GridWeaver: A Fully-Automatic System for Microarray Image Analysis Using Fast Fourier Transforms

Experiments using microarray technology generate large amounts of image data that are used in the analysis of genetic function. An important stage in the analysis is the determination of relative intensities of spots on the images generated. This paper presents GridWeaver, a program that reads in images from a microarray experiment, automatically locates subgrids and spots in the images, and then determines the spot intensities needed in the analysis of gene function. Automatic gridding is performed by running Fast Fourier Transforms on pixel intensity sums. Tests on several data sets show that the program responds well even on images that have significant noise, both random and systemic

Cryospheric Study in the GRENE-Arctic Climate Change Research Project

第4回極域科学シンポジウム横断セッション：[IA] 「急変する北極気候システム及びその全球的な影響の総合的解明」―GRENE北極気候変動研究事業研究成果報告2013―11月12日（火） 国立極地研究所 ２階大会議

Transcriptome-wide functional characterization reveals novel relationships among differentially expressed transcripts in developing soybean embryos

Sense and antisense transcripts and primers chosen for validation of RNA-Seq-based expression level changes. Sense and antisense transcripts are shown with the corresponding annotation, primer pairs used for qPCR, time points of differential expression, and notes on the presence of additional melt curve peaks. (PPTX 39 kb

An outline of GRENE research project 5 entitiled “Studies on greenhouse gas cycles in the Arctic and their responses to climate change"

第3回極域科学シンポジウム/特別セッション「これからの北極研究」11月28日（水） 国立極地研究所 2階大会議

Two Electrons in a Quantum Dot: A Unified Approach

Low-lying energy levels of two interacting electrons confined in a two-dimensional parabolic quantum dot in the presence of an external magnetic field have been revised within the frame of a novel model. The present formalism, which gives closed algebraic solutions for the specific values of magnetic field and spatial confinement length, enables us to see explicitly individual effects of the electron correlation.Comment: 14 page

Pierse, Mary (ed.), George Moore: Artistic Visions and Literary Worlds.

Pierse, Mary (ed.), George Moore: Artistic Visions and Literary Worlds. Newcastle: Cambridge Scholars Press, 2006, xvii + 246 pp

Grounding knowledge and normative valuation in agent-based action and scientific commitment

Philosophical investigation in synthetic biology has focused on the knowledge-seeking questions pursued, the kind of engineering techniques used, and on the ethical impact of the products produced. However, little work has been done to investigate the processes by which these epistemological, metaphysical, and ethical forms of inquiry arise in the course of synthetic biology research. An attempt at this work relying on a particular area of synthetic biology will be the aim of this chapter. I focus on the reengineering of metabolic pathways through the manipulation and construction of small DNA-based devices and systems synthetic biology. Rather than focusing on the engineered products or ethical principles that result, I will investigate the processes by which these arise. As such, the attention will be directed to the activities of practitioners, their manipulation of tools, and the use they make of techniques to construct new metabolic devices. Using a science-in-practice approach, I investigate problems at the intersection of science, philosophy of science, and sociology of science. I consider how practitioners within this area of synthetic biology reconfigure biological understanding and ethical categories through active modelling and manipulation of known functional parts, biological pathways for use in the design of microbial machines to solve problems in medicine, technology, and the environment. We might describe this kind of problem-solving as relying on what Helen Longino referred to as “social cognition” or the type of scientific work done within what Hasok Chang calls “systems of practice”. My aim in this chapter will be to investigate the relationship that holds between systems of practice within metabolic engineering research and social cognition. I will attempt to show how knowledge and normative valuation are generated from this particular network of practitioners. In doing so, I suggest that the social nature of scientific inquiry is ineliminable to both knowledge acquisition and ethical evaluations

Readings of Reading: Purpose and Process in Teaching Literature

What do we hope to teach in teaching literature, and how can we best serve that purpose? These are questions that are no less urgent than they are fundamental, and should, in fact, be constantly in our minds as we engage in our practice. This discussion will entail a conversation between the theories behind, and the process of, teaching literature to adolescents, with a series of observations and thoughts rooted in specific texts and classes. I will start by querying how we define our mission, and then situate this debate in its historical context. I will look at how current influences are affecting this mission, before examining in a more granular sense how we attempt to trace progress and process. I will root this discussion in both theory and practice, utilizing my own teaching and extant student artifacts. I will argue that the elliptical nature of the process means that our assessment must be multifaceted, and that a mirror elliptical approach on our end can yield richer understandings, for both teacher and students

Constitutivism

A brief explanation and overview of constitutivism