Easing the Learning Curve: The Creation of Digital Learning Objects for Use in Special Collections Student Training

Low-staffed and often under-funded, academic libraries have traditionally relied upon student labor to maintain library services and to complete a seemingly unending workload. The use of students within the archival or special collections setting is no different. Special Collections departments often use students to complete tasks that could be reserved to the realm of professional staff. These include processing collections, preservation and conservation work, digitizing, and providing reference assistance

Privacy and Confidentiality Issues in Historical Health Sciences Collections

Historical health sciences collections are rare and unique materials containing large amounts of information subject to confidentiality and privacy laws and concerns. Formerly, the custodians of these collections handled these issues in relative obscurity, but technological changes and changing laws and norms around health care privacy have made these issues more acute and public. The intent of this Article is to describe the nature of these collections and the qualifications of the people who administer them, and to analyze some of the privacy and confidentiality issues that arise in the course of that work. The aim is to acquaint privacy officers, in-house legal counsel, and other members of the legal profession with the privacy and confidentiality challenges that these collections present, with the needs of researchers who use these collections, and with the reasons why historical health sciences collections are important.Publisher allows immediate open acces

The Effects of a School-Based Program on the Reported Self-Advocacy Knowledge of Students With Learning Disabilities

A school-based study examined self-reported self-advocacy knowledge of middle school students with learning disabilities (LD). Children with LD are vulnerable to experiencing psychosocial and academic problems. Self-advocacy is a protective factor as students with LD enter middle and high school, comprising knowledge of one’s learning strengths and LD; awareness of one’s rights and responsibilities; awareness of accommodations needed; and ability to communicate one’s learning needs and required accommodations. The students reported increasing their ability to advocate for themselves. Results underscore the importance of adults such as teachers and parents discussing LD and associated issues with children and youth.Une étude en milieu scolaire a examiné les perceptions qu’avaient des élèves à l’école intermédiaire ayant des troubles d’apprentissage par rapport à leur autonomie sociale. Ces élèves sont à risque de souffrir de problèmes psychosociaux et académiques. L’autonomie sociale constitue un facteur de protection quand les élèves ayant des troubles d’apprentissage commencent l’école intermédiaire ou secondaire. Elle implique la connaissance de ses forces académiques et de ses troubles d’apprentissage; la conscience de ses droits et ses responsabilités; la conscience des accommodations nécessaires; et la capacité de faire connaître ses besoins en matière d’apprentissage et d’accommodations. Les élèves ont indiqué qu’ils se sentaient mieux en mesure de se défendre. Les résultats soulignent l’importance pour les adultes comme les enseignants et les parents de discuter de troubles d’apprentissage et d’enjeux qui s’y rattachent avec les enfants et les jeunes

Teachers’ Understanding of Bullying

Using semi‐structured interviews, we examined teachers’ understanding of bullying of children in their classes. Although teachers’ definitions of bullying included both direct and indirect behaviours, several factors influenced how they characterized and responded to incidents. These factors included whether the teachers viewed an incident as serious or considered a victimized child responsible, whether a child matched their assumptions about victim characteristics and behaviours, and whether they described feeling empathy for a child. The nature of the school environment and organization such as availability of systemic support in addressing bullying incidents were further factors that influenced teachers’ awareness and responses. Key words: peer victimization, qualitative study on bullying, understanding bullying, response to bullying À l’aide d’entrevues semi‐structurées, les auteures ont étudié comment les enseignants perçoivent l’intimidation dans leurs classes. Bien que leurs définitions de l’intimidation comprennent à la fois les comportements directs et indirects, plusieurs facteurs influencent leur façon de caractériser les incidents et d’y réagir, notamment s’ils considèrent que l’incident est sérieux ou que la victime est responsable, si la victime correspond à leurs théories implicites sur les caractéristiques et les comportements d’une victime et s’ils ressentent de l’empathie pour la victime. Le climat de l’école et les structures offertes tel un soutien systémique pour faire face aux incidents d’intimidation faisaient également partie des facteurs ayant une incidence sur la sensibilisation et les réactions des enseignants. Mots clés: victimisation par des pairs, étude qualitative sur l’intimidation, comprendre l’intimidation, réagir à l’intimidation.

