Emily
- Madona Pinglawathee
- Maes Mailis
- Maftei Laurentiu
- Mahanama Adhyana I. K.
- Mahungu Tabitha W.
- Mair Daniel
- Maksimovic Joshua
- Malone Cassandra S.
- Maloney Daniel
- Manali Maria
- Manesis Nikos
- Manley Robin
- Mantzouratou Anna
- Marchbank Angela
- Mariappan Arun
- Martincorena Inigo
- Martinez Nunez Rocio T.
- Mather Alison E.
- Maxwell Patrick
- Mayhew Megan
- Mbisa Tamyo
- McCann Clare M.
- McCarthy Shane A.
- McCluggage Kathryn
- McClure Patrick C.
- McCrone J. T.
- McHugh Martin P.
- McKenna James P.
- McKerr Caoimhe
- McManus Georgina M.
- McMurray Claire
- McMurray Claire L.
- McNally Alan
- Meadows Lizzie
- Medd Nathan
- Megram Oliver
- Menegazzo Mirko
- Merrick Ian
- Michell Stephen L.
- Michelsen Michelle L.
- Mirfenderesky Mariyam
- Mirza Jeremy
- Miskelly Julia
- Moles-Garcia Emma
- Moll Robin J.
- Molnar Zoltan
- Monahan Irene M.
- Mondani Matteo
- Mookerjee Siddharth
- Moore Catherine
- Moore Christopher
- Moore Jonathan
- Moore Nathan
- Moore Shona
- Morcrette Helen
- Morgan Mari
- Morgan Sian
- Mori Matilde
- Morriss Arthur
- Moses Samuel
- Mower Craig
- Muir Peter
- Mukaddas Afrida
- Munemo Florence
- Munn Robert
- Murcia Pablo R.
- Murray Abigail
- Murray Darren R.
- Murray Leanne J.
- Murray Sam M.
- Mutingwende Manasa
- Myers Richard
- Nastouli Eleni
- Nebbia Gaia
- Nelson Andrew
- Nelson Charlotte
- Nicholls Sam
- Nichols Jenna
- Nicodemi Roberto
- Nomikou Kyriaki
- O?Brien Sarah
- O?Grady Justin
- O?Toole Áine
- Odedra Mina
- Ohemeng-Kumi Natasha
- Oliver Karen
- Orton Richard
- Orton Richard J.
- Osman Husam
- Pacchiarini Nicole
- Padgett Debra
- Page Andrew J.
- Palmarini Massimo
- Park Emily J.
- Park Naomi R.
- Parker Matthew D.
- Parmar Surendra
- Partridge David G.
- Pascall David
- Pascall David J.
- Patel Amita
- Patel Arvind H.
- Patel Bindi
- Paterson Steve
- Payne Brendan A. I.
- Payne Rebecca
- Peacock Sharon J.
- Pearson Clare
- Pelosi Emanuela
- Percival Benita
- Perkins Jon
- Perry Malorie
- Pinckert Malte L.
- Pinto Rute Maria
- Platt Steven
- Podplomyk Olga
- Pohare Manoj
- Pond Marcus
- Pope Cassie F.
- Poplawski Radoslaw
- Powell Jessica
- Poyner Jennifer
- Prestwood Liam
- Price Anna
- Price James R.
- Prieto Jacqui A.
- Pritchard David T.
- Prosolek Sophie J.
- Pugh Georgia
- Pusok Monika
- Puxty Kathryn
- Pybus Oliver G.
- Pymont Hannah M.
- Quail Michael A.
- Quick Joshua
- Radulescu Clara
- Raghwani Jayna
- Ragonnet-Cronin Manon
- Rainbow Lucille
- Rajan Diana
- Rajatileka Shavanthi
- Ramadan Newara A.
- Rambaut Andrew
- Ramble John
- Randell Paul
- Randell Paul A.
