La expresión de las emociones en relación al factor victoria durante la práctica de juegos deportivos

Este estudio tiene como objeto describir la relación entre la práctica de diferentes tipos de juegos motores reglamentados (juegos deportivos con o sin competición) y la expresión de las emociones. Los participantes fueron 726 estudiantes de actividad física y deportes del primer curso de facultades, escuelas de formación del profesorado y de animación deportiva de España y Portugal, a los que previamente se formó en la toma de conciencia en la expresión de las emociones. Realizaron ocho juegos deportivos correspondientes a los cuatro dominios de acción (psicomotriz (en solitario), cooperación, oposición y cooperación/oposición), siendo uno de cada de competición (lo cual implica la victoria o derrota de los participantes) y otro sin competición (nadie gana o pierde). Tras la realización de cada juego el participante registró en un cuestionario validado (Games and Emotions Scale (GES)) la intensidad alcanzada en cada una de las 13 emociones (clasificadas como positivas, negativas y ambiguas). Los resultados (tratamiento estadístico mediante ecuaciones de estimación generalizadas) muestran que la intensidad de las emociones positivas fueron en todos los juegos siempre muy superiores en comparación a la intensidad de las negativas y ambiguas. Ello nos puede confirmar el disfrute durante la práctica de los juegos deportivos. Dicho esto, se observa, por un lado, que la intensidad de las emociones positivas son ligeramente superiores en los juegos sin competición y, por otro lado, que la intensidad de las emociones es superior en la competición en comparación a los juegos sin competición, pero que esta superioridad se debe sobre todo a las emociones negativas y ambiguas. La medición, comparación, victoria y derrota inherentes a la competición puede tender a incrementar la frustración y el rechazo. Por último, se aprecian diferencias significativas entre los cuatro dominios al considerar si existe o no la victoria, especialmente para juegos cooperativos sin competición, donde la intensidad de las emociones positivas sube más que en los otros tipos de juegos y las negativas bajan, confirmando la conveniencia de los juegos cooperativos no competitivos en los programas educativos, reeducativos y recreativos, donde la superación del reto es una tarea colectiv

Exceptional del Pezzo hypersurfaces

We compute global log canonical thresholds of a large class of quasismooth well-formed del Pezzo weighted hypersurfaces in $\mathbb{P}(a_{1},a_{2},a_{3},a_{4})$. As a corollary we obtain the existence of orbifold K\"ahler--Einstein metrics on many of them, and classify exceptional and weakly exceptional quasismooth well-formed del Pezzo weighted hypersurfaces in $\mathbb{P}(a_{1},a_{2},a_{3},a_{4})$.Comment: 149 pages, one reference adde

The role of antimicrobial stewardship programmes in children: a systematic review.

The United Nations and the World Health Organization have designated antimicrobial resistance (AMR) as a major health priority and developed action plans to reduce AMR in all healthcare settings. Establishment of institutional antimicrobial stewardship programmes (ASPs) is advocated as a key intervention to reduce antibiotic consumption in hospitals and address high rates of multi-drug resistant (MDR) bacteria. We searched PUBMED and the Cochrane database of systematic reviews (1/2007-3/2017) to identify studies reporting about the effectiveness of ASPs in general paediatric wards and paediatric intensive care units (PICU), on reducing antibiotic consumption, on using broad spectrum/restricted antibiotics, and on antibiotic resistance and healthcare-associated infections (HAIs). Neonatal units and antifungal agents were excluded. Of 2509 titles and abstracts, nine articles were eligible to be included in the final analysis. All studies reported on the reduction of broad spectrum/restricted antibiotics or antibiotic consumption. One study reported on the reduction of HAI in a PICU, and another evaluated bacterial resistance, showing no effect following ASP implementation. Prospective audit on antibiotic use was the most common ASP core component (eight of nine studies). Antibiotic pre-authorisation was described in two articles. Other described interventions were providing guidelines or written information (five of nine articles), and training of healthcare professionals (one article). There is limited evidence about reducing antibiotic consumption and broad-spectrum/restricted agents following ASP implementation, specifically in PICU. Data evaluating the impact of ASPs on HAI and AMR in PICU is lacking. In addition, there is limited information on effective components of a successful ASPs in PICUs

Trace element composition of silicate inclusions in sub-lithospheric diamonds from the Juina-5 kimberlite:Evidence for diamond growth from slab melts

The trace element compositions of inclusions in sub-lithospheric diamonds from the Juina-5 kimberlite, Brazil, are presented. Literature data for mineral/melt partition coefficients were collated, refitted and employed to interpret inclusion compositions. As part of this process an updated empirical model for predicting the partitioning behaviour of trivalent cations for garnet–melt equilibrium calibrated using data from 73 garnet-melt pairs is presented. High levels of trace element enrichment in inclusions interpreted as former calcium silicate perovskite and majoritic garnet preclude their origin as fragments of an ambient deep mantle assemblage. Inclusions believed to represent former bridgmanite minerals also display a modest degree of enrichment relative to mantle phases. The trace element compositions of ‘NAL’ and ‘CF phase’ minerals are also reported. Negative Eu, Ce, and Y/Ho anomalies alongside depletions of Sr, Hf and Zr in many inclusions are suggestive of formation from a low-degree carbonatitic melt of subducted oceanic crust. Observed enrichments in garnet and ‘calcium perovskite’ inclusions limit depths of melting to less than ~ 600 km, prior to calcium perovskite saturation in subducting assemblages. Less enriched inclusions in sub-lithospheric diamonds from other global localities may represent deeper diamond formation. Modelled source rock compositions that are capable of producing melts in equilibrium with Juina-5 ‘calcium perovskite’ and majorite inclusions are consistent with subducted MORB. Global majorite inclusion compositions suggest a common process is responsible for the formation of many superdeep diamonds, irrespective of geographic locality. Global transition zone inclusion compositions are reproduced by fractional crystallisation from a single parent melt, suggesting that they record the crystallisation sequence and melt evolution during this interaction of slab melts with ambient mantle. All observations are consistent with the previous hypothesis that many superdeep diamonds are created as slab-derived carbonatites interact with peridotitic mantle in the transition zone

