Análisis de los contenidos curriculares de la formación de los docentes de Educación Física en Iberoamérica: los casos de República Dominicana, Puerto Rico y México

El presente estudio forma parte del proyecto de investigación “La elaboración de una propuesta de diseño del currículo para la formación de docentes de Educación Física en Iberoamérica”, proyecto dedicado a examinar y describir el componente del campo curricular de la formación específica en Institutos y Universidades de Educación Física de los países Iberoamericanos. Utilizando como metodología el análisis de contenido, y la referencia conceptual originada en la Praxiología motriz pretende analizar el porcentaje de contenidos que pueden ser considerados específicos en el sentido disciplinar, utilizando las categorías praxiomotrices, nominadas como Deporte, Juego motor, Expresión corporal, Introyección motriz, Adaptación ambiental.Departamento de Educación Físic

Evolución tórpida de enfermedad de Fabry en tratamiento con agalsidasa alfa: Presentación de un caso

Fabry disease is characterized by the absence of activity of the lysosomal enzyme α-galactosidase A, which causes glycolipids, which should be broken down, to accumulate in the lysosomes of the cells of various tissues in the body, causing the signs and characteristic symptoms of this pathology. The severity of the disease depends on the level of mutation of the α-galactosidase A gene, which goes hand in hand with the age at presentation of symptoms, if we have a large mutation, we will have an earlier onset of it. For women, it is more frequent that the course of this condition is asymptomatic, most of them function as transmitters of Fabry disease, on the contrary, it has a predilection towards men. The most frequent clinical manifestations are angiokeratomas, acroparesthesias, anhidrosis, whorled cornea and in cases of death, they are related to kidney failure due to the progressive kidney failure it causes, heart failure or cerebrovascular disease. There is no cure for this deficiency, but we can stop its progress. For this purpose, two treatments have been developed: the first is enzyme replacement with agalsidase beta and the second with agalsidase alfa, whose effectiveness we will evaluate in a patient with Fabry disease compared to studies with enzyme replacement therapy with agalsidase beta.Fabry disease is characterized by the absence of activity of the lysosomal enzyme α-galactosidase A, which causes glycolipids, which should be broken down, to accumulate in the lysosomes of the cells of various tissues in the body, causing the signs and characteristic symptoms of this pathology. The severity of the disease depends on the level of mutation of the α-galactosidase A gene, which goes hand in hand with the age at presentation of symptoms, if we have a large mutation, we will have an earlier onset of it. For women, it is more frequent that the course of this condition is asymptomatic, most of them function as transmitters of Fabry disease, on the contrary, it has a predilection towards men. The most frequent clinical manifestations are angiokeratomas, acroparesthesias, anhidrosis, whorled cornea and in cases of death, they are related to kidney failure due to the progressive kidney failure it causes, heart failure or cerebrovascular disease. There is no cure for this deficiency, but we can stop its progress. For this purpose, two treatments have been developed: the first is enzyme replacement with agalsidase beta and the second with agalsidase alfa, whose effectiveness we will evaluate in a patient with Fabry disease compared to studies with enzyme replacement therapy with agalsidase beta

Evolución tórpida de enfermedad de Fabry en tratamiento con agalsidasa alfa: Presentación de un caso.

Fabry disease is characterized by the absence of activity of the lysosomal enzyme α-galactosidase A, which causes glycolipids, which should be broken down, to accumulate in the lysosomes of the cells of various tissues in the body, causing the signs and characteristic symptoms of this pathology. The severity of the disease depends on the level of mutation of the α-galactosidase A gene, which goes hand in hand with the age at presentation of symptoms, if we have a large mutation, we will have an earlier onset of it. For women, it is more frequent that the course of this condition is asymptomatic, most of them function as transmitters of Fabry disease, on the contrary, it has a predilection towards men. The most frequent clinical manifestations are angiokeratomas, acroparesthesias, anhidrosis, whorled cornea and in cases of death, they are related to kidney failure due to the progressive kidney failure it causes, heart failure or cerebrovascular disease. There is no cure for this deficiency, but we can stop its progress. For this purpose, two treatments have been developed: the first is enzyme replacement with agalsidase beta and the second with agalsidase alfa, whose effectiveness we will evaluate in a patient with Fabry disease compared to studies with enzyme replacement therapy with agalsidase betaLa enfermedad de Fabry se caracteriza por la ausencia de actividad de la enzima lisosomal α-galactosidasa A, lo cual provoca que los glucolípidos, los cuales deberían ser descompuestos, se acumulen en los lisosomas de las células de diversos tejidos en el cuerpo ocasionando los signos y síntomas característicos de esta patología. La gravedad de la enfermedad depende del nivel de mutación del gen de la α-galactosidasa A, lo cual va de la mano con la edad de presentación de los síntomas, si tenemos presencia de una gran mutación, tendremos un inicio más temprano de la misma. Para las mujeres es más frecuente que el curso de este padecimiento sea asintomático, en su mayoría actúan como transmisoras de la enfermedad de Fabry, por el contrario, tiene predilección hacia los hombres.  Las manifestaciones clínicas más frecuentes son angioqueratomas, acroparestesias, anhidrosis, córnea verticilada y en casos de fallecimiento, se relacionan con insuficiencia renal por el fallo renal progresivo que ocasiona, insuficiencia cardiaca o enfermedad cerebrovascular. Esta deficiencia no tiene cura, pero podemos frenar su avance, para ello se han desarrollado dos tratamientos principales: el primero la sustitución enzimática con agalsidasa beta y el segundo con agalsidasa alfa, del cual evaluaremos su efectividad en un paciente con enfermedad de Fabry en comparación a estudios con el tratamiento de reemplazo enzimático con agalsidasa bet