- Ratcliffe Liz
- Raviprakash Veena
- Ray Surajit
- Raza Mohammad
- Redshaw Nicholas M.
- Rey Sara
- Reynolds Nicola
- Richter Alex
- Richter Alex
- Robertson David L.
- Robertson David L.
- Robinson Esther
- Robson Samuel C.
- Rogan Fiona
- Rooke Stefan
- Rowe Will
- Roy Sunando
- Rudder Steven
- Ruis Chris
- Rushton Steven
- Ryan Felicity
- Saeed Kordo
- Samaraweera Buddhini
- Sambles Christine M.
- Sanderson Roy
- Sanderson Theo
- Sang Fei
- Sass Thea
- Scher Emily
- Scott Carol
- Scott Garren
- Scott Sam
- Sehmi Jasveen
- Shaaban Sharif
- Shaaban Sharif
- Shah Divya
- Shaw Jessica
- Shelest Ekaterina
- Shepherd James G.
- Sheridan Liz A.
- Sheriff Nicola
- Shirley Lesley
- Sillitoe John
- Silva Vanessa
- Silviera Siona
- Simpson David A.
- Singh Aditi
- Singleton Dawn
- Skvortsov Timofey
- Sloan Tim J.
- Sluga Graciela
- Smith Colin P.
- Smith Darren L.
- Smith Ken
- Smith Kim S.
- Smith Louise
- Smith Nikki
- Smith Perminder
- Smollett Katherine
- Smollett Katherine L.
- Snell Luke B.
- Somassa Thomas
- Southgate Joel
- Spellman Karla
- Spencer Chapman Michael H.
- Spurgin Lewis G.
- Spyer Moira J.
- Stanley Rachael
- Stanley William
- Stanton Thomas D.
- Starinskij Igor
- Stockton Joanne
- Stonehouse Susanne
- Storey Nathaniel
- Studholme David J.
- Sudhanva Malur
- Swindells Emma
- Szemiel Agnieszka
- Taha Yusri
- Tan Ngee Keong
- Tang Julian W.
- Tang Miao
- Taylor Ben E. W.
- Taylor Joshua F.
- Taylor Sarah
- Temperton Ben
- Templeton Kate
- Templeton Kate E.
- Thomas Claire
- Thomson Emma C.
- Thomson Emma C.
- Thomson Laura
- Thornton Alicia
- Thurston Scott A. J.
- Todd John A.
- Tomb Rachael
- Tong Lily
- Tong Lily
- Tonkin-Hill Gerry
- Torok M. Estee
- Tovar-Corona Jaime M.
- Trebes Amy
- Trotter Alexander J.
- Tsatsani Ioulia
- Turnbull Robyn
- Turtle Lance
- Twohig Katherine A.
- Umpleby Helen
- Underwood Anthony P.
- Vamos Edith E.
- Vasylyeva Tetyana I.
- Vattipally Sreenu
- Vernet Gabrielle
- Vink Elen
- Vipond Barry B.
- Volz Erik M.
- Walsh Sarah
- Wang Dennis
- Warne Ben
- Warwick-Dugdale Joanna
- Wastnedge Elizabeth
- Watkins Joanne
- Watson Louisa K.
- Waugh Sheila
- Webster Hermione J.
- Weldon Danni
- Westwick Elaine
- Whalley Thomas
- Wheeler Helen
- Whitehead Mark
- Whiteley Max
- Whitwham Andrew
- Wierzbicki Claudia
- Wilkie Craig
- Willett Brian J.
- Willford Nicholas J.
- Williams Catryn
- Williams Charlotte A.
- Williams Cheryl
- Williams Chris
- Williams Lesley-Anne
- Williams Rachel J.
- Williams Rebecca
- Williams Thomas
- Williamson Kathleen A.
- Wilson-Davies Eleri
- Witele Eric
- Withell Karen T.
- Witney Adam A.
- Wolverson Paige
- Wong Nick
- Workman Trudy
- Wright Derek W.
