798 research outputs found

    Bienestar y familia, una mirada desde la psicologĂ­a positiva

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    Este libro estĂĄ dirigido a estudiantes y profesionales en psicologĂ­a y ĂĄreas afines, como enfermerĂ­a, trabajo social o educaciĂłn, y a los interesados en personalidad positiva. Cada capĂ­tulo se presenta de manera sencilla y con una estructura didĂĄctica, pero sin perder rigor cientĂ­fico y calidad de la revisiĂłn, con el fin de facilitar el acceso a la informaciĂłn sobre bienestar individual, familiar y social de una forma accesible para adentrarnos al estudio de temas de psicologĂ­a positiva. Dadas las temĂĄticas, se considerĂł pertinente dividir este libro en dos secciones: I. PsicologĂ­a positiva y bienestar. II. Bienestar individual y familiar.Universidad AutĂłnoma del Estado de MĂ©xico y Ediciones y GrĂĄficos EĂłn, S.A. de C.V

    DesafĂ­os de las metrĂłpolis: Efectos ambientales y sociales. Tendencias geogrĂĄficas II

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    El libro estå conformado de estudios realizados por profesores-investigadores de la Universidad Autónoma del Estado de México, de la Universidad de Varsovia, así como de la Universidad Pedagógica Comisión de Educación Nacional de Cracovia. En esta obra se exponen algunas investigaciones sobre los cambios en los factores sociales, naturales, económicos y ambientales como principales desafios que presentan las zonas de México, Polonia y de contextos de Sudamérica, tales como Sao Paulo, Quito y Bogotå y ciudades medias y pequeñas.Universidad Autónoma del Estado de Méxic

    Long-term thermal sensitivity of Earth’s tropical forests

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    The sensitivity of tropical forest carbon to climate is a key uncertainty in predicting global climate change. Although short-term drying and warming are known to affect forests, it is unknown if such effects translate into long-term responses. Here, we analyze 590 permanent plots measured across the tropics to derive the equilibrium climate controls on forest carbon. Maximum temperature is the most important predictor of aboveground biomass (−9.1 megagrams of carbon per hectare per degree Celsius), primarily by reducing woody productivity, and has a greater impact per °C in the hottest forests (>32.2°C). Our results nevertheless reveal greater thermal resilience than observations of short-term variation imply. To realize the long-term climate adaptation potential of tropical forests requires both protecting them and stabilizing Earth’s climate

    Photography-based taxonomy is inadequate, unnecessary, and potentially harmful for biological sciences

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    The question whether taxonomic descriptions naming new animal species without type specimen(s) deposited in collections should be accepted for publication by scientific journals and allowed by the Code has already been discussed in Zootaxa (Dubois & NemĂ©sio 2007; Donegan 2008, 2009; NemĂ©sio 2009a–b; Dubois 2009; Gentile & Snell 2009; Minelli 2009; Cianferoni & Bartolozzi 2016; Amorim et al. 2016). This question was again raised in a letter supported by 35 signatories published in the journal Nature (Pape et al. 2016) on 15 September 2016. On 25 September 2016, the following rebuttal (strictly limited to 300 words as per the editorial rules of Nature) was submitted to Nature, which on 18 October 2016 refused to publish it. As we think this problem is a very important one for zoological taxonomy, this text is published here exactly as submitted to Nature, followed by the list of the 493 taxonomists and collection-based researchers who signed it in the short time span from 20 September to 6 October 2016

    Identification of regulatory variants associated with genetic susceptibility to meningococcal disease.

