Utilizing Social Networks in Language Classes – Perception, Production, and Interaction

The ubiquitous presence of social network sites (SNSs) offers both promises and problems for language teaching and learning today. Between 2009 and 2016 the authors incorporated Facebook into their Chinese curricula in three higher education institutions and subsequently analyzed its affordances and implications. Based on student surveys and language data collected from these pedagogical experiments, this action research paper explores three aspects of the findings: students’ perception, language production, and language interaction. The discussion focuses on not only the utilization of SNSs as educational tools to engage Chinese learners in innovative and collaborative ways but also helpful suggestions for teachers to enhance instructional outcomes through SNSs. Specific attention is given to create a pedagogically effective, privacy-ensured, and userfriendly social network project with Facebook, which is applicable to other SNSs and similar digital platforms

"Case files from the University of Florida: When an Earache is more than an Earache": A case report

Brain abscess is not a common diagnosis as there are only approximately 2000 cases reported each year in the United States. There are three main routes of access to the brain including contiguous infection from the oropharynx, direct implantation and hematogenously. We present a case of brain abscess in a child who had multiple visits for ear pain to various physicians including pediatricians and to emergency departments. Additionally, the microbiology of brain abscesses is briefly discussed, as is treatment

Biodistribution, clearance, and long‐term fate of clinically relevant nanomaterials

Realization of the immense potential of nanomaterials for biomedical applications will require a thorough understanding of how they interact with cells, tissues, and organs. There is evidence that, depending on their physicochemical properties and subsequent interactions, nanomaterials are indeed taken up by cells. However, the subsequent release and/or intracellular degradation of the materials, transfer to other cells, and/or translocation across tissue barriers are still poorly understood. The involvement of these cellular clearance mechanisms strongly influences the long-term fate of used nanomaterials, especially if one also considers repeated exposure. Several nanomaterials, such as liposomes and iron oxide, gold, or silica nanoparticles, are already approved by the American Food and Drug Administration for clinical trials; however, there is still a huge gap of knowledge concerning their fate in the body. Herein, clinically relevant nanomaterials, their possible modes of exposure, as well as the biological barriers they must overcome to be effective are reviewed. Furthermore, the biodistribution and kinetics of nanomaterials and their modes of clearance are discussed, knowledge of the long-term fates of a selection of nanomaterials is summarized, and the critical points that must be considered for future research are addressed

Attenuated Glial Reactivity on Topographically Functionalized Poly(3,4-Ethylenedioxythiophene):P-Toluene Sulfonate (PEDOT:PTS) Neuroelectrodes Fabricated by Microimprint Lithography

Following implantation, neuroelectrode functionality is susceptible to deterioration via reactive host cell response and glial scar-induced encapsulation. Within the neuroengineering community, there is a consensus that the induction of selective adhesion and regulated cellular interaction at the tissue–electrode interface can significantly enhance device interfacing and functionality in vivo. In particular, topographical modification holds promise for the development of functionalized neural interfaces to mediate initial cell adhesion and the subsequent evolution of gliosis, minimizing the onset of a proinflammatory glial phenotype, to provide long-term stability. Herein, a low-temperature microimprint-lithography technique for the development of micro-topographically functionalized neuroelectrode interfaces in electrodeposited poly(3,4-ethylenedioxythiophene):p-toluene sulfonate (PEDOT:PTS) is described and assessed in vitro. Platinum (Pt) microelectrodes are subjected to electrodeposition of a PEDOT:PTS microcoating, which is subsequently topographically functionalized with an ordered array of micropits, inducing a significant reduction in electrode electrical impedance and an increase in charge storage capacity. Furthermore, topographically functionalized electrodes reduce the adhesion of reactive astrocytes in vitro, evident from morphological changes in cell area, focal adhesion formation, and the synthesis of proinflammatory cytokines and chemokine factors. This study contributes to the understanding of gliosis in complex primary mixed cell cultures, and describes the role of micro-topographically modified neural interfaces in the development of stable microelectrode interfaces

Follicle-Stimulating Hormone Receptor: Advances and Remaining Challenges

International audienc

Climate Change Impacts on Net Ecosystem Productivity in a Subtropical Shrubland of Northwestern México

The sensitivity of semiarid ecosystems to climate change is not well understood due to competing effects of soil and plantâ mediated carbon fluxes. Limited observations of net ecosystem productivity (NEP) under rising air temperature and CO2 and altered precipitation regimes also hinder climate change assessments. A promising avenue for addressing this challenge is through the application of numerical models. In this work, we combine a mechanistic ecohydrological model and a soil carbon model to simulate soil and plant processes in a subtropical shrubland of northwest México. Due to the influence of the North American monsoon, the site exhibits net carbon losses early in the summer and net carbon gains during the photosynthetically active season. After building confidence in the simulations through comparisons with eddy covariance flux data, we conduct a series of climate change experiments for nearâ future (2030â 2045) scenarios that test the impact of meteorological changes and CO2 fertilization relative to historical conditions (1990â 2005). Results indicate that reductions in NEP arising from warmer conditions are effectively offset by gains in NEP due to the impact of higher CO2 on water use efficiency. For cases with higher summer rainfall and CO2 fertilization, climate change impacts lead to an increase of ~25% in NEP relative to historical conditions (mean of 66 g C mâ 2). Net primary production and soil respiration derived from decomposition are shown to be important processes that interact to control NEP and, given the role of semiarid ecosystems in the global carbon budget, deserve attention in future simulation efforts of ecosystem fluxes.Key PointsModel simulation accurately captured the seasonality of vegetation activityNet ecosystem productivity decreased under reduced summer rainfall and increased temperature scenariosElevated CO2 scenarios offset the negative impacts of meteorological conditionsPeer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/142969/1/jgrg20992_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/142969/2/jgrg20992.pd