Search for black holes and other new phenomena in high-multiplicity final states in proton-proton collisions at root s=13 TeV

Peer reviewe

Measurement of the cross section for isolated-photon plus jet production in pp collisions at √s=13 TeV using the ATLAS detector

The dynamics of isolated-photon production in association with a jet in proton–proton collisions at a centre-of-mass energy of 13 TeV are studied with the ATLAS detector at the LHC using a dataset with an integrated luminosity of 3.2 fb−1. Photons are required to have transverse energies above 125 GeV. Jets are identified using the anti- algorithm with radius parameter and required to have transverse momenta above 100 GeV. Measurements of isolated-photon plus jet cross sections are presented as functions of the leading-photon transverse energy, the leading-jet transverse momentum, the azimuthal angular separation between the photon and the jet, the photon–jet invariant mass and the scattering angle in the photon–jet centre-of-mass system. Tree-level plus parton-shower predictions from Sherpa and Pythia as well as next-to-leading-order QCD predictions from Jetphox and Sherpa are compared to the measurements

A search for resonances decaying into a Higgs boson and a new particle X in the XH → qqbb final state with the ATLAS detector

A search for heavy resonances decaying into a Higgs boson (H) and a new particle (X) is reported, utilizing 36.1 fb−1 of proton–proton collision data at collected during 2015 and 2016 with the ATLAS detector at the CERN Large Hadron Collider. The particle X is assumed to decay to a pair of light quarks, and the fully hadronic final state is analysed. The search considers the regime of high XH resonance masses, where the X and H bosons are both highly Lorentz-boosted and are each reconstructed using a single jet with large radius parameter. A two-dimensional phase space of XH mass versus X mass is scanned for evidence of a signal, over a range of XH resonance mass values between 1 TeV and 4 TeV, and for X particles with masses from 50 GeV to 1000 GeV. All search results are consistent with the expectations for the background due to Standard Model processes, and 95% CL upper limits are set, as a function of XH and X masses, on the production cross-section of the resonance

First-in-class Microbial Ecosystem Therapeutic 4 (MET4) in combination with immune checkpoint inhibitors in patients with advanced solid tumors (MET4-IO trial)

Background: The intestinal microbiome has been associated with response to immune checkpoint inhibitors (ICIs) in humans and causally implicated in ICI responsiveness in animal models. Two recent human trials demonstrated that fecal microbiota transplant (FMT) from ICI responders can rescue ICI responses in refractory melanoma, but FMT has specific limitations to scaled use.Patients and methods: We conducted an early-phase clinical trial of a cultivated, orally delivered 30-species microbial consortium (Microbial Ecosystem Therapeutic 4, MET4) designed for co-administration with ICIs as an alternative to FMT and assessed safety, tolerability and ecological responses in patients with advanced solid tumors.Results: The trial achieved its primary safety and tolerability outcomes. There were no statistically significant differences in the primary ecological outcomes; however, differences in MET4 species relative abundance were evident after randomization that varied by patient and species. Increases in the relative abundance of several MET4 taxa, including Enterococcus and Bifidobacterium, taxa previously associated with ICI responsiveness, were observed and MET4 engraftment was associated with decreases in plasma and stool primary bile acids.Conclusions: This trial is the first report of the use of a microbial consortium as an alternative to FMT in advanced cancer patients receiving ICI and the results justify the further development of microbial consortia as a therapeutic co-intervention for ICI treatment in cancer

Historical anthropogenic stressors affect bird ecology and feather development in neotropical forests

Fragmentation and habitat loss driven by agricultural expansion have significantly affected bird ecology. Additionally, the growing use of agrochemicals impacts ecosystems and avian communities. Tools such as isotopic analysis provide reliable proxies for assessing organisms' habitat use and diet, and can also reflect environmental alterations, such as increased input of agrochemicals and shifts in baseline resources. By employing stable isotope analysis of carbon ( δ 13 C) and nitrogen ( δ 15 N) on bird feathers over an extensive timescale, we investigated whether human impacts have changed their habitat use, diet, and feather development in two key regions of the Brazilian Atlantic Forest: the Pernambuco and Serra do Mar areas of endemism. We analyzed feathers from 1778 museum specimens, categorized by region, trophic guild and temporal groups (historical and modern). Furthermore, we examined fault bars in the wing and tail feathers of 856 specimens to assess changes in feather development. In Serra do Mar, comparisons showed a significant decline in δ 15 N over time, while δ 13 C remained stable. These findings suggest that, in addition to habitat loss, agrochemical runoff may indirectly affect bird communities in this region, known for its high agricultural activity. In contrast, isotopic changes in Pernambuco were significant for only a few species, suggesting that habitat use and diet shifts in this region are primarily driven by fragmentation and forest loss. Moreover, we noted a decline in feather quality over time, underscoring the negative effects of human stressors on feather development across the Atlantic Forest birds