Fourier Analysis for Harmonic Signals in Electrical Power Systems

The harmonic content in electrical power systems is an increasingly worrying issue since the proliferation of nonlinear loads results in power quality problems as the harmonics is more apparent. In this paper, we analyze the behavior of the harmonics in the electrical power systems such as cables, transmission lines, capacitors, transformers, and rotating machines, the induction machine being the object of our study when it is excited to nonsinusoidal operating conditions in the stator winding. For this, a model is proposed for the harmonic analysis of the induction machine in steady‐state regimen applying the Fourier transform. The results of the proposed model are validated by experimental tests which gave good results for each case study concluding in a model proper for harmonic and nonharmonic analysis of the induction machine and for “harmonic” analysis in an electrical power system

Superposición de hepatitis B a hepatitis autoinmune. Diagnóstico y tratamiento, presentación de un caso clínico y revisión de casos clínicos en la literatura internacional

The hepatitis B virus represents one of the most frequent viral infections worldwide due to its easy transmission, in addition to this, its association with autoimmune pathologies has been found. This work will allow us to know the best treatment and most appropriate diagnostic method for its favorable clinical resolution. This systematic review was prepared in the database of Latin American and Caribbean Literature in Health Sciences, PubMed, and Google Scholar. The search was limited to studies carried out in humans, full texts, regardless of the language of writing or restriction of country of origin. A total of 133 articles were retrieved in the bibliographic search, of which 11 were excluded because they were duplicates, 71 articles were discarded because they contained brief information or only an ephemeral mention of the topic was made, 15 more were dispensed with in the Full review phase Text, 5 more for not being studies in humans and, finally, 10 opinions and perspectives, from which it was concluded that the treatment should be administered encompassing both pathologies to avoid clinical exacerbationEl virus de la hepatitis B representa una de las infecciones virales más frecuentes a nivel mundial dada su fácil forma de transmisión, aunado a esto, se ha encontrado su asociación a patologías autoinmunes. Este trabajo nos permitirá conocer el mejor tratamiento y método diagnóstico más adecuado para su resolución clínica favorable. Esta revisión sistemática se elaboró en la base de datos de Literatura Latinoamericana y del Caribe en Ciencias de la Salud, PubMed y de Google Scholar. La búsqueda fue delimitada a estudios realizados en humanos, textos completos, sin importar el idioma de escritura ni restricción de país de procedencia. Se recuperaron un total de 133 artículos en la búsqueda bibliográfica, de los cuales se excluyeron 11 por estar duplicados, 71 artículos fueron descartados por contener breve información o solo se realiza una mención efímera del tema, se prescindieron 15 más en la fase de revisión Full Text, 5 más por no ser estudios en humanos y, por último, 10 opiniones y perspectivas, de los cuales se concluyó que el tratamiento se debe administrar englobando ambas patologías para evitar la exacerbación clínica