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    Non-coding genetic variants play an important role in driving susceptibility to complex diseases but their characterization remains challenging. Here, we employed a novel approach to interrogate the genetic risk of such polymorphisms in a more systematic way by targeting specific regulatory regions relevant for the phenotype studied. We applied this method to meningococcal disease susceptibility, using the DNA binding pattern of RELA - a NF-kB subunit, master regulator of the response to infection - under bacterial stimuli in nasopharyngeal epithelial cells. We designed a custom panel to cover these RELA binding sites and used it for targeted sequencing in cases and controls. Variant calling and association analysis were performed followed by validation of candidate polymorphisms by genotyping in three independent cohorts. We identified two new polymorphisms, rs4823231 and rs11913168, showing signs of association with meningococcal disease susceptibility. In addition, using our genomic data as well as publicly available resources, we found evidences for these SNPs to have potential regulatory effects on ATXN10 and LIF genes respectively. The variants and related candidate genes are relevant for infectious diseases and may have important contribution for meningococcal disease pathology. Finally, we described a novel genetic association approach that could be applied to other phenotypes

    Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome : Insights from the LUNG SAFE study

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    Publisher Copyright: © 2020 The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.Background: Concerns exist regarding the prevalence and impact of unnecessary oxygen use in patients with acute respiratory distress syndrome (ARDS). We examined this issue in patients with ARDS enrolled in the Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE (LUNG SAFE) study. Methods: In this secondary analysis of the LUNG SAFE study, we wished to determine the prevalence and the outcomes associated with hyperoxemia on day 1, sustained hyperoxemia, and excessive oxygen use in patients with early ARDS. Patients who fulfilled criteria of ARDS on day 1 and day 2 of acute hypoxemic respiratory failure were categorized based on the presence of hyperoxemia (PaO2 > 100 mmHg) on day 1, sustained (i.e., present on day 1 and day 2) hyperoxemia, or excessive oxygen use (FIO2 ≄ 0.60 during hyperoxemia). Results: Of 2005 patients that met the inclusion criteria, 131 (6.5%) were hypoxemic (PaO2 < 55 mmHg), 607 (30%) had hyperoxemia on day 1, and 250 (12%) had sustained hyperoxemia. Excess FIO2 use occurred in 400 (66%) out of 607 patients with hyperoxemia. Excess FIO2 use decreased from day 1 to day 2 of ARDS, with most hyperoxemic patients on day 2 receiving relatively low FIO2. Multivariate analyses found no independent relationship between day 1 hyperoxemia, sustained hyperoxemia, or excess FIO2 use and adverse clinical outcomes. Mortality was 42% in patients with excess FIO2 use, compared to 39% in a propensity-matched sample of normoxemic (PaO2 55-100 mmHg) patients (P = 0.47). Conclusions: Hyperoxemia and excess oxygen use are both prevalent in early ARDS but are most often non-sustained. No relationship was found between hyperoxemia or excessive oxygen use and patient outcome in this cohort. Trial registration: LUNG-SAFE is registered with ClinicalTrials.gov, NCT02010073publishersversionPeer reviewe

    TRY plant trait database – enhanced coverage and open access

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    Plant traits - the morphological, anatomical, physiological, biochemical and phenological characteristics of plants - determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodiversity conservation, ecosystem and landscape management, restoration, biogeography and earth system modelling. Since its foundation in 2007, the TRY database of plant traits has grown continuously. It now provides unprecedented data coverage under an open access data policy and is the main plant trait database used by the research community worldwide. Increasingly, the TRY database also supports new frontiers of trait‐based plant research, including the identification of data gaps and the subsequent mobilization or measurement of new data. To support this development, in this article we evaluate the extent of the trait data compiled in TRY and analyse emerging patterns of data coverage and representativeness. Best species coverage is achieved for categorical traits - almost complete coverage for ‘plant growth form’. However, most traits relevant for ecology and vegetation modelling are characterized by continuous intraspecific variation and trait–environmental relationships. These traits have to be measured on individual plants in their respective environment. Despite unprecedented data coverage, we observe a humbling lack of completeness and representativeness of these continuous traits in many aspects. We, therefore, conclude that reducing data gaps and biases in the TRY database remains a key challenge and requires a coordinated approach to data mobilization and trait measurements. This can only be achieved in collaboration with other initiatives