‘Justice system data’: a comparative study

A report examining how Canada, Australia and Ireland manage the data and information that is generated by their justice system

Muscle-related traits in cattle: The role of the myostatin gene in the South Devon breed

In this paper, we examined the effects of an 11-bp mutation within the GDF-8 gene, originally identified in Belgian Blue cattle, in the South Devon breed. The mutation was found at moderate frequency (0.37) in the South Devon population. We quantified the effects of this mutation on growth, body composition and calving traits in South Devon cattle. We found that the mutation significantly increased muscle score and calving difficulty and decreased fat depth. The mutation did not significantly affect weight at 200 and 400 days or muscle depth. Its effect on muscle score and fat depth was additive while its effect on calving difficulty was recessive. The mutation accounted for a significant proportion of the phenotypic variance in muscle score and calving difficulty. There was an economic benefit of the mutation for this data set, however, calculations were sensitive to changes in the parameter values. Additional data would be required to refine these calculations

Spatial Distribution of Stem Cell-Like Keratinocytes in Dissected Compound Hair Follicles of the Dog

Hair cycle disturbances are common in dogs and comparable to some alopecic disorders in humans. A normal hair cycle is maintained by follicular stem cells which are predominately found in an area known as the bulge. Due to similar morphological characteristics of the bulge area in humans and dogs, the shared particularity of compound hair follicles as well as similarities in follicular biomarker expression, the dog is a promising model to study human hair cycle and stem cell disorders. To gain insight into the spatial distribution of follicular keratinocytes with stem cell potential in canine compound follicles, we microdissected hair follicles in anagen and telogen from skin samples of freshly euthanized dogs. The keratinocytes isolated from different locations were investigated for their colony forming efficiency, growth and differentiation potential as well as clonal growth. Our results indicate that i) compound and single hair follicles exhibit a comparable spatial distribution pattern with respect to cells with high growth potential and stem cell-like characteristics, ii) the lower isthmus (comprising the bulge) harbors most cells with high growth potential in both, the anagen and the telogen hair cycle stage, iii) unlike in other species, colonies with highest growth potential are rather small with an irregular perimeter and iv) the keratinocytes derived from the bulbar region exhibit characteristics of actively dividing transit amplifying cells. Our results now provide the basis to conduct comparative studies of normal dogs and those with hair cycle disorders with the possibility to extend relevant findings to human patients

Transformations of the Sacred in East Timor

For Catholic missionaries in the early twentieth century, the only way to achieve true conversion of Timorese ancestral ritualists was the deliberate destruction of sacred lulik houses. Although Timorese allegedly participated enthusiastically in this destruction, lulik (a term commonly translated as sacred, proscribed, holy, or taboo) remains a key part of ritual practice today. This article offers a dynamic historical analysis of what may be described as a particular form of Southeast Asian animism, examining how people’s relationships with sacred powers have changed in interaction with Catholic missionaries. It links the inherent ambivalence of endogenous occult powers to religious and historical transformations, teasing out the unintended consequences of the missionaries’ attempts to eradicate and demonize lulik. Comparing historical and ethnographic data from the center of East Timor, it argues that contrary to the missionaries’ intentions, the cycles of destruction, withdrawal, and return, that characterized mission history ended up strengthening lulik. Inspired by anthropological studies of “taboo” and “otherness,” especially the work of Mary Douglas and Valerio Valeri, this article makes visible the transformation of the sacred in relation to outside agents: when relations with foreign powers were productive, the positive sides of lulik as a source of wealth and authority were brought out; yet when outsiders posed a threat, the dangerous and threatening aspects of lulik were accentuated. This analysis allows us to highlight the relational dimensions of sacred powers and their relation to ongoing social transformations

The Effect of Pulmonary Artery Catheter Use on Costs and Long-Term Outcomes of Acute Lung Injury

Background: The pulmonary artery catheter (PAC) remains widely used in acute lung injury (ALI) despite known complications and little evidence of improved short-term mortality. Concurrent with NHLBI ARDS Clinical Trials Network Fluid and Catheters Treatment Trial (FACTT), we conducted a prospectively-defined comparison of healthcare costs and long-term outcomes for care with a PAC vs. central venous catheter (CVC). We explored if use of the PAC in ALI is justified by a beneficial cost-effectiveness profile. Methods: We obtained detailed bills for the initial hospitalization. We interviewed survivors using the Health Utilities Index Mark 2 questionnaire at 2, 6, 9 and 12 m to determine quality of life (QOL) and post-discharge resource use. Outcomes beyond 12 m were estimated from federal databases. Incremental costs and outcomes were generated using MonteCarlo simulation. Results: Of 1001 subjects enrolled in FACTT, 774 (86%) were eligible for long-term follow-up and 655 (85%) consented. Hospital costs were similar for the PAC and CVC groups ($96.8k vs.$89.2k, p = 0.38). Post-discharge to 12 m costs were higher for PAC subjects ($61.1k vs. 45.4k, p = 0.03). One-year mortality and QOL among survivors were similar in PAC and CVC groups (mortality: 35.6$14.4k and mean loss of 0.3 quality-adjusted life years (QALYs)) and a 94.2% probability of being higher than the $100k/QALY willingness-to-pay threshold. Conclusion: PAC use increased costs with no patient benefit and thus appears unjustified for routine use in ALI. Trial Registration: www.clinicaltrials.gov NCT00234767. © 2011 Clermont et al

Large expert-curated database for benchmarking document similarity detection in biomedical literature search

Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical research.Peer reviewe