- Wright Victoria
- Wyatt Tim
- Wyllie Sarah
- Xu-McCrae Li
- Yavus Mehmet
- Yaze Geraldine
- Yeats Corin A.
- Yebra Gonzalo
- Yebra Gonzalo
- Yew Wen C.
- Young Gregory R.
- Young Jamie
- Zarebski Alex E.
- Zhang Peijun
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 31/08/2022
- Field of study
Vaccines based on the spike protein of SARS-CoV-2 are a cornerstone of the public health response to COVID-19. The emergence of hypermutated, increasingly transmissible variants of concern (VOCs) threaten this strategy. Omicron (B.1.1.529), the fifth VOC to be described, harbours multiple amino acid mutations in spike, half of which lie within the receptor-binding domain. Here we demonstrate substantial evasion of neutralization by Omicron BA.1 and BA.2 variants in vitro using sera from individuals vaccinated with ChAdOx1, BNT162b2 and mRNA-1273. These data were mirrored by a substantial reduction in real-world vaccine effectiveness that was partially restored by booster vaccination. The Omicron variants BA.1 and BA.2 did not induce cell syncytia in vitro and favoured a TMPRSS2-independent endosomal entry pathway, these phenotypes mapping to distinct regions of the spike protein. Impaired cell fusion was determined by the receptor-binding domain, while endosomal entry mapped to the S2 domain. Such marked changes in antigenicity and replicative biology may underlie the rapid global spread and altered pathogenicity of the Omicron variant
Investigation of hospital discharge cases and SARS-CoV-2 introduction into Lothian care homes
- Author
- Aanensen David M.
- Abudahab Khalil
- Adams Alexander
- Adams Helen
- Afifi Safiah
- Aggarwal Dinesh
- Ahmad Shazaad SY.
- Aigrain Louise
- Alcolea-Medina Adela
- Alikhan Nabil-Fareed
- Allara Elias
- Amato Roberto
- Angyal Adrienn
- Annett Tara
- Aplin Stephen
- Ariani Cristina V.
- Asad Hibo
- Ash Amy
- Ashfield Paula
- Ashford Fiona
- Atkinson Laura
- Attwood Stephen W.
- Auckland Cressida
- Aydin Alp
- Baker David J.
- Baker Paul
- Balcazar Carlos E.
- Ball Jonathan
- Barrett Jeffrey C.
- Barrow Magdalena
- Barton Edward
- Bashton Matthew
- Bassett Andrew R.
- Batra Rahul
- Baxter Chris
- Bayzid Nadua
- Beaver Charlotte
- Beckett Angela H.
- Beckwith Shaun M.
- Bedford Luke
- Beer Robert
- Beggs Andrew
- Bellis Katherine L.
- Berry Louise
- Bertolusso Beatrice
- Best Angus
- Betteridge Emma
- Bibby David
- Bicknell Kelly
- Binns Debbie
- Birchley Alec
- Bird Paul W.
- Bishop Chloe
- Blacow Rachel
- Blakey Victoria
- Blane Beth
- Bolt Frances
- Bonfield James
- Bonner Stephen
- Bonsall David
- Boswell Tim
- Bosworth Andrew
- Bourgeois Yann
- Boyd Olivia
- Bradley Declan T.
- Breen Cassie
- Bresner Catherine
- Breuer Judith
- Bridgett Stephen
- Bronner Iraad F.
- Brooks Ellena
- Broos Alice
- Brown Julianne R.
- Bucca Giselda
- Buchan Sarah L.
- Buck David
- Bull Matthew
- Burns Phillipa J.
- Burton-Fanning Shirelle
- Byaruhanga Timothy
- Byott Matthew
- Campbell Sharon
- Carabelli Alessandro M.
- Cargill James S.
- Carlile Matthew
- Carvalho Sílvia F.
- Casey Anna
- Castigador Anibolina
- Catalan Jana
- Chalker Vicki
- Chaloner Nicola J.