Evento cerebrovascular en pacientes post COVID-19

Objective: The present study aims to determine the association and the factors involved between had suffered a COVID-19 event with the development of a cerebrovascular event. Methods: This is an observational, case-control, analytical, retrospective study with a 1:2 relation. Applied in the population of the Emergency Department, Internal Medicine, and Family Medicine, of the General Hospital Zone with Family Medicine No. 32 of Minatitlan Veracruz. Results: A final sample of 111 cases and 222 controls was obtained. The average age is 58 years ±17.6. Of the total number of patients, 126 (37.8%) were men and 207 (62.2%) were women. 159 patients (47.74%) had a positive history of COVID-19. An Odds Ratio of 1.38 (95%; 0.876 – 2.186) was found. The age of the patients, the severity of the infection in its acute phase, the level of severity of the cerebrovascular event and the history of vaccination were statistically significant results. Conclusion: COVID-19 is associated as an independent factor with the development of a cerebrovascular event.Objetivo: El presente estudio pretende determinar la asociación y factores implicados entre haber padecido un evento de COVID-19 con el desarrollo de un evento cerebrovascular. Métodos: Es un estudio observacional, de casos y controles, analítico, retrospectivo, con relación 1:2. Aplicado en la población del servicio de Urgencias, Medicina interna y Medicina familiar, del Hospital General de Zona con Medicina Familiar N° 32 de Minatitlán Veracruz. Resultados: Se obtuvo una muestra final de 111 casos y 222 controles. El promedio de edad es de 58 años ±17.6. Del total de pacientes 126 (37.8%) son hombres y 207 (62.2%) son mujeres. 159 pacientes (47.74%) tuvieron antecedente positivo de COVID-19. Se encontró un Odds Ratio de 1.38 (95%; 0.876 – 2.186). La edad de los pacientes, la gravedad de la infección en su fase aguda, el nivel de gravedad del evento cerebrovascular y el antecedente de vacuna, fueron resultados estadísticamente significativos. Conclusión: El COVID-19 se encuentra asociado como factor independiente al desarrollo de evento cerebrovascular

Allergen sensitization linked to climate and age, not to intermittent-persistent rhinitis in a cross-sectional cohort study in the (sub)tropics

Background: Allergen exposure leads to allergen sensitization in susceptible individuals and this might influence allergic rhinitis (AR) phenotype expression. We investigated whether sensitization patterns vary in a country with subtropical and tropical regions and if sensitization patterns relate to AR phenotypes or age. Methods: In a national, cross-sectional study AR patients (2-70 y) seen by allergists underwent blinded skin prick testing with a panel of 18 allergens and completed a validated questionnaire on AR phenotypes. Results: 628 patients were recruited. The major sensitizing allergen was house dust mite (HDM) (56%), followed by Bermuda grass (26%), ash (24%), oak (23%) and mesquite (21%) pollen, cat (22%) and cockroach (21%). Patients living in the tropical region were almost exclusively sensitized to HDM (87%). In the central agricultural zones sensitization is primarily to grass and tree pollen. Nationwide, most study subjects had perennial (82.2%), intermittent (56.5%) and moderate-severe (84.7%) AR. Sensitization was not related to the intermittent-persistent AR classification or to AR severity; seasonal AR was associated with tree (p < 0.05) and grass pollen sensitization (p < 0.01). HDM sensitization was more frequent in children (0-11 y) and adolescents (12-17 y) (subtropical region: p < 0.0005; tropical region p < 0.05), but pollen sensitization becomes more important in the adult patients visiting allergists (Adults vs children + adolescents for tree pollen: p < 0.0001, weeds: p < 0.0005). Conclusions: In a country with (sub)tropical climate zones SPT sensitization patterns varied according to climatological zones; they were different from those found in Europe, HDM sensitization far outweighing pollen allergies and Bermuda grass and Ash pollen being the main grass and tree allergens, respectively. Pollen sensitization was related to SAR, but no relation between sensitization and intermittent-persistent AR or AR severity could be detected. Sensitization patterns vary with age (child HDM, adult pollen). Clinical implications of our findings are dual: only a few allergens –some region specific- cover the majority of sensitizations in (sub)tropical climate zones. This is of major importance for allergen manufacturers and immunotherapy planning. Secondly, patient selection in clinical trials should be based on the intermittent-persistent and severity classifications, rather than on the seasonal-perennial AR subtypes, especially when conducted in (sub)tropical countries

Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements

Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an

Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis

Differential cross section measurements for the production of a W boson in association with jets in proton–proton collisions at √s = 7 TeV

Measurements are reported of differential cross sections for the production of a W boson, which decays into a muon and a neutrino, in association with jets, as a function of several variables, including the transverse momenta (pT) and pseudorapidities of the four leading jets, the scalar sum of jet transverse momenta (HT), and the difference in azimuthal angle between the directions of each jet and the muon. The data sample of pp collisions at a centre-of-mass energy of 7 TeV was collected with the CMS detector at the LHC and corresponds to an integrated luminosity of 5.0 fb[superscript −1]. The measured cross sections are compared to predictions from Monte Carlo generators, MadGraph + pythia and sherpa, and to next-to-leading-order calculations from BlackHat + sherpa. The differential cross sections are found to be in agreement with the predictions, apart from the pT distributions of the leading jets at high pT values, the distributions of the HT at high-HT and low jet multiplicity, and the distribution of the difference in azimuthal angle between the leading jet and the muon at low values.United States. Dept. of EnergyNational Science Foundation (U.S.)Alfred P. Sloan Foundatio