2,395 research outputs found

    Incidence and genetic diversity of cucurbit viruses in Spain

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    [EN] Several viral diseases affect cucurbits, with different economic effects depending on the region and the year. However, there are not recent studies on the incidence of specific viruses. During the 2018 summer season, surveys were carried out in open field melon (Cucumis melo), squash (Cucurbita spp.) and watermelon (Citrullus lanatus) crops in most of the main producer areas under commercial (AGL2017-85563-C2 1R and 2R) and organic farming (PROMETEO/2017/078). Samples from plants with virus-like symptoms were analyzed by RT-PCR/PCR with specific primers, hybridization and/or ELISA, to detect Cucumber mosaic virus (CMV), Zucchini yellow mosaic virus (ZYMV), Watermelon mosaic virus (WMV), Moroccan watermelon mosaic virus (MWMV), Cucurbit yellow stunting disorder virus (CYSDV), Cucurbit chlorotic yellows virus (CCYV), Cucumber green mottle mosaic virus (CGMMV) and Tomato leaf curl New Delhi virus (ToLCNDV). Samples from fields in Murcia (south-eastern Spain), Castilla-La Mancha (central Spain) and Comunidad Valenciana (eastern Spain) were analyzed. At least one of these viruses was detected in approximately 80% of the samples. WMV was the most frequently detected in samples of the three crops. ZYMV, CMV, CYSDV and ToLCNDV were present with lower incidence, mainly identified in mixed infections with WMV.This study was partially supported by the Spanish Ministerio de Ciencia, Innovación y Universidades grants AGL2017-85563-C2 (1-R and 2-R) and RTA2017-00061-C03-03 (INIA) cofounded with FEDER funds, and by the PROMETEO project 2017/078 (to promote excellence groups) by the Conselleria d'Educació , Investigació , Cultura i Esports (Generalitat Valenciana). C. Sáez is a recipient of a predoctoral fellowship (ACIF/2016/188) from Generalitat Valenciana, cofunded by the Operational Program of the European Social Fund (FSECV 2014-2020).Pérez De Castro, AM.; Martínez De Alba, AE.; Sáez-Sánchez, C.; Flores-León, A.; Sifres Cuerda, AG.; Gómez-Guillamón, ML.; López Del Rincón, C.... (2020). Incidence and genetic diversity of cucurbit viruses in Spain. Acta Horticulturae. 1294:203-210. https://doi.org/10.17660/ActaHortic.2020.1294.25S203210129

    Precise measurement of the W-boson mass with the CDF II detector

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    We have measured the W-boson mass MW using data corresponding to 2.2/fb of integrated luminosity collected in proton-antiproton collisions at 1.96 TeV with the CDF II detector at the Fermilab Tevatron collider. Samples consisting of 470126 W->enu candidates and 624708 W->munu candidates yield the measurement MW = 80387 +- 12 (stat) +- 15 (syst) = 80387 +- 19 MeV. This is the most precise measurement of the W-boson mass to date and significantly exceeds the precision of all previous measurements combined

    Search for new physics with same-sign isolated dilepton events with jets and missing transverse energy

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    A search for new physics is performed in events with two same-sign isolated leptons, hadronic jets, and missing transverse energy in the final state. The analysis is based on a data sample corresponding to an integrated luminosity of 4.98 inverse femtobarns produced in pp collisions at a center-of-mass energy of 7 TeV collected by the CMS experiment at the LHC. This constitutes a factor of 140 increase in integrated luminosity over previously published results. The observed yields agree with the standard model predictions and thus no evidence for new physics is found. The observations are used to set upper limits on possible new physics contributions and to constrain supersymmetric models. To facilitate the interpretation of the data in a broader range of new physics scenarios, information on the event selection, detector response, and efficiencies is provided.Comment: Published in Physical Review Letter

    Search for anomalous t t-bar production in the highly-boosted all-hadronic final state

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    A search is presented for a massive particle, generically referred to as a Z', decaying into a t t-bar pair. The search focuses on Z' resonances that are sufficiently massive to produce highly Lorentz-boosted top quarks, which yield collimated decay products that are partially or fully merged into single jets. The analysis uses new methods to analyze jet substructure, providing suppression of the non-top multijet backgrounds. The analysis is based on a data sample of proton-proton collisions at a center-of-mass energy of 7 TeV, corresponding to an integrated luminosity of 5 inverse femtobarns. Upper limits in the range of 1 pb are set on the product of the production cross section and branching fraction for a topcolor Z' modeled for several widths, as well as for a Randall--Sundrum Kaluza--Klein gluon. In addition, the results constrain any enhancement in t t-bar production beyond expectations of the standard model for t t-bar invariant masses larger than 1 TeV.Comment: Submitted to the Journal of High Energy Physics; this version includes a minor typo correction that will be submitted as an erratu

    Performance of the CMS Cathode Strip Chambers with Cosmic Rays

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    The Cathode Strip Chambers (CSCs) constitute the primary muon tracking device in the CMS endcaps. Their performance has been evaluated using data taken during a cosmic ray run in fall 2008. Measured noise levels are low, with the number of noisy channels well below 1%. Coordinate resolution was measured for all types of chambers, and fall in the range 47 microns to 243 microns. The efficiencies for local charged track triggers, for hit and for segments reconstruction were measured, and are above 99%. The timing resolution per layer is approximately 5 ns

    Novel Insights into Pituitary Tumorigenesis: Genetic and Epigenetic Mechanisms.

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    Substantial advances have been made recently in the pathobiology of pituitary tumors. Similar to many other endocrine tumors, over the last few years we have recognized the role of germline and somatic mutations in a number of syndromic or nonsyndromic conditions with pituitary tumor predisposition. These include the identification of novel germline variants in patients with familial or simplex pituitary tumors and establishment of novel somatic variants identified through next generation sequencing. Advanced techniques have allowed the exploration of epigenetic mechanisms mediated through DNA methylation, histone modifications and noncoding RNAs, such as microRNA, long noncoding RNAs and circular RNAs. These mechanisms can influence tumor formation, growth, and invasion. While genetic and epigenetic mechanisms often disrupt similar pathways, such as cell cycle regulation, in pituitary tumors there is little overlap between genes altered by germline, somatic, and epigenetic mechanisms. The interplay between these complex mechanisms driving tumorigenesis are best studied in the emerging multiomics studies. Here, we summarize insights from the recent developments in the regulation of pituitary tumorigenesis
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