- Chand Meera
- Chappell Joseph G.
- Charalampous Themoula
- Chatterton Wendy
- Chaudhry Yasmin
- Churcher Carol M.
- Clark Gemma
- Clarke Phillip
- Cogger Benjamin J.
- Cole Kevin
- Collins Jennifer
- Colquhoun Rachel
- Connor Thomas R.
- Cook Kate F.
- Coombes Jason
- Corden Sally
- Cormie Claire
- Cortes Nicholas
- Cotic Marius
- Cotton S.
- Cotton Seb
- Cottrell Simon
- Coupland Lindsay
- Cox Alison
- Cox MacGregor
- Craine Noel
- Crawford Liam
- Cross Aidan
- Crown Matthew R.
- Crudgington Dorian
- Cumley Nicola
- Curran Martin D.
- Curran Tanya
- Cutino-Moguel Teresa
- da Silva Filipe Ana
- Dabrer Gavin
- Darby Alistair C.
- Davidson Rose K.
- Davies Alisha
- Davies Robert M.
- Davis Thomas
- de Angelis Daniela
- De Lacy Elen
- de Oliveira Martins Leonardo
- de Silva Thushan I.
- Debebe Johnny
- Delgado Callico Laia
- Denton-Smith Rebecca
- Dervisevic Samir
- Dewar R.
- Dewar Rebecca
- Dey Jayasree
- Dias Joana
- Dobie Donald
- Dorman Matthew J.
- Downing Fatima
- Driscoll Megan
- du Plessis Louis
- Duckworth Nichola
- Durham Jillian
- Eastick Kirstine
- Easton Lisa J.
- Eccles Richard
- Edgeworth Jonathan
- Edwards Sue
- El Bouzidi Kate
- Eldirdiri Sahar
- Ellaby Nicholas
- Elliott Scott
- Eltringham Gary
- Ensell Leah
- Erkiert Michelle J.
- Essex Sarah
- Evans Cariad
- Evans Johnathan M.
- Everson William
- Fairley Derek J.
- Fallon Karlie
- Fanaie Arezou
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- Fearn Christopher
- Feltwell Theresa
- Ferguson Lynne
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- Fleming Vicki M.
- Forrest Sally
- Foster-Nyarko Ebenezer
- Foulkes Benjamin H.
- Foulser Luke
- Fragakis Mireille
- Frampton Dan
- Francois Sarah
- Fraser Christophe
- Freeman Timothy M.
- Fryer Helen
- Fuchs Marc
- Fuller William
- Gajee Kavitha
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- Gallagher Abbie
- Gallagher Eileen
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- Koshy Cherian
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- Manley Robin
- Mantzouratou Anna
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- Markov Anna
- Martincorena Inigo
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- Mayhew Megan
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- McKerr Caoimhe
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- McMurray Claire
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- Medd Nathan
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- Miskelly Julia
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- Moore Catherine
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- Morcrette Helen
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- Mower Craig
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- Starinskij Igor
- Stockton Joanne
- Stonehouse Susanne
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- Studholme David J.
- Sudhanva Malur
- Swindells Emma
- Taha Yusri
- Tan Ngee Keong
- Tang Julian W.
- Tang Miao
- Taylor Ben EW.
- Taylor Joshua F.
- Taylor Sarah
- Temperton Ben
- Templeton K.
- Templeton Kate E.
- Thomas Claire
- Thomas-McEwen Peter MD.
- Thomson Emma C.
- Thomson Laura
- Thornton Alicia
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- Todd John A.
- Tomb Rachael
- Tong Lily
- Tonkin-Hill Gerry
- Tovar-Corona Jaime M.
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- Turnbull Robyn
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- Vamos Edith E.
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- Webster Hermione J.
- Weldon Danni
- Westwick Elaine
- Whalley Thomas
- Wheeler Helen
- Whitehead Mark
- Whiteley Max
- Whitwham Andrew
- Wierzbicki Claudia
- Willford Nicholas J.
