Syntheses and spectral studies of novel ciprofloxacin derivatives

Reaction of 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid (ciprofloxacin) with thiazole/benzothiazole diazonium chloride afforded piperazine substituted ciprofloxacin derivative. The acid part of these derivatives was further condensed with various β-diketones to get 1-cyclopropyl-6-fluoro-4-oxo-7-(4-(thiazol-2-yldiazenyl)piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid derivatives (5a-e) and 7-(4-(benzo[d]thiazol-2-yldiazenyl)piperazin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid derivatives (5f-j). Structures of these compounds were established on the basis of spectral studies. KEY WORDS: Ciprofloxacin, Thiazole, Benzothiazole, β-Diketone  Bull. Chem. Soc. Ethiop. 2008, 22(3), 459-464. 

Profiles of emission lines generated by rings orbiting braneworld Kerr black holes

In the framework of the braneworld models, rotating black holes can be described by the Kerr metric with a tidal charge representing the influence of the non-local gravitational (tidal) effects of the bulk space Weyl tensor onto the black hole spacetime. We study the influence of the tidal charge onto profiled spectral lines generated by radiating tori orbiting in vicinity of a rotating black hole. We show that with lowering the negative tidal charge of the black hole, the profiled line becomes to be flatter and wider keeping their standard character with flux stronger at the blue edge of the profiled line. The extension of the line grows with radius falling and inclination angle growing. With growing inclination angle a small hump appears in the profiled lines due to the strong lensing effect of photons coming from regions behind the black hole. For positive tidal charge ($b>0$) and high inclination angles two small humps appear in the profiled lines close to the red and blue edge of the lines due to the strong lensing effect. We can conclude that for all values of $b$, the strongest effect on the profiled lines shape (extension) is caused by the changes of the inclination angle.Comment: Accepted by General Relativity and Gravitatio

Revisiting the transit timing and atmosphere characterization of the Neptune-mass planet HAT-P-26 b

We present a transit-timing variation (TTV) and planetary atmosphere analysis of the Neptune-mass planet HAT-P-26 b. We present a new set of 13 transit light curves from optical ground-based observations and combine them with light curves from the Wide Field Camera 3 on the Hubble Space Telescope, the Transiting Exoplanet Survey Satellite, and previously published ground-based data. We refine the planetary parameters of HAT-P-26 b and undertake a TTV analysis using 33 transits obtained over seven years. The TTV analysis shows an amplitude signal of 1.98 ± 0.05 minutes, which could result from the presence of an additional ∼0.02 MJup planet at a 1:2 mean-motion resonance orbit. Using a combination of transit depths spanning optical to near-infrared wavelengths, we find that the atmosphere of HAT-P-26 b contains ${2.4}_{-1.6}^{+2.9}$% H2O with a derived temperature of ${590}_{-50}^{+60}$ K

TransitFit: combined multi-instrument exoplanet transit fitting for JWST, HST, and ground-based transmission spectroscopy studies

We present TRANSITFIT1, a package designed to fit exoplanetary transit light curves. TRANSITFIT offers multi-epoch, multi-wavelength fitting of multi-telescope transit data. TRANSITFIT allows per-telescope detrending to be performed simultaneously with transit parameter fitting, including custom detrending. Host limb darkening can be fitted using prior conditioning from stellar atmosphere models. We demonstrate TRANSITFIT in a number of contexts. We model multi-telescope broad-band optical data from the ground-based SPEARNET survey of the low-density hot-Neptune WASP-127b and compare results to a previously published higher spectral resolution GTC/OSIRIS transmission spectrum. Using TRANSITFIT, we fit 26 transit epochs by TESS to recover improved ephemeris of the hot-Jupiter WASP-91b and a transit depth determined to a precision of 111 ppm. We use TRANSITFIT to conduct an investigation into the contested presence of TTV signatures in WASP-126b using 180 transits observed by TESS, concluding that there is no statistically significant evidence for such signatures from observations spanning 27 TESS sectors. We fit HST observations of WASP-43 b, demonstrating how TRANSITFIT can use custom detrending algorithms to remove complex baseline systematics. Lastly, we present a transmission spectrum of the atmosphere of WASP-96b constructed from simultaneous fitting of JWST NIRISS Early Release Observations and archive HST WFC3 transit data. The transmission spectrum shows generally good correspondence between spectral features present in both data sets, despite very different detrending requirements

Search for strong gravity in multijet final states produced in pp collisions at √s=13 TeV using the ATLAS detector at the LHC

A search is conducted for new physics in multijet final states using 3.6 inverse femtobarns of data from proton-proton collisions at √s = 13TeV taken at the CERN Large Hadron Collider with the ATLAS detector. Events are selected containing at least three jets with scalar sum of jet transverse momenta (HT) greater than 1TeV. No excess is seen at large HT and limits are presented on new physics: models which produce final states containing at least three jets and having cross sections larger than 1.6 fb with HT > 5.8 TeV are excluded. Limits are also given in terms of new physics models of strong gravity that hypothesize additional space-time dimensions

Search for leptophobic Z ' bosons decaying into four-lepton final states in proton-proton collisions at root s=8 TeV

Peer reviewe

Search for black holes and other new phenomena in high-multiplicity final states in proton-proton collisions at root s=13 TeV

Peer reviewe

Measurements of differential production cross sections for a Z boson in association with jets in pp collisions at root s=8 TeV

Peer reviewe

Search for high-mass diphoton resonances in proton-proton collisions at 13 TeV and combination with 8 TeV search

Peer reviewe