Extended files for "The Missing Billion: Using participatory approaches to improve access to healthcare for disabled people in Uganda"

Extended files for the formative research conducted under the Missing Billion project in Uganda, which focused on designing and testing community-based, participatory approaches to make healthcare more inclusive and accessible. This formative work contributed evidence to inform the design, content, and implementation of disability-inclusive health interventions, including the structure and function of Participatory Disability Action Groups

Data for "Life course malaria exposure and SARS-CoV-2 Sero-epidemiology in Ugandan adolescents: a longitudinal study nested in a birth cohort"

This data was collected from a longitudinal study nested within the Entebbe Mother and Baby Study birth cohort in Uganda. Adolescents were enrolled and followed up 6 and 12 months later. Blood samples were collected at each visit for SARS-CoV-2 serology. Malaria exposure was defined using prospectively collected data on clinical malaria (from birth to 10 years), asymptomatic parasitaemia at annual visits, and antibody responses to Plasmodium falciparum merozoite surface protein 2 (PfMSP-2) and apical membrane antigen 1 (PfAMA-1). The primary outcome was SARS-CoV-2 seropositivity, based on spike and nucleocapsid IgG responses, with seropositivity cut-offs derived from pre-pandemic samples. Secondary outcomes, including antibody concentrations and symptomatic PCR-confirmed disease, were explored

Global Dengue Observatory

The Global Dengue Observatory draws together the latest data from 88 countries around the world to estimate the current number of dengue cases each month at a national and continental level

Maximum likelihood estimation of phylogenetic branch lengths for a star-like phylogeny

R code to calculate maximum likelihood branch lengths for a star-like tree with a gamma rate distribution

Clinical codelists: Frailty progression following severe infections in adults ≥65 years in US and England: two matched cohort studies

A set of clinical codelist used to define infection (exposure), frailty (outcome), and other covariates in a cohort study on frailty progression following severe infections in adults aged over 65 years in US and England

Data file for the presented analysis in "Acceptability of COVID-19 self-testing among social and clinical vulnerable populations using a decentralized testing model in Abuja, Nigeria; A mixed methods analysis of an implementation study"

Diagnostic testing is critical during infectious disease outbreaks, enabling timely patient management and isolation to reduce transmission and mortality. During the COVID-19 outbreak in Nigeria, testing rates remained low due to limited access to centralized RT-PCR sites. To expand access, the National COVID-19 Testing Strategy (January 2021) introduced decentralized self-testing models targeting vulnerable populations. This study assessed the uptake of decentralized COVID-19 testing and the acceptability of self-testing among socially and clinically vulnerable populations in Abuja, Nigeria. A mixed-methods study was conducted across four primary health centres (PHC), four community pharmacies (CP), and four patent medicine stores (PMS) between October 2022 and May 2023. Symptomatic individuals received provider-delivered testing at PHC or provider-delivered/self-testing at CP and PMS using antigen rapid diagnostic tests (Ag-RDT). Social vulnerability was defined by low education, illiteracy, or low wealth; clinical vulnerability by age ≥ 50, unvaccinated status, or comorbidities. Testing uptake and acceptability were analyzed using logistic regression, while in-depth interviews (IDI) explored preferences for testing sites and methods. Of 1,586 individuals screened, 1,368 were eligible and 1,322 (96.6%) accepted testing. Most tests occurred at PHC (53.5%), followed by PMS (25.9%) and CP (20.7%). Social vulnerability was higher among PMS users than PHC users (OR = 1.37; 95% CI 1.05–1.77), while clinical vulnerability was lower at CP (OR = 0.24; 95% CI 0.16–0.35) and PMS (OR = 0.28; 95% CI 0.19–0.39) compared to PHC. Self-testing acceptability was high (93.4% at CP; 92.1% at PMS). Outcome of IDI highlighted trust in CP/PMS providers, proximity, convenience, and affordability as key drivers of testing uptake, with self-testing widely preferred across vulnerability groups. Decentralized testing through CP and PMS reached more socially vulnerable individuals and demonstrated high self-testing acceptability. Leveraging these outlets in outbreak responses could enhance equitable access to diagnostic testing in future pandemics

Codelists for: "Infections and risk of mental health conditions: a series of population-based matched cohort studies using linked electronic health records"

A set of 91 codelists associated with three studies: (1) Infections and risk of common mental health disorders: a population-based matched cohort study using linked electronic health records; (2) Infections and risk of severe mental illness: a population-based matched cohort study, and (3) Infections and suicide and self-harm: a population-based matched cohort study

Clinical codelist - Abdominal mass

Clinical codelist for GOLD and Aurum medcodes

Clinical codelist - Hypertension

Clinical codelist for GOLD and Aurum medcodes on Hypertension

Rapid Assessment of Avoidable Blindness Report: Vietnam, Phu Tho (2007)

A report including output of standardised analysis of vision and eye health survey data including tables of vision impairment prevalence and service coverage estimates