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- Williams Cheryl
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- Williams Rebecca
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- Witele Eric
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- Witney Adam A.
- Wolverson Paige
- Wong Nick
- Workma Trudy
- Wright Derek W.
- Wright Victoria
- Wyatt Tim
- Wyllie Sarah
- Xu-McCrae Li
- Yavus Mehmet
- Yaze Geraldine
- Yeats Corin A.
- Yebra Gonzalo
- Yew Wen C.
- Young Gregory R.
- Young Jamie
- Zarebski Alex E.
- Zhang Peijun
- Publication venue
- 'Elsevier BV'
- Publication date
- 09/03/2023
- Field of study
Background
The first epidemic wave of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in Scotland resulted in high case numbers and mortality in care homes. In Lothian, over one-third of care homes reported an outbreak, while there was limited testing of hospital patients discharged to care homes.
Aim
To investigate patients discharged from hospitals as a source of SARS-CoV-2 introduction into care homes during the first epidemic wave.
Methods
A clinical review was performed for all patients discharges from hospitals to care homes from 1st March 2020 to 31st May 2020. Episodes were ruled out based on coronavirus disease 2019 (COVID-19) test history, clinical assessment at discharge, whole-genome sequencing (WGS) data and an infectious period of 14 days. Clinical samples were processed for WGS, and consensus genomes generated were used for analysis using Cluster Investigation and Virus Epidemiological Tool software. Patient timelines were obtained using electronic hospital records.
Findings
In total, 787 patients discharged from hospitals to care homes were identified. Of these, 776 (99%) were ruled out for subsequent introduction of SARS-CoV-2 into care homes. However, for 10 episodes, the results were inconclusive as there was low genomic diversity in consensus genomes or no sequencing data were available. Only one discharge episode had a genomic, time and location link to positive cases during hospital admission, leading to 10 positive cases in their care home.
Conclusion
The majority of patients discharged from hospitals were ruled out for introduction of SARS-CoV-2 into care homes, highlighting the importance of screening all new admissions when faced with a novel emerging virus and no available vaccine
Measuring the health-related Sustainable Development Goals in 188 countries : a baseline analysis from the Global Burden of Disease Study 2015
- Author
- Abajobir Amanuel Alemu
- Abate Kalkidan Hassen
- Abbafati Cristiana
- Abbas Kaja M
- Abd El Razek Mohammed Magdy
- Abd-Allah Foad
- Abdulle Abdishakur M
- Abraham Biju
- Abu-Raddad Laith J
- Abu-Rmeileh Niveen ME
- Abubakar Ibrahim
- Abyu Gebre Yitayih
- Achoki Tom
- Adebiyi Akindele Olupelumi
- Adedeji Isaac Akinkunmi
- Afanvi Kossivi Agbelenko
- Afshin Ashkan
- Agarwal Arnav
- Agrawal Anurag
- Ahmadieh Hamid
- Ahmed Kedir Yimam
- Akanda Ali Shafqat
- Akinyemi Rufus Olusola
- Akinyemiju Tomi F
- Akseer Nadia
- Al-Aly Ziyad
- Al-Raddadi Rajaa
- Alam Khurshid
- Alam Uzma
- Alasfoor Deena
- AlBuhairan Fadia S
- Aldhahri Saleh Fahed
- Aldridge Robert William
- Alemu Zewdie Aderaw
- Ali Raghib
- Alkerwi Ala'a
- Alkhateeb Mohammad AB
- Alla Francois
- Allebeck Peter
- Allen Christine
- Allen Kate
- Alsharif Ubai
- Altirkawi Khalid A
- Alvis-Guzman Nelson
- Amare Azmeraw T
- Amberbir Alemayehu
- Amegah Adeladza Kofi
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- Awasthi Ashish
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- Barrientos-Gutierrez Tonatiuh
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- Chibalabala Mirriam
- Chisumpa Vesper Hichilombwe
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- Ciobanu Liliana G
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- Coates Matthew M
- Coggeshall Megan
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- Dandona Lalit
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- das Neves Jose
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- De la Cruz Monis Jonathan