    Aplicaciones electroquĂ­micas al tratamiento de aguas residuales

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    El presente libro tiene como finalidad compilar numerosas investigaciones en el campo de la tecnologĂ­a electroquĂ­mica y sus aplicaciones ambientales, contando con la colaboraciĂłn de un gran nĂșmero de investigadores tanto nacionales como extranjeros, proponiendo con ello una visiĂłn amplia dentro de la aplicaciĂłn de la electroquĂ­mica. Los temas que integran esta obra se escogieron cuidadosamente considerando desde los principios bĂĄsicos de la electroquĂ­mica aplicada al tratamiento de aguas residuales hasta los parĂĄmetros a considerar durante el diseño, operaciĂłn y evaluaciĂłn de dichos sistemas, sin dejar de lado las aplicaciones utilizadas en la actualidad en la industria, la docencia y la investigaciĂłn. Este libro reĂșne diversas temĂĄticas por lo que puede considerarse como un compendio de aquellos elementos que el lector requiere para poder tener una visiĂłn amplia de las aplicaciones de la electroquĂ­mica en el campo del tratamiento de agua residual.En el CapĂ­tulo 1 se presenta una primera impresiĂłn de los Fundamentes de la ElectroquĂ­mica Ambiental, en donde los autores explican cĂłmo esta disciplina es una nueva ĂĄrea de la ciencia en donde se emplean conocimientos de ElectroquĂ­mica, IngenierĂ­a QuĂ­mica y Ciencia de Materiales, asĂ­ como las aplicaciones especĂ­ficas para la remediaciĂłn ambiental. En el CapĂ­tulo 2 los autores ofrecen una descripciĂłn de los principales parĂĄmetros fisicoquĂ­micos y biolĂłgicos que se emplean para definir a la calidad del agua. Este capĂ­tulo describe en funciĂłn de quĂ© caracterĂ­sticas fĂ­sicas, quĂ­micas y biolĂłgicas se puede evaluar a un agua residual asĂ­ como tambiĂ©n la aplicaciĂłn de estas caracterĂ­sticas como variables de control de un proceso de tratamiento y tambiĂ©n como el empleo de ellas para limitar las concentraciones mĂĄximas permisibles de descarga de aguas residuales. El CapĂ­tulo 3 se refiere a uno de los procesos mĂĄs empleados en el tratamiento de agua: la coagulaciĂłn-floculaciĂłn. Se aborda desde una Ăłptica teĂłrica hasta la descripciĂłn de un ejemplo de aplicaciĂłn en la industria. Resulta importante incluir este capĂ­tulo ya que uno de los mĂ©todos mĂĄs prometedores en la electroquĂ­mica ambiental es la electrocoagulaciĂłn, la cual se narra en el CapĂ­tulo 6. Las bases de las celdas de laboratorio y reactores industriales electroquĂ­micos se relatan en el CapĂ­tulo 4. En particular, se refieren las implicaciones que tienen las principales caracterĂ­sticas fĂ­sicas y de diseño de celdas de laboratorio y reactores electroquĂ­micos industriales que permiten obtener transformaciones eficientes gracias a un correcto control del potencial de electrodo en estos sistemas. La implementaciĂłn de procesos electroquĂ­micos para su aplicaciĂłn a nivel industrial, requiere del diseño eficiente del dispositivo central: el reactor electroquĂ­mico. Por lo que, en el CapĂ­tulo 5 se presentan los elementos de anĂĄlisis de reactores electroquĂ­micos para su diseño y caracterizaciĂłn. El CapĂ­tulo 7 describe bajo quĂ© circunstancias se puede llevar a cabo el proceso de electroflotaciĂłn. Los autores muestran cĂłmo este proceso estĂĄ influenciado por el pH de la soluciĂłn acuosa, la densidad de corriente y el tipo de electrodos que se emplean. El lector encontrarĂĄ en el CapĂ­tulo 8 las bases teĂłricas de uno de los procesos que involucra la quĂ­mica de la reacciĂłn de Fenton, asĂ­ como las aplicaciones ambientales para el tratamiento de soluciones sintĂ©ticas y reales con diferentes contaminantes refractarios, tales como plaguicidas, colorantes, productos de cuidado personal, fĂĄrmacos y residuos quĂ­micos industriales. En el CapĂ­tulo 9 se presentan algunos conceptos fundamentales sobre la ElectrooxidaciĂłn, tambiĂ©n conocida como oxidaciĂłn electroquĂ­mica, la cual estĂĄ enfocada a realizar la oxidaciĂłn de contaminantes presentes en aguas residuales sobre la superficie de electrodos. La tecnologĂ­a para la electrogeneraciĂłn de perĂłxido de hidrĂłgeno y su empleo en el tratamiento de agua residual se describe en el CapĂ­tulo 10. Uno de los metales pesados que tienen un alto grado de toxicidad en el ambiente es el Cr(VI), el cual no puede ser removido por mĂ©todos convencionales por lo que una tecnologĂ­a que puede emplearse en este tratamiento se relata en el CapĂ­tulo 11. En el CapĂ­tulo 12 se presentan los avances mĂĄs recientes cuando se emplean los mĂ©todos electroquĂ­micos con algĂșn otro tipo de tratamiento, lo que ha resultado en la obtenciĂłn de sinergias en los procesos, lo que implica una reducciĂłn en los costos de operaciĂłn. Finalmente, en el CapĂ­tulo 13, se presenta el tema de usos y aplicaciones de sensores quĂ­micos y electroquĂ­micos para la detecciĂłn de contaminantes en agua y agua residual

