7 research outputs found
Health-related quality of life after angioplasty and stent placement in patients with iliac artery occlusive disease: results of a randomized controlled clinical trial.
BACKGROUND: To assess the quality of life in patients with iliac artery
occlusive disease, we compared primary stent placement versus primary
angioplasty followed by selective stent placement in a multicenter
randomized controlled trial. METHODS AND RESULTS: Quality-of-life
assessments were completed by 254 patients in a telephone interview.
Assessment measures consisted of the RAND 36-Item Health Survey 1.0, time
tradeoff, standard gamble, rating scale, health utilities index, and
EuroQol-5D. The interviews were performed before treatment and after 1, 3,
12, and 24 months. When the 2 treatments were compared, no significant
difference was observed (P>0.05). All measurements showed a significant
improvement in the quality of life after treatment (P<0.05). The RAND
36-Item Health Survey measures physical functioning, role limitations
caused by physical problems, and bodily pain and the EuroQol-5D were the
most sensitive to the impact of revascularization. CONCLUSIONS:
Health-related quality of life improves equally after primary stent
placement and primary angioplasty with selective stent placement in the
treatment of intermittent claudication caused by iliac artery occlusive
disease
Balloon dilation and stent implantation for treatment of femoropopliteal arterial disease: meta-analysis
PURPOSE: To perform a meta-analysis of long-term results of balloon
dilation and stent implantation in the treatment of femoropopliteal
arterial disease. MATERIALS AND METHODS: The English-language literature
was searched for studies published between 1993 and 2000. Inclusion
criteria for articles were presentation of long-term primary patency
rates, standard errors (explicitly reported or derivable), and baseline
characteristics of the study population. Two reviewers independently
extracted data, and discrepancies were resolved by consensus. Primary
patency rates were combined by using a technique that allows adjustment
for differences across study populations. Analyses were adjusted for
lesion type and clinical indication. RESULTS: Nineteen studies met the
inclusion criteria, representing 923 balloon dilations and 473 stent
implantations. Combined 3-year patency rates after balloon dilation were
61% (standard error, 2.2%) for stenoses and claudication, 48% (standard
error, 3.3%) for occlusions and claudication, 43% (standard error, 4.1%)
for stenoses and critical ischemia, and 30% (standard error, 3.7%) for
occlusions and critical ischemia. The 3-year patency rates after stent
implantation were 63%-66% (standard error, 4.1%) and were independent of
clinical indication and lesion type. Funnel plots demonstrated an
asymmetric distribution of the data points associated with stent studies.
CONCLUSION: Balloon dilation and stent implantation for claudication and
stenosis yield similar long-term patency rates. For more severe
femoropopliteal disease, the results of stent implantation seem more
favorable. Publication bias could not be ruled out
Stent placement for renal arterial stenosis: where do we stand? A meta-analysis
PURPOSE: To perform a meta-analysis of renal arterial stent placement in
comparison with renal percutaneous transluminal angioplasty (PTA) in
patients with renal arterial stenosis. MATERIALS AND METHODS: Studies
dealing with renal arterial stent placement (14 articles; 678 patients)
and renal PTA (10 articles; 644 patients) published up to August 1998 were
selected. A random-effects model was used to pool the data. RESULTS: Renal
arterial stent placement proved highly successful, with an initial
adequate performance in 98% and major complications in 11%. The overall
cure rate for hypertension was 20%, whereas hypertension was improved in
49%. Renal function improved in 30% and stabilized in 38% of patients. The
restenosis rate at follow-up of 6-29 months was 17%. Stent placement had a
higher technical success rate and a lower restenosis rate than did renal
PTA (98% vs 77% and 17% vs 26%, respectively; P <.001). The complication
rate was not different between the two treatments. The cure rate for
hypertension was higher and the improvement rate for renal function was
lower after stent placement than after renal PTA (20% vs 10% and 30% vs
38%, respectively; P <.001). CONCLUSION: Renal arterial stent placement is
technically superior and clinically comparable to renal PTA alone
Large expert-curated database for benchmarking document similarity detection in biomedical literature search
Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical research.Peer reviewe
Health-Related Quality of Life After Angioplasty and Stent Placement in Patients With Iliac Artery Occlusive Disease
BACKGROUND: To assess the quality of life in patients with iliac artery
\n occlusive disease, we compared primary stent placement versus primary
\n angioplasty followed by selective stent placement in a multicenter
\n randomized controlled trial. METHODS AND RESULTS: Quality-of-life
\n assessments were completed by 254 patients in a telephone interview.
\n Assessment measures consisted of the RAND 36-Item Health Survey 1.0, time
\n tradeoff, standard gamble, rating scale, health utilities index, and
\n EuroQol-5D. The interviews were performed before treatment and after 1, 3,
\n 12, and 24 months. When the 2 treatments were compared, no significant
\n difference was observed (P>0.05). All measurements showed a significant
\n improvement in the quality of life after treatment (P<0.05). The RAND
\n 36-Item Health Survey measures physical functioning, role limitations
\n caused by physical problems, and bodily pain and the EuroQol-5D were the
\n most sensitive to the impact of revascularization. CONCLUSIONS:
\n Health-related quality of life improves equally after primary stent
\n placement and primary angioplasty with selective stent placement in the
\n treatment of intermittent claudication caused by iliac artery occlusive
\n disease
Systematic review and meta-analysis of sex differences in outcome after intervention for abdominal aortic aneurysm
Background: The aim of this study was to assess possible differences in mortality between men and women with an abdominal aortic aneurysm (AAA) treated either by elective repair or following aneurysm rupture. Metlioclss A systematic literature search was performed using the MEDLINE, Cochrane and Embase databases. Data were analysed by means of bivariate random-effects meta-analysis. Data were pooled and odds ratios (ORs) calculated for women compared with men. Resulte: Sixty-one studies (516118 patients) met the predetermined inclusion criteria. Twenty-six reported on elective open AAA repair, 21 on elective endovascular repair, 25 on open repair for ruptured AAA and one study on endovascular repair for ruptured AAA Mortality rates for women compared with men were 7-6 versus 5-1 per cent (OR 1-28, 95 per cent confidence interval (c.i.) 1.09 to 1.49) for elective open repair, 2-9 versus 1.5 per cent (OR 2.41, 95 per cent c.i. 1.14 to 5.15) for elective endovascular repair, and 61.8 versus 42.2 percent (OR 1.16, 95 perent c.i. 0.97 to 1.37) in the group that had open repair for rupture. The group that had endovascular repair for ruptured AAA was too small for meaningful analysis. Concluslon: Women with an AAA had a higher mortality rate following elective open and endovascular repair. Copyrigh