- De Leo Diego
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- Kesavachandran Chandrasekharan Nair
- Khader Yousef Saleh
- Khan Abdur Rahman
- Khan Ejaz Ahmad
- Khan Gulfaraz
- Khang Young-Ho
- Khoja Tawfi K Ahmed Muthafer
- Khosravi Ardeshir
- Khubchandani Jagdish
- Kiadaliri Aliasghar Ahmad
- Kieling Christian
- Kim Cho-Il
- Kim Daniel
- Kim Sungroul
- Kim Yun Jin
- Kimokoti Ruth W
- Kinfu Yohannes
- Kissoon Niranjan
- Kivipelto Miia
- Knibbs Luke D
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- Kolte Dhaval
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- Yakob Bereket
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- Zaidi Zoubida
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- Zambrana-Torrelio Carlos
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- Publication venue
- Publication date
- 01/01/2016
- Field of study
Background In September, 2015, the UN General Assembly established the Sustainable Development Goals (SDGs). The SDGs specify 17 universal goals, 169 targets, and 230 indicators leading up to 2030. We provide an analysis of 33 health-related SDG indicators based on the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015). Methods We applied statistical methods to systematically compiled data to estimate the performance of 33 health-related SDG indicators for 188 countries from 1990 to 2015. We rescaled each indicator on a scale from 0 (worst observed value between 1990 and 2015) to 100 (best observed). Indices representing all 33 health-related SDG indicators (health-related SDG index), health-related SDG indicators included in the Millennium Development Goals (MDG index), and health-related indicators not included in the MDGs (non-MDG index) were computed as the geometric mean of the rescaled indicators by SDG target. We used spline regressions to examine the relations between the Socio-demographic Index (SDI, a summary measure based on average income per person, educational attainment, and total fertility rate) and each of the health-related SDG indicators and indices. Findings In 2015, the median health-related SDG index was 59.3 (95% uncertainty interval 56.8-61.8) and varied widely by country, ranging from 85.5 (84.2-86.5) in Iceland to 20.4 (15.4-24.9) in Central African Republic. SDI was a good predictor of the health-related SDG index (r(2) = 0.88) and the MDG index (r(2) = 0.2), whereas the non-MDG index had a weaker relation with SDI (r(2) = 0.79). Between 2000 and 2015, the health-related SDG index improved by a median of 7.9 (IQR 5.0-10.4), and gains on the MDG index (a median change of 10.0 [6.7-13.1]) exceeded that of the non-MDG index (a median change of 5.5 [2.1-8.9]). Since 2000, pronounced progress occurred for indicators such as met need with modern contraception, under-5 mortality, and neonatal mortality, as well as the indicator for universal health coverage tracer interventions. Moderate improvements were found for indicators such as HIV and tuberculosis incidence, minimal changes for hepatitis B incidence took place, and childhood overweight considerably worsened. Interpretation GBD provides an independent, comparable avenue for monitoring progress towards the health-related SDGs. Our analysis not only highlights the importance of income, education, and fertility as drivers of health improvement but also emphasises that investments in these areas alone will not be sufficient. Although considerable progress on the health-related MDG indicators has been made, these gains will need to be sustained and, in many cases, accelerated to achieve the ambitious SDG targets. The minimal improvement in or worsening of health-related indicators beyond the MDGs highlight the need for additional resources to effectively address the expanded scope of the health-related SDGs.Peer reviewe
Search for High-energy Neutrinos from Binary Neutron Star Merger GW170817 with ANTARES, IceCube, and the Pierre Auger Observatory
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- Publication venue
- IOP Publishing
- Publication date
- 21/08/2018
- Field of study