    Search for new particles in events with energetic jets and large missing transverse momentum in proton-proton collisions at root s=13 TeV

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    A search is presented for new particles produced at the LHC in proton-proton collisions at root s = 13 TeV, using events with energetic jets and large missing transverse momentum. The analysis is based on a data sample corresponding to an integrated luminosity of 101 fb(-1), collected in 2017-2018 with the CMS detector. Machine learning techniques are used to define separate categories for events with narrow jets from initial-state radiation and events with large-radius jets consistent with a hadronic decay of a W or Z boson. A statistical combination is made with an earlier search based on a data sample of 36 fb(-1), collected in 2016. No significant excess of events is observed with respect to the standard model background expectation determined from control samples in data. The results are interpreted in terms of limits on the branching fraction of an invisible decay of the Higgs boson, as well as constraints on simplified models of dark matter, on first-generation scalar leptoquarks decaying to quarks and neutrinos, and on models with large extra dimensions. Several of the new limits, specifically for spin-1 dark matter mediators, pseudoscalar mediators, colored mediators, and leptoquarks, are the most restrictive to date.Peer reviewe

    Combined searches for the production of supersymmetric top quark partners in proton-proton collisions at root s=13 TeV

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    A combination of searches for top squark pair production using proton-proton collision data at a center-of-mass energy of 13 TeV at the CERN LHC, corresponding to an integrated luminosity of 137 fb(-1) collected by the CMS experiment, is presented. Signatures with at least 2 jets and large missing transverse momentum are categorized into events with 0, 1, or 2 leptons. New results for regions of parameter space where the kinematical properties of top squark pair production and top quark pair production are very similar are presented. Depending on themodel, the combined result excludes a top squarkmass up to 1325 GeV for amassless neutralino, and a neutralinomass up to 700 GeV for a top squarkmass of 1150 GeV. Top squarks with masses from 145 to 295 GeV, for neutralino masses from 0 to 100 GeV, with a mass difference between the top squark and the neutralino in a window of 30 GeV around the mass of the top quark, are excluded for the first time with CMS data. The results of theses searches are also interpreted in an alternative signal model of dark matter production via a spin-0 mediator in association with a top quark pair. Upper limits are set on the cross section for mediator particle masses of up to 